nimesulide and flurbiprofen

nimesulide has been researched along with flurbiprofen in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (27.78)18.2507
2000's5 (27.78)29.6817
2010's8 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A1
Bauer, R; Goeters, S; Hempel, B; Imming, P; Krause, E; Lohmann, K; Ramadan, M; Watzer, B1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Amodeo, C; De Marco, M; Gambarini, G1
Lomeo, G; Monea, P; Rossi, M; Scaricabarozzi, I; Trezzani, R; Tringali, G1
Scaricabarozzi, I; Scolari, G; Vargiu, G1
Coppi, G1
Garofalo, A; Iurato, S; Montoneri, C; Scaricabarozzi, I; Trezzani, R1
Caron, G; Ermondi, G; Lawrence, R; Longo, D1
Han, JA; Kim, SR; Lee, ME; Park, JH; Park, JS; Park, SC1
Kulmacz, RJ; Tsai, AL; Wu, G1
Lee, JY; Sidhu, RS; Smith, WL; Yuan, C1

Reviews

1 review(s) available for nimesulide and flurbiprofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for nimesulide and flurbiprofen

ArticleYear
[A clinical study of the efficacy and tolerance of nimesulide compared to flurbiprofen and sodium diclofenac in the prevention and treatment of postoperative pain and inflammatory symptoms in dentistry].
    Minerva stomatologica, 1992, Volume: 41, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Tolerance; Female; Flurbiprofen; Humans; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Sulfonamides; Surgery, Oral

1992
[Clinical study of the efficacy of and tolerance to nimesulide in suppository formulation in pain-inflammatory pathologies of the ear, nose, and throat].
    Minerva medica, 1991, Volume: 82, Issue:12

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Flurbiprofen; Humans; Inflammation; Male; Middle Aged; Otorhinolaryngologic Diseases; Pain; Sulfonamides; Suppositories

1991
[The nimesulide treatment of inflammation and posttraumatic pain in maxillofacial surgery. A controlled study versus flurbiprofen].
    Minerva stomatologica, 1990, Volume: 39, Issue:12

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Tolerance; Flurbiprofen; Humans; Inflammation; Pain, Postoperative; Postoperative Complications; Sulfonamides; Surgery, Oral

1990
[Pharmacological and clinical profile of tiaprofenic acid].
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 1990, Volume: 10 Suppl 28

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Feprazone; Flurbiprofen; Guinea Pigs; Humans; Otorhinolaryngologic Diseases; Propionates; Rats; Sulfonamides

1990
[Clinical study of the efficacy and tolerability of nimesulide in suppositories compared to flurbiprofen in gynecology].
    Minerva ginecologica, 1990, Volume: 42, Issue:10

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Drug Evaluation; Drug Tolerance; Female; Flurbiprofen; Genital Diseases, Female; Humans; Sulfonamides; Suppositories

1990

Other Studies

12 other study(ies) available for nimesulide and flurbiprofen

ArticleYear
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism

2005
Chamazulene carboxylic acid and matricin: a natural profen and its natural prodrug, identified through similarity to synthetic drug substances.
    Journal of natural products, 2006, Volume: 69, Issue:7

    Topics: Achillea; Anti-Inflammatory Agents, Non-Steroidal; Azulenes; Carboxylic Acids; Cycloheptanes; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Germany; Lactones; Matricaria; Molecular Structure; Pharmaceutical Preparations; Prodrugs; Sesquiterpenes; Sesquiterpenes, Guaiane

2006
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Docking studies on NSAID/COX-2 isozyme complexes using contact statistics analysis.
    Journal of computer-aided molecular design, 2004, Volume: 18, Issue:11

    Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Flurbiprofen; Humans; Isoenzymes; Lactones; Membrane Proteins; Models, Molecular; Models, Statistical; Molecular Conformation; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyrazoles; Sulfonamides; Sulfones

2004
Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner.
    Mechanisms of ageing and development, 2008, Volume: 129, Issue:12

    Topics: Aspirin; Caveolin 1; Celecoxib; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fibroblasts; Flurbiprofen; Humans; Ibuprofen; Kinetics; Models, Biological; NF-kappa B; Nitrobenzenes; Pyrazoles; Reactive Oxygen Species; Skin; Skin Aging; Sulfonamides; Tumor Suppressor Protein p53

2008
Cyclooxygenase competitive inhibitors alter tyrosyl radical dynamics in prostaglandin H synthase-2.
    Biochemistry, 2009, Dec-22, Volume: 48, Issue:50

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; Catalysis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Enzyme Activation; Enzyme Stability; Flurbiprofen; Free Radicals; Humans; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thermodynamics; Tyrosine

2009
Comparison of cyclooxygenase-1 crystal structures: cross-talk between monomers comprising cyclooxygenase-1 homodimers.
    Biochemistry, 2010, Aug-24, Volume: 49, Issue:33

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catalytic Domain; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Diclofenac; Flurbiprofen; Ligands; Models, Molecular; Protein Binding; Protein Conformation; Protein Multimerization; Sheep; Sulfonamides

2010