Compounds > nimesulide

nimesulide and dinoprostone

nimesulide has been researched along with dinoprostone in 95 studies

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (18.95)18.2507
2000's60 (63.16)29.6817
2010's16 (16.84)24.3611
2020's1 (1.05)2.80

Authors

AuthorsStudies
Elagib, KE; Goldfarb, AN; Munson, KM; Peterson, RT; Sweetser, DA; Yeh, JR1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Biollaz, J; Buclin, T; Macciocchi, A; Munafo, A; Steinhäuslin, F1
Harada, Y; Hatanaka, K; Katori, M; Kawamura, M; Majima, M; Ogino, K; Ogino, M; Ohno, T; Saito, M; Taketani, Y; Yamamoto, K; Yamamoto, S1
Furukawa, M; Horie, Y; Nakatsugi, S; Terada, N; Yoshimura, T1
Furukawa, M; Nakatsugi, S; Sugimoto, N1
Deguchi, Y; Furukawa, K; Inui, K; Noda, K; Taniguchi, Y; Yokoyama, K1
Bell, RL; Hulkower, KI; Otis, ER; Wernimont, AK1
Hirata, T; Kato, S; Takeuchi, K; Ukawa, H; Yamakuni, H1
Hirata, T; Kitamura, M; Takeuchi, K; Ukawa, H1
Famaey, JP1
Bennett, PR; Nathanielsz, PW; Shinozuka, N; Unno, N; Wong, CH; Wu, WX1
Debuchi, H; Ikesue, A; Nakamura, T; Noda, K; Shimeno, H; Taniguchi, Y; Toda, A; Yokoyama, K1
Ma, XH; Nathanielsz, PW; Unno, N; Wu, WX1
Harada, Y; Hatanaka, K; Kawamura, M; Ogino, K; Ogino, M; Ohno, T; Saito, M; Yang, Q1
Holland, E; Knox, AJ; Pang, L1
Hirst, JJ; Poore, KR; Young, IR1
Giuliano, F; Warner, TD1
Agrewala, JN; Kulkarni, SK; Raghavendra, V1
Akiguchi, I; Kawasaki, T; Matsuo, A; Miyamoto, K; Oka, N; Satoi, H1
Artru, AA; Kaplanski, J; Koyfman, L; Rubin, M; Shapira, Y; Talmor, D1
Mitchell, JA; Pepper, JR; Stanford, SJ1
Casamenti, F; Pepeu, G; Prosperi, C; Scali, C; Vannucchi, MG1
González, JD; Llinás, MT; Rivera, J; Rodríguez, F; Salazar, FJ1
Grigsby, PL; Hirst, JJ; Jenkin, G; Poore, KR1
Ballerio, R; Bianchib, M; Buccellati, C; Sala, A1
Kawamori, T; Nakatsugi, S; Wakabayashi, K; Watanabe, K1
Azab, AN; Kaplanski, J1
Di Battista, JA; Fahmi, H; He, Y; Martel-Pelletier, J; Pelletier, JP; Zhang, M1
Azab, AN; Kaplanski, J; Shemi, D1
An, SJ; Ferreri, NR; McGiff, JC; Wang, D; Wang, WH1
Kömhoff, M; Nüsing, RM; Peters, M; Reinalter, SC; Seyberth, HW1
Keelan, JA; Mitchell, MD; Sato, TA1
Kankuri, E; Korpela, R; Moilanen, E; Paakkari, I; Vaali, K; Vapaatalo, H1
Blatteis, CM; Li, S; Llanos-Q, J; Steiner, AA1
Bazan, NG; Chen, C; Magee, JC1
Kawamori, T; Wakabayashi, K1
Llinas, MT; López, R; Roig, F; Salazar, FJ1
Del Soldato, P; Gray, PA; Mitchell, JA; Parikh, A; Scadding, GK; Vojnovic, I; Warner, TD1
Gajkowska, B; Godlewski, MM; Lamparska-Przybysz, M; Motyl, T1
Huang, JA; Li, JY; Luo, HS; Mei, Q; Tian, G; Yu, BP; Yu, JP1
Boje, KM; Jaworowicz, D; Raybon, JJ1
Bianchi, M; Ho, L; McManus, T; Pasinetti, GM; Pompl, PN; Qin, W1
Baylas, H; Huseyinov, A; Vardar, S1
Cai, SH; Li, XH; Li, XK; Ren, XD; Tang, FX; Zhong, XY1
Bruemmer, D; Duffy, JP; Eibl, G; Hines, OJ; Law, RE; Okada, Y; Reber, HA1
Hagihara, K; Koshimizu, K; Murakami, A; Ohigashi, H; Takahashi, D1
Bennett, P; Pan, H; Sawdy, R; Sullivan, M1
Ito, D; Iwase, M; Kimura, T; Kondo, G; Nagumo, M; Ohashi, M; Watanabe, H1
Jänicke, RU; Schulze-Osthoff, K; Totzke, G1
Belton, O; Bresnihan, B; Duffy, T; FitzGerald, D; FitzGerald, O1
Kawakami, Y; Maru, E; Sugiura, H; Suzuki, K; Takemiya, T; Yamagata, K; Yasuda, S1
Cai, SH; Li, JJ; Li, XH; Ren, XD; Sun, P; Zhang, HW; Zhang, YL1
Chatterjee, A; Shaik, MS; Singh, M1
Fogel-Petrovic, M; Knight, DA; Long, JA; Thompson, PJ; Upham, JW1
Candelario-Jalil, E; Fiebich, BL; García-Cabrera, M; González-Falcón, A; León, OS1
Cella, M; Farina, M; Franchi, A; Ribeiro, M1
Azab, AN; Kaplanski, J; Kobal, S; Rubin, M1
Boros, LG; Eibl, G; Hines, OJ; Liu, J; Okada, Y; Reber, HA; Takata, Y1
Kondo, M; Nagai, A; Nakata, J; Nohara, M; Takemiya, T; Tamaoki, J; Yamagata, K1
Reimsnider, SK; Wood, CE1
Guo, GL; Yao, ZX; Zhang, XH1
Arakawa, T; Fujiwara, Y; Hamaguchi, M; Hayakawa, T; Higuchi, K; Okuyama, M; Oshitani, N; Sasaki, E; Sugawa, T; Tominaga, K; Watanabe, T1
Reimsnider, S; Wood, CE1
Souza, GE; Werner, MF; Zampronio, AR1
Amsterdam, A; Armon, L; Ben-Ami, I; Dantes, A; Freimann, S; Friedler, S; Raziel, A; Ron-El, R; Seger, R; Strassburger, D1
Favrais, G; Gressens, P; Lelièvre, V; Schwendimann, L1
Becker, TL; Gambero, A; Maróstica, M; Pedrazzoli, J1
Bianchi, M; Ferrario, P; Franchi, S; Martucci, C; Sacerdote, P1
Dawson, D; Eibl, G; Funahashi, H; Hines, OJ; Huynh, NA; Reber, HA; Satake, M1
Fujimura, T; Fushida, S; Kinami, S; Miyashita, T; Ninomiya, I; Ohta, T; Oyama, K1
Deasy, BM; McKenna, SL; O'Donovan, TR; O'Sullivan, GC; O'Sullivan-Coyne, G1
Abe, Y; Hirata, I; Inoue, T; Katsu, K; Maemura, K; Morita, E; Murano, M; Murano, N; Nishikawa, T; Toshina, K; Yasumoto, S1
Butterworth, RF; Desjardins, P; Gu, B1
Hu, YQ; Li, J; Li, W; Xu, RJ; Zhang, HH; Zhuo, GC1
Cho, CH; Li, P; Liu, X; Wu, YD; Xu, CM; Yu, ZL; Zhang, ST1
Buyse, M; Farinotti, R; Zrieki, A1
Fu, J; Liang, M; Yang, H1
Kankaanranta, H; Kerola, M; Kosonen, O; Moilanen, E; Sarna, S; Vuolteenaho, K1
Bility, MT; Gonzalez, FJ; Kang, BH; Peters, JM; Zhu, B1
Beninati, S; Gismondi, A; Lentini, A; Provenzano, B; Rossi, S; Tabolacci, C1
Cerella, C; Dicato, M; Diederich, M; Sobolewski, C1
Jancar, S; Peters-Golden, M; Stumm, CL; Wettlaufer, SH1
Hooper, SB; Moss, TJ; Wallace, MJ; Westover, AJ1
Arenas Jiménez, MI; Fernández-Martínez, AB; Lucio Cazaña, FJ1
Cho, YM; Hasumura, M; Hirose, M; Imai, T; Nishikawa, A; Ogawa, K; Ota, Y; Oyamada, T; Takami, S1
Alger, BE; Dean, SL; Hoffman, JF; McCarthy, MM; Wang, M; Wright, CL1
Harvey, BS; Nicotra, LL; Smid, SD; Vu, M1
Battani, KA; Lindgren, CA; Morford, JJ; Newman, ZL; Ryan, SB; Su, Z1
Bonanno, G; De Cristofaro, R; Iachininoto, MG; Locatelli, F; Mariotti, A; Nuzzolo, ER; Procoli, A; Rutella, S1
Caiazzo, E; Cicala, C; Ialenti, A; Iuvone, T; Lapucci, A; Lavecchia, A; Maione, F; Morello, S; Paccosi, S; Parenti, A; Schrader, J; Steckel, B1
Bezerra-Santos, CR; Filgueiras, LR; Jancar, S; Lima, AL; Pacheco de Oliveira, MT; Piuvezam, MR; Ramalho, TR1
Costa, EMS; da Silva Souza, KG; de Brito, MTFM; de Lima, MVD; de Matos, RF; Fonseca, AAD; Mendonça, LCV; Monteiro, MC; Vieira, JMDS1
Argolo, DS; Arruda, MR; Bispo-da-Silva, A; Costa, MFD; Costa, SL; El-Bachá, RS; Grangeiro, MS; Jesus, EEV; Jesus, LB; Pinheiro, AM; Santos, AB; Santos, RGD1
Hanaoka, J; Kataoka, Y; Kawaguchi, Y; Ohshio, Y; Okamoto, K; Shiratori, T; Suzuki, T; Ueda, K; Watanabe, A1

Reviews

2 review(s) available for nimesulide and dinoprostone

ArticleYear
In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2

1997
COX-2 and iNOS, good targets for chemoprevention of colon cancer.
    BioFactors (Oxford, England), 2000, Volume: 12, Issue:1-4

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Humans; Isoenzymes; Membrane Proteins; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Rats; Receptors, Prostaglandin E; Sulfonamides

2000

Trials

4 trial(s) available for nimesulide and dinoprostone

ArticleYear
Pathogenetic role of cyclooxygenase-2 in hyperprostaglandin E syndrome/antenatal Bartter syndrome: therapeutic use of the cyclooxygenase-2 inhibitor nimesulide.
    Clinical pharmacology and therapeutics, 2001, Volume: 70, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Bartter Syndrome; Blood Platelets; Child; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Indomethacin; Isoenzymes; Kidney; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Sulfonamides; Thromboxane B2

2001
Effects of selective cyclooxygenase-2 inhibition on gingival tissue levels of prostaglandin E2 and prostaglandin F2alpha and clinical parameters of chronic periodontitis.
    Journal of periodontology, 2003, Volume: 74, Issue:1

    Topics: Adult; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dental Plaque Index; Dental Scaling; Dinoprost; Dinoprostone; Double-Blind Method; Female; Follow-Up Studies; Gingiva; Humans; Isoenzymes; Male; Matched-Pair Analysis; Membrane Proteins; Middle Aged; Naproxen; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Placebos; Prostaglandin-Endoperoxide Synthases; Root Planing; Statistics as Topic; Statistics, Nonparametric; Sulfonamides

2003
Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis.
    Drugs, 2003, Volume: 63 Suppl 1

    Topics: Acute Disease; Administration, Oral; Arthralgia; Arthritis; Cyclooxygenase 1; Cyclooxygenase 2; Diclofenac; Dinoprostone; Double-Blind Method; Humans; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides; Synovial Fluid

2003
Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Ibuprofen; Male; Nabumetone; Sulfonamides; Thromboxane B2

2009

Other Studies

89 other study(ies) available for nimesulide and dinoprostone

ArticleYear
Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation.
    Nature chemical biology, 2009, Volume: 5, Issue:4

    Topics: Animals; Animals, Genetically Modified; beta Catenin; Cell Differentiation; Dinoprostone; Gene Expression Regulation; Humans; K562 Cells; Nitrobenzenes; Oncogene Proteins; Small Molecule Libraries; Sulfonamides; Transcription Factors; Zebrafish; Zebrafish Proteins

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Renal effects of nimesulide in furosemide-treated subjects.
    Drugs, 1993, Volume: 46 Suppl 1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Drug Interactions; Electrolytes; Furosemide; Hemodynamics; Humans; Kidney; Male; Sulfonamides

1993
Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy.
    Prostaglandins, 1996, Volume: 51, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Azo Compounds; Blotting, Western; Carrageenan; Cell Count; Cells, Cultured; Coloring Agents; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Excipients; Inflammation; Isoenzymes; Leukocytes; Male; Nitrobenzenes; Pleura; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Thromboxane B2; Trypan Blue

1996
Effects of nimesulide, a preferential cyclooxygenase-2 inhibitor, on carrageenan-induced pleurisy and stress-induced gastric lesions in rats.
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 55, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Excipients; Exudates and Transudates; Gastric Mucosa; Gastritis; Ibuprofen; Indomethacin; Isoenzymes; Male; Membrane Proteins; Pleurisy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stress, Physiological; Sulfonamides

1996
Effects of non-steroidal anti-inflammatory drugs on prostaglandin E2 production by cyclooxygenase-2 from endogenous and exogenous arachidonic acid in rat peritoneal macrophages stimulated with lipopolysaccharide.
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 55, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Ibuprofen; Indomethacin; Isoenzymes; Lipopolysaccharides; Macrophages, Peritoneal; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides

1996
Inhibition of brain cyclooxygenase-2 activity and the antipyretic action of nimesulide.
    European journal of pharmacology, 1997, Jul-09, Volume: 330, Issue:2-3

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Brain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Fever; Hypothalamus; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides

1997
Stimulus dependence of non-steroidal antiinflammatory drug potency in a cellular assay of prostaglandin H synthase-2.
    European journal of pharmacology, 1997, Jul-16, Volume: 331, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Drug Interactions; Humans; Ibuprofen; Indans; Indomethacin; Interleukin-1; Meclofenamic Acid; Nitrobenzenes; Okadaic Acid; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides; Tumor Necrosis Factor-alpha

1997
Cyclo-oxygenase isozymes in mucosal ulcergenic and functional responses following barrier disruption in rat stomachs.
    British journal of pharmacology, 1997, Volume: 122, Issue:3

    Topics: Animals; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Gastric Acid; Gastric Mucosa; Indomethacin; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Rats; Stomach; Stomach Ulcer; Sulfonamides; Taurocholic Acid

1997
Effects of selective cyclooxygenase-2 inhibitors on alkaline secretory and mucosal ulcerogenic responses in rat duodenum.
    Life sciences, 1997, Volume: 61, Issue:16

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bicarbonates; Cyclooxygenase Inhibitors; Dinoprostone; Duodenal Ulcer; Duodenum; Gastric Acid; Histamine; Hydrogen-Ion Concentration; Indomethacin; Intestinal Mucosa; Male; Nitrobenzenes; Rats; Rats, Sprague-Dawley; Sulfonamides

1997
Prostaglandin regulation of fetal plasma adrenocorticotropin and cortisol concentrations in late-gestation sheep.
    Biology of reproduction, 1998, Volume: 58, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Blood Gas Analysis; Dinoprostone; Female; Fetus; Hydrocortisone; Labor, Obstetric; Myometrium; Pregnancy; Pregnancy, Animal; Prostaglandin Antagonists; Prostaglandins; Radioimmunoassay; Sheep; Sulfonamides

1998
Inhibition by nimesulide of prostaglandin production in rat macrophages.
    Drugs under experimental and clinical research, 1998, Volume: 24, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Evaluation, Preclinical; Enzyme Induction; Isoenzymes; Macrophages, Peritoneal; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stimulation, Chemical; Sulfonamides; Zymosan

1998
Inhibition of prostaglandin production by nimesulide is accompanied by changes in expression of the cassette of uterine labor-related genes in pregnant sheep.
    Endocrinology, 1998, Volume: 139, Issue:7

    Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Fetal Blood; Gene Expression Regulation; Heat-Shock Proteins; Isoenzymes; Labor, Obstetric; Phospholipases A; Pregnancy; Pregnancy, Animal; Prostaglandin-Endoperoxide Synthases; Receptors, Estrogen; Receptors, Oxytocin; RNA, Messenger; Sheep; Sulfonamides; Uterus

1998
Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat.
    Prostaglandins & other lipid mediators, 1998, Volume: 55, Issue:5-6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gastric Juice; Indomethacin; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Pleurisy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sulfonamides; Thromboxane B2

1998
Impaired cAMP production in human airway smooth muscle cells by bradykinin: role of cyclooxygenase products.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Adult; Bradykinin; Calcimycin; Cells, Cultured; Cyclic AMP; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Dexamethasone; Dinoprostone; Enzyme Induction; Female; Humans; Indomethacin; Isoenzymes; Isoproterenol; Male; Membrane Proteins; Middle Aged; Muscle, Smooth; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Receptor, Bradykinin B2; Receptors, Bradykinin; Sulfonamides; Trachea

1998
Efficacy of the selective prostaglandin synthase type 2 inhibitor nimesulide in blocking basal prostaglandin production and delaying glucocorticoid-induced premature labor in sheep.
    American journal of obstetrics and gynecology, 1999, Volume: 180, Issue:5

    Topics: Animals; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprost; Dinoprostone; Electromyography; Female; Fetal Blood; Glucocorticoids; Naphthaleneacetic Acids; Obstetric Labor, Premature; Pregnancy; Prostaglandins; Sheep; Sulfonamides; Uterus

1999
Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs.
    British journal of pharmacology, 1999, Volume: 126, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Blood Pressure; Carcinoma; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salicylates; Substrate Specificity; Sulfonamides; Sulindac; Thromboxane B2; Tumor Cells, Cultured

1999
Role of centrally administered melatonin and inhibitors of COX and NOS in LPS-induced hyperthermia and adipsia.
    Prostaglandins, leukotrienes, and essential fatty acids, 1999, Volume: 60, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cyclooxygenase Inhibitors; Dinoprostone; Fever; Indomethacin; Lipopolysaccharides; Male; Melatonin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sulfonamides; Thirst; Time Factors

1999
The action mechanism of cyclooxygenase-2 inhibitor for treatment of experimental allergic neuritis.
    Muscle & nerve, 1999, Volume: 22, Issue:12

    Topics: Animals; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Immunohistochemistry; Isoenzymes; Lipoxygenase Inhibitors; Male; Movement; Nerve Fibers; Neuritis, Autoimmune, Experimental; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Sciatic Nerve; Sciatic Neuropathy; Sulfonamides

1999
Inhibition of cyclooxygenase 2 by nimesulide decreases prostaglandin E2 formation but does not alter brain edema or clinical recovery after closed head injury in rats.
    Journal of neurosurgical anesthesiology, 2000, Volume: 12, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Body Water; Brain Chemistry; Brain Edema; Cerebral Cortex; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Follow-Up Studies; Halothane; Head Injuries, Closed; Hypothalamus; Injections, Intraperitoneal; Isoenzymes; Neurologic Examination; Peroxidases; Prostaglandin-Endoperoxide Synthases; Random Allocation; Rats; Rats, Sprague-Dawley; Sulfonamides

2000
Cyclooxygenase-2 regulates granulocyte-macrophage colony-stimulating factor, but not interleukin-8, production by human vascular cells: role of cAMP.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arteriosclerosis; Aspirin; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indans; Indomethacin; Interleukin-1; Interleukin-8; Isoenzymes; Mammary Arteries; Meloxicam; Membrane Proteins; Muscle, Smooth, Vascular; Neutrophils; Prostaglandin-Endoperoxide Synthases; Saphenous Vein; Sulfonamides; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha

2000
Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease.
    The European journal of neuroscience, 2000, Volume: 12, Issue:6

    Topics: Acetylcholine; Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Choline O-Acetyltransferase; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Encephalitis; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Gliosis; Interleukin-1; Isoenzymes; Male; Microscopy, Electron; Nerve Degeneration; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin-Endoperoxide Synthases; Quisqualic Acid; Rats; Rats, Wistar; Sulfonamides

2000
Renal changes induced by a cyclooxygenase-2 inhibitor during normal and low sodium intake.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:2

    Topics: Animals; Arachidonic Acid; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Isoenzymes; Kidney; Lithium; Male; Meclofenamic Acid; Platelet Aggregation; Platelet Count; Prostaglandin-Endoperoxide Synthases; Renal Circulation; Sodium, Dietary; Sulfonamides; Urodynamics

2000
Inhibition of premature labor in sheep by a combined treatment of nimesulide, a prostaglandin synthase type 2 inhibitor, and atosiban, an oxytocin receptor antagonist.
    American journal of obstetrics and gynecology, 2000, Volume: 183, Issue:3

    Topics: Animals; Arteries; Blood Glucose; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprost; Dinoprostone; Drug Therapy, Combination; Electromyography; Female; Fetal Blood; Fetus; Glucocorticoids; Lactic Acid; Obstetric Labor, Premature; Oxygen; Pregnancy; Receptors, Oxytocin; Sheep; Sulfonamides; Uterus; Vasotocin

2000
Tramadol anti-inflammatory activity is not related to a direct inhibitory action on prostaglandin endoperoxide synthases.
    European journal of pain (London, England), 2000, Volume: 4, Issue:4

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; In Vitro Techniques; Isoenzymes; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2; Tramadol

2000
A reduction of tumor necrosis factor-alpha in paw exudate of lipopolysaccharide treated rats by nimesulide.
    Life sciences, 2001, Feb-23, Volume: 68, Issue:14

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dinoprostone; Edema; Exudates and Transudates; Indomethacin; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Sulfonamides; Tumor Necrosis Factor-alpha

2001
Differential regulation of interleukin-1 beta-induced cyclooxygenase-2 gene expression by nimesulide in human synovial fibroblasts.
    Clinical and experimental rheumatology, 2001, Volume: 19, Issue:1 Suppl 22

    Topics: Arthritis, Rheumatoid; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Interleukin-1; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Naproxen; Nitrobenzenes; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides; Synovial Membrane

2001
Time-dependent effect of LPS on PGE2 and TNF-alpha production by rat glial brain culture: influence of COX and cytokine inhibitors.
    Journal of endotoxin research, 2000, Volume: 6, Issue:5

    Topics: Animals; Brain; Cells, Cultured; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Indomethacin; Kinetics; Lipopolysaccharides; Neuroglia; Pentoxifylline; Rats; Sulfonamides; Tumor Necrosis Factor-alpha

2000
CaR-mediated COX-2 expression in primary cultured mTAL cells.
    American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:4

    Topics: Animals; Calcium; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression; Isoenzymes; Loop of Henle; Male; Nitrobenzenes; Peptides; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptors, Calcium-Sensing; Receptors, Cell Surface; RNA, Messenger; Sulfonamides

2001
Regulation of prostaglandin production in an immortalized human myometrial cell line by cytokines and non-steroidal anti-inflammatory drugs.
    European journal of obstetrics, gynecology, and reproductive biology, 2002, Jan-10, Volume: 100, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Enzyme Inhibitors; Etodolac; Female; Furans; Humans; Indomethacin; Interleukin-1; Prostaglandins; Sulfonamides; Tumor Necrosis Factor-alpha

2002
Effects of a COX-2 preferential agent nimesulide on TNBS-induced acute inflammation in the gut.
    Inflammation, 2001, Volume: 25, Issue:5

    Topics: Acute Disease; Animals; Aspirin; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Disease Models, Animal; Drug Evaluation, Preclinical; Indomethacin; Inflammation; Inflammatory Bowel Diseases; Isoenzymes; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides; Trinitrobenzenesulfonic Acid

2001
Differential inhibition by nimesulide of the early and late phases of intravenous- and intracerebroventricular-LPS-induced fever in guinea pigs.
    Neuroimmunomodulation, 2001, Volume: 9, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Brain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Fever; Guinea Pigs; Indomethacin; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Isoenzymes; Lipopolysaccharides; Male; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides

2001
Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity.
    Journal of neurophysiology, 2002, Volume: 87, Issue:6

    Topics: Action Potentials; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dendrites; Dentate Gyrus; Dinoprostone; Excitatory Postsynaptic Potentials; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Nitrobenzenes; Organ Culture Techniques; Perforant Pathway; Presynaptic Terminals; Prostaglandin-Endoperoxide Synthases; Signal Transduction; Sulfonamides; Synapses

2002
COX-2 and prostanoid receptors: good targets for chemoprevention.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2002, Volume: 21, Issue:2

    Topics: Animals; Breast Neoplasms; Celecoxib; Cell Transformation, Neoplastic; Chemoprevention; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Female; Humans; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Sulfonamides

2002
Role of nitric oxide and cyclooxygenase-2 in regulating the renal hemodynamic response to norepinephrine.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:2

    Topics: Animals; Blood Pressure; Cyclooxygenase 2; Dinoprostone; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Isoenzymes; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Prostaglandin-Endoperoxide Synthases; Renal Circulation; Sulfonamides; Vasoconstriction

2003
Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Benzene Derivatives; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Furans; Humans; Indomethacin; Ionophores; Isoenzymes; Leukotrienes; Lipopolysaccharides; Lipoxygenase; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2

2002
Colocalization of BAX with BID and VDAC-1 in nimesulide-induced apoptosis of human colon adenocarcinoma COLO 205 cells.
    Anti-cancer drugs, 2002, Volume: 13, Issue:10

    Topics: Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carrier Proteins; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Intracellular Membranes; Isoenzymes; Membrane Proteins; Microscopy, Confocal; Microscopy, Immunoelectron; Porins; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Tumor Cells, Cultured; Voltage-Dependent Anion Channel 1; Voltage-Dependent Anion Channels

2002
[Influence of selective cyclooxygenase-2 inhibitor on proliferation of human gastric cancer cells].
    Ai zheng = Aizheng = Chinese journal of cancer, 2002, Volume: 21, Issue:6

    Topics: Adenocarcinoma; Apoptosis; Cell Cycle; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Isoenzymes; Prostaglandin-Endoperoxide Synthases; Stomach Neoplasms; Sulfonamides; Tumor Cells, Cultured

2002
Neuroinflammatory role of prostaglandins during experimental meningitis: evidence suggestive of an in vivo relationship between nitric oxide and prostaglandins.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:1

    Topics: Animals; Blood-Brain Barrier; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Guanidines; Isoenzymes; Lipopolysaccharides; Male; Meningitis; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulfonamides

2003
A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:6

    Topics: Amyotrophic Lateral Sclerosis; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Isoenzymes; Mice; Mice, Transgenic; Motor Activity; Mutation; Prostaglandin-Endoperoxide Synthases; Spinal Cord; Sulfonamides; Superoxide Dismutase

2003
Synergistic effects of nimesulide and 5-fluorouracil on tumor growth and apoptosis in the implanted hepatoma in mice.
    World journal of gastroenterology, 2003, Volume: 9, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Apoptosis; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Fluorouracil; Liver Neoplasms, Experimental; Mice; Microscopy, Electron; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Sulfonamides; Tumor Suppressor Protein p53

2003
PGE(2) is generated by specific COX-2 activity and increases VEGF production in COX-2-expressing human pancreatic cancer cells.
    Biochemical and biophysical research communications, 2003, Jul-11, Volume: 306, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Arachidonic Acid; Blotting, Western; Cell Movement; Cells, Cultured; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Humans; Intercellular Signaling Peptides and Proteins; Isoenzymes; Lymphokines; Membrane Proteins; Models, Biological; Pancreatic Neoplasms; Plasmids; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Time Factors; Transfection; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
Combinatorial effects of nonsteroidal anti-inflammatory drugs and food constituents on production of prostaglandin E2 and tumor necrosis factor-alpha in RAW264.7 murine macrophages.
    Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Catechin; Cell Line; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Food Analysis; Food-Drug Interactions; Genistein; Indicators and Reagents; Indomethacin; Interferon-gamma; Isothiocyanates; Lipopolysaccharides; Macrophages; Mice; Protein Biosynthesis; Spectrophotometry, Infrared; Sulfonamides; Tumor Necrosis Factor-alpha

2003
Effect of selective vs. non-selective cyclo-oxygenase inhibitors on fetal membrane prostaglandin synthesis.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2003, Volume: 23, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Extraembryonic Membranes; Female; Furans; Humans; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Meloxicam; Membrane Proteins; Pregnancy; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thiazines; Thiazoles

2003
Suppressive effect of selective cyclooxygenase-2 inhibitor on cytokine release in human neutrophils.
    International immunopharmacology, 2003, Volume: 3, Issue:10-11

    Topics: Adult; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Humans; Isoenzymes; Membrane Proteins; Neutrophils; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Superoxides

2003
Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition.
    Oncogene, 2003, Sep-11, Volume: 22, Issue:39

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Caspase 3; Caspases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; fas Receptor; Female; HeLa Cells; Humans; Isoenzymes; Membrane Glycoproteins; Membrane Proteins; Mitochondria; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Receptors, Tumor Necrosis Factor; Sulfonamides; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2003
Inducible brain COX-2 facilitates the recurrence of hippocampal seizures in mouse rapid kindling.
    Prostaglandins & other lipid mediators, 2003, Volume: 71, Issue:3-4

    Topics: Animals; Brain; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Enzyme Induction; Hippocampus; In Situ Hybridization; Isoenzymes; Kindling, Neurologic; Mice; Mice, Knockout; Neurons; Prostaglandin-Endoperoxide Synthases; Recurrence; RNA, Messenger; Seizures; Sulfonamides

2003
Nimesulide inhibits tumor growth in mice implanted hepatoma: overexpression of Bax over Bcl-2.
    Acta pharmacologica Sinica, 2003, Volume: 24, Issue:10

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Isoenzymes; Liver Neoplasms, Experimental; Male; Mice; Neoplasm Transplantation; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Sulfonamides; Tumor Cells, Cultured

2003
Effect of a selective cyclooxygenase-2 inhibitor, nimesulide, on the growth of lung tumors and their expression of cyclooxygenase-2 and peroxisome proliferator- activated receptor-gamma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-15, Volume: 10, Issue:4

    Topics: Animals; Apoptosis; Blotting, Western; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Horseradish Peroxidase; Humans; Immunoenzyme Techniques; Immunohistochemistry; In Situ Nick-End Labeling; Isoenzymes; Lung Neoplasms; Membrane Proteins; Mice; Mice, Nude; Neoplasm Transplantation; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Sulfonamides; Time Factors; Transcription Factors

2004
Activated human dendritic cells express inducible cyclo-oxygenase and synthesize prostaglandin E2 but not prostaglandin D2.
    Immunology and cell biology, 2004, Volume: 82, Issue:1

    Topics: Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dendritic Cells; Dinoprostone; Flow Cytometry; Humans; Immunohistochemistry; Interleukin-10; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides

2004
Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat.
    Brain research, 2004, May-08, Volume: 1007, Issue:1-2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cerebral Infarction; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Immunoassay; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Neurologic Examination; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazolium Salts; Time Factors; Treatment Outcome

2004
Effects of aminoguanidine and cyclooxygenase inhibitors on nitric oxide and prostaglandin production, and nitric oxide synthase and cyclooxygenase expression induced by lipopolysaccharide in the estrogenized rat uterus.
    Neuroimmunomodulation, 2004, Volume: 11, Issue:3

    Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Down-Regulation; Embryo Loss; Estrogens; Female; Guanidines; Indomethacin; Inflammation; Isoenzymes; Lipopolysaccharides; Meloxicam; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Sulfonamides; Thiazines; Thiazoles; Uterus

2004
Effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on cardiovascular alterations in endotoxemia.
    Cardiology, 2005, Volume: 103, Issue:2

    Topics: Animals; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Echocardiography, Doppler; Endotoxemia; Heart Diseases; Interleukin-1; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides; Tumor Necrosis Factor-alpha

2005
Growth stimulation of COX-2-negative pancreatic cancer by a selective COX-2 inhibitor.
    Cancer research, 2005, Feb-01, Volume: 65, Issue:3

    Topics: Animals; Cell Growth Processes; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Humans; Membrane Proteins; Mice; Mice, Nude; Neovascularization, Pathologic; NIH 3T3 Cells; Pancreatic Neoplasms; PPAR gamma; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Vascular Endothelial Growth Factor A

2005
Augmentation of allergic inflammation in the airways of cyclooxygenase-2-deficient mice.
    Respirology (Carlton, Vic.), 2005, Volume: 10, Issue:2

    Topics: Animals; Arachidonic Acid; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cysteine; Dinoprostone; Female; Immunoglobulin E; Inflammation; Interleukin-13; Leukotrienes; Lung; Male; Metaplasia; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Sulfonamides

2005
Does reduction of circulating prostaglandin E2 reduce fetal hypothalamic-pituitary-adrenal axis activity?
    Journal of the Society for Gynecologic Investigation, 2005, Volume: 12, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Female; Heart Rate, Fetal; Hydrocortisone; Hypothalamo-Hypophyseal System; Maternal-Fetal Exchange; Pituitary-Adrenal System; Placenta; Pregnancy; Pregnancy, Animal; Resveratrol; Sheep; Stilbenes; Sulfonamides

2005
[The effect of selective cyclooxygenase-2 inhibitor nimesulide on breast cancer induced by dimethylbenzoic acid in rats].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2005, Aug-01, Volume: 43, Issue:15

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Mammary Neoplasms, Experimental; Random Allocation; Rats; Rats, Wistar; Sulfonamides

2005
Roles of cyclooxygenase 2 and microsomal prostaglandin E synthase 1 in rat acid reflux oesophagitis.
    Gut, 2006, Volume: 55, Issue:4

    Topics: Animals; Celecoxib; Cell Division; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytosol; Dinoprostone; Epithelial Cells; Esophagitis, Peptic; Esophagus; Immunohistochemistry; Intramolecular Oxidoreductases; Male; Microsomes; Prostaglandin-E Synthases; Pyrazoles; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides

2006
Differential modulation of ovine fetal ACTH secretion by PGHS-1 and PGHS-2.
    Neuroendocrinology, 2006, Volume: 83, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Blood Gas Analysis; Blood Pressure; Brain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Female; Fetus; Heart Rate; Hydrocortisone; Hypotension; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Pregnancy; Pregnancy, Animal; Resveratrol; Sheep; Stilbenes; Sulfonamides

2006
Nimesulide-induced antipyresis in rats involves both cyclooxygenase-dependent and independent mechanisms.
    European journal of pharmacology, 2006, Aug-14, Volume: 543, Issue:1-3

    Topics: Analgesics, Non-Narcotic; Animals; Arachidonic Acid; Body Temperature; Chemokine CCL3; Chemokine CCL4; Corticotropin-Releasing Hormone; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endothelin-1; Fever; Indomethacin; Injections, Intraperitoneal; Injections, Intraventricular; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophage Inflammatory Proteins; Male; Rats; Rats, Wistar; Sulfonamides; Time Factors; Tumor Necrosis Factor-alpha

2006
PGE2 up-regulates EGF-like growth factor biosynthesis in human granulosa cells: new insights into the coordination between PGE2 and LH in ovulation.
    Molecular human reproduction, 2006, Volume: 12, Issue:10

    Topics: Adult; Amphiregulin; Animals; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; EGF Family of Proteins; Epidermal Growth Factor; Epiregulin; Female; Gene Expression Regulation; Glycoproteins; Granulosa Cells; Humans; Intercellular Signaling Peptides and Proteins; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Ovulation; Progesterone; RNA, Messenger; Signal Transduction; Sulfonamides; Time Factors

2006
Cyclooxygenase-2 mediates the sensitizing effects of systemic IL-1-beta on excitotoxic brain lesions in newborn mice.
    Neurobiology of disease, 2007, Volume: 25, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Cerebral Palsy; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation, Enzymologic; Ibotenic Acid; Indomethacin; Interleukin-1beta; Mice; Neurotoxins; Pregnancy; Risk Factors; Sulfonamides

2007
Effect of different cyclooxygenase inhibitors on gastric adaptive cytoprotection induced by 20% ethanol.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:2

    Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytoprotection; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gastric Acid; Gastric Mucosa; Ibuprofen; Irritants; Male; Meloxicam; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyrazoles; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides; Thiazines; Thiazoles

2007
Increased tumor necrosis factor-alpha and prostaglandin E2 concentrations in the cerebrospinal fluid of rats with inflammatory hyperalgesia: the effects of analgesic drugs.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:4

    Topics: Acetaminophen; Administration, Oral; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Drug Combinations; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sulfonamides; Touch; Tramadol; Tumor Necrosis Factor-alpha

2007
Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor.
    Cancer research, 2007, Aug-01, Volume: 67, Issue:15

    Topics: Animals; Carcinoma, Pancreatic Ductal; Cyclooxygenase 2 Inhibitors; Dinoprostone; Disease Models, Animal; Disease Progression; Gene Targeting; Genes, ras; Humans; Immunoenzyme Techniques; Integrases; Mice; Mutation; Pancreatic Neoplasms; Sulfonamides

2007
[Cyclooxygenase (COX)-2 expression in a rat duodenoesophageal reflux model and chemoprevention of adenocarcinoma by the selective COX-2 inhibitor nimesulide].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2007, Volume: 104, Issue:8

    Topics: Adenocarcinoma; Animals; Barrett Esophagus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Disease Models, Animal; Duodenogastric Reflux; Esophageal Neoplasms; Esophagus; Gastric Mucosa; Metaplasia; Rats; RNA, Messenger; Sulfonamides

2007
Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms.
    Cancer letters, 2007, Oct-28, Volume: 256, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Esophageal Neoplasms; Humans; Mitochondrial Membranes; Nitrobenzenes; Sulfonamides; Time Factors

2007
Therapeutic effect of nimesulide on colorectal carcinogenesis in experimental murine ulcerative colitis.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:9

    Topics: Animals; Colitis, Ulcerative; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Sulfonamides

2007
Selective increase of neuronal cyclooxygenase-2 (COX-2) expression in vulnerable brain regions of rats with experimental Wernicke's encephalopathy: effect of nimesulide.
    Metabolic brain disease, 2008, Volume: 23, Issue:2

    Topics: Animals; Brain; Cyclooxygenase 2; Cytoprotection; Dinoprostone; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Immunohistochemistry; Male; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfonamides; Thiamine Deficiency; Up-Regulation; Wernicke Encephalopathy

2008
Effects of a selective cyclooxygenase-2 inhibitor, nimesulide, on the growth of ovarian carcinoma in vivo.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Humans; Mice; Ovarian Neoplasms; Sulfonamides; Xenograft Model Antitumor Assays

2008
Effects of cyclooxygenase-2 non-selective and selective inhibitors on proliferation inhibition and apoptosis induction of esophageal squamous carcinoma cells.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2009, Volume: 22, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Dinoprostone; Esophageal Neoplasms; Humans; In Situ Nick-End Labeling; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides

2009
Cyclooxygenase inhibitors down regulate P-glycoprotein in human colorectal Caco-2 cell line.
    Pharmaceutical research, 2008, Volume: 25, Issue:9

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Caco-2 Cells; Celecoxib; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Naproxen; Neoplasm Proteins; Pyrazoles; Reproducibility of Results; RNA, Messenger; Sulfonamides; Time Factors

2008
Nimesulide inhibits IFN-gamma-induced programmed death-1-ligand 1 surface expression in breast cancer cells by COX-2 and PGE2 independent mechanisms.
    Cancer letters, 2009, Apr-08, Volume: 276, Issue:1

    Topics: Antigens, CD; Antineoplastic Agents; B7-H1 Antigen; Breast Neoplasms; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Female; Flow Cytometry; Gene Expression; Humans; Interferon-gamma; Sulfonamides

2009
Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 113, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Dinoprostone; Disease Models, Animal; Female; Keratinocytes; Keratins; Keratoacanthoma; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; Papilloma; PPAR delta; PPAR-beta; RNA, Messenger; Skin Neoplasms; Sulfonamides; Thiazoles; Time Factors

2010
Similar antineoplastic effects of nimesulide, a selective COX-2 inhibitor, and prostaglandin E1 on B16-F10 murine melanoma cells.
    Melanoma research, 2010, Volume: 20, Issue:4

    Topics: Alprostadil; Animals; Antineoplastic Agents; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Melanins; Melanoma, Experimental; Sulfonamides; Transglutaminases

2010
Cox-2 inhibitors induce early c-Myc downregulation and lead to expression of differentiation markers in leukemia cells.
    Cell cycle (Georgetown, Tex.), 2011, Sep-01, Volume: 10, Issue:17

    Topics: Antigens, Differentiation; Apoptosis; Biomarkers; Celecoxib; Cell Differentiation; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Gene Expression Regulation, Leukemic; Humans; Interphase; Jurkat Cells; K562 Cells; Nitrobenzenes; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Pyrazoles; Sulfonamides; U937 Cells; Up-Regulation

2011
Airway remodeling in murine asthma correlates with a defect in PGE2 synthesis by lung fibroblasts.
    American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 301, Issue:5

    Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchi; Cell Proliferation; Chronic Disease; Collagen; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Disease Models, Animal; Down-Regulation; Female; Fibroblasts; Histocytochemistry; Humans; Inflammation; Intramolecular Oxidoreductases; Mice; Prostaglandin-E Synthases; Pulmonary Fibrosis; Real-Time Polymerase Chain Reaction; Sulfonamides

2011
Prostaglandins mediate the fetal pulmonary response to intrauterine inflammation.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Apr-01, Volume: 302, Issue:7

    Topics: Amniotic Fluid; Animals; Chorioamnionitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Interleukin-1beta; Interleukin-8; Lipopolysaccharides; Lung; Lung Compliance; Pneumonia; Pregnancy; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Random Allocation; RNA, Messenger; Sheep; Sulfonamides; Uterus

2012
Retinoic acid increases hypoxia-inducible factor-1α through intracrine prostaglandin E(2) signaling in human renal proximal tubular cells HK-2.
    Biochimica et biophysica acta, 2012, Volume: 1821, Issue:4

    Topics: Blotting, Western; Cell Hypoxia; Cell Line; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-1beta; Intracellular Space; Kidney Tubules, Proximal; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfonamides; Tretinoin; Up-Regulation; Vascular Endothelial Growth Factor A

2012
Prostaglandin synthases influence thyroid follicular cell proliferation but not carcinogenesis in rats initiated with N-bis(2-hydroxypropyl)nitrosamine.
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 127, Issue:2

    Topics: Adenocarcinoma, Follicular; Animals; Antithyroid Agents; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Immunohistochemistry; Indomethacin; Intramolecular Oxidoreductases; Male; Nitrosamines; Organ Size; Precancerous Conditions; Prostaglandin-E Synthases; Rats; Rats, Inbred F344; Sulfadimethoxine; Sulfonamides; Thyroid Gland; Thyroid Hormones; Thyroid Neoplasms; Time Factors

2012
Prostaglandin E2 stimulates estradiol synthesis in the cerebellum postnatally with associated effects on Purkinje neuron dendritic arbor and electrophysiological properties.
    Endocrinology, 2012, Volume: 153, Issue:11

    Topics: Action Potentials; Animals; Aromatase; Cells, Cultured; Cerebellum; Cyclooxygenase Inhibitors; Dendrites; Dendritic Spines; Dinoprostone; Estradiol; Female; Indomethacin; Male; Microfilament Proteins; Nerve Tissue Proteins; Purkinje Cells; Rats; Rats, Sprague-Dawley; Sulfonamides

2012
Prostaglandin ethanolamides attenuate damage in a human explant colitis model.
    Prostaglandins & other lipid mediators, 2013, Volume: 100-101

    Topics: Adult; Amides; Arachidonic Acids; Bimatoprost; Cloprostenol; Colitis; Colon, Sigmoid; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Endocannabinoids; Female; Humans; Immunohistochemistry; Interleukin-1beta; Male; Middle Aged; Oxazoles; Polyunsaturated Alkamides; Receptors, Prostaglandin; Sulfonamides; Tissue Culture Techniques; Tumor Necrosis Factor-alpha; Young Adult

2013
Cyclooxygenase-2, prostaglandin E2 glycerol ester and nitric oxide are involved in muscarine-induced presynaptic enhancement at the vertebrate neuromuscular junction.
    The Journal of physiology, 2013, Oct-01, Volume: 591, Issue:19

    Topics: Animals; Arachidonic Acids; Benzoates; Capsaicin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Endocannabinoids; Glycerides; Imidazoles; Lizards; Miniature Postsynaptic Potentials; Muscarine; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Schwann Cells; Sulfonamides; Thiophenes; Xanthones

2013
Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells.
    Molecules (Basel, Switzerland), 2013, Aug-22, Volume: 18, Issue:9

    Topics: Coculture Techniques; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Enzyme Induction; HL-60 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon gamma Receptor; Interferon-gamma; Kynurenine; Leukemia, Myeloid, Acute; Receptors, Interferon; Sulfonamides; T-Lymphocytes, Regulatory

2013
Adenosine signalling mediates the anti-inflammatory effects of the COX-2 inhibitor nimesulide.
    Biochemical pharmacology, 2016, 07-15, Volume: 112

    Topics: 5'-Nucleotidase; Adenosine; Animals; Anti-Inflammatory Agents; Cell Line; Cyclooxygenase 2 Inhibitors; Dinoprostone; Edema; Macrophages; Male; Rats, Wistar; Receptor, Adenosine A2A; Signal Transduction; Sulfonamides

2016
Gamma-Terpinene Modulation of LPS-Stimulated Macrophages is Dependent on the PGE2/IL-10 Axis.
    Planta medica, 2016, Volume: 82, Issue:15

    Topics: Animals; Cells, Cultured; Cyclohexane Monoterpenes; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Interleukin-10; Interleukin-12; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice, Inbred BALB C; Monoterpenes; Sulfonamides

2016
Nimesulide inhibits pathogenic fungi: PGE2-dependent mechanisms.
    Folia microbiologica, 2017, Volume: 62, Issue:2

    Topics: Antifungal Agents; Arthrodermataceae; Aspergillus fumigatus; Cryptococcus neoformans; Dinoprostone; Microbial Sensitivity Tests; Sulfonamides; Trichophyton

2017
IDO, COX and iNOS have an important role in the proliferation of Neospora caninum in neuron/glia co-cultures.
    Veterinary parasitology, 2019, Volume: 266

    Topics: Animals; Cells, Cultured; Coculture Techniques; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Host-Parasite Interactions; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indomethacin; Interleukin-10; Neospora; Neuroglia; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Rats; Sulfonamides; Tryptophan; Tumor Necrosis Factor-alpha

2019
Depletion of tumor-associated macrophages inhibits lung cancer growth and enhances the antitumor effect of cisplatin.
    Cancer science, 2023, Volume: 114, Issue:3

    Topics: Animals; Cell Line, Tumor; Cisplatin; Dinoprostone; Lung Neoplasms; Mice; Tumor Microenvironment; Tumor-Associated Macrophages

2023