nimesulide and aspirin

nimesulide has been researched along with aspirin in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.94)	18.7374
1990's	16 (23.53)	18.2507
2000's	40 (58.82)	29.6817
2010's	10 (14.71)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Backlund, A; Bohlin, L; Gottfries, J; Larsson, J	1
Bauer, R; Goeters, S; Hempel, B; Imming, P; Krause, E; Lohmann, K; Ramadan, M; Watzer, B	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Bernasconi, P; Massera, E	1
Magni, E; Massera, E; Reiner, M	1
Casolaro, V; de Paulis, A; Guidi, G; Marino, O; Marone, G; Meliota, S; Patella, V	1
Bianco, S; Petrigni, G; Pieroni, MG; Refini, RM; Robuschi, M; Scuri, M; Sestini, PS; Vaghi, A	1
Barberi, I; Macchia, A; Nava, ML; Scaricabarozzi, I; Spata, N	1
Cappella, L; Cavazzuti, GB; Guerra, A; Laudizi, L	1
Hernández-Tobías, A; Piña, E; Saldaña-Balmori, Y; Zentella de Piña, M	1
Andri, G; Andri, L; Betteli, C; Givanni, S; Mezzelani, P; Scaricabarozzi, I; Senna, G	1
Albano, M; Andri, G; Andri, L; Dama, AR; Fregonese, L; Passalacqua, G; Senna, GE	1
Ciccarelli, A; de Crescenzo, G; de Paulis, A; Marinò, D; Marinò, I; Marone, G	1
Gilroy, DW; Tomlinson, A; Willoughby, DA	2
Alam, CA; Brown, JR; Colville-Nash, PR; Freemantle, CN; Papworth, JL; Seed, MP; Somerville, KW; Willoughby, DA	1
Harada, Y; Hatanaka, K; Kawamura, M; Ogino, K; Ogino, M; Ohno, T; Saito, M; Yang, Q	1
Asero, R	3
Giuliano, F; Warner, TD	1
Chiang, N; Clària, J; Gaya, J; Pueyo, G; Romano, M; Serhan, CN; Titos, E	1
Bavbek, S; Celik, G; Demirel, YS; Ediger, D; Misirligil, Z; Mungan, D	1
Mitchell, JA; Pepper, JR; Stanford, SJ	1
Belton, O; Byrne, D; Fitzgerald, DJ; Kearney, D; Leahy, A	1
Burgaud, JL; Ea-Kim, L; Ghanam, K; Javellaud, J; Lavagna, C; Oudart, N	1
Dunn, AJ; Swiergiel, AH	1
Ballerio, R; Bianchib, M; Buccellati, C; Sala, A	1
Cabrera, WK; De Franco, M; Gallois, V; Ibañez, OM; Maria, DA; Pizzocaro, KF; Ribeiro, OG; Seman, M; Siqueira, M; Starobinas, N	1
Kankuri, E; Korpela, R; Moilanen, E; Paakkari, I; Vaali, K; Vapaatalo, H	1
Bhatnagar, SK; Chandra, J	1
Di Paola, R; Ferrannini, A; Napoli, G; Nettis, E; Tursi, A	1
de Zentella, PM; Pimentel, L; Piña, E; Piña-Zentella, G; Vázquez-Meza, H	1
Burde, T; Rimon, G	1
Del Soldato, P; Gray, PA; Mitchell, JA; Parikh, A; Scadding, GK; Vojnovic, I; Warner, TD	1
Karunakar, N; Krishna, DR; Prabhakar, MC	1
Bennett, P; Pan, H; Sawdy, R; Sullivan, M	1
Byrne, A; Cox, D; Crean, P; Fitzgerald, DJ; Kearney, D	1
Frishman, WH	1
Bavbek, S; Celik, G; Misirligil, Z; Mungan, D; Ozer, F	1
de Champlain, J; Laplante, MA; Wu, R	1
Adams, E; Dehouck, P; Haghedooren, E; Hoogmartens, J; Kóczián, K; Kovács, Z; Noszál, B; Visky, D	1
Colosimo, M; De Caro, E; De Sarro, G; Gallelli, L; Iannacchero, R; Peltrone, F	1
Ho, B; Kulmacz, RJ; Liu, W; Rogge, CE; Tsai, AL	1
Bjarnason, I; Bjornsson, E; Maiden, L; Premchand, P; Sherwood, R; Smale, S; Takeuchi, K; Thjodleifsson, B	1
Kaushal, N; Sanyal, SN	1
Ballmer-Weber, BK; Hofbauer, G; Roll, A; Schmid-Grendelmeier, P; Wüthrich, B	1
Błaszczyk, J; Fijałkowski, P; Kopff, A; Kopff, M; Kowalczyk, E	1
Agundis, C; Pardo, JP; Pereyra, MA; Piña, E; Vázquez-Meza, H; Villalobos-Molina, R; Zentella de Piña, M	1
Aldasoro, M; Cortina, B; Mauricio, MD; Medina, P; Novella, S; Segarra, G; Serna, E; Vila, JM	1
Kopff, A; Kopff, M; Kowalczyk, E	2
Aldasoro, M; Cortina, B; Flor, B; Lluch, S; Mauricio, MD; Medina, P; Segarra, G; Serna, E; Vila, JM	1
Jia, JD; Li, P; Liu, X; You, H; Yu, ZL; Zhang, ST	1
Cho, CH; Li, P; Liu, X; Wu, YD; Xu, CM; Yu, ZL; Zhang, ST	1
Han, JA; Kim, SR; Lee, ME; Park, JH; Park, JS; Park, SC	1
Cheng, Y; Guo, SX	1
Kankaanranta, H; Kerola, M; Kosonen, O; Moilanen, E; Sarna, S; Vuolteenaho, K	1
Lee, JY; Sidhu, RS; Smith, WL; Yuan, C	1
Bayram, D; Cicek, E; Karabacak, HI; Oncu, M; Ozer, MK; Yesilot, S	1
Derry, S; McQuay, HJ; Moll, R; Moore, RA	1
Gołab, J; Jakubowska-Mućka, A; Lasek, W; Sieńko, J; Switaj, T	1

Reviews

6 review(s) available for nimesulide and aspirin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Efficacy and tolerability of nimesulide in asthmatic patients intolerant to aspirin. Drugs, 1993, Volume: 46 Suppl 1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Clinical Trials as Topic; Contraindications; Drug Interactions; Humans; Sulfonamides	1993
Nimesulide in the treatment of patients intolerant of aspirin and other NSAIDs. Drug safety, 1996, Volume: 14, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans; Rhinitis; Sulfonamides	1996
Antipyretics in children. Indian journal of pediatrics, 2002, Volume: 69, Issue:1 Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Child; Cyclooxygenase Inhibitors; Fever; Humans; Ibuprofen; Mefenamic Acid; Sulfonamides	2002
[Research advance on pediatric antipyretic]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2008, Volume: 10, Issue:6 Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Fever; Humans; Ibuprofen; Sulfonamides	2008
Single dose oral mefenamic acid for acute postoperative pain in adults. The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3 Topics: Acute Disease; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Mefenamic Acid; Pain, Postoperative; Randomized Controlled Trials as Topic; Sulfonamides; Tolmetin	2011

Trials

14 trial(s) available for nimesulide and aspirin

Article	Year
Nimesulide in the treatment of fever: a double-blind, crossover clinical trial. The Journal of international medical research, 1984, Volume: 12, Issue:2 Topics: Adult; Aged; Aspirin; Body Temperature; Clinical Trials as Topic; Dipyrone; Double-Blind Method; Female; Fever; Humans; Male; Middle Aged; Pulse; Sulfonamides; Time Factors	1984
Double-blind evaluation of nimesulide vs lysine-aspirin in the treatment of paediatric acute respiratory tract infections. Drugs, 1993, Volume: 46 Suppl 1 Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Double-Blind Method; Female; Humans; Lysine; Male; Respiratory Tract Infections; Sulfonamides	1993
Efficacy and tolerability of nimesulide and lysine-acetylsalicylate in the treatment of paediatric acute upper respiratory tract inflammation. Drugs, 1993, Volume: 46 Suppl 1 Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Female; Humans; Lysine; Male; Respiratory Tract Infections; Single-Blind Method; Sulfonamides	1993
Tolerability of nimesulide in aspirin-sensitive patients. Annals of allergy, 1994, Volume: 72, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Single-Blind Method; Sulfonamides	1994
Aspirin and paracetamol tolerance in patients with nimesulide-induced urticaria. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1998, Volume: 81, Issue:3 Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Drug Tolerance; Female; Humans; Immune Tolerance; Male; Middle Aged; Sulfonamides; Urticaria	1998
The use of nimesulide in patients with acetylsalicylic acid and nonsteroidal anti-inflammatory drug intolerance. The Journal of asthma : official journal of the Association for the Care of Asthma, 1999, Volume: 36, Issue:8 Topics: Administration, Oral; Adult; Aged; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Prevalence; Rhinitis; Single-Blind Method; Skin Tests; Sulfonamides; Urticaria	1999
Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. Circulation, 2000, Aug-22, Volume: 102, Issue:8 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Epoprostenol; F2-Isoprostanes; Female; Humans; Isoenzymes; Macrophages; Male; Membrane Proteins; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane A2; Thromboxane B2	2000
Benzydamine: an alternative nonsteroidal anti-inflammatory drug in patients with nimesulide-induced urticaria. Allergy, 2002, Volume: 57, Issue:5 Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzydamine; Dipyrone; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Humans; Italy; Male; Middle Aged; Pyrazolones; Single-Blind Method; Sulfonamides; Urticaria	2002
Optimal suppression of thromboxane A(2) formation by aspirin during percutaneous transluminal coronary angioplasty: no additional effect of a selective cyclooxygenase-2 inhibitor. Journal of the American College of Cardiology, 2004, Feb-18, Volume: 43, Issue:4 Topics: Angioplasty, Balloon, Coronary; Aspirin; Biphenyl Compounds; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprost; Epoprostenol; Female; Humans; Isoenzymes; Male; Membrane Proteins; Middle Aged; Peroxidases; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prostaglandin-Endoperoxide Synthases; Pyrrolidines; Sulfonamides; Thromboxane A2	2004
Safety of selective COX-2 inhibitors in aspirin/nonsteroidal anti-inflammatory drug-intolerant patients: comparison of nimesulide, meloxicam, and rofecoxib. The Journal of asthma : official journal of the Association for the Care of Asthma, 2004, Volume: 41, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Female; Humans; Immunologic Tests; Lactones; Male; Meloxicam; Middle Aged; Single-Blind Method; Sulfonamides; Sulfones; Thiazines; Thiazoles; Treatment Outcome; Urticaria	2004
Oral aspirin challenges in patients with a history of intolerance to single non-steroidal anti-inflammatory drugs. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:6 Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Cyclooxygenase Inhibitors; Drug Evaluation; Female; Humans; Lactones; Male; Middle Aged; ortho-Aminobenzoates; Recurrence; Single-Blind Method; Sulfonamides; Sulfones; Tramadol; Urticaria	2005
Use of ketoprofen oral challenges to detect cross-reactors among patients with a history of aspirin-induced urticaria. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:2 Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross Reactions; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Female; Humans; Ketoprofen; Lactones; Male; Middle Aged; Placebos; Sulfonamides; Sulfones; Tramadol; Urticaria	2006
Tolerance to celecoxib in patients with a history of adverse reactions to nonsteroidal anti-inflammatory drugs. Swiss medical weekly, 2006, Oct-28, Volume: 136, Issue:43-44 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Prospective Studies; Pyrazoles; Single-Blind Method; Sulfonamides	2006
Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo. Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:1 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Ibuprofen; Male; Nabumetone; Sulfonamides; Thromboxane B2	2009

Other Studies

48 other study(ies) available for nimesulide and aspirin

Article	Year
Expanding the ChemGPS chemical space with natural products. Journal of natural products, 2005, Volume: 68, Issue:7 Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship	2005
Chamazulene carboxylic acid and matricin: a natural profen and its natural prodrug, identified through similarity to synthetic drug substances. Journal of natural products, 2006, Volume: 69, Issue:7 Topics: Achillea; Anti-Inflammatory Agents, Non-Steroidal; Azulenes; Carboxylic Acids; Cycloheptanes; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Germany; Lactones; Matricaria; Molecular Structure; Pharmaceutical Preparations; Prodrugs; Sesquiterpenes; Sesquiterpenes, Guaiane	2006
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Evaluation of a new pharmaceutical form of nimesulide for the treatment of influenza. Drugs under experimental and clinical research, 1985, Volume: 11, Issue:10 Topics: Adolescent; Adult; Anti-Inflammatory Agents; Ascorbic Acid; Aspirin; Body Temperature; Female; Humans; Influenza, Human; Male; Middle Aged; Sulfonamides	1985
Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3 Topics: Adolescent; Adult; Alprostadil; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Bryostatins; Calcimycin; Colforsin; Complement C5a; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Lactones; Leukotriene C4; Lung; Macrolides; Mast Cells; Middle Aged; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandin D2; Skin; Sulfonamides; Tetradecanoylphorbol Acetate	1993
Nonsteroidal antiinflammatory drugs lower ethanol-mediated liver increase in lipids and thiobarbituric acid reactive substances. Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:6 Topics: Alcoholic Intoxication; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dipyrone; Ethanol; Fatty Liver, Alcoholic; Free Radicals; Lipid Metabolism; Lipid Peroxidation; Male; Metabolic Clearance Rate; Naproxen; Rats; Rats, Wistar; Sulfonamides; Thiobarbiturates; Triglycerides	1993
Human synovial mast cells. II. Heterogeneity of the pharmacologic effects of antiinflammatory and immunosuppressive drugs. Arthritis and rheumatism, 1997, Volume: 40, Issue:3 Topics: Adenosine; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chymases; Cyclosporine; Diclofenac; Histamine Release; Humans; Immunoglobulin E; Immunosuppressive Agents; Leukotriene C4; Mast Cells; Methotrexate; Middle Aged; Polyenes; Prostaglandins D; Rheumatic Diseases; Serine Endopeptidases; Sirolimus; Substance P; Sulfonamides; Synovial Membrane; Tacrolimus; Tryptases	1997
Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:2 Topics: Air; Air Sacs; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Croton Oil; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Induction; Freund's Adjuvant; Granuloma; Isoenzymes; Membrane Proteins; Mice; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides	1998
Apoptosis induction and inhibition of colon-26 tumour growth and angiogenesis: findings on COX-1 and COX-2 inhibitors in vitro & in vivo and topical diclofenac in hyaluronan. Advances in experimental medicine and biology, 1997, Volume: 433 Topics: Administration, Topical; Animals; Apoptosis; Aspirin; Cell Division; Cell Survival; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Carriers; Female; Hyaluronic Acid; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred BALB C; Necrosis; Neovascularization, Pathologic; Piroxicam; Prostaglandin-Endoperoxide Synthases; Sulfonamides	1997
Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat. Prostaglandins & other lipid mediators, 1998, Volume: 55, Issue:5-6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gastric Juice; Indomethacin; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Pleurisy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sulfonamides; Thromboxane B2	1998
Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Piroxicam; Pleural Effusion; Pleurisy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides	1998
Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs. British journal of pharmacology, 1999, Volume: 126, Issue:8 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Blood Pressure; Carcinoma; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salicylates; Substrate Specificity; Sulfonamides; Sulindac; Thromboxane B2; Tumor Cells, Cultured	1999
Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). The American journal of physiology, 1999, Volume: 277, Issue:5 Topics: Animals; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Isoenzymes; Lipoxins; Liver; Male; Membrane Proteins; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Thromboxane B2	1999
Cyclooxygenase-2 regulates granulocyte-macrophage colony-stimulating factor, but not interleukin-8, production by human vascular cells: role of cAMP. Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arteriosclerosis; Aspirin; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indans; Indomethacin; Interleukin-1; Interleukin-8; Isoenzymes; Mammary Arteries; Meloxicam; Membrane Proteins; Muscle, Smooth, Vascular; Neutrophils; Prostaglandin-Endoperoxide Synthases; Saphenous Vein; Sulfonamides; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha	2000
Involvement of cyclooxygenase 2 in the protective effect of 17beta-estradiol on hypercholesterolemic rabbit aorta. Biochemical and biophysical research communications, 2000, Aug-28, Volume: 275, Issue:2 Topics: Acetylcholine; Adenine; Animals; Aorta; Aspirin; Cholesterol; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Estradiol; Hypercholesterolemia; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Prostaglandin-Endoperoxide Synthases; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Triglycerides	2000
The role of cyclooxygenases in endotoxin- and interleukin-1-induced hypophagia. Brain, behavior, and immunity, 2000, Volume: 14, Issue:3 Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Drinking; Endotoxins; Feeding and Eating Disorders; Indomethacin; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Lipopolysaccharides; Male; Mice; Milk; Nitrobenzenes; Piroxicam; Prostaglandin-Endoperoxide Synthases; Sialoglycoproteins; Sulfonamides	2000
Tramadol anti-inflammatory activity is not related to a direct inhibitory action on prostaglandin endoperoxide synthases. European journal of pain (London, England), 2000, Volume: 4, Issue:4 Topics: Analgesics, Opioid; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; In Vitro Techniques; Isoenzymes; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2; Tramadol	2000
Resistance to melanoma metastases in mice selected for high acute inflammatory response. Carcinogenesis, 2001, Volume: 22, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Neoplasm; Antigens, Neoplasm; Aspirin; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Genetic Predisposition to Disease; Melanoma; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Mutant Strains; Monitoring, Immunologic; Neoplasm Transplantation; Skin Neoplasms; Sulfonamides; Transplantation, Heterologous; Tumor Cells, Cultured	2001
Effects of a COX-2 preferential agent nimesulide on TNBS-induced acute inflammation in the gut. Inflammation, 2001, Volume: 25, Issue:5 Topics: Acute Disease; Animals; Aspirin; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Disease Models, Animal; Drug Evaluation, Preclinical; Indomethacin; Inflammation; Inflammatory Bowel Diseases; Isoenzymes; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides; Trinitrobenzenesulfonic Acid	2001
Non-steroidal anti-inflammatory drugs inhibit epinephrine- and cAMP-mediated lipolysis in isolated rat adipocytes. The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:4 Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bucladesine; Dihydroalprenolol; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Ethanol; Glycerol; Guinea Pigs; Lipolysis; Male; Naproxen; Piroxicam; Rats; Rats, Wistar; Sulfonamides; Thiobarbituric Acid Reactive Substances; Triglycerides	2002
On the interaction of specific prostaglandin H synthase-2 inhibitors with prostaglandin H synthase-1. European journal of pharmacology, 2002, Oct-25, Volume: 453, Issue:2-3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Binding, Competitive; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ibuprofen; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Sulfonamides	2002
Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors. British journal of pharmacology, 2002, Volume: 137, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Benzene Derivatives; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Furans; Humans; Indomethacin; Ionophores; Isoenzymes; Leukotrienes; Lipopolysaccharides; Lipoxygenase; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2	2002
Determination of antioxidant activity of some drugs using high-pressure liquid chromatography. Arzneimittel-Forschung, 2003, Volume: 53, Issue:4 Topics: Antioxidants; Ascorbic Acid; Aspirin; Biphenyl Compounds; Chromatography, High Pressure Liquid; Dapsone; Free Radicals; Methyldopa; Picrates; Quercetin; Rifampin; Spectrophotometry, Ultraviolet; Sulfonamides	2003
Effect of selective vs. non-selective cyclo-oxygenase inhibitors on fetal membrane prostaglandin synthesis. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2003, Volume: 23, Issue:3 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Extraembryonic Membranes; Female; Furans; Humans; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Meloxicam; Membrane Proteins; Pregnancy; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thiazines; Thiazoles	2003
Cyclooxygenase inhibition in patients with coronary artery disease. Journal of the American College of Cardiology, 2004, Feb-18, Volume: 43, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Artery Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Humans; Isoenzymes; Membrane Proteins; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane A2	2004
Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:6 Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiomegaly; Cells, Cultured; Cyclooxygenase Inhibitors; Hypertension; Lactones; Male; Myocardium; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulfones	2005
Facilitated column selection in pharmaceutical analyses using a simple column classification system. Journal of chromatography. A, 2006, Jan-06, Volume: 1101, Issue:1-2 Topics: Aspirin; Chloramphenicol; Chromatography, Liquid; Clindamycin; Dihydrostreptomycin Sulfate; Penicillin V; Pharmaceutical Preparations; Pyrrolidines; Sensitivity and Specificity; Sulfonamides	2006
A questionnaire-based study on prevalence and treatment of headache in young children. The journal of headache and pain, 2005, Volume: 6, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Female; Headache; Humans; Incidence; Male; Prevalence; Sulfonamides; Surveys and Questionnaires	2005
Role of Tyr348 in Tyr385 radical dynamics and cyclooxygenase inhibitor interactions in prostaglandin H synthase-2. Biochemistry, 2006, Jan-17, Volume: 45, Issue:2 Topics: Amino Acid Substitution; Aspirin; Binding Sites; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydrogen Bonding; Isoenzymes; Mutation; Peroxidases; Phenylalanine; Protein Conformation; Substrate Specificity; Sulfonamides; Thermodynamics; Tyrosine	2006
Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006, Volume: 4, Issue:2 Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Colitis, Ulcerative; Crohn Disease; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Indomethacin; Inflammatory Bowel Diseases; Male; Middle Aged; Nabumetone; Naproxen; Prevalence; Recurrence; Sulfonamides	2006
Modulations in the intestinal disaccharide hydrolases and membrane dynamics: effect of non-steroidal anti-inflammatory drugs aspirin and nimesulide. Molecular and cellular biochemistry, 2007, Volume: 294, Issue:1-2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disaccharides; Female; Hydrolases; Intestinal Mucosa; Microvilli; Random Allocation; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Sulfonamides	2007
[The influence of selected nonsteroidal anti-inflammatory drugs on antioxidative enzymes activity]. Polskie Archiwum Medycyny Wewnetrznej, 2006, Volume: 115, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Catalase; Cyclooxygenase Inhibitors; Diclofenac; Glutathione Peroxidase; Instillation, Drug; Male; Oxidants; Rats; Rats, Wistar; Sulfonamides; Superoxide Dismutase	2006
Inhibition of cAMP-dependent protein kinase A: a novel cyclo-oxygenase-independent effect of non-steroidal anti-inflammatory drugs in adipocytes. Autonomic & autacoid pharmacology, 2007, Volume: 27, Issue:2 Topics: Adipocytes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Male; Myocardium; Naproxen; Piroxicam; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Rats; Rats, Wistar; Sterol Esterase; Sulfonamides	2007
Aspirin and COX-2 inhibitor nimesulide potentiate adrenergic contractions of human gastroepiploic artery. American journal of hypertension, 2007, Volume: 20, Issue:5 Topics: Acetylcholine; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Electric Stimulation; Female; Gastroepiploic Artery; Humans; In Vitro Techniques; Male; Membrane Proteins; Prostaglandins; Pyrazoles; Sulfonamides	2007
[The effect of nonsteroidal anti-inflammatory drugs on oxidative/antioxidative balance]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2007, Volume: 23, Issue:135 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Female; Male; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfonamides	2007
Effects of aspirin, nimesulide, and SC-560 on vasopressin-induced contraction of human gastroepiploic artery and saphenous vein. Critical care medicine, 2008, Volume: 36, Issue:1 Topics: Aged; Aged, 80 and over; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Gastroepiploic Artery; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Pyrazoles; Saphenous Vein; Sulfonamides; Vasopressins	2008
COX-2 mRNA expression in esophageal squamous cell carcinoma (ESCC) and effect by NSAID. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2008, Volume: 21, Issue:1 Topics: Aspirin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Esophageal Neoplasms; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides	2008
Effects of cyclooxygenase-2 non-selective and selective inhibitors on proliferation inhibition and apoptosis induction of esophageal squamous carcinoma cells. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2009, Volume: 22, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Dinoprostone; Esophageal Neoplasms; Humans; In Situ Nick-End Labeling; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides	2009
[The influence of nonsteroidal anti-inflammatory drugs on deaminase adenosine activity]. Polskie Archiwum Medycyny Wewnetrznej, 2006, Volume: 116, Issue:3 Topics: Adenosine Deaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Erythrocytes; Female; Isoenzymes; Male; Rats; Rats, Wistar; Sulfonamides	2006
Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner. Mechanisms of ageing and development, 2008, Volume: 129, Issue:12 Topics: Aspirin; Caveolin 1; Celecoxib; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fibroblasts; Flurbiprofen; Humans; Ibuprofen; Kinetics; Models, Biological; NF-kappa B; Nitrobenzenes; Pyrazoles; Reactive Oxygen Species; Skin; Skin Aging; Sulfonamides; Tumor Suppressor Protein p53	2008
Comparison of cyclooxygenase-1 crystal structures: cross-talk between monomers comprising cyclooxygenase-1 homodimers. Biochemistry, 2010, Aug-24, Volume: 49, Issue:33 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catalytic Domain; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Diclofenac; Flurbiprofen; Ligands; Models, Molecular; Protein Binding; Protein Conformation; Protein Multimerization; Sheep; Sulfonamides	2010
Effects of aspirin and nimesulide on tissue damage in diabetic rats. Cytokine, 2010, Volume: 52, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Streptozocin; Sulfonamides; Superoxide Dismutase	2010
[Antitumor effects of sulindac in ovarian cell cultures]. Ginekologia polska, 2011, Volume: 82, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Cell Cycle; Cell Size; Cell Survival; Colorimetry; Female; Humans; Lactones; Ovarian Neoplasms; Sulfonamides; Sulfones; Sulindac; Tumor Cells, Cultured	2011