nimesulide and arachidonic acid

nimesulide has been researched along with arachidonic acid in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (29.41)18.2507
2000's10 (58.82)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Magni, E1
Bennett, A; Bishai, PM; Tavares, IA1
Tool, AT; Verhoeven, AJ1
Crews, BC; Kalgutkar, AS; Marnett, LJ1
Furukawa, M; Nakatsugi, S; Sugimoto, N1
González, JD; Llinás, MT; Rivera, J; Rodríguez, F; Salazar, FJ1
Burde, T; Rimon, G1
Backhouse, N; Bórquez, J; Delporte, C; Loyola, A; Salinas, P; San-Martín, A1
Bruemmer, D; Duffy, JP; Eibl, G; Hines, OJ; Law, RE; Okada, Y; Reber, HA1
Kalgutkar, AS; Kiefer, JR; Kozak, KR; Kurumbail, RG; Marnett, LJ; Pawlitz, JL; Prusakiewicz, JJ; Rowlinson, SW; Stallings, WC1
Kondo, M; Nagai, A; Nakata, J; Nohara, M; Takemiya, T; Tamaoki, J; Yamagata, K1
Aguirre, MC; Alegría, S; Backhouse, N; Cassels, BK; Delporte, C; Erazo, S; Letelier, ME; Negrete, R; Silva, X1
Souza, GE; Werner, MF; Zampronio, AR1
Baber, SR; Hyman, AL; Kadowitz, PJ; Nazim, MM; Nossaman, BD; Waldron, PR1
Barrett, TD; Hong, TT; Huang, J; Lucchesi, BR1
Kulmacz, RJ; Liu, W; Poole, EM; Ulrich, CM1
Järving, R; Kukk, K; Samel, N1

Reviews

1 review(s) available for nimesulide and arachidonic acid

ArticleYear
The effect of nimesulide on prostanoid formation.
    Drugs, 1993, Volume: 46 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Humans; Kidney; Lung; Prostaglandins; Sulfonamides

1993

Other Studies

16 other study(ies) available for nimesulide and arachidonic acid

ArticleYear
Activity of nimesulide on constitutive and inducible cyclooxygenases.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:10

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase Inhibitors; Enzyme Induction; Gastric Mucosa; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Radioimmunoassay; Sheep; Sulfonamides

1995
Inhibition of the production of platelet activating factor and of leukotriene B4 in activated neutrophils by nimesulide due to an elevation of intracellular cyclic adenosine monophosphate.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin B; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoquinolines; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Sulfonamides; Zymosan

1995
Kinetics of the interaction of nonsteroidal antiinflammatory drugs with prostaglandin endoperoxide synthase-1 studied by limited proteolysis.
    Biochemistry, 1996, Jul-16, Volume: 35, Issue:28

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase Inhibitors; Hemin; Ibuprofen; Kinetics; Molecular Structure; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostanoic Acids; Protein Binding; Protein Conformation; Sulfonamides; Thiazoles; Trypsin

1996
Effects of non-steroidal anti-inflammatory drugs on prostaglandin E2 production by cyclooxygenase-2 from endogenous and exogenous arachidonic acid in rat peritoneal macrophages stimulated with lipopolysaccharide.
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 55, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Ibuprofen; Indomethacin; Isoenzymes; Lipopolysaccharides; Macrophages, Peritoneal; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides

1996
Renal changes induced by a cyclooxygenase-2 inhibitor during normal and low sodium intake.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:2

    Topics: Animals; Arachidonic Acid; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Isoenzymes; Kidney; Lithium; Male; Meclofenamic Acid; Platelet Aggregation; Platelet Count; Prostaglandin-Endoperoxide Synthases; Renal Circulation; Sodium, Dietary; Sulfonamides; Urodynamics

2000
On the interaction of specific prostaglandin H synthase-2 inhibitors with prostaglandin H synthase-1.
    European journal of pharmacology, 2002, Oct-25, Volume: 453, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Binding, Competitive; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ibuprofen; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Sulfonamides

2002
Pharmaco-toxicological study of diterpenoids.
    Bioorganic & medicinal chemistry, 2003, Apr-03, Volume: 11, Issue:7

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Apiaceae; Arachidonic Acid; Chile; Diterpenes; Dose-Response Relationship, Drug; Edema; Female; Indicators and Reagents; Indomethacin; Lipoxygenase Inhibitors; Male; Mice; Molecular Conformation; Naproxen; Pain Measurement; Plants, Medicinal; Structure-Activity Relationship; Sulfonamides; Tetradecanoylphorbol Acetate

2003
PGE(2) is generated by specific COX-2 activity and increases VEGF production in COX-2-expressing human pancreatic cancer cells.
    Biochemical and biophysical research communications, 2003, Jul-11, Volume: 306, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Arachidonic Acid; Blotting, Western; Cell Movement; Cells, Cultured; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Humans; Intercellular Signaling Peptides and Proteins; Isoenzymes; Lymphokines; Membrane Proteins; Models, Biological; Pancreatic Neoplasms; Plasmids; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Time Factors; Transfection; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
A novel mechanism of cyclooxygenase-2 inhibition involving interactions with Ser-530 and Tyr-385.
    The Journal of biological chemistry, 2003, Nov-14, Volume: 278, Issue:46

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arginine; Binding, Competitive; Cell Line; Crystallography, X-Ray; Cyclooxygenase 2; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Insecta; Isoenzymes; Mice; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Piroxicam; Prostaglandin-Endoperoxide Synthases; Protein Binding; Serine; Sulfonamides; Time Factors; Tyrosine

2003
Augmentation of allergic inflammation in the airways of cyclooxygenase-2-deficient mice.
    Respirology (Carlton, Vic.), 2005, Volume: 10, Issue:2

    Topics: Animals; Arachidonic Acid; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cysteine; Dinoprostone; Female; Immunoglobulin E; Inflammation; Interleukin-13; Leukotrienes; Lung; Male; Metaplasia; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Sulfonamides

2005
Topical anti-inflammatory activity of 2alpha-hydroxy pentacyclic triterpene acids from the leaves of Ugni molinae.
    Bioorganic & medicinal chemistry, 2006, Aug-15, Volume: 14, Issue:16

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Betulinic Acid; Dose-Response Relationship, Drug; Indomethacin; Male; Mice; Myrtaceae; Otitis Externa; Pentacyclic Triterpenes; Plant Leaves; Polycyclic Compounds; Sulfonamides; Tetradecanoylphorbol Acetate; Triterpenes

2006
Nimesulide-induced antipyresis in rats involves both cyclooxygenase-dependent and independent mechanisms.
    European journal of pharmacology, 2006, Aug-14, Volume: 543, Issue:1-3

    Topics: Analgesics, Non-Narcotic; Animals; Arachidonic Acid; Body Temperature; Chemokine CCL3; Chemokine CCL4; Corticotropin-Releasing Hormone; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endothelin-1; Fever; Indomethacin; Injections, Intraperitoneal; Injections, Intraventricular; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophage Inflammatory Proteins; Male; Rats; Rats, Wistar; Sulfonamides; Time Factors; Tumor Necrosis Factor-alpha

2006
Acetaminophen, phenacetin and dipyrone do not modulate pressor responses to arachidonic Acid or to pressor agents.
    Pharmacology, 2007, Volume: 80, Issue:4

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blood Pressure; Cyclooxygenase 2 Inhibitors; Dipyrone; Phenacetin; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides

2007
Effects of cyclooxygenase inhibition on canine coronary artery blood flow and thrombosis.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:1

    Topics: Acetylcholine; Animals; Arachidonic Acid; Benzofurans; Carotid Arteries; Coronary Circulation; Coronary Vessels; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Epoprostenol; Inflammation; Ligation; Lipopolysaccharides; Naproxen; Platelet Aggregation; Propionates; Pyrazoles; Receptors, Epoprostenol; Sulfonamides; Thrombosis; Time Factors; Vasodilation; Vasodilator Agents

2008
Polymorphic human prostaglandin H synthase-2 proteins and their interactions with cyclooxygenase substrates and inhibitors.
    The pharmacogenomics journal, 2011, Volume: 11, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Eicosapentaenoic Acid; Gene Expression; Humans; Polymorphism, Genetic; Substrate Specificity; Sulfonamides

2011
Purification and characterization of the recombinant human prostaglandin H synthase-2 expressed in Pichia pastoris.
    Protein expression and purification, 2012, Volume: 83, Issue:2

    Topics: Arachidonic Acid; Cyclooxygenase 2; Detergents; Histidine; Humans; Indomethacin; Oligopeptides; Pichia; Recombinant Proteins; Sulfonamides

2012