nimesulide has been researched along with 4-nitro-2-(4'-hydroxyphenoxy)methanesulfonanilide in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bartosek, I; Castoldi, D; Gandini, R; Montalto, C; Monzani, V; Nava, ML; Scaricabarozzi, I; Vargiu, G | 1 |
| Castoldi, D; Monzani, V; Tofanetti, O | 1 |
| Casolaro, V; de Paulis, A; Guidi, G; Marino, O; Marone, G; Meliota, S; Patella, V | 1 |
| Aldini, G; Carini, M; Maffei Facino, R; Morelli, R; Saibene, L | 1 |
| Aldini, G; Calloni, MT; Carini, M; Maffei Facino, R | 1 |
| Gupta, SK; Mathur, P; Sengupta, S; Velpandian, T | 1 |
| Deby, CM; Deby-Dupont, GP; Henrotin, YE; Lamy, MM; Mouithys-Mickalad, AM; Reginster, JY; Zheng, SX | 1 |
| Bianchi, M; Ferrario, P | 1 |
| Curti, C; Dorta, DJ; Freitas, CS; Mingatto, FE; Pardo-Andreu, GL; Pestana, CR; Santos, AC; Tudella, VG; Uyemura, SA | 1 |
| Chen, X; Jiang, J; Pang, X; Zhong, D; Zhou, L | 1 |
| Chandra Halder, U; Dan, S; Das, D; Halder, D; Kumar Pal, T; Sarkar, P | 1 |
1 trial(s) available for nimesulide and 4-nitro-2-(4'-hydroxyphenoxy)methanesulfonanilide
| Article | Year |
|---|---|
LC-MS/MS determination of 4-hydroxynimesulide, an active metabolite of nimesulide and application to bioequivalence study in Indian subjects.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Female; Healthy Volunteers; Humans; India; Male; Sulfonamides; Tandem Mass Spectrometry; Therapeutic Equivalency; Young Adult | 2019 |
10 other study(ies) available for nimesulide and 4-nitro-2-(4'-hydroxyphenoxy)methanesulfonanilide
| Article | Year |
|---|---|
First dose and steady state pharmacokinetics of nimesulide and its 4-hydroxy metabolite in healthy volunteers.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Half-Life; Humans; Male; Reference Values; Sulfonamides | 1991 |
Simultaneous determination of nimesulide and hydroxynimesulide in human plasma and urine by high-performance liquid chromatography.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Humans; Middle Aged; Sulfonamides | 1988 |
Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells.
Topics: Adolescent; Adult; Alprostadil; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Bryostatins; Calcimycin; Colforsin; Complement C5a; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Lactones; Leukotriene C4; Lung; Macrolides; Mast Cells; Middle Aged; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandin D2; Skin; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Differential inhibition of superoxide, hydroxyl and peroxyl radicals by nimesulide and its main metabolite 4-hydroxynimesulide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Depression, Chemical; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Humans; Hydroxyl Radical; In Vitro Techniques; Iron; Kinetics; Lipid Peroxidation; Peroxides; Phosphatidylcholines; Reactive Oxygen Species; Sulfonamides; Superoxides; Synovial Fluid | 1995 |
Hydroxynimesulide, the main metabolite of nimesulide, prevents hydroperoxide/hemoglobin-induced hemolysis of rat erythrocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzene Derivatives; Chromatography, High Pressure Liquid; Drug Interactions; Erythrocyte Membrane; Erythrocytes; Hemoglobins; Hemolysis; Male; Membrane Proteins; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfonamides | 1997 |
Comparative analgesic activity of nimesulide and diclofenac by intramuscular route: correlation with pharmacokinetic profile of nimesulide.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cyclooxygenase Inhibitors; Diclofenac; Female; Injections, Intramuscular; Male; Mice; Pain; Sulfonamides | 1998 |
In vitro study of the antioxidant properties of non steroidal anti-inflammatory drugs by chemiluminescence and electron spin resonance (ESR).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Chlorine; Diclofenac; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; In Vitro Techniques; Indicators and Reagents; Indomethacin; Iron; Kinetics; Lipid Peroxidation; Luminescent Measurements; Neutrophil Activation; Neutrophils; Nitrates; Reactive Oxygen Species; Sodium Hypochlorite; Spectrophotometry, Ultraviolet; Sulfonamides; Tetradecanoylphorbol Acetate | 2000 |
Simultaneous determination of nimesulide and hydroxynimesulide in rat plasma, cerebrospinal fluid and brain by liquid chromatography using solid-phase extraction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Calibration; Chromatography, Liquid; Linear Models; Male; Rats; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Sulfonamides | 2003 |
4-hydroxy nimesulide effects on mitochondria and HepG2 cells. A comparison with nimesulide.
Topics: Animals; Cell Line, Tumor; Cell Survival; Glutathione; Glutathione Disulfide; Humans; Male; Membrane Potential, Mitochondrial; Mitochondria, Liver; NADP; Oxidation-Reduction; Permeability; Rats; Rats, Wistar; Sulfhydryl Compounds; Sulfonamides | 2007 |
Nimesulide and 4'-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile Acids and Salts; Carrier Proteins; Cell Culture Techniques; Chemical and Drug Induced Liver Injury; Cholestasis; Dose-Response Relationship, Drug; Hepatocytes; Liver Function Tests; Male; Membrane Glycoproteins; Metabolic Networks and Pathways; Rats, Wistar; Sulfonamides | 2017 |