nifurtimox has been researched along with quinone* in 1 studies
1 other study(ies) available for nifurtimox and quinone
| Article | Year |
|---|---|
Mode of action of p-quinone derivatives with trypanocidal activity studied by experimental and in silico models.
Quinones are attractive pharmacological scaffolds for developing new agents for the treatment of different transmissible and non-transmissible human diseases due to their capacity to alter the cell redox homeostasis. The bioactivity and potential mode of action of 19 p-quinone derivatives fused to different aromatic rings (carbo or heterocycles) and harboring distinct substituents were investigated in infective Trypanosoma brucei brucei. All the compounds, except for a furanequinone (EC Topics: Chagas Disease; Computer Simulation; Humans; Nifurtimox; Oxidation-Reduction; Quinones; Trypanocidal Agents; Trypanosoma cruzi | 2023 |