nifedipine has been researched along with warfarin in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (7.69) | 18.7374 |
| 1990's | 12 (30.77) | 18.2507 |
| 2000's | 11 (28.21) | 29.6817 |
| 2010's | 12 (30.77) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Li, QP; Rao, MR; Yang, JR | 1 |
| Kaufmann, E; Levy, PS; Rich, S | 1 |
| Blasco, R; Candenas, L; Castedo, L; Cortes, D; D'Ocon, P; Ivorra, D; López, S; Villaverde, C | 1 |
| Brücke, P; Herbinger, W; Leisch, F | 1 |
| Fels, PW; Fioretti, P; Hugenholtz, PG; Serruys, PW; Simoons, ML; van den Brand, M | 1 |
| Simonsen, S | 1 |
| Brée, F; Carrupt, PA; Giroud, Y; Testa, B; Tillement, JP; Tsai, RS; Urien, S | 1 |
| Buters, JT; Friedman, FK; Koley, AP; Markowitz, A; Robinson, RC | 1 |
| Bliesath, H; Hartmann, M; Huber, R; Radtke, HW; Steinijans, VW; Wurst, W; Zech, K | 1 |
| Ogata, M; Ohe, M; Shirato, K; Takishima, T | 1 |
| Dong, MS; Gillam, EM; Guengerich, FP; Johnson, WW; Shimada, T; Yamazaki, H | 1 |
| Inoue, K; Mimura, M; Nakamura, S; Oda, H; Ohmori, S; Shimada, T; Yamazaki, H | 1 |
| Högemann, A; Jonkman, JH; Lins, R; Sennewald, R; van Heiningen, PN; van Lier, JJ | 1 |
| Shimada, T; Yamazaki, H | 1 |
| Crespi, CL; Davitt, CM; Hu, M; Huang, SM; Li, Y; Penman, BW; Thummel, K | 1 |
| Cantrell, VE; Eckstein, J; Hall, SD; Hamman, MA; Jones, DR; Ring, BJ; Ruterbories, K; Williams, JA; Wrighton, SA | 1 |
| Booth-Genthe, C; Carr, B; Fang, Y; Lu, P; Norcross, R; Rodrigues, AD; Rushmore, T; Shou, M | 1 |
| King, BM; Pelletier, RD; Wong, YN; Zhang, ZY | 1 |
| He, L; Hou, X; Jiang, Q; Wang, S; Zhou, M | 1 |
| Bi, HC; Huang, L; Huang, M; Liu, YH; Wang, YT; Xue, XP | 1 |
| Eghbal, M; Imenshahidi, M; Iranshahi, M; Sahebkar, A | 1 |
| Chen, XY; Guo, LX; Li, W; Liu, YP; Mao, SY; Qu, XJ; Teng, Z; Wang, QR; Zhang, YF; Zhong, DF; Zhu, YT | 1 |
2 review(s) available for nifedipine and warfarin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Lack of pantoprazole drug interactions in man.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin | 1994 |
6 trial(s) available for nifedipine and warfarin
| Article | Year |
|---|---|
The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diltiazem; Humans; Hypertension, Pulmonary; Nifedipine; Prospective Studies; Pulmonary Artery; Survival Rate; Vascular Resistance; Warfarin | 1992 |
Clinical course after attempted thrombolysis in myocardial infarction. Results of pilot studies and preliminary data from a randomized trial.
Topics: Clinical Trials as Topic; Coronary Vessels; Coumarins; Exercise Test; Female; Fibrinolysis; Follow-Up Studies; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Nifedipine; Nitroglycerin; Pilot Projects; Random Allocation; Streptokinase; Urokinase-Type Plasminogen Activator | 1982 |
Pharmacological effects on coronary haemodynamics. A comparative study between atenolol, verapamil, nifedipine and carbocromen.
Topics: Atenolol; Chromonar; Coronary Circulation; Coronary Disease; Coumarins; Hemodynamics; Humans; Nifedipine; Oxygen Consumption; Propanolamines; Pyridines; Verapamil | 1981 |
Lack of pantoprazole drug interactions in man.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin | 1994 |
Pharmacokinetic drug interaction studies with candesartan cilexetil.
Topics: Adolescent; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Digoxin; Drug Interactions; Female; Glyburide; Humans; Hydrochlorothiazide; Male; Middle Aged; Nifedipine; Tetrazoles; Warfarin | 1997 |
Effects of Apatinib on the Pharmacokinetics of Nifedipine and Warfarin in Patients with Advanced Solid Tumors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Female; Humans; Male; Middle Aged; Neoplasms; Nifedipine; Pyridines; Warfarin; Young Adult | 2020 |
32 other study(ies) available for nifedipine and warfarin
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
[Protective effects of praeruptorin C and nifedipine on ischemia-reperfused injury in working rat hearts].
Topics: Animals; Calcium; Calcium Channel Blockers; Coumarins; Creatine Kinase; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Rats; Rats, Sprague-Dawley | 1992 |
Inhibition of calcium entry induced by cularines and isocrasifoline in uterine smooth muscle.
Topics: Alkaloids; Animals; Calcium; Coumarins; Female; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle, Smooth; Nifedipine; Oxytocin; Papaverine; Rats; Rats, Inbred Strains; Uterine Contraction; Vanadates | 1991 |
Role of percutaneous transluminal coronary angioplasty in patients with variant angina and coexistent coronary stenosis refractory to maximal medical therapy.
Topics: Adult; Angina Pectoris, Variant; Angiography; Angioplasty, Balloon; Aspirin; Constriction, Pathologic; Coronary Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nifedipine; Nitrates; Recurrence; Warfarin | 1984 |
Mechanism of ligand binding to alpha 1-acid glycoprotein (orosomucoid): correlated thermodynamic factors and molecular parameters of polarity.
Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Hydrogen Bonding; Indoles; Isradipine; Ligands; Nifedipine; Orosomucoid; Progesterone; Propanolamines; Propranolol; Temperature; Thermodynamics; Warfarin | 1995 |
CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.
Topics: Animals; Carbon Monoxide; Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Ethinyl Estradiol; Humans; Kinetics; Mixed Function Oxygenases; Nifedipine; Protein Binding; Quinidine; Recombinant Proteins; Spodoptera; Substrate Specificity; Testosterone; Time Factors; Transfection; Warfarin | 1995 |
Effects of a combination therapy of anticoagulant and vasodilator on the long-term prognosis of primary pulmonary hypertension.
Topics: Adolescent; Adult; Drug Combinations; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Isoproterenol; Male; Middle Aged; Nifedipine; Prognosis; Survival Rate; Warfarin | 1993 |
Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chlorzoxazone; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochromes b5; Escherichia coli; Ethanolamines; Humans; Hydroxylation; Mixed Function Oxygenases; Mutation; NADP; Nifedipine; Oxidation-Reduction; Phospholipids; Recombinant Proteins; Testosterone; Theophylline; Tolbutamide; Warfarin | 1997 |
Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans.
Topics: Adrenergic beta-Antagonists; Aniline Compounds; Animals; Antineoplastic Agents; Benzphetamine; Carcinogens; Coumarins; Cytochrome P-450 Enzyme System; Dogs; Erythromycin; Ethanolamines; Ethylmorphine; Guinea Pigs; Humans; Macaca fascicularis; Mephenytoin; Microsomes, Liver; Nifedipine; Oxazines; Oxidation-Reduction; Phenacetin; Phenytoin; Rats; Species Specificity | 1997 |
Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes.
Topics: Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Cholecalciferol; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Ethanolamines; Humans; Isoenzymes; Lauric Acids; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Omeprazole; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Paclitaxel; Prostaglandins; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Theophylline; Tretinoin; Warfarin; Xenobiotics | 1999 |
Transport and metabolic characterization of Caco-2 cells expressing CYP3A4 and CYP3A4 plus oxidoreductase.
Topics: Anticoagulants; Antineoplastic Agents, Hormonal; Biological Transport; Caco-2 Cells; Calcium Channel Blockers; Carcinogens; Cell Division; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diuretics, Osmotic; GABA Modulators; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Indoles; Mammary Tumor Virus, Mouse; Mannitol; Microscopy, Electron; Microsomes; Midazolam; Mixed Function Oxygenases; Nifedipine; Oxidoreductases; Propranolol; Pyridines; Sympatholytics; Testosterone; Tetradecanoylphorbol Acetate; Transfection; Tritium; Warfarin | 1999 |
Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7.
Topics: Alprazolam; Aryl Hydrocarbon Hydroxylases; Biotransformation; Clarithromycin; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochromes b5; Diltiazem; Estradiol; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Midazolam; Nifedipine; Tamoxifen; Testosterone; Triazolam | 2002 |
Characterization of the rhesus monkey CYP3A64 enzyme: species comparisons of CYP3A substrate specificity and kinetics using baculovirus-expressed recombinant enzymes.
Topics: Amino Acid Sequence; Animals; Baculoviridae; Base Sequence; Blotting, Western; Cell Line; Cloning, Molecular; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Ketoconazole; Kinetics; Liver; Macaca mulatta; Microsomes, Liver; Midazolam; Molecular Sequence Data; Nifedipine; Recombinant Proteins; Sequence Analysis, DNA; Spodoptera; Substrate Specificity; Testosterone | 2006 |
Delineation of the interactions between the chemotherapeutic agent eribulin mesylate (E7389) and human CYP3A4.
Topics: Adult; Aged; Antineoplastic Agents; Cells, Cultured; Child; Child, Preschool; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Furans; Hepatocytes; Humans; Infant, Newborn; Ketones; Male; Microsomes, Liver; Middle Aged; Nifedipine; Recombinant Proteins; Testosterone; Warfarin | 2008 |
A vascular smooth muscle/cell membrane chromatography-offline-gas chromatography/mass spectrometry method for recognition, separation and identification of active components from traditional Chinese medicines.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Cell Membrane; Cells, Cultured; Chromatography; Coumarins; Drugs, Chinese Herbal; Furocoumarins; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2009 |
CAR-mediated up-regulation of CYP3A4 expression in LS174T cells by Chinese herbal compounds.
Topics: Calcium Channel Blockers; Cell Line, Tumor; Constitutive Androstane Receptor; Coumarins; Cytochrome P-450 CYP3A; Drugs, Chinese Herbal; Enzyme Induction; Gene Expression; Genes, Reporter; Humans; Luciferases; Nifedipine; Plasmids; Receptors, Cytoplasmic and Nuclear; RNA; RNA, Messenger; Transcriptional Activation; Transfection; Up-Regulation | 2011 |
Hypotensive activity of auraptene, a monoterpene coumarin from Citrus spp.
Topics: Animals; Antihypertensive Agents; Arterial Pressure; Citrus; Coumarins; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; Nifedipine; Rats; Rats, Wistar | 2013 |