nifedipine and urapidil

nifedipine has been researched along with urapidil in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's8 (40.00)18.2507
2000's5 (25.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Lombardo, F; Obach, RS; Waters, NJ1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Grosser, KD; Späh, F; Thieme, G1
Adams, HA; Allerkamp, S; Börgmann, A; Hempelmann, G1
Anger, C; Hemelrijck, J; Lauwers, T; Mattheussen, M; Van Aken, H; Wüsten, R1
Puchstein, C1
Feldhaus, P; Haerlin, R; Stumpe, KO1
Heinz, G; Hirschl, MM; Laggner, AN; Seidler, D; Sterz, F; Wagner, A; Zeiner, A1
Zanchetti, A1
Bur, A; Herkner, H; Hirschl, MM; Kürkciyan, I; Laggner, AN; Müllner, M; Seidler, D1
Kal, JE; Spaan, JA; Van Wezel, HB; Vergroesen, I1
Grieshaber, M; Schwietzer, G; Stahl, RA; Wenzel, UO1
Eckert, RE; Karsten, AJ; Utz, J; Ziegler, M1
Stiefelhagen, P1
Allolio, B; Ertl, G; Fassnacht, M; Frantz, S; Hu, K; Kleinbrahm, K; Maier, SK; Weismann, D1
Lou, N; Wang, DF; Wang, Z1

Trials

5 trial(s) available for nifedipine and urapidil

ArticleYear
[Sympatho-adrenergic reactions during drug-induced hypotension. A comparative study on probands].
    Der Anaesthesist, 1990, Volume: 39, Issue:3

    Topics: Adult; Blood Pressure; Epinephrine; Female; Ferricyanides; Heart Rate; Humans; Hypotension, Controlled; Male; Nifedipine; Nitroglycerin; Nitroprusside; Norepinephrine; Piperazines; Vasodilator Agents

1990
[Antihypertensive effect and tolerance to urapidil. Comparison with nifedipine in a multicenter double-blind study].
    Fortschritte der Medizin, 1989, Jan-15, Volume: 107, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Nifedipine; Piperazines; Random Allocation

1989
Intravenous urapidil versus sublingual nifedipine in the treatment of hypertensive urgencies.
    The American journal of emergency medicine, 1993, Volume: 11, Issue:6

    Topics: Acute Disease; Administration, Sublingual; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Drug Resistance; Emergencies; Humans; Hypertension; Injections, Intravenous; Middle Aged; Myocardial Contraction; Nifedipine; Piperazines; Prospective Studies; Time Factors

1993
Addition of urapidil or metoprolol to the treatment of hypertensive non-responders to nifedipine monotherapy: efficacy and metabolic effects. Italian Urapidil Study Group.
    Blood pressure. Supplement, 1995, Volume: 3

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Piperazines

1995
Myocardial oxygen supply:demand ratio as reference for coronary vasodilatory drug effects in humans.
    Heart (British Cardiac Society), 1997, Volume: 78, Issue:2

    Topics: Aged; Cardiac Catheterization; Cardiac Pacing, Artificial; Coronary Artery Bypass; Coronary Circulation; Coronary Disease; Felodipine; Female; Humans; Male; Middle Aged; Myocardium; Nifedipine; Nitroprusside; Oxygen Consumption; Piperazines; Prospective Studies; Reference Values; Vasodilator Agents

1997

Other Studies

15 other study(ies) available for nifedipine and urapidil

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Acute haemodynamic effects of urapidil and nifedipine in hypertensive urgencies and emergencies.
    Drugs, 1990, Volume: 40 Suppl 4

    Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Emergencies; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Piperazines

1990
[Effect of nifedipine and urapidil on autoregulation of cerebral circulation in the presence of an intracranial space occupying lesion].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1990, Volume: 25, Issue:2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Cerebrovascular Circulation; Dogs; Female; Hemodynamics; Homeostasis; Infusions, Intravenous; Intracranial Pressure; Male; Nifedipine; Piperazines

1990
Treatment of hypertensive crises in neurosurgery.
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:5

    Topics: Animals; Antihypertensive Agents; Cerebrovascular Circulation; Dogs; Hemodynamics; Humans; Hypertension; Intracranial Pressure; Neurosurgery; Nifedipine; Nitroprusside; Piperazines

1989
Efficacy of different antihypertensive drugs in the emergency department.
    Journal of human hypertension, 1996, Volume: 10 Suppl 3

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Emergency Medical Services; Enalaprilat; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Piperazines; Treatment Outcome

1996
[Diagnostic and therapeutic procedures by doctors for patients in a hypertensive crisis. An inquiry in 56 internal medicine clinics].
    Deutsche medizinische Wochenschrift (1946), 1998, Apr-09, Volume: 123, Issue:15

    Topics: Acute Disease; Administration, Sublingual; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Contraindications; Emergencies; Humans; Hypertension; Injections, Intravenous; Myocardial Infarction; Nifedipine; Nitroglycerin; Piperazines; Pulmonary Edema; Surveys and Questionnaires; Time Factors; Vasodilator Agents

1998
Regulation of renal artery smooth muscle tone by alpha1-adrenoceptors: role of voltage-gated calcium channels and intracellular calcium stores.
    Urological research, 2000, Volume: 28, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Diltiazem; Dioxanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Ischemia; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phenoxybenzamine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Renal Artery; Renal Circulation; Swine; Thapsigargin; Verapamil

2000
[When hypertension becomes an emergency case: lower the blood pressure, but slowly!].
    MMW Fortschritte der Medizin, 2003, May-29, Volume: 145, Issue:22

    Topics: Administration, Oral; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Diagnosis, Differential; Dihydralazine; Emergencies; Hospitalization; Humans; Hypertension; Hypertension, Malignant; Injections, Intravenous; Nifedipine; Nitrendipine; Nitroglycerin; Piperazines; Time Factors; Vasodilator Agents

2003
Prevention of hypertensive crises in rats induced by acute and chronic norepinephrine excess.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2010, Volume: 42, Issue:11

    Topics: Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; Infusion Pumps; Male; Nifedipine; Norepinephrine; Phenoxybenzamine; Piperazines; Rats

2010
[Efficacy of sublingual nifedipine and intravenous urapidil for treatment of acute postoperative hypertension].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2011, Volume: 31, Issue:2

    Topics: Administration, Sublingual; Aged; Antihypertensive Agents; Female; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Neoplasms; Nifedipine; Piperazines; Postoperative Complications; Retrospective Studies

2011