nifedipine and telmisartan

nifedipine has been researched along with telmisartan in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (24.24)29.6817
2010's22 (66.67)24.3611
2020's3 (9.09)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Chang, G; Mathialagan, S; Ryu, S; Varma, MVS; Woody, N1
Bertone, G; Ciccarelli, L; Cicero, AF; Derosa, G; Fogari, E; Fogari, R; Piccinni, MN1
Corradi, L; Fogari, R; Mugellini, A; Pasotti, C; Preti, P; Rinaldi, A; Zoppi, A1
Akai, T; Hanyu, H; Iwamoto, T; Sakurai, H; Sato, T; Takasaki, A1
Albert, DH; Banfor, PN; Cox, BF; Davidsen, SK; Franklin, PH; Fryer, RM; Gintant, GA; Larson, KJ; Noonan, WT; Segreti, JA; Tapang, P; Widomski, DL1
Harada, N; Okajima, K; Shimozawa, N1
Brody, R; Grossman, E; Peleg, E; Sharabi, Y1
Bilo, G; Choi, J; Kilama, MO; Mancia, G; Parati, G; Ruilope, LM1
Derosa, G; Maffioli, P1
Boiocchi, C; Bozzini, S; Buzzi, MP; Choi, J; D'Angelo, A; Esposito, C; Falcone, C; Mancia, G; Ochan Kilama, M; Schirinzi, S; Torreggiani, M1
Chen, S; Chen, W; Du, H; Fan, J; Lan, X; Ling, Z; Liu, Z; Su, L; Woo, K; Xiao, P; Xu, Y; Yin, Y; Zhou, B1
Damen, CW; González, O; Hankemeier, T; van der Kloet, FM; van Vliet, M; Vreeken, RJ1
D'Angelo, A; Dario Ragonesi, P; Derosa, G; Franzetti, I; Maffioli, P; Querci, F1
Chen, Y; Fan, Z; Liu, H1
Agostoni, P; Anza-Ramìrez, C; Bilo, G; Caravita, S; Faini, A; Lang, M; Macarlupu, JL; Parati, G; Salvioni, E; Villafuerte, FC1
Bilo, G; Caravita, S; Faini, A; Lang, M; Parati, G1
Chen, H; Fan, L; Li, X; Tian, G; Wu, Y1
Abd El Aziz, AE; El Sayed, NS; Sallam, NA; Sayed, RH1

Reviews

4 review(s) available for nifedipine and telmisartan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022
Nifedipine and telmisartan for the treatment of hypertension: the TALENT study.
    Expert review of cardiovascular therapy, 2011, Volume: 9, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Calcium Channel Blockers; Cardiovascular Diseases; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Hypertension; Nifedipine; Randomized Controlled Trials as Topic; Risk Factors; Telmisartan

2011
Calcium channel blockers for pulmonary arterial hypertension.
    The Cochrane database of systematic reviews, 2015, Sep-25, Issue:9

    Topics: Aged; Benzimidazoles; Benzoates; Calcium Channel Blockers; Humans; Hypertension, Pulmonary; Middle Aged; Nifedipine; Randomized Controlled Trials as Topic; Telmisartan

2015

Trials

7 trial(s) available for nifedipine and telmisartan

ArticleYear
Comparison of the effects of telmisartan and nifedipine gastrointestinal therapeutic system on blood pressure control, glucose metabolism, and the lipid profile in patients with type 2 diabetes mellitus and mild hypertension: a 12-month, randomized, doubl
    Clinical therapeutics, 2004, Volume: 26, Issue:8

    Topics: Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Nifedipine; Telmisartan; Treatment Outcome; Triglycerides

2004
Effect of telmisartan/hydrochlorothiazide combination versus nifedipine GITS on ambulatory blood pressure and sympathetic activation.
    American journal of hypertension, 2005, Volume: 18, Issue:5 Pt 1

    Topics: Adult; Aged; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Prospective Studies; Sympathetic Nervous System; Telmisartan

2005
Blood pressure control by the nifedipine GITS-telmisartan combination in patients at high cardiovascular risk: the TALENT study.
    Journal of hypertension, 2011, Volume: 29, Issue:3

    Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Risk; Telmisartan

2011
Microalbuminuria and sRAGE in high-risk hypertensive patients treated with nifedipine/telmisartan combination treatment: a substudy of TALENT.
    Mediators of inflammation, 2012, Volume: 2012

    Topics: Adolescent; Adult; Aged; Albuminuria; Antihypertensive Agents; Benzimidazoles; Benzoates; Drug Combinations; Female; Glycation End Products, Advanced; Humans; Hypertension; Male; Middle Aged; Nifedipine; Telmisartan; Young Adult

2012
Effect of nifedipine versus telmisartan on prevention of atrial fibrillation recurrence in hypertensive patients.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Atrial Fibrillation; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Echocardiography; Electrocardiography; Female; Follow-Up Studies; Heart Atria; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Secondary Prevention; Telmisartan; Treatment Outcome

2013
Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:10

    Topics: Adipokines; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Combinations; Female; Glucose Clamp Technique; Humans; Hydrochlorothiazide; Hypertension; Insulin Resistance; Losartan; Male; Middle Aged; Nifedipine; Telmisartan

2015
Blood pressure response to six-minute walk test in hypertensive subjects exposed to high altitude: effects of antihypertensive combination treatment.
    International journal of cardiology, 2016, Sep-15, Volume: 219

    Topics: Adult; Altitude; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Telmisartan; Treatment Outcome; Walk Test

2016

Other Studies

22 other study(ies) available for nifedipine and telmisartan

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
    Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Identification of Organic Anion Transporter 2 Inhibitors: Screening, Structure-Based Analysis, and Clinical Drug Interaction Risk Assessment.
    Journal of medicinal chemistry, 2022, 11-10, Volume: 65, Issue:21

    Topics: Drug Interactions; HEK293 Cells; Humans; Liver; Organic Anion Transporters, Sodium-Independent; Risk Assessment

2022
[A patient with early Alzheimer's disease who showed improvement of cognitive function and cerebral perfusion by combined therapy of nilvadipine and PPAR gamma agonists].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2008, Volume: 45, Issue:4

    Topics: Aged; Alzheimer Disease; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Calcium Channel Blockers; Cerebrovascular Circulation; Cognition; Humans; Male; Nifedipine; PPAR gamma; Telmisartan

2008
Effect of the multitargeted receptor tyrosine kinase inhibitor, ABT-869 [N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea], on blood pressure in conscious rats and mice: reversal with antihypertensive agents and effect on tumor growt
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Acrylates; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enalapril; Humans; Imidazoles; Indazoles; Lisinopril; Male; Mice; Mice, SCID; Neoplasms; Nifedipine; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Ramipril; Rats; Rats, Sprague-Dawley; Telmisartan; Thiophenes; Xenograft Model Antitumor Assays

2009
AT(1) receptor blockers increase insulin-like growth factor-I production by stimulating sensory neurons in spontaneously hypertensive rats.
    Translational research : the journal of laboratory and clinical medicine, 2009, Volume: 154, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Ganglia, Spinal; Hypertension; Imidazoles; Insulin-Like Growth Factor I; Kidney; Losartan; Male; Myocardium; Nifedipine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; RNA, Messenger; Sensory Receptor Cells; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilator Agents

2009
Production and secretion of adiponectin from 3T3-L1 adipocytes: comparison of antihypertensive drugs.
    American journal of hypertension, 2009, Volume: 22, Issue:10

    Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Captopril; Hydrochlorothiazide; Losartan; Mice; Nifedipine; RNA, Messenger; Telmisartan

2009
Matrix Effect Compensation in Small-Molecule Profiling for an LC-TOF Platform Using Multicomponent Postcolumn Infusion.
    Analytical chemistry, 2015, Jun-16, Volume: 87, Issue:12

    Topics: Acetaminophen; Benzimidazoles; Benzoates; Biphenyl Compounds; Chromatography, High Pressure Liquid; Clomipramine; Dihydropyridines; Enkephalin, Leucine; Humans; Mass Spectrometry; Nifedipine; Pharmaceutical Preparations; Simvastatin; Telmisartan; Tetrazoles; Time Factors

2015
Role of acetazolamide and telmisartan/nifedipine-GITS combination in antagonizing the blood pressure rise induced by high altitude exposure.
    International journal of cardiology, 2016, Dec-15, Volume: 225

    Topics: Acetazolamide; Altitude; Altitude Sickness; Benzimidazoles; Benzoates; Blood Pressure; Gastrointestinal Tract; Humans; Hypertension; Nifedipine; Telmisartan

2016
Pregnancy-induced complications in IgA nephropathy: A case report.
    Medicine, 2018, Volume: 97, Issue:15

    Topics: Adult; Antihypertensive Agents; Benzimidazoles; Benzoates; Biopsy; Blood Pressure; Cyclophosphamide; Drug Therapy, Combination; Female; Follow-Up Studies; Glomerulonephritis, IGA; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Kidney; Nifedipine; Prednisone; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Stillbirth; Telmisartan

2018
Neuroprotective Effects of Telmisartan and Nifedipine Against Cuprizone-Induced Demyelination and Behavioral Dysfunction in Mice: Roles of NF-κB and Nrf2.
    Inflammation, 2021, Volume: 44, Issue:4

    Topics: Animals; Cuprizone; Demyelinating Diseases; Hand Strength; Locomotion; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; NF-E2-Related Factor 2; NF-kappa B; Nifedipine; Telmisartan

2021