nifedipine and tacrolimus

nifedipine has been researched along with tacrolimus in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (13.79)18.2507
2000's16 (55.17)29.6817
2010's8 (27.59)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dong, G; Liu, N; Sheng, C; Tu, J; Wang, Y1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Fujihira, S; Ishida, H; Mine, Y; Mitamura, T; Noguchi, H; Ohara, K; Yamada, A1
Gordon, FD; Jenkins, RL; Lewis, WD; Marcos-Alvarez, A; Seifeldin, RA1
Hatase, O; Lu, YF; Matsui, H; Moriwaki, A; Onuma, H; Tokuda, M; Tomizawa, K1
Greenstein, SM; Kim, DY; Schechner, RS; Schreiber, TC; Sun, S; Tellis, VA1
Hashii, M; Higashida, H; Minabe, Y1
Beighton, D; O'Brien, G; Roberts, GJ; Sheehy, EC1
Elia, MG; Greco, S; Jiménez, E; Marsigliante, S; Muscella, A; Storelli, C1
Kelly, D; McKaig, SJ; Shaw, L1
Fukushi, H; Morishima, Y; Shirasaki, Y; Takano, H1
Araki, T; Asakura, H; Koshino, T; Nakai, A; Oya, A; Taniuchi, Y1
Furness, PN; Murphy, GJ; Nicholson, ML; Sandford, RS; Waller, JR1
Fitzsimonds, RM; Krueger, SR; Picciotto, MR; Stevens, TR1
Aoyama, M; Chen, SR; Furuzono, S; Goto, T; Hotta, S; Imaizumi, Y; Ito, Y; Matsubara, T; Nakayama, S; Ohya, S; Shimokata, K; Wang, J; Yamada, A1
Bénitah, JP; Perrier, E; Perrier, R; Richard, S1
Imaizumi, Y; Liu, HN; Nakayama, S; Ohya, S; Wang, J1
Balasubramaniam, R; Chawla, S; Grace, AA; Huang, CL1
Iwasaki, K1
Barr, LA; Berretta, RM; Gao, H; Houser, SR; Kubo, H; Makarewich, CA; Molkentin, JD; Wang, F; Wang, W; Zhang, H1
Arik, N; Cetinkaya, BO; Erisgin, Z; Gacar, A; Gulbahar, MY; Keles, GC; Pamuk, F1

Reviews

4 review(s) available for nifedipine and tacrolimus

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Emerging New Targets for the Treatment of Resistant Fungal Infections.
    Journal of medicinal chemistry, 2018, 07-12, Volume: 61, Issue:13

    Topics: Antifungal Agents; Drug Resistance, Fungal; Humans; Molecular Targeted Therapy; Mycoses

2018
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022
Metabolism of tacrolimus (FK506) and recent topics in clinical pharmacokinetics.
    Drug metabolism and pharmacokinetics, 2007, Volume: 22, Issue:5

    Topics: Biotransformation; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Monitoring; Enzyme Inhibitors; Humans; Immunoenzyme Techniques; Immunosuppressive Agents; Ketoconazole; Molecular Structure; Nifedipine; Polymorphism, Single Nucleotide; Tacrolimus

2007

Trials

3 trial(s) available for nifedipine and tacrolimus

ArticleYear
Nifedipine interaction with tacrolimus in liver transplant recipients.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:5

    Topics: Adult; Aged; Calcium Channel Blockers; Creatinine; Drug Interactions; Female; Humans; Hypertension; Immunosuppressive Agents; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Nifedipine; Retrospective Studies; Tacrolimus

1997
Investigation of the effect of FK506 (tacrolimus) and cyclosporin on gingival overgrowth following paediatric liver transplantation.
    International journal of paediatric dentistry, 2002, Volume: 12, Issue:6

    Topics: Adolescent; Analysis of Variance; Calcium Channel Blockers; Child; Child, Preschool; Cyclosporine; Double-Blind Method; Gingiva; Gingival Overgrowth; Humans; Immunosuppressive Agents; Infant; Liver Transplantation; Nifedipine; Prospective Studies; Statistics, Nonparametric; Tacrolimus

2002
Randomized clinical trial of the effect of microemulsion cyclosporin and tacrolimus on renal allograft fibrosis.
    The British journal of surgery, 2003, Volume: 90, Issue:6

    Topics: Adult; Analysis of Variance; Aspirin; Cyclosporine; Extracellular Matrix; Female; Fibrosis; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Prednisolone; Prospective Studies; Tacrolimus; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination

2003

Other Studies

22 other study(ies) available for nifedipine and tacrolimus

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Tacrolimus (FK506)-induced nephrotoxicity in spontaneous hypertensive rats.
    The Journal of toxicological sciences, 1994, Volume: 19, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arterioles; Blood Urea Nitrogen; Creatinine; Hypertension; Kidney; Kidney Diseases; Male; Nifedipine; Rats; Rats, Inbred SHR; Renal Artery; Renin; Tacrolimus; Thromboxane B2; Vasoconstriction

1994
A calcineurin inhibitor, FK506, blocks voltage-gated calcium channel-dependent LTP in the hippocampus.
    Neuroscience research, 1998, Volume: 30, Issue:4

    Topics: Animals; Calcineurin Inhibitors; Calcium Channel Blockers; Calcium Channels; Cyclosporine; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Immunosuppressive Agents; Ion Channel Gating; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Nifedipine; Tacrolimus; Tetraethylammonium

1998
Nifedipine prevents tacrolimus-induced intestinal hemodynamic and functional impairments.
    Transplantation proceedings, 1998, Volume: 30, Issue:6

    Topics: Animals; Hemodynamics; Intestinal Absorption; Intestine, Small; Maltose; Nifedipine; Rats; Rats, Inbred Lew; Regional Blood Flow; Tacrolimus; Time Factors; Transplantation, Isogeneic; Vascular Resistance

1998
cADP-ribose potentiates cytosolic Ca2+ elevation and Ca2+ entry via L-type voltage-activated Ca2+ channels in NG108-15 neuronal cells.
    The Biochemical journal, 2000, Jan-15, Volume: 345 Pt 2

    Topics: Adenosine Diphosphate Ribose; Biological Transport; Calcium; Calcium Channels, L-Type; Cells, Cultured; Cyclic ADP-Ribose; Cytosol; Ion Channel Gating; Manganese; Membrane Potentials; Models, Biological; NAD; Neurons; Niacinamide; Nifedipine; Patch-Clamp Techniques; Ryanodine; Ryanodine Receptor Calcium Release Channel; Tacrolimus

2000
Oral health in children undergoing liver transplantation.
    International journal of paediatric dentistry, 2000, Volume: 10, Issue:2

    Topics: Adolescent; Case-Control Studies; Chi-Square Distribution; Child; Child, Preschool; Cyclosporine; Dental Caries; Dental Plaque; Dental Plaque Index; DMF Index; Female; Follow-Up Studies; Gingival Overgrowth; Gingivitis; Humans; Immunosuppressive Agents; Liver Failure; Liver Transplantation; Male; Nifedipine; Periodontal Index; Prevalence; Reproducibility of Results; Socioeconomic Factors; Statistics as Topic; Statistics, Nonparametric; Tacrolimus; Tooth, Deciduous

2000
Muscarinic acetylcholine receptor activation induces Ca2+ mobilization and Na+/K+-ATPase activity inhibition in eel enterocytes.
    The Journal of endocrinology, 2002, Volume: 173, Issue:2

    Topics: Analysis of Variance; Animals; Calcineurin Inhibitors; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Eels; Enterocytes; Enzyme Activation; Enzyme Inhibitors; Naphthalenes; Nifedipine; Protein Kinase C; Receptors, Cholinergic; Sirolimus; Sodium; Sodium-Potassium-Exchanging ATPase; Tacrolimus; Thapsigargin; Type C Phospholipases

2002
Calmodulin and calmodulin-dependent kinase II mediate neuronal cell death induced by depolarization.
    Brain research, 2003, Feb-07, Volume: 962, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Death; Cells, Cultured; Cerebral Cortex; Egtazic Acid; Enzyme Inhibitors; Fetus; Kinetics; Membrane Potentials; Neurons; NG-Nitroarginine Methyl Ester; Nifedipine; Nitriles; Pyrethrins; Rats; Sulfonamides; Tacrolimus; Trifluoperazine; Veratridine

2003
Windows of therapeutic opportunity on fetal growth retardation induced by transient intrauterine ischemia in rats.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2002, Volume: 69, Issue:6

    Topics: Animals; Cyclic N-Oxides; Dizocilpine Maleate; Female; Fetal Growth Retardation; Fetal Hypoxia; Ischemia; Neuroprotective Agents; Nifedipine; Nitrogen Oxides; Pregnancy; Random Allocation; Rats; Rats, Wistar; Tacrolimus

2002
Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Nov-05, Volume: 23, Issue:31

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Calcineurin; Calcineurin Inhibitors; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Neurotoxins; Nicotine; Nifedipine; Receptors, Nicotinic; Tacrolimus

2003
Requirement of ryanodine receptors for pacemaker Ca2+ activity in ICC and HEK293 cells.
    Journal of cell science, 2004, Jun-01, Volume: 117, Issue:Pt 13

    Topics: Anesthetics, Local; Animals; Biological Clocks; Boron Compounds; Caffeine; Calcium; Calcium Channel Blockers; Cell Line; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Fura-2; Humans; Ileum; Immunohistochemistry; Kinetics; Macrocyclic Compounds; Mice; Microscopy, Fluorescence; Muscle, Smooth; Nifedipine; Oxazoles; Proto-Oncogene Proteins c-kit; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; Tacrolimus; Tetracaine

2004
Ca2+ controls functional expression of the cardiac K+ transient outward current via the calcineurin pathway.
    The Journal of biological chemistry, 2004, Sep-24, Volume: 279, Issue:39

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcineurin; Calcium; Calcium Channel Agonists; Calmodulin; Cells, Cultured; Chelating Agents; Culture Media, Serum-Free; Cyclosporine; Down-Regulation; Egtazic Acid; Electrophysiology; Kinetics; Models, Biological; Nifedipine; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Shal Potassium Channels; Signal Transduction; Tacrolimus; Temperature; Time Factors

2004
Involvement of ryanodine receptors in pacemaker Ca2+ oscillation in murine gastric ICC.
    Biochemical and biophysical research communications, 2005, Mar-11, Volume: 328, Issue:2

    Topics: Animals; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cells, Cultured; Gastric Mucosa; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Mice; Mice, Inbred BALB C; Myocytes, Smooth Muscle; Nifedipine; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel; Stomach; Tacrolimus; Tissue Distribution

2005
Caffeine-induced arrhythmias in murine hearts parallel changes in cellular Ca(2+) homeostasis.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:4

    Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cytosol; Diltiazem; Electric Stimulation; Homeostasis; Immunosuppressive Agents; In Vitro Techniques; Mice; Mice, Inbred Strains; Myocytes, Cardiac; Nifedipine; Perfusion; Phosphodiesterase Inhibitors; Ryanodine Receptor Calcium Release Channel; Tachycardia, Ventricular; Tacrolimus

2005
Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling.
    Journal of molecular and cellular cardiology, 2012, Volume: 53, Issue:5

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Calcium Signaling; Cardiomegaly; Cell Nucleus; Cells, Cultured; Heart Ventricles; Imidazoles; Myocytes, Cardiac; NFATC Transcription Factors; Nickel; Nifedipine; Protein Transport; Rats; Rats, Sprague-Dawley; Tacrolimus; TRPC Cation Channels; Ventricular Remodeling

2012
Effects of tacrolimus and nifedipine, alone or in combination, on gingival tissues.
    Journal of periodontology, 2013, Volume: 84, Issue:11

    Topics: Animals; Blood Vessels; Calcium Channel Blockers; Cell Count; Collagen; Connective Tissue; Drug Combinations; Epithelium; Fibroblasts; Gene Expression Regulation, Enzymologic; Gingiva; Gingival Overgrowth; Immunosuppressive Agents; Male; Nifedipine; PTEN Phosphohydrolase; Random Allocation; Rats; Rats, Sprague-Dawley; Tacrolimus; Time Factors

2013