nifedipine and suramin

nifedipine has been researched along with suramin in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (40.74)18.2507
2000's10 (37.04)29.6817
2010's5 (18.52)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Mallard, NJ; Marshall, RW; Sithers, AJ; Spriggs, TL1
Mallard, N; Marshall, R; Sithers, A; Spriggs, B1
Giachetti, A; Maggi, CA; Santicioli, P; Zagorodnyuk, V1
Galligan, JJ; Harpstead, T; Herring, A1
Bültmann, R; Cunnane, TC; Driessen, B; Elrick, DB; Starke, K; von Kügelgen, I1
Bültmann, R; Starke, K1
Kurz, K; Starke, K; von Kügelgen, I1
Furukawa, T; Katsuragi, T; Usune, S1
Hirst, GD; Reilly, MJ1
Carabelli, V; Carbone, E; Carra, I1
Drmota, T; Krůsek, J; Novotný, J; Svoboda, P1
Kwan, CY; Shen, JZ; Zheng, XF1
Boselli, C; Grana, E1
Chen, L; Cho, H; Harada, N; Nagata, N; Tomoda, K; Yamashita, T1
Leite, M; Rohatgi, R; Satlin, LM; Woda, CB1
Cleary, L; Docherty, JR; Vandeputte, C1
Fanò, G; Guarnieri, S; Mariggiò, MA; Rathbone, MP1
Avellar, MC; Caricati-Neto, A; Jurkiewicz, A; Jurkiewicz, NH; Reuter, HR; Verde, LF1
Chow, JY; Dong, H; Dong, X; Insel, PA; Kim, HD; Ko, KH; Lee, J; Smoll, EJ1
Gao, J; Gui, Y; Li, JJ; Sun, X; Walsh, MP; Wang, Z; Zheng, XL1
Hu, J; Huang, C; Lin, AH; Paudel, O; Ran, P; Sham, JS; Subedi, KP1
Dai, G; Jia, Z; Li, J; Li, X; Liu, J; Niu, B; Sun, W; Wang, H; Wang, Y; Wu, X; Ye, R; Zhao, Z1
Fountain, SJ; Gonzalez-Montelongo, MDC1

Other Studies

27 other study(ies) available for nifedipine and suramin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Separation of putative alpha 1A- and alpha 1B-adrenoceptor mediated components in the tension response of the rat vas deferens to electrical field stimulation.
    British journal of pharmacology, 1992, Volume: 105, Issue:3

    Topics: Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Suramin; Vas Deferens

1992
Suramin: a selective inhibitor of purinergic neurotransmission in the rat isolated vas deferens.
    European journal of pharmacology, 1992, Sep-10, Volume: 220, Issue:1

    Topics: Adenosine Triphosphate; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Nifedipine; Norepinephrine; Purinergic Antagonists; Rats; Rats, Wistar; Suramin; Synaptic Transmission; Vas Deferens

1992
Evidence that tachykinin NK1 and NK2 receptors mediate non-adrenergic non-cholinergic excitation and contraction in the circular muscle of guinea-pig duodenum.
    British journal of pharmacology, 1995, Volume: 115, Issue:2

    Topics: Action Potentials; Adenosine Diphosphate; Animals; Apamin; Arginine; Atropine; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Guanethidine; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; Nifedipine; Nitroarginine; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Suramin; Thionucleotides

1995
Pharmacological characterization of purinoceptor-mediated constriction of submucosal arterioles in guinea pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:3

    Topics: Adenosine Triphosphate; Animals; Arterioles; Calcium; Calcium Channel Blockers; Guinea Pigs; Ileum; Intestinal Mucosa; Nifedipine; Purinergic Agonists; Purinergic Antagonists; Pyridoxal Phosphate; Receptors, Purinergic; Suramin; Vasoconstrictor Agents

1995
The fade of the purinergic neurogenic contraction of the guinea-pig vas deferens: analysis of possible mechanisms.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:5

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Calcium Channels; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Nifedipine; Norepinephrine; Prazosin; Receptors, Purinergic; Suramin; Triazines; Vas Deferens

1994
Evans blue blocks P2X-purinoceptors in rat vas deferens.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:6

    Topics: Adenosine Triphosphate; Animals; Evans Blue; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Potassium; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Suramin; Vas Deferens

1993
Axon terminal P2-purinoceptors in feedback control of sympathetic transmitter release.
    Neuroscience, 1993, Volume: 56, Issue:2

    Topics: Adenosine Triphosphate; Animals; Axons; Desipramine; Drug Interactions; Feedback; GTP-Binding Proteins; Male; Mice; Nifedipine; Norepinephrine; Prazosin; Purinergic Antagonists; Receptors, Purinergic; Suramin; Sympathetic Nervous System; Triazines; Vas Deferens; Virulence Factors, Bordetella; Xanthines; Yohimbine

1993
Effects of PPADS and suramin on contractions and cytoplasmic Ca2+ changes evoked by AP4A, ATP and alpha, beta-methylene ATP in guinea-pig urinary bladder.
    British journal of pharmacology, 1996, Volume: 117, Issue:4

    Topics: Adenosine Triphosphate; Calcium; Calcium Channel Blockers; Cytoplasm; Dinucleoside Phosphates; In Vitro Techniques; Muscle Contraction; Nifedipine; Pyridoxal Phosphate; Suramin; Urinary Bladder

1996
Differences in the responses to purinergic nerve stimulation and applied ATP in the guinea-pig vas deferens.
    Journal of the autonomic nervous system, 1996, Feb-05, Volume: 57, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Male; Membrane Potentials; Nifedipine; Suramin; Vas Deferens

1996
Localized secretion of ATP and opioids revealed through single Ca2+ channel modulation in bovine chromaffin cells.
    Neuron, 1998, Volume: 20, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Analgesics; Analgesics, Opioid; Animals; Antineoplastic Agents; Autocrine Communication; Barium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Cattle; Chromaffin Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Exocytosis; Ion Channel Gating; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Opioid Peptides; Patch-Clamp Techniques; Peptides; Receptors, Opioid; Receptors, Purinergic; Spider Venoms; Suramin; Virulence Factors, Bordetella

1998
Overexpression of the G protein G11alpha prevents desensitization of Ca2+ response to thyrotropin-releasing hormone.
    Life sciences, 1999, Volume: 65, Issue:9

    Topics: Animals; Bradykinin; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line; Dose-Response Relationship, Drug; Egtazic Acid; Gene Expression; GTP-Binding Proteins; Humans; Inositol Phosphates; Nifedipine; Rats; Receptors, Thyrotropin-Releasing Hormone; Suramin; Thapsigargin; Thyrotropin-Releasing Hormone; Time Factors; Transfection

1999
Evidence for P(2)-purinoceptors contribution in H(2)O(2)-induced contraction of rat aorta in the absence of endothelium.
    Cardiovascular research, 2000, Aug-18, Volume: 47, Issue:3

    Topics: Adenosine Triphosphate; Alkaloids; Analysis of Variance; Animals; Aorta; Apyrase; Benzylisoquinolines; Calcium; Calcium Channel Blockers; Catalase; Dantrolene; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Evans Blue; Hydrogen Peroxide; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nickel; Nifedipine; Procaine; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Signal Transduction; Superoxide Dismutase; Suramin; Triazines; Vasoconstrictor Agents

2000
Differential effects of drugs interacting with autonomic transmitters on responses of rat vas deferens to field stimulation.
    Journal of autonomic pharmacology, 2000, Volume: 20, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Drug Interactions; Electric Stimulation; Male; Muscle Contraction; Neurotransmitter Agents; Nifedipine; Prazosin; Rats; Rats, Wistar; Suramin; Vas Deferens; Vasodilator Agents; Verapamil

2000
Extracellular adenosine 5'-ATP-induced calcium signaling in isolated vestibular ganglion cells of the guinea pig.
    Acta oto-laryngologica, 2000, Volume: 120, Issue:6

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases; Cochlea; Enzyme Inhibitors; Extracellular Space; Fluorescence; Guinea Pigs; Humans; Immunohistochemistry; Neurons, Afferent; Nifedipine; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Spiral Ganglion; Suramin; Time Factors; Triazines; Vestibule, Labyrinth

2000
Effects of luminal flow and nucleotides on [Ca(2+)](i) in rabbit cortical collecting duct.
    American journal of physiology. Renal physiology, 2002, Volume: 283, Issue:3

    Topics: Adenosine Triphosphate; Animals; Boron Compounds; Calcium; Calcium Channels, L-Type; Female; Gap Junctions; Kidney Cortex; Kidney Tubules, Collecting; Nifedipine; Nucleotides; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Suramin; Thapsigargin; Uridine Triphosphate

2002
Investigation of postjunctional alpha1- and alpha2-adrenoceptor subtypes in vas deferens from wild-type and alpha(2A/D)-adrenoceptor knockout mice.
    British journal of pharmacology, 2003, Volume: 138, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Cocaine; Electric Stimulation; Imidazoles; Indoles; Isoindoles; Isometric Contraction; Male; Mice; Mice, Knockout; Nifedipine; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Purinergic; Suramin; Thymine; Vas Deferens; Yohimbine

2003
Cooperation in signal transduction of extracellular guanosine 5' triphosphate and nerve growth factor in neuronal differentiation of PC12 cells.
    Neuroscience, 2004, Volume: 128, Issue:4

    Topics: Animals; Barbiturates; Blotting, Western; Calcium; Calcium Channel Blockers; Cell Count; Cell Differentiation; Chelating Agents; Clotrimazole; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Extracellular Space; Fluorescent Antibody Technique; Fluorescent Dyes; Gallic Acid; Growth Inhibitors; Guanosine Triphosphate; Ionomycin; Ionophores; Isoxazoles; Membrane Potentials; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nerve Growth Factor; Neurites; Nifedipine; PC12 Cells; Pertussis Toxin; Pyridoxal Phosphate; Rats; Signal Transduction; Suramin; Time Factors; Triazines

2004
Sympathetic neurotransmission in the rat testicular capsule: functional characterization and identification of mRNA encoding alpha1-adrenoceptor subtypes.
    European journal of pharmacology, 2006, Aug-14, Volume: 543, Issue:1-3

    Topics: Acetyl-CoA C-Acyltransferase; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Male; Muscle Contraction; Nifedipine; Norepinephrine; Prazosin; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P2; Reserpine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spiperone; Suramin; Sympathetic Nervous System; Synaptic Transmission; Testis

2006
P2Y receptors mediate Ca2+ signaling in duodenocytes and contribute to duodenal mucosal bicarbonate secretion.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:2

    Topics: Adenosine Diphosphate; Aminoquinolines; Animals; Bicarbonates; Boron Compounds; Calcium Channel Blockers; Calcium Signaling; Cell Line; Dogs; Duodenum; Epithelial Cells; Estrenes; Female; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestinal Secretions; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Nifedipine; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Time Factors; Uridine Triphosphate

2009
Uridine adenosine tetraphosphate induces contraction of airway smooth muscle.
    American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 301, Issue:5

    Topics: Animals; Bronchi; Calcium; Calcium Channels, L-Type; Dinucleoside Phosphates; Male; Muscle Contraction; Muscle, Smooth; Myography; Nifedipine; Protein Kinase Inhibitors; Purinergic P2X Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Signal Transduction; Suramin; Trachea

2011
Extracellular Adenosine Diphosphate Ribose Mobilizes Intracellular Ca2+ via Purinergic-Dependent Ca2+ Pathways in Rat Pulmonary Artery Smooth Muscle Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 37, Issue:5

    Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cells, Cultured; Estrenes; Imidazoles; Ions; Male; Myocytes, Smooth Muscle; Nifedipine; Pulmonary Artery; Purinergic P2X Receptor Antagonists; Purinergic P2Y Receptor Antagonists; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Signal Transduction; Suramin; TRPM Cation Channels; Type C Phospholipases

2015
Adenosine Triphosphate (ATP) Inhibits Voltage-Sensitive Potassium Currents in Isolated Hensen's Cells and Nifedipine Protects Against Noise-Induced Hearing Loss in Guinea Pigs.
    Medical science monitor : international medical journal of experimental and clinical research, 2016, Jun-13, Volume: 22

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Guinea Pigs; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Nifedipine; Organ of Corti; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Random Allocation; Signal Transduction; Suramin

2016
Neuropeptide Y facilitates P2X1 receptor-dependent vasoconstriction via Y1 receptor activation in small mesenteric arteries during sympathetic neurogenic responses.
    Vascular pharmacology, 2021, Volume: 136

    Topics: Adenosine Triphosphate; Adrenergic alpha-1 Receptor Antagonists; Animals; Benzenesulfonates; Calcium Channel Blockers; Calcium Channels, L-Type; Male; Mesenteric Arteries; Mice, Inbred C57BL; Neuropeptide Y; Nifedipine; Prazosin; Receptors, Neuropeptide Y; Receptors, Purinergic P2X1; Suramin; Sympathetic Nervous System; Vasoconstriction

2021