nifedipine and rifampin

nifedipine has been researched along with rifampin in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.50)	18.7374
1990's	5 (12.50)	18.2507
2000's	16 (40.00)	29.6817
2010's	17 (42.50)	24.3611
2020's	1 (2.50)	2.80

Authors

Authors	Studies
Burk, O; Eichelbaum, M; Geick, A	1
Beaumont, K; Smith, DA; van De Waterbeemd, H; Walker, DK	1
Jekerle, V; Piquette-Miller, M; Teng, S	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Alborzi, A; Edraki, N; Javidnia, K; Khoshneviszadeh, M; Mardaneh, J; Miri, R; Pourabbas, B	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y	1
Bharate, SS; Vishwakarma, RA	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF	1
Kimura, H; Kusaba, T; Nagasawa, K; Otsuka, T; Sakata, T; Tada, Y; Tsuda, Y	1
Fukami, K; Haze, K; Hiramori, K; Kishimoto, H; Saito, M; Sumiyoshi, T; Tsuchihashi, K	1
Hoener, BA	1
Fromm, MF; Heidemann, H; Holtbecker, N; Kroemer, HK; Ohnhaus, EE	1
Bardou, LG; Berthou, F; Dréano, Y; Iribarne, C; Ménez, JF	1
Abdu-Aguye, I; Mustapha, A; Ndanusa, BU	1
Anzenbacher, P; Anzenbacherová, E; Bachleda, P; Modrianský, M; Simánek, V; Ulrichová, J; Walterová, D	1
Assenat, E; Drocourt, L; Fabre, JM; Maurel, P; Pascussi, JM; Vilarem, MJ	1
Echizen, H; Fukuda, J; Furuie, K; Hayashi, T; Saima, S; Yoshimoto, H	1
Ali, RY; Matheny, CJ; Pollack, GM; Yang, X	1
Marks, B; Raucy, J; Trubetskoy, O; Yueh, MF; Zielinski, T	1
de Morais, SM; Fahmi, OA; Liras, JL; Maurer, TS; Mills, JB; Ripp, SL; Trevena, KA	1
Azuma, J; Hou, XL; Kinoshita, N; Komatsu, K; Qiu, F; Takahashi, K; Tanaka, K	1
Hayashi, M; Shou, M; Skiles, GL; Xu, Y; Zhou, Y	1
Baneyx, G; Iliadis, A; Lavé, T; Meille, C; Parrott, N	1
Chiang, TS; Chiou, LL; Huang, GT; Lee, HS; Yang, KC	1

Reviews

3 review(s) available for nifedipine and rifampin

Article	Year
Property-based design: optimization of drug absorption and pharmacokinetics. Journal of medicinal chemistry, 2001, Apr-26, Volume: 44, Issue:9 Topics: Animals; Biological Transport; Blood Proteins; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane; Drug Design; Eye; Humans; Intestinal Absorption; Models, Biological; Models, Molecular; Nasal Mucosa; Pharmaceutical Preparations; Pharmacokinetics; Prodrugs; Skin Absorption	2001
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators. European journal of medicinal chemistry, 2022, Jul-05, Volume: 237 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells	2022

Trials

1 trial(s) available for nifedipine and rifampin

Article	Year
The effect of single does of rifampicin on the pharmacokinetics of oral nifedipine. Journal of pharmaceutical and biomedical analysis, 1997, Volume: 15, Issue:9-10 Topics: Administration, Oral; Adult; Antibiotics, Antitubercular; Drug Interactions; Half-Life; Humans; Male; Nifedipine; Reference Values; Rifampin	1997

Other Studies

36 other study(ies) available for nifedipine and rifampin

Article	Year
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. The Journal of biological chemistry, 2001, May-04, Volume: 276, Issue:18 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Dimerization; DNA; DNA Primers; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestines; Molecular Sequence Data; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Rifampin; Transcription Factors	2001
Induction of ABCC3 (MRP3) by pregnane X receptor activators. Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:11 Topics: Animals; Cell Line, Tumor; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Multidrug Resistance-Associated Proteins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger	2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Synthesis and biological evaluation of some new 1,4-dihydropyridines containing different ester substitute and diethyl carbamoyl group as anti-tubercular agents. Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4 Topics: Antitubercular Agents; Dihydropyridines; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Mycobacterium tuberculosis; Structure-Activity Relationship	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans. European journal of medicinal chemistry, 2010, Volume: 45, Issue:11 Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index	2014
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7 Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics	2015
Case report: nifedipine-rifampicin interaction attenuates the effect on blood pressure in a patient with essential hypertension. The American journal of the medical sciences, 1992, Volume: 303, Issue:1 Topics: Adrenergic alpha-Antagonists; Aged; Blood Pressure; Drug Interactions; Ethambutol; Female; Humans; Hypertension; Isoniazid; Nicardipine; Nifedipine; Propranolol; Quinazolines; Rifampin	1992
A case of variant angina exacerbated by administration of rifampicin. Heart and vessels, 1987, Volume: 3, Issue:4 Topics: Aged; Angina Pectoris, Variant; Biological Availability; Drug Interactions; Humans; Male; Microsomes, Liver; Nifedipine; Rifampin; Tuberculosis, Pulmonary	1987
Predicting the hepatic clearance of xenobiotics in humans from in vitro data. Biopharmaceutics & drug disposition, 1994, Volume: 15, Issue:4 Topics: Biological Availability; Chlorzoxazone; Cytochrome P-450 Enzyme System; Humans; Hydrocortisone; Lidocaine; Liver; Mathematics; Metabolic Clearance Rate; Mexiletine; Nifedipine; Predictive Value of Tests; Rifampin; Xenobiotics	1994
The nifedipine-rifampin interaction. Evidence for induction of gut wall metabolism. Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:10 Topics: Adult; Antibiotics, Antitubercular; Area Under Curve; Calcium Channel Blockers; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Intestinal Mucosa; Male; Mixed Function Oxygenases; Nifedipine; Reference Values; Rifampin	1996
Interaction of methadone with substrates of human hepatic cytochrome P450 3A4. Toxicology, 1997, Feb-14, Volume: 117, Issue:1 Topics: Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Diazepam; Fluvoxamine; Humans; Methadone; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Rifampin	1997
Human hepatocyte--a model for toxicological studies. Functional and biochemical characterization. General physiology and biophysics, 2000, Volume: 19, Issue:2 Topics: 7-Alkoxycoumarin O-Dealkylase; Adult; Antioxidants; Calcium Channel Blockers; Cell Culture Techniques; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Hepatocytes; Humans; L-Lactate Dehydrogenase; Liver; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Nifedipine; Rifampin; Silymarin; tert-Butylhydroperoxide; Time Factors; Toxicity Tests	2000
Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:10 Topics: Aryl Hydrocarbon Hydroxylases; Calcium Channels; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dihydropyridines; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Hepatocytes; Humans; Kinetics; Mixed Function Oxygenases; Nifedipine; Oxidoreductases, N-Demethylating; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rifampin; RNA, Messenger; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Time Factors	2001
The effects of rifampicin on the pharmacokinetics and pharmacodynamics of orally administered nilvadipine to healthy subjects. British journal of clinical pharmacology, 2002, Volume: 53, Issue:2 Topics: Administration, Oral; Adult; Antibiotics, Antitubercular; Blood Pressure; Calcium Channel Blockers; Drug Interactions; Female; Heart Rate; Humans; Hydrocortisone; Male; Nifedipine; Rifampin	2002
Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:9 Topics: Actins; Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Brain; Cytochrome P-450 CYP3A; Dexamethasone; Drug Administration Schedule; Enzyme Induction; Gene Expression Regulation; Hypericum; Intestine, Small; Intubation; Liver; Male; Mice; Mice, Inbred Strains; Nifedipine; Oxidoreductases, N-Demethylating; Plant Extracts; Pregnane X Receptor; Pregnenolone Carbonitrile; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rifampin; Tamoxifen; Time Factors	2004
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line. The AAPS journal, 2005, Mar-04, Volume: 7, Issue:1 Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Clotrimazole; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Enzyme Induction; Genes, Reporter; Genes, Synthetic; Humans; Ketoconazole; Liver Neoplasms; Lovastatin; Luciferases; Mifepristone; Neoplasm Proteins; Nifedipine; Omeprazole; Paclitaxel; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Thiazolidinediones; Transcription, Genetic; Troglitazone; Troleandomycin	2005
Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:10 Topics: Algorithms; Carbamazepine; Cell Line; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Nifedipine; Phenobarbital; Phenytoin; Pioglitazone; Reproducibility of Results; Rifampin; Rosiglitazone; Sulfinpyrazone; Thiazolidinediones	2006
Possible inhibitory mechanism of Curcuma drugs on CYP3A4 in 1alpha,25 dihydroxyvitamin D3 treated Caco-2 cells. International journal of pharmaceutics, 2007, Jun-07, Volume: 337, Issue:1-2 Topics: Caco-2 Cells; Calcitriol; Cell Survival; Curcuma; Curcumin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Herb-Drug Interactions; Humans; Hydroxylation; Inhibitory Concentration 50; Intestinal Mucosa; Ketoconazole; Nifedipine; Oxidation-Reduction; Plant Extracts; Rhizome; Rifampin; RNA, Messenger; Testosterone	2007
Simulation of clinical drug-drug interactions from hepatocyte CYP3A4 induction data and its potential utility in trial designs. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Area Under Curve; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Midazolam; Nifedipine; Phenobarbital; Rifampin; Simvastatin; Substrate Specificity	2011
Physiologically based pharmacokinetic modeling of CYP3A4 induction by rifampicin in human: influence of time between substrate and inducer administration. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Jun-02, Volume: 56 Topics: Alfentanil; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Hepatocytes; Humans; Midazolam; Models, Biological; Nifedipine; Rifampin; Tissue Distribution; Triazolam	2014
Enhancement of CYP3A4 activity in Hep G2 cells by lentiviral transfection of hepatocyte nuclear factor-1 alpha. PloS one, 2014, Volume: 9, Issue:4 Topics: Apoptosis; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; HEK293 Cells; Hep G2 Cells; Hepatocyte Nuclear Factor 1-alpha; Humans; Lentivirus; Nifedipine; Rifampin; Transduction, Genetic; Transfection	2014