nifedipine and quinine

nifedipine has been researched along with quinine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.63)18.7374
1990's9 (28.13)18.2507
2000's7 (21.88)29.6817
2010's10 (31.25)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN1
Bateman, A; Belcourt, D; Bennett, HP; Hamilton, JR; Hu, J; MacLeod, RJ; Solomon, S1
Røed, A1
Bazill, GW; Dexter, TM1
Cossu, MF; Edwards, C; Enomoto, K; Maeno, T; Oka, T1
Lawal, OB; Savage, AO1
Oiki, S; Okada, Y; Ueda, S1
Okada, Y; Tsuchiya, W; Yada, T1
Abrunhosa, AJ; Antunes, CM; Barbosa, RM; Rosário, LM; Santos, RM; Silva, AM1
Archer, K; Buchheit, KH; Cook, SJ; Elliott, KR; Foster, RW; Fozard, JR; Martin, A; Miller, AJ; Müller, T; Small, RC1
Ortiz-Miranda, SI; Pappone, PA1
Hume, RI; Lin, X; Nuttall, AL1
Kucera, P; Prod'hom, B; Sabovcik, R1
Ishizaki, T; Zhao, XJ1
Choi, YH; Lee, MG1
Kawai, T; Kuninishi, Y; Muraki, Y; Nogawa, H1

Reviews

1 review(s) available for nifedipine and quinine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

31 other study(ies) available for nifedipine and quinine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
    Chemical biology & drug design, 2016, Volume: 88, Issue:6

    Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain

2016
Corticostatic peptides cause nifedipine-sensitive volume reduction in jejunal villus enterocytes.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Jan-15, Volume: 88, Issue:2

    Topics: Amino Acid Sequence; Animals; Calcimycin; Epithelium; Gramicidin; Guinea Pigs; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Jejunum; Kinetics; Molecular Sequence Data; Muscle, Smooth; Nifedipine; Peptides; Quinine; Sequence Homology, Nucleic Acid; Sodium; Structure-Activity Relationship

1991
Selective potentiation of subtetanic and tetanic contractions by the calcium-channel antagonist nifedipine in the rat diaphragm preparation.
    General pharmacology, 1991, Volume: 22, Issue:2

    Topics: Animals; Caffeine; Calcium; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Male; Membranes; Muscle Contraction; Nifedipine; Phenytoin; Potassium; Quinine; Rats; Rats, Inbred Strains; Respiratory Muscles

1991
Role of endocytosis in the action of ether lipids on WEHI-3B, HL60, and FDCP-mix A4 cells.
    Cancer research, 1990, Dec-01, Volume: 50, Issue:23

    Topics: Animals; Antineoplastic Agents; Azepines; Cell Survival; Chloroquine; Diltiazem; Drug Synergism; Endocytosis; Furans; Humans; Hydroxyzine; In Vitro Techniques; Leukemia, Myeloid; Mice; Nifedipine; Phospholipid Ethers; Platelet Activating Factor; Pyridines; Quinidine; Quinine; Sodium Fluoride; Thiazoles; Triazoles; Verapamil

1990
Involvement of the Ca2+-dependent K+ channel activity in the hyperpolarizing response induced by epidermal growth factor in mammary epithelial cells.
    FEBS letters, 1986, Jul-28, Volume: 203, Issue:2

    Topics: Animals; Calcium; Epidermal Growth Factor; Epithelium; Female; Ion Channels; Mammary Glands, Animal; Membrane Potentials; Mice; Nifedipine; Potassium; Quinine; Ruthenium Red; Tetraethylammonium Compounds

1986
Influence of calcium lack and nifedipine on carbachol-, potassium- and quinine-induced contractions of the lizard isolated rectum.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1986, Volume: 85, Issue:2

    Topics: Animals; Calcium; Carbachol; Kinetics; Lizards; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Chloride; Quinine; Rectum

1986
Increases in cytosolic free Ca2+ induced by ATP, complement and beta-lipoprotein in mouse L fibroblasts.
    Biochemical and biophysical research communications, 1985, Oct-15, Volume: 132, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line; Complement System Proteins; Cytosol; Egtazic Acid; Fibroblasts; Lipoproteins, LDL; Membrane Potentials; Mice; Microelectrodes; Nifedipine; Potassium; Quinine

1985
Calcium channel and calcium pump involved in oscillatory hyperpolarizing responses of L-strain mouse fibroblasts.
    The Journal of physiology, 1982, Volume: 327

    Topics: Animals; Biological Transport, Active; Calcium; Dose-Response Relationship, Drug; Flavonoids; Ion Channels; L Cells; Membrane Potentials; Mice; Nifedipine; Potassium; Quinidine; Quinine

1982
Bursting electrical activity in pancreatic beta-cells: evidence that the channel underlying the burst is sensitive to Ca2+ influx through L-type Ca2+ channels.
    Pflugers Archiv : European journal of physiology, 1993, Volume: 424, Issue:5-6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Charybdotoxin; Female; In Vitro Techniques; Ionomycin; Islets of Langerhans; Membrane Potentials; Mice; Nifedipine; Potassium Channel Blockers; Quinine; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds

1993
Further analysis of the mechanisms underlying the tracheal relaxant action of SCA40.
    British journal of pharmacology, 1995, Volume: 114, Issue:1

    Topics: Animals; Cyclic AMP; Electric Stimulation; Electrophysiology; Female; Guinea Pigs; Imidazoles; Isoproterenol; Male; Nifedipine; Parasympatholytics; Pyrazines; Quinine; Theophylline; Trachea

1995
Blockers of voltage-gated K channels inhibit proliferation of cultured brown fat cells.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: Adipose Tissue, Brown; Animals; Animals, Newborn; Calcium; Cell Division; Cells, Cultured; Kinetics; Membrane Potentials; Nifedipine; Norepinephrine; Potassium Channels; Quinine; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil

1993
Dihydropyridines and verapamil inhibit voltage-dependent K+ current in isolated outer hair cells of the guinea pig.
    Hearing research, 1995, Volume: 88, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Cochlea; Guinea Pigs; Hair Cells, Auditory, Outer; Membrane Potentials; Nifedipine; Nimodipine; Patch-Clamp Techniques; Potassium Channel Blockers; Quinine; Verapamil

1995
Characterization of a whole-cell Ca2+-blockable monovalent cation current in isolated ectodermal cells of chick embryo.
    Pflugers Archiv : European journal of physiology, 1996, Volume: 431, Issue:4

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability; Chick Embryo; Ectoderm; Glutamates; Hydroxides; Nifedipine; Protons; Quinine; Verapamil

1996
Metabolic interactions of selected antimalarial and non-antimalarial drugs with the major pathway (3-hydroxylation) of quinine in human liver microsomes.
    British journal of clinical pharmacology, 1997, Volume: 44, Issue:5

    Topics: Anti-Infective Agents; Antimalarials; Chromatography; Cytochrome P-450 Enzyme System; Doxycycline; Drug Interactions; Erythromycin; Humans; Hydroxylation; Ketoconazole; Microsomes, Liver; Nifedipine; Omeprazole; Primaquine; Quinine; Tetracycline; Troleandomycin

1997
Pharmacokinetic and pharmacodynamic interaction between nifedipine and metformin in rats: competitive inhibition for metabolism of nifedipine and metformin by each other via CYP isozymes.
    Xenobiotica; the fate of foreign compounds in biological systems, 2012, Volume: 42, Issue:5

    Topics: Administration, Oral; Animals; Baculoviridae; Blood Proteins; Cell Line; Cytochrome P-450 CYP3A; Dexamethasone; Drug Interactions; Humans; Injections, Intravenous; Intestinal Mucosa; Intestines; Isoenzymes; Kinetics; Male; Metformin; Microsomes, Liver; Nifedipine; Protein Binding; Quinine; Rats; Rats, Sprague-Dawley; Sulfaphenazole; Troleandomycin

2012
Pharmacological characterisation of electrocardiogram J-T
    European journal of pharmacology, 2022, Jul-15, Volume: 927

    Topics: Animals; DNA-Binding Proteins; Electrocardiography; Flecainide; Guinea Pigs; Long QT Syndrome; Nifedipine; Quinidine; Quinine; Ranolazine; Sotalol; Torsades de Pointes; Verapamil

2022