nifedipine and quinapril

nifedipine has been researched along with quinapril in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (28.57)	18.2507
2000's	3 (21.43)	29.6817
2010's	7 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Sun, H	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Schömig, A; Schön, HR	1
Barthelmebs, M; Grima, M; Imbs, JL; Jund, A; Petitjean, P; Stephan, D; Vloemans, M	1
Schön, HR	1
Di Veroli, C; Gazzaniga, PP; Lenti, L; Marigliano, V; Pignatelli, P; Pulcinelli, FM; Riondino, S	1
Bareford, D; Beevers, DG; Islim, IF	1

Reviews

2 review(s) available for nifedipine and quinapril

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Medical treatment of chronic valvular regurgitation. The Journal of heart valve disease, 1995, Volume: 4 Suppl 2 Topics: Angiotensin-Converting Enzyme Inhibitors; Aortic Valve Insufficiency; Chronic Disease; Humans; Isoquinolines; Mitral Valve Insufficiency; Nifedipine; Quinapril; Tetrahydroisoquinolines; Vasodilator Agents; Ventricular Dysfunction, Left	1995

Trials

1 trial(s) available for nifedipine and quinapril

Article	Year
A single (investigator)-blind randomised control trial comparing the effects of quinapril and nifedipine on platelet function in patients with mild to moderate hypertension. Platelets, 2001, Volume: 12, Issue:5 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; beta-Thromboglobulin; Blood Platelets; Blood Pressure; Calcium Channel Blockers; Endothelium, Vascular; Female; Humans; Hypertension; Isoquinolines; Male; Matched-Pair Analysis; Middle Aged; Nifedipine; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Quinapril; Single-Blind Method; Tetrahydroisoquinolines	2001

Article

Year

A single (investigator)-blind randomised control trial comparing the effects of quinapril and nifedipine on platelet function in patients with mild to moderate hypertension.

Platelets, 2001, Volume: 12, Issue:5

Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; beta-Thromboglobulin; Blood Platelets; Blood Pressure; Calcium Channel Blockers; Endothelium, Vascular; Female; Humans; Hypertension; Isoquinolines; Male; Matched-Pair Analysis; Middle Aged; Nifedipine; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Quinapril; Single-Blind Method; Tetrahydroisoquinolines

2001

Other Studies

11 other study(ies) available for nifedipine and quinapril

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism. Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2 Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
[Long-term treatment with quinapril in chronic aortic and mitral insufficiency]. Deutsche medizinische Wochenschrift (1946), 1995, Mar-31, Volume: 120, Issue:13 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aortic Valve Insufficiency; Chronic Disease; Echocardiography; Female; Follow-Up Studies; Hemodynamics; Humans; Hydralazine; Isoquinolines; Male; Middle Aged; Mitral Valve Insufficiency; Nifedipine; Nitroprusside; Prodrugs; Quinapril; Radionuclide Ventriculography; Tetrahydroisoquinolines; Time Factors	1995
Short-term effects of quinapril and nifedipine on early renal changes in streptozotocin-induced diabetes in rats. Fundamental & clinical pharmacology, 1994, Volume: 8, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Body Weight; Carbon Dioxide; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Eating; Isoquinolines; Kidney; Male; Nifedipine; Oxygen; Partial Pressure; Peptidyl-Dipeptidase A; Quinapril; Rats; Rats, Wistar; Renal Circulation; Tetrahydroisoquinolines	1994
Platelet hyperactivity in hypertensive older patients is controlled by lowering blood pressure. Journal of the American Geriatrics Society, 1999, Volume: 47, Issue:8 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Blood Pressure; Calcium Channel Blockers; Endothelin-1; Female; Humans; Hypertension; Interleukin-1; Interleukin-6; Isoquinolines; Male; Nifedipine; P-Selectin; Platelet Activation; Platelet Aggregation; Prevalence; Prodrugs; Quinapril; Tetrahydroisoquinolines	1999