nifedipine has been researched along with pinacidil in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (32.50) | 18.7374 |
| 1990's | 11 (27.50) | 18.2507 |
| 2000's | 8 (20.00) | 29.6817 |
| 2010's | 8 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arch, JR; Buckle, DR; Fenwick, AE; Houge-Frydrych, CS; Pinto, IL; Smith, DG; Taylor, SG; Tedder, JM | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Adnitt, P; Battersby, C; Bulpitt, CJ; Fletcher, AE; Jurgensen, HJ; Underwood, N | 1 |
| Karim, OM; Mostwin, JL; Seki, N | 1 |
| Duty, S; Weston, AH | 1 |
| Fukushima, H; Izawa, T; Kashiwabara, T; Nakajima, S; Nishikori, K | 1 |
| Asano, M; Masuzawa, K; Matsuda, T | 1 |
| Satoh, E; Taira, N; Yanagisawa, T | 1 |
| Wilson, C | 1 |
| Hashimoto, H; Taira, N; Yanagisawa, T | 2 |
| Imamura, N; Kurokawa, K; Nakajima, S; Ueda, M | 1 |
| Cooper, SM; Wilson, C | 1 |
| Clapham, JC; Longman, SD | 1 |
| Imai, S; Matsui, K; Ogawa, Y | 1 |
| Jürgensen, HJ | 1 |
| Akbarali, HI; Bieger, D; Ohia, SE; Triggle, CR | 1 |
| Carlsen, JE; Steensgaard-Hansen, F | 1 |
| Nakajima, S; Ueda, M | 1 |
| Matsuda, S; Ueda, M | 1 |
| Mikkelsen, E; Pedersen, OL | 1 |
| Mikkelsen, EO; Poulsen, SH; Sehested, J | 1 |
| Pang, CC; Wang, YX; Zhou, T | 1 |
| Barth, HL; Hempelmann, RG; Mehdorn, HM; Pradel, RH; Ziegler, A | 1 |
| Baláti, B; Papp, JG; Varró, A | 1 |
| Chan, HY; Chen, ZY; Huang, Y; Ming, WC; Tsang, SY; Yao, X | 1 |
| Garfield, RE; Hankins, GD; Jain, V; Longo, M; Saade, GR; Vedernikov, YP | 1 |
| Kito, Y; Sanders, KM; Ward, SM | 1 |
| Bieger, D; Ford, C; Mong, K; Tabrizchi, R | 1 |
| Callaghan, BP; Cobine, CA; Keef, KD | 1 |
| Baker, PN; Fyfe, GK; Greenwood, SL; Sibley, CP; Williams, JL | 1 |
| Balducci, J; Baumbach, J; Coonrod, DV; Garfield, RE; Shi, L; Shi, SQ | 1 |
| Iwata, K; Kojima, A; Matsumoto, A; Nakaya, H; Nishida, H; Reien, Y; Shirayama, T; Yabe-Nishimura, C | 1 |
3 trial(s) available for nifedipine and pinacidil
| Article | Year |
|---|---|
Quality of life on antihypertensive therapy: a double-blind trial comparing quality of life on pinacidil and nifedipine in combination with a thiazide diuretic. European Pinacidil Study Group.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Data Interpretation, Statistical; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Guanidines; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pinacidil; Quality of Life; Sodium Chloride Symporter Inhibitors | 1992 |
Comparative effects of pinacidil and nifedipine in the treatment of arterial hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Guanidines; Humans; Hypertension; Multicenter Studies as Topic; Nifedipine; Pinacidil; Random Allocation | 1988 |
Effects of long term treatment with pinacidil and nifedipine on left ventricular anatomy and function in patients with mild to moderate systemic hypertension.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Echocardiography; Female; Guanidines; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Nifedipine; Organ Size; Pinacidil | 1988 |
37 other study(ies) available for nifedipine and pinacidil
| Article | Year |
|---|---|
Relaxant activity of 4-amido-3,4-dihydro-2H-1-benzopyran-3-ols and 4-amido-2H-1-benzopyrans on guinea pig isolated trachealis.
Topics: Amides; Animals; Benzopyrans; Bronchodilator Agents; Chemical Phenomena; Chemistry; Cromakalim; Guinea Pigs; Molecular Structure; Muscle Relaxation; Potassium Channels; Pyrroles; Structure-Activity Relationship; Trachea | 1990 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effect of pinacidil on the membrane electrical activity of guinea pig detrusor muscle.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Glyburide; Guanidines; Guinea Pigs; Membrane Potentials; Muscle, Smooth; Nifedipine; Pinacidil; Urinary Bladder; Vasodilator Agents | 1992 |
Characteristics of the contractile response of rabbit aorta produced by cromakalim in calcium-free solution.
Topics: Animals; Aorta; Benzopyrans; Calcium; Colforsin; Cromakalim; Guanidines; Male; Microelectrodes; Minoxidil; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Pinacidil; Potassium; Potassium Channels; Pyridines; Pyrroles; Rabbits; Vasoconstriction | 1992 |
Characteristics of KRN2391, a novel vasodilator, compared with those of cromakalim, pinacidil and nifedipine in rat aorta.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Guanidines; Guanylate Cyclase; Male; Muscle Relaxation; Nifedipine; Nitrogen Dioxide; Pinacidil; Potassium Channels; Pyridines; Pyrroles; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Vasodilator Agents | 1991 |
Evidence that pinacidil may promote the opening of ATP-sensitive K+ channels yet inhibit the opening of Ca2(+)-activated K+ channels in K(+)-contracted canine mesenteric artery.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium; Cromakalim; Dogs; Female; Glyburide; Guanidines; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Pinacidil; Potassium; Potassium Channels; Pyrroles; Rubidium Radioisotopes | 1990 |
Specific antagonism by glibenclamide of negative inotropic effects of potassium channel openers in canine atrial muscle.
Topics: Animals; Benzopyrans; Carbachol; Cromakalim; Dogs; Female; Glyburide; Guanidines; Heart Atria; Male; Myocardial Contraction; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1990 |
Inhibition by sulphonylureas of vasorelaxation induced by K+ channel activators in vitro.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Cromakalim; Drug Interactions; Glipizide; Glyburide; Guanidines; In Vitro Techniques; Male; Nifedipine; Norepinephrine; Pinacidil; Potassium Channels; Potassium Chloride; Pyrroles; Rabbits; Sulfonylurea Compounds; Tolbutamide; Vasodilator Agents | 1989 |
Interaction of potassium channel openers and blockers in canine atrial muscle.
Topics: Animals; Barium; Barium Compounds; Chlorides; Dogs; Female; Guanidines; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Quaternary Ammonium Compounds; Tetraethylammonium Compounds | 1989 |
A study on the hypotensive mechanism of pinacidil: relationship between its vasodilating effect and intracellular Ca2+ levels.
Topics: Animals; Antihypertensive Agents; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; Hydralazine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Pinacidil; Rabbits; Sulfonamides; Trifluoperazine; Vasodilation | 1989 |
Effect of cromakalim on contractions in rabbit isolated renal artery in the presence and absence of extracellular Ca2+.
Topics: Animals; Benzopyrans; Caffeine; Calcium; Calcium Channel Blockers; Cromakalim; Guanidines; Guanylate Cyclase; Histamine; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Norepinephrine; Pinacidil; Pyrroles; Rabbits; Renal Artery; Vasodilator Agents | 1989 |
Haemodynamic differences between cromakalim and pinacidil: comparison with nifedipine.
Topics: Animals; Benzopyrans; Blood Pressure; Cats; Cromakalim; Guanidines; Heart Rate; Hemodynamics; Male; Nifedipine; Pinacidil; Pyrroles; Renal Circulation; Renin | 1989 |
The negative inotropic effect of nicorandil is independent of cyclic GMP changes: a comparison with pinacidil and cromakalim in canine atrial muscle.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzopyrans; Cromakalim; Cyclic AMP; Cyclic GMP; Dogs; Female; Guanidines; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Tetraethylammonium Compounds; Vasodilator Agents | 1988 |
Relaxant effects of pinacidil, nicorandil, hydralazine and nifedipine as studied in the porcine coronary artery and guinea-pig taenia coli.
Topics: Animals; Caffeine; Colon; Coronary Vessels; Female; Guanidines; Guinea Pigs; Hydralazine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium; Swine; Vasodilator Agents | 1986 |
Similarity of relaxations evoked by BRL 34915, pinacidil and field-stimulation in rat oesophageal tunica muscularis mucosae.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Cromakalim; Electric Stimulation; Esophagus; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Rats; Rubidium Radioisotopes; Tetrodotoxin | 1988 |
[Pharmacological studies on pinacidil, a new antihypertensive agent. (3). Studies on the vasodilating effects in isolated monkey arteries and the peripheral hypotensive mechanism in SHR].
Topics: Animals; Antihypertensive Agents; Arteries; Guanidines; Heart Rate; Hydralazine; In Vitro Techniques; Macaca fascicularis; Nifedipine; Pinacidil; Rats; Rats, Inbred SHR; Stimulation, Chemical; Vasodilation | 1987 |
[Pharmacological studies on pinacidil, a new anti-hypertensive agent. 1. Antihypertensive effects in SHR and DOC/saline hypertensive rats].
Topics: Administration, Oral; Animals; Antihypertensive Agents; Desoxycorticosterone; Female; Guanidines; Hydralazine; Hypertension; Male; Nifedipine; Pinacidil; Rats; Rats, Inbred SHR; Sex Factors; Sodium Chloride | 1985 |
Comparison of the effects of a new vasodilator pinacidil and nifedipine on isolated blood vessels.
Topics: Adult; Aorta, Thoracic; Blood Vessels; Calcium; Calcium Radioisotopes; Female; Guanidines; Humans; Male; Middle Aged; Nifedipine; Norepinephrine; Pinacidil; Potassium; Pyridines; Vasodilator Agents | 1982 |
Comparison of in vitro effects of cicletanine, its enantiomers and major metabolite on rat thoracic aorta.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Calcium; Calcium Channels; Catecholamines; Guanidines; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Pinacidil; Potassium; Potassium Channels; Pyridines; Rats; Rats, Wistar; Stereoisomerism | 1993 |
A comparison of the inhibitory effects of sodium nitroprusside, pinacidil and nifedipine on pressor response to NG-nitro-L-arginine.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Guanidines; Heart Rate; Nifedipine; Nitroarginine; Nitroprusside; Norepinephrine; Pinacidil; Rats; Rats, Sprague-Dawley | 1993 |
Effects of potassium channel openers in isolated human cerebral arteries.
Topics: Benzopyrans; Calcium Channel Blockers; Carbachol; Cerebral Arteries; Cromakalim; Culture Techniques; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanidines; Humans; Iloprost; Nifedipine; Nimodipine; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1995 |
Comparison of the cellular electrophysiological characteristics of canine left ventricular epicardium, M cells, endocardium and Purkinje fibres.
Topics: Action Potentials; Animals; Antihypertensive Agents; Calcium Channel Blockers; Dogs; Electrophysiology; Endocardium; Female; Heart Rate; Male; Muscle Fibers, Skeletal; Nifedipine; Pericardium; Pinacidil; Purkinje Fibers; Tetrodotoxin; Ventricular Function, Left | 1998 |
Effect of 17beta-estradiol exposure on vasorelaxation induced by K(+) channel openers and Ca(2+) channel blockers.
Topics: Animals; Calcium Channel Blockers; Cromakalim; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; In Vitro Techniques; Male; Mesenteric Arteries; Nifedipine; Pinacidil; Potassium Channels; Progesterone; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents; Verapamil | 2002 |
Effects of L-type Ca(2+)-channel blockade, K(+)(ATP)-channel opening and nitric oxide on human uterine contractility in relation to gestational age and labour.
Topics: Adult; Arginine; Calcium Channel Blockers; Calcium Channels, L-Type; Female; Gestational Age; Humans; In Vitro Techniques; Labor, Obstetric; Magnesium; Myometrium; Nifedipine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxytocin; Pinacidil; Potassium Channels; Pregnancy; Uterine Contraction; Vasodilator Agents | 2003 |
Pacemaker potentials generated by interstitial cells of Cajal in the murine intestine.
Topics: Animals; Anti-Arrhythmia Agents; Biological Clocks; Caffeine; Calcium Channel Blockers; Central Nervous System Stimulants; Electrophysiology; Glyburide; In Vitro Techniques; Intestine, Small; Membrane Potentials; Mibefradil; Mice; Mice, Inbred BALB C; Myocytes, Smooth Muscle; Nifedipine; Pinacidil; Vasodilator Agents | 2005 |
Relaxant responses to calcium channel antagonists and potassium channel opener in human saphenous vein.
Topics: Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Membrane Potentials; Mibefradil; Muscle, Smooth, Vascular; Nifedipine; Pinacidil; Potassium Channels; Saphenous Vein; Vasodilation; Vasodilator Agents | 2006 |
Role of L-type calcium channels and PKC in active tone development in rabbit coronary artery.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcium Channel Blockers; Calcium Channels, L-Type; Carbazoles; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; In Vitro Techniques; Indoles; Male; Maleimides; Membrane Potentials; Nifedipine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phorbol 12,13-Dibutyrate; Pinacidil; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Vasoconstriction; Vasodilator Agents | 2007 |
K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro.
Topics: 4-Aminopyridine; Arachidonic Acids; Barium Compounds; Calcium Channel Blockers; Cell Differentiation; Cells, Cultured; Chlorides; Chorionic Gonadotropin; Cromakalim; Endocannabinoids; Female; Giant Cells; Humans; L-Lactate Dehydrogenase; Nifedipine; Pinacidil; Placenta; Polyunsaturated Alkamides; Potassium Channel Blockers; Potassium Channels; Pregnancy; Tetraethylammonium; Trophoblasts | 2008 |
Inhibition of uterine contractility with various tocolytics with and without progesterone: in vitro studies.
Topics: Adult; Female; Humans; Indomethacin; Magnesium Sulfate; Myometrium; Nifedipine; Obstetric Labor, Premature; Pinacidil; Pregnancy; Progesterone; Tocolytic Agents; Uterine Contraction | 2012 |
A protective role of Nox1/NADPH oxidase in a mouse model with hypoxia-induced bradycardia.
Topics: Action Potentials; Animals; Bradycardia; Calcium Channel Blockers; Disease Models, Animal; Electrocardiography; Heart Rate; Hypoxia; In Vitro Techniques; Membrane Transport Modulators; Mice, Inbred C57BL; Mice, Transgenic; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nifedipine; Pinacidil; Sinoatrial Block; Sinoatrial Node | 2015 |