nifedipine has been researched along with phenylephrine in 176 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 51 (28.98) | 18.7374 |
| 1990's | 76 (43.18) | 18.2507 |
| 2000's | 31 (17.61) | 29.6817 |
| 2010's | 17 (9.66) | 24.3611 |
| 2020's | 1 (0.57) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Allen, GS; Banghart, SB | 1 |
| Alvarez, JL; Vassort, G | 1 |
| Gurtu, S; Roychoudhary, AK; Seth, S | 1 |
| Donnelly, R; Elliott, HL; Howie, CA; Meredith, PA; Reid, JL | 1 |
| Leenen, FH; Yuan, B | 1 |
| Webber, SE; Widdicombe, JG; Woods, AJ; Yurdakos, E | 1 |
| Abernethy, DR; Andrawis, NS; Craft, N | 1 |
| Brieva, C; Penna, M; Pinardi, G; Vinet, R | 1 |
| Blaschke, TF; Ford, GA; Hoffman, BB; Katzir, D | 1 |
| Ito, K; Nishimura, K; Ota, M | 1 |
| Garcha, R; Hughes, A; Schachter, M; Sever, P; Thom, SM | 1 |
| Donnelly, R; Elliott, HL; Howie, CA; Reid, JL; Sumner, DJ | 1 |
| Christ, GJ; Maayani, S; Melman, A; Valcic, M | 1 |
| Kakishita, E; Sakamoto, K; Wakabayashi, I | 1 |
| Liepins, A; McWilliam, TM; Rankin, AJ | 1 |
| Hatake, K; Masui, H; Sakamoto, K; Wakabayashi, I; Yoshimoto, S | 1 |
| Brown, JH; Glembotski, CC; Irons, CE; McDonough, PM; Sei, CA; Sprenkle, AB | 1 |
| Azmy, SS; Grum, DF | 1 |
| Gong, MC; Kobayashi, S; Somlyo, AP; Somlyo, AV | 1 |
| Daniel, EE; Guan, YY; Kwan, CY | 3 |
| Glembotski, CC; Sei, CA | 1 |
| Czyrak, A; Maj, J; Mogilnicka, E; Siwanowicz, J | 1 |
| Blackmore, PF; Ratz, PH | 1 |
| Foglar, R; Hynie, S; Lincová, D; Wenke, M | 1 |
| Hatano, Y; Mori, K; Nakamura, K; Nishiwada, M; Park, JW; Yakushiji, T | 1 |
| Auclair, MC; Lechat, P; Vernimmen, C | 1 |
| Garthoff, B; Kazda, S; Knorr, A | 1 |
| Lindemann, JP | 1 |
| Armstead, WM; Hyman, AL; Kadowitz, PJ; Lippton, HL | 1 |
| Brooks, HL; Gross, GJ; Warltier, DC; Wynsen, JC | 2 |
| Agrawal, DK; McNeill, JH | 1 |
| MacLeod, KM | 1 |
| Auguet, M; Braquet, P; Chabrier, PE; Clostre, F; Delaflotte, S; Pirotzky, E | 1 |
| Brisac, AM; Lacolley, P; Laurent, S; Legrand, M; Schmitt, H; Tsoucaris-Kupfer, D | 1 |
| McMurtry, IF; O'Brien, RF; Rodman, DM; Yamaguchi, T | 1 |
| Auguet, M; Braquet, P; Clostre, F; Delaflotte, S; Pirotzky, E | 1 |
| Huang, BS; McCumbee, WD; Wright, GL | 1 |
| Baraka, A; Baroody, M; Haroun, S; Nawfal, M; Sibai, A | 1 |
| Ekenvall, L; Etzell, BM; Lindblad, LE | 1 |
| Feller, DR; Hamada, A; Miller, DD; Patil, PN; Shams, G; Venkataraman, BV | 1 |
| Bai, S; Kates, RA; Massagee, JT; McIntyre, RW; Reves, JG | 1 |
| Das, DK; Otani, H | 1 |
| Bauer, V; Rusko, J | 2 |
| Tohse, N | 1 |
| McGrath, JC | 1 |
| Alabaster, VA; Solca, AM | 1 |
| Flavahan, NA; Grant, TL; Marshall, RJ; McGrath, JC; O'Brien, JW | 1 |
| Demichel, P; Roquebert, J | 1 |
| Kannan, MS; Seip, AE | 1 |
| Hamilton, CA; Jardine, E; Reid, JL; Sumner, DJ | 1 |
| Hattori, Y; Kanno, M; Nakaya, H; Tohse, N | 1 |
| Cheung, WM; Falotico, R; Haertlein, B; Keiser, J; Tobia, A | 1 |
| Barrès, C; Cerutti, C; Morin, B; Sassard, J | 1 |
| Jandhyala, BS | 1 |
| Goldstein, DS; Haass, M; Kopin, IJ; Zukowska-Grojec, Z | 1 |
| Constantine, JW; Vatner, SF; Woodman, OL | 1 |
| Bozarth, JM; Chiu, AT; Timmermans, PB | 1 |
| Beckeringh, JJ; Thoolen, MJ; Timmermans, PB; Van Zwieten, PA | 1 |
| Eichler, HG; Gasic, S; Korn, A | 1 |
| Chan, KH; Chen, TS; Ho, CT; Lee, MC; Lee, TY; Wang, JH; Yang, MW | 1 |
| Chatterjee, M; Chiu, PJ; Sybertz, EJ; Tetzloff, G | 1 |
| Chow, R; Nebitko, RL; Zsotér, TT | 1 |
| Buckingham, RE | 1 |
| Farmer, S; Marshall, RJ; Martorana, M; Winslow, E | 1 |
| Amor, B; Degeorges, M; Foult, JM; Kahan, A; Menkes, CJ; Weber, S | 1 |
| Carrier, GO; Scarborough, NL | 1 |
| Distler, A; Fritschka, E; Kribben, A; Lenz, T; Philipp, T; Schudrowitsch, L | 1 |
| de Jonge, A; Kalkman, HO; Mathy, MJ; Thoolen, MJ; Timmermans, PB; van Meel, JC; van Zwieten, PA; Wilffert, B | 1 |
| Lues, I; Schümann, HJ | 1 |
| Su, CM; Swamy, VC; Triggle, DJ | 1 |
| Demichel, P; Gomond, P; Malek, A; Roquebert, J | 1 |
| Brochu, M; Roy, B; Sicotte, B; St-Louis, J | 1 |
| Drescher, P; Eckert, RE; Madsen, PO | 2 |
| Mizusawa, H; Omote, M | 3 |
| Antonaccio, MJ; Normandin, D | 1 |
| Drescher, P; Eckert, RE; Madsen, PO; Sparwasser, C | 1 |
| Bezstarosti, K; de Jonge, HW; Lamers, JM; van Heugten, HA | 1 |
| Danielsson, A; Karlsson, K; Lindström, P; Sehlin, J; Wu, J | 1 |
| Aleixandre, MA; Pintado, A; Puerro, M | 1 |
| Schwietert, R; van Zwieten, PA; Wilffert, B; Wilhelm, D | 1 |
| Drescher, P; Eckert, R; Madsen, PO; Sparwasser, C | 1 |
| Ma, YX; Yu, S; Zhao, HY | 1 |
| Ishiguro, S; Miyamoto, A; Nishio, A; Sakaguchi, H | 1 |
| Choi, KC; Kang, YJ; Kim, WJ; Lee, J; Park, JW; Woo, YJ; Yoo, KJ; Yoo, KS | 1 |
| Aston, N; Chess-Williams, R; Couldwell, C | 1 |
| Guh, JH; Ko, FN; Teng, CM | 1 |
| Ando, S; Endo, T; Imaizumi, T; Kubo, T; Shiramoto, M; Tagawa, T; Takeshita, A; Tokunaga, S | 1 |
| Andersen, LC; Clark, WA; LaPres, JJ; Rudnick, SJ | 1 |
| Chen, KM; Guan, YY; Sun, JJ | 1 |
| Nishio, A; Sakaguchi, H | 1 |
| Borycz, J; Bugajski, AJ; Bugajski, J; Gadek-Michalska, A | 1 |
| Ichihara, K; Mori, H; Nagasaka, M; Okumura, K | 1 |
| Baskakov, MR; Braque, P; Chabrier, EP; Markov, KhM; Medvedev, MA; Pinelis, VG; Storozhevykh, TP; Zagulova, DV | 1 |
| Campbell, PM; Forster, C | 1 |
| Ratz, PH | 1 |
| Daniel, EE; Kwan, CY; Low, AM | 1 |
| Guan, YY; Kwan, CY; Zheng, XF | 1 |
| Chapple, CR; Chess-Williams, R; Furukawa, K; Rosario, DJ; Smith, DJ; Uchiyama, T | 1 |
| Burt, RP; Chapple, CR; Marshall, I | 1 |
| Duling, BR; Xia, J | 1 |
| Chen, J; Chueh, SC; Guh, JH; Ko, FN; Lai, MK; Teng, CM | 1 |
| Dyer, DC; Nair, R | 1 |
| Elliott, J; Soydan, J | 1 |
| Brock, JA; McLachlan, EM; Rayner, SE | 1 |
| Harrer, JM; Kranias, EG; Lalli, J; Luo, W; Paul, RJ | 1 |
| Dora, KA; Doyle, MP; Duling, BR | 1 |
| Hattori, Y; Kanno, M; Nagashima, M; Tohse, N | 1 |
| Cheung, KK; Huang, Y | 1 |
| Kanonidis, I; Kokkas, B; Kotoula, M; Kouyoumtzis, A; Missopoulou, A; Myronidou, M; Papadopoulos, C; Paradelis, A; Sakadamis, G; Voulgaropoulos, C | 1 |
| Drescher, P; Eckert, R; Madsen, PO; Schmelz, HU; Sparwasser, C | 1 |
| Connolly, C; Docherty, JR; McCormick, PA | 1 |
| Fukao, M; Hattori, Y; Kanno, M; Kitabatake, A; Sakuma, I; Sato, A | 1 |
| Chan, NW; Huang, Y; Kwok, KH; Lau, CW | 1 |
| Edwards, FR; Hashitani, H | 1 |
| Lee, JM; Peuler, JD | 1 |
| Blaustein, MP; Mauban, JR; Miriel, VA; Wier, WG | 1 |
| Guh, JH; Hsieh, CH; Teng, CM | 1 |
| Docherty, JR; Honner, V | 1 |
| Bendhack, LM; Callera, GE | 1 |
| Mahmoudian, M; Mirkhani, H; Omrani, GR; Shafiei, M | 1 |
| Chan, EC; Pannangpetch, P; Woodman, OL | 1 |
| Eckert, RE; Karsten, AJ; Utz, J; Ziegler, M | 1 |
| Dora, KA; Garland, CJ; Hill, PB; Hughes, AD | 1 |
| Crépeau, V; Leblanc, N; Lupien, MA; Remillard, CV | 1 |
| Adachi, Y; Karaki, H; Satake, N; Sato, K; Shibata, S | 1 |
| Abacioğlu, N; Altuğ, S; Tunçtan, B; Uludağ, O | 1 |
| Leite, R; Webb, RC | 1 |
| Chen, CX; Kwan, CY | 1 |
| Chen, ZY; He, ZD; Huang, Y; Lau, CW; Wong, IY | 1 |
| Hill, MA; Potocnik, SJ | 1 |
| Eichinger, MR; Martin, HB; McCallum, M; Stofer, WD | 1 |
| Burt, RP | 1 |
| Cleary, L; Docherty, JR; Vandeputte, C | 1 |
| Ambrosio, SR; da Costa, FB; de Oliveira, AM; Tirapelli, CR | 1 |
| Bates, JN; Hoque, A; Lewis, SJ; Owen, JR | 1 |
| Kerry, Z; Ozer, A; Reel, B; Sevin, G; Yasa, M; Yetik Anacak, G | 1 |
| Broadley, KJ; Penson, PE | 1 |
| Arshad, M; Floyd, BC; Gupte, SA; Marks, B; Sarabu, MR; Vijay, V; Wolin, MS | 1 |
| Chan, KM; Hidaka, H; Hung, GH; Jones, RL; Lam, FF; Sasaki, Y; Suzuki, M | 1 |
| Cheng, J; Wang, YY; Wu, XL; Zhao, YY | 1 |
| Corti, R; Luscher, TF; Noll, G; Salvetti, A; Spieker, L; Sudano, I; Taddei, S; Virdis, A | 1 |
| Archer, SL; Bonnet, SN; Haromy, A; Harry, G; Hashimoto, K; Kajimoto, H; Michelakis, ED; Moudgil, R; Nakanishi, T; Rebeyka, I; Thébaud, B | 1 |
| Banach, K; Kapur, N | 1 |
| Kito, Y; Suzuki, H | 1 |
| Assreuy, AM; Criddle, DN; de Freitas Pires, A; Lima, RF; Soares, PM; Souza, EP | 1 |
| Prieto, D; Simonsen, U; Stankevicius, E; Villalba, N | 1 |
| Basak, F; Cehreli, SB; Cehreli, ZC; Guven, G; Kaya, E; Seyrek, M; Ulku, C; Vural, IM; Yildiz, O | 1 |
| Exintaris, B; Lang, RJ; Nguyen, DT | 1 |
| Adaramoye, OA; Almeida, MM; Anjos, RM; Araújo, IG; Cavalcante, KV; Medeiros, IA; Oliveira, AP; Oliveira, FA; Silvia, DF; Veras, RC | 1 |
| Chu, CC; Lin, MT; Shieh, JP; Wang, JJ | 1 |
| Chung, AW; Syyong, HT; van Breemen, C | 1 |
| Anderson, CP; Cole, JB; Engebretsen, KM; Holger, JS; Morgan, MW; Stellpflug, SJ | 1 |
| Canvasser, N; Clayman, RV; Louie, MK; McDougall, EM; Pick, DL; Shelkovnikov, S; Tongson-Ignacio, J | 1 |
| Brochu, M; Houde, V; Provencher, M; St-Louis, J | 1 |
| Deng, J; Jiang, HL; Li, J; Ma, S; Miao, LY; Xue, L; Zhang, Y; Zhu, J; Zhu, WL | 1 |
| Cupić, V; Gojković-Bukarica, L; Heinle, H; Ivković, B; Novaković, R; Vladimirov, S | 1 |
| Campos-Toimil, M; Cuíñas, A; Elíes, J; Orallo, F | 1 |
| Iwasaki, A; Payne, GW; Sellers, SL | 1 |
| Bertrand, PP; Grayson, TH; Leader, L; Murphy, TV; Sandow, SL; Senadheera, S; Tare, M | 1 |
| Fameli, N; Garcia-Alonso, M; Navarro-Dorado, J; Tejerina, T; van Breemen, C | 1 |
| Goto, K; Ishikawa, T; Saito, SY | 1 |
| Bu, Y; Chinannai, KS; Choi, HY; Ham, I; Kim, B; Kim, H; Lee, K | 1 |
| Panahi, N; Sargazi Zadeh, G | 1 |
| Hong, JM; Kim, J; Lee, SH; Ok, SH; Park, J; Shin, IW; Sohn, JT; Woo, MS | 1 |
| Hishinuma, E; Ishida, H; Ishikawa, T; Kitayama, T; Saito, SY | 1 |
| Dohi, N; Ishida, H; Ishikawa, T; Saito, SY | 1 |
| Alves, QL; Camargo, SB; Cechinel-Filho, V; Corrêa, R; da Hora, VRS; Jesus, AM; Medeiros, CFA; Moraes, RDA; Silva, DF; Stiz, DS | 1 |
2 trial(s) available for nifedipine and phenylephrine
| Article | Year |
|---|---|
Vascular pressor responses in treated and untreated essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Doxazosin; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Peptidyl-Dipeptidase A; Phenylephrine; Prazosin; Reflex; Regional Blood Flow; Renin | 1990 |
Chronic treatment with long-acting nifedipine reduces vasoconstriction to endothelin-1 in essential hypertension.
Topics: Acetylcholine; Adult; Brachial Artery; Calcium Channel Blockers; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelin-1; Female; Forearm; Humans; Hypercholesterolemia; Hypertension; Injections, Intra-Arterial; Male; Middle Aged; Nifedipine; Phenylephrine; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
174 other study(ies) available for nifedipine and phenylephrine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Cerebral arterial spasm: part 9. In vitro effects of nifedipine on serotonin-, phenylephrine-, and potassium-induced contractions of canine basilar and femoral arteries.
Topics: Animals; Basilar Artery; Calcium; Cerebral Arterial Diseases; Dogs; Dose-Response Relationship, Drug; Drug Antagonism; Female; Femoral Artery; In Vitro Techniques; Male; Nifedipine; Phenylephrine; Potassium; Pyridines; Serotonin; Spasm; Vasoconstriction | 1979 |
Properties of the low threshold Ca current in single frog atrial cardiomyocytes. A comparison with the high threshold Ca current.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Function; Barium; Cadmium; Calcium; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Heart Atria; Isoproterenol; Nickel; Nifedipine; Ouabain; Phenylephrine; Propranolol; Rana catesbeiana | 1992 |
Evidence for verapamil-induced functional inhibition of noradrenergic neurotransmission in vivo.
Topics: Adrenergic alpha-Agonists; Adrenergic Fibers; Animals; Cats; Electric Stimulation; Female; Ganglia, Sympathetic; Male; Muscle Contraction; Nictitating Membrane; Nifedipine; Phenoxybenzamine; Phenylephrine; Synaptic Transmission; Verapamil | 1992 |
Combination of nifedipine and doxazosin in essential hypertension.
Topics: Aged; Analysis of Variance; Angiotensin II; Antihypertensive Agents; Blood Pressure; Doxazosin; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Phenylephrine; Prazosin | 1992 |
Dietary sodium and the antihypertensive effect of nifedipine in spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Heart Ventricles; Hemodynamics; Hexamethonium Compounds; Hypertension; Male; Nifedipine; Organ Size; Phenylephrine; Rats; Rats, Inbred SHR; Sodium, Dietary; Sympathetic Nervous System | 1992 |
Effects of endothelin-1 on tracheal submucosal gland secretion and epithelial function in the ferret.
Topics: Albumins; Animals; Dose-Response Relationship, Drug; Endothelins; Epithelium; Ferrets; In Vitro Techniques; Membrane Potentials; Methacholine Chloride; Muramidase; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Pressure; Trachea | 1992 |
Calcium antagonists block angiotensin II-mediated vasoconstriction in humans: comparison with their effect on phenylephrine-induced vasoconstriction.
Topics: Adult; Angiotensin II; Diltiazem; Forearm; Humans; Infusions, Intravenous; Male; Nifedipine; Phenylephrine; Vascular Resistance; Vasoconstriction; Verapamil | 1992 |
Influence of extracellular Ca2+ on the modulation of alpha-adrenergic-induced contractions in rat aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Clonidine; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phenylephrine; Rats; Receptors, Adrenergic, alpha | 1991 |
Responsiveness of peripheral veins to vasodilators and the effect of nifedipine on alpha-adrenergic responsiveness in hypertension.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Dose-Response Relationship, Drug; Female; Hand; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Nifedipine; Norepinephrine; Phenylephrine; Receptors, Adrenergic, alpha; Vasodilator Agents; Veins | 1991 |
Existence of two components in the tonic contraction of rat aorta mediated by alpha 1-adrenoceptor activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Benzopyrans; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Carbamates; Cromakalim; In Vitro Techniques; Isoquinolines; Lanthanum; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Phenylcarbamates; Phenylephrine; Phosphatidylinositols; Piperazines; Protease Inhibitors; Pyrroles; Rats | 1991 |
Amlodipine inhibition of alpha-agonist induced contraction in human resistance vessels.
Topics: Adrenergic alpha-Agonists; Amlodipine; Azepines; Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nifedipine; Norepinephrine; Phenylephrine; Skin; Vasoconstriction | 1991 |
Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in alpha-adrenoceptor responsiveness with age and disease in isolated tissues.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Aged; Aged, 80 and over; Aging; Diabetes Complications; Erectile Dysfunction; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Penile Erection; Penis; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha | 1990 |
Potentiating effect of daunorubicin on vasocontractile responses to KCl and BAY K 8644 in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Clonidine; Daunorubicin; Drug Synergism; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains | 1990 |
Deuterium oxide reduces agonist and depolarization-induced contraction of rat aortic rings.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Calcium; Deuterium; Deuterium Oxide; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Water | 1990 |
Potentiating effect of NH4Cl on vasoconstriction in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Ammonium Chloride; Animals; Aorta, Thoracic; Drug Synergism; In Vitro Techniques; Kinetics; Male; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Vasoconstriction | 1991 |
The alpha-adrenergic stimulation of atrial natriuretic factor expression in cardiac myocytes requires calcium influx, protein kinase C, and calmodulin-regulated pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Atrial Natriuretic Factor; Calcium; Calmodulin; Cells, Cultured; Gene Expression; Heart; Hydrolysis; Isoquinolines; Myocardium; Nifedipine; Phenylephrine; Phosphatidylinositols; Piperazines; Protein Kinase C; Rats; Sulfonamides | 1991 |
Effect of chronic nifedipine therapy on the haemodynamic response to phenylephrine before and during halothane anaesthesia.
Topics: Adult; Anesthesia, Inhalation; Angina Pectoris; Coronary Artery Bypass; Female; Halothane; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Phenylephrine; Time Factors | 1992 |
Ca2+ channel blockers distinguish between G protein-coupled pharmacomechanical Ca2+ release and Ca2+ sensitization.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Egtazic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Portal Vein; Prazosin; Verapamil | 1991 |
Evidence against the role of alpha 1-adrenoceptor reserve in buffering the inhibitory effect of nifedipine on the contractility of canine vascular smooth muscle.
Topics: Animals; Calcium; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Endothelium; Extracellular Space; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenoxybenzamine; Phenylephrine; Receptors, Adrenergic, alpha; Saphenous Vein; Synapses; Time Factors | 1990 |
Calcium dependence of phenylephrine-, endothelin-, and potassium chloride-stimulated atrial natriuretic factor secretion from long term primary neonatal rat atrial cardiocytes.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Atrial Function; Atrial Natriuretic Factor; Calcium; Cells, Cultured; Egtazic Acid; Endothelins; Endothelium, Vascular; Heart; Heart Atria; Kinetics; Nifedipine; Peptides; Phenylephrine; Pituitary Neoplasms; Potassium Chloride; Rats; Rats, Inbred Strains | 1990 |
Some behavioral effects of repeated administration of calcium channel antagonists.
Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Diltiazem; Exploratory Behavior; Male; Nifedipine; Nimodipine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1990 |
Differential activation of rabbit femoral arteries by aluminum fluoride and sodium fluoride.
Topics: Aluminum; Aluminum Compounds; Animals; Calcium Channels; Drug Interactions; Enzyme Activation; Female; Femoral Artery; Fluorides; In Vitro Techniques; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Rabbits; Sodium Fluoride; Type C Phospholipases; Vasoconstriction | 1990 |
[Closer characterization of alpha-receptor subpopulations in the smooth muscle of the splenic capsule in rats].
Topics: Animals; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Phenoxybenzamine; Phenylephrine; Rats; Receptors, Adrenergic, alpha; Spleen; Yohimbine | 1990 |
Effects of thiobarbiturates on smooth muscle reactivity in isolated aortas from spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Species Specificity; Thiamylal; Thiopental | 1990 |
[Effect of substances modifying calcium movement on the contractility of cultured cardiac cells].
Topics: Animals; Caffeine; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Histamine; Imipramine; Ion Channels; Isoproterenol; Myocardial Contraction; Nifedipine; Phenylephrine; Rats; Verapamil | 1985 |
Interference of the calcium antagonist nisoldipine with the abnormal response of vessels from hypertensive rats to alpha-adrenergic stimulation.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nisoldipine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 1985 |
Alpha-adrenergic stimulation of sarcolemmal protein phosphorylation and slow responses in intact myocardium.
Topics: Animals; Calcium; Calcium-Binding Proteins; Ion Channels; Isoproterenol; Kinetics; Male; Myocardial Contraction; Myocardium; Nifedipine; Phenylephrine; Phosphoproteins; Phosphorylation; Potassium; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sarcolemma; Sodium | 1986 |
Influence of nisoldipine on vascular resistance and vasoconstrictor responses in cats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Azepines; Blood Pressure; Brimonidine Tartrate; Cardiac Output; Cats; Dinoprost; Dioxanes; Electric Stimulation; Female; Idazoxan; Male; Methoxamine; Nifedipine; Nisoldipine; Norepinephrine; Phenylephrine; Prostaglandin Endoperoxides, Synthetic; Prostaglandins F; Quinoxalines; Splanchnic Circulation; Sulfonamides; Sympathetic Nervous System; Tyramine; Vascular Resistance; Vasoconstriction | 1987 |
Changes in adrenergic pressor responses by calcium channel modulation in conscious dogs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine Derivatives; Azepines; Calcium; Dogs; Female; Hemodynamics; Hexamethonium; Hexamethonium Compounds; Ion Channels; Male; Nifedipine; Phenylephrine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Angiotensin; Receptors, Vasopressin; Vasopressins | 1987 |
Vascular responses to agonists in rat mesenteric artery from diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Diabetes Mellitus, Experimental; In Vitro Techniques; Isometric Contraction; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phenylephrine; Potassium; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Adrenergic-cholinergic interactions in left atria. II. Comparison of the antagonism of inotropic responses to alpha- and beta-adrenoceptor stimulation and BAY K 8644 by carbachol, D-600, and nifedipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Chloride; Carbachol; Gallopamil; Isoproterenol; Myocardial Contraction; Nifedipine; Phenylephrine; Rabbits | 1987 |
Endothelin and Ca++ agonist Bay K 8644: different vasoconstrictive properties.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Aorta, Thoracic; Calcium; Carbachol; Diltiazem; Egtazic Acid; Endothelins; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Peptides; Phenylephrine; Rats; Rats, Inbred Strains; Reference Values; Vasoconstrictor Agents | 1988 |
[Central control of the baroreflex response to phenylephrine by dihydropyridines in the anesthetized rat].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium; Calcium Channels; Dihydropyridines; Heart Rate; Hypertension; Nifedipine; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Nicotinic; Sympathetic Nervous System | 1988 |
Hypoxic contraction of isolated rat pulmonary artery.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Cold Temperature; Endothelium, Vascular; In Vitro Techniques; Male; Meclofenamic Acid; Nifedipine; Oxygen; Phenylephrine; Pulmonary Artery; Rats; Rats, Inbred Strains; Vasoconstriction | 1989 |
Effects of atrial natriuretic factor (ANF) on phenylephrine-triggered intra- and extracellular calcium dependent contraction in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Calcium; Colforsin; Cyclic AMP; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Rats; Rats, Inbred Strains | 1989 |
Further investigation of a potential calcium channel modulator isolated from rat erythrocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Calcium; Calcium Channels; Erythrocytes; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Peptides; Phenylephrine; Potassium; Rats; Rats, Inbred Strains | 1989 |
Effects of preoperative calcium channel and beta-adrenergic blockade on the vascular response to adrenergic agonists during cardiopulmonary bypass.
Topics: Adult; Arteries; Blood Pressure; Blood Volume; Cardiopulmonary Bypass; Coronary Artery Bypass; Humans; Isoproterenol; Middle Aged; Nifedipine; Norepinephrine; Phenylephrine; Preoperative Care; Propranolol; Vascular Resistance; Veins | 1989 |
Nifedipine and alpha-adrenoceptor function in human finger skin vessels.
Topics: Adult; Azepines; Fingers; Humans; Male; Nifedipine; Phenylephrine; Receptors, Adrenergic, alpha; Regional Blood Flow; Skin; Vasoconstriction | 1989 |
Does in vitro activation of postsynaptic alpha 2-adrenoceptor utilize intracellular Ca2+ for contraction in dog saphenous vein?
Topics: Animals; Azepines; Calcium; Dogs; Egtazic Acid; HEPES; In Vitro Techniques; Manganese; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Yohimbine | 1989 |
Paradoxical effects of isothiocyanate analog of tolazoline on rat aorta and human platelets.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Atrial Function; Benzazepines; Blood Platelets; Calcium; Carbachol; Dose-Response Relationship, Drug; Epinephrine; Female; Guinea Pigs; Heart Atria; Isoproterenol; Isothiocyanates; Male; Nifedipine; Phenoxybenzamine; Phentolamine; Phenylephrine; Platelet Activation; Platelet Aggregation; Prazosin; Rats; Rats, Inbred Strains; Temperature; Thiocyanates; Tolazoline; Trachea; Vasoconstriction; Verapamil; Yohimbine | 1989 |
Effects of preoperative calcium entry blocker therapy on alpha-adrenergic responsiveness in patients undergoing coronary revascularization.
Topics: Adult; Aged; Calcium Channel Blockers; Coronary Artery Bypass; Diltiazem; Epinephrine; Humans; Middle Aged; Nifedipine; Norepinephrine; Phenylephrine; Preoperative Care; Receptors, Adrenergic, alpha; Vascular Resistance | 1987 |
Alpha 1-adrenoceptor-mediated phosphoinositide breakdown and inotropic response in rat left ventricular papillary muscles.
Topics: 2,3-Diphosphoglycerate; Animals; Diphosphoglyceric Acids; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Male; Manganese; Myocardial Contraction; Myocardium; Neomycin; Nifedipine; Phenylephrine; Phorbol Esters; Phosphatidylinositols; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1988 |
Calcium and the activation of the alpha 1-adrenoceptors in the guinea-pig taenia caeci.
Topics: Animals; Calcium; Cecum; Epinephrine; Guinea Pigs; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth; Nifedipine; Phenylephrine; Phorbol Esters; Receptors, Adrenergic, alpha | 1988 |
[Analysis of membrane current system involved in the inotropic effects mediated by alpha-adrenoceptors in the heart].
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Myocardial Contraction; Nifedipine; Phenylephrine; Prazosin; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1988 |
alpha-Adrenoceptor agonists and the Ca2+-dependence of smooth muscle contraction: evidence for subtypes of receptors or for agonist-dependent differences in the agonist-receptor interaction?
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Clonidine; Ethanolamines; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Xylazine | 1985 |
Lack of differential inhibition by nifedipine of pressor responses induced by alpha 1- and alpha 2-adrenoceptor agonists and by angiotensin II in anaesthetized cats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Blood Pressure; Cats; Doxazosin; Male; Muscle, Smooth, Vascular; Nifedipine; Nordefrin; Phenylephrine; Prazosin; Vasoconstriction; Yohimbine | 1985 |
Influence of blood gases, Ca2+-entry blockade and angiotensin converting enzyme inhibition on pressor responses to alpha-adrenoceptor agonists: evidence in vivo for subtypes of response independent of receptor subtype?
Topics: Adrenergic alpha-Agonists; Animals; Carbon Dioxide; Ethanolamines; Male; Nifedipine; Oligopeptides; Oxygen; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred Strains; Teprotide; Time Factors; Vasoconstriction; Xylazine | 1985 |
Alpha-adrenergic agonist and antagonist activity of dihydroergotoxine in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Dihydroergotoxine; Electric Stimulation; Heart Rate; Hemodynamics; Male; Methysergide; Nifedipine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine | 1985 |
Mechanisms of alpha-adrenoceptor mediated contractions of rat mesenteric artery.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Clonidine; In Vitro Techniques; Kinetics; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction; Verapamil | 1986 |
Differential effects of nifedipine, nicorandil and nitroglycerin on the pressor responses elicited by selective alpha-1 and alpha-adrenoceptor agonists in conscious dogs.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Dogs; Female; Hemodynamics; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Phenylephrine; Vasodilator Agents | 1987 |
The effects of calcium antagonists on blood pressure and responses to alpha-adrenoceptor agonists in hypertensive rabbits.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Drug Interactions; Hemodynamics; Hypertension, Renal; Male; Nifedipine; Nordefrin; Phenylephrine; Rabbits; Verapamil | 1987 |
Effects of alpha-adrenoceptor stimulation on electrophysiological properties and mechanics in rat papillary muscle.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Barium; Female; In Vitro Techniques; Male; Membrane Potentials; Myocardial Contraction; Nifedipine; Phenylephrine; Rats; Rats, Inbred Strains | 1987 |
Increased vasodilator responsiveness to BRL 34915 in spontaneously hypertensive versus normotensive rats: contrast with nifedipine.
Topics: Animals; Antihypertensive Agents; Aorta; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Pyrroles; Rats; Rats, Inbred SHR; Vascular Resistance; Vasodilation | 1989 |
Cardiovascular effects of two new calcium antagonists, PY 108-068 and PN 200-110, in conscious spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Isradipine; Male; Nifedipine; Nitroglycerin; Oxadiazoles; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Reflex | 1988 |
Studies on the effects of felodipine on the vascular resistance and reactivity in pentobarbital anesthetized dogs.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Denervation; Dogs; Extremities; Felodipine; Female; Imidazoles; Male; Nifedipine; Norepinephrine; Pentobarbital; Phenylephrine; Receptors, Adrenergic, alpha; Vascular Resistance; Vasoconstriction | 1985 |
Differential inhibition of alpha adrenoceptor-mediated pressor responses by rat atrial natriuretic peptide in the pithed rat.
Topics: Adrenergic alpha-Antagonists; Animals; Atrial Natriuretic Factor; Blood Pressure; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Male; Nifedipine; Nitroprusside; Phenylephrine; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Nifedipine attenuates both alpha-1 and alpha-2 adrenoceptor-mediated pressor and vasoconstrictor responses in conscious dogs and primates.
Topics: Animals; Azepines; Blood Pressure; Cardiac Output; Dogs; Female; Heart Rate; Macaca mulatta; Male; Methoxamine; Nifedipine; Norepinephrine; Phenylephrine; Receptors, Adrenergic, alpha; Vascular Resistance; Vasoconstriction | 1986 |
Relationship between phosphatidylinositol turnover and Ca++ mobilization induced by alpha-1 adrenoceptor stimulation in the rat aorta.
Topics: Animals; Aorta; Calcium; Dose-Response Relationship, Drug; Inositol Phosphates; Male; Nifedipine; Norepinephrine; Phenylephrine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1987 |
Sensitivity of alpha-1 adrenoceptor-mediated pressor responses to inhibition by Ca++ entry blockers in the pithed rat: arguments against the role of receptor reserve.
Topics: Animals; Blood Pressure; Decerebrate State; Diastole; Male; Nifedipine; Phenoxybenzamine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1987 |
Nifedipine antagonizes alpha-adrenoceptor mediated splanchnic and systemic vasoconstriction in man.
Topics: Adult; Hemodynamics; Humans; Male; Nifedipine; Phenylephrine; Receptors, Adrenergic, alpha; Splanchnic Circulation; Vasoconstriction | 1987 |
The effects of EGTA on vascular smooth muscle contractility in calcium-free medium.
Topics: Animals; Calcium; Culture Media; Dogs; Egtazic Acid; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Prazosin; Time Factors; Yohimbine | 1988 |
The inhibitory effects of nifedipine and fentanyl on circulatory response during laryngoscopy and intubation in patients pretreated with neosynephrine eye drops for mydriasis.
Topics: Female; Fentanyl; Hemodynamics; Humans; Hypertension; Intubation, Intratracheal; Laryngoscopy; Male; Middle Aged; Mydriatics; Nifedipine; Ophthalmologic Surgical Procedures; Phenylephrine | 1988 |
Phorbol 12,13-dibutyrate, an activator of protein kinase C, stimulates both contraction and Ca2+ fluxes in dog saphenous vein.
Topics: Animals; Calcium; Dogs; Enzyme Activation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Saphenous Vein | 1988 |
The effect of verapamil, diltiazem and nifedipine on baroreceptor reflexes.
Topics: Animals; Atropine; Blood Pressure; Diltiazem; Heart Rate; Male; Nifedipine; Phenylephrine; Pressoreceptors; Propranolol; Rats; Rats, Inbred Strains; Reflex; Verapamil | 1988 |
Studies on the anti-vasoconstrictor activity of BRL 34915 in spontaneously hypertensive rats; a comparison with nifedipine.
Topics: Angiotensin II; Animals; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Female; Hypertension; Infusions, Intravenous; Nifedipine; Norepinephrine; Phenylephrine; Pyrroles; Rats; Rats, Inbred SHR; Vasoconstriction; Vasopressins | 1988 |
Effect of calcium entry blockade on the actions of phenylephrine on the taenia of the guinea pig caecum.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Cecum; Electric Stimulation; Evoked Potentials; Guinea Pigs; Humans; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitroprusside; Phenylephrine; Potassium; Procaine; Verapamil | 1988 |
The effects of bepridil compared with calcium antagonists on rat and rabbit aorta.
Topics: Animals; Aorta, Thoracic; Bepridil; Calcium Channel Blockers; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nisoldipine; Phenylephrine; Potassium; Pyrrolidines; Rabbits; Rats; Species Specificity | 1986 |
Nifedipine and alpha 1-adrenergic blockade in Raynaud's phenomenon.
Topics: Adult; Blood Pressure; Double-Blind Method; Female; Humans; Male; Nifedipine; Phenylephrine; Prazosin; Raynaud Disease | 1985 |
Nifedipine and alpha adrenoceptors in rat aorta. I. Role of extracellular calcium in alpha-1 and alpha-2 adrenoceptor-mediated contraction.
Topics: Animals; Aorta; Calcium; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1984 |
Effect of nifedipine and verapamil on alpha-receptor-activation in patients with essential hypertension.
Topics: Adult; Aged; Blood Platelets; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Phenylephrine; Pressoreceptors; Receptors, Adrenergic, alpha; Verapamil; Yohimbine | 1984 |
Differential effect of calcium entry blockers on alpha 1-adrenoceptor-mediated vasoconstriction in vivo.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Calcium Channel Blockers; Catecholamines; Clonidine; Ethanolamines; Imidazoles; Imidazolines; Male; Methoxamine; Nifedipine; Phenylephrine; Rats; Rats, Inbred Strains; Vasoconstriction; Verapamil | 1983 |
B-HT 920 acts as an alpha 1-adrenoceptor agonist in the rabbit aorta under certain in vitro conditions.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Aorta, Thoracic; Azepines; Calcium; Female; In Vitro Techniques; Ion Channels; Male; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Phenylephrine; Rabbits; Reserpine; Yohimbine | 1984 |
Calcium channel activation in vascular smooth muscle by BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Azepines; Calcium; Drug Synergism; In Vitro Techniques; Ion Channels; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium; Rats; Rats, Inbred WKY | 1984 |
Effect of dihydroergocristine on blood pressure and activity at peripheral alpha-adrenoceptors in pithed rats.
Topics: Animals; Blood Pressure; Decerebrate State; Dihydroergotoxine; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Male; Nifedipine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine | 1984 |
Effects of nifedipine and Bay K 8644 on myotropic responses in aortic rings of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Kinetics; Muscle Contraction; Nifedipine; Nitrendipine; Phenylephrine; Potassium Chloride; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tritium | 1995 |
Role of intracellular Ca2+ stores in smooth muscle contractions of the guinea pig vas deferens.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channels; Guinea Pigs; Humans; In Vitro Techniques; Intracellular Fluid; Male; Models, Biological; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Prazosin; Prostatic Hyperplasia; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Vas Deferens | 1993 |
Phenylephrine-induced rhythmic activity in the rabbit ear artery.
Topics: Animals; Arginine; Arteries; Charybdotoxin; Ear, External; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Male; Nifedipine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Periodicity; Phenylephrine; Potassium Channel Blockers; Prostaglandin Antagonists; Rabbits; Scorpion Venoms; Vasoconstriction | 1993 |
Effects of cyclopiazonic acid on phenylephrine-induced contractions in the rabbit ear artery.
Topics: Animals; Arteries; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Charybdotoxin; Dihydropyridines; Ear; Electrophysiology; Endothelium, Vascular; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium Channel Blockers; Rabbits; Sarcoplasmic Reticulum; Scorpion Venoms | 1994 |
Role of Ca2+ in the vascular contraction caused by a thrombin receptor activating peptide.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Animals; Aorta, Thoracic; Calcium; Endothelium, Vascular; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Peptide Fragments; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Thrombin | 1994 |
Alpha-1 receptor mediated smooth muscle regulation in benign prostatic hyperplasia.
Topics: Adrenergic alpha-Antagonists; Calcium; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Male; Muscle, Smooth; Nifedipine; Phenylephrine; Phosphodiesterase Inhibitors; Prostatic Hyperplasia; Receptors, Adrenergic, alpha | 1994 |
G-proteins in alpha 1-adrenoceptor mediated prostatic smooth muscle contraction.
Topics: Adrenergic alpha-Antagonists; GTP-Binding Proteins; Humans; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Pertussis Toxin; Phenylephrine; Potassium; Prostate; Prostatic Hyperplasia; Receptors, Adrenergic, alpha; Signal Transduction; Virulence Factors, Bordetella | 1994 |
Calcium and the endothelin-1 and alpha 1-adrenergic stimulated phosphatidylinositol cycle in cultured rat cardiomyocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Calcimycin; Calcium; Calcium Channels; Cells, Cultured; Egtazic Acid; Endothelins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heart; Inositol Phosphates; Intracellular Fluid; Membrane Lipids; Muscle Proteins; Myocardium; Nifedipine; Ouabain; Phenylephrine; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Potassium; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Signal Transduction; Stimulation, Chemical | 1994 |
Protective effects of calcium channel blockers on acute bromobenzene toxicity to isolated rat hepatocytes. Inhibition of phenylephrine-induced calcium oscillations.
Topics: Animals; Bromobenzenes; Calcium; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Egtazic Acid; Female; L-Lactate Dehydrogenase; Liver; Nifedipine; Phenylephrine; Rats; Rats, Sprague-Dawley; Verapamil | 1995 |
A comparison of the effects of TMB-8 and nifedipine on pressor responses to alpha 1- and alpha 2-adrenoceptor agonists in pithed rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Animals; Azepines; Blood Pressure; Dose-Response Relationship, Drug; Gallic Acid; Injections, Intravenous; Male; Methoxamine; Nifedipine; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 | 1995 |
Functional study on the effects of nifedipine, cromakalim, and the absence of extracellular Ca2+ on alpha 1-adrenoceptor-mediated excitation-contraction coupling in isolated rat portal vein: comparison with depolarization-mediated excitation-contraction c
Topics: Animals; Benzopyrans; Calcium; Calcium Channel Blockers; Cromakalim; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Parasympatholytics; Phenylephrine; Portal Vein; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1993 |
Ryanodine-sensitive intracellular Ca2+ stores in isolated rabbit penile erectile tissue.
Topics: Animals; Caffeine; Calcium; Electric Stimulation; In Vitro Techniques; Intracellular Membranes; Male; Nifedipine; Penile Erection; Penis; Phenylephrine; Potassium; Rabbits; Ryanodine; Solutions | 1995 |
Effects of isoprenaline, phenylephrine on heart and influence of nifedipine on these effects.
Topics: Animals; Calcium Channels; Female; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nifedipine; Phenylephrine; Rats; Rats, Sprague-Dawley | 1994 |
Enhanced contractile response to phenylephrine and increased density of [3H]PN200-110 binding sites in thoracic aorta isolated from dietary magnesium-deficient rats.
Topics: Animals; Aorta, Thoracic; Calcium Channels; Diet; Endothelium, Vascular; Isradipine; Magnesium Deficiency; Male; Muscle Contraction; Nifedipine; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1994 |
Impairement of endothelium-dependent relaxation in chronic two-kidney, one clip hypertensive rats.
Topics: Acetylcholine; Animals; Constriction; Disease Models, Animal; Hypertension; In Vitro Techniques; Male; Nifedipine; Nitric Oxide; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1994 |
Alpha 1A-adrenoceptor subtype mediates contraction of the rat urethra.
Topics: Aminoquinolines; Animals; Calcium; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Tetrahydroisoquinolines; Urethra | 1994 |
Functional identification of alpha 1-adrenoceptor subtypes in human prostate: comparison with those in rat vas deferens and spleen.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens | 1994 |
Effects of a novel dihydropyridine calcium antagonist on venous capacitance in Wistar-Kyoto rats.
Topics: Animals; Blood Pressure; Blood Volume; Calcium Channel Blockers; Drug Interactions; Ethanol; Hemodynamics; Hexamethonium Compounds; Male; Niacinamide; Nifedipine; Nitroglycerin; Phenylephrine; Rats; Rats, Inbred WKY; Sympathectomy, Chemical; Vascular Resistance | 1994 |
Myosin heavy chain synthesis is independently regulated in hypertrophy and atrophy of isolated adult cardiac myocytes.
Topics: Actins; Animals; Atrophy; Calcium Channels; Cats; Cells, Cultured; Desmin; Gene Expression Regulation; Hypertrophy; Isoproterenol; Muscle Contraction; Myocardium; Myofibrils; Myosins; Nifedipine; Phenylephrine | 1994 |
Effects of direct lytic factors from southern Chinese cobra venom on Ca2+ movement in rabbit aorta strip.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cobra Cardiotoxin Proteins; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Procaine; Rabbits; Verapamil | 1993 |
Mechanisms of the enhanced contractile response to phenylephrine in thoracic aorta isolated from rats with dietary magnesium deficiency.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta, Thoracic; Diet; In Vitro Techniques; Isoquinolines; Isradipine; Magnesium Deficiency; Male; Nifedipine; Phenylephrine; Piperazines; Potassium Chloride; Rats; Rats, Wistar; Vasoconstriction | 1994 |
Calcium channel blockers impair the pituitary-adrenocortical responses to central adrenergic receptors stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Clonidine; Corticosterone; Drug Interactions; Hypothalamo-Hypophyseal System; Isoproterenol; Male; Nifedipine; Phenylephrine; Pituitary-Adrenal System; Rats; Rats, Wistar; Stimulation, Chemical; Verapamil | 1993 |
Effects of MPC-1304, a novel Ca2+ entry blocker, on alpha-adrenoceptor-mediated pressor responses in pithed rats.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Brimonidine Tartrate; Calcium Channel Blockers; Decerebrate State; Dihydropyridines; Electric Stimulation; Nifedipine; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Spinal Cord; Sympathetic Nervous System | 1993 |
[The role of extracellular calcium in the vasoconstriction evoked by endothelin-1].
Topics: Animals; Calcium; Calcium Channels; Endothelins; Endothelium, Vascular; In Vitro Techniques; Meglumine; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Rats; Rats, Wistar; Vasoconstriction | 1993 |
The role of sarcoplasmic reticulum in endothelium-dependent and endothelium-independent rhythmic contractions in the rabbit mesenteric artery.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Endothelium, Vascular; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Rabbits; Ryanodine; Sarcoplasmic Reticulum; Sparteine | 1993 |
Nifedipine inhibits responses to alpha-adrenoceptor stimulation in canine blood vessels: impact of heart failure.
Topics: Animals; Azepines; Cardiac Output, Low; Dogs; Male; Nifedipine; Norepinephrine; Phenylephrine; Receptors, Adrenergic, alpha; Vasoconstriction | 1993 |
High alpha 1-adrenoceptor occupancy decreases relaxing potency of nifedipine by increasing myosin light chain phosphorylation.
Topics: Animals; Calcium; In Vitro Techniques; Myosins; Nifedipine; Phenylephrine; Phosphorylation; Rabbits; Receptors, Adrenergic, alpha; Renal Artery; Type C Phospholipases; Vasodilation | 1993 |
Functional alterations in the aorta of the spontaneously hypertensive rat: pharmacological assessment with cyclopiazonic acid.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channels; Endoplasmic Reticulum; Hypertension; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
Cyclopiazonic acid causes endothelium-dependent relaxation in rat aorta.
Topics: Acetylcholine; Animals; Aorta; Calcium-Transporting ATPases; Endothelium, Vascular; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Phenylephrine; Rats; Rats, Wistar | 1993 |
Alpha 1A-adrenoceptor-mediated contractile responses of the human vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Binding, Competitive; Calcium; Clonidine; Extracellular Space; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Vas Deferens | 1995 |
The role of capacitative Ca2+ influx in the alpha 1B-adrenoceptor-mediated contraction to phenylephrine of the rat spleen.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Calcium; Calcium Channel Blockers; Enzyme Inhibitors; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Nifedipine; Phenylephrine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Spleen | 1995 |
Electromechanical coupling and the conducted vasomotor response.
Topics: Animals; Cheek; Cricetinae; Electric Conductivity; Electrophysiology; In Vitro Techniques; Male; Membrane Potentials; Mesocricetus; Models, Cardiovascular; Nifedipine; Phenylephrine; Potassium Chloride; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 1995 |
Inhibition by tamsulosin of tension responses of human hyperplastic prostate to electrical field stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aged; Calcium Channel Blockers; Electric Stimulation; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Phenylephrine; Potassium; Prazosin; Prostate; Prostatic Hyperplasia; Sulfonamides; Tamsulosin | 1996 |
Pharmacological characterization of alpha 1-adrenoceptors in porcine uterine artery.
Topics: Animals; Arteries; Calcium; Clonidine; Estrus; Female; In Vitro Techniques; Nifedipine; Norepinephrine; Phenylephrine; Pregnancy; Pregnancy, Animal; Receptors, Adrenergic, alpha-1; Swine; Uterus | 1996 |
Characterisation of beta-adrenoceptors in equine digital veins: implications of the modes of vasodilatory action of isoxsuprine.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Azepines; Blood Vessels; Dose-Response Relationship, Drug; Fenoterol; Horses; Isoproterenol; Isoxsuprine; Methoxamine; Nifedipine; Norepinephrine; Phenylephrine; Propanolamines; Receptors, Adrenergic, beta; Vasoconstriction; Vasodilation; Veins | 1995 |
Contribution of alpha-adrenoceptors to depolarization and contraction evoked by continuous asynchronous sympathetic nerve activity in rat tail artery.
Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Calcium Channel Blockers; Ciguatoxins; Female; Idazoxan; Membrane Potentials; Muscle Contraction; Nifedipine; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic, alpha; Tail | 1997 |
Targeted ablation of the phospholamban gene is associated with a marked decrease in sensitivity in aortic smooth muscle.
Topics: Animals; Aorta; Blotting, Western; Calcium-Binding Proteins; Calcium-Transporting ATPases; Enzyme Inhibitors; In Vitro Techniques; Indoles; Mice; Mice, Inbred C3H; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium Chloride; Sarcoplasmic Reticulum; Time Factors | 1997 |
Elevation of intracellular calcium in smooth muscle causes endothelial cell generation of NO in arterioles.
Topics: Acetylcholine; Aniline Compounds; Animals; Arterioles; Calcium; Cricetinae; Endothelium, Vascular; Kinetics; Male; Mesocricetus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Phenylephrine; Potassium Chloride; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents; Xanthenes | 1997 |
Alpha 1-adrenoceptor subtype involved in the positive and negative inotropic responses to phenylephrine in rat papillary muscle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Carcinogens; Cardiotonic Agents; Clonidine; Dioxanes; Electrophysiology; In Vitro Techniques; Myocardial Contraction; Nifedipine; Papillary Muscles; Phenylephrine; Phorbol 12,13-Dibutyrate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1997 |
Endothelium-dependent rhythmic contractions induced by cyclopiazonic acid in rat mesenteric artery.
Topics: Animals; Calcium Channel Blockers; Endothelium, Vascular; Enzyme Inhibitors; Indoles; Indomethacin; Mesenteric Arteries; Muscle Contraction; Nifedipine; Nitroarginine; Phenylephrine; Potassium Channels; Rats; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
Clonidine and vasomotion physiology.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Calcium; Cattle; Clonidine; Drug Synergism; In Vitro Techniques; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Yohimbine | 1998 |
Role of intracellular Ca2+ stores in smooth muscle of human penile erectile tissue.
Topics: Animals; Caffeine; Calcium; Electric Stimulation; Erectile Dysfunction; Humans; In Vitro Techniques; Intracellular Fluid; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Penis; Phenylephrine; Rabbits; Ryanodine | 1998 |
Effects of the selective cyclooxygenase-2 inhibitor nimesulide on vascular contractions in endothelium-denuded rat aorta.
Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Clonidine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelin-1; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Muscle Contraction; Nifedipine; Phenylephrine; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides | 1998 |
A role of myofilament Ca2+ sensitivity in enhanced vascular reactivity in cardiomyopathic hamsters.
Topics: Actin Cytoskeleton; Angiotensin II; Animals; Aorta; Calcium; Calcium Channel Blockers; Cardiomyopathies; Cricetinae; Indoles; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Nifedipine; Phenylephrine; Phorbol 12,13-Dibutyrate; Potassium; Ryanodine; Staurosporine; Vasoconstrictor Agents | 1998 |
Contractile and relaxant effects of tetrapentylammonium ions in rat isolated mesenteric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium Channel Blockers; Endothelin-1; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Verapamil | 1998 |
Spontaneous and neurally activated depolarizations in smooth muscle cells of the guinea-pig urethra.
Topics: Adenosine Triphosphate; Animals; Caffeine; Egtazic Acid; Electric Stimulation; Evoked Potentials; Female; Guanethidine; Guinea Pigs; In Vitro Techniques; Indoles; Membrane Potentials; Microelectrodes; Muscle, Smooth; Neuromuscular Junction; Nifedipine; Niflumic Acid; Phenylephrine; Stochastic Processes; Synaptic Transmission; Tetrodotoxin; Urethra | 1999 |
Acute vasorelaxant effects of metformin and attenuation by stimulation of sympathetic agonist release.
Topics: Adrenergic Agonists; Animals; Arginine Vasopressin; Arteries; Female; In Vitro Techniques; Metformin; Nerve Endings; Nifedipine; Nitroprusside; Norepinephrine; Oxidopamine; Phenylephrine; Rats; Rats, Sprague-Dawley; Serotonin; Sympathomimetics; Tail; Vasoconstriction; Vasodilation; Vasodilator Agents | 1999 |
Local and cellular Ca2+ transients in smooth muscle of pressurized rat resistance arteries during myogenic and agonist stimulation.
Topics: Adrenergic alpha-Agonists; Animals; Arteries; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Fluorescent Dyes; In Vitro Techniques; Indoles; Male; Microscopy, Confocal; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Stimulation, Chemical; Vascular Resistance; Vasoconstriction; Vasodilator Agents | 1999 |
Investigation of the effects of some alkaloidal alpha1-adrenoceptor antagonists on human hyperplastic prostate.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Alkaloids; Animals; Aporphines; Berberine; Berberine Alkaloids; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Nifedipine; Phenylephrine; Potassium; Prostate; Prostatic Hyperplasia; Rats; Rats, Wistar; Spleen; Stereoisomerism; Vas Deferens; Vasodilator Agents | 1999 |
Investigation of the subtypes of alpha1-adrenoceptor mediating contractions of rat vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Epididymis; Imidazoles; In Vitro Techniques; Indoles; Male; Methoxamine; Muscle Contraction; Nifedipine; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Vas Deferens | 1999 |
Contribution of sarcoplasmic reticulum calcium uptake and L-type calcium channels to altered vascular responsiveness in the aorta of renal hypertensive rats.
Topics: Animals; Aorta; Caffeine; Calcium; Calcium Channels, L-Type; Hypertension, Renal; In Vitro Techniques; Male; Nifedipine; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Thapsigargin; Vasoconstriction | 1999 |
Effects of different vasodilators on human internal mammary artery in vitro.
Topics: Ethanolamines; Female; Humans; In Vitro Techniques; Isoproterenol; Isosorbide Dinitrate; Male; Mammary Arteries; Middle Aged; Myocardial Ischemia; Nifedipine; Phenylephrine; Potassium Chloride; Propranolol; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Relaxation to flavones and flavonols in rat isolated thoracic aorta: mechanism of action and structure-activity relationships.
Topics: Animals; Aorta, Thoracic; Apigenin; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Flavonoids; Flavonols; In Vitro Techniques; Luteolin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Quercetin; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2000 |
Regulation of renal artery smooth muscle tone by alpha1-adrenoceptors: role of voltage-gated calcium channels and intracellular calcium stores.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Diltiazem; Dioxanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Ischemia; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phenoxybenzamine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Renal Artery; Renal Circulation; Swine; Thapsigargin; Verapamil | 2000 |
The involvement of intracellular Ca(2+) in 5-HT(1B/1D) receptor-mediated contraction of the rabbit isolated renal artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actin Cytoskeleton; Animals; Caffeine; Calcium; Calcium Channel Blockers; Capillary Permeability; Dose-Response Relationship, Drug; Female; Fluorescence; Fura-2; Imidazoles; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Renal Artery; Serotonin; Thapsigargin; Vasoconstrictor Agents | 2000 |
Role of Ca2+- and swelling-activated Cl- channels in alpha1-adrenoceptor-mediated tone in pressurized rabbit mesenteric arterioles.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adrenergic alpha-Agonists; Analysis of Variance; Animals; Arterioles; Calcium Channel Blockers; Calcium Channels; Chloride Channels; In Vitro Techniques; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Niflumic Acid; Phenylephrine; Potassium Channels; Pressure; Rabbits; Tetraethylammonium; Vasodilation | 2000 |
Mechanisms of vasoinhibitory effect of cardioprotective agent, CP-060S, in rat aorta.
Topics: Angiotensin II; Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Arginine Vasopressin; Calcium; Calcium Channel Blockers; Cytosol; Dinoprost; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Effects of econazole on receptor-operated and depolarization-induced contractions in rat isolated aorta.
Topics: Animals; Antifungal Agents; Aorta; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Drug Interactions; Econazole; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Neuromuscular Depolarizing Agents; Nifedipine; Nitroarginine; Phentolamine; Phenylephrine; Potassium Chloride; Rats; Receptors, Adrenergic, alpha-1 | 2000 |
Increased dilator response to heptanol and octanol in aorta from DOCA-salt-hypertensive rats.
Topics: Animals; Aorta; Desoxycorticosterone; Dose-Response Relationship, Drug; Heptanol; Hypertension; In Vitro Techniques; Male; Nifedipine; Octanols; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Endothelium-independent vasorelaxation by leonurine, a plant alkaloid purified from Chinese motherwort.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Carotid Arteries; Dogs; Drug Interactions; Endothelium, Vascular; Gallic Acid; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Plant Extracts; Plants, Medicinal; Portal Vein; Potassium Chloride; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Relaxing effects of Ligstrum purpurascens extract and purified acteoside in rat aortic rings.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelium; Glucosides; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitric Oxide; Papaverine; Phenols; Phenylephrine; Phorbol Esters; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Vasodilator Agents | 2001 |
Pharmacological evidence for capacitative Ca(2+) entry in cannulated and pressurized skeletal muscle arterioles.
Topics: Actins; Animals; Arterioles; Boron Compounds; Calcium; Calcium Channel Blockers; Cytoskeleton; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Manganese; Muscle, Skeletal; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Rats; Rats, Sprague-Dawley; Thapsigargin; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Kavain attenuates vascular contractility through inhibition of calcium channels.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Kava; Male; Molecular Structure; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Plant Extracts; Plant Roots; Pyrones; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstriction; Vasodilation | 2002 |
Phasic contractions of the rat portal vein depend on intracellular Ca2+ release stimulated by depolarization.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Chloride Channels; Cyclooxygenase Inhibitors; Electric Stimulation; Isotonic Solutions; Male; Nifedipine; Niflumic Acid; Phenylephrine; Phosphodiesterase Inhibitors; Portal Vein; Potassium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 2003 |
Investigation of postjunctional alpha1- and alpha2-adrenoceptor subtypes in vas deferens from wild-type and alpha(2A/D)-adrenoceptor knockout mice.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Cocaine; Electric Stimulation; Imidazoles; Indoles; Isoindoles; Isometric Contraction; Male; Mice; Mice, Knockout; Nifedipine; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Purinergic; Suramin; Thymine; Vas Deferens; Yohimbine | 2003 |
Evidence for the mechanisms underlying the effects of pimaradienoic acid isolated from the roots of Viguiera arenaria on rat aorta.
Topics: Animals; Aorta, Thoracic; Asteraceae; Brazil; Diterpenes; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethanol; Indomethacin; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nifedipine; Oxadiazoles; Phenylephrine; Plant Extracts; Plant Roots; Quinoxalines; Rats; Rats, Wistar; Tetraethylammonium; Vasoconstriction; Vasodilation | 2004 |
Effects of thiol chelation on alpha1-adrenoceptor-induced vasoconstriction in vivo.
Topics: Adrenergic alpha-Agonists; Animals; Dose-Response Relationship, Drug; Hydroxymercuribenzoates; Male; Nifedipine; Norepinephrine; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sulfhydryl Reagents; Vasoconstriction; Vasodilator Agents | 2005 |
Diverse effects of calcium channel blockers in the collar model.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Calcium Channel Blockers; Carotid Artery, Common; Endothelium, Vascular; Female; Histamine Agents; Male; Models, Animal; Models, Cardiovascular; Niacinamide; Nifedipine; Phenylephrine; Potassium Chloride; Rabbits; Serotonin; Serotonin Agents; Tunica Intima; Vasodilation; Vasodilator Agents | 2005 |
Effects of hypoxia on the vasodilator activity of nifedipine and evidence of secondary pharmacological properties.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Cocaine; Dose-Response Relationship, Drug; Hypoxia; In Vitro Techniques; Male; Nifedipine; Norepinephrine; Phenylephrine; Propranolol; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Thromboxane receptor stimulation suppresses guanylate cyclase-mediated relaxation of radial arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adrenergic alpha-Agonists; Calcium Channel Blockers; Colforsin; Coronary Artery Bypass; Epoprostenol; Guanylate Cyclase; Humans; Internal Mammary-Coronary Artery Anastomosis; Isometric Contraction; Mammary Arteries; Nifedipine; Nitric Oxide; Nitroglycerin; Norepinephrine; Organ Specificity; Phenylephrine; Potassium Chloride; Radial Artery; Receptors, Cytoplasmic and Nuclear; Receptors, Thromboxane; Soluble Guanylyl Cyclase; Thromboxane A2; Vascular Patency; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Investigation of the pronounced synergism between prostaglandin E2 and other constrictor agents on rat femoral artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Dinoprostone; Drug Interactions; Drug Synergism; Femoral Artery; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Nifedipine; Phenylephrine; Potassium; Prostaglandins F, Synthetic; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP3 Subtype; rho-Associated Kinases; Sensitivity and Specificity; Sulfonamides; Vasoconstrictor Agents | 2006 |
Calcium channel blocking activity of calycosin, a major active component of Astragali Radix, on rat aorta.
Topics: Animals; Aorta, Thoracic; Astragalus propinquus; Calcium; Calcium Channel Blockers; Calcium Chloride; Dose-Response Relationship, Drug; Endothelium, Vascular; Isoflavones; Male; Muscle Contraction; Nifedipine; Phenylephrine; Plant Roots; Plants, Medicinal; Potassium Chloride; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2006 |
Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Ductus Arteriosus; Enzyme Activation; Enzyme Induction; Feedback, Physiological; Female; Fetal Heart; Gestational Age; Humans; Hydrogen Peroxide; Hypoplastic Left Heart Syndrome; Infant, Newborn; Intracellular Signaling Peptides and Proteins; Male; Mitochondria, Heart; Nifedipine; Organ Culture Techniques; Oxidation-Reduction; Oxygen; Partial Pressure; Phenylephrine; Protein Serine-Threonine Kinases; Pyridines; Rabbits; Reactive Oxygen Species; rho-Associated Kinases; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Superoxides; Vasoconstriction | 2007 |
Inositol-1,4,5-trisphosphate-mediated spontaneous activity in mouse embryonic stem cell-derived cardiomyocytes.
Topics: Action Potentials; Aniline Compounds; Animals; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cell Differentiation; Cell Line; Embryonic Stem Cells; Endothelin-1; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Heart Rate; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; Microscopy, Confocal; Myocytes, Cardiac; Nifedipine; Phenylephrine; Pyrrolidinones; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Calcium Exchanger; Time Factors; Type C Phospholipases; Xanthenes | 2007 |
Role of K(+) channels in the regulation of electrical spontaneous activity of the mouse small intestine.
Topics: 4-Aminopyridine; Animals; Apamin; Charybdotoxin; Electrophysiology; Female; Ileum; Male; Mice; Mice, Inbred BALB C; Nifedipine; Peptides; Phenylephrine; Potassium Channels; Potassium Channels, Calcium-Activated; Tetrodotoxin | 2007 |
Effects of anethole and structural analogues on the contractility of rat isolated aorta: Involvement of voltage-dependent Ca2+-channels.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Aorta; Calcium; Calcium Channels; Cardiovascular Agents; Diltiazem; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavoring Agents; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; NG-Nitroarginine Methyl Ester; Nifedipine; Organ Culture Techniques; Oxidants; Phenylephrine; Rats; Rats, Wistar; Structure-Activity Relationship; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
Rho kinase is involved in Ca2+ entry of rat penile small arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Amides; Animals; Arteries; Bacterial Toxins; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Penis; Phenylephrine; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; rho-Associated Kinases; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Vasorelaxant effect of a self-etch adhesive system through calcium antagonistic action.
Topics: 4-Aminopyridine; Animals; Aorta, Thoracic; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Dentin-Bonding Agents; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Glyburide; Indomethacin; Male; Materials Testing; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
alpha(1)-adrenoceptor modulation of spontaneous electrical waveforms in the guinea-pig prostate.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Guinea Pigs; Histamine; Indoles; Male; Membrane Potentials; Microelectrodes; Nifedipine; Niflumic Acid; Phenylephrine; Prostate; Receptors, Adrenergic, alpha-1; Uncoupling Agents | 2009 |
Hypotensive and endothelium-independent vasorelaxant effects of methanolic extract from Curcuma longa L. in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Calcium; Calcium Channel Blockers; Curcuma; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethnopharmacology; In Vitro Techniques; Male; Mesenteric Arteries; Methanol; Nifedipine; Phenylephrine; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Solvents; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
Epinephrine, phenylephrine, and methoxamine induce infiltrative anesthesia via alpha1-adrenoceptors in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Anesthesia, Local; Anesthetics, Local; Animals; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Male; Methoxamine; Nifedipine; Nitroglycerin; Pain Measurement; Phentolamine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 2009 |
Marfan syndrome decreases Ca2+ wave frequency and vasoconstriction in murine mesenteric resistance arteries without changing underlying mechanisms.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cations, Divalent; Disease Models, Animal; In Vitro Techniques; Marfan Syndrome; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Sarcoplasmic Reticulum; Vasoconstriction | 2011 |
Addition of phenylephrine to high-dose insulin in dihydropyridine overdose does not improve outcome.
Topics: Animals; Calcium Channel Blockers; Drug Overdose; Hemodynamics; Insulin; Nifedipine; Phenylephrine; Shock, Cardiogenic; Swine; Vasoconstriction | 2010 |
First prize: Chitosan and the urothelial barrier: effects on ureteral intraluminal drug penetration and peristalsis.
Topics: Animals; Awards and Prizes; Chitosan; Nifedipine; Peristalsis; Permeability; Phenylephrine; Staining and Labeling; Sus scrofa; Ureter; Urothelium | 2011 |
Mineralocorticoids participate in the reduced vascular reactivity of pregnant rats.
Topics: Aldosterone; Animals; Aorta, Thoracic; Benzimidazoles; Calcium Channel Blockers; Canrenoic Acid; Cromakalim; Female; KATP Channels; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium Channels, Calcium-Activated; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Renin-Angiotensin System; Vasoconstrictor Agents; Vasodilator Agents | 2012 |
The effect of first-in-class small molecule RhoA inhibitor, HL07, on the phenylephrine-induced artery contraction.
Topics: Animals; Aorta, Thoracic; Cells, Cultured; Cinnamates; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Male; Myocytes, Smooth Muscle; Nifedipine; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; RNA, Messenger; Thapsigargin; Vasoconstriction; Vasoconstrictor Agents | 2012 |
The novel phenylpropiophenone derivates induced relaxation of isolated rat aorta.
Topics: Animals; Aorta; In Vitro Techniques; Lidocaine; Male; Nifedipine; Phenylephrine; Propafenone; Propiophenones; Rats; Rats, Wistar; Structure-Activity Relationship; Vasodilation | 2012 |
Cyclic AMP relaxation of rat aortic smooth muscle is mediated in part by decrease of depletion of intracellular Ca(2+) stores and inhibition of capacitative calcium entry.
Topics: Animals; Aorta, Thoracic; Calcium; Colforsin; Cyclic AMP; Imidazoles; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Phosphodiesterase 4 Inhibitors; Pyridines; Rats; Rats, Inbred WKY; Rolipram; Vasodilation; Vasodilator Agents; Verapamil | 2013 |
Nitric oxide and TNFα are critical regulators of reversible lymph node vascular remodeling and adaptive immune response.
Topics: Adaptive Immunity; Animals; Arterioles; Cell Degranulation; Chlorocebus aethiops; Female; Herpes Simplex; Lymph Nodes; Mast Cells; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase Type III; Phenylephrine; Tumor Necrosis Factor-alpha; Vasoconstriction; Vasodilator Agents; Vero Cells | 2013 |
Enhanced contractility in pregnancy is associated with augmented TRPC3, L-type, and T-type voltage-dependent calcium channel function in rat uterine radial artery.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Endothelium, Vascular; Female; Muscle Contraction; Muscle, Smooth, Vascular; Myography; Nifedipine; Phenylephrine; Pregnancy; Pyrazoles; Rats; Rats, Sprague-Dawley; TRPC Cation Channels; Uterine Artery; Vasoconstriction; Vasoconstrictor Agents | 2013 |
Calcium oscillations in human mesenteric vascular smooth muscle.
Topics: Adolescent; Adult; Aged; Aniline Compounds; Boron Compounds; Calcium Signaling; Cell Membrane; Female; Humans; Hypercholesterolemia; Hypertension; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Microscopy, Confocal; Microscopy, Electron; Middle Aged; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Sarcoplasmic Reticulum; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Xanthenes | 2014 |
Enhanced vasoconstriction to α1-adrenoceptor stimulation during cooling in mouse cutaneous plantar arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Arteries; Calcium Channel Blockers; Cold Temperature; Enzyme Inhibitors; In Vitro Techniques; Male; Mice; Nifedipine; Phenylephrine; Receptors, Adrenergic, alpha-1; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Skin; Thapsigargin; Vasoconstriction; Vasodilator Agents | 2014 |
Endothelium-Independent Vasorelaxant Effect of Ligusticum jeholense Root and Rhizoma on Rat Thoracic Aorta.
Topics: Animals; Aorta, Thoracic; Atropine; Calcium; Calcium Channels; Endothelium, Vascular; Extracellular Space; In Vitro Techniques; Indomethacin; Ligusticum; Male; Nifedipine; Phenylephrine; Plant Extracts; Plant Roots; Potassium Channels; Potassium Chloride; Rats; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2015 |
Endothelium-independent vasorelaxant activity of Trachyspermum ammi essential oil on rat aorta.
Topics: Animals; Aorta; Aorta, Thoracic; Apiaceae; Calcium; Calcium Channel Blockers; Cyclohexane Monoterpenes; Cymenes; Enzyme Inhibitors; Hypertension; Monoterpenes; NG-Nitroarginine Methyl Ester; Nifedipine; Oils, Volatile; Phenylephrine; Plant Oils; Rats; Rats, Wistar; Thymol; Vasodilation | 2017 |
Lipid emulsion alleviates the vasodilation and mean blood pressure decrease induced by a toxic dose of verapamil in isolated rat aortae and an in vivo rat model.
Topics: Animals; Aorta, Thoracic; Bepridil; Blood Pressure; Calcium Channel Blockers; Diltiazem; Emulsions; In Vitro Techniques; Male; Nifedipine; Phenylephrine; Phospholipids; Rats; Rats, Sprague-Dawley; Soybean Oil; Vasodilation; Vasodilator Agents; Verapamil | 2018 |
Differential contribution of calcium channels to α
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Body Temperature Regulation; Calcium; Calcium Channel Blockers; Calcium Channels; Cold Temperature; Iliac Artery; Large-Conductance Calcium-Activated Potassium Channels; Male; Models, Animal; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Phosphorylation; Protein Phosphatase 1; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; rho-Associated Kinases; Signal Transduction; Vasoconstriction | 2018 |
Mechanism of Membrane Depolarization Involved in α
Topics: Acetamides; Adrenergic alpha-1 Receptor Agonists; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Iliac Artery; Imidazoles; Isoquinolines; Male; Nifedipine; Phenylephrine; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tail; Tetrahydronaphthalenes; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2019 |
Itaconimides derivatives induce relaxation in mesenteric artery and negative inotropism by inhibition of CA
Topics: Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Imidazoles; Imides; Male; Mesenteric Arteries; Muscle Contraction; Nifedipine; Organ Culture Techniques; Phenylephrine; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2020 |