nifedipine has been researched along with phenobarbital in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (18.18) | 18.7374 |
| 1990's | 9 (20.45) | 18.2507 |
| 2000's | 18 (40.91) | 29.6817 |
| 2010's | 9 (20.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Sen, S; Sinha, N | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Tabrizchi, R; Triggle, CR | 1 |
| Koleva, M; Staneva-Stoytcheva, D | 1 |
| Czuczwar, SJ; Kleinrok, Z; Małek, U | 1 |
| Gross, RA; Macdonald, RL | 1 |
| Breimer, DD; Brugman, M; Schellens, JH; van der Wart, JH | 1 |
| Lyon, ME; Marks, GS; Owen, JA | 1 |
| Blouin, RA; Brouwer, KL; Chang, SL; Hamann, SR; Kaltenborn, KE; McAllister, RG; Tan, TG; Vore, M | 1 |
| Carpenter, CL; Cooper, EC; Greenberg, DA | 1 |
| Mendelson, WB | 1 |
| Bäärnhielm, C; Borg, KO; Skånberg, I | 1 |
| Koleva, MR; Stoychev, TS | 1 |
| Ben-Chitrit, S; Bernheim, J; Korzets, Z | 1 |
| Abrosimov, IIu; Karpova, MN; Kryzhanovskiĭ, GN | 1 |
| Iwasaki, K; Kato, R; Nozaki, K; Shiraga, T; Takanaka, A; Tamura, T; Yamazoe, Y | 1 |
| Ikeda, M; Kamata, R; Kasamo, K; Kojima, T; Nogami, Y; Okuhata, Y; Satoh, R; Takahashi, S | 1 |
| Satishchandra, P; Shankar, SK; Ullal, GR | 1 |
| Aso, Y; Kojima, S; Yoshioka, S | 3 |
| Bideci, A; Camurdan, MO; Cinaz, P; Demirel, F; Serdaroğlu, A | 1 |
| Aso, Y; Yoshioka, S | 1 |
| de Morais, SM; Fahmi, OA; Liras, JL; Maurer, TS; Mills, JB; Ripp, SL; Trevena, KA | 1 |
| Aso, Y; Hayashi, T; Kawanishi, T; Kitamura, S; Miyazaki, T; Muranushi, N; Takakura, A; Tanaka, K; Yoshioka, S | 1 |
| Akopova-Larbi, R; Ben Youssef, TI; Gargouri, A; Gouider, R; Gouider-Khouja, N; Kraoua, I | 1 |
| Bhugra, C; Caron, V; Pikal, MJ | 1 |
| Hayashi, M; Shou, M; Skiles, GL; Xu, Y; Zhou, Y | 1 |
1 review(s) available for nifedipine and phenobarbital
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
43 other study(ies) available for nifedipine and phenobarbital
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A comparison of the effects of acute versus chronic administration of phenoxybenzamine on pressor responses elicited by the selective alpha 1-adrenoceptor agonist cirazoline in the pithed rat preparation.
Topics: Adaptation, Physiological; Adrenergic alpha-Agonists; Anesthesia; Animals; Blood Pressure; Calcium; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Imidazoles; Male; Nifedipine; Phenobarbital; Phenoxybenzamine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Time Factors | 1992 |
Effect of nifedipine on the enzyme-inducing activity of phenobarbital and beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Hexobarbital; Liver; Male; Mixed Function Oxygenases; Nifedipine; Phenobarbital; Rats; Rats, Inbred Strains; Sleep | 1991 |
Influence of calcium channel inhibitors upon the anticonvulsant efficacy of common antiepileptics against pentylenetetrazol-induced convulsions in mice.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Ethosuximide; Male; Mice; Nifedipine; Pentylenetetrazole; Phenobarbital; Reference Values; Seizures; Valproic Acid; Verapamil | 1990 |
Barbiturates and nifedipine have different and selective effects on calcium currents of mouse DRG neurons in culture: a possible basis for differing clinical actions. The 1987 S. Weir Mitchell award.
Topics: Animals; Barbiturates; Calcium; Cells, Cultured; Ganglia, Spinal; Ion Channels; Mice; Neurons; Nifedipine; Pentobarbital; Phenobarbital | 1988 |
Influence of enzyme induction and inhibition on the oxidation of nifedipine, sparteine, mephenytoin and antipyrine in humans as assessed by a "cocktail" study design.
Topics: Adult; Antipyrine; Cimetidine; Enzyme Induction; Female; Humans; Hydantoins; Male; Mephenytoin; Metabolic Clearance Rate; Nifedipine; Oxidation-Reduction; Phenobarbital; Smoking; Sparteine | 1989 |
Xenobiotic mediated inhibition of hepatic uroporphyrinogen decarboxylase activity in 17-day-old chick embryo liver cells in culture.
Topics: Animals; Carboxy-Lyases; Cells, Cultured; Chick Embryo; Liver; Nifedipine; Oxygen; Phenobarbital; Polychlorinated Biphenyls; Porphyrins; Uroporphyrinogen Decarboxylase | 1988 |
Effects of phenobarbital and SKF-525A on in vitro hepatic metabolism of verapamil and nifedipine.
Topics: Animals; Cytochrome P-450 Enzyme System; In Vitro Techniques; Liver; Male; Metabolic Clearance Rate; Nifedipine; Phenobarbital; Proadifen; Rats; Rats, Inbred F344; Verapamil | 1985 |
Phenytoin interacts with calcium channels in brain membranes.
Topics: Animals; Brain; Calcium; Carbamazepine; Clonazepam; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1984 |
The benzodiazepine receptor and sleep.
Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Calcium; Carbolines; Diazepam; Flumazenil; Flurazepam; Humans; Motor Activity; Nifedipine; Phenobarbital; Pyrazoles; Rats; Receptors, GABA-A; Sleep; Synaptosomes | 1984 |
Cytochrome P-450-dependent oxidation of felodipine--a 1,4-dihydropyridine--to the corresponding pyridine.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 Enzyme System; Felodipine; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Nifedipine; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains | 1984 |
Effect of nifedipine, verapamil and diltiazem on the enzyme-inducing activity of phenobarbital and beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Diltiazem; Enzyme Induction; Male; Nifedipine; Oxidoreductases; Phenobarbital; Rats; Rats, Wistar; Verapamil | 1995 |
Bradycardia as a presenting feature of late postpartum eclampsia.
Topics: Adult; Bradycardia; Drug Therapy, Combination; Eclampsia; Female; Humans; Magnesium Sulfate; Nifedipine; Phenobarbital; Phenytoin; Pregnancy; Puerperal Disorders; Time Factors | 1994 |
[Anticonvulsant and neurotoxic effects of various combinations of phenobarbital, diazepam, sodium valproate, and 1,4-dihydropyridine ryodipine].
Topics: Animals; Anticonvulsants; Diazepam; Drug Combinations; Drug Synergism; Mice; Nervous System; Nifedipine; Phenobarbital; Valproic Acid | 1994 |
Isolation and characterization of four cytochrome P450 isozymes from untreated and phenobarbital-treated beagle dogs.
Topics: Amino Acid Sequence; Animals; Catalysis; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dogs; Electrophoresis, Polyacrylamide Gel; Hydroxylation; Immunoblotting; Isoenzymes; Male; Microsomes, Liver; Molecular Sequence Data; Molecular Weight; Nifedipine; Phenobarbital; Steroid 16-alpha-Hydroxylase; Testosterone | 1994 |
Chronological changes of MRI findings on striatal damage after acute cyanide intoxication: pathogenesis of the damage and its selectivity, and prevention for neurological sequelae: a case report.
Topics: Adult; Basal Ganglia; Brain Diseases; Carbamazepine; Corpus Striatum; Epilepsy, Temporal Lobe; Humans; Magnetic Resonance Imaging; Male; Nifedipine; Phenobarbital; Phenytoin; Potassium Cyanide; Suicide, Attempted | 1993 |
Effect of antiepileptic drugs and calcium channel blocker on hyperthermic seizures in rats: animal model for hot water epilepsy.
Topics: Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Disease Models, Animal; Electroencephalography; Epilepsy; Hippocampus; Hyperthermia, Induced; Injections, Intraperitoneal; Male; Nifedipine; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Seizures | 1996 |
Relationship between the crystallization rates of amorphous nifedipine, phenobarbital, and flopropione, and their molecular mobility as measured by their enthalpy relaxation and (1)H NMR relaxation times.
Topics: Crystallization; Kinetics; Magnetic Resonance Spectroscopy; Nifedipine; Phenobarbital; Propiophenones; Temperature; Thermodynamics | 2000 |
Explanation of the crystallization rate of amorphous nifedipine and phenobarbital from their molecular mobility as measured by (13)C nuclear magnetic resonance relaxation time and the relaxation time obtained from the heating rate dependence of the glass
Topics: Calcium Channel Blockers; Carbon Radioisotopes; Crystallization; Excitatory Amino Acid Antagonists; Magnetic Resonance Spectroscopy; Nifedipine; Phenobarbital; Temperature; Time Factors | 2001 |
Molecular mobility-based estimation of the crystallization rates of amorphous nifedipine and phenobarbital in poly(vinylpyrrolidone) solid dispersions.
Topics: Algorithms; Calorimetry, Differential Scanning; Crystallization; Kinetics; Nifedipine; Pharmaceutic Aids; Phenobarbital; Povidone; Suspensions; Thermodynamics | 2004 |
Persistent hyperinsulinemic hypoglycemia presenting with a rare complication: West syndrome.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Congenital Hyperinsulinism; Diazoxide; Electroencephalography; Female; Humans; Infant; Myoclonus; Nifedipine; Phenobarbital; Spasms, Infantile; Treatment Outcome | 2004 |
Molecular mobility of nifedipine-PVP and phenobarbital-PVP solid dispersions as measured by 13C-NMR spin-lattice relaxation time.
Topics: Carbon Isotopes; Crystallization; Magnetic Resonance Spectroscopy; Molecular Conformation; Nifedipine; Phenobarbital; Povidone; Temperature | 2006 |
Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction.
Topics: Algorithms; Carbamazepine; Cell Line; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Nifedipine; Phenobarbital; Phenytoin; Pioglitazone; Reproducibility of Results; Rifampin; Rosiglitazone; Sulfinpyrazone; Thiazolidinediones | 2006 |
Miscibility of nifedipine and hydrophilic polymers as measured by (1)H-NMR spin-lattice relaxation.
Topics: Calcium Channel Blockers; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Hypromellose Derivatives; Magnetic Resonance Spectroscopy; Methylcellulose; Nifedipine; Phenobarbital; Polymers; Povidone; Solubility | 2007 |
[Neurological complications of acute intermittent porphyria precipitated by porphyrinogenic drugs and efficiency of heme-arginate treatment].
Topics: Acute Disease; Adolescent; Arginine; Electromyography; Famotidine; Female; Heme; Heme Oxygenase (Decyclizing); Humans; Nifedipine; Peripheral Nervous System Diseases; Phenobarbital; Porphyrias; Porphyrinogens; Time Factors | 2009 |
Prediction of onset of crystallization in amorphous pharmaceutical systems: phenobarbital, nifedipine/PVP, and phenobarbital/PVP.
Topics: Crystallization; Drug Stability; Models, Chemical; Nifedipine; Phenobarbital; Povidone; Transition Temperature | 2010 |
Simulation of clinical drug-drug interactions from hepatocyte CYP3A4 induction data and its potential utility in trial designs.
Topics: Area Under Curve; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Midazolam; Nifedipine; Phenobarbital; Rifampin; Simvastatin; Substrate Specificity | 2011 |