nifedipine and perhexiline

nifedipine has been researched along with perhexiline in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199028 (75.68)18.7374
1990's0 (0.00)18.2507
2000's2 (5.41)29.6817
2010's7 (18.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Jia, L; Sun, H1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Sen, S; Sinha, N1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Short, D1
Castaño Bazo, L; de Castro del Pozo, S; Delcán, JL; Ledesma García, C; Martín Luengo, C; Pabón Osuna, P; Sala Sánchez-Castillo, A; Santos Rodríguez, I1
Sowton, E1
Breithaupt, H; Walter, P1
Affaki, GS; Bonan, R; Crittin, J; Mizgala, HF; Théroux, P; Waters, DD1
Adamska-Dyniewska, H; Dziekański, S1
Atkins, C; Bax, M; Psychoyos, S1
Martre, H; Singlas, E; Taburet, AM1
Briscoe, MG; Smith, HJ1
Barry, WH; Horowitz, JD; Smith, TW1
Opie, LH1
Fossati, C; Guistiniani, S1
Lewis, JG1
Donath, M; Ebner, F; Rämsch, KD1
Feely, J; Maclean, D1
Becker, HJ; Dowinsky, S; Hopf, R; Kaltenbach, M; Kober, G1
Forman, R; Kirk, ES1
Dipalma, JR1
Edvinsson, L; Johansson, BB; Larsson, B; MacKenzie, ET; Skärby, T; Young, AR1
Hochrein, H; Lehmann, HU1
Antman, EM; Braunwald, E; Muller, JE; Stone, PH1
Hayakawa, H; Kimura, E; Kishida, H; Kusama, Y; Otsu, F; Takayama, M1
Kimura, M; Ono, H1
Bergey, JL; McCallum, JD; Nocella, K1
Nayler, WG1
Flaim, SF; Zelis, R1
Aziza, JP; Blanchard, D; Guermonprez, JL; Lancelin, B; Maurice, P1

Reviews

9 review(s) available for nifedipine and perhexiline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Treatment of angina pectoris (III)].
    Die Medizinische Welt, 1979, Feb-16, Volume: 30, Issue:7

    Topics: Angina Pectoris; Angina Pectoris, Variant; Coronary Artery Bypass; Humans; Nifedipine; Perhexiline; Prenylamine; Vasodilator Agents; Verapamil

1979
[Clinical pharmacology of calcium inhibitors].
    Archives des maladies du coeur et des vaisseaux, 1985, Volume: 78 Spec No

    Topics: Age Factors; Animals; Bepridil; Biological Availability; Biotransformation; Calcium Channel Blockers; Diltiazem; Dogs; Half-Life; Humans; Intestinal Absorption; Kidney Failure, Chronic; Kinetics; Liver Diseases; Metabolic Clearance Rate; Nifedipine; Perhexiline; Protein Binding; Pyrrolidines; Rats; Tissue Distribution; Verapamil

1985
[Side-effects of calcium antagonists].
    La Clinica terapeutica, 1984, Jun-30, Volume: 109, Issue:6

    Topics: Calcium Channel Blockers; Cardiovascular Diseases; Drug Hypersensitivity; Drug Interactions; Fendiline; Gastrointestinal Diseases; Humans; Lidoflazine; Nervous System Diseases; Nifedipine; Perhexiline; Prenylamine; Verapamil

1984
Adverse reactions to calcium antagonists.
    Drugs, 1983, Volume: 25, Issue:2

    Topics: Calcium Channel Blockers; Diltiazem; Drug Interactions; Humans; Kinetics; Lidoflazine; Nifedipine; Perhexiline; Prenylamine; Risk; Verapamil

1983
Clinical differentiation of nifedipine and other calcium antagonists.
    Arquivos brasileiros de cardiologia, 1984, Volume: 43, Issue:1

    Topics: Biological Availability; Calcium Channel Blockers; Diltiazem; Drug Tolerance; Heart Diseases; Hemodynamics; Humans; Kinetics; Nifedipine; Perhexiline; Verapamil

1984
[Treatment of angina pectoris with calcium antagonists].
    Herz, 1982, Volume: 7, Issue:4

    Topics: Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Therapy, Combination; Exercise Test; Fendiline; Humans; Nicardipine; Nifedipine; Perhexiline; Prenylamine; Propafenone; Propiophenones; Verapamil

1982
[Indications for use of calcium antagonists].
    Medizinische Klinik, 1980, Apr-11, Volume: 75, Issue:8

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Cardiotonic Agents; Coronary Disease; Female; Fendiline; Humans; Hyperinsulinism; Hypertension; Nifedipine; Obstetric Labor, Premature; Paraganglioma; Perhexiline; Pregnancy; Prenylamine; Vasodilator Agents; Verapamil

1980
Calcium channel blocking agents in the treatment of cardiovascular disorders. Part II: Hemodynamic effects and clinical applications.
    Annals of internal medicine, 1980, Volume: 93, Issue:6

    Topics: Benzazepines; Calcium Channel Blockers; Cardiovascular Diseases; Coronary Circulation; Diltiazem; Hemodynamics; Humans; Myocardial Contraction; Nifedipine; Nitrogen; Perhexiline; Piperidines; Pyridines; Regional Blood Flow; Vasodilation; Verapamil

1980

Other Studies

28 other study(ies) available for nifedipine and perhexiline

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Angina.
    British medical journal, 1978, Sep-30, Volume: 2, Issue:6142

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Humans; Isosorbide Dinitrate; Nifedipine; Nitroglycerin; Perhexiline

1978
[Physiopathological and therapeutical considerations of Prinzmetal's angina. Apropos of 7 cases].
    Revista clinica espanola, 1979, Apr-30, Volume: 153, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Angina Pectoris, Variant; Coronary Vessels; Electrocardiography; Humans; Male; Middle Aged; Nifedipine; Perhexiline; Vasodilator Agents

1979
The treatment of angina pectoris.
    The Practitioner, 1979, Volume: 223, Issue:1336

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Coronary Angiography; Humans; Isosorbide Dinitrate; Middle Aged; Nifedipine; Nitroglycerin; Perhexiline; Physical Exertion; Prenylamine; Verapamil

1979
Provocative testing with ergonovine to evaluate the efficacy of treatment with calcium antagonists in variant angina.
    Circulation, 1979, Volume: 60, Issue:3

    Topics: Adult; Aged; Angina Pectoris; Angina Pectoris, Variant; Electrocardiography; Ergonovine; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Nifedipine; Perhexiline; Piperidines; Pyridines

1979
Drug treatment of chronic stable angina pectoris.
    British medical journal, 1978, Feb-25, Volume: 1, Issue:6111

    Topics: Angina Pectoris; Chronic Disease; Humans; Nifedipine; Nitrites; Perhexiline; Verapamil

1978
[Comparative studies on perhexiline, nifedipine and practolol in the light of spirometric and ergometric examinations].
    Kardiologia polska, 1978, Volume: 21, Issue:1

    Topics: Coronary Disease; Humans; Nifedipine; Perhexiline; Physical Exertion; Piperidines; Practolol; Pyridines; Spirometry

1978
Differences in Ca2+ entry blockers revealed by effects on adenosine- and adrenergic- receptors and cyclic AMP levels of [2-3H]adenine-prelabeled vesicles prepared from guinea pig brain.
    Biochemical pharmacology, 1986, May-15, Volume: 35, Issue:10

    Topics: Adenine; Adenosine; Animals; Arrhythmias, Cardiac; Brain Chemistry; Calcium Channel Blockers; Cell Membrane; Cyclic AMP; Epinephrine; Guinea Pigs; In Vitro Techniques; Nifedipine; Perhexiline; Prenylamine; Receptors, Adrenergic; Receptors, Cell Surface; Receptors, Purinergic; Stereoisomerism; Tritium; Verapamil

1986
The relative sensitization by acidosis of five calcium blockers in cat papillary muscles.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:7

    Topics: Acidosis; Animals; Calcium Channel Blockers; Cats; Diltiazem; In Vitro Techniques; Lidoflazine; Myocardial Contraction; Nifedipine; Papillary Muscles; Perhexiline; Verapamil

1985
Comparison of negative inotropic potency, reversibility, and effects on calcium influx of six calcium channel antagonists in cultured myocardial cells.
    British journal of pharmacology, 1985, Volume: 85, Issue:1

    Topics: Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Chick Embryo; Gallopamil; Half-Life; Lidoflazine; Myocardial Contraction; Myocardium; Nifedipine; Perhexiline; Time Factors; Verapamil

1985
Drugs and the heart. III. Calcium antagonists.
    Lancet (London, England), 1980, Apr-12, Volume: 1, Issue:8172

    Topics: Angina Pectoris; Aniline Compounds; Arrhythmias, Cardiac; Calcium; Cardiomegaly; Diuretics; Heart Diseases; Heart Failure; Humans; Hypertension; Indapamide; Nifedipine; Perhexiline; Piperidines; Pyridines; Verapamil

1980
Calcium antagonists, nitrates, and new antianginal drugs.
    British medical journal (Clinical research ed.), 1983, Apr-02, Volume: 286, Issue:6371

    Topics: Angina Pectoris; Calcium Channel Blockers; Humans; Hypertension; Isosorbide Dinitrate; Lidoflazine; Nifedipine; Nitrates; Nitroglycerin; Perhexiline; Prenylamine; Tachycardia; Verapamil

1983
Comparative effects of vasodilator drugs on large and small coronary resistance vessels in the dog.
    Cardiovascular research, 1980, Volume: 14, Issue:10

    Topics: Animals; Coronary Vessels; Dogs; Nifedipine; Nitroglycerin; Nitroprusside; Perhexiline; Vascular Resistance; Vasodilator Agents; Verapamil

1980
Calcium channel blockers.
    American family physician, 1983, Volume: 27, Issue:2

    Topics: Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem; Half-Life; Heart Diseases; Humans; Hypertension; Kinetics; Myocardial Infarction; Nifedipine; Perhexiline; Vasodilator Agents; Verapamil

1983
Calcium antagonists: effects on cerebral blood flow and blood-brain barrier permeability in the rat.
    British journal of pharmacology, 1983, Volume: 79, Issue:1

    Topics: Animals; Blood Pressure; Blood-Brain Barrier; Calcium Channel Blockers; Cerebrovascular Circulation; Ethanol; Male; Nicotinic Acids; Nifedipine; Nimodipine; Perhexiline; Rats; Rats, Inbred Strains; Xenon Radioisotopes

1983
Effects of calcium antagonists, especially nifedipine, on variant angina, resting angina, and unstable angina.
    Japanese heart journal, 1982, Volume: 23, Issue:6

    Topics: Aged; Angina Pectoris; Angina Pectoris, Variant; Calcium Channel Blockers; Coronary Vasospasm; Diltiazem; Female; Humans; Male; Middle Aged; Nifedipine; Perhexiline; Prenylamine; Pyridines; Rest; Verapamil

1982
Effect of Ca2+-antagonistic vasodilators, diltiazem, nifedipine, perhexiline and verapamil, on platelet aggregation in vitro.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:7

    Topics: Adenosine Diphosphate; Adolescent; Adult; Calcium; Collagen; Diltiazem; Epinephrine; Humans; In Vitro Techniques; Male; Nifedipine; Perhexiline; Platelet Aggregation; Vasodilator Agents; Verapamil

1981
Antiarrhythmic evaluation of verapamil, nifedipine, perhexiline and skf 525-A in four canine models of cardiac arrhythmias.
    European journal of pharmacology, 1981, Mar-26, Volume: 70, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Calcium; Dogs; Female; Heart Rate; Lidocaine; Male; Myocardial Contraction; Nifedipine; Perhexiline; Piperidines; Proadifen; Pyridines; Verapamil

1981
Calcium antagonists.
    European heart journal, 1980, Volume: 1, Issue:3

    Topics: Angina Pectoris; Calcium Channel Blockers; Cell Membrane; Diltiazem; Heart; Humans; Hypertension; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardial Infarction; Myocardium; Nifedipine; Perhexiline; Verapamil

1980
Clinical use of calcium entry blockers.
    Federation proceedings, 1981, Volume: 40, Issue:14

    Topics: Angina Pectoris; Calcium Channel Blockers; Cinnarizine; Coronary Circulation; Coronary Vasospasm; Diltiazem; Flunarizine; Heart Rate; Humans; Lidoflazine; Nifedipine; Perhexiline; Verapamil

1981
[Calcium inhibitors. Current indications in cardiology].
    La Revue du praticien, 1980, Feb-01, Volume: 30, Issue:7

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium; Cardiovascular Diseases; Diltiazem; Humans; Nifedipine; Perhexiline; Prenylamine; Verapamil

1980