nifedipine and pentoxifylline

nifedipine has been researched along with pentoxifylline in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.41)18.7374
1990's6 (22.22)18.2507
2000's12 (44.44)29.6817
2010's6 (22.22)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Haustein, UF1
Demusz, CD; Weselcouch, EO1
Friederichs, E; Rädisch, T; Winkler, H1
Beykirch, H; Herrmann, W; Reuter, W; Voigt, H1
Calleja, F; Casares, J; Chacón-Quevedo, A; Concha, M; Eguaras, MG; Garcia, MA; Muñoz, I; Roman, M1
Evans, WK; Logan, D; Stewart, DJ1
Akopov, SE; Gabrielian, ES1
Oonishi, T; Sakashita, K; Uyesaka, N1
Bulaeva, SV; Chuchkanov, FA; Maimistova, AA; Muravyov, AV; Yakusevich, VV; Zaitsev, LG1
Buell, C; Lamp, K; Tobinick, E1
Ertem, K1
Horvath, B; Kesmarky, G; Toth, K; Vekasi, J1
Araújo, AC; Jorge, VC; Noronha, C; Panarra, A; Riso, N; Vaz Riscado, M1
Acar, M; Dogan, B; Senel, S; Zorlu, P1
Kirchhof, MG; Mahmood, F; Pratt, M1

Reviews

3 review(s) available for nifedipine and pentoxifylline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Current status and trends in treatment of scleroderma].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1992, Volume: 43, Issue:7

    Topics: Captopril; Combined Modality Therapy; Dextrans; Epoprostenol; Humans; Immunosuppressive Agents; Nifedipine; Pentoxifylline; Scleroderma, Systemic

1992
Pharmacologic Treatment of Idiopathic Chilblains (Pernio): A Systematic Review.
    Journal of cutaneous medicine and surgery, 2021, Volume: 25, Issue:5

    Topics: Chilblains; Humans; Nifedipine; Pentoxifylline; Vasodilator Agents

2021

Trials

2 trial(s) available for nifedipine and pentoxifylline

ArticleYear
Comparative evaluation of pentoxifylline, buflomedil, and nifedipine in the treatment of intermittent claudication of the lower limbs.
    Angiology, 1994, Volume: 45, Issue:7

    Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Exercise Test; Humans; Intermittent Claudication; Male; Middle Aged; Nifedipine; Pentoxifylline; Prospective Studies; Pyrrolidines; Vasodilator Agents; Walking

1994
The relationship between the degradation of prostacyclin in blood and antiplatelet drug effects in patients with atherosclerosis.
    Journal of clinical pharmacology, 1993, Volume: 33, Issue:11

    Topics: Arteriosclerosis; Dipyridamole; Double-Blind Method; Epoprostenol; Humans; Kinetics; Middle Aged; Nifedipine; Pentoxifylline; Platelet Aggregation; Platelet Aggregation Inhibitors

1993

Other Studies

22 other study(ies) available for nifedipine and pentoxifylline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogPoct: a tool for lipophilicity determination in drug discovery.
    Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Drug effects on function in the ferret ischemic hindlimb.
    Journal of pharmacological methods, 1990, Volume: 23, Issue:4

    Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Ferrets; Hindlimb; Ischemia; Isometric Contraction; Male; Muscle Contraction; Nifedipine; Pentoxifylline; Regional Blood Flow

1990
Calcium content of the erythrocytes: a sensitive and easy handling method for measuring free calcium ions, and modulation of the Ca2+ ion concentration by the calcium antagonists nifedipine and pentoxifylline.
    Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:5

    Topics: Adenosine Triphosphate; Calcimycin; Calcium; Erythrocytes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Ionophores; Nifedipine; Pentoxifylline; Temperature; Theobromine

1989
[Lipid metabolism and peripheral hemodynamics in arteriosclerosis obliterans treated with nifedipine--a comparison with pentoxifylline].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1989, Feb-01, Volume: 44, Issue:3

    Topics: Arteriosclerosis Obliterans; Hemodynamics; Humans; Ischemia; Leg; Lipids; Male; Middle Aged; Nifedipine; Pentoxifylline; Theobromine

1989
Addition of pentoxifylline plus nifedipine to chemotherapy in patients with cisplatin-resistant cancers of the lung and other sites.
    American journal of clinical oncology, 1994, Volume: 17, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Drug Evaluation; Drug Resistance; Female; Humans; Hypotension; Lung Neoplasms; Male; Neutropenia; Nifedipine; Ovarian Neoplasms; Pentoxifylline

1994
Regulation of red blood cell filterability by Ca2+ influx and cAMP-mediated signaling pathways.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Adult; Alprostadil; Calcium; Calcium Channel Blockers; Cyclic AMP; Dinoprostone; Epinephrine; Erythrocyte Deformability; Erythrocytes; Felodipine; Filtration; Humans; In Vitro Techniques; Kinetics; Male; Nifedipine; Pentoxifylline; Signal Transduction; Stress, Mechanical

1997
Hemorheological efficiency of drugs, targeting on intracellular phosphodiesterase activity: in vitro study.
    Clinical hemorheology and microcirculation, 2007, Volume: 36, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids

2007
Resolution of chronic pain and fingertip ulceration due to hand-arm vibration syndrome following combination pharmacotherapy.
    Archives of dermatology, 2007, Volume: 143, Issue:10

    Topics: Chronic Disease; Drug Therapy, Combination; Hand-Arm Vibration Syndrome; Humans; Male; Middle Aged; Nifedipine; Pain; Pentoxifylline; Raynaud Disease; Skin Ulcer; Vasodilator Agents

2007
Prolonged transient hand ischaemia secondary to a penicillin skin test.
    The Journal of hand surgery, European volume, 2007, Volume: 32, Issue:6

    Topics: Aspirin; Calcium Channel Blockers; Cyanosis; Drug Hypersensitivity; Drug Therapy, Combination; Fibrinolytic Agents; Fingers; Follow-Up Studies; Hand; Humans; Intradermal Tests; Ischemia; Male; Middle Aged; Nadroparin; Nifedipine; Penicillins; Pentoxifylline; Vasodilator Agents

2007
In vitro antioxidant properties of pentoxifylline and vinpocetine in a rheological model.
    Clinical hemorheology and microcirculation, 2008, Volume: 40, Issue:2

    Topics: Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Free Radical Scavengers; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids

2008
Buerger's disease (Thromboangiitis obliterans): a diagnostic challenge.
    BMJ case reports, 2011, Sep-13, Volume: 2011

    Topics: Adult; Angiography; Aspirin; Atorvastatin; Calcium Channel Blockers; Drug Therapy, Combination; Heparin, Low-Molecular-Weight; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iloprost; Male; Nifedipine; Pentoxifylline; Platelet Aggregation Inhibitors; Pyrroles; Smoking Cessation; Thromboangiitis Obliterans

2011
Successfully treated fingertip necrosis in an infant with primary Raynaud phenomenon.
    Indian journal of pediatrics, 2014, Volume: 81, Issue:12

    Topics: Anticoagulants; Drug Therapy, Combination; Enoxaparin; Fingers; Humans; Infant; Male; Necrosis; Nifedipine; Pentoxifylline; Raynaud Disease; Vasodilator Agents

2014