nifedipine has been researched along with nitrendipine in 537 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 410 (76.35) | 18.7374 |
| 1990's | 73 (13.59) | 18.2507 |
| 2000's | 31 (5.77) | 29.6817 |
| 2010's | 21 (3.91) | 24.3611 |
| 2020's | 2 (0.37) | 2.80 |
| Authors | Studies |
|---|---|
| Baldwin, JJ; Claremon, DA; Faison, EP; Kaczorowski, GJ; Lumma, PK; McClure, DE; Rosenthal, SA; Smith, GM; Trumble, MJ; Winquist, RJ | 1 |
| Aisaka, K; Cho, H; Hamaguchi, M; Hayashimatsu, M; Hidaka, T; Mizuno, A; Ohnaka, Y; Shima, K; Takeuchi, Y; Ueda, M | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Cillero, FJ; Fau de Casa-Juana, M; Ortega, MP; Priego, JG; Sunkel, CE | 1 |
| Böcker, RH; Guengerich, FP | 1 |
| Janis, RA; Triggle, DJ | 1 |
| Jacobson, KA; Jiang, JL; Melman, N; Olah, ME; Stiles, GL; van Rhee, AM | 1 |
| Goldmann, S; Hofmann, HJ; Klossek, P; Scholz, GH; Thormann, M; Uhlig, M; Vieweg, S | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Beaumont, K; Smith, DA; van De Waterbeemd, H; Walker, DK | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Horinouchi, M; Komada, F; Nishiguchi, K; Ohmoto, N; Ohnishi, N; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y; Yokoyama, T | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Keserü, GM | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Einzinger, U; Hoda, JC; Huber, IG; Koschak, A; Obermair, GJ; Sartori, SB; Sinnegger-Brauns, MJ; Striessnig, J; Wild, C | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D | 1 |
| Cao, S; Chang, CC; Dunne, SF; Kai, L; Kang, S; Luan, CH; Pandey, P; Silverman, RB; Surmeier, DJ; Tian, X | 1 |
| Reimão, JQ; Scotti, MT; Tempone, AG | 1 |
| Sen, S; Sinha, N | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Sun, H | 1 |
| Caron, G; Ermondi, G; Galietta, L; Medana, C; Pedemonte, N; Visentin, S | 1 |
| Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Burburan, PJ; Matubia, VN; Parkin, DW; Ramcharan, SS; Rosario, I; Shea, TA; Stockman, BJ | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF | 1 |
| Chen, J; Han, C; Huang, MX; Li, Z; Liu, RD; Luo, HB; Tian, YJ; Wu, Y; Xie, X; Yang, YY; Yuan, Y | 1 |
| Haruno, A; Kanda, A; Miyake, H; Nagasaka, M | 1 |
| Keck, M | 1 |
| Arita, M; Chien, Y; Frohlich, ED; Sasaki, O | 1 |
| Nayler, WG | 2 |
| Kennedy, RH; Ruch, S; Seifen, E | 1 |
| Metelitsa, VI; Ostrovskaia, TP | 1 |
| Mason, RP; Moisey, DM; Shajenko, L | 1 |
| Borges, ET; Christeler, P; Guillaume-Gentil, M; Hollenstein, U; Mannhart, M; Waeber, B | 1 |
| Antkiewicz-Michaluk, L; Michaluk, J; Romańska, I; Vetulani, J | 2 |
| Frank, GB | 1 |
| Glossmann, H; Graziadei, I; Moshammer, T; Reider, N; Zech, C; Zernig, G | 1 |
| Akimoto, T; Ariyoshi, S; Fujisue, T; Ichida, S; Wada, T | 1 |
| Gambini, F; Gaviraghi, G; Micheli, D; Quartaroli, M; Tarter, G; Trist, DG | 1 |
| Attali, JR; Perret, G; Uzzan, B; Valensi, P | 1 |
| Aihara, H; Kaneko, K; Tsuchida, K | 1 |
| Boonen, GJ; de Koster, BM; Elferink, JG | 1 |
| Abbate, R; Boddi, M; Coppo, M; Gensini, GF; Neri Serneri, GG; Prisco, D; Rostagno, C | 1 |
| Ahr, G; Baunack, AR; Konrad-Dalhoff, I; Kraft, H; Kuhlmann, J; Rämsch, KD; Schmitz, H; Weihrauch, TR | 1 |
| Block, LH; Emmons, LR; Erne, P; Matthys, H; Perruchoud, A; Roth, M | 1 |
| Beressem, P; Englert, R; Kramar, M; Stafunsky, M; von Manteuffel, E | 1 |
| Brown, CB; el Nahas, AM; Wight, JP | 1 |
| de Faria, MG; Leite, CM; Mill, JG; Pires, JG | 1 |
| Attali, JR; Perret, G; Uzzan, B; Valensi, P; Vassy, R | 1 |
| Masumoto, N; Miyake, A; Tanizawa, O; Tasaka, K | 1 |
| Böhm, M; Erdmann, E; Schwinger, RH | 1 |
| Burdet, R; Criscione, L; Nellis, P; Riniker, B; Thomann, H | 1 |
| Logan, BK; Patrick, KS | 1 |
| Abe, K; Hashimoto, J; Imai, K; Imai, Y; Minami, N; Munakata, M; Nihei, M; Sakuma, H; Sasaki, S; Sekino, H | 1 |
| Danielson, M; Danielsson, BR; Dencker, L; Regård, CG; Reiland, S; Rundqvist, E | 1 |
| Angeid-Backman, E; Favus, MJ | 1 |
| Baik, YH; Dube, GP; Schwartz, A; Vaghy, PL | 1 |
| Brown, AM; Yatani, A | 1 |
| Hosey, MM; McMahon, KK; Ptasienski, J | 1 |
| Langer, SZ; Schoemaker, H | 1 |
| Kojima, I; Kojima, K; Rasmussen, H | 3 |
| Lafaille, F; Nair, NP; Quirion, R | 1 |
| Bean, BP | 2 |
| Carpenter, CL; Cooper, EC; Greenberg, DA | 4 |
| Lee, HR; Roeske, WR; Watson, M; Yamamura, HI | 1 |
| Brown, AM; Dumont, L; Grupp, G; Grupp, IL; Hamilton, S; Schwartz, A; Vaghy, PL; Williams, JS; Yatani, A | 1 |
| Batra, S | 1 |
| Gopalakrishnan, V; Park, LE; Triggle, CR | 1 |
| Dillon, JS; Elz, JS; McKelvie, M; Nayler, WG | 1 |
| Lazdunski, M; Renaud, JF; Schmid, A | 1 |
| Forder, J; Rasmussen, H; Scriabine, A | 1 |
| Carpenter, CL; Greenberg, DA; Messing, RO | 2 |
| Bolli, P; Bühler, FR; Erne, P; Hulthén, UL; Ji, BH; Kiowski, W; Müller, FB | 1 |
| Pedrinelli, R; Tarazi, RC | 4 |
| Criscione, L; Meier, M; Rogg, H; Truog, A | 1 |
| Battaini, F; Govoni, S; Rius, RA; Trabucchi, M | 2 |
| Colucci, WS; Powers, RE | 1 |
| Golichowski, AM; Tzeng, DY | 1 |
| Aguilera, G; Catt, KJ | 1 |
| Schiebinger, RJ | 1 |
| Litzinger, MJ; Nelson, PG; Pun, RY | 1 |
| Carboni, E; Costa, E; Wojcik, WJ | 1 |
| Borosky, SA; Cooper, CW; Farrell, PE; Steinsland, OS | 1 |
| Holck, M; Osterrieder, W | 1 |
| Bryant, SH; Schwartz, A; Walsh, KB | 1 |
| Harris, KM; Kongsamut, S; Miller, RJ | 1 |
| Benavides, J; Bertrand, P; Burgevin, MC; Doble, A; Ferris, O; Gueremy, C; Le Fur, G; Menager, J; Uzan, A; Vaucher, N | 1 |
| Delpont, E; Desnuelle, C; Lazdunski, M; Renaud, JF; Serratrice, G | 1 |
| Cooper, MS; Schliwa, M | 1 |
| Kongsamut, S; Miller, RJ | 1 |
| Haase, H; Vetter, R; Will, H; Will-Shahab, L | 1 |
| Adkins, E; Emmert, S; Ludden, CT; Ribeiro, LG; Seymour, AA; Sweet, CS | 1 |
| Finkel, MS; Keiser, HR; Marks, ES; Patterson, RE; Speir, EH; Steadman, K | 1 |
| Murawsky, MM; O'Leary, ME; Suszkiw, JB; Wang, T | 1 |
| Borsotto, M; Hosey, MM; Lazdunski, M | 1 |
| Hock, CE; Lefer, AM; Whitney, CC | 1 |
| Lazdunski, M; Qar, J; Schmid, A; Schweitz, H | 1 |
| Bhalla, RC; Butters, CA; Sharma, RV | 1 |
| Garcia, ML; Kaczorowski, GJ; King, VF; Reuben, JP; Siegl, PK | 1 |
| Catt, KJ; Chang, JP; Graeter, J; McCoy, EE; Tasaka, K | 1 |
| Ando, J; Ishii, K; Kano, T | 1 |
| Collins, SM | 1 |
| Bean, BP; Hermsmeyer, K; Puga, A; Sturek, M | 1 |
| Brenneman, DE; Lazdunski, M; Litzinger, MJ; Lombet, A | 1 |
| Dalaker, K; Prydz, H | 1 |
| Andresen, MC; Kunze, DL; Torres, LA | 1 |
| Berg, C; DiFrancesco, GF; Gittos, M; Mir, AK; Petty, MA; Spedding, M | 1 |
| Bechem, M; Metzger, G; Schramm, M; Thomas, G | 1 |
| DeRoth, L; Godfraind, T; Wibo, M | 1 |
| Gallant, S; Gengo, P; Hawthorn, M; Moran, JF; Skattebøl, A; Triggle, DJ | 1 |
| Bolger, GT; Weissman, BA | 1 |
| Carboni, E; Wojcik, WJ | 1 |
| Asano, M; Inagaki, O; Kubo, K; Takenaka, T; Terai, M | 1 |
| Bagwell, EE; Hungerford, RT; Lindenmayer, GE; Serafino, R | 1 |
| Darszon, A; de De la Torre, L; García-Soto, J; López-Colomé, AM; Mourelle, M; Ramírez, E; Vargas, I | 1 |
| Massieu, L; Tapia, R | 1 |
| Gandhi, VC; Jones, DJ | 1 |
| Burges, RA; Carter, AJ; Gardiner, DG | 1 |
| Cortese, C; Ferrara, LA; Gnasso, A; Mancini, M; Marotta, T; Pasanisi, F | 1 |
| Grosser, KD; Späh, F | 1 |
| Kashiwabara, T; Nakayama, K; Tanaka, Y; Yamada, S | 1 |
| Donowitz, M; Homaidan, FR; Sharp, GW; Weiland, GA | 1 |
| Bose, D; Bouchard, RA; Chau, T; Hryshko, LV; Saha, JK | 1 |
| Chartrand, C; Dumont, L; Kangha, M; Lord, C | 1 |
| Batra, SC; Popper, LD | 1 |
| Hyman, PE; Jing, J; Martin, MG; Snape, WJ; Tomomasa, T | 1 |
| Burges, RA; Carter, AJ; Dodd, MG; Gardiner, DG; Sutton, MR | 1 |
| Belin, C; Carriot, T; Doble, A; Dubroeucq, MC; Guérémy, C; Le Fur, G; Mestre, M; Renault, C; Uzan, A | 1 |
| Marban, E; Wier, WG | 1 |
| Chung, M; Cohen, CJ; Thomas, G | 1 |
| Ferry, DR; Glossmann, H; Goll, A; Linn, T | 1 |
| Goldin, SM; Turner, TJ | 1 |
| Freedman, SB; Kongsamut, S; Miller, RJ | 1 |
| Bolli, P; Brouwer, RM; Bühler, FR; Conen, D; Erné, P; Kiowski, W | 1 |
| Bender, AS; Hertz, L | 1 |
| De Souza, EB; Kuhar, MJ; Titeler, M | 1 |
| Culvenor, AJ; Dawson, RM; Freeman, SE; Keeghan, AM | 1 |
| Bolger, GT; Skolnick, P; Weissman, BA | 1 |
| Locher, R; Neyses, L; Stimpel, M; Streuli, R; Vetter, W | 1 |
| Battaini, F; Govoni, S; Lucchi, L; Pasinetti, G; Trabucchi, M | 1 |
| Battaini, F; Bianchi, A; Govoni, S; Rius, RA; Trabucchi, M | 1 |
| Dretchen, KL; Henderson, TR; Raines, A | 1 |
| Jarvi, EJ; Meyer, MC; Patrick, KS; Straughn, AB | 1 |
| Seuter, F | 1 |
| Heagerty, AM; Swales, JD | 1 |
| Abelardo, NS; Mendoza, VL; Mitchell, MJ; Ramos, EF; Sulit, YQ | 1 |
| Hardman, JM; Lee, HC; Lum, BK | 1 |
| Dahlheim, H; Garthoff, B; Gomba, S; Jacob, I; Kazda, S; Reiter, W; Rosenthal, J; Rothemund, J; Thurnreiter, M; von Lutterotti, N | 1 |
| Badger, EW; Haleen, SJ; Pugsley, TA; Shih, YH; Steffen, RP; Taylor, MD; Weishaar, RE | 1 |
| Finkel, MS; Keiser, HR; Patterson, RE; Roberts, WC; Smith, TD | 1 |
| Knaus, EE; Li-Kwong-Ken, MC; Soboleski, DA; Triggle, CR; Wolowyk, MW; Wynn, H | 1 |
| Demuth, SM; Pong, SF; White, RL | 1 |
| Boyd, R; Giacomini, JC; Giacomini, KM; Nelson, WL; Wong, FM; Zobrist, RH | 1 |
| Doyle, AE | 2 |
| Amery, A; Ditu, M; Fagard, R; Lepira, B; Lijnen, P; M'Buyamba-Kabangu, JR; Tshiani, KA | 1 |
| Mahmoudian, M; Richards, WG | 1 |
| Kannan, MS; Seip, AE | 1 |
| Debbas, NM; Kovacs, IB; Sowemimo-Coker, SO; Turner, P | 1 |
| de Simone, G; Fasano, ML; Ferrara, LA; Gagliardi, R; Soro, S | 1 |
| Hanada, S; Tanaka, C | 1 |
| Balwierczak, JL; Schwartz, A | 1 |
| Bolger, GT; Rafferty, MF; Skolnick, P | 2 |
| Broughton Pipkin, F; Chinnery, E | 1 |
| Grover, AK; Oakes, PJ | 1 |
| Aimi, M; Bianco, C; Conti, G; Corbacelli, C; Cosmi, F; Mollaioli, M; Ricca, M | 1 |
| Frohlich, ED | 1 |
| Bauer, JH; Reams, G; Sunderrajan, S | 1 |
| Bolli, P; Bühler, FR; Erne, P; Fadayomi, MO; Hulthén, UL; Kiowski, W; Müller, FB | 1 |
| Montague, W; Morgan, NG; Rumford, GM; Short, CD | 1 |
| Moser, K; Rubin, LJ | 1 |
| Bravo, EL; Fouad, FM; Pedrinelli, R; Tarazi, RC; Textor, SC | 1 |
| Kamei, C; Kurokawa, K; Tasaka, K | 1 |
| Aihara, H; Fujita, A; Muramatsu, M; Tanaka, M | 1 |
| Amoroso, A; Bossini, A; Di Veroli, C | 1 |
| Huszar, G; Sakamoto, H | 2 |
| Paladini, G | 1 |
| Buescher, P; de la Monte, SM; Farrukh, I; Gottlieb, J; Gurtner, G; Hutchins, GM; Kennedy, TP; Lodato, R; Michael, JR; Rock, PC | 1 |
| Satoh, K; Taira, N; Wada, Y | 1 |
| Benetos, A; Bouthier, JD; Hugues, CM; Levenson, JA; Safar, ME; Simon, AC | 1 |
| Johnson, BF; Marwaha, R; Romero, L | 1 |
| Balwierczak, JL; Grupp, G; Grupp, IL; Schwartz, A | 1 |
| Ashraf, M; Grupp, I; Park, WH; Schwartz, A | 1 |
| Maillet, M; Nahas, G; Trouve, R | 1 |
| Lee, HC; Lum, BK | 1 |
| Cruz, LJ; Olivera, BM | 1 |
| Brenneman, DE; Foster, G; Litzinger, MJ | 1 |
| Brown, NL; Sirugue, O; Worcel, M | 1 |
| Ando, J; Ishii, K; Kano, T; Yoshida, H | 1 |
| Fishbaugh, J; Freeman, L; Powers, V; Van Sant, R; Yen, A | 1 |
| Horiuchi, K; Horiuchi, KY; Jurman, ME; Ohnishi, ST; Sadanaga, KK | 1 |
| Dubyak, GR; Reynolds, EE | 1 |
| Govoni, S; Rius, RA; Trabucchi, M | 1 |
| De Cesare, N; Galli, C; Guazzi, MD; Salvioni, A; Tamborini, G | 1 |
| Nishino, N; Noguchi-Kuno, SA; Sugiyama, T; Tanaka, C | 1 |
| Kessel, D | 1 |
| Mimran, A; Ribstein, J | 1 |
| Dolin, SJ; Little, HJ | 1 |
| Wang, ZY; Yuan, XZ; Zhang, HX | 1 |
| Debbas, NM; Jackson, SH; Turner, P | 1 |
| Blanke, R; Schnitker, J; Stahmann, J; Varchmin, G | 1 |
| Carpenter, R; Cohen, ML; Mason, N; Schenck, K; Wittenauer, L | 1 |
| Bolger, GT; Rafferty, MF; Rice, KC; Skolnick, P; Weissman, BA | 1 |
| Milovanovic, SR; Prostran, M; Prostran, MS; Varagic, VM; Vasiljevic, Z | 1 |
| Farmer, BB; Green, FJ; Jose, MJ; Watanabe, AM; Wiseman, GL | 1 |
| Gould, RJ; Murphy, KM; Snyder, SH | 5 |
| Lee, HR; Roeske, WR; Schoemaker, H; Yamamura, HI | 2 |
| Bailey, IA; Harris, DR; von Tscharner, V | 1 |
| Godfraind, T; Wibo, M | 1 |
| Bolger, GT; Ruzycky, A; Triggle, DJ; Yousif, FB | 1 |
| Bühler, FR; Erne, P; Resink, TJ | 1 |
| Goldman, ME; Pisano, JJ | 1 |
| Dhalla, NS; Elimban, V; Takeo, S | 1 |
| Fawzi, AB; McNeill, JH | 2 |
| Donoso, P; Hidalgo, C; Jaimovich, E; Liberona, JL | 1 |
| Chernow, B; McMillan, M; Roth, BL | 1 |
| Drewe, JA; Schilling, WP | 1 |
| Navarro, J | 1 |
| Dudeck, P; Reynolds, IJ; Snyder, SH; Wagner, JA; Weisfeldt, ML; Weisman, HF | 1 |
| Kemsies, C; Küttner, I; Vetter, R; Will, H; Will-Shahab, L | 1 |
| Barrett, JE; Bolger, GT; Lueddens, H; Paul, SM; Skolnick, P; Weissman, BA; Witkin, J | 1 |
| Campbell, KP; Kahl, SD; Sharp, A; Strom, M | 1 |
| Bolger, GT; Skolnick, P | 1 |
| Schwartzkroin, PA; Taube, JS | 1 |
| Arima, H; Fujita, S; Furuya, T; Inagaki, O; Isomura, Y; Kojima, T; Okada, M; Takenaka, T; Tamazawa, K; Terai, M | 1 |
| Barbieri, L; Camerini, F; Mestroni, L | 1 |
| Bratell, S; Folmerz, P; Hansson, R; Jonsson, O; Lundstam, S; Pettersson, S; Rippe, B; Scherstén, T | 1 |
| Bowling, N; Conery, BG; Hayes, JS; Kauffman, RF | 1 |
| Baky, S; Nademanee, K; Singh, BN | 1 |
| Brenneman, DE; Litzinger, MJ | 2 |
| Brandt, NR; Caswell, AH; Kawamoto, RM | 1 |
| Schwartz, J; Velly, J | 1 |
| Blasini, R; Brügmann, U; Reiniger, G; Rudolph, W | 1 |
| Greenberg, A; Puschett, JB; Wallia, R | 1 |
| Andrejauskas, E; Hertel, R; Marmé, D | 1 |
| Beck, O; Ryman, T | 1 |
| Franz, IW; Wiewel, D | 2 |
| Ene, MD; Roberts, CJ; Waddell, G; Williamson, PJ | 1 |
| de Divitiis, O; Di Somma, S; Fazio, S; Galderisi, M; Iacono, C; Petitto, M | 1 |
| Bouthier, JD; De Luca, N; Safar, ME; Simon, AC | 1 |
| Bruno, P; Bylund, DB; Harris, RA; Jones, SB | 1 |
| Langewitz, W; Neus, J; Rüddel, H; Schmieder, R; von Eiff, AW; Wagner, O | 2 |
| McCabe, EJ; Meeran, MK; Smith, VE; White, WB | 1 |
| Lee, SM; Michael, UF | 1 |
| Oswald, RE; Weiland, GA | 1 |
| Jaros, JA; Lee, HR; Roeske, WR; Ursillo, R; Wiech, NL; Yamamura, HI | 1 |
| Edmonds, D; Groth, H; Mosca, R; Stimpel, M; Vetter, W | 1 |
| Edmonds, D; Förster, E; Siegenthaler, W; Vetter, W; Wehling, M | 1 |
| Brown, AM; Hamilton, SL; Hawkes, MJ; Redding, K; Yatani, A | 1 |
| de Divitiis, O; Di Somma, S; Fazio, S; Galderisi, M; Petitto, M; Santomauro, M; Villari, B | 1 |
| Aronoff, GR; Sloan, RS | 1 |
| Chiang, DH; Wei, JW | 1 |
| Demus, JR; Nahas, G; Trouvé, R; von Sitbon, M | 1 |
| Fasano, ML; Ferrara, LA; Soro, S | 1 |
| Epstein, M; Hamburger, R; Horton, C; Loutzenhiser, R | 1 |
| Lim, SL; May, PB; Sutter, MC | 1 |
| Ishii, A; Nakamizo, N; Nishida, K; Oka, T | 2 |
| Karasawa, A; Kubo, K; Nakamizo, N; Oka, T | 1 |
| Ikeda, J; Karasawa, A; Kubo, K; Nakamizo, N; Oka, T; Yamada, K | 1 |
| Geoffroy, M; Mogilnicka, E; Nielsen, M; Rafaelsen, OJ | 1 |
| Schoenberger, JA | 1 |
| Katz, AM; Leach, NM | 1 |
| Graefe, KH; Rämsch, KD; Schmitz, H; Wingender, W; Ziegler, R | 1 |
| O'Regan, MH; Phillis, JW; Walter, GA | 1 |
| Angignard, D; Cahn, J; Greiner, PO | 1 |
| Endou, K; Sato, T; Yamamoto, H | 1 |
| Rao, MR | 1 |
| Mooy, JM; Rahn, KH; van Bortel, LM | 1 |
| Nicita-Mauro, V | 1 |
| Brown, T; Fogel, R; Gaginella, T; Marshall, D; Michelson, G; Senler, T | 1 |
| Camilión de Hurtado, MC; Gende, OA | 1 |
| Bengtsson, B; Khan, AR; Weiber, R | 1 |
| Joubert, WS; Kociszewska, VJ; Meyer, AC; Meyer, BJ; Nieuwenhuis, JJ | 1 |
| Giacomini, JC; Giacomini, KM; Nelson, WL; Zobrist, RH | 1 |
| Maclean, D; Mitchell, ET; Readman, AS | 1 |
| Enomoto, H; Hayashi, S; Kano, S; Kimura, K; Kimura, Y; Matsuzaki, T; Miura, A; Taniguchi, N; Ukai, Y | 1 |
| Graefe, KH; Rämsch, KD; Scherling, D; Sommer, J; Ziegler, R | 1 |
| Fischli, W; Hengartner, U; Holck, M | 1 |
| Bellemann, P | 1 |
| Cohn, JN; Levine, TB; Olivari, MT | 1 |
| Bouthier, J; Levenson, J; Maarek, BC; Safar, ME; Simon, AC | 1 |
| Rutsch, W; Schmutzler, H | 1 |
| Frohlich, ED; Kobrin, I; Pegram, BL; Sesoko, S | 2 |
| Huelsemann, JL; McKenzie, DE; Sterzel, RB; Wilcox, CS | 1 |
| Hall, CE; Hungerford, S | 3 |
| Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C | 1 |
| Detry, JM; Lavenne, F; Melin, JA; Nannan, ME; Vanbutsele, RJ | 1 |
| Jain, AK; Maronde, R; McMahon, FG; Mroczek, W; Ryan, JR; Vlachakis, N | 1 |
| Höffler, D; Stoepel, K | 1 |
| Corsing, C; Deck, K; Ingram, C; Stoepel, K; Vanov, SK | 1 |
| Block, LH; Bolli, P; Bühler, FR; Erne, P; Kiowski, W; Müller, FB | 1 |
| Drayer, JI; Weber, MA | 1 |
| Burris, JF; Lunn, J; Moser, M; Nash, DT; Simon, G; Vlachakis, ND; Winer, N | 1 |
| Lasaridis, A; Settas, L; Tourkantonis, A | 1 |
| Baglivo, HP; Castro, JM; Esper, RC; Esper, RJ; Menna, J; Rohwedder, RW | 1 |
| Distler, A; Fritschka, E; Gotzen, R; Philipp, T; Thiede, HM | 1 |
| Glasser, SP; Leibowitz, DA; McMahon, SG; Ram, CV; Schoenberger, JA; Vanov, SK | 1 |
| Deedwania, PC; Fagan, TC; Mehta, JL; Sternleib, C; Vlachakis, N | 1 |
| Bühler, FR; Distler, A; Laragh, JH; Tourkantonis, D; Valdes, G; Weber, MA | 1 |
| Hermsmeyer, K; Kuthe, C | 1 |
| Anderson, CL; Janis, RA; Kojima, K; Lee, S; Michal, U; Rasmussen, H; Scriabine, A | 1 |
| Anderson, CL; Johnson, CE; Scriabine, A; Steinsland, OS | 1 |
| Garthoff, B; Kazda, S; Luckhaus, G | 1 |
| Burkholder, DE; Kann, J; Krol, GJ; Levitt, MJ; Raemsch, KD | 1 |
| Aronoff, GR | 1 |
| Burkholder, DE; Krol, GJ; Lasseter, KC; Murdoch, AA; Shamblen, EC; Taylor, RJ; Vanov, SK | 1 |
| Heidemann, H; Hutt, HJ; Janisch, HD; Kirch, W; Ohnhaus, EE; Rämsch, K | 1 |
| Trost, BN; Weidmann, P | 1 |
| Bolli, P; Bühler, FR; Erne, P; Hulthén, UL; Ji, BH; Kiowski, W; Ritz, R | 1 |
| Groth, H; Locher, R; Neyses, L; Stimpel, M; Vetter, W | 1 |
| Kass, RS; Sanguinetti, MC | 1 |
| Fosset, M; Lazdunski, M; Meaux, JP; Renaud, JF; Schmid, A | 1 |
| Lee, HR; Roeske, WR; Yamamura, HI | 2 |
| Kirley, TL; Schwartz, A | 1 |
| Jones, H; Khandwala, A; Van Inwegen, RG; Weinryb, I | 1 |
| Fosset, M; Galizzi, JP; Lazdunski, M | 1 |
| Brady, J; Buja, LM; Bush, L; Gandler, T; Haghani, Z; McBride, W; Mukherjee, A; Wheeler-Clark, E; Willerson, JT | 1 |
| Gengo, PJ; Janis, RA; Triggle, DJ; Yousif, F | 1 |
| Küffer, B; Locher, R; Neyses, L; Stimpel, M; Vetter, W | 1 |
| Garcia, ML; Kaczorowski, GJ; Reuben, JP; Trumble, MJ | 1 |
| Gould, RJ; Murphy, KM; Reynolds, IJ; Snyder, SH | 2 |
| Johnson, CE; Scriabine, A; Steinsland, OS | 1 |
| Lues, I; Schümann, HJ | 2 |
| Brooks, HL; Gross, GJ; Warltier, DC; Zyvoloski, MG | 2 |
| Bühler, FR | 1 |
| Aboul-Khair, M; Fouad, FM; Tarazi, RC | 1 |
| Andrén, L; Hansson, L; Orö, L; Ryman, T | 1 |
| Albus, U; Ferry, DR; Glossmann, H; Habermann, E | 1 |
| Janis, RA; Rampe, D; Sarmiento, JG; Triggle, DJ | 1 |
| Freedman, SB; Miller, DM; Miller, RJ; Tindall, DR | 1 |
| Freedman, SB; Miller, RJ | 2 |
| Grupp, G; Grupp, IL; Schwartz, A; Vaghy, PL | 1 |
| Balwierczak, JL; Grupp, G; Grupp, IL; Schwartz, A; Vaghy, PL; Williams, JS | 1 |
| Adelstein, RS; Movsesian, MA | 1 |
| Janis, RA; Rampe, D; Triggle, DJ | 1 |
| Bolger, GT; Janis, RA; Maurer, SC; Sarmiento, JG; Triggle, DJ | 2 |
| Grupp, G; Grupp, IL; Schwartz, A; Vaghy, PL; Williams, JS | 1 |
| Tremble, P; Williams, LT | 1 |
| Toll, L | 1 |
| DePover, A; Dubé, GP; Grupp, G; Grupp, IL; Lee, SW; Matlib, MA; Schwartz, A | 1 |
| Boles, RG; Roeske, WR; Schoemaker, H; Yamamura, HI | 3 |
| Hughes, RJ; Insel, PA; Motulsky, HJ; Snavely, MD | 1 |
| Delpont, E; Fosset, M; Jaimovich, E; Lazdunski, M | 2 |
| Beatty, DA; Colker, JE; Fairhurst, AS; Thayer, SA | 1 |
| Borsotto, M; Ellory, JC; Fosset, M; Lazdunski, M; Norman, RI | 1 |
| Lee, KS; Tsien, RW | 1 |
| Colvin, RA; Janis, RA; Katz, AM; Sarmiento, JG; Triggle, DJ | 1 |
| Catterall, WA; Curtis, BM | 1 |
| Bolger, G; Fraser, CM; Jung, CY; Schaber, JS; Triggle, DJ; Venter, JC | 1 |
| Ferry, DR; Glossmann, H; Goll, A | 1 |
| Barry, WH; Lachance, D; Loh, E; Marsh, JD; Smith, TW | 1 |
| Kazazoglou, T; Lazdunski, M; Renaud, JF; Schmid, A | 2 |
| Itoh, T; Kanmura, Y; Kuriyama, H; Makita, Y; Suzuki, H | 1 |
| Kazazoglou, T; Lazdunski, M; Renaud, JF; Romey, G; Schmid, A | 1 |
| Bewtra, A; Cheng, JB; Townley, RG | 1 |
| Daniel, EE; Grover, AK; Kwan, CY; Luchowski, E; Triggle, DJ | 1 |
| Bühler, FR; Bürgisser, E; Dubach, B; Erne, P; Kühnis, H; Meier, M; Rogg, H | 1 |
| Marangos, PJ; Patel, J; Sperelakis, N | 1 |
| Barhanin, J; Giglio, JR; Ildefonse, M; Lazdunski, M; Rougier, O; Sampaio, SV | 1 |
| Cantor, EH; Kenessey, A; Semenuk, G; Spector, S | 1 |
| Janis, RA; Pan, M | 1 |
| Chatelain, P; Demol, D; Roba, J | 1 |
| Campbell, KP; Denney, GH; Lipshutz, GM | 1 |
| Gengo, PJ; Janis, RA; Luchowski, E; Rampe, DE; Rutledge, A; Triggle, AM; Triggle, DJ | 1 |
| Rudolph, SA; Thorgeirsson, G | 1 |
| Hakim, G; Hrelia, S; Ronca, G; Ronca-Testoni, S; Rossi, CA | 1 |
| Horne, P; Triggle, DJ; Venter, JC | 1 |
| Simon, G; Snyder, DK | 1 |
| Altura, BM; Altura, BT | 1 |
| Burka, JF; Saad, MH | 1 |
| Capobianchi, MR; Dianzani, F; Facchini, J | 1 |
| Janis, RA; Luchowski, EM; Maurer, SC; Sarmiento, JG; Triggle, DJ; Yousif, F | 1 |
| Pelto, DJ; Rapoport, SI; Suarez-Isla, BA; Thompson, JM | 1 |
| Garthoff, B; Knorr, A | 1 |
| Aguila, E; Baz, R; Lopez, LM; Mehta, JL | 1 |
| Aguilera, G; Catt, KJ; Finkel, MS; Keiser, HR | 1 |
| Kaiser, J; Lindner, E; Ruppert, D | 1 |
| Janis, RA; Katz, AM; Sarmiento, JG; Triggle, DJ | 1 |
| Ambrose, JM; Dachiw, J; Michalak, RJ; Silver, PJ | 1 |
| Gopalakrishnan, V; Triggle, CR | 1 |
| Luu, MD; Martin, JV; Mendelson, WB; Paul, SM; Skolnic, P; Wagner, R | 1 |
| Gould, RJ; Reynolds, IJ; Snyder, SH | 1 |
| Nickerson, PA | 1 |
| Govoni, S; Lucchi, L; Rius, RA; Trabucchi, M | 1 |
| Epstein, M; Loutzenhiser, R | 1 |
| Moscona-Amir, E; Sokolovsky, M | 1 |
| Adelstein, RS; Movsesian, MA; Swain, AL | 1 |
| Gould, RJ; Largent, BL; Murphy, KM; Snyder, SH | 1 |
| Kessel, D; Wilberding, C | 1 |
| Pang, DC; Sperelakis, N | 2 |
| Jespersen, LT; Mikkelsen, E; Pedersen, OL | 1 |
| Bailey, IA; von Tscharner, V | 1 |
| Barr, EM; Daniell, LC; Leslie, SW | 1 |
| Erman, RD; Roeske, WR; Yamamura, HI | 1 |
| Henry, PD; Wahl, AM | 1 |
| Hesse, RJ; Messerli, FH; Monica, ML | 1 |
| Karl, W; Meyer, H; Scherling, D | 1 |
| Hock, CE; Lefer, AM; Su, JY | 1 |
| Miller, WC; Moore, JB | 1 |
| Frohlich, ED; Pegram, BL; Sesoko, S | 1 |
| Abi-Samra, F; Bravo, EL; Fouad, FM; Pedrinelli, R; Tarazi, RC; Textor, SC | 1 |
| Garthoff, B; Kazda, S; Knorr, A | 1 |
| Dunn, FG; Frohlich, ED; Messerli, FH; Oigman, W; Reisin, E; Ventura, HO | 1 |
| Bolger, GT; Gengo, P; Janis, RA; Klockowski, R; Luchowski, E; Siegel, H; Triggle, AM; Triggle, DJ | 1 |
| Ando, J; Ishii, K; Kano, T; Kurobe, Y | 1 |
| Jones, LR; Williams, LT | 1 |
| Quirion, R | 1 |
| Janis, RA; Krol, GJ; Noe, AJ; Pan, M | 1 |
| Murphy, KM; Snyder, SH | 1 |
| Ehlert, FJ; Itoga, E; Roeske, WR; Yamamura, HI | 2 |
| Bolger, GT; Gengo, PJ; Janis, RA; Luchowski, EM; Siegel, H; Triggle, DJ | 1 |
| Pert, CB; Quirion, R | 1 |
| Garthoff, B; Kazda, S; Knorr, A; Thomas, G | 1 |
| Marangos, PJ; Martino, AM; Miller, C; Patel, J | 1 |
| Agrawal, DK; Bolger, GT; Daniel, EE; Kwan, CY; Luchowski, EM; Triggle, CR; Triggle, DJ | 1 |
| Heise, A; Kazda, S; Stoepel, K | 1 |
| Knorr, A; Stoepel, K | 1 |
| Bellemann, P; Ferry, D; Glossman, H; Lübbecke, F | 1 |
| Bellemann, P; Ferry, D; Glossmann, H; Lübbecke, F | 1 |
| Chapunoff, D; Herman, CA; Romero, MA; Schulmeister, K; Skarda, S; Torres, OA | 1 |
| Brochu, M; Roy, B; Sicotte, B; St-Louis, J | 1 |
| Filloux, FM; Fitts, RC; Skeen, GA; White, HS | 1 |
| Floersheim, GL; Racine, C | 1 |
| Bonnaure-Mallet, M; Godeau, GJ; Tricot-Doleux, S | 1 |
| McCarron, RM; Nikodijevic, B; Nikodijevic-Kedeva, D; Spatz, M; Stanimirovic, DB | 1 |
| Chen, SC; Li, MR; Ma, G | 1 |
| Courseau, C; Garay, R; Giraud, F; Hannaert, P; Pallotta, M; Rota, R | 1 |
| Grantyn, R; Taschenberger, H | 1 |
| Czirfuzs, A; Fleckenstein-Grün, G; Frey, M; Matyas, S; Thimm, F | 1 |
| Buttrum, SM; Nash, GB; Perry, I | 1 |
| Herzig, S; Ruhnke, L; Wulf, H | 1 |
| Hauner, H; Meissner, C | 1 |
| Jacobs, U; Klehr, HU; Klein, B | 1 |
| Blanke, P; Reimnitz, P; Rohr, G | 1 |
| Chaylakhyan, LM; Grishchenko, VM; Zherelova, OM | 1 |
| Buxton, BF; Casley, D; Dauer, R; Gallicchio, M; Johnston, CI; Liu, JJ; Wojta, J | 1 |
| Arnold, JM; Bailey, DG; Spence, JD | 1 |
| Antkiewicz-Michaluk, L; Michaluk, J; Vetulani, J | 1 |
| Kojima, I; Mine, T; Sekine, N; Shibata, H; Totsuka, Y; Yasuda, H | 1 |
| Bachetti, T; Carboni, L; Ferri, S; Ratti, E; Spampinato, S; Van Amsterdam, FT | 1 |
| Floersheim, GL | 1 |
| Breimer, DD; Cohen, AF; Soons, PA | 1 |
| Breimer, DD; Cohen, AF; Mulders, TM; Schoemaker, HC; Soons, PA; Uchida, E | 1 |
| Ader, JL; Durand, D; Lloveras, JJ; Rostaing, L; Suc, JM; Tack, I; Tran-Van, T | 1 |
| Dhein, S; Klaus, W; Salameh, A; Simsek, S; Zhao, Y | 1 |
| Antkiewicz-Michaluk, L; Karolewicz, B; Michaluk, J; Vetulani, J | 2 |
| Okopién, B; Trzeciak, HI | 1 |
| Kikuchi, K; Sugawara, H; Tobise, K | 1 |
| Brauns, T; Glossmann, H; Haugland, RP; Kimball, SD; Prinz, H; Striessnig, J | 1 |
| Araki, H; Higuchi, S; Noguchi, K; Takahashi, K | 1 |
| Aşçi, R; Aybek, Z; Büyükalpelli, R; Sarikaya, S; Yildiz, S; Yilmaz, AF | 1 |
| Koizumi, S; Moriyama, Y; Ogura, A; Yamada, H; Yamaguchi, A | 1 |
| Argenziano, L; De Luca, N; Iovino, G; Izzo, R; Morisco, C; Parrella, L; Trimarco, B | 1 |
| Mironov, SL; Richter, DW | 1 |
| Ban, Y; Makita, T | 1 |
| Rosato Siri, MD; Uchitel, OD | 1 |
| Iuvone, PM; Uchida, K | 1 |
| Jaroszkiewicz, E; Marciniec, B; Ogrodowczyk, M; Patterson, LH; Taiwo, FA | 1 |
| Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S | 1 |
| Brochu, M; Picard, S; Simaan, M; St-Louis, J | 1 |
| Hohenegger, M; Kress, HG; Weigl, LG | 1 |
| Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA | 1 |
| Trimarco, B | 1 |
| Holzgreve, H | 1 |
| Cathala, L; Chesnoy-Marchais, D | 1 |
| Stiefelhagen, P | 1 |
| Budzko, D; Miki, T; Niki, I; Niwa, T; Senda, T; Yu, W | 1 |
| Loarca, F; Martínez-Cadena, G; Ruiz-Herrera, J; Salcedo-Hernández, R | 1 |
| Camargo, C; Núñez-Vergara, LJ; Ortiz, ME; Squella, JA | 1 |
| Basile, J | 1 |
| Correia-de-Sá, P; Costa, J; Lobo, MG | 1 |
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| Li, J; Li, QX; Liu, LL; Shao, L; Xia, L | 1 |
| Aires, V; Ducret, T; Guibert, C; Marthan, R; Rodat-Despoix, L; Rousseau, E; Savineau, JP | 1 |
| Ao, Y; Li, J; Li, QX; Song, RJ; Tie, CR; Xie, XF | 1 |
| Rey, O; Rozengurt, E; Sternini, C; Young, SH | 1 |
| Krzemiński, TF; Mitręga, KA; Porc, M; Varghese, B | 1 |
| Beydemir, S; Söyüt, H; Türkeş, C | 1 |
| Ishigai, M; Kato, M; Mitsui, T; Miyake, T; Nagao, S; Nemoto, T; Ogawa, K; Yamada, H | 1 |
| Chudoba, D; Drużbicki, K; Jarek, M; Jenczyk, J; Kiwilsza, A; Mielcarek, J; Pajzderska, A; Wąsicki, J | 1 |
16 review(s) available for nifedipine and nitrendipine
| Article | Year |
|---|---|
New developments in Ca2+ channel antagonists.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Electrophysiology; Heart; Humans; Ion Channels; Muscle Relaxation; Muscle, Smooth; Potassium; Sodium; Structure-Activity Relationship; Substrate Specificity | 1983 |
Property-based design: optimization of drug absorption and pharmacokinetics.
Topics: Animals; Biological Transport; Blood Proteins; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane; Drug Design; Eye; Humans; Intestinal Absorption; Models, Biological; Models, Molecular; Nasal Mucosa; Pharmaceutical Preparations; Pharmacokinetics; Prodrugs; Skin Absorption | 2001 |
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels | 2010 |
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells | 2022 |
Comparison of calcium antagonists with other antihypertensive agents.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Nitrendipine; Verapamil | 1985 |
Effects of calcium entry blockers on renin-angiotensin-aldosterone system, renal function and hemodynamics, salt and water excretion and body fluid composition.
Topics: Animals; Blood Pressure; Body Fluids; Calcium Channel Blockers; Diltiazem; Diuresis; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Nifedipine; Nitrendipine; Renal Circulation; Renin-Angiotensin System; Verapamil; Water-Electrolyte Balance | 1985 |
[Calcium antagonists in congestive heart failure].
Topics: Calcium Channel Blockers; Cardiomyopathy, Dilated; Diltiazem; Felodipine; Heart Failure; Hemodynamics; Humans; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Verapamil | 1988 |
Second-generation calcium antagonists: search for greater selectivity and versatility.
Topics: Animals; Bepridil; Calcium Channel Blockers; Cinnarizine; Electrophysiology; Flunarizine; Heart; Humans; Lidoflazine; Muscle, Smooth, Vascular; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyrrolidines; Structure-Activity Relationship | 1985 |
Calcium antagonists: use in hypertension evaluation of calcium antagonists in combination with diuretics.
Topics: Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Nitrendipine | 1988 |
Differential effects of 1,4-dihydropyridine calcium channel blockers: therapeutic implications.
Topics: Angina Pectoris; Calcium; Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Hemodynamics; Humans; Hypertension; Nifedipine; Nitrendipine | 1987 |
Effects of nitrendipine and other calcium antagonists on glucose metabolism in man.
Topics: Blood Glucose; Calcium Channel Blockers; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Glycated Hemoglobin; Homeostasis; Humans; Insulin; Nifedipine; Nitrendipine | 1984 |
Are dihydropyridine binding sites voltage sensitive calcium channels?
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; Ion Channels; Muscle, Smooth; Muscles; Myocardium; Neurons; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyridines | 1984 |
The heterogeneity of the slow channel blockers (calcium antagonists).
Topics: Binding Sites; Calcium Channel Blockers; Cell Membrane; Chemical Phenomena; Chemistry; Humans; Nifedipine; Nitrendipine; Papaverine; Verapamil | 1983 |
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cerebrovascular Circulation; Cerebrovascular Disorders; Coronary Disease; Diabetes Mellitus; Dihydropyridines; Female; Humans; Hypertension; Ketamine; Magnesium; Magnesium Deficiency; Microcirculation; Muscle, Smooth, Vascular; Muscles; Nifedipine; Nisoldipine; Nitrendipine; Nutritional Requirements; Pentobarbital; Pre-Eclampsia; Pregnancy; Pyridines; Rats; Vasoconstrictor Agents; Vasodilator Agents; Venules | 1984 |
Grapefruit juice and drugs. How significant is the interaction?
Topics: Beverages; Biological Availability; Citrus; Dihydropyridines; Drug Interactions; Felodipine; Flavanones; Flavonoids; Half-Life; Humans; Nifedipine; Nitrendipine | 1994 |
The role of existing and newer calcium channel blockers in the treatment of hypertension.
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Nitrendipine; Treatment Outcome; Verapamil | 2004 |
47 trial(s) available for nifedipine and nitrendipine
| Article | Year |
|---|---|
Comparison of the efficacy of nilvadipine and nitrendipine on circadian blood pressure.
Topics: Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Placebos | 1992 |
[The efficacy of nitrendipine in patients with stable arterial hypertension. The data from a cooperative study in the USSR. The Working Group for the Cooperative Study of Nitrendipine].
Topics: Adult; Chi-Square Distribution; Drug Tolerance; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Nifedipine; Nitrendipine; Propranolol; USSR | 1992 |
Amlodipine compared to nitrendipine in hypertensive patients: the effects on toleration in relationship to the onset of action.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Nifedipine; Nitrendipine | 1992 |
Effects of nifedipine and nitrendipine on insulin secretion in obese patients.
Topics: Adult; Analysis of Variance; Blood Glucose; C-Peptide; Double-Blind Method; Female; Humans; Hypertension; Insulin; Insulin Secretion; Male; Middle Aged; Nifedipine; Nitrendipine; Obesity; Time Factors | 1991 |
Effect of the calcium antagonists nifedipine, nitrendipine, nimodipine and nisoldipine on oesophageal motility in man.
Topics: Administration, Oral; Adult; Calcium Channel Blockers; Double-Blind Method; Esophagogastric Junction; Esophagus; Humans; Male; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Peristalsis; Pressure | 1991 |
Amlodipine compared to nitrendipine for the treatment of mild-to-moderate hypertension.
Topics: Amlodipine; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Vasodilation | 1991 |
Effect of nifedipine and nitrendipine on insulin release in non-diabetic obese patients: a double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Glucose; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Nifedipine; Nitrendipine; Obesity | 1991 |
Acute and chronic effects of dihydropyridines on triglycerides in humans.
Topics: Adult; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Random Allocation; Triglycerides | 1988 |
Treatment of hypertensive urgencies and emergencies with nitrendipine, nifedipine, and clonidine: effect on blood pressure and heart rate.
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Clonidine; Drug Therapy, Combination; Emergencies; Female; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Nifedipine; Nitrendipine | 1988 |
Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Proline; Renin; Renin-Angiotensin System; Spironolactone; Verapamil | 1985 |
A double-blind randomized cross-over study of the efficacy and tolerability of nifedipine and nitrendipine in the treatment of mild to moderate hypertension.
Topics: Adult; Aged; Blood Chemical Analysis; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Patient Compliance; Random Allocation | 1989 |
A comparison of felodipine and nifedipine as monotherapies for the treatment of mild to moderate hypertension.
Topics: Adult; Blood Pressure; Body Weight; Clinical Trials as Topic; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine | 1989 |
Relative potency of a beta-blocking and a calcium entry blocking agent as antihypertensive drugs in black patients.
Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Black or African American; Body Weight; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Pulse; Random Allocation; Renin; Time Factors | 1986 |
Ex vivo effects of nifedipine, nisoldipine and nitrendipine on filterability of red blood cells from healthy volunteers.
Topics: Adult; Double-Blind Method; Erythrocyte Deformability; Female; Humans; Male; Nifedipine; Nisoldipine; Nitrendipine; Random Allocation | 1985 |
Antihypertensive and cardiovascular effects of nitrendipine: a controlled study vs. placebo.
Topics: Administration, Oral; Adult; Blood Pressure; Double-Blind Method; Drug Evaluation; Echocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Physical Exertion | 1985 |
Age, race, blood pressure and renin: predictors for antihypertensive treatment with calcium antagonists.
Topics: Adolescent; Adult; Age Factors; Aged; Black People; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Regression Analysis; Renin; Verapamil | 1985 |
Hemodynamic and metabolic effects of the calcium channel blocking agent nitrendipine.
Topics: Administration, Oral; Adult; Aged; Blood Glucose; Blood Pressure; Cholesterol; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Insulin; Male; Middle Aged; Nifedipine; Nitrendipine; Physical Exertion; Posture; Propranolol; Radioimmunoassay; Random Allocation; Renin; Vascular Resistance | 1986 |
Nitrendipine vs. long-acting nifedipine in mild, moderate and severe hypertension.
Topics: Adult; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Nifedipine; Nitrendipine | 1986 |
A comparison of the haemodynamic effects of nifedipine, nisoldipine and nitrendipine in man.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Hemodynamics; Humans; Male; Myocardial Contraction; Nifedipine; Nisoldipine; Nitrendipine; Pulse; Random Allocation; Stroke Volume | 1986 |
[Antihypertensive and anti-ischemic effect of nitrendipine. Double-blind, randomized, crossover and placebo controlled acute study].
Topics: Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Electrocardiography; Heart Rate; Humans; Hypertension; Nifedipine; Nitrendipine | 1985 |
[Antihypertensive effect of nitrendipine, nifedipine and acebutolol and their combination on resting and exercise blood pressure in hypertensive patients].
Topics: Acebutolol; Adult; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine | 1985 |
The natriuresis following oral administration of the calcium antagonists--nifedipine and nitrendipine.
Topics: Administration, Oral; Adolescent; Adult; Calcium Channel Blockers; Creatinine; Dose-Response Relationship, Drug; Humans; Male; Natriuresis; Nifedipine; Nitrendipine; Potassium | 1985 |
Muzolimine and nitrendipine in the treatment of arterial hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Electrolytes; Exercise Test; Female; Humans; Hypertension; Male; Middle Aged; Muzolimine; Nifedipine; Nitrendipine; Pyrazoles | 1985 |
[Verapamil and nitrendipine in beta blocker-resistant hypertensive patients].
Topics: Atenolol; Calcium Channel Blockers; Drug Resistance; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Verapamil | 1985 |
Nitrendipine and atenolol: comparison and combination in the treatment of arterial hypertension.
Topics: Adult; Atenolol; Blood Pressure; Body Weight; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hypertension; Male; Nifedipine; Nitrendipine; Pulse; Random Allocation | 1985 |
Calcium antagonists: use in hypertension evaluation of calcium antagonists in combination with diuretics.
Topics: Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Nitrendipine | 1988 |
Plasma concentration-response relationships for some cardiovascular effects of dihydropyridines in healthy subjects.
Topics: Adult; Calcium Channel Blockers; Dose-Response Relationship, Drug; Hemodynamics; Humans; Male; Nifedipine; Nisoldipine; Nitrendipine; Random Allocation | 1988 |
Calcium antagonists in the treatment of arterial hypertension in the elderly.
Topics: Age Factors; Aged; Aged, 80 and over; Calcium Channel Blockers; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Verapamil | 1986 |
Comparison of the acute hemodynamic effects of nifedipine with nitrendipine and a study of the electrophysiological effects of nitrendipine in man.
Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Electrocardiography; Electrophysiology; Heart Rate; Hemodynamics; Humans; Nifedipine; Nitrendipine; Vascular Resistance | 1984 |
Antihypertensive effects on blood pressure at rest and during exercise of calcium antagonists, beta-receptor blockers, and their combination in hypertensive patients.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Physical Exertion; Triglycerides | 1984 |
Efficacy of nitrendipine as baseline antihypertensive therapy.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Oxprenolol; Prospective Studies; Random Allocation | 1984 |
Nitrendipine in the treatment of mild to moderate hypertension.
Topics: Adult; Aged; Black People; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Random Allocation; White People | 1984 |
Clinical experience with long-term nitrendipine treatment in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Blood Proteins; Body Weight; Calcium; Calcium Channel Blockers; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Potassium; Sodium; Time Factors | 1984 |
Crossover comparison of nitrendipine with propranolol in patients with essential hypertension.
Topics: Adult; Blood Pressure; Body Weight; Calcium Channel Blockers; Catecholamines; Humans; Hypertension; Middle Aged; Nifedipine; Nitrendipine; Propranolol; Pulse; Renin; Time Factors | 1984 |
Comparison of nitrendipine combined with low-dose hydrochlorothiazide to hydrochlorothiazide alone in mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Random Allocation; Time Factors | 1984 |
Efficacy and safety comparison of nitrendipine and hydralazine as antihypertensive monotherapy.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate; Humans; Hydralazine; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Random Allocation; Time Factors | 1984 |
Bioequivalence and metabolism of nitrendipine administered orally to healthy volunteers.
Topics: Administration, Oral; Adult; Blood Pressure; Calcium Channel Blockers; Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Kinetics; Male; Nifedipine; Nitrendipine; Suspensions; Tablets; Therapeutic Equivalency | 1984 |
Calcium antagonists, firstline partners for betablockers in hypertension.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension; Nifedipine; Nitrendipine; Renin; Verapamil | 1984 |
Experience with nitrendipine--a new calcium antagonist--in hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Kinetics; Male; Middle Aged; Nifedipine; Nitrendipine; Pyridines | 1982 |
Effects of nitrendipine and hydralazine on plasma catecholamines in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Chromatography, High Pressure Liquid; Dopamine; Drug Evaluation; Epinephrine; Heart Rate; Humans; Hydralazine; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Norepinephrine; Posture | 1984 |
[Does long-term blood pressure reduction in patients with essential hypertension improve concomitant metabolic disorders?].
Topics: Adult; Blood Glucose; Blood Pressure; Body Composition; Body Mass Index; Female; Follow-Up Studies; Glucose Tolerance Test; Humans; Hypertension; Insulin; Lipids; Long-Term Care; Male; Middle Aged; Nifedipine; Nitrendipine; Triglycerides | 1994 |
Treatment of hypertensive emergency. Comparison of a new dosage form of the calcium antagonist nitrendipine with nifedipine capsules.
Topics: Administration, Oral; Adult; Aged; Capsules; Chi-Square Distribution; Double-Blind Method; Emergencies; Female; Germany; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Time Factors | 1994 |
Comparative effects of felodipine, nitrendipine and nifedipine in healthy subjects: concentration-effect relationships of racemic drugs and enantiomers.
Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Felodipine; Heart Rate; Hemodynamics; Humans; Male; Nifedipine; Nitrendipine; Protein Binding; Stereoisomerism | 1993 |
Stereoselective pharmacokinetics of oral felodipine and nitrendipine in healthy subjects: correlation with nifedipine pharmacokinetics.
Topics: Administration, Oral; Adult; Blood Proteins; Double-Blind Method; Felodipine; Half-Life; Humans; Male; Nifedipine; Nitrendipine; Pyridines; Stereoisomerism | 1993 |
Renal functional reserve in calcium channel blocker-treated hypertensive recipients of kidney transplant.
Topics: Adult; Amino Acids; Calcium Channel Blockers; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Hypertension, Renal; Isradipine; Kidney Transplantation; Male; Middle Aged; Nifedipine; Nitrendipine; Renal Plasma Flow; Retrospective Studies | 1995 |
Distinct vasodilation, without reflex neurohormonal activation, induced by barnidipine in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Reflex; Sympathetic Nervous System; Vasodilation | 1998 |
Are there any relevant differences within the calcium antagonist class?
Topics: Adolescent; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Humans; Hypertension; Middle Aged; Nifedipine; Nitrendipine; Treatment Outcome | 2000 |
475 other study(ies) available for nifedipine and nitrendipine
| Article | Year |
|---|---|
Diethyl 3,6-dihydro-2,4-dimethyl-2,6-methano-1,3-benzothiazocine-5,11- dicarboxylates as calcium entry antagonists: new conformationally restrained analogues of Hantzsch 1,4-dihydropyridines related to nitrendipine as probes for receptor-site conformation
Topics: Animals; Aorta; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Dose-Response Relationship, Drug; Heterocyclic Compounds; Ion Channels; Male; Nitrendipine; Protein Binding; Pyridines; Rats; Rats, Inbred Strains; Sarcolemma; Structure-Activity Relationship; Swine; Terpenes | 1987 |
Dihydropyrimidines: novel calcium antagonists with potent and long-lasting vasodilative and antihypertensive activity.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Dogs; Female; Heart Rate; Indicators and Reagents; Male; Molecular Structure; Pyrimidines; Rats; Rats, Inbred SHR; Receptors, Nicotinic; Structure-Activity Relationship; Vasodilator Agents | 1989 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Synthesis, platelet aggregation inhibitory activity, and in vivo antithrombotic activity of new 1,4-dihydropyridines.
Topics: Animals; Cats; Collagen; Dihydropyridines; Humans; Kinetics; Male; Mice; Nitrendipine; Platelet Aggregation; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thrombosis | 1988 |
Oxidation of 4-aryl- and 4-alkyl-substituted 2,6-dimethyl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyridines by human liver microsomes and immunochemical evidence for the involvement of a form of cytochrome P-450.
Topics: Chemical Phenomena; Chemistry; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Microsomes, Liver; NADP; Nifedipine; Oxidation-Reduction | 1986 |
Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; CHO Cells; Cricetinae; Dihydropyridines; Enzyme Inhibitors; Guinea Pigs; Humans; Isradipine; Molecular Structure; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship | 1996 |
Inhibition of thyroid hormone uptake by calcium antagonists of the dihydropyridine class.
Topics: Antithyroid Agents; Calcium Channel Blockers; Dihydropyridines; Humans; Structure-Activity Relationship; Triiodothyronine; Tumor Cells, Cultured | 1997 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Digoxin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Gene Expression; Humans; Nifedipine; Paclitaxel; RNA, Messenger; Swine; Tritium; Tumor Cells, Cultured; Verapamil; Vinblastine | 2002 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Expression and 1,4-dihydropyridine-binding properties of brain L-type calcium channel isoforms.
Topics: Amino Acid Motifs; Animals; Brain; Calcium Channels, L-Type; Dihydropyridines; Female; Gene Expression; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Protein Isoforms | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Dicarboxylic Acids; Dihydropyridines; Humans; Inhibitory Concentration 50; Molecular Structure; Nifedipine | 2010 |
Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cricetinae; Dihydropyridines; Erythrocytes; Leishmania; Macaca mulatta; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction | 2012 |
Ligand-based design, in silico ADME-Tox filtering, synthesis and biological evaluation to discover new soluble 1,4-DHP-based CFTR activators.
Topics: Absorption; Animals; Calcium Channel Blockers; Chemistry Techniques, Synthetic; Computational Biology; Cystic Fibrosis Transmembrane Conductance Regulator; Dihydropyridines; Drug Design; Humans; Ligands; Models, Molecular; Mutation; Protein Conformation; Quantitative Structure-Activity Relationship; Rats; Solubility | 2012 |
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity | 2012 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Dose-Response Relationship, Drug; Molecular Structure; N-Glycosyl Hydrolases; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Rabeprazole; Structure-Activity Relationship; Trichomonas vaginalis | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Structural Modifications of Nimodipine Lead to Novel PDE1 Inhibitors with Anti-pulmonary Fibrosis Effects.
Topics: Animals; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Idiopathic Pulmonary Fibrosis; Nimodipine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats | 2022 |
Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Dogs; Heart Rate; Hypertension; Hypertension, Renal; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Wistar | 1992 |
Changes in cardiovascular mass, left ventricular pumping ability and aortic distensibility after calcium antagonists in Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Animals; Aorta; Compliance; Heart; Heart Ventricles; Hemodynamics; Hypertension; Male; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Function, Left | 1992 |
Calcium, calcium antagonism, atherosclerosis, and ischemia.
Topics: Animals; Arteriosclerosis; Calcium; Coronary Disease; Cytosol; Humans; Hypercholesterolemia; Hypertension; Male; Nifedipine; Nitrendipine; Rabbits; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
Aging: inotropic effects of Bay K-8644 and nifedipine on rat cardiac muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Analysis of Variance; Animals; Calcium; Calcium Channels; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Rats; Rats, Inbred F344 | 1992 |
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil | 1992 |
Role of calcium channels in effects of antidepressant drugs on responsiveness to pain.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Calcium Channels; Cerebral Cortex; Chlorprothixene; Citalopram; Imipramine; Male; Membranes; Nifedipine; Nitrendipine; Pain; Pain Measurement; Rats; Rats, Inbred Strains; Reaction Time; Vasodilator Agents | 1991 |
Dihydropyridine calcium channel antagonists block and agonists potentiate high potassium contractures but not twitches in frog skeletal muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; In Vitro Techniques; Muscle Contraction; Nifedipine; Nitrendipine; Potassium; Pyridines; Rana pipiens | 1990 |
Mitochondrial Ca2+ antagonist binding sites are associated with an inner mitochondrial membrane anion channel.
Topics: Amiodarone; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Female; Guinea Pigs; Ion Channels; Male; Mitochondria; Nifedipine; Nitrates; Nitrendipine; Receptors, Nicotinic | 1990 |
Effects of calcium channel agonists (BAY K 8644, CGP28392 and YC-170) on 45Ca uptake by rat uterine segments.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Female; Nifedipine; Nitrendipine; Potassium Chloride; Pyridines; Rats; Rats, Inbred Strains; Uterus | 1991 |
The hemodynamic effects of lacidipine in anesthetized dogs: comparison with nitrendipine, amlodipine, verapamil, and diltiazem.
Topics: Amlodipine; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Stroke Volume; Vascular Resistance; Verapamil | 1991 |
Electrophysiological effects of CD-349, a dihydropyridine-type calcium antagonist, on goat cardiac Purkinje fibers.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Dihydropyridines; Electrophysiology; Goats; In Vitro Techniques; Microelectrodes; Nifedipine; Nitrendipine; Purkinje Fibers | 1991 |
The role of calcium in neutrophil migration: the effect of calcium and calcium-antagonists in electroporated neutrophils.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Caseins; Chemotaxis, Leukocyte; Egtazic Acid; Electric Stimulation; Fluorescent Dyes; In Vitro Techniques; Kinetics; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nifedipine; Nitrendipine; Prenylamine; Rabbits; Verapamil | 1992 |
In vitro effects of two novel calcium antagonists (nitrendipine and nisoldipine) on intraplatelet calcium redistribution, platelet aggregation and thromboxane A2 formation. Comparison with diltiazem, nifedipine and verapamil.
Topics: Adult; Blood Platelets; Calcium; Calcium Channel Blockers; Diltiazem; Female; Humans; In Vitro Techniques; Male; Nifedipine; Nisoldipine; Nitrendipine; Platelet Aggregation; Thromboxane A2; Thromboxane B2; Verapamil | 1991 |
Ca(2+)-channel blockers modulate expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and low density lipoprotein receptor genes stimulated by platelet-derived growth factor.
Topics: Amlodipine; Calcium Channel Blockers; Cell Division; Cell Line; Cell Membrane; DNA Replication; Fibroblasts; Gene Expression; Genes; Humans; Hydroxymethylglutaryl CoA Reductases; Kinetics; Nifedipine; Nitrendipine; Platelet-Derived Growth Factor; Receptors, LDL; RNA, Messenger; Skin; Transcription, Genetic; Verapamil | 1991 |
Short-term effects of calcium antagonists on renal haemodynamics in patients with chronic renal failure.
Topics: Adolescent; Adult; Female; Hemodynamics; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nifedipine; Nitrendipine; Renal Circulation; Time Factors | 1991 |
[Comparison of negative chronotropic action of nitrendipine, nifedipine and verapamil on the isolated right atrium of normotensive and renovascular hypertensive rats].
Topics: Animals; Atrial Function, Right; Blood Pressure; Depression, Chemical; Female; Heart Rate; Hypertension, Renovascular; In Vitro Techniques; Isometric Contraction; Male; Nifedipine; Nitrendipine; Rats; Verapamil | 1991 |
Direct measurement of intracellular free calcium in cultured human puerperal myometrial cells stimulated by oxytocin: effects of extracellular calcium and calcium channel blockers.
Topics: Calcium; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Microscopy, Fluorescence; Myometrium; Nicardipine; Nifedipine; Nitrendipine; Oxytocin; Postpartum Period | 1991 |
Different negative inotropic activity of Ca2(+)-antagonists in human myocardial tissue.
Topics: Calcium Channel Blockers; Depression, Chemical; Diltiazem; Heart Atria; Heart Failure; Heart Transplantation; Humans; Isradipine; Myocardial Contraction; Nifedipine; Nitrendipine; Papillary Muscles; Pyridines; Verapamil | 1990 |
Cortical dihydropyridine binding sites and a behavioral syndrome in morphine-abstinent rats.
Topics: Animals; Behavior, Animal; Brain Chemistry; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Dihydropyridines; Hippocampus; Male; Morphine Dependence; Naloxone; Nifedipine; Nitrendipine; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Substance Withdrawal Syndrome | 1990 |
Reactivity and sensitivity of mesenteric vascular beds and aortic rings of spontaneously hypertensive rats to endothelin: effects of calcium entry blockers.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Endothelins; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Norepinephrine; Peptides; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Splanchnic Circulation; Vasoconstriction | 1990 |
Photodegradation of nifedipine relative to nitrendipine evaluated by liquid and gas chromatography.
Topics: Chromatography, Gas; Chromatography, Liquid; Light; Nifedipine; Nitrendipine | 1990 |
Influence of age on the nocturnal fall of blood pressure and its modulation by long-acting calcium antagonists.
Topics: Aging; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Humans; Monitoring, Physiologic; Nifedipine; Nisoldipine; Nitrendipine | 1990 |
Histological and in vitro studies supporting decreased uteroplacental blood flow as explanation for digital defects after administration of vasodilators.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Extremities; Felodipine; Female; In Vitro Techniques; Limb Deformities, Congenital; Maternal-Fetal Exchange; Nifedipine; Nitrendipine; Placenta; Pregnancy; Rabbits; Vasodilator Agents | 1990 |
Effects of 1,25(OH)2D3 and calcium channel blockers on cecal calcium transport in the rat.
Topics: Animals; Biological Transport, Active; Calcitriol; Calcium; Calcium Channel Blockers; Cecum; Intestinal Absorption; Ion Channels; Male; Nifedipine; Nitrendipine; Rats; Verapamil; Vitamin D Deficiency | 1985 |
Nitrendipine potentiates Bay k 8644-induced contraction of isolated porcine coronary artery: evidence for functionally distinct dihydropyridine receptor subtypes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Coronary Vessels; Drug Synergism; In Vitro Techniques; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Receptors, Nicotinic; Swine | 1985 |
The calcium channel blocker nitrendipine blocks sodium channels in neonatal rat cardiac myocytes.
Topics: Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Electric Conductivity; Heart; Ion Channels; Membrane Potentials; Myocardium; Nifedipine; Nitrendipine; Rats; Sodium | 1985 |
High and low affinity states of the dihydropyridine and phenylalkylamine receptors on the cardiac calcium channel and their interconversion by divalent cations.
Topics: Animals; Calcium; Cations, Divalent; Chickens; Dihydropyridines; Heart; Ion Channels; Isradipine; Magnesium; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil | 1985 |
[3H]diltiazem binding to calcium channel antagonists recognition sites in rat cerebral cortex.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Calcium Channels; Cerebral Cortex; Diltiazem; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Tritium | 1985 |
Characteristics of angiotensin II-, K+- and ACTH-induced calcium influx in adrenal glomerulosa cells. Evidence that angiotensin II, K+, and ACTH may open a common calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Adrenocorticotropic Hormone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Cattle; In Vitro Techniques; Ion Channels; Kinetics; Nifedipine; Nitrendipine; Potassium | 1985 |
Role of calcium fluxes in the sustained phase of angiotensin II-mediated aldosterone secretion from adrenal glomerulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Cattle; Dantrolene; In Vitro Techniques; Ion Channels; Kinetics; Models, Biological; Nifedipine; Nitrendipine; Potassium | 1985 |
Comparative potencies of calcium channel antagonists and antischizophrenic drugs on central and peripheral calcium channel binding sites.
Topics: Animals; Antipsychotic Agents; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cerebral Cortex; In Vitro Techniques; Ion Channels; Male; Myocardium; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains | 1985 |
Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Barium; Calcium; Cobalt; Dogs; Heart Atria; Ion Channels; Isoproterenol; Kinetics; Myocardium; Nifedipine; Nitrendipine; Tetrodotoxin | 1985 |
Stimulation of calcium uptake in PC12 cells by the dihydropyridine agonist BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Calcium; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Nifedipine; Nitrendipine; Pheochromocytoma; Pyridines; Rats | 1985 |
Decreased [3H]nitrendipine binding in the brainstem of deoxycorticosterone-NaCl hypertensive rats.
Topics: Animals; Brain Stem; Calcium; Desoxycorticosterone; Dihydropyridines; Hypertension; Ion Channels; Kidney; Kinetics; Male; Myocardium; Nephrectomy; Nifedipine; Nitrendipine; Organ Size; Pyridines; Rats; Sodium Chloride | 1985 |
Profile of the oppositely acting enantiomers of the dihydropyridine 202-791 in cardiac preparations: receptor binding, electrophysiological, and pharmacological studies.
Topics: Animals; Binding, Competitive; Calcium; Dihydropyridines; Dogs; Electric Conductivity; Guinea Pigs; Heart; Ion Channels; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Papillary Muscles; Pyridines; Sarcolemma; Stereoisomerism; Ventricular Function | 1985 |
Characterization of [3H]-nitrendipine binding to uterine smooth muscle plasma membrane and its relevance to inhibition of calcium entry.
Topics: Animals; Binding, Competitive; Calcium; Cell Fractionation; Cell Membrane; Diethylstilbestrol; Diltiazem; Edetic Acid; Egtazic Acid; Female; Ion Channels; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Uterus | 1985 |
The effect of the calcium channel agonist, Bay K-8644 on human vascular smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Cell Membrane; Humans; In Vitro Techniques; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium; Serotonin; Umbilical Arteries | 1985 |
An effect of ischemia on myocardial dihydropyridine binding sites.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aerobiosis; Animals; Binding, Competitive; Calcium; Calcium Channels; Coronary Disease; In Vitro Techniques; Kinetics; Male; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Sarcolemma | 1985 |
Short term and long term effects of beta-adrenergic effectors and cyclic AMP on nitrendipine-sensitive voltage-dependent Ca2+ channels of skeletal muscle.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Alprenolol; Animals; Bucladesine; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Chick Embryo; Cyclic AMP; Ion Channels; Isoproterenol; Muscles; Nifedipine; Nitrendipine; Receptors, Nicotinic; Reserpine; Theophylline | 1985 |
Plasma membrane calcium flux, protein kinase C activation and smooth muscle contraction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cell Membrane; Colforsin; Drug Synergism; Enzyme Activation; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Ouabain; Perfusion; Phospholipids; Potassium; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Vasoconstriction | 1985 |
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cinnarizine; Diltiazem; Flunarizine; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Phenytoin; Pheochromocytoma; Potassium; Rats; Sodium; Verapamil | 1985 |
Adrenoceptors, calcium, and vasoconstriction in normal and hypertensive humans.
Topics: Arm; Blood Platelets; Blood Pressure; Calcium; Cytoplasm; Humans; Hypertension; Nifedipine; Nitrendipine; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Regional Blood Flow; Vasoconstriction | 1985 |
Calcium entry blockade and alpha-adrenergic responsiveness in vivo.
Topics: Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Hydralazine; Nifedipine; Nitrendipine; Nitroprusside; Rats; Receptors, Adrenergic, alpha; Vasoconstriction | 1985 |
In vitro comparative studies of the calcium-entry activators YC-170, CGP 28392, and BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Biological Transport; Calcium; Guinea Pigs; Heart Rate; In Vitro Techniques; Ion Channels; Male; Mesentery; Myocardial Contraction; Nifedipine; Nitrendipine; Pyridines; Rats; Vasoconstriction | 1985 |
Differential sensitivity of [3H]nitrendipine binding to cations of toxicological interest in various rat brain areas.
Topics: Animals; Brain; Calcium Channel Blockers; In Vitro Techniques; Ion Channels; Male; Metals; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Tritium | 1985 |
An increase in putative voltage dependent calcium channel number following reserpine treatment.
Topics: Animals; Catecholamines; Ion Channels; Male; Membrane Potentials; Muscle, Smooth; Nifedipine; Nitrendipine; Prazosin; Rats; Receptors, Adrenergic, alpha; Reserpine; Seminal Vesicles; Verapamil | 1985 |
Binding of the calcium antagonist [3H] nitrendipine to human myometrial plasmalemma.
Topics: Calcium; Cell Fractionation; Cell Membrane; Female; Humans; Ion Channels; Myometrium; Nifedipine; Nitrendipine | 1985 |
Participation of voltage-dependent calcium channels in the regulation of adrenal glomerulosa function by angiotensin II and potassium.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Binding, Competitive; Calcium; Cell Membrane; Corticosterone; Diltiazem; Dose-Response Relationship, Drug; Ion Channels; Male; Nifedipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Receptors, Angiotensin | 1986 |
Dietary intake of sodium chloride in the rat influences [3H]nitrendipine binding to adrenal glomerulosa cell membranes but does not alter binding to vascular smooth muscle membranes.
Topics: Adrenal Glands; Animals; Cell Membrane; Diet; Female; Ion Channels; Muscle, Smooth; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Rats; Sodium Chloride; Water-Electrolyte Balance | 1985 |
Effects of nitrendipine on the voltage-sensitive calcium channel in mammalian sensory neurons.
Topics: Action Potentials; Animals; Cells, Cultured; Dihydropyridines; Electric Stimulation; Ethanol; Ganglia, Spinal; Ion Channels; Mice; Nerve Growth Factors; Neurons, Afferent; Nifedipine; Nitrendipine; Pharmaceutical Vehicles; Pyridines; Reaction Time; Temperature | 1985 |
Dihydropyridines change the uptake of calcium induced by depolarization into primary cultures of cerebellar granule cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cells, Cultured; Cerebellum; Ion Channels; Nifedipine; Nitrendipine; Potassium Chloride; Rats; Veratridine | 1985 |
Age-dependent increase in [3H]verapamil binding to rat cortical membranes.
Topics: Age Factors; Aging; Animals; Binding, Competitive; Calcium; Cerebral Cortex; Ion Channels; Male; Membranes; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Verapamil | 1985 |
Effects of the calcium channel activator BAY-K-8644 on in vitro secretion of calcitonin and parathyroid hormone.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcitonin; Calcium; Culture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Nifedipine; Nitrendipine; Parathyroid Glands; Parathyroid Hormone; Rats; Thyroid Gland | 1986 |
The peripheral, high affinity benzodiazepine binding site is not coupled to the cardiac Ca2+ channel.
Topics: Action Potentials; Animals; Benzodiazepinones; Calcium Channel Blockers; Guinea Pigs; Heart; In Vitro Techniques; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Receptors, GABA-A | 1985 |
Effect of calcium antagonist drugs on calcium currents in mammalian skeletal muscle fibers.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; In Vitro Techniques; Ion Channels; Muscles; Nifedipine; Nitrendipine; Rabbits; Verapamil | 1986 |
Protein kinase C mediated regulation of calcium channels in PC-12 pheochromocytoma cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Calcium; Cells, Cultured; Humans; Ion Channels; Nifedipine; Nitrendipine; Norepinephrine; Pheochromocytoma; Phorbol Esters; Protein Kinase C; Synaptic Transmission; Tetradecanoylphorbol Acetate | 1986 |
Dihydropyridine and peripheral type benzodiazepine binding sites: subcellular distribution and molecular size determination.
Topics: Animals; Benzodiazepinones; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Fractionation; Dogs; Ion Channels; Isoquinolines; Isradipine; Male; Molecular Weight; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Nicotinic; Sarcolemma; Sarcoplasmic Reticulum; Verapamil | 1985 |
[3H]nitrendipine receptors as markers of a class of putative voltage-sensitive Ca2+ channels in normal human skeletal muscle and in muscle from Duchenne muscular dystrophy patients.
Topics: Calcium; Calcium Channels; Child; Child, Preschool; Humans; Ion Channels; Kinetics; Male; Muscles; Muscular Dystrophies; Nifedipine; Nitrendipine; Radioligand Assay; Receptors, Nicotinic; Syndrome | 1986 |
Motility of cultured fish epidermal cells in the presence and absence of direct current electric fields.
Topics: Animals; Calcium Channel Blockers; Cell Movement; Cells, Cultured; Cobalt; Electric Stimulation; Epidermal Cells; Epidermis; Fishes; Keratins; Lanthanum; Nifedipine; Nitrendipine; Skin; Skin Physiological Phenomena; Verapamil | 1986 |
Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bucladesine; Calcium; Cell Differentiation; Dihydropyridines; Nerve Growth Factors; Nifedipine; Nitrendipine; Norepinephrine; Pheochromocytoma; Potassium; Pyridines; Rats; Secretory Rate | 1986 |
Putative Ca2+ channels in cardiac membranes. Subcellular distribution of [3H]nitrendipine receptors.
Topics: Animals; Calcium; Calcium Channels; Cell Compartmentation; Ion Channels; Myocardium; Nifedipine; Nitrendipine; Receptors, Nicotinic; Sarcolemma; Sarcoplasmic Reticulum; Sodium; Sodium-Potassium-Exchanging ATPase; Swine | 1986 |
Enalapril in experimental hypertension and acute heart failure: comparison with calcium channel blockers.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Dogs; Drug Therapy, Combination; Enalapril; Enalaprilat; Felodipine; Heart; Heart Failure; Hypertension; Lisinopril; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR | 1986 |
Increased cardiac calcium channels in hamster cardiomyopathy.
Topics: Animals; Calcium; Calcium Channels; Cardiomyopathies; Cricetinae; Ion Channels; Kinetics; Mesocricetus; Myocardium; Nifedipine; Nitrendipine; Receptors, Nicotinic | 1986 |
Presynaptic calcium channels in rat cortical synaptosomes: fast-kinetics of phasic calcium influx, channel inactivation, and relationship to nitrendipine receptors.
Topics: Animals; Calcium; Cerebral Cortex; Ion Channels; Kinetics; Nifedipine; Nitrendipine; Osmolar Concentration; Potassium; Rats; Rats, Inbred Strains; Receptors, Drug; Sodium; Synapses; Synaptosomes; Time Factors | 1986 |
Phosphorylation and dephosphorylation of dihydropyridine-sensitive voltage-dependent Ca2+ channel in skeletal muscle membranes by cAMP- and Ca2+-dependent processes.
Topics: Animals; Binding Sites; Calcium; Calmodulin; Calmodulin-Binding Proteins; Cyclic AMP; In Vitro Techniques; Ion Channels; Muscles; Nifedipine; Nitrendipine; Phosphorylation; Protein Kinases; Rabbits; Sarcolemma | 1986 |
Mechanism of the pressor effect of the calcium agonist, BAY k 8644, in the intact rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetophenones; Animals; Arginine Vasopressin; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Catecholamines; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydrazines; Male; Nifedipine; Nisoldipine; Nitrendipine; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Saralasin; Tetrazoles | 1986 |
A polypeptide toxin from the coral Goniopora. Purification and action on Ca2+ channels.
Topics: Animals; Biological Assay; Calcium; Cells, Cultured; Chick Embryo; Chromatography, Gel; Dose-Response Relationship, Drug; Heart; Intercellular Signaling Peptides and Proteins; Ion Channels; Mice; Myocardium; Nifedipine; Nitrendipine; Peptides; Tetrodotoxin | 1986 |
Alterations in the plasma membrane properties of the myocardium of spontaneously hypertensive rats.
Topics: Adenosine Triphosphatases; Animals; Cardiomegaly; Cell Membrane; Ion Channels; Male; Myocardium; Nifedipine; Nitrendipine; Ouabain; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Sodium-Potassium-Exchanging ATPase | 1986 |
Binding of Ca2+ entry blockers to cardiac sarcolemmal membrane vesicles. Characterization of diltiazem-binding sites and their interaction with dihydropyridine and aralkylamine receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Diltiazem; Dithiothreitol; Ethylmaleimide; Female; Guinea Pigs; Hydrogen-Ion Concentration; Iodocyanopindolol; Male; Myocardium; Nifedipine; Nitrendipine; Ouabain; Pindolol; Receptors, Nicotinic; Sodium; Sodium-Potassium-Exchanging ATPase; Stereoisomerism; Temperature; Verapamil | 1986 |
Participation of voltage-dependent calcium channels in the action of gonadotropin-releasing hormone.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Animals; Calcimycin; Calcium; Cells, Cultured; Cytoplasm; Ethers; Female; Fluorescent Dyes; Gonadotropin-Releasing Hormone; Ion Channels; Ionomycin; Luteinizing Hormone; Nifedipine; Nitrendipine; Pituitary Gland, Anterior; Potassium; Rats; Rats, Inbred Strains | 1986 |
Calcium channel, Ca++ mobilization, and mechanical reactivity of estrogen- and progesterone-treated rat uterus.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Estradiol; Female; In Vitro Techniques; Ion Channels; Kinetics; Nifedipine; Nitrendipine; Potassium; Progesterone; Rats; Receptors, Nicotinic; Uterine Contraction; Uterus; Verapamil | 1986 |
Calcium utilization by dispersed canine gastric smooth muscle cells.
Topics: Animals; Calcium; Carbachol; Dogs; Egtazic Acid; Female; Gastric Mucosa; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; Pentagastrin; Potassium Chloride; Proglumide; Time Factors | 1986 |
Calcium channels in muscle cells isolated from rat mesenteric arteries: modulation by dihydropyridine drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Pyridines; Rats | 1986 |
Depolarization-dependent binding of the calcium channel antagonist, (+)-[3H]PN200-110, to intact cultured PC12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Blockers; Cells, Cultured; Isradipine; Kinetics; Membrane Potentials; Nifedipine; Nitrendipine; Onium Compounds; Organophosphorus Compounds; Oxadiazoles; Potassium; Pyridines; Tritium | 1986 |
[3H]-tetrodotoxin binding in neuronal and non-neuronal spinal cord cultures.
Topics: Animals; Binding, Competitive; Cells, Cultured; Ion Channels; Mice; Neuroglia; Neurons; Nifedipine; Nitrendipine; Spinal Cord; Tetrodotoxin | 1986 |
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Felodipine; Female; Gallic Acid; Methylation; Mice; Monensin; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Thromboplastin; Trophoblasts; Tubercidin; Verapamil | 1986 |
Do calcium antagonists act directly on calcium channels to alter baroreceptor function?
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Ion Channels; Nifedipine; Nimodipine; Nitrendipine; Pressoreceptors; Rats; Rats, Inbred Strains; Verapamil | 1986 |
MDL 72567, a dihydropyridine calcium-antagonist, that causes vasodilation and direct sinus bradycardia.
Topics: Animals; Bradycardia; Calcium Channel Blockers; Calcium Channels; Decerebrate State; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Guinea Pigs; Hypertension, Renal; Male; Nicotinic Acids; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Vasodilation | 1987 |
Action of dihydropyridine Ca-channel-modulators on isolated heart preparations.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Coronary Vessels; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Vasodilation | 1987 |
Pharmacologic relevance of dihydropyridine binding sites in membranes from rat aorta: kinetic and equilibrium studies.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Binding, Competitive; Calcium; Calcium Channels; Ion Channels; Isradipine; Kinetics; Muscle, Smooth, Vascular; Nifedipine; Nisoldipine; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Stereoisomerism | 1988 |
Regulation by chronic drug administration of neuronal and cardiac calcium channel, beta-adrenoceptor and muscarinic receptor levels.
Topics: Animals; Atropine; Brain; Calcium; Heart; Ion Channels; Male; Nifedipine; Nitrendipine; Propranolol; Rats; Receptors, Adrenergic, beta; Receptors, Muscarinic | 1988 |
The effects of chemically and electrically-induced convulsions on [3H]nitrendipine binding in mouse brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzodiazepinones; Brain; Calcium Channels; Convulsants; Electroshock; Kinetics; Male; Mice; Mice, Inbred ICR; Nifedipine; Nitrendipine; Pentylenetetrazole; Receptors, Nicotinic; Seizures; Strychnine | 1987 |
Dihydropyridine binding sites regulate calcium influx through specific voltage-sensitive calcium channels in cerebellar granule cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Calcium Radioisotopes; Cations, Divalent; Cell Membrane; Cells, Cultured; Cerebellum; Diltiazem; Electrophysiology; Ion Channels; Neurons; Nifedipine; Nitrendipine; Potassium; Rats; Receptors, Nicotinic; Verapamil | 1988 |
New 1,4-dihydropyridines with vasoconstrictor action through activation of Ca++-channels.
Topics: Animals; Blood Pressure; Calcium; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Rabbits; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Vasoconstriction; Vasoconstrictor Agents | 1988 |
Relationship between steady-state depression of calcium-dependent action potentials and competition for binding sites by nifedipine, nitrendipine, and PY 108-068.
Topics: Action Potentials; Animals; Binding, Competitive; Calcium; Dogs; Heart; In Vitro Techniques; Myocardium; Nifedipine; Nitrendipine; Purkinje Fibers | 1987 |
Sea urchin sperm head plasma membranes: characteristics and egg jelly induced Ca2+ and Na+ uptake.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cell Fractionation; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Ion Channels; Male; Microscopy, Electron; Nifedipine; Nisoldipine; Nitrendipine; Sea Urchins; Sodium; Sodium-Potassium-Exchanging ATPase; Sperm Head; Spermatozoa | 1988 |
Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aminopyridines; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; gamma-Aminobutyric Acid; Ion Channels; Isradipine; Lanthanum; Male; Mice; Neurotransmitter Agents; Nifedipine; Nitrendipine; Oxadiazoles; Potassium; Receptors, Nicotinic; Ruthenium Red; Synaptosomes | 1988 |
Identification and characterization of [3H]nitrendipine binding sites in rat spinal cord.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Kinetics; Male; Nifedipine; Nitrendipine; Quinacrine; Rats; Rats, Inbred Strains; Spinal Cord; Trifluoperazine; Verapamil | 1988 |
Natriuretic activity of amlodipine, diltiazem, and nitrendipine in saline-loaded anesthetized dogs.
Topics: Amlodipine; Anesthesia; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Female; Hemodynamics; Natriuresis; Nifedipine; Nitrendipine; Sodium; Time Factors | 1988 |
Assessment in pig coronary artery of long-lasting and potent calcium antagonistic actions of the novel dihydropyridine derivative mepirodipine hydrochloride.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Coronary Vessels; Female; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium Chloride; Swine | 1989 |
Two calcium channels in basolateral membranes of rabbit ileal epithelial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Chlorides; Diltiazem; Egtazic Acid; Electric Conductivity; Epithelium; Ileum; Male; Nifedipine; Nitrendipine; Rabbits; Sodium; Verapamil | 1989 |
Analysis of the effects of (-) and (+) isomers of the 1,4-dihydropyridine calcium channel agonist BAY k 8644 on postrest potentiation in the canine ventricular muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Dogs; Female; Heart Ventricles; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Stereoisomerism | 1989 |
Evidence of altered dihydropyridine receptor binding capacity following cardiac transplantation.
Topics: Animals; Binding, Competitive; Calcium Channels; Dihydropyridines; Dogs; Graft Rejection; Heart Transplantation; Nifedipine; Nitrendipine; Receptors, Nicotinic; Sarcolemma; Verapamil | 1989 |
Characterization of membrane calcium channels in nonpregnant and pregnant human uterus.
Topics: Adult; Binding Sites; Calcium Channels; Cell Membrane; Female; Humans; Middle Aged; Myometrium; Nicardipine; Nifedipine; Nitrendipine; Pregnancy; Verapamil | 1989 |
Development of calcium channels in gastric smooth muscle.
Topics: Animals; Animals, Newborn; Calcium Channels; Gastric Mucosa; Male; Muscle, Smooth; Nifedipine; Nitrendipine; Rabbits; Stomach; Weaning | 1989 |
The hemodynamic properties of amlodipine in anesthetised and conscious dogs: comparison with nitrendipine and influence of beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Amlodipine; Anesthesia; Animals; Calcium Channel Blockers; Cardiac Output; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Male; Nifedipine; Nitrendipine; Propranolol; Time Factors; Vascular Resistance | 1989 |
Reversible dihydropyridine isothiocyanate binding to brain calcium channels.
Topics: Animals; Brain; Calcium; Dihydropyridines; Ion Channels; Isothiocyanates; Kinetics; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Thiocyanates | 1985 |
Electrophysiological and pharmacological evidence that peripheral type benzodiazepine receptors are coupled to calcium channels in the heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Female; Guinea Pigs; Heart; Ion Channels; Isoquinolines; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Receptors, GABA-A; Tetraethylammonium Compounds; Verapamil | 1985 |
Ryanodine as a tool to determine the contributions of calcium entry and calcium release to the calcium transient and contraction of cardiac Purkinje fibers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Aequorin; Alkaloids; Animals; Calcium; Calcium Channel Blockers; Dogs; Female; Heart Conduction System; Ion Channels; Male; Membrane Potentials; Myocardial Contraction; Nifedipine; Nitrendipine; Purkinje Fibers; Ryanodine; Sodium | 1985 |
A dihydropyridine (Bay k 8644) that enhances calcium currents in guinea pig and calf myocardial cells. A new type of positive inotropic agent.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Electric Stimulation; Female; Guinea Pigs; Ion Channels; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Nisoldipine; Nitrendipine; Purkinje Fibers; Stimulation, Chemical; Strontium; Time Factors | 1985 |
Molecular approach to the calcium channel.
Topics: Animals; Benzothiazoles; Binding Sites; Brain; Calcium; Cattle; Chemical Phenomena; Chemistry; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Muscles; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles; Thiazoles; Verapamil | 1985 |
Calcium channels in rat brain synaptosomes: identification and pharmacological characterization. High affinity blockade by organic Ca2+ channel blockers.
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Ion Channels; Male; Nifedipine; Nitrendipine; Norepinephrine; Potassium; Pyridines; Rats; Rats, Inbred Strains; Synaptosomes | 1985 |
Dihydropyridine sensitive calcium channels in a smooth muscle cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Cobalt; Dihydropyridines; Ion Channels; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium; Pyridines; Rats | 1985 |
Pharmacological evidence that the non-neuronal diazepam binding site in primary cultures of glial cells is associated with a calcium channel.
Topics: Anti-Anxiety Agents; Benzodiazepinones; Binding, Competitive; Calcium Channel Blockers; Cells, Cultured; Convulsants; Diazepam; Humans; Ion Channels; Neuroglia; Nifedipine; Nitrendipine; Receptors, GABA-A | 1985 |
[3H]Nitrendipine binding to calcium channels in bovine and rat pituitary.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cattle; In Vitro Techniques; Ion Channels; Nifedipine; Nitrendipine; Pituitary Gland; Rats; Receptors, Nicotinic; Tritium | 1985 |
Interactions of amantadine with the cardiac muscarinic receptor.
Topics: Acetylcholine; Amantadine; Animals; Binding, Competitive; Dihydroalprenolol; Electrocardiography; Guinea Pigs; Heart Atria; Heart Conduction System; Ion Channels; Myocardial Contraction; Nifedipine; Nitrendipine; Propranolol; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1985 |
The behavioral effects of the calcium agonist Bay K 8644 in the mouse: antagonism by the calcium antagonist nifedipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Behavior, Animal; Binding, Competitive; Brain; Calcium Channel Blockers; Mice; Motor Activity; Nifedipine; Nitrendipine | 1985 |
Stereospecific modulation of the calcium channel in human erythrocytes by cholesterol and its oxidized derivatives.
Topics: Calcium; Calcium Channel Blockers; Cholesterol; Erythrocytes; Humans; Ion Channels; Kinetics; Molecular Conformation; Nifedipine; Nitrendipine | 1985 |
Ethanol administration in vivo alters calcium ions control in rat striatum.
Topics: Animals; Calcium; Corpus Striatum; Ethanol; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains | 1985 |
Age-related reduced affinity in [3H]nitrendipine labeling of brain voltage-dependent calcium channels.
Topics: Age Factors; Animals; Calcium; Cerebral Cortex; Female; Ion Channels; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains | 1985 |
Effects of calcium channel blocking agents on neostigmine-induced fasciculations.
Topics: Animals; Calcium Channel Blockers; Electric Stimulation; Facial Muscles; Fasciculation; Male; Neostigmine; Nerve Endings; Nifedipine; Nitrendipine; Phenytoin; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Gas chromatographic-mass spectrometric analysis of plasma nifedipine.
Topics: Gas Chromatography-Mass Spectrometry; Humans; Male; Nifedipine; Nitrendipine; Reference Standards | 1989 |
[Pharmacologic inhibition of experimental atherosclerosis].
Topics: Animals; Arteriosclerosis; Cell Division; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Heparin; Male; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains | 1989 |
The effects of the calcium entry blockers, nilvadipine and nitrendipine, on endotoxin-induced disseminated intravascular coagulation.
Topics: Agglutination Tests; Animals; Disseminated Intravascular Coagulation; Endotoxins; Fibrin Fibrinogen Degradation Products; Fibrinogen; Injections, Intravenous; Male; Nifedipine; Nitrendipine; Platelet Count; Premedication; Rats; Rats, Inbred Strains | 1989 |
Suppression of renin-angiotensin system in the heart of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Chromatography, Liquid; Heart; Hypertension; Male; Muzolimine; Myocardium; Nifedipine; Nitrendipine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System | 1987 |
2-(2-Aryl-2-oxoethylidene)-1,2,3,4-tetrahydropyridines. Novel isomers of 1,4-dihydropyridine calcium channel blockers.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels; Coronary Vessels; Heart; In Vitro Techniques; Isomerism; Nifedipine; Nitrendipine; Pyridines; Rabbits; Rats; Receptors, Nicotinic; Structure-Activity Relationship | 1988 |
Calcium channel binding characteristics in the human heart.
Topics: Adult; Binding Sites; Calcium Channels; Female; Heart Atria; Heart Ventricles; Humans; Middle Aged; Myocardium; Nifedipine; Nitrendipine; Receptors, Cell Surface | 1988 |
Synthesis and calcium channel antagonist activity of nifedipine analogues containing 1,2-dihydropyridyl in place of the 1,4-dihydropyridyl moiety.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Intestine, Small; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; Structure-Activity Relationship | 1988 |
Calcium entry blockade by nitrendipine and alpha adrenergic responsiveness in vivo: comparison of systemic vs. local effects.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Imidazoles; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reserpine; Vasoconstriction | 1985 |
Effect of dantrolene sodium on [3H]nitrendipine binding to rat cardiac plasma membranes.
Topics: Animals; Calcium Channel Blockers; Cell Membrane; Dantrolene; In Vitro Techniques; Male; Myocardium; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains | 1985 |
Stereoselective interactions of 2-[(2',6'-dimethoxyphenoxyethyl)aminomethyl]-1,4-benzodioxane (WB-4101) with the calcium channel.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Calcium Channels; Dioxanes; Dioxins; In Vitro Techniques; Male; Myocardium; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Stereoisomerism; Thermodynamics | 1986 |
Comparison of calcium antagonists with other antihypertensive agents.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Nitrendipine; Verapamil | 1986 |
QSAR of binding of dihydropyridine-type calcium antagonists to their receptor on ileal smooth muscle preparations.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Guinea Pigs; Ileum; Mathematics; Muscle, Smooth; Nifedipine; Nitrendipine; Pyridines; Receptors, Nicotinic; Structure-Activity Relationship | 1986 |
Mechanisms of alpha-adrenoceptor mediated contractions of rat mesenteric artery.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Clonidine; In Vitro Techniques; Kinetics; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction; Verapamil | 1986 |
Regional distribution of [3H]nitrendipine binding in human brain.
Topics: Adult; Aged; Brain; Calcium Channel Blockers; Female; Humans; Male; Middle Aged; Nifedipine; Nitrendipine | 1985 |
Specific binding of [3H]d-cis-diltiazem to cardiac sarcolemma and its inhibition by calcium.
Topics: Animals; Benzazepines; Binding, Competitive; Calcium; Diltiazem; Dogs; In Vitro Techniques; Kinetics; Myocardium; Nifedipine; Nitrendipine; Sarcolemma; Stereoisomerism | 1985 |
Phencyclidine increases the affinity of dihydropyridine calcium channel antagonist binding in rat brain.
Topics: Animals; Binding Sites; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Kinetics; Magnesium; Male; Nifedipine; Nitrendipine; Phencyclidine; Pyridines; Rats; Rats, Inbred Strains | 1985 |
The effect of a calcium antagonist, nitrendipine, on the responses of isolated strips of human, chorionic plate artery to prostaglandins E2 and E1.
Topics: Alprostadil; Arteries; Calcium Channel Blockers; Cesarean Section; Chorion; Dinoprostone; Female; Humans; In Vitro Techniques; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Random Allocation; Vasoconstriction | 1985 |
Calcium channel antagonist binding and pharmacology in rat uterine smooth muscle.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Cell Membrane; Female; In Vitro Techniques; Muscle, Smooth; Myometrium; Nifedipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Uterine Contraction | 1985 |
[Nitrendipine, a new calcium antagonist, in the therapy of arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Time Factors | 1985 |
Hemodynamic effects of calcium entry-blocking agents in normal and hypertensive rats and man.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vascular Resistance | 1985 |
Effects of the calcium-channel agonist CGP 28392 on insulin secretion from isolated rat islets of Langerhans.
Topics: Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nifedipine; Nitrendipine; Norepinephrine; Pyridines; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1985 |
Long-term effects of nitrendipine on hemodynamics and oxygen transport in patients with cor pulmonale.
Topics: Aged; Biological Transport; Female; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Nitrendipine; Oxygen; Pulmonary Heart Disease | 1986 |
Nitrendipine, a calcium-entry blocker. Renal and humoral effects in human arterial hypertension.
Topics: Adult; Aged; Aldosterone; Blood Volume; Body Fluids; Calcium Channel Blockers; Catecholamines; Electrolytes; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Nifedipine; Nitrendipine; Renin | 1986 |
Hypotensive effects of dihydropyridine derivatives.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Hydralazine; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1985 |
Effect of neuraminidase on diltiazem-mediated alteration of nitrendipine binding in the hog coronary artery.
Topics: Animals; Benzazepines; Coronary Vessels; Diltiazem; In Vitro Techniques; Kinetics; Membranes; Muscle, Smooth, Vascular; Neuraminidase; Nifedipine; Nitrendipine; Swine | 1985 |
[Calcium antagonists in the therapy of essential arterial hypertension. Analysis of the results obtained with 3 drugs].
Topics: Adult; Aged; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Propylamines; Tiapamil Hydrochloride | 1985 |
Pharmacologic levels of nitrendipine do not affect actin-myosin interaction in the human uterus and placenta.
Topics: Actins; Actomyosin; Adenosine Triphosphatases; Adenosine Triphosphate; Calcium Channel Blockers; Female; Humans; In Vitro Techniques; Muscle, Smooth; Myosins; Nifedipine; Nitrendipine; Phosphorylation; Placenta; Pregnancy; Uterus | 1986 |
[Medium-term use of nitrendipine in the treatment of essential arterial hypertension].
Topics: Adult; Antihypertensive Agents; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine | 1985 |
Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats.
Topics: Animals; Cardiomegaly; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Hypoxia; Male; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Pulmonary Circulation; Rats; Rats, Inbred Strains | 1986 |
Comparative study of coronary vasodilator and cardiac effects of nitrendipine by use of isolated, blood-perfused dog heart preparations.
Topics: Animals; Atrioventricular Node; Coronary Circulation; Dogs; Female; Heart; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Papillary Muscles; Sinoatrial Node; Vasodilator Agents | 1986 |
Haemodynamic effects of vasodilating drugs on the common carotid and brachial circulations of patients with essential hypertension.
Topics: Administration, Oral; Adult; Aged; Blood Flow Velocity; Brachial Artery; Captopril; Carotid Arteries; Female; Heart Rate; Humans; Hypertension; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Nitrendipine; Regional Blood Flow; Rheology; Vascular Resistance; Vasodilator Agents | 1986 |
Effects of bepridil and diltiazem on [3H]nitrendipine binding to canine cardiac sarcolemma. Potentiation of pharmacological effects of nitrendipine by bepridil.
Topics: Animals; Benzazepines; Bepridil; Binding Sites; Binding, Competitive; Diltiazem; Dogs; Drug Synergism; In Vitro Techniques; Kinetics; Myocardial Contraction; Nifedipine; Nitrendipine; Pyrrolidines; Rats; Sarcolemma; Temperature | 1986 |
Distribution of 3H-nitrendipine in the isolated perfused rat heart as revealed by electron microscopic autoradiography.
Topics: Animals; Autoradiography; Capillaries; Cell Membrane; Coronary Vessels; Endothelium; In Vitro Techniques; Male; Microscopy, Electron; Microtubules; Mitochondria, Heart; Myocardial Contraction; Myocardium; Myofibrils; Nifedipine; Nitrendipine; Perfusion; Rats | 1986 |
[Prevention of the cardiotoxicity of cocaine using a calcium blocker].
Topics: Animals; Cardiomyopathies; Cocaine; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains | 1985 |
Protective action of calcium entry blockers in endotoxin shock.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Escherichia coli; Heart Rate; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Shock, Septic; Verapamil | 1986 |
Calcium channel antagonists. Omega-conotoxin defines a new high affinity site.
Topics: Animals; Binding, Competitive; Brain; Calcium Channel Blockers; Chick Embryo; Cinnarizine; Diltiazem; Flunarizine; Muscles; Nifedipine; Nitrendipine; Prenylamine; Rana pipiens; Synaptosomes; Time Factors; Verapamil | 1986 |
Enhancement of brain calcium antagonist binding by phencyclidine and related compounds.
Topics: Anesthetics, Local; Animals; Binding Sites; Brain; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Male; Narcotics; Neurotoxins; Nifedipine; Nitrendipine; Phencyclidine; Rats; Rats, Inbred Strains | 1986 |
[H3]-nitrendipine binding in non-neuronal cell cultures.
Topics: Animals; Astrocytes; Binding Sites; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Glial Fibrillary Acidic Protein; Mice; Neurons; Nifedipine; Nitrendipine; Oligodendroglia; Spinal Cord | 1986 |
The effects of some slow channel blocking drugs on high affinity serotonin uptake by rat brain synaptosomes.
Topics: Animals; Bepridil; Brain; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Pyrrolidines; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes; Temperature; Time Factors; Verapamil | 1986 |
Binding of [3H]nitrendipine to cardiac and cerebral membranes from normotensive and renal, deoxycorticosterone/NaCl and spontaneously hypertensive rats.
Topics: Animals; Binding Sites; Brain; Desoxycorticosterone; Hypertension; Hypertension, Renal; In Vitro Techniques; Male; Myocardium; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride | 1986 |
Cell cycle dependence of calmodulin levels during HL-60 proliferation and myeloid differentiation. No changes during pre-commitment.
Topics: Calmodulin; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Humans; Leukemia, Myeloid, Acute; Nifedipine; Nitrendipine; Trifluoperazine; Verapamil | 1986 |
Nitrendipine, nifedipine and verapamil inhibit the in vitro formation of irreversibly sickled cells.
Topics: Adult; Anemia, Sickle Cell; Calcium; Calcium Channel Blockers; Calmodulin; Dehydration; Erythrocytes, Abnormal; Humans; In Vitro Techniques; Lanthanum; Nifedipine; Nitrendipine; Phosphodiesterase Inhibitors; Potassium; Verapamil; Zinc | 1986 |
Agonist-induced calcium transients in cultured smooth muscle cells: measurements with fura-2 loaded monolayers.
Topics: Aminoquinolines; Angiotensin II; Animals; Arginine Vasopressin; Benzofurans; Calcium; Carbachol; Cell Line; Cricetinae; Ethers; Fura-2; Ionomycin; Male; Mesocricetus; Muscle, Smooth; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Norepinephrine; Rabbits; Serotonin; Vasopressins | 1986 |
Regional modification of brain calcium antagonist binding after in vivo chronic lead exposure.
Topics: Animals; Binding Sites; Brain; Calcium; Drug Interactions; Female; Lead; Maternal-Fetal Exchange; Nifedipine; Nitrendipine; Organometallic Compounds; Pregnancy; Rats; Rats, Inbred Strains; Synaptic Membranes; Tritium | 1986 |
[3H]Nitrendipine binding sites are decreased in the substantia nigra and striatum of the brain from patients with Parkinson's disease.
Topics: Aged; Binding Sites; Caudate Nucleus; Corpus Striatum; Female; Globus Pallidus; Humans; Male; Nifedipine; Nitrendipine; Parkinson Disease; Putamen; Substantia Nigra | 1986 |
Interactions among membrane transport systems: anthracyclines, calcium antagonists and anti-estrogens.
Topics: Animals; Antibiotics, Antineoplastic; Biological Transport; Calcium Channel Blockers; Daunorubicin; Doxorubicin; Drug Resistance; Estrogen Antagonists; Kinetics; Leukemia P388; Mice; Naphthacenes; Nifedipine; Nitrendipine; Tamoxifen; Verapamil | 1986 |
Nitrendipine enhances the effect of adrenaline on serum potassium in normal man.
Topics: Calcium Channel Blockers; Drug Synergism; Epinephrine; Humans; Nifedipine; Nitrendipine; Potassium | 1986 |
Augmentation by calcium channel antagonists of general anaesthetic potency in mice.
Topics: Anesthesia, General; Animals; Argon; Calcium Channel Blockers; Cinnarizine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Flunarizine; Male; Mice; Nifedipine; Nitrendipine; Pentobarbital; Time Factors; Verapamil | 1986 |
[Therapeutic effect of nitrendipine in the treatment of systemic hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine | 1986 |
[Nitrendipine in the treatment of elderly hypertensive patients. Study of observations on effectiveness and tolerance].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine | 1986 |
Effect of nitrendipine, diltiazem, trifluoperazine and pimozide on serotonin2 (5-HT2) receptor activation in the rat uterus and jugular vein.
Topics: Animals; Benzazepines; Calcium; Cerebral Cortex; Diltiazem; Female; In Vitro Techniques; Jugular Veins; Male; Nifedipine; Nitrendipine; Pimozide; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Trifluoperazine; Uterine Contraction; Vasoconstriction | 1986 |
Acylating phencyclidines irreversibly enhance brain calcium antagonist binding.
Topics: Animals; Brain; Male; Membranes; Mice; Mice, Inbred ICR; Nifedipine; Nitrendipine; Phencyclidine; Stimulation, Chemical | 1986 |
[Comparative effects of dihydropyridine inhibitors of calcium penetration on spontaneous contraction of the isolated heart atria in the guinea pig].
Topics: Aminophylline; Animals; Atrial Function; Calcium; Calcium Chloride; Depression, Chemical; Drug Interactions; Female; Guinea Pigs; Isoproterenol; Male; Myocardial Contraction; Nicardipine; Nifedipine; Nitrendipine | 1988 |
Effect of membrane depolarization on binding of [3H]nitrendipine to rat cardiac myocytes.
Topics: Aconitine; Animals; Binding Sites; Binding, Competitive; Calcium Channels; Cell Survival; Diltiazem; Heart; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Myocardium; Nifedipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Verapamil | 1985 |
Autoradiographic localization of calcium channel antagonist receptors in rat brain with [3H]nitrendipine.
Topics: Animals; Autoradiography; Brain; Calcium Channels; In Vitro Techniques; Limbic System; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Synapses; Thalamus | 1985 |
Identification of calcium-channel receptors in intact animals.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Dose-Response Relationship, Drug; Ileum; Liver; Lung; Male; Muscle, Smooth, Vascular; Muscles; Myocardium; Nifedipine; Nitrendipine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Nicotinic | 1985 |
Non-invasive measurements of cell surface receptors.
Topics: Animals; Binding, Competitive; Calcium Channels; Cells, Cultured; Heart Rate; Kinetics; Membrane Proteins; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Rats; Receptors, Drug; Receptors, Nicotinic | 1985 |
Calcium entry blockade by nitrendipine and alpha adrenergic responsiveness in vivo: comparison with noncalcium entry blocker vasodilators in absence and presence of phenoxybenzamine pretreatment.
Topics: Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Hydralazine; Methoxamine; Nifedipine; Nitrendipine; Nitroprusside; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasodilator Agents | 1985 |
Subcellular localization of [3H]-nitrendipine binding sites in guinea-pig ileal smooth muscle.
Topics: 5'-Nucleotidase; Animals; Binding Sites; Binding, Competitive; Cell Fractionation; Cell Membrane; Digitonin; Female; Guinea Pigs; Ileum; Microsomes; Mitochondria; Muscle, Smooth; Nifedipine; Nitrendipine; Nucleotidases; Ouabain | 1985 |
Ca2+ channel antagonist actions in bladder smooth muscle: comparative pharmacologic and [3H]nitrendipine binding studies.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Gallopamil; Guinea Pigs; In Vitro Techniques; Male; Microsomes; Muscarine; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Urinary Bladder | 1985 |
The influence of CGP 28392, a 1,4-dihydropyridine, on human platelet calcium and cyclic AMP metabolism.
Topics: Alprostadil; Blood Platelets; Calcium; Calcium Channel Blockers; Cyclic AMP; Humans; In Vitro Techniques; Kinetics; Nifedipine; Nitrendipine; Phosphorylation; Protein Kinases; Pyridines | 1985 |
Inhibition of [3H]nitrendipine binding by phospholipase A2.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bee Venoms; Binding Sites; Brain; Calcium Channels; Cell Membrane; Female; Guinea Pigs; Ileum; Intercellular Signaling Peptides and Proteins; Male; Muscles; Myocardium; Nifedipine; Nitrendipine; Peptides; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Snake Venoms; Time Factors; Viper Venoms; Wasp Venoms | 1985 |
Modification of cardiac sarcolemmal Na+-Ca2+ exchange by diltiazem and verapamil.
Topics: Acebutolol; Animals; Benzazepines; Ca(2+) Mg(2+)-ATPase; Calcium; Diltiazem; In Vitro Techniques; Myocardium; Nifedipine; Nitrendipine; Propranolol; Rats; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1985 |
Effect of lanthanum on the inotropic response of isoproterenol: role of the superficially bound calcium.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cyclic AMP; Female; Guinea Pigs; Heart; Isoproterenol; Lanthanum; Male; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Receptors, Nicotinic | 1985 |
Ion pathways in transverse tubules. Quantification of receptors in membranes isolated from frog and rabbit skeletal muscle.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anura; Bungarotoxins; Calcium Channels; Carrier Proteins; Diltiazem; Ethylenediamines; Kinetics; Muscles; Nifedipine; Nitrendipine; Ouabain; Rabbits; Receptors, Cholinergic; Receptors, Drug; Receptors, Nicotinic; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Temperature; Tetrodotoxin | 1986 |
Phorbol esters inhibit alpha 1-adrenergic receptor-stimulated phosphoinositide hydrolysis and contraction in rat aorta: evidence for a link between vascular contraction and phosphoinositide turnover.
Topics: Animals; Hydrolysis; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Norepinephrine; Phorbol Esters; Phosphatidylinositols; Rats; Receptors, Adrenergic, alpha; Vasomotor System | 1986 |
Voltage-sensitive nitrendipine binding in an isolated cardiac sarcolemma preparation.
Topics: Animals; Dogs; Electrophysiology; Kinetics; Mathematics; Membrane Potentials; Myocardium; Nifedipine; Nitrendipine; Ouabain; Potassium; Sarcolemma; Sodium Dodecyl Sulfate; Sodium-Potassium-Exchanging ATPase; Valinomycin | 1986 |
Dihydropyridine [methyl-3H]PN 200-110 binding and myogenesis in intact muscle cells in vitro.
Topics: Aminoquinolines; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Chick Embryo; Isradipine; Kinetics; Muscles; Nifedipine; Nitrendipine; Oxadiazoles; Receptors, Nicotinic | 1986 |
Calcium antagonist receptors in cardiomyopathic hamster: selective increases in heart, muscle, brain.
Topics: Animals; Brain; Brain Chemistry; Calcium; Calcium Channels; Cardiomyopathy, Hypertrophic; Cricetinae; Disease Models, Animal; Female; Heart; Male; Mesocricetus; Muscle, Smooth; Muscles; Myocardium; Nifedipine; Nitrendipine; Receptors, Nicotinic; Synaptosomes; Verapamil | 1986 |
Developmental changes of Ca++ transport systems in chick heart.
Topics: Age Factors; Animals; Biological Transport; Calcium; Chick Embryo; Heart; Mitochondria, Heart; Nifedipine; Nitrendipine; Sarcolemma; Sarcoplasmic Reticulum; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Dihydropyridine calcium channel antagonists binding in non-mammalian vertebrates: characterization and relationship to 'peripheral-type' binding sites for benzodiazepines.
Topics: Animals; Brain; Calcium Channels; Columbidae; Dihydropyridines; Female; Kinetics; Lizards; Male; Membranes; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rana catesbeiana; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Nicotinic; Species Specificity; Trout | 1986 |
High-affinity antibodies to the 1,4-dihydropyridine Ca2+-channel blockers.
Topics: Animals; Antibodies; Antibody Specificity; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Nifedipine; Nitrendipine; Pyridines; Rabbits; Receptors, Nicotinic; Structure-Activity Relationship; Tritium | 1986 |
Novel interactions of cations with dihydropyridine calcium antagonist binding sites in brain.
Topics: Animals; Binding Sites; Brain; Calcium; Calcium Channels; Cations; Kinetics; Lithium; Magnesium; Male; Manganese; Myocardium; Nifedipine; Nitrendipine; Osmolar Concentration; Potassium; Rats; Receptors, Nicotinic; Rubidium; Sodium; Tromethamine | 1986 |
Ineffectiveness of organic calcium channel blockers in antagonizing long-term potentiation.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Cinnarizine; Diazepam; Flunarizine; Guinea Pigs; Hippocampus; Neurons; Nifedipine; Nitrendipine; Reaction Time; Synaptic Transmission; Verapamil | 1986 |
Stereoselectivity of a potent calcium antagonist, 1-benzyl-3-pyrrolidinyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
Topics: Animals; Blood Pressure; Brain; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Coronary Circulation; Coronary Vessels; Dogs; Heart Rate; Male; Molecular Conformation; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship; Vasodilation | 1986 |
Effects of oxygen free radical scavengers, xanthine oxidase inhibition and calcium entry-blockers on leakage of albumin after ischaemia. An experimental study in rabbit kidneys.
Topics: Allopurinol; Animals; Calcium Channel Blockers; Capillary Permeability; Catalase; Felodipine; Free Radicals; Ischemia; Kidney; Mannitol; Nifedipine; Nitrendipine; Oxygen; Rabbits; Serum Albumin, Radio-Iodinated; Superoxide Dismutase; Xanthine Oxidase | 1988 |
Phosphorylation of ventricular sarcolemmal membranes does not alter binding properties of nitrendipine.
Topics: Alamethicin; Animals; Cats; Dihydropyridines; Dose-Response Relationship, Drug; Female; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Phosphorylation; Protein Kinases; Pyridines; Sarcolemma; Time Factors | 1985 |
[3H]-Nitrendipine binding in developing dissociated fetal mouse spinal cord neurons.
Topics: Animals; Female; Kinetics; Mice; Neurons; Nifedipine; Nitrendipine; Pregnancy; Spinal Cord; Time Factors | 1985 |
Effects of mercaptans upon dihydropyridine binding sites on transverse tubules isolated from triads of rabbit skeletal muscle.
Topics: Animals; Digoxin; Dihydropyridines; Dithiothreitol; Glutathione; Glutathione Disulfide; Muscles; Nifedipine; Nitrendipine; Ouabain; Pyridines; Rabbits; Sulfhydryl Compounds | 1985 |
Interference of sodium with [3H]-nitrendipine binding to cardiac membranes.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Cerebral Cortex; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Membranes; Muscles; Myocardium; Nifedipine; Nitrendipine; Sodium | 1985 |
Renal hemodynamic and tubular transport effects of nitrendipine.
Topics: Administration, Oral; Diuresis; Electrolytes; Glomerular Filtration Rate; Humans; Infusions, Parenteral; Kidney; Male; Nifedipine; Nitrendipine; Renal Circulation; Sodium; Water | 1985 |
Specific binding of the calcium antagonist [3H]verapamil to membrane fractions from plants.
Topics: Binding Sites; Diltiazem; Hydrogen-Ion Concentration; Kinetics; Membranes; Nifedipine; Nitrendipine; Plants; Verapamil | 1985 |
Quantification of nitrendipine in plasma by a capillary column gas chromatographic-mass spectrometric method.
Topics: Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Kinetics; Nifedipine; Nitrendipine; Spectrophotometry, Ultraviolet; Time Factors | 1985 |
Cardiac hypertrophy and arterial distensibility in essential hypertension.
Topics: Adult; Aged; Arteries; Blood Flow Velocity; Cardiomegaly; Humans; Hypertension; Middle Aged; Nifedipine; Nitrendipine; Pyridazines; Stroke Volume; Vascular Resistance | 1985 |
Effects of dihydropyridine derivatives and anticonvulsant drugs on [3H]nitrendipine binding and calcium and sodium fluxes in brain.
Topics: Animals; Anticonvulsants; Barbiturates; Brain; Calcium; Ethanol; In Vitro Techniques; Kinetics; Male; Nifedipine; Nitrendipine; Phenytoin; Rats; Rats, Inbred Strains; Sodium; Tritium | 1985 |
The influence of monotherapy with oxprenolol and nitrendipine on ambulatory blood pressure in hypertensives.
Topics: Adult; Ambulatory Care; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Oxprenolol | 1985 |
Effects of chronic nitrendipine on casual (office) and 24-hour ambulatory blood pressure.
Topics: Adult; Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Posture; Sleep | 1985 |
The protective effect of nitrendipine on gentamicin acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Hemodynamics; Kidney; Kidney Diseases; Kidney Function Tests; Male; Nifedipine; Nitrendipine; Polyethylene Glycols; Rats | 1985 |
The mechanism of binding of dihydropyridine calcium channel blockers to rat brain membranes.
Topics: Animals; Brain; Calcium Channel Blockers; Isomerism; Isradipine; Kinetics; Mathematics; Nifedipine; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Potent enhancement of [3H]nitrendipine binding in rat cerebral cortical and cardiac homogenates: a putative mechanism for the action of MDL 12,330A.
Topics: Animals; Calcium Channel Blockers; Cerebral Cortex; Half-Life; Heart; Imines; In Vitro Techniques; Kinetics; Male; Myocardium; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Temperature; Tritium | 1985 |
[Nitrendipine, a new calcium antagonist, as basis therapy in essential hypertension].
Topics: Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; Hypertension; Middle Aged; Nifedipine; Nitrendipine | 1985 |
Atrotoxin: a specific agonist for calcium currents in heart.
Topics: Action Potentials; Animals; Calcium; Cell Membrane; Crotalid Venoms; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Molecular Weight; Myocardium; Nifedipine; Nitrendipine; Potassium; Rats; Sodium | 1985 |
Nitrendipine kinetics in normal and impaired renal function.
Topics: Adult; Aged; Antihypertensive Agents; Biotransformation; Creatinine; Humans; Intestinal Absorption; Kidney Diseases; Kinetics; Male; Middle Aged; Models, Biological; Nifedipine; Nitrendipine | 1985 |
Studies of [3H]nitrendipine binding and KCl-induced calcium uptake in rat cortical synaptosomes.
Topics: Animals; Calcium; Calcium Channel Blockers; Cerebral Cortex; Cinnarizine; Flunarizine; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes | 1985 |
A calcium-channel blocker as antidote to the cardiac effects of cocaine intoxication.
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Cocaine; Dogs; Nifedipine; Nitrendipine; Rats | 1985 |
Age related antihypertensive effect of nitrendipine, a new calcium entry blocking agent.
Topics: Adult; Age Factors; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Middle Aged; Nifedipine; Nitrendipine | 1985 |
Nitrendipine-induced stimulation of renin release by the isolated perfused rat kidney.
Topics: Angiotensin I; Animals; In Vitro Techniques; Kidney; Kinetics; Nifedipine; Nitrendipine; Perfusion; Radioimmunoassay; Rats; Renin | 1985 |
Manganese can inhibit or potentiate contractile responses in mesenteric portal vein.
Topics: Animals; Barium; Calcium; Felodipine; Gallopamil; In Vitro Techniques; Male; Manganese; Mesenteric Veins; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Spectrophotometry, Atomic; Strontium; Tissue Distribution; Verapamil | 1988 |
Slow dissociation of the new slow-onset and long-acting calcium antagonist benidipine hydrochloride from 3H-nitrendipine binding sites.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Male; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred Strains | 1988 |
Antihypertensive effects of intravenous administration of benidipine hydrochloride and some other calcium antagonists in conscious, spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intravenous; Male; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Verapamil | 1988 |
Antihypertensive effects of the new calcium antagonist benidipine hydrochloride in conscious, renal-hypertensive dogs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dogs; Female; Heart Rate; Hypertension, Renal; Male; Nicardipine; Nifedipine; Nitrendipine; Propranolol | 1988 |
Sensitive radioreceptor assay of the calcium antagonist benidipine hydrochloride in plasma and urine.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Dogs; Male; Molecular Structure; Nifedipine; Nitrendipine; Radioligand Assay; Rats; Regression Analysis | 1988 |
Effect of nifedipine on the shuttlebox escape deficit induced by inescapable shock in the rat.
Topics: Animals; Binding Sites; Brain; Depression; Electroshock; Escape Reaction; Imipramine; Kinetics; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Verapamil | 1988 |
Effects of nifedipine and felodipine on adenosine and inosine release from the hypoxemic rat cerebral cortex.
Topics: Adenosine; Animals; Cerebral Cortex; Felodipine; Hypoxia, Brain; Inosine; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains | 1988 |
High performance liquid chromatography of a new 1,4-dihydropyridine: applications to pharmacokinetic study in dogs.
Topics: Administration, Oral; Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dogs; Indicators and Reagents; Injections, Intravenous; Light; Male; Nicardipine; Nifedipine; Nitrendipine | 1988 |
Comparison of the effects of calcium channel blockers and antiarrhythmic drugs on digitalis-induced oscillatory afterpotentials on canine Purkinje fiber.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Digitalis; Diltiazem; Dogs; Electric Stimulation; Female; Heart Conduction System; Male; Mexiletine; Nicardipine; Nifedipine; Nitrendipine; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Purkinje Fibers; Verapamil | 1987 |
[Comparative studies on the antihypertensive effects of m-nifedipine, nifedipine and nitrendipine in conscious rats and rabbits].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Hypertension, Renovascular; Male; Nifedipine; Nitrendipine; Rabbits; Rats; Rats, Inbred Strains | 1987 |
The use of calcium antagonists in patients with renal failure.
Topics: Calcium Channel Blockers; Diltiazem; Humans; Kidney Failure, Chronic; Nifedipine; Nitrendipine; Verapamil | 1987 |
Central administration of benzodiazepines alters water absorption by the rat ileum in vivo.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; Ileum; Injections, Intraventricular; Intestinal Absorption; Lorazepam; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Water | 1987 |
[Increase of the depressive effect of verapamil in acidosis].
Topics: Acidosis; Animals; Depression, Chemical; Heart Atria; Hydrogen-Ion Concentration; Myocardial Contraction; Nifedipine; Nitrendipine; Rats; Sinoatrial Node; Verapamil | 1986 |
Low potency of Ca antagonists in smooth muscle from different levels of the respiratory tract.
Topics: Animals; Bronchi; Calcium Channel Blockers; Felodipine; Female; Gallopamil; Guinea Pigs; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Respiratory Muscles; Trachea; Verapamil | 1987 |
Dihydropyridine calcium antagonists depress the amplitude of the plasma melatonin cycle in baboons.
Topics: Animals; Calcium Channel Blockers; Male; Melatonin; Nifedipine; Nisoldipine; Nitrendipine; Papio; Verapamil | 1986 |
The interaction of phenylalkylamine calcium channel blockers with the 1,4-dihydropyridine binding site.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Dihydropyridines; Heart; Kinetics; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Drug; Structure-Activity Relationship; Verapamil | 1986 |
Felodipine compared to nifedipine as "third-line drug" in resistant hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Drug Evaluation; Drug Resistance; Felodipine; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Time Factors | 1986 |
Effects of a new dihydropyridine calcium antagonist on vascular smooth muscles, cardiac muscles and [3H]-nitrendipine binding.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Guinea Pigs; Heart; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Rabbits; Rats; Rats, Inbred Strains; Vasodilator Agents | 1986 |
Pharmacokinetics and metabolism of calcium-blocking agents nifedipine, nitrendipine, and nimodipine.
Topics: Biological Availability; Female; Half-Life; Humans; Individuality; Kinetics; Male; Nifedipine; Nimodipine; Nitrendipine | 1986 |
Effects of temperature and allosteric modulators on [3H] nitrendipine binding: methods for detecting potential Ca2+ channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Animals; Benzothiazoles; Binding Sites; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Microsomes; Myocardium; Nifedipine; Nitrendipine; Propylamines; Temperature; Thiazoles; Tiapamil Hydrochloride; Verapamil | 1984 |
Interaction of the calcium channel activating 3H-BAY K 8644 and inhibiting 3H-verapamil with specific receptor sites on cultured beating myocardial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Calcium Channel Blockers; Cells, Cultured; Kinetics; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Receptors, Drug; Verapamil | 1984 |
Acute hemodynamic effects of nitrendipine in chronic congestive heart failure.
Topics: Adult; Aged; Calcium Channel Blockers; Cardiac Output; Chronic Disease; Female; Forearm; Heart Failure; Hemodynamics; Humans; Liver Circulation; Male; Middle Aged; Nifedipine; Nitrendipine; Pulmonary Circulation; Regional Blood Flow; Renal Circulation; Stroke Volume; Vascular Resistance; Vasodilator Agents | 1984 |
Large arteries in hypertension: acute effects of a new calcium entry blocker, nitrendipine.
Topics: Adult; Arteries; Blood Pressure; Calcium Channel Blockers; Female; Forearm; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Regional Blood Flow; Vascular Resistance | 1984 |
Nitrendipine: hemodynamic effects in conscious normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Heart; Hemodynamics; Hypertension; Male; Nifedipine; Nitrendipine; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Time Factors | 1984 |
Nitrendipine reverses vasoconstriction and renal hemodynamic changes in experimental hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Glomerular Filtration Rate; Hypertension; Male; Nifedipine; Nitrendipine; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Renal Circulation; Sodium; Time Factors; Vasoconstriction | 1984 |
Effect of nitrendipine on urine volume, osmolality, and electrolyte excretion in normal, adrenal-enucleate, and mononephrectomized rats.
Topics: Adrenalectomy; Animals; Calcium Channel Blockers; Diuresis; Electrolytes; Female; Glomerular Filtration Rate; Kidney Tubules, Collecting; Nephrectomy; Nephrons; Nifedipine; Nitrendipine; Osmolar Concentration; Potassium; Rats; Rats, Inbred Strains; Sodium | 1984 |
Renal effects of nitrendipine monotherapy in essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Volume; Calcium Channel Blockers; Cardiac Output; Epinephrine; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Nifedipine; Nitrendipine; Norepinephrine; Renal Circulation; Renin; Time Factors | 1984 |
Acute and long-term effects of nitrendipine on resting and exercise hemodynamics in essential hypertension.
Topics: Adult; Atenolol; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Physical Exertion; Time Factors; Vascular Resistance | 1984 |
Efficacy and safety of nitrendipine in patients with severe hypertension: a multiclinic study.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Propranolol; Time Factors | 1984 |
Nitrendipine in hypertension that is difficult to control.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine | 1984 |
Safety aspects of long-term nitrendipine therapy.
Topics: Calcium Channel Blockers; Drug Therapy, Combination; Electrocardiography; Humans; Hydrochlorothiazide; Hypertension, Renal; Male; Middle Aged; Nifedipine; Nitrendipine; Potassium; Time Factors; Uric Acid | 1984 |
Antihypertensive therapy with the long-acting calcium antagonist nitrendipine.
Topics: Adult; Aged; Blood Pressure; Body Weight; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Renin; Verapamil | 1984 |
The calcium channel blocker nitrendipine in single- and multiple-agent antihypertensive regimens: preliminary report of a multicenter study.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Calcium Channel Blockers; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Propranolol; Renin; Sodium; Time Factors | 1984 |
Long-term effectiveness of BAY e 5009-nitrendipine in the treatment of mild and moderate arterial hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Posture | 1984 |
Calcium antagonists for antihypertensive baseline therapy. First International Nitrendipine Symposium. Interlaken, April 13-14, 1984.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Nitrendipine | 1984 |
Place of calcium antagonists in antihypertensive therapy: introduction and round-table discussion.
Topics: Blood Pressure; Calcium Channel Blockers; Diet, Sodium-Restricted; Diuretics; Humans; Hypertension; Nifedipine; Nitrendipine; Renin | 1984 |
Calcium antagonists and excitation of the vascular muscle membrane.
Topics: Animals; Calcium Channel Blockers; Cell Membrane; Female; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1984 |
Some recent pharmacological findings with nitrendipine.
Topics: Acute Kidney Injury; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cattle; Cells, Cultured; Female; Gentamicins; Glycerol; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Norepinephrine; Rabbits; Rats; Rats, Inbred Strains | 1984 |
Antagonism of Ca2+-induced constriction of isolated rabbit ear artery by nitrendipine in high K+- and/or norepinephrine-containing medium.
Topics: Animals; Arteries; Calcium; Calcium Channel Blockers; Ear; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Norepinephrine; Potassium; Rabbits; Vasoconstriction | 1984 |
Mode of antihypertensive action of nitrendipine.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Diet; Dihydralazine; Heart; Hypertension; Hypertension, Malignant; Kidney; Male; Minoxidil; Nifedipine; Nitrendipine; Organ Size; Rats; Rats, Inbred SHR; Sodium Chloride; Vasodilation | 1984 |
Pharmacokinetics of nitrendipine in patients with renal failure: comparison to normal subjects.
Topics: Adult; Aged; Biotransformation; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Creatinine; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Nifedipine; Nitrendipine | 1984 |
Steady-state pharmacokinetics of nitrendipine in hepatic insufficiency.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Chronic Disease; Humans; Kinetics; Liver Diseases; Liver Diseases, Alcoholic; Male; Middle Aged; Nifedipine; Nitrendipine; Pulse | 1984 |
Drug interactions with nitrendipine.
Topics: Adrenergic beta-Antagonists; Adult; Calcium Channel Blockers; Chromatography, Gas; Cimetidine; Digitalis Glycosides; Digoxin; Drug Interactions; Female; Histamine H2 Antagonists; Humans; Kinetics; Male; Nifedipine; Nitrendipine; Ranitidine | 1984 |
Parallel reduction of calcium-influx-dependent vasoconstriction and platelet-free calcium concentration with calcium entry and beta-adrenoceptor blockade.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Blood Platelets; Blood Pressure; Calcium; Calcium Channel Blockers; Cytosol; Dose-Response Relationship, Drug; Epinephrine; Female; Forearm; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Nitroprusside; Norepinephrine; Regional Blood Flow; Renin; Vasoconstriction | 1984 |
Human red blood cells--an ideal model system for the action of calcium agonists and antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Erythrocytes; Humans; Ion Channels; Nicardipine; Nifedipine; Nitrendipine; Pyridines; Stimulation, Chemical; Verapamil | 1984 |
Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.
Topics: Animals; Binding Sites; Cattle; Dihydropyridines; Electrophysiology; Heart Conduction System; Ion Channels; Membrane Potentials; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Purkinje Fibers; Pyridines; Verapamil | 1984 |
The nitrendipine-sensitive Ca2+ channel in chick muscle cells and its appearance during myogenesis in vitro and in vivo.
Topics: Animals; Calcium; Calcium Channels; Carrier Proteins; Cells, Cultured; Chick Embryo; Ion Channels; Muscle Denervation; Muscle Development; Muscles; Nifedipine; Nitrendipine; Receptors, Nicotinic; Sodium Channels | 1984 |
High affinity specific [3H](+)PN 200-110 binding to dihydropyridine receptors associated with calcium channels in rat cerebral cortex and heart.
Topics: Animals; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Ion Channels; Isradipine; Kinetics; Male; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Receptors, Nicotinic | 1984 |
Solubilization and affinity labeling of a dihydropyridine binding site from skeletal muscle: effects of temperature and diltiazem on [3H]dihydropyridine binding to transverse tubules.
Topics: Affinity Labels; Animals; Benzazepines; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Diltiazem; Intracellular Membranes; Kinetics; Microsomes; Microtubules; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rabbits; Receptors, Nicotinic; Temperature | 1984 |
Comparative structure-activity relationships for dihydropyridines as inhibitors of [3H]-nitrendipine binding vs cyclic nucleotide phosphodiesterases.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Binding, Competitive; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Kinetics; Male; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rats; Structure-Activity Relationship | 1984 |
Properties of receptors for the Ca2+-channel blocker verapamil in transverse-tubule membranes of skeletal muscle. Stereospecificity, effect of Ca2+ and other inorganic cations, evidence for two categories of sites and effect of nucleoside triphosphates.
Topics: Animals; Bepridil; Binding, Competitive; Calcium; Calcium Channels; Cations, Divalent; Cations, Monovalent; Diltiazem; Electrochemistry; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Muscles; Nifedipine; Nitrendipine; Nucleotides; Pyrrolidines; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil | 1984 |
Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.
Topics: Animals; Calcium; Calcium Channel Blockers; Dogs; Female; Heart; Ion Channels; Male; Membrane Potentials; Nifedipine; Nitrendipine | 1984 |
Nitrendipine: effects on vascular responses and myocardial binding.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Cats; Dogs; Female; Ion Channels; Male; Microsomes; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Papillary Muscles; Rabbits; Rats | 1984 |
Interaction of phenoxybenzamine with muscarinic receptors and calcium channels.
Topics: Animals; Calcium; Calcium Channel Blockers; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Phenoxybenzamine; Potassium; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tritium | 1984 |
Phenytoin interacts with calcium channels in brain membranes.
Topics: Animals; Brain; Calcium; Carbamazepine; Clonazepam; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1984 |
The cholesterol content of the human erythrocyte influences calcium influx through the channel.
Topics: Calcium; Cholesterol; Erythrocytes; Humans; Ion Channels; Kinetics; Liposomes; Nifedipine; Nitrendipine; Phosphatidylcholines; Time Factors | 1984 |
Characterization of verapamil binding sites in cardiac membrane vesicles.
Topics: Animals; Calcium Channels; Diltiazem; Heart Ventricles; Kinetics; Myocardium; Nifedipine; Nitrendipine; Receptors, Nicotinic; Sarcolemma; Swine; Verapamil | 1984 |
Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Calcium; Calcium Channel Blockers; Cerebral Cortex; Ion Channels; Kinetics; Male; Nifedipine; Nitrendipine; Piperidines; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1983 |
Dopamine antagonist effect of verapamil on isolated perfused rabbit ear artery.
Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Nifedipine; Nitrendipine; Perfusion; Rabbits; Sulpiride; Vasoconstriction; Verapamil | 1983 |
Postjunctional alpha-adrenoceptors in the isolated saphenous vein of the rabbit. Characterization and influence of angiotensin.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Phenoxybenzamine; Rabbits; Receptors, Adrenergic, alpha; Saphenous Vein | 1983 |
B-HT 920 acts as an alpha 1-adrenoceptor agonist in the rabbit aorta under certain in vitro conditions.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Aorta, Thoracic; Azepines; Calcium; Female; In Vitro Techniques; Ion Channels; Male; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Phenylephrine; Rabbits; Reserpine; Yohimbine | 1984 |
Interference of calcium entry blockade in vivo with pressor responses to alpha-adrenergic stimulation: effects of two unrelated blockers on responses to both exogenous and endogenously released norepinephrine.
Topics: Adrenergic alpha-Agonists; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electric Stimulation; Female; Nifedipine; Nitrendipine; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Vasoconstriction; Verapamil; Yohimbine | 1984 |
Comparative actions of dihydropyridine slow channel calcium blocking agents in conscious dogs: systemic and coronary hemodynamics with and without combined beta adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dogs; Female; Heart Rate; Hemodynamics; Hydralazine; Male; Nifedipine; Nisoldipine; Nitrendipine; Propranolol; Vasodilator Agents | 1984 |
Heterogeneity of systemic hemodynamic response to a new calcium entry blocker, nitrendipine.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Hemodynamics; Hypertension; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains | 1982 |
Novel 1,4-dihydropyridine (Bay K 8644) facilitates calcium-dependent [3H]noradrenaline release from PC 12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Calcium; Dose-Response Relationship, Drug; Kinetics; Nifedipine; Nitrendipine; Norepinephrine; Pheochromocytoma; Potassium; Rats | 1984 |
Specific binding of a calcium channel activator, [3H]BAY k 8644, to membranes from cardiac muscle and brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Binding, Competitive; Brain; Calcium; Cell Membrane; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Myocardium; Nifedipine; Nitrendipine; Rabbits | 1984 |
Calcium channel 'agonist' BAY K 8644 inhibits calcium antagonist binding to brain and PC12 cell membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Brain; Calcium; Cell Line; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Pheochromocytoma; Rats; Rats, Inbred Strains | 1984 |
Interactions of maitotoxin with voltage-sensitive calcium channels in cultured neuronal cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Diltiazem; Dose-Response Relationship, Drug; Gallopamil; Ion Channels; Marine Toxins; Neurons; Nifedipine; Nitrendipine; Oxocins; Potassium | 1984 |
Calcium channel activation: a different type of drug action.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Calcium Channel Blockers; Cell Line; Diltiazem; Gallopamil; Glioma; Hybrid Cells; Ion Channels; Kinetics; Mice; Neuroblastoma; Nifedipine; Nitrendipine; Pyridines; Rats | 1984 |
Effects of Bay k 8644, a dihydropyridine analog, on [3H]nitrendipine binding to canine cardiac sarcolemma and the relationship to a positive inotropic effect.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Dogs; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Sarcolemma; Stimulation, Chemical | 1984 |
Correlation of nitrendipine and Bay k 8644 binding to isolated canine heart sarcolemma with their pharmacological effects on the canine heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Dogs; Heart; In Vitro Techniques; Kinetics; Myocardium; Nifedipine; Nitrendipine; Sarcolemma | 1984 |
Inhibition of turkey gizzard myosin light chain kinase activity by BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calmodulin; Enzyme Activation; Felodipine; Gizzard, Avian; In Vitro Techniques; Myosin-Light-Chain Kinase; Nifedipine; Nitrendipine; Protein Kinase Inhibitors; Turkeys | 1984 |
BAY K 8644, a 1,4-dihydropyridine Ca2+ channel activator: dissociation of binding and functional effects in brain synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Brain; Calcium; Calcium Channel Blockers; Cerebral Cortex; Guinea Pigs; Ion Channels; Male; Nifedipine; Nitrendipine; Potassium; Rats; Synaptosomes | 1984 |
Characteristics of the binding of [3H]nitrendipine to rabbit ventricular membranes: modification by other Ca++ channel antagonists and by the Ca++ channel agonist Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Cadmium; Calcium Channel Blockers; Female; In Vitro Techniques; Kinetics; Lanthanum; Myocardium; Nifedipine; Nitrendipine; Rabbits; Stereoisomerism; Tritium | 1984 |
Dihydropyridine calcium agonist and antagonist effects on aldosterone secretion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Dantrolene; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium; Stimulation, Chemical | 1984 |
Effects of dihydropyridine calcium channel modulators in the heart: pharmacological and radioligand binding correlations.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rats; Stimulation, Chemical | 1984 |
Binding of a calcium antagonist, [3H]nitrendipine, to high affinity sites in bovine aortic smooth muscle and canine cardiac membranes.
Topics: Animals; Aorta; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cattle; Dogs; Heart Ventricles; Ion Channels; Membranes; Muscle, Smooth, Vascular; Nifedipine; Nisoldipine; Nitrendipine; Pyridines | 1982 |
[3H]nitrendipine-labeled calcium channels discriminate inorganic calcium agonists and antagonists.
Topics: Animals; Brain; Brain Mapping; Calcium; Cations, Divalent; Guinea Pigs; Ion Channels; Kinetics; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Tissue Distribution | 1982 |
Calcium antagonists High-affinity binding and inhibition of calcium transport in a clonal cell line.
Topics: Adrenal Gland Neoplasms; Animals; Binding, Competitive; Biological Transport, Active; Calcium; Calcium Channel Blockers; Cell Line; Ion Channels; Kinetics; Neoplasms, Experimental; Nifedipine; Nitrendipine; Pheochromocytoma; Pyridines; Rats | 1982 |
Specific binding of [3H]nitrendipine to membranes from coronary arteries and heart in relation to pharmacological effects. Paradoxical stimulation by diltiazem.
Topics: Animals; Benzazepines; Binding Sites; Calcium; Coronary Vessels; Diltiazem; Dogs; Ion Channels; Isomerism; Kinetics; Microsomes; Myocardium; Nifedipine; Nitrendipine; Pyridines; Sarcolemma; Swine | 1982 |
Diltiazem enhancement of [3H]nitrendipine binding to calcium channel associated drug receptor sites in rat brain synaptosomes.
Topics: Allosteric Regulation; Animals; Benzazepines; Brain; Calcium; Diltiazem; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Drug; Synaptosomes | 1982 |
Interaction of verapamil and other calcium channel blockers with alpha 1- and alpha 2-adrenergic receptors.
Topics: Animals; Binding, Competitive; Blood Platelets; Calcium Channel Blockers; Drug Interactions; Humans; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Verapamil | 1983 |
[3H]nitrendipine labelling of the Ca2+ channel in skeletal muscle.
Topics: Animals; Calcium; Calcium Channel Blockers; In Vitro Techniques; Ion Channels; Membranes; Microtubules; Muscles; Nifedipine; Nitrendipine; Pyridines; Rabbits; Subcellular Fractions | 1982 |
A calcium antagonist drug binding site in skeletal muscle sarcoplasmic reticulum: evidence for a calcium channel.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Cinnarizine; Egtazic Acid; Flunarizine; Gallic Acid; Ion Channels; Muscle Contraction; Neuromuscular Junction; Nifedipine; Nitrendipine; Pyridines; Rabbits; Sarcoplasmic Reticulum; Verapamil | 1983 |
Determination of the molecular size of the nitrendipine-sensitive Ca2+ channel by radiation inactivation.
Topics: Animals; Binding Sites; Brain Chemistry; Cats; Dose-Response Relationship, Radiation; Ion Channels; Male; Molecular Weight; Muscles; Nifedipine; Nitrendipine; Pyridines; Rabbits; Rats; Rats, Inbred Strains; Synaptic Membranes | 1983 |
Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells.
Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Cats; Diltiazem; Gallopamil; Heart; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Nifedipine; Nitrendipine; Verapamil | 1983 |
[3H]nitrendipine receptors in skeletal muscle.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Calcium Channels; Cations; Hydrogen-Ion Concentration; Intracellular Membranes; Kinetics; Muscles; Nifedipine; Nitrendipine; Peptide Hydrolases; Rabbits; Rana esculenta; Receptors, Cholinergic; Receptors, Nicotinic; Tissue Distribution | 1983 |
Binding of the calcium channel blocker nitrendipine to its receptor in purified sarcolemma from canine cardiac ventricle.
Topics: Animals; Calcium Channel Blockers; Dogs; Ion Channels; Myocardium; Nifedipine; Nitrendipine; Pyridines; Receptors, Drug; Sarcolemma | 1983 |
Solubilization of the calcium antagonist receptor from rat brain.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Digitonin; Kinetics; Nifedipine; Nitrendipine; Pyridines; Rats; Receptors, Cholinergic; Receptors, Nicotinic; Solubility; Synaptosomes | 1983 |
Molecular properties of the slow inward calcium channel. Molecular weight determinations by radiation inactivation and covalent affinity labeling.
Topics: Affinity Labels; Animals; Calcium; Dihydropyridines; Guinea Pigs; Ion Channels; Methods; Molecular Weight; Muscles; Nifedipine; Nitrendipine; Pyridines | 1983 |
Allosteric modulation by diltiazem and verapamil of [3H]nitrendipine binding to calcium channel sites in rat brain.
Topics: Allosteric Site; Animals; Benzazepines; Brain; Calcium; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Ion Channels; Kinetics; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Synaptosomes; Verapamil | 1983 |
Differential labelling of putative skeletal muscle calcium channels by [3H]-nifedipine, [3H]-nitrendipine, [3H]-nimodipine and [3H]-PN 200 110.
Topics: Animals; Calcium Channel Blockers; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Kinetics; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles | 1983 |
Relationship of binding of a calcium channel blocker to inhibition of contraction in intact cultured embryonic chick ventricular cells.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cells, Cultured; Chick Embryo; Diltiazem; Heart; In Vitro Techniques; Ion Channels; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Tritium; Verapamil | 1983 |
Ontogenic appearance of Ca2+ channels characterized as binding sites for nitrendipine during development of nervous, skeletal and cardiac muscle systems in the rat.
Topics: Aging; Animals; Brain; Calcium; Calcium Channel Blockers; Fetus; Heart; Ion Channels; Kinetics; Muscle Development; Muscles; Myocardium; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains | 1983 |
A simple sensitive radioreceptor assay for calcium antagonist drugs.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cattle; Cell Membrane; Cerebral Cortex; Diltiazem; In Vitro Techniques; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Prenylamine; Radioligand Assay; Receptors, Nicotinic; Verapamil | 1983 |
Effects of nifedipine derivatives on smooth muscle cells and neuromuscular transmission in the rabbit mesenteric artery.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Female; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Rabbits; Synaptic Transmission | 1983 |
Differentiation of receptor sites for [3H]nitrendipine in chick hearts and physiological relation to the slow Ca2+ channel and to excitation-contraction coupling.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Calcium Channels; Chick Embryo; Chickens; Heart; Humans; Hydroxydopamines; Ion Channels; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Oxidopamine; Receptors, Nicotinic; Reserpine | 1984 |
Identification of calcium antagonist receptor binding sites using (3H)nitrendipine in bovine tracheal smooth muscle membranes.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cattle; Cromolyn Sodium; Kinetics; Muscle, Smooth; Nifedipine; Nisoldipine; Nitrendipine; Receptors, Nicotinic; Trachea; Verapamil | 1984 |
Subcellular distribution of [3H]nitrendipine binding in smooth muscle.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Female; Gastric Fundus; Kinetics; Muscle, Smooth; Myometrium; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Subcellular Fractions | 1984 |
Calcium channel blockade: possible explanation for thioridazine's peripheral side effects.
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Ejaculation; Female; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; Propylamines; Rats; Rats, Inbred Strains; Sexual Dysfunction, Physiological; Thioridazine; Tiapamil Hydrochloride; Vas Deferens; Verapamil | 1984 |
Enhancement of calcium influx in human platelets by CGP 28392, a novel dihydropyridine.
Topics: Animals; Blood Platelets; Calcium; Calcium Channel Blockers; Cell Membrane; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Ion Channels; Myocardium; Nifedipine; Nitrendipine; Pyridines | 1984 |
Ontogeny of calcium antagonist binding sites in chick brain and heart.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels; Chick Embryo; Chickens; Heart; Heart Ventricles; Kinetics; Myocardium; Nifedipine; Nitrendipine; Receptors, Nicotinic | 1984 |
Tityus gamma toxin, a high affinity effector of the Na+ channel in muscle, with a selectivity for channels in the surface membrane.
Topics: Animals; Cell Membrane; Electric Conductivity; Ion Channels; Muscle Contraction; Muscles; Nifedipine; Nitrendipine; Rana esculenta; Scorpion Venoms; Sodium | 1984 |
Interaction of calcium channel blockers with non-neuronal benzodiazepine binding sites.
Topics: Animals; Benzodiazepines; Brain; Calcium Channel Blockers; Kidney; Kinetics; Male; Myocardium; Nifedipine; Nitrendipine; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship | 1984 |
Stimulation of Na+,K+-ATPase of isolated smooth muscle membranes by the Ca2+ channel inhibitors, nimodipine and nitrendipine.
Topics: Animals; Brain; Guinea Pigs; Male; Membranes; Muscle, Smooth; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Ouabain; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1984 |
Inhibition by suloctidil of [3H] nitrendipine binding to cerebral cortex membranes.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Cell Membrane; Cerebral Cortex; Guinea Pigs; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Propanolamines; Structure-Activity Relationship; Suloctidil; Tritium | 1984 |
Direct photoaffinity labeling of the high affinity nitrendipine-binding site in subcellular membrane fractions isolated from canine myocardium.
Topics: Affinity Labels; Animals; Calcium Channel Blockers; Calcium Channels; Dogs; Intracellular Membranes; Light; Myocardium; Nifedipine; Nitrendipine; Phenylmethylsulfonyl Fluoride; Receptors, Nicotinic; Sarcolemma; Sarcoplasmic Reticulum; Sulfones; Ultraviolet Rays; Verapamil | 1984 |
Chemical and pharmacological approaches to the definition and quantitation of calcium channels.
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dogs; Guinea Pigs; Ion Channels; Microsomes; Muscle, Smooth; Muscles; Myocardium; Neurons; Nifedipine; Nitrendipine; Receptors, Nicotinic; Verapamil | 1983 |
Diltiazem-like effect of thioridazine on the dihydropyridine binding site of the calcium channel of rat myocardial membranes.
Topics: Animals; Benzazepines; Binding, Competitive; Calcium; Calcium Channels; Cell Membrane; Diltiazem; In Vitro Techniques; Ion Channels; Male; Myocardium; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Thioridazine | 1984 |
Effect of some smooth muscle relaxant drugs on calcium-related phenomena.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Calcium; Calmodulin; Cyclic Nucleotide Phosphodiesterases, Type 1; Female; Humans; In Vitro Techniques; Myometrium; Nifedipine; Nitrendipine; Parasympatholytics; Spectrometry, Fluorescence | 1984 |
Comparative changes of levels of nitrendipine Ca2+ channels, of tetrodotoxin-sensitive Na+ channels and of ouabain-sensitive (Na+ + K+)-ATPase following denervation of rat and chick skeletal muscle.
Topics: Animals; Calcium; Chickens; Ion Channels; Kinetics; Male; Muscle Denervation; Muscles; Nifedipine; Nitrendipine; Ouabain; Rats; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin | 1984 |
Nitrendipine and isoproterenol induce phosphorylation of a 42,000 dalton protein that co-migrates with the affinity labeled calcium channel regulatory subunit.
Topics: Affinity Labels; Animals; Cell Membrane; Dogs; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Ion Channels; Isoproterenol; Membrane Proteins; Myocardium; Nifedipine; Nitrendipine; Phosphorylation | 1984 |
Altered pressor responses in long-term nitrendipine treatment.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Calcium; Creatinine; Double-Blind Method; Heart Rate; Humans; Hypertension; Infusions, Parenteral; Male; Middle Aged; Nifedipine; Nitrendipine; Norepinephrine; Potassium; Random Allocation; Renin; Sodium | 1984 |
Tissue heterogeneity of calcium channel antagonist binding sites labeled by [3H]nitrendipine.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cerebral Cortex; Edetic Acid; Guinea Pigs; Ileum; Male; Muscles; Myocardium; Nifedipine; Nitrendipine; Tissue Distribution | 1984 |
Role of calcium in arachidonic acid-induced contractions of guinea pig airways.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Channel Blockers; Edetic Acid; Gallic Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Lanthanum; Lung; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; SRS-A; Trachea; Verapamil | 1984 |
Role of calcium in gamma interferon induction: inhibition by calcium entry blockers.
Topics: Calcium; Calcium Channel Blockers; Cells, Cultured; Humans; Interferon-gamma; Kinetics; Lymphocyte Activation; Lymphocytes; Nifedipine; Nitrendipine; Procaine | 1984 |
Effects of metal cations and calmodulin antagonists on [3H] nitrendipine binding in smooth and cardiac muscle.
Topics: Animals; Aorta; Calmodulin; Cations, Divalent; Cattle; Edetic Acid; Guinea Pigs; Ileum; Kinetics; Microsomes; Muscle, Smooth; Myocardium; Nifedipine; Nitrendipine; Rabbits | 1984 |
[3H]nitrendipine binding in the guinea pig left ventricle: effects of calcium and lanthanum.
Topics: Animals; Calcium; Calcium Channel Blockers; Edetic Acid; Female; Guinea Pigs; In Vitro Techniques; Lanthanum; Male; Myocardium; Nifedipine; Nitrendipine; Tritium | 1984 |
Blockers of calcium permeability inhibit neurite extension and formation of neuromuscular synapses in cell culture.
Topics: Age Factors; Animals; Cadmium; Calcium Channel Blockers; Chick Embryo; Cobalt; Gallopamil; Lanthanum; Manganese; Neuromuscular Junction; Nifedipine; Nitrendipine; Retina; Verapamil | 1984 |
Differential influence of the calcium antagonist nitrendipine and the vasodilator hydralazine on normal and elevated blood pressure.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Heart Rate; Hydralazine; Hypertension; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains | 1984 |
[3H]nitrendipine binding to adrenal capsular membranes.
Topics: Adrenal Medulla; Aldosterone; Animals; Binding Sites; Binding, Competitive; Diltiazem; Kinetics; Membranes; Nifedipine; Nitrendipine; Rats; Verapamil | 1984 |
Hoe 263, a new substance with calcium channel antagonistic activity.
Topics: Animals; Benzhydryl Compounds; Calcium Channel Blockers; Calcium Radioisotopes; Cymarine; Dogs; Guinea Pigs; In Vitro Techniques; Membranes; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Neuromuscular Depolarizing Agents; Nifedipine; Nitrendipine; Papillary Muscles; Potassium; Prenylamine; Pulmonary Artery | 1984 |
Comparison of high affinity binding of calcium channel blocking drugs to vascular smooth muscle and cardiac sarcolemmal membranes.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Cattle; Dogs; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; Myocardium; Nifedipine; Nitrendipine; Sarcolemma; Stereoisomerism; Structure-Activity Relationship | 1984 |
Effects of felodipine, nitrendipine and W-7 on arterial myosin phosphorylation, actin-myosin interactions and contraction.
Topics: Actins; Actomyosin; Animals; Calmodulin; Cattle; Contractile Proteins; Felodipine; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardium; Myosins; Nifedipine; Nitrendipine; Phosphorylation; Protein Binding; Rabbits; Sulfonamides; Vasoconstriction | 1984 |
Specific high affinity binding of the calcium channel antagonist, [3H]nitrendipine, to rat liver microsomes.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Gallopamil; In Vitro Techniques; Lanthanum; Male; Microsomes, Liver; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Tritium | 1984 |
Diazepam-stimulated increases in the synaptosomal uptake of 45Ca2+: reversal by dihydropyridine calcium channel antagonists.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Chloride; Calcium Radioisotopes; Cerebral Cortex; Diazepam; Dihydropyridines; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Synaptosomes | 1984 |
Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects.
Topics: Animals; Antidiarrheals; Calcium; Calcium Channel Blockers; Guinea Pigs; Ileum; In Vitro Techniques; Intestinal Mucosa; Loperamide; Male; Muscle Contraction; Nifedipine; Nitrendipine; Piperidines; Tritium | 1984 |
TTX displacement of [H3]-nitrendipine binding in developing spinal cord neurons.
Topics: Animals; Binding, Competitive; Cells, Cultured; Female; Mice; Neurons; Nifedipine; Nitrendipine; Pregnancy; Spinal Cord; Tetrodotoxin; Time Factors | 1984 |
A low dose of a calcium antagonist (nitrendipine) ameliorates cardiac and renal lesions induced by DOC in the rat.
Topics: Animals; Blood Pressure; Body Weight; Calcium; Desoxycorticosterone; Drug Interactions; Female; Heart; Kidney; Myocardium; Nifedipine; Nitrendipine; Rats | 1984 |
In vivo chronic lead exposure alters [3H]nitrendipine binding in rat striatum.
Topics: Animals; Corpus Striatum; Female; Lead Poisoning; Nifedipine; Nitrendipine; Pregnancy; Rats; Rats, Inbred Strains; Synaptic Membranes | 1984 |
Activation mechanisms of human renal artery: effects of KCl, norepinephrine and nitrendipine upon tension development and 45Ca influx.
Topics: Biological Transport; Calcium; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Depolarizing Agents; Nifedipine; Nitrendipine; Norepinephrine; Potassium Chloride; Renal Artery | 1984 |
Interactions between Ca2+-antagonist binding sites in rat adenohypophysis: dependence on estrous cycle.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium; Estrus; Female; Gallopamil; Kinetics; Male; Nifedipine; Nitrendipine; Pituitary Gland, Anterior; Pregnancy; Rats | 1984 |
Inhibition of turkey gizzard myosin light chain. Kinase activity by dihydropyridine calcium antagonists.
Topics: Animals; Calcium; Calcium Channel Blockers; Felodipine; Gizzard, Avian; Kinetics; Myosin-Light-Chain Kinase; Myosins; Nifedipine; Nitrendipine; Phosphorylation; Protein Kinase Inhibitors; Trypsin; Turkeys | 1984 |
A unitary mechanism of calcium antagonist drug action.
Topics: Binding, Competitive; Calcium Channel Blockers; Ileum; Kinetics; Nifedipine; Nitrendipine | 1983 |
Mode of action of calcium antagonists which alter anthracycline resistance.
Topics: Animals; Antibiotics, Antineoplastic; Biological Transport; Calcium Channel Blockers; Cell Line; Daunorubicin; Doxorubicin; Drug Resistance; Leukemia P388; Mice; Naphthacenes; Nifedipine; Nitrendipine; Verapamil | 1984 |
Uptake of calcium antagonistic drugs into muscles as related to their lipid solubilities.
Topics: Animals; Bepridil; Calcium Channel Blockers; Lipid Metabolism; Muscles; Nifedipine; Nitrendipine; Pyrrolidines; Rana pipiens; Rats; Sarcoplasmic Reticulum; Solubility; Verapamil | 1984 |
Effects of two new Ca-entry blockers bepridil and nitrendipine on isolated vessels.
Topics: Adult; Aged; Animals; Aorta, Thoracic; Bepridil; Calcium Channel Blockers; Female; Femoral Vein; Humans; In Vitro Techniques; Leg; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Norepinephrine; Portal Vein; Potassium; Pyrrolidines; Rats; Veins | 1984 |
Non-invasive, kinetic measurements of [3H]nitrendipine binding to isolated rat myocytes by condensed phase radioluminescence.
Topics: Animals; Cell Membrane; Cells, Cultured; Dihydroalprenolol; Fluorometry; Kinetics; Luminescence; Myocardium; Nifedipine; Nitrendipine; Rats; Tritium | 1983 |
45Ca2+ uptake into rat whole brain synaptosomes unaltered by dihydropyridine calcium antagonists.
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Male; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes | 1983 |
The ontogeny of specific binding sites for the calcium channel antagonist, nitrendipine, in mouse heart and brain.
Topics: Animals; Animals, Newborn; Binding Sites; Brain; Calcium Channel Blockers; Male; Mice; Mice, Inbred Strains; Myocardium; Nifedipine; Nitrendipine; Time Factors | 1983 |
The measurement of free nitrendipine in human serum by an equilibrium dialysis - radioreceptor assay.
Topics: Animals; Calcium Channel Blockers; Dialysis; Humans; Nifedipine; Nitrendipine; Protein Binding; Radioligand Assay; Rats; Rats, Inbred Strains | 1983 |
Diltiazem and nitrendipine suppress hypoxic contracture in quiescent ventricular myocardium.
Topics: Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Hypoxia; In Vitro Techniques; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Rabbits | 1983 |
The effect of a calcium-channel blocking agent on intraocular pressure.
Topics: Adult; Calcium Channel Blockers; Female; Humans; Intraocular Pressure; Male; Middle Aged; Nifedipine; Nitrendipine | 1983 |
Nitrendipine: identification and synthesis of main metabolites.
Topics: Animals; Bile; Biotransformation; Chemical Phenomena; Chemistry; Feces; Kinetics; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains | 1983 |
Salutary effects of nitrendipine, a new calcium entry blocker, in hemorrhagic shock.
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Cathepsin D; Cathepsins; Cats; Disease Models, Animal; Heart Rate; Male; Mesenteric Arteries; Myocardial Depressant Factor; Nifedipine; Nitrendipine; Peptides; Regional Blood Flow; Shock, Hemorrhagic | 1984 |
Reduced cardiac mass by nitrendipine is dissociated from systemic or regional haemodynamic changes in rats.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Body Weight; Calcium Channel Blockers; Heart; Hemodynamics; Male; Nifedipine; Nitrendipine; Organ Size; Rats; Rats, Inbred Strains; Vascular Resistance | 1984 |
Temperature-dependent modulation of [3H]nitrendipine binding by the calcium channel antagonists verapamil and diltiazem in rat brain synaptosomes.
Topics: Animals; Benzazepines; Binding Sites; Brain; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Synaptosomes; Temperature; Tritium; Verapamil | 1984 |
High affinity binding sites for [3H]-nitrendipine in rabbit uterine smooth muscle.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Cell Membrane; Cinnarizine; Depression, Chemical; Dose-Response Relationship, Drug; Female; Flunarizine; Muscle, Smooth; Nifedipine; Nitrendipine; Rabbits; Uterus; Verapamil | 1984 |
Control of spontaneous and deoxycorticosterone-salt hypertension and polyuria by nitrendipine pellets.
Topics: Animals; Antihypertensive Agents; Body Weight; Desoxycorticosterone; Female; Hypertension; Nifedipine; Nitrendipine; Organ Size; Polyuria; Potassium; Rats; Rats, Inbred Strains; Sodium; Time Factors | 1984 |
Systemic and regional hemodynamics in normotensive and spontaneously hypertensive rats after slow-channel calcium blocker nitrendipine.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Heart Rate; Hemodynamics; Hypertension; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Regional Blood Flow; Time Factors; Vascular Resistance | 1984 |
Clinical and systemic hemodynamic effects of nitrendipine.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Volume; Cardiac Output; Dose-Response Relationship, Drug; Drug Evaluation; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Renin-Angiotensin System; Tachycardia | 1984 |
Nitrendipine prolongs rat parturition: no changes occur in progesterone withdrawal.
Topics: Animals; Calcium; Female; Labor, Obstetric; Nifedipine; Nitrendipine; Pregnancy; Progesterone; Rats; Time Factors; Uterine Contraction | 1984 |
Comparative actions of dihydropyridine slow channel calcium blocking agents in conscious dogs: alterations in baroreflex sensitivity.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Female; Heart Rate; Hydralazine; Male; Nifedipine; Nisoldipine; Nitrendipine; Pressoreceptors | 1984 |
Nitrendipine and other calcium entry blockers (calcium antagonists) in hypertension.
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Dogs; Gallopamil; Heart; Hypertension; Male; Nifedipine; Nitrendipine; Organ Size; Potassium; Pyridines; Rats; Rats, Inbred Strains; Vasoconstriction | 1983 |
Immediate hemodynamic effects of a new calcium-channel blocking agent (nitrendipine) in essential hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Posture; Pyridines; Stroke Volume | 1983 |
Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cinnarizine; Cobalt; Dose-Response Relationship, Drug; Drug Synergism; Flunarizine; Guinea Pigs; Ileum; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyridines; Structure-Activity Relationship; Verapamil | 1983 |
In vivo identification of calcium antagonist binding sites using [3H]nitrendipine.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains | 1983 |
Binding of [3H]nitrendipine to heart and brain membranes from normotensive and spontaneously hypertensive rats.
Topics: Animals; Binding Sites; Brain; Hypertension; Kinetics; Male; Membranes; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains | 1983 |
Specific binding of the calcium antagonist [3H]nitrendipine to subcellular fractions isolated from canine myocardium. Evidence for high affinity binding to ryanodine-sensitive sarcoplasmic reticulum vesicles.
Topics: Animals; Binding Sites; Dogs; Myocardium; Nifedipine; Nitrendipine; Pyridines; Subcellular Fractions | 1983 |
Uptake of [3H]nitrendipine into cardiac and smooth muscles.
Topics: Animals; Cats; Chick Embryo; Ileum; Kinetics; Muscle, Smooth; Myocardium; Nifedipine; Nitrendipine; Pyridines; Verapamil | 1983 |
Autoradiographic localization of a calcium channel antagonist, [3H]nitrendipine, binding site in rat brain.
Topics: Animals; Autoradiography; Binding Sites; Brain; Calcium Channel Blockers; Hippocampus; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Verapamil | 1983 |
Prevention of DOCA-salt hypertension with the calcium blocker nitrendipine.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Female; Hypertension; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Sodium Chloride | 1983 |
Radioreceptor and high-performance liquid chromatographic assays for the calcium channel antagonist nitrendipine in serum.
Topics: Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; In Vitro Techniques; Male; Membranes; Myocardium; Nifedipine; Nitrendipine; Pyridines; Radioligand Assay; Rats; Rats, Inbred Strains | 1983 |
Calcium antagonist receptor binding sites labeled with [3H]nitrendipine.
Topics: Animals; Binding Sites; Brain; Calcium Channel Blockers; In Vitro Techniques; Kinetics; Membranes; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rats | 1982 |
The interaction of [3H]nitrendipine with receptors for calcium antagonists in the cerebral cortex and heart of rats.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Chloride; Cerebral Cortex; Diltiazem; Gallopamil; Kinetics; Lanthanum; Male; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Drug; Verapamil | 1982 |
High affinity binding of a calcium channel antagonist to smooth and cardiac muscle.
Topics: Animals; Calcium Channel Blockers; Guinea Pigs; Heart Ventricles; Ileum; Male; Microsomes; Muscle, Smooth; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Stereoisomerism | 1982 |
The binding of [3H]nitrendipine to receptors for calcium channel antagonists in the heart, cerebral cortex, and ileum of rats.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Cerebral Cortex; Heart; Ileum; In Vitro Techniques; Kinetics; Male; Muscle, Smooth; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Verapamil | 1982 |
Autoradiographic visualization of [3H]nitrendipine binding sites in rat brain: localization to synaptic zones.
Topics: Animals; Autoradiography; Binding Sites; Brain; Calcium Channel Blockers; Nifedipine; Nitrendipine; Pyridines; Rats; Synapses | 1982 |
Binding of [3H]nimodipine to cardiac and smooth muscle membranes.
Topics: Animals; Calcium Channel Blockers; Kinetics; Male; Membranes; Microsomes; Muscle, Smooth; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rats | 1982 |
Certain calcium antagonists are potent displacers of [3H]phencyclidine (PCP) binding in rat brain.
Topics: Animals; Binding, Competitive; Brain; Calcium Channel Blockers; Gallopamil; In Vitro Techniques; Nifedipine; Nitrendipine; Olfactory Bulb; Phencyclidine; Rats; Verapamil | 1982 |
Nitrendipine increases sodium excretion in acutely saline-loaded rats.
Topics: Animals; Calcium Channel Blockers; Diuresis; Female; Hypertension; Natriuresis; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Vasodilator Agents | 1982 |
Specific calcium antagonist binding sites in brain.
Topics: Animals; Binding Sites; Brain; Calcium; Cell Membrane; Hot Temperature; Male; Membrane Proteins; Nerve Tissue Proteins; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Trypsin; Verapamil | 1982 |
Calcium-channel antagonist binding to isolated vascular smooth muscle membranes.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Cell Membrane; Dogs; In Vitro Techniques; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium Chloride; Rats | 1982 |
Pharmacological studies of the antihypertensive effect of nitrendipine.
Topics: Animals; Antihypertensive Agents; Blood Flow Velocity; Calcium Channel Blockers; Cardiac Output; Dogs; Drug Tolerance; Heart Rate; Hypertension, Renal; Nifedipine; Nitrendipine; Pyridines; Rats; Vascular Resistance | 1981 |
Effect of a new calcium antagonist, nitrendipine, on blood pressure and heart rate of conscious, unrestrained dogs.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hydralazine; Hypertension, Renal; Male; Nifedipine; Nitrendipine; Pyridines | 1981 |
[3H]-Nitrendipine, a potent calcium antagonist, binds with high affinity to cardiac membranes.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Cell Membrane; Female; Guinea Pigs; Male; Myocardium; Nifedipine; Nitrendipine; Pyridines; Radioligand Assay; Tritium | 1981 |
[3H]-Nimodipine and [3H]-nitrendipine as tools to directly identify the sites of action of 1,4-dihydropyridine calcium antagonists in guinea-pig tissues. Tissue-specific effects of anions and ionic strength.
Topics: Animals; Anions; Binding Sites; Binding, Competitive; Brain; Calcium Channel Blockers; Female; Guinea Pigs; Kidney; Kinetics; Lung; Male; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Organ Specificity; Osmolar Concentration; Pyridines | 1982 |
Leukotriene C4-stimulated contractions in bullfrog lung are affected by cold acclimation and calcium antagonists.
Topics: Acclimatization; Animals; Caffeine; Calcium Channel Blockers; Calcium-Transporting ATPases; Cold Temperature; Contracture; Egtazic Acid; Eicosapentaenoic Acid; Female; Hot Temperature; Leukotriene C4; Lung; Male; Nicardipine; Nifedipine; Nitrendipine; Rana catesbeiana; SRS-A; Terpenes; Thapsigargin; Verapamil | 1995 |
Effects of nifedipine and Bay K 8644 on myotropic responses in aortic rings of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Kinetics; Muscle Contraction; Nifedipine; Nitrendipine; Phenylephrine; Potassium Chloride; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tritium | 1995 |
The dihydropyridine nitrendipine inhibits [3H]MK 801 binding to mouse brain sections.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Autoradiography; Binding, Competitive; Brain; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; N-Methylaspartate; Nifedipine; Nimodipine; Nitrendipine; Software; Verapamil | 1994 |
Calcium antagonist radioprotectors do not reduce radiotherapeutic efficacy in three human tumor xenografts.
Topics: Adenocarcinoma; Animals; Calcium Channel Blockers; Colonic Neoplasms; Diltiazem; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Nifedipine; Nimodipine; Nitrendipine; Radiation-Protective Agents; Radiotherapy Dosage; Sarcoma, Ewing; Transplantation, Heterologous; Whole-Body Irradiation | 1995 |
Changes in extracellular matrix macromolecules in human gingiva after treatment with drugs inducing gingival overgrowth.
Topics: Collagen; Cyclosporine; Elastic Tissue; Elastin; Extracellular Matrix; Extracellular Matrix Proteins; Female; Fibroblasts; Fibronectins; Gingival Hyperplasia; Humans; Hydantoins; Male; Microscopy, Video; Nifedipine; Nitrendipine; Signal Processing, Computer-Assisted; Statistics, Nonparametric | 1995 |
Signal transduction and Ca2+ uptake activated by endothelins in rat brain endothelial cells.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Imidazoles; Inositol 1,4,5-Trisphosphate; Microcirculation; Nifedipine; Nitrendipine; Peptides, Cyclic; Rats; Ryanodine; Signal Transduction | 1994 |
[Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats].
Topics: Animals; Arginine; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Nifedipine; Nitrendipine; Rats; Rats, Sprague-Dawley | 1994 |
[Edema-inducing properties of lacidipine, nitrendipine and nifedipine in the spontaneously hypertensive rat].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Edema; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR; Serum Albumin | 1994 |
Several types of Ca2+ channels mediate glutamatergic synaptic responses to activation of single Thy-1-immunolabeled rat retinal ganglion neurons.
Topics: Animals; Bicuculline; Calcium Channels; Cells, Cultured; gamma-Aminobutyric Acid; Glutamic Acid; Nifedipine; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Quinoxalines; Rats; Retinal Ganglion Cells; Spider Venoms; Synaptic Transmission; Thy-1 Antigens | 1995 |
Experimental vasoprotection by calcium antagonists against calcium-mediated arteriosclerotic alterations.
Topics: Adult; Aged; Aged, 80 and over; Animals; Arteriosclerosis; Calcium; Calcium Channel Blockers; Cells, Cultured; Cholecalciferol; Cholesterol; Coronary Vessels; Diltiazem; Disease Models, Animal; Humans; Hypertension; Middle Aged; Muscle, Smooth, Vascular; Nicotine; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Risk Factors; Verapamil | 1994 |
Effect of activation on adhesion of flowing neutrophils to cultured endothelium: time course and inhibition by a calcium channel blocker (nitrendipine).
Topics: Adult; Antigens, CD; CD18 Antigens; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nifedipine; Nitrendipine | 1993 |
Functional interaction between local anaesthetics and calcium antagonists in guineapig myocardium: 1. Cardiodepressant effects in isolated organs.
Topics: Anesthetics, Local; Animals; Benzocaine; Bupivacaine; Calcium Channel Blockers; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Myocardial Contraction; Nifedipine; Nitrendipine | 1994 |
Cumulative side effects of cyclosporine and Ca antagonists: hypergalactinemia, mastadenoma, and gynecomastia.
Topics: Adenoma; Adult; Aged; Breast Neoplasms, Male; Calcium Channel Blockers; Cyclosporine; Diltiazem; Drug Synergism; Female; Galactorrhea; Gynecomastia; Humans; Kidney Transplantation; Male; Middle Aged; Nifedipine; Nitrendipine | 1994 |
Blockers of Ca2+ channels in the plasmalemma of perfused Characeae cells.
Topics: Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Chlorophyta; Dihydropyridines; Membrane Potentials; Nifedipine; Nitrendipine; Perfusion; Pyridines | 1994 |
Effects of calcium- and ETA-receptor antagonists on endothelin-induced vasoconstriction and levels of endothelin in the human internal mammary artery.
Topics: Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Humans; In Vitro Techniques; Isradipine; Mammary Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nisoldipine; Nitrendipine; Peptides, Cyclic; Radioimmunoassay; Vasoconstriction | 1994 |
Modification of effects of chronic electroconvulsive shock by voltage-dependent Ca2+ channel blockade with nifedipine.
Topics: Animals; Apomorphine; Behavior, Animal; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Electroshock; Hippocampus; Hyperalgesia; Male; Membranes; Motor Activity; Nifedipine; Nitrendipine; Rats; Rats, Wistar; Seizures; Up-Regulation; Weight Gain | 1994 |
Activin A increases intracellular free calcium concentrations in rat pancreatic islets.
Topics: Activins; Animals; Calcium; Carbachol; Cyclic AMP; Diazoxide; Inhibins; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nifedipine; Nitrendipine; Rats; Rats, Wistar; Verapamil | 1993 |
Ca2+ channel blocking activity of lacidipine and amlodipine in A7r5 vascular smooth muscle cells.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cytosol; Dihydropyridines; Female; Fura-2; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium Chloride; Pregnancy; Rats; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1993 |
Radioprotective effects of calcium antagonists used alone or with other types of radioprotectors.
Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Diltiazem; Dimethyl Sulfoxide; Drug Combinations; Female; Flunarizine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Radiation-Protective Agents; Verapamil; Zinc | 1993 |
Actions of 1,4-dihydropyridines in isolated mesenteric vascular beds.
Topics: Animals; Arginine; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Arteries; Nifedipine; Nitrendipine; Nitric Oxide; Nitroarginine; Vasodilation | 1995 |
Differences between haloperidol- and pimozide-induced withdrawal syndrome: a role for Ca2+ channels.
Topics: Animals; Antipsychotic Agents; Apomorphine; Calcium Channels; Haloperidol; Male; Motor Activity; Nifedipine; Nitrendipine; Pimozide; Rats; Rats, Wistar; Receptors, Dopamine D1; Substance Withdrawal Syndrome | 1995 |
Modification of adrenergic reactivity in rat tail artery by dietary lipids and calcium channel antagonists.
Topics: Animals; Arteries; Body Weight; Calcium Channel Blockers; Diet, Atherogenic; Dietary Fats; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nimodipine; Nitrendipine; Norepinephrine; Rats; Rats, Wistar; Regional Blood Flow; Sympathetic Nervous System; Sympathomimetics; Tail | 1996 |
Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Diltiazem; Felodipine; Fumarates; Heart; Iron; Lipid Peroxidation; Male; Myocardium; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Verapamil | 1996 |
L-type calcium channels: binding domains for dihydropyridines and benzothiazepines are located in close proximity to each other.
Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Fluorescent Dyes; Isomerism; Isradipine; Kinetics; Nicotinic Acids; Nifedipine; Nitrendipine; Oxadiazoles; Rabbits | 1997 |
Vasodilation profile of CD-832, a novel dihydropyridine derivative in rabbit aorta.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Calcium Channel Blockers; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Niacinamide; Nicorandil; Nifedipine; Nitrendipine; Nitroglycerin; Norepinephrine; Potassium Chloride; Rabbits; Vasodilation; Vasodilator Agents | 1997 |
Effects of intracavernous calcium channel blockers in dogs.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Heart Rate; Instillation, Drug; Male; Nifedipine; Nitrendipine; Penile Erection; Pressure; Vasodilator Agents; Verapamil | 1997 |
Acetylcholine triggers L-glutamate exocytosis via nicotinic receptors and inhibits melatonin synthesis in rat pinealocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Arylamine N-Acetyltransferase; Atropine; Bungarotoxins; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cells, Cultured; Diltiazem; Exocytosis; Glutamic Acid; Melatonin; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nifedipine; Nitrendipine; Oxotremorine; Parasympathetic Nervous System; Pineal Gland; Rats; Rats, Wistar; Receptors, Nicotinic; Scopolamine; Synaptic Vesicles; Tubocurarine | 1998 |
Effects of various Ca2+ channel antagonists on morphine analgesia, tolerance and dependence, and on blood pressure in the rat.
Topics: Analgesics, Opioid; Animals; Binding Sites; Blood Pressure; Calcium Channel Blockers; Cerebral Cortex; Drug Interactions; Drug Tolerance; Male; Morphine; Nifedipine; Nimodipine; Nitrendipine; Rats; Rats, Wistar; Substance-Related Disorders; Tritium; Verapamil | 1998 |
L-type Ca2+ channels in inspiratory neurones of mice and their modulation by hypoxia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aerobiosis; Ammonium Chloride; Animals; Animals, Newborn; Barium; Calcium Channels; Calcium Channels, L-Type; Cell Hypoxia; In Vitro Techniques; Inhalation; Ion Channel Gating; Medulla Oblongata; Membrane Potentials; Mice; Neurons; Nifedipine; Nitrendipine; Patch-Clamp Techniques; Probability; Quaternary Ammonium Compounds | 1998 |
A calcium agonist, Bay k 8644, suppresses the embryotoxic effects induced by dihydropyridines calcium channel blockers in cultured rat embryos.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Culture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Male; Nicardipine; Nifedipine; Nitrendipine; Rats; Rats, Sprague-Dawley | 1998 |
Calcium channels coupled to neurotransmitter release at neonatal rat neuromuscular junctions.
Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Diaphragm; Embryo, Mammalian; Evoked Potentials; Motor Endplate; Muscle, Skeletal; Neuromuscular Junction; Neurotransmitter Agents; Nifedipine; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Phrenic Nerve; Rats; Rats, Wistar; Spider Venoms; Synaptic Transmission | 1999 |
Intracellular Ca2+ concentrations in cultured chicken photoreceptor cells: sustained elevation in depolarized cells and the role of dihydropyridine-sensitive Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chick Embryo; Membrane Potentials; Nifedipine; Nitrendipine; Photoreceptor Cells, Vertebrate; Time Factors | 1999 |
Free radicals in irradiated drugs: an EPR study.
Topics: Calcium Channel Blockers; Dose-Response Relationship, Radiation; Electron Spin Resonance Spectroscopy; Felodipine; Free Radicals; Gamma Rays; Nifedipine; Nimodipine; Nitrendipine | 1999 |
Calcium channel activation and self-biting in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior | 1999 |
Functional alteration of dihydropyridine-sensitive Ca(2+) channels in the adrenal glomerulosa of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Radioisotopes; Cell Membrane; Female; Nifedipine; Nitrendipine; Potassium Chloride; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tritium; Verapamil; Zona Glomerulosa | 2000 |
Dihydropyridine-induced Ca2+ release from ryanodine-sensitive Ca2+ pools in human skeletal muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Humans; Muscle, Skeletal; Nifedipine; Nitrendipine; PC12 Cells; Protein Conformation; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel | 2000 |
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR.
Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil | 2000 |
[Hypertensive crisis, hypertensive emergency. Nitrate spray and ambulance--this can also be wrong].
Topics: Administration, Oral; Aerosols; Ambulances; Emergencies; Female; Humans; Hypertension, Malignant; Nifedipine; Nitrendipine; Nitroglycerin; Pregnancy; Risk Factors | 2001 |
Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Chloride Channels; Dihydropyridines; Drug Interactions; Glycine; Neural Inhibition; Neurons; Nicardipine; Nifedipine; Nitrendipine; Rats; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Synaptic Transmission; Verapamil | 2001 |
[When hypertension becomes an emergency case: lower the blood pressure, but slowly!].
Topics: Administration, Oral; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Diagnosis, Differential; Dihydralazine; Emergencies; Hospitalization; Humans; Hypertension; Hypertension, Malignant; Injections, Intravenous; Nifedipine; Nitrendipine; Nitroglycerin; Piperazines; Time Factors; Vasodilator Agents | 2003 |
Ca2+ influx does not trigger glucose-induced traffic of the insulin granules and alteration of their distribution.
Topics: Calcium; Calcium Signaling; Cell Line; Cytoplasm; Diazoxide; Dose-Response Relationship, Drug; Down-Regulation; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Myosin Light Chains; Nifedipine; Nitrendipine; Phosphorylation; Tetradecanoylphorbol Acetate; Time Factors | 2003 |
Analysis of phenomena involved in the apical growth of Phycomyces blakesleeanus.
Topics: beta-Fructofuranosidase; Calcimycin; Calcium Channel Blockers; Carbohydrate Metabolism; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chitin; Hyphae; Ionophores; Nifedipine; Nigericin; Nitrendipine; Phycomyces; Protein Transport; Ruthenium Red; Secretory Vesicles; Valinomycin | 2003 |
Oxidation of Hantzsch 1,4-dihydropyridines of pharmacological significance by electrogenerated superoxide.
Topics: Calcium Channel Blockers; Felodipine; Nifedipine; Nimodipine; Nitrendipine; Superoxides | 2004 |
Paradoxical nifedipine facilitation of 45Ca uptake into rat hippocampal synaptosomes.
Topics: Anesthetics, Local; Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Central Nervous System; Dose-Response Relationship, Drug; Female; Hippocampus; Male; Nifedipine; Nitrendipine; Rats; Synaptosomes; Tetrodotoxin | 2006 |
[Emergency checklist in hypertensive crisis].
Topics: Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Clonidine; Diuretics; Emergencies; Female; Furosemide; Hospitalization; Humans; Hypertension; Male; Medical History Taking; Nifedipine; Nitrendipine; Pregnancy; Vasodilator Agents | 2006 |
Crystallization rate of amorphous nifedipine analogues unrelated to the glass transition temperature.
Topics: Calorimetry, Differential Scanning; Crystallization; Excipients; Hot Temperature; Hypromellose Derivatives; Methylcellulose; Nifedipine; Nitrendipine; Phase Transition; Polymers; Povidone; Temperature; Transition Temperature; Water | 2007 |
Differential effects of dihydropyridine calcium antagonists on doxorubicin-induced nephrotoxicity in rats.
Topics: Amlodipine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Calcium Channel Blockers; Creatinine; Doxorubicin; Glutathione; Glutathione Transferase; Kidney; Kidney Diseases; Male; Malondialdehyde; Nifedipine; Nitrendipine; Nitric Oxide; Nitric Oxide Synthase; Proteinuria; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2007 |
Signalling pathways involved in the contractile response to 5-HT in the human pulmonary artery.
Topics: Aged; Calcium; Escin; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Muscle Contraction; Myocardial Contraction; Nifedipine; Nitrendipine; Pulmonary Artery; Sarcoplasmic Reticulum; Serotonin; Signal Transduction; Spectrometry, Fluorescence | 2009 |
Differential roles of dihydropyridine calcium antagonist nifedipine, nitrendipine and amlodipine on gentamicin-induced renal tubular toxicity in rats.
Topics: Acetylglucosaminidase; Amlodipine; Animals; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Calcium Channel Blockers; Creatine; Gene Expression Regulation; Gentamicins; Glutathione; Glutathione Transferase; Kidney Tubules; Male; Malondialdehyde; Nifedipine; Nitrendipine; Nitric Oxide; Nitric Oxide Synthase; Proteinuria; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2009 |
Amino acid sensing by enteroendocrine STC-1 cells: role of the Na+-coupled neutral amino acid transporter 2.
Topics: Amino Acid Transport System A; Amino Acids; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cell Line, Tumor; Enteroendocrine Cells; Humans; Ion Channel Gating; Membrane Potentials; Mice; Nifedipine; Nitrendipine; Receptors, Calcium-Sensing; Receptors, G-Protein-Coupled; RNA Interference; Sodium; Time Factors; Transfection | 2010 |
Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine.
Topics: Administration, Intravenous; Administration, Oral; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Dihydropyridines; Heart; Hemodynamics; Male; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2012 |
Effect of calcium channel blockers on paraoxonase-1 (PON1) activity and oxidative stress.
Topics: Amlodipine; Aryldialkylphosphatase; Calcium Channel Blockers; Humans; Isradipine; Nifedipine; Nitrendipine; Oxidative Stress | 2014 |
A useful model capable of predicting the clearance of cytochrome 3A4 (CYP3A4) substrates in humans: validity of CYP3A4 transgenic mice lacking their own Cyp3a enzymes.
Topics: Alprazolam; Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Felodipine; Humans; Male; Mice; Mice, Transgenic; Microsomes, Liver; Midazolam; Nifedipine; Nitrendipine; Quinidine | 2014 |
In search of the mutual relationship between the structure, solid-state spectroscopy and molecular dynamics in selected calcium channel blockers.
Topics: Calcium Channel Blockers; Crystallization; Dihydropyridines; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Nifedipine; Nimodipine; Nitrendipine; Quantum Theory; Spectrophotometry, Infrared; X-Ray Diffraction | 2016 |