nifedipine has been researched along with nimodipine in 222 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 76 (34.23) | 18.7374 |
| 1990's | 64 (28.83) | 18.2507 |
| 2000's | 45 (20.27) | 29.6817 |
| 2010's | 32 (14.41) | 24.3611 |
| 2020's | 5 (2.25) | 2.80 |
| Authors | Studies |
|---|---|
| Herbette, LG; Mason, RP; Rhodes, DG | 1 |
| Böcker, RH; Guengerich, FP | 1 |
| Janis, RA; Triggle, DJ | 1 |
| Jacobson, KA; Jiang, JL; Melman, N; Olah, ME; Stiles, GL; van Rhee, AM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D | 1 |
| Cao, S; Chang, CC; Dunne, SF; Kai, L; Kang, S; Luan, CH; Pandey, P; Silverman, RB; Surmeier, DJ; Tian, X | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Reimão, JQ; Scotti, MT; Tempone, AG | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Sun, H | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Beaumont, K; Di, L; Maurer, TS; Smith, DA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Arribas, RL; Belluti, F; Bisi, A; Budriesi, R; Castellano, S; de Los Rios, C; Feoli, A; Gobbi, S; Micucci, M; Rampa, A | 1 |
| Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF | 1 |
| Chen, J; Han, C; Huang, MX; Li, Z; Liu, RD; Luo, HB; Tian, YJ; Wu, Y; Xie, X; Yang, YY; Yuan, Y | 1 |
| Montastruc, JL; Senard, JM | 1 |
| Bustamante, D; Fernandez, E; Kramer, V; Miranda, HF; Paeile, C; Pelissier, T; Pinardi, G; Saavedra, H | 1 |
| Floersheim, GL | 2 |
| Guido, S; Joseph, T | 1 |
| Fitoussi, G; Nègre-Salvayre, A; Salvayre, R; Troly, M | 1 |
| Ivleva, AIa; Lepakhin, VK; Martynov, IuS; Proskurin, VV; Udotova, SA | 1 |
| Mason, RP; Moisey, DM; Shajenko, L | 1 |
| Kocsis, JD; O'Regan, MH; Waxman, SG | 2 |
| Gergeĺ, D; Misík, V; Ondrias, K; Stasko, A | 1 |
| Cuccaro, ML; Jacobs, LS; Lorenson, MY | 1 |
| Bolger, GT; O'Neill, SK | 1 |
| Deyo, RA; Disterhoft, JF; Thompson, LT | 1 |
| Ahr, G; Baunack, AR; Konrad-Dalhoff, I; Kraft, H; Kuhlmann, J; Rämsch, KD; Schmitz, H; Weihrauch, TR | 1 |
| Dong, H; Lu, YQ; Wang, Q; Yang, QQ; Yang, ZC | 1 |
| Bäuerle, HD; Seelig, J | 1 |
| Carlos, AD; Ikemoto, N; Kang, JJ; Ohkusa, T; Smilowitz, H | 1 |
| Tian, B | 1 |
| Köhler, H; Marx, M; Merkel, F; Meyer zum Büschenfelde, KH; Weber, M | 1 |
| Czyrak, A; Maj, J; Mogilnicka, E; Siwanowicz, J | 1 |
| Ransom, BR; Stys, PK; Waxman, SG | 1 |
| Batra, S | 1 |
| Carpenter, CL; Greenberg, DA; Messing, RO | 1 |
| Bellemann, P; Franckowiak, G | 1 |
| Hess, P; Reeves, JP; Rosenberg, RL; Smilowitz, H; Tsien, RW | 1 |
| Leslie, SW; Woodward, JJ | 1 |
| Bradford, HF; White, EJ | 1 |
| Greenberg, DA | 1 |
| Traber, J; Van Rooijen, LA | 1 |
| Artalejo, CR; Garcia, AG | 1 |
| Carvalho, AP; Carvalho, CA; Coutinho, OP | 1 |
| Andresen, MC; Kunze, DL; Torres, LA | 1 |
| Juhász, O; Orlický, J; Ruscák, M; Zachar, J | 1 |
| Douglas, WW; Taraskevich, PS | 1 |
| Mikkelsen, EO; Nyborg, NC | 1 |
| Archer, DP; Pappius, HM | 1 |
| Jin, L; Lei, YP; Liu, LS; Wang, W; Zhang, XE; Zhao, Y | 1 |
| Herbette, LG; Rhodes, DG; Vant Erve, YM | 1 |
| Ferry, DR; Glossmann, H; Goll, A; Linn, T | 1 |
| Barnett, DB; Walley, TJ; Woods, KL | 1 |
| Bae, SJ; Herbette, LG; Kitamura, S; Sturtevant, JM | 1 |
| Kuwaki, T; Nishimura, T; Ono, T; Satoh, H; Shibayama, F; Yamashita, T | 1 |
| Kamei, C; Kurokawa, K; Tasaka, K | 1 |
| Qin, WC; Zhang, JT | 1 |
| Bolger, GT; Ruzycky, A; Triggle, DJ; Yousif, FB | 1 |
| Dandona, P; Jeremy, JY; Mikhailidis, DP | 1 |
| Boldt, J; Hempelmann, G; Kling, D; Ratthey, K; Von Bormann, B | 1 |
| Baky, S; Nademanee, K; Singh, BN | 1 |
| Duncker, DJ; Saxena, PR; Verdouw, PD | 1 |
| Boldt, J; Hempelmann, G; Kling, D; Ratthey, K; Russ, W; von Bormann, B | 1 |
| Nishikibe, M | 1 |
| Cheng, XJ; Zhang, JT | 1 |
| Duncker, DJ; Saxena, PR; Van der Weij, LP; Verdouw, PD; Yland, MJ | 1 |
| Jónsdóttir, M; Meyer, JS; Rogers, RL | 1 |
| Shimizu, Y | 1 |
| Kato, H; Takata, Y | 1 |
| Graefe, KH; Rämsch, KD; Scherling, D; Sommer, J; Ziegler, R | 1 |
| Allen, GS | 1 |
| Dowell, RE; Meyer, JS; Nance, M; Walker, M; Zetusky, WJ | 1 |
| Solomon, GD | 1 |
| Aizawa, T; Enyeart, JJ; Hinkle, PM | 1 |
| Barradas, MA; Dandona, P; Jeremy, JY; Mikhailidis, DP | 1 |
| Bonstelle, C; Spetzler, RF; Zabramski, J | 1 |
| Hager, WD; Katz, AM; Messineo, FC; Pappano, AJ | 1 |
| Bellemann, P | 2 |
| Kirley, TL; Schwartz, A | 1 |
| Enyeart, JJ; Hinkle, PM | 1 |
| Kojima, I; Kojima, K; Rasmussen, H | 1 |
| Grupp, G; Grupp, IL; Schwartz, A; Vaghy, PL; Williams, JS | 1 |
| Müller-Schweinitzer, E; Neumann, P | 1 |
| Andrenyak, DM; Epstein, PM; Fiss, K; Hachisu, R | 1 |
| De Zoeten, K; Timmermans, PB; Van Meel, JC; Van Zwieten, PA; Wilffert, B | 1 |
| Ferry, DR; Glossmann, H; Goll, A | 1 |
| Gould, RJ; Murphy, KM; Snyder, SH | 1 |
| Itoh, T; Kanmura, Y; Kuriyama, H; Makita, Y; Suzuki, H | 1 |
| Freedman, SB; Miller, RJ | 1 |
| Janis, RA; Pan, M | 1 |
| Hardenberg, J; Meyer, JS | 1 |
| Peroutka, SJ | 1 |
| Honn, KV; Onoda, JM; Sloane, BF | 1 |
| Dowell, R; Hardenberg, J; Mathew, N; Meyer, JS | 1 |
| Clincke, GH; Wauquier, A | 1 |
| Barr, EM; Daniell, LC; Leslie, SW | 1 |
| Altura, BM; Altura, BT | 1 |
| Kowalski, TE; Taylor, DG | 1 |
| DePover, A; DiSalvo, J; Grupp, G; Grupp, IL; Millard, RW; Schwartz, A | 1 |
| Hachisu, M; Pappano, AJ | 1 |
| Bolger, GT; Gengo, P; Janis, RA; Klockowski, R; Luchowski, E; Siegel, H; Triggle, AM; Triggle, DJ | 1 |
| Askholt, J; Jensen, PH; Nielsen-Kudsk, F | 1 |
| Edvinsson, L; Johansson, BB; Larsson, B; MacKenzie, ET; Skärby, T; Young, AR | 1 |
| Satake, N; Shibata, S; Takagi, T | 1 |
| Andersson, KE; Brandt, L; Edvinsson, L; Ljunggren, B | 1 |
| Bolger, GT; Janis, RA; Maurer, SC; Sarmiento, JG; Triggle, DJ | 1 |
| Bellemann, P; Ferry, D; Glossmann, H; Lübbecke, F | 1 |
| Dusseau, J; Hutchins, PM | 1 |
| Abraham, WC; Christie, BR | 1 |
| Filloux, FM; Fitts, RC; Skeen, GA; White, HS | 1 |
| Arneric, SP; Donnelly-Roberts, DL; Sullivan, JP | 1 |
| Dall'Olio, R; Gaggi, R; Gianni, AM; Roncada, P | 2 |
| Floersheim, GL; Racine, C | 1 |
| Breuel, HP; Heine, PR; Kuhlmann, J; Mück, W; Niklaus, H; Schmage, N | 1 |
| Bernardi, G; Bonci, A; Calabresi, P; Mercuri, NB; Stefani, A; Stratta, F | 1 |
| Gealy, R; Levitan, ES; Takimoto, K; Trimmer, JS | 1 |
| Hongo, K; Kobayashi, S | 1 |
| Wessely, P; Wöber-Bingöl, C | 1 |
| Edamatsu, R; Hiramatsu, M; Mori, A; Mori, I; Ohba, S | 1 |
| Cont, R; Gaggi, R; Gianni, AM | 1 |
| Bao, YD; Yang, YS; Yao, Y; Zhu, H | 1 |
| Bagchi, D; Das, DK; Engelman, RM; Liu, X; Nath, D; Rousou, JA; Wei, Z | 1 |
| Clements, MP; Rose, SP; Tiunova, A | 1 |
| Hume, RI; Lin, X; Nuttall, AL | 1 |
| Barth, HL; Hempelmann, RG; Mehdorn, HM; Pradel, RH; Ziegler, A | 1 |
| Roine, RO | 1 |
| Fukui, M; Ikezaki, K; Matsukado, K; Nomura, T | 1 |
| Bonev, AD; Heppner, TJ; Kau, ST; Li, JH; Nelson, MT; Ohnmacht, CJ; Trainor, DA; Yasay, GD | 1 |
| Furukawa, T; Katsuragi, T; Usune, S | 1 |
| Okopién, B; Trzeciak, HI | 1 |
| Alfaro, MJ; Colado, MI; del Val, VL; Goicoechea, C; Martín, MI | 1 |
| Alfaro, MJ; Martín, MI; Martín, S; Ormazabal, MJ; Viveros, MP | 1 |
| Castleden, CM; Elliott, RA; Norman, RI; Parker, SG; Whitaker, RP | 1 |
| Cohen, C; Perrault, G; Sanger, DJ | 1 |
| Bernardi, G; Calabresi, P; D'Angelo, V; Pisani, A; Tozzi, A | 1 |
| Borst, JG; Sakmann, B; Wu, LG | 1 |
| Foehring, RC; Pineda, JC; Waters, RS | 1 |
| El Ganouni, S; Hakkou, F; Tazi, A | 1 |
| Antkiewicz-Michaluk, L; Karolewicz, B; Michaluk, J; Vetulani, J | 1 |
| Cioffi, GA | 1 |
| Bisenieks, E; Briede, J; Daija, D; Duburs, G; Makarova, N; Poikans, J; Uldriķis, J | 1 |
| Garbarino, S; Gesino, D; Massimilla, S; Ogliastro, C; Sannita, WG | 1 |
| Jaroszkiewicz, E; Marciniec, B; Ogrodowczyk, M; Patterson, LH; Taiwo, FA | 1 |
| Da Silva, FH; Ghijsen, WE; Leenders, AG; Scholten, G; Wiegant, VM | 1 |
| Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S | 1 |
| Botta, L; Masetto, S; Perin, P; Soto, E; Valli, P; Vega, R; Zucca, G | 1 |
| Hara, I; Taya, K; Watanabe, Y; Zhang, J | 1 |
| Grant, KA; Green-Jordan, K | 1 |
| McGrath, JJ; Soares, KV | 1 |
| Adame, M; Carrascosa, F; Fidalgo, I; Iribarren, MJ; Monedero, P; Sáez-Fernández, AN; Zarauza, R | 1 |
| Easter, A; Spruce, AE | 1 |
| Janicak, PG; Levy, NA | 1 |
| Najarian, T; Traut, TW | 1 |
| Baillie, N; Chaisewikul, R; Marson, AG | 1 |
| Chang, HT; Chen, WC; Huang, JK; Jan, CR; Jiann, BP; Lu, YC; Su, W; Yu, CC | 1 |
| Arakawa, Y; Nishijima, C; Shimizu, N; Urushidani, T | 1 |
| Barad, M; Blouin, AM; Cain, CK | 1 |
| Kurkova, KS; Svetyĭ, LI | 1 |
| Szász, G | 1 |
| Campagnola, M; Cominacini, L; Davoli, A; Fratta Pasini, A; Garbin, U; Lo Cascio, V; Nava, C; Pastorino, AM; Rossato, P | 1 |
| Li, JX; Liang, JH; Liu, RK; Zhang, Q; Zheng, JW | 1 |
| Gall, CM; Lauterborn, JC; Lynch, G; Pinkstaff, JK; Xie, Y | 1 |
| Nedergaard, OA; Uhrenholt, TR | 1 |
| Azenabor, AA; Chaudhry, AU; Yang, S | 1 |
| Kato, M; Sakuma, Y; Watanabe, M | 1 |
| Camargo, C; Núñez-Vergara, LJ; Ortiz, ME; Squella, JA | 1 |
| Chen, B; Han, R; Li, JX; Liang, JH; Lu, Y; Wang, XH; Ye, XF; Zhang, P | 1 |
| Burakov, AM; Grinenko, AIa; Karandashova, GF; Krupitskiĭ, EM; Priputina, LS; Romanova, TN; Slavina, TIu; Vostrikov, VV | 1 |
| Barclay, LR; Ingold, KU; Lin, S; Litwinienko, G; MacLean, PD; Mulder, P | 1 |
| Badawi, JK; Bross, S; Kamp, S; Kwon, ST; Langbein, S; Li, H | 1 |
| Mielcarek, J; Naskrent, M | 1 |
| Cooke, IM; Xu, SH | 1 |
| Choi, YM; Chung, S; Jang, JY; Kang, YK; Kim, SH; Park, MK | 1 |
| Ingermann, RL; Zuccarelli, MD | 1 |
| Lee, J; Rajakumar, N; Rushlow, WJ | 1 |
| García-Bereguiaín, MA; Gutiérrez-Merino, C; Martín-Romero, FJ; Samhan-Arias, AK | 1 |
| Bishnoi, M; Chopra, K; Kulkarni, SK | 1 |
| Gupta, A; Mishra, P; Ray, SB; Verma, D; Wadhwa, S | 1 |
| Chen, TJ; Hwang, GS; Wang, PS; Wang, SW | 1 |
| Gold, MS; Zhang, XL | 1 |
| Kobayashi, Y; Matsui, T; Tanaka, M; Wang, Z; Watanabe, S | 1 |
| An Haack, K; Bennett, MJ; Li, H; Narayan, SB; Tan, L; Warnock, A | 1 |
| Ceron, CS; Gerlach, RF; Guimaraes, DA; Marçal, DM; Martins-Oliveira, A; Rizzi, E; Tanus-Santos, JE | 1 |
| Arien-Zakay, H; Lazarovici, P; Lecht, S; Lelkes, PI; Matzner, H; Rotfeld, E; Tabakman, R; Yaka, R | 1 |
| Krzemiński, TF; Mitręga, KA; Porc, M; Varghese, B | 1 |
| Hasan, M; Marson, AG; Pulman, J | 1 |
| De Villiers, MM; Ferg, E; Francis, F; Grooff, D | 1 |
| Daschil, N; Humpel, C | 1 |
| Chudoba, D; Drużbicki, K; Jarek, M; Jenczyk, J; Kiwilsza, A; Mielcarek, J; Pajzderska, A; Wąsicki, J | 1 |
| Chen, J; Sanderson, MJ | 1 |
| Herzfeld, E; Scheller, C; Speh, L; Strauss, C | 1 |
| Chmiel, K; Knapik-Kowalczuk, J; Paluch, M; Rams-Baron, M; Tu, W | 1 |
| Aamodt, EJ; Dwyer, DS; Kasap, M; Sagrera, CE | 1 |
| Dehghani, F; Ghadban, C; Hohmann, T; Hohmann, U; Kleine, J; Scheller, C; Schmidt, M; Strauss, C | 1 |
| Belal, F; Elmansi, H; Hadad, G; Roshdy, A; Salam, RA | 1 |
16 review(s) available for nifedipine and nimodipine
| Article | Year |
|---|---|
Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes.
Topics: Cell Membrane; Chemical Phenomena; Chemistry, Physical; Kinetics; Lipid Bilayers; Membrane Lipids; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship | 1991 |
New developments in Ca2+ channel antagonists.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Electrophysiology; Heart; Humans; Ion Channels; Muscle Relaxation; Muscle, Smooth; Potassium; Sodium; Structure-Activity Relationship; Substrate Specificity | 1983 |
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells | 2022 |
[Calcium channel blockers and prevention of migraine].
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Diltiazem; Flunarizine; Humans; Migraine Disorders; Nifedipine; Nimodipine; Verapamil | 1992 |
Calcium channel antagonists and the treatment of migraine.
Topics: Calcium; Calcium Channel Blockers; Cinnarizine; Diltiazem; Flunarizine; Humans; Ion Channels; Kinetics; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil | 1986 |
Second-generation calcium antagonists: search for greater selectivity and versatility.
Topics: Animals; Bepridil; Calcium Channel Blockers; Cinnarizine; Electrophysiology; Flunarizine; Heart; Humans; Lidoflazine; Muscle, Smooth, Vascular; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyrrolidines; Structure-Activity Relationship | 1985 |
Comparative efficacy of calcium antagonist drugs in the prophylaxis of migraine.
Topics: Calcium Channel Blockers; Cinnarizine; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Flunarizine; Humans; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil | 1985 |
Are dihydropyridine binding sites voltage sensitive calcium channels?
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; Ion Channels; Muscle, Smooth; Muscles; Myocardium; Neurons; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyridines | 1984 |
Calcium antagonists for the treatment of vasospasm following subarachnoid haemorrhage.
Topics: Animals; Calcium Channel Blockers; Cerebrovascular Circulation; Diltiazem; Humans; Ischemic Attack, Transient; Nicardipine; Nifedipine; Nimodipine; Subarachnoid Hemorrhage | 1993 |
[Calcium channel blockers in therapy of neurologic diseases].
Topics: Brain Ischemia; Calcium Channel Blockers; Cluster Headache; Flunarizine; Humans; Migraine Disorders; Nifedipine; Nimodipine | 1993 |
Diltiazem, nifedipine, nimodipine or verapamil for neuroleptic-induced tardive dyskinesia.
Topics: Antipsychotic Agents; Calcium Channel Blockers; Diltiazem; Dyskinesia, Drug-Induced; Humans; Nifedipine; Nimodipine; Verapamil | 2000 |
Calcium channel antagonists for the treatment of bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Humans; Lithium Compounds; Nifedipine; Nimodipine; Randomized Controlled Trials as Topic; Verapamil | 2000 |
Calcium antagonists as an add-on therapy for drug-resistant epilepsy.
Topics: Anticonvulsants; Calcium Channel Blockers; Drug Resistance; Epilepsy; Flunarizine; Humans; Nifedipine; Nimodipine; Randomized Controlled Trials as Topic | 2001 |
Calcium antagonists as an add-on therapy for drug-resistant epilepsy.
Topics: Anticonvulsants; Calcium Channel Blockers; Drug Resistance; Drug Therapy, Combination; Epilepsy; Flunarizine; Humans; Nifedipine; Nimodipine; Randomized Controlled Trials as Topic | 2013 |
15 trial(s) available for nifedipine and nimodipine
| Article | Year |
|---|---|
[Calcium channel blockers and prevention of migraine].
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Diltiazem; Flunarizine; Humans; Migraine Disorders; Nifedipine; Nimodipine; Verapamil | 1992 |
[Calcium antagonists in the treatment of cerebrovascular diseases].
Topics: Adult; Aged; Brain Ischemia; Carotid Artery, Internal; Carotid Stenosis; Cerebrovascular Circulation; Female; Humans; Male; Middle Aged; Nifedipine; Nimodipine | 1992 |
Effect of the calcium antagonists nifedipine, nitrendipine, nimodipine and nisoldipine on oesophageal motility in man.
Topics: Administration, Oral; Adult; Calcium Channel Blockers; Double-Blind Method; Esophagogastric Junction; Esophagus; Humans; Male; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Peristalsis; Pressure | 1991 |
Influence of nimodipine and nifedipine on intrapulmonary shunting--a comparison to other vasoactive drugs.
Topics: Blood Pressure; Cardiac Output; Dopamine; Heart Rate; Humans; Male; Middle Aged; Nifedipine; Nimodipine; Nitroglycerin; Pulmonary Artery; Pulmonary Circulation; Pulmonary Gas Exchange; Vascular Resistance | 1987 |
Low-dose fentanyl analgesia modified by calcium channel blockers in cardiac surgery.
Topics: Analgesia; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Artery Bypass; Fentanyl; Humans; Male; Middle Aged; Nifedipine; Nimodipine; Random Allocation | 1987 |
Role of calcium antagonists in cerebral arterial spasm.
Topics: Animals; Calcium Channel Blockers; Cerebral Arteries; Clinical Trials as Topic; Dogs; Double-Blind Method; Femoral Artery; Humans; In Vitro Techniques; Ischemic Attack, Transient; Isometric Contraction; Nicotinic Acids; Nifedipine; Nimodipine; Prospective Studies; Subarachnoid Hemorrhage; Vasoconstriction | 1985 |
Migraine and cluster headache treatment with calcium antagonists supports a vascular pathogenesis.
Topics: Calcium Channel Blockers; Cerebrovascular Circulation; Clinical Trials as Topic; Female; Hemodynamics; Humans; Male; Nicotinic Acids; Nifedipine; Nimodipine; Vascular Headaches; Verapamil | 1985 |
Comparative efficacy of calcium antagonist drugs in the prophylaxis of migraine.
Topics: Calcium Channel Blockers; Cinnarizine; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Flunarizine; Humans; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil | 1985 |
Clinical effectiveness of calcium entry blockers in prophylactic treatment of migraine and cluster headaches.
Topics: Adult; Calcium Channel Blockers; Cerebrovascular Circulation; Clinical Trials as Topic; Cluster Headache; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Random Allocation; Vascular Headaches; Vasomotor System; Verapamil | 1983 |
The pharmacology of calcium channel antagonists: a novel class of anti-migraine agents?
Topics: Calcium Channel Blockers; Cerebrovascular Circulation; Clinical Trials as Topic; Cyproheptadine; Diltiazem; Humans; Migraine Disorders; Muscle, Smooth, Vascular; Nicotinic Acids; Nifedipine; Nimodipine; Vasomotor System; Verapamil | 1983 |
Clinical and hemodynamic effects during treatment of vascular headaches with verapamil.
Topics: Adult; Aged; Calcium Channel Blockers; Cerebrovascular Circulation; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Nicotinic Acids; Nifedipine; Nimodipine; Vascular Headaches; Verapamil | 1984 |
The influence of nimodipine on hemodynamic parameters and peak and trough plasma concentrations of nifedipine chronically administered to elderly hypertensive patients.
Topics: Aged; Blood Pressure; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Interactions; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nimodipine; Pulse | 1995 |
Plasma concentration and CNS effects of Ca antagonists darodipine and nimodipine after single-dose oral administration to healthy volunteers.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Central Nervous System; Electroencephalography; Heart Rate; Humans; Male; Neuropsychological Tests; Nifedipine; Nimodipine | 1999 |
A comparative study with oral nifedipine, intravenous nimodipine, and magnesium sulfate in postoperative analgesia.
Topics: Administration, Oral; Adult; Aged; Analgesics; Analgesics, Opioid; Analysis of Variance; Calcium Channel Blockers; Chi-Square Distribution; Colon; Double-Blind Method; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Intravenous; Magnesium Sulfate; Male; Middle Aged; Morphine; Nifedipine; Nimodipine; Pain Measurement; Pain, Postoperative; Placebos; Receptors, N-Methyl-D-Aspartate; Rectum | 2000 |
[The efficacy of calcium channel blockers in the treatment of affective disorders and pathologic drive for alcohol in patients with alcoholism in the remission period].
Topics: Adult; Alcoholism; Calcium Channel Blockers; Double-Blind Method; Drive; Humans; Mood Disorders; Nifedipine; Nimodipine; Secondary Prevention; Treatment Outcome | 2004 |
193 other study(ies) available for nifedipine and nimodipine
| Article | Year |
|---|---|
Oxidation of 4-aryl- and 4-alkyl-substituted 2,6-dimethyl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyridines by human liver microsomes and immunochemical evidence for the involvement of a form of cytochrome P-450.
Topics: Chemical Phenomena; Chemistry; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Microsomes, Liver; NADP; Nifedipine; Oxidation-Reduction | 1986 |
Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; CHO Cells; Cricetinae; Dihydropyridines; Enzyme Inhibitors; Guinea Pigs; Humans; Isradipine; Molecular Structure; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship | 1996 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Dicarboxylic Acids; Dihydropyridines; Humans; Inhibitory Concentration 50; Molecular Structure; Nifedipine | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cricetinae; Dihydropyridines; Erythrocytes; Leishmania; Macaca mulatta; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Volume of Distribution in Drug Design.
Topics: Drug Design; Half-Life; Pharmacokinetics | 2015 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Polycyclic maleimide-based derivatives as first dual modulators of neuronal calcium channels and GSK-3β for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Calcium Channels, N-Type; Glycogen Synthase Kinase 3 beta; Humans; Maleimides; Polycyclic Compounds; Structure-Activity Relationship | 2019 |
Structural Modifications of Nimodipine Lead to Novel PDE1 Inhibitors with Anti-pulmonary Fibrosis Effects.
Topics: Animals; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Idiopathic Pulmonary Fibrosis; Nimodipine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats | 2022 |
Antinociceptive effects of Ca2+ channel blockers.
Topics: Analgesics; Analysis of Variance; Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Mice; Morphine; Nifedipine; Nimodipine; Pain Measurement; Rats; Rats, Wistar; Verapamil | 1992 |
Calcium antagonists protect mice against lethal doses of ionizing radiation.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Female; Male; Mice; Mice, Inbred C3H; Nifedipine; Nimodipine; Radiation Dosage; Radiation Injuries, Experimental; Radiation-Protective Agents | 1992 |
Effect of chemically different calcium antagonists on lipid profile in rats fed on a high fat diet.
Topics: Animals; Blood; Calcium; Clofibrate; Dietary Fats; Diltiazem; Felodipine; Lipids; Male; Nifedipine; Nimodipine; Rats; Rats, Inbred Strains; Verapamil | 1992 |
Comparative cytoprotective effect of dihydropyridine calcium channel blockers against the toxicity of oxidized low density lipoprotein for cultured lymphoid cells.
Topics: Calcium Channel Blockers; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Lipid Peroxidation; Lipoproteins, LDL; Lymphocytes; Nicardipine; Nifedipine; Nimodipine; Nisoldipine | 1992 |
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil | 1992 |
Nimodipine and nifedipine enhance transmission at the Schaffer collateral CA1 pyramidal neuron synapse.
Topics: Animals; Evoked Potentials; Hippocampus; In Vitro Techniques; Neurons; Nifedipine; Nimodipine; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1991 |
Spin-trapping and antioxidant properties of illuminated and nonilluminated nifedipine and nimodipine in heart homogenate and model system.
Topics: Animals; Antioxidants; Dihydropyridines; Electron Spin Resonance Spectroscopy; Free Radicals; Heart; Light; Lipid Peroxidation; Nifedipine; Nimodipine; Rats | 1991 |
Calcium release from pituitary secretory granules: modulation by thiols, disulfides, and dihydropyridine calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cattle; Cysteine; Cystine; Cytoplasmic Granules; Dihydropyridines; Disulfides; Dithiothreitol; Glutathione; Hydrogen-Ion Concentration; Mercaptoethanol; Nifedipine; Nimodipine; Pituitary Gland; Potassium Chloride; Sulfhydryl Compounds | 1990 |
The effects of dihydropyridine calcium channel modulators on pentylenetetrazole convulsions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Male; Mice; Nifedipine; Nimodipine; Seizures | 1990 |
Depolarization-dependent actions of dihydropyridines on synaptic transmission in the in vitro rat hippocampus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Dihydropyridines; Evoked Potentials; Female; Hippocampus; In Vitro Techniques; Light; Membrane Potentials; Neurons; Nifedipine; Nimodipine; Perfusion; Potassium; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1990 |
Nimodipine enhances spontaneous activity of hippocampal pyramidal neurons in aging rabbits at a dose that facilitates associative learning.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Aging; Analysis of Variance; Animals; Catheterization; Conditioning, Eyelid; Dose-Response Relationship, Drug; Female; Flunarizine; Hippocampus; Neurons; Nifedipine; Nimodipine; Rabbits; Software | 1990 |
Antagonistic effects of dihydropyridines and verapamil on CaCl2 and 5-HT-evoked contraction in porcine coronary artery.
Topics: Animals; Calcium Chloride; Coronary Vessels; Dihydropyridines; Felodipine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Nimodipine; Serotonin Antagonists; Swine; Verapamil | 1991 |
Interaction of charged and uncharged calcium channel antagonists with phospholipid membranes. Binding equilibrium, binding enthalpy, and membrane location.
Topics: Amlodipine; Calcium Channel Blockers; Magnetic Resonance Spectroscopy; Membrane Lipids; Membrane Potentials; Nifedipine; Nimodipine; Phospholipids; Phosphorus Isotopes; Thermodynamics | 1991 |
Effects of dihydropyridines on calcium release from the isolated membrane complex consisting of the transverse tubule and sarcoplasmic reticulum.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Kinetics; Microsomes; Muscles; Nifedipine; Nimodipine; Rabbits; Receptors, Nicotinic; Sarcoplasmic Reticulum | 1991 |
[Role of nimodipine and nifedipine on hemodynamics in anesthetic dogs].
Topics: Animals; Blood Pressure; Dogs; Heart Rate; Hemodynamics; Nifedipine; Nimodipine; Vascular Resistance | 1991 |
Additive effects of calcium antagonists on cyclosporin A-induced inhibition of T-cell proliferation.
Topics: Adult; Antibodies, Monoclonal; Calcium Channel Blockers; Cyclosporins; Diltiazem; Drug Synergism; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Nifedipine; Nimodipine; Phytohemagglutinins; T-Lymphocytes; Verapamil | 1990 |
Some behavioral effects of repeated administration of calcium channel antagonists.
Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Diltiazem; Exploratory Behavior; Male; Nifedipine; Nimodipine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1990 |
Effects of polyvalent cations and dihydropyridine calcium channel blockers on recovery of CNS white matter from anoxia.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Hypoxia, Brain; In Vitro Techniques; Nifedipine; Nimodipine; Optic Nerve; Rats | 1990 |
Characterization of [3H]-nitrendipine binding to uterine smooth muscle plasma membrane and its relevance to inhibition of calcium entry.
Topics: Animals; Binding, Competitive; Calcium; Cell Fractionation; Cell Membrane; Diethylstilbestrol; Diltiazem; Edetic Acid; Egtazic Acid; Female; Ion Channels; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Uterus | 1985 |
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cinnarizine; Diltiazem; Flunarizine; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Phenytoin; Pheochromocytoma; Potassium; Rats; Sodium; Verapamil | 1985 |
Different receptor affinities of the enantiomers of BAY K 8644, a dihydropyridine Ca channel activator.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; In Vitro Techniques; Kinetics; Nicotinic Acids; Nifedipine; Nimodipine; Rats; Receptors, Drug; Stereoisomerism | 1985 |
Calcium channels in planar lipid bilayers: insights into mechanisms of ion permeation and gating.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cattle; Electric Conductivity; Heart; In Vitro Techniques; Ion Channels; Lipid Bilayers; Nicotinic Acids; Nifedipine; Nimodipine; Potassium; Sarcolemma; Sodium | 1986 |
Bay K 8644 stimulation of calcium entry and endogenous dopamine release in rat striatal synaptosomes antagonized by nimodipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Corpus Striatum; Dopamine; Electric Stimulation; Kinetics; Male; Nicotinic Acids; Nifedipine; Nimodipine; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes | 1986 |
Enhancement of depolarization-induced synaptosomal calcium uptake and neurotransmitter release by Bay K8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cerebral Cortex; Ethanol; Glutamates; Glutamic Acid; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Norepinephrine; Potassium; Rats; Synaptosomes; Veratrine | 1986 |
Muscarinic cholinergic enhancement of inositide turnover in cerebral nerve endings is not mediated by calcium uptake.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcimycin; Calcium; Carbachol; Cinnarizine; Flunarizine; Male; Nerve Endings; Nicotinic Acids; Nifedipine; Nimodipine; Phosphatidic Acids; Phosphatidylinositols; Rats; Rats, Inbred Strains; Verapamil; Veratridine | 1986 |
Effects of Bay K 8644 on cat adrenal catecholamine secretory responses to A23187 or ouabain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Calcimycin; Calcium; Catecholamines; Cats; Dose-Response Relationship, Drug; Drug Synergism; Female; Magnesium; Male; Nicotinic Acids; Nifedipine; Nimodipine; Ouabain; Potassium; Sodium | 1986 |
Effects of Ca2+ channel blockers on Ca2+ translocation across synaptosomal membranes.
Topics: Adenosine Triphosphatases; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Diltiazem; Ion Channels; Nifedipine; Nimodipine; Sheep; Subcellular Fractions; Synaptic Membranes; Synaptosomes; Verapamil | 1986 |
Do calcium antagonists act directly on calcium channels to alter baroreceptor function?
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Ion Channels; Nifedipine; Nimodipine; Nitrendipine; Pressoreceptors; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Inhibition of Na+-Ca2+ exchange by calcium antagonists in rat brain microsomal membranes.
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Intracellular Membranes; Ion Channels; Ion Exchange; Microsomes; Nifedipine; Nimodipine; Pronase; Rats; Rats, Inbred Strains; Sodium; Verapamil | 1986 |
Effects of Bay K 8644 and other dihydropyridines on basal and potassium-evoked output of MSH from mouse melanotrophs in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Culture Techniques; Drug Interactions; Ion Channels; Male; Melanocyte-Stimulating Hormones; Mice; Nifedipine; Nimodipine; Pituitary Gland, Anterior; Potassium | 1986 |
Comparison of the inhibitory effects of nifedipine and nimodipine on mechanical responses of isolated rat coronary small arteries.
Topics: Animals; Arteries; Biomechanical Phenomena; Calcium; Coronary Vessels; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Nifedipine; Nimodipine; Potassium; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Vascular Resistance | 1987 |
Effects of two dihydropyridine calcium channel blockers on cerebral metabolism and blood flow in traumatized rat brain.
Topics: Animals; Blood Glucose; Brain; Brain Injuries; Calcium; Calcium Channel Blockers; Cerebrovascular Circulation; Energy Metabolism; Freezing; Ion Channels; Male; Nifedipine; Nimodipine; Parietal Lobe; Rats; Rats, Inbred Strains | 1986 |
Calcium antagonists in prevention of hypertension and stroke in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Calcium Channel Blockers; Cerebrovascular Disorders; Female; Hypertension; Male; Nifedipine; Nimodipine; Rats; Rats, Inbred SHR | 1989 |
Interaction of 1,4 dihydropyridine calcium channel antagonists with biological membranes: lipid bilayer partitioning could occur before drug binding to receptors.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Diffusion; Dogs; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nisoldipine; Rabbits; Receptors, Nicotinic; Sarcolemma; Sarcoplasmic Reticulum | 1989 |
Molecular approach to the calcium channel.
Topics: Animals; Benzothiazoles; Binding Sites; Brain; Calcium; Cattle; Chemical Phenomena; Chemistry; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Muscles; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles; Thiazoles; Verapamil | 1985 |
Effects of calcium channel blockers on in vitro platelet function in whole blood using single platelet counting.
Topics: Adult; Calcium Channel Blockers; Collagen; Diltiazem; Epinephrine; Female; Humans; In Vitro Techniques; Male; Nifedipine; Nimodipine; Platelet Aggregation Inhibitors; Platelet Count; Verapamil | 1989 |
The effects of calcium channel blocking drugs on the thermotropic behavior of dimyristoylphosphatidylcholine.
Topics: Calcium Channel Blockers; Calorimetry, Differential Scanning; Diltiazem; Dimyristoylphosphatidylcholine; Models, Biological; Nifedipine; Nimodipine; Nisoldipine; Thermodynamics; Verapamil | 1989 |
Nilvadipine attenuates ischemic degradation of gerbil brain cytoskeletal proteins.
Topics: Animals; Brain; Brain Ischemia; Calmodulin-Binding Proteins; Clathrin; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Gerbillinae; Male; Microtubule-Associated Proteins; Nicardipine; Nifedipine; Nimodipine | 1989 |
Hypotensive effects of dihydropyridine derivatives.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Hydralazine; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1985 |
[Nimodipine, nifedipine and vincamine improve amnesia induced by anisodine and sodium nitrite in rats and mice].
Topics: Amnesia; Animals; Male; Memory; Mice; Nifedipine; Nimodipine; Rats; Rats, Inbred Strains; Scopolamine Derivatives; Sodium Nitrite; Vinca Alkaloids; Vincamine | 1986 |
Ca2+ channel antagonist actions in bladder smooth muscle: comparative pharmacologic and [3H]nitrendipine binding studies.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Gallopamil; Guinea Pigs; In Vitro Techniques; Male; Microsomes; Muscarine; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Urinary Bladder | 1985 |
The effect of nifedipine, nimodipine and nisoldipine on agonist- and trauma-stimulated vascular prostacyclin synthesis in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium Channel Blockers; Epinephrine; Epoprostenol; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Wounds and Injuries | 1986 |
Systemic haemodynamics of dihydropyridine derivatives in conscious pigs with or without propranolol.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Hemodynamics; Nifedipine; Nimodipine; Nisoldipine; Propranolol; Swine; Vasodilation | 1988 |
Effect of the calcium entry blocker NB-818 on cerebral blood flow after unilateral carotid occlusion in the Mongolian gerbil.
Topics: Animals; Blood Pressure; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Circulation; Dihydropyridines; Female; Gerbillinae; Injections, Intraperitoneal; Male; Nifedipine; Nimodipine | 1988 |
[Effects of three cerebral vasodilators--nimodipine, nifedipine and vincamine on chemically-induced amnesia in rodents].
Topics: Amnesia; Animals; Learning; Male; Memory; Mice; Nifedipine; Nimodipine; Rats; Rats, Inbred Strains; Vasodilator Agents; Vincamine | 1986 |
Enhancement of vasoconstrictor and attenuation of vasodilator effects of 5-hydroxytryptamine by the calcium channel blockers nimodipine and nifedipine in the pig.
Topics: Animals; Carotid Arteries; Drug Synergism; Hemodynamics; Microspheres; Muscle, Smooth, Vascular; Nifedipine; Nimodipine; Regional Blood Flow; Serotonin; Swine; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 1987 |
Efficacy, side effects and tolerance compared during headache treatment with three different calcium blockers.
Topics: Adult; Calcium Channel Blockers; Female; Humans; Male; Middle Aged; Nifedipine; Nimodipine; Vascular Headaches; Verapamil | 1987 |
[Effect of the calcium entry blockers nicardipine and nimodipine on cerebral function following global anoxia in the rat].
Topics: Animals; Brain; Calcium Channel Blockers; Hypoxia, Brain; Male; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Rats; Rats, Inbred Strains; Resuscitation | 1986 |
Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hydralazine; Hypertension, Renal; Kinetics; Male; Nicardipine; Nifedipine; Nimodipine; Nisoldipine; Time Factors | 1986 |
Pharmacokinetics and metabolism of calcium-blocking agents nifedipine, nitrendipine, and nimodipine.
Topics: Biological Availability; Female; Half-Life; Humans; Individuality; Kinetics; Male; Nifedipine; Nimodipine; Nitrendipine | 1986 |
Dihydropyridine Ca2+ antagonists: potent inhibitors of secretion from normal and transformed pituitary cells.
Topics: Animals; Calcium Channel Blockers; Cell Line; Growth Hormone; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Pituitary Gland; Pituitary Neoplasms; Potassium Chloride; Prolactin; Rats; Thyrotropin-Releasing Hormone; Verapamil | 1985 |
An investigation into the effects of nifedipine and nimodipine on platelet function and vascular prostacyclin synthesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arteries; Blood Platelets; Calcium; Epoprostenol; In Vitro Techniques; Nifedipine; Nimodipine; Platelet Aggregation; Rats; Rats, Inbred Strains; Thromboxane A2 | 1985 |
Chronic cerebral vasospasm: effect of calcium antagonists.
Topics: Animals; Cerebral Angiography; Chronic Disease; Disease Models, Animal; Dogs; Injections; Ischemic Attack, Transient; Nicotinic Acids; Nifedipine; Nimodipine; Subarachnoid Hemorrhage; Subarachnoid Space | 1986 |
Cellular actions and pharmacology of calcium-channel blockers.
Topics: Actins; Action Potentials; Calcium; Calcium Channel Blockers; Cell Membrane; Drug Interactions; Extracellular Space; Heart; Homeostasis; Humans; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Myosins; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil | 1985 |
Interaction of the calcium channel activating 3H-BAY K 8644 and inhibiting 3H-verapamil with specific receptor sites on cultured beating myocardial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Calcium Channel Blockers; Cells, Cultured; Kinetics; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Receptors, Drug; Verapamil | 1984 |
Solubilization and affinity labeling of a dihydropyridine binding site from skeletal muscle: effects of temperature and diltiazem on [3H]dihydropyridine binding to transverse tubules.
Topics: Affinity Labels; Animals; Benzazepines; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Diltiazem; Intracellular Membranes; Kinetics; Microsomes; Microtubules; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rabbits; Receptors, Nicotinic; Temperature | 1984 |
Binding properties of a novel calcium channel activating dihydropyridine in monolayer cultures of beating myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium; Cells, Cultured; Female; Ion Channels; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Pregnancy; Rats; Time Factors | 1984 |
The calcium agonist Bay K 8644 stimulates secretion from a pituitary cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Cell Line; Clone Cells; Kinetics; Mice; Nicotinic Acids; Nifedipine; Nimodipine; Pituitary Neoplasms; Prolactin | 1984 |
Dihydropyridine calcium agonist and antagonist effects on aldosterone secretion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Dantrolene; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium; Stimulation, Chemical | 1984 |
Effects of dihydropyridine calcium channel modulators in the heart: pharmacological and radioligand binding correlations.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rats; Stimulation, Chemical | 1984 |
In vitro effects of calcium antagonists PN 200-110, nifedipine, and nimodipine on human and canine cerebral arteries.
Topics: Animals; Basilar Artery; Blood Physiological Phenomena; Calcium Channel Blockers; Cerebral Arteries; Dogs; Humans; In Vitro Techniques; Isradipine; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nicotinic Acids; Nifedipine; Nimodipine; Oxadiazoles; Serotonin; Vasoconstriction | 1983 |
Interaction of calcium antagonists with cyclic AMP phosphodiesterases and calmodulin.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium-Binding Proteins; Calmodulin; Chickens; Cytosol; Dogs; Humans; Kidney; Kinetics; Lymphocytes; Myocardium; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Pyridines; Rats; Spectrometry, Fluorescence | 1982 |
The inhibitory effect of newer calcium antagonists (nimodipine and PY-108-068) on vasoconstriction in vivo mediated by postsynaptic alpha 2-adrenoceptors.
Topics: Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Heart Rate; Male; Methoxamine; Nicotinic Acids; Nifedipine; Nimodipine; Norepinephrine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vasoconstriction | 1982 |
Differential labelling of putative skeletal muscle calcium channels by [3H]-nifedipine, [3H]-nitrendipine, [3H]-nimodipine and [3H]-PN 200 110.
Topics: Animals; Calcium Channel Blockers; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Kinetics; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles | 1983 |
A simple sensitive radioreceptor assay for calcium antagonist drugs.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cattle; Cell Membrane; Cerebral Cortex; Diltiazem; In Vitro Techniques; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Prenylamine; Radioligand Assay; Receptors, Nicotinic; Verapamil | 1983 |
Effects of nifedipine derivatives on smooth muscle cells and neuromuscular transmission in the rabbit mesenteric artery.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Female; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Rabbits; Synaptic Transmission | 1983 |
Stimulation of Na+,K+-ATPase of isolated smooth muscle membranes by the Ca2+ channel inhibitors, nimodipine and nitrendipine.
Topics: Animals; Brain; Guinea Pigs; Male; Membranes; Muscle, Smooth; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Ouabain; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1984 |
Antithrombogenic effects of calcium channel blockers: synergism with prostacyclin and thromboxane synthase inhibitors.
Topics: Adenosine Diphosphate; Benzofurans; Blood Platelets; Calcium Channel Blockers; Diltiazem; Drug Synergism; Epoprostenol; Humans; Nicotinic Acids; Nifedipine; Nimodipine; Oxidoreductases; Platelet Aggregation; Thrombin; Thromboxane A2; Thromboxane-A Synthase; Verapamil | 1984 |
Pharmacological protection against hypoxia-induced effects on medium-term memory in a two-way avoidance paradigm.
Topics: Animals; Avoidance Learning; Calcium Channel Blockers; Cerebral Cortex; Cinnarizine; Dose-Response Relationship, Drug; Flunarizine; Guinea Pigs; Hypoxia, Brain; Male; Memory; Mental Recall; Nicotinic Acids; Nifedipine; Nimodipine; Retention, Psychology; Vasodilation; Verapamil | 1984 |
45Ca2+ uptake into rat whole brain synaptosomes unaltered by dihydropyridine calcium antagonists.
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Male; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes | 1983 |
Pharmacologic inhibition of cerebral vasospasm in ischemia, hallucinogen ingestion, and hypomagnesemia: barbiturates, calcium antagonists, and magnesium.
Topics: Animals; Barbiturates; Brain Ischemia; Calcium Channel Blockers; Cerebral Arteries; Magnesium; Metabolic Diseases; Microcirculation; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Phencyclidine; Rats; Verapamil; Water Supply | 1983 |
Comparison of calcium channel inhibitors on vagal heart rate responses elicited by arterial baroreceptor reflexes in anesthetized dogs.
Topics: Acetylcholine; Anesthesia; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Heart Rate; In Vitro Techniques; Male; Nicotinic Acids; Nifedipine; Nimodipine; Nitroprusside; Norepinephrine; Pressoreceptors; Reflex; Vagus Nerve; Verapamil | 1984 |
Chronotropic, inotropic, and vasodilator actions of diltiazem, nifedipine, and verapamil. A comparative study of physiological responses and membrane receptor activity.
Topics: Animals; Benzazepines; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; Guinea Pigs; Heart Rate; In Vitro Techniques; Myocardial Contraction; Nicotinic Acids; Nifedipine; Nimodipine; Potassium; Pyridines; Receptors, Drug; Vasodilation; Verapamil | 1983 |
A comparative study of the blockade of calcium-dependent action potentials by verapamil, nifedipine and nimodipine in ventricular muscle.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Chickens; Electrophysiology; Heart Ventricles; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Ventricular Function; Verapamil | 1983 |
Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cinnarizine; Cobalt; Dose-Response Relationship, Drug; Drug Synergism; Flunarizine; Guinea Pigs; Ileum; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyridines; Structure-Activity Relationship; Verapamil | 1983 |
A comparative study of the pharmacodynamic effects of nimodipine and nifedipine in the isolated spontaneously beating rabbit heart.
Topics: Animals; Coronary Circulation; Depression, Chemical; Female; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Oxygen Consumption; Pyridines; Rabbits | 1983 |
Calcium antagonists: effects on cerebral blood flow and blood-brain barrier permeability in the rat.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Calcium Channel Blockers; Cerebrovascular Circulation; Ethanol; Male; Nicotinic Acids; Nifedipine; Nimodipine; Perhexiline; Rats; Rats, Inbred Strains; Xenon Radioisotopes | 1983 |
The inhibitory action of FR 34235 (a new Ca2+ entry blocker) as compared to nimodipine and nifedipine on the contractile response to norepinephrine, potassium and 5-hydroxytryptamine in rabbit basilar artery.
Topics: Animals; Basilar Artery; Calcium Channel Blockers; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicotinic Acids; Nifedipine; Nimodipine; Norepinephrine; Potassium; Pyridines; Rabbits; Serotonin | 1983 |
Effects of extracellular calcium and of calcium antagonists on the contractile responses of isolated human pial and mesenteric arteries.
Topics: Calcium; Calcium Channel Blockers; Dinoprost; Humans; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nicotinic Acids; Nifedipine; Nimodipine; Norepinephrine; Pia Mater; Potassium; Prostaglandins F; Serotonin | 1981 |
Binding of [3H]nimodipine to cardiac and smooth muscle membranes.
Topics: Animals; Calcium Channel Blockers; Kinetics; Male; Membranes; Microsomes; Muscle, Smooth; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rats | 1982 |
[3H]-Nimodipine and [3H]-nitrendipine as tools to directly identify the sites of action of 1,4-dihydropyridine calcium antagonists in guinea-pig tissues. Tissue-specific effects of anions and ionic strength.
Topics: Animals; Anions; Binding Sites; Binding, Competitive; Brain; Calcium Channel Blockers; Female; Guinea Pigs; Kidney; Kinetics; Lung; Male; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Organ Specificity; Osmolar Concentration; Pyridines | 1982 |
Calcium entry blockers stimulate vasoproliferation on the chick chorioallantoic membrane.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allantois; Animals; Cell Division; Chick Embryo; Chorion; Dose-Response Relationship, Drug; Nifedipine; Nimodipine; Verapamil | 1993 |
L-type voltage-sensitive calcium channel antagonists block heterosynaptic long-term depression in the dentate gyrus of anaesthetized rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Electric Stimulation; Electrochemistry; Hippocampus; Long-Term Potentiation; Male; Nifedipine; Nimodipine; Rats; Rats, Sprague-Dawley; Synapses | 1994 |
The dihydropyridine nitrendipine inhibits [3H]MK 801 binding to mouse brain sections.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Autoradiography; Binding, Competitive; Brain; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; N-Methylaspartate; Nifedipine; Nimodipine; Nitrendipine; Software; Verapamil | 1994 |
Functional modulation of human "ganglionic-like" neuronal nicotinic acetylcholine receptors (nAChRs) by L-type calcium channel antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Cadmium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Humans; Isradipine; Neuroblastoma; Neurons; Nicotine; Nifedipine; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Receptors, Nicotinic; Spider Venoms; Tumor Cells, Cultured; Verapamil | 1995 |
Peculiar effects of isradipine and darodipine on the rat brain dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium Channel Blockers; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Injections, Intraperitoneal; Isradipine; Male; Motor Activity; Nifedipine; Nimodipine; Parietal Lobe; Rats; Rats, Sprague-Dawley | 1995 |
Calcium antagonist radioprotectors do not reduce radiotherapeutic efficacy in three human tumor xenografts.
Topics: Adenocarcinoma; Animals; Calcium Channel Blockers; Colonic Neoplasms; Diltiazem; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Nifedipine; Nimodipine; Nitrendipine; Radiation-Protective Agents; Radiotherapy Dosage; Sarcoma, Ewing; Transplantation, Heterologous; Whole-Body Irradiation | 1995 |
Interaction between dihydropyridine calcium antagonists and morphine on the brain biogenic amines.
Topics: Animals; Biogenic Amines; Brain; Calcium Channel Blockers; Dopamine; Drug Interactions; Male; Morphine; Nifedipine; Nimodipine; Nisoldipine; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin | 1994 |
Effects of dihydropyridine calcium antagonists on rat midbrain dopaminergic neurones.
Topics: Action Potentials; Animals; Dopamine; In Vitro Techniques; Nifedipine; Nimodipine; Rats; Rats, Wistar; Substantia Nigra; Ventral Tegmental Area | 1994 |
Membrane depolarization inhibits Kv1.5 voltage-gated K+ channel gene transcription and protein expression in pituitary cells.
Topics: Amiloride; Animals; Calcium; Clone Cells; Down-Regulation; Gene Expression; Kv1.5 Potassium Channel; Meglumine; Membrane Potentials; Nifedipine; Nimodipine; Pituitary Neoplasms; Potassium Channels; Potassium Channels, Voltage-Gated; Potassium Chloride; Protein Biosynthesis; Rats; RNA, Messenger; Sodium; Sodium-Hydrogen Exchangers; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Metal ions affect neuronal membrane fluidity of rat cerebral cortex.
Topics: Animals; Cations; Cerebral Cortex; Cyclic N-Oxides; Edetic Acid; Egtazic Acid; Electron Spin Resonance Spectroscopy; Flunarizine; Kinetics; Male; Membrane Fluidity; Metals; Neurons; Nicardipine; Nifedipine; Nimodipine; Rats; Rats, Sprague-Dawley; Spin Labels; Synaptosomes | 1994 |
Comparison among the effects of nifedipine, nimodipine and nisoldipine on the brain biogenic amines of normal or haloperidol treated rats.
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Calcium Channel Blockers; Dopamine; Haloperidol; Male; Nifedipine; Nimodipine; Nisoldipine; Rats; Rats, Sprague-Dawley; Serotonin | 1993 |
[A voltage-clamp study on voltage-gated calcium channels translated in Xenopus oocytes by rat brain mRNA].
Topics: Animals; Brain Chemistry; Calcium Channels; Cells, Cultured; Embryo, Mammalian; Embryo, Nonmammalian; Female; Ion Channel Gating; Membrane Potentials; Microinjections; Nifedipine; Nimodipine; Oocytes; Rats; RNA, Messenger; Xenopus laevis | 1993 |
Radioprotective effects of calcium antagonists used alone or with other types of radioprotectors.
Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Diltiazem; Dimethyl Sulfoxide; Drug Combinations; Female; Flunarizine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Radiation-Protective Agents; Verapamil; Zinc | 1993 |
Attenuation of myocardial reperfusion injury by reducing intracellular calcium overloading with dihydropyridines.
Topics: Animals; Calcium; Coronary Circulation; Creatine Kinase; Dihydropyridines; Free Radical Scavengers; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Nimodipine; Nisoldipine; Perfusion; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 1993 |
omega-Conotoxin GVIA disrupts memory formation in the day-old chick.
Topics: Age Factors; Animals; Avoidance Learning; Calcium Channel Blockers; Chickens; Discrimination Learning; Dose-Response Relationship, Drug; Female; Male; Mental Recall; Nifedipine; Nimodipine; omega-Conotoxin GVIA; Pattern Recognition, Visual; Peptides; Retention, Psychology | 1995 |
Dihydropyridines and verapamil inhibit voltage-dependent K+ current in isolated outer hair cells of the guinea pig.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Cochlea; Guinea Pigs; Hair Cells, Auditory, Outer; Membrane Potentials; Nifedipine; Nimodipine; Patch-Clamp Techniques; Potassium Channel Blockers; Quinine; Verapamil | 1995 |
Effects of potassium channel openers in isolated human cerebral arteries.
Topics: Benzopyrans; Calcium Channel Blockers; Carbachol; Cerebral Arteries; Cromakalim; Culture Techniques; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanidines; Humans; Iloprost; Nifedipine; Nimodipine; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1995 |
Nimodipine in patients with heart disease.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Cerebrovascular Disorders; Clinical Trials as Topic; Contraindications; Coronary Disease; Humans; Hypertension; Meta-Analysis as Topic; Multicenter Studies as Topic; Neuroprotective Agents; Nifedipine; Nimodipine; Survival Analysis; Treatment Outcome; Ventricular Fibrillation | 1996 |
Effect of calcium antagonists on regional cerebral blood flow in transplanted rat brain tumors.
Topics: Analysis of Variance; Animals; Brain; Brain Neoplasms; Calcium Channel Blockers; Cerebrovascular Circulation; Diltiazem; Flunarizine; Glioma; Male; Neoplasm Transplantation; Nifedipine; Nimodipine; Rats; Rats, Wistar; Verapamil | 1996 |
Studies of the K(ATP) channel opening activity of the new dihydropyridine compound 9-(3-cyanophenyl)-3,4,6,7,9,10-hexahydro-1,8-(2H,5H)-acridined ione in bladder detrusor in vitro.
Topics: Acridines; Adenosine Triphosphate; Animals; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nimodipine; Patch-Clamp Techniques; Potassium Channels; Urinary Bladder | 1996 |
Discrimination by nimodipine, but not by nifedipine, between phasic and tonic contractions of guinea-pig taenia coli induced by K+ depolarization.
Topics: Animals; Calcium Channel Blockers; Colon; Dose-Response Relationship, Drug; Guinea Pigs; Hypertonic Solutions; In Vitro Techniques; Male; Manganese; Muscle Contraction; Muscle, Smooth; Neuromuscular Depolarizing Agents; Nifedipine; Nimodipine; Potassium | 1995 |
Modification of adrenergic reactivity in rat tail artery by dietary lipids and calcium channel antagonists.
Topics: Animals; Arteries; Body Weight; Calcium Channel Blockers; Diet, Atherogenic; Dietary Fats; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nimodipine; Nitrendipine; Norepinephrine; Rats; Rats, Wistar; Regional Blood Flow; Sympathetic Nervous System; Sympathomimetics; Tail | 1996 |
Behavioral and analgesic effects induced by administration of nifedipine and nimodipine.
Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electric Stimulation; Exploratory Behavior; Male; Motor Activity; Nifedipine; Nimodipine; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Vocalization, Animal; Weight Gain | 1996 |
Effects of nimodipine and nifedipine upon behavior and regional brain monoamines in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Calcium Channel Blockers; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Nifedipine; Nimodipine; Rats; Rats, Wistar; Serotonin | 1996 |
Effect of treatment with calcium antagonists in vitro and in vivo on the contractile response of isolated rat and human detrusor muscle.
Topics: Animals; Calcium Channel Blockers; Carbachol; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nimodipine; Rats; Rats, Wistar; Urinary Bladder; Urination Disorders; Verapamil | 1996 |
Effects of dihydropyridine Ca2+ channel blockers on the discriminative stimulus and the motor impairing effects of (+/-)-Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Discrimination, Psychological; Male; Mice; Motor Activity; Nicardipine; Nifedipine; Nimodipine | 1997 |
L-type Ca2+ channel blockers attenuate electrical changes and Ca2+ rise induced by oxygen/glucose deprivation in cortical neurons.
Topics: Animals; Brain Ischemia; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cytophotometry; Dantrolene; Energy Metabolism; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Glucose; Male; Membrane Potentials; Nifedipine; Nimodipine; Oxygen Consumption; Pyramidal Cells; Rats; Rats, Wistar; Tetrodotoxin; Time Factors | 1998 |
R-type Ca2+ currents evoke transmitter release at a rat central synapse.
Topics: Action Potentials; Animals; Baclofen; Brain Stem; Cadmium Chloride; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Neurons; Nickel; Nifedipine; Nimodipine; omega-Agatoxin IVA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Spider Venoms; Synapses | 1998 |
Specificity in the interaction of HVA Ca2+ channel types with Ca2+-dependent AHPs and firing behavior in neocortical pyramidal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Blockers; Calcium Channels; Cations, Divalent; Ion Transport; Membrane Potentials; Motor Cortex; Nerve Tissue Proteins; Nifedipine; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Pyramidal Cells; Somatosensory Cortex; Spider Venoms | 1998 |
Potential serotonergic interactions with the anxiolytic-like effects of calcium channel antagonists.
Topics: Animals; Anti-Anxiety Agents; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drinking; Environment; Male; Nifedipine; Nimodipine; Pyrimidines; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists | 1998 |
Effects of various Ca2+ channel antagonists on morphine analgesia, tolerance and dependence, and on blood pressure in the rat.
Topics: Analgesics, Opioid; Animals; Binding Sites; Blood Pressure; Calcium Channel Blockers; Cerebral Cortex; Drug Interactions; Drug Tolerance; Male; Morphine; Nifedipine; Nimodipine; Nitrendipine; Rats; Rats, Wistar; Substance-Related Disorders; Tritium; Verapamil | 1998 |
Three assumptions: ocular blood flow and glaucoma.
Topics: Blood Flow Velocity; Calcium Channel Blockers; Ciliary Arteries; Color Perception; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Nifedipine; Nimodipine; Optic Nerve; Retinal Artery; Ultrasonography, Doppler, Color; Visual Fields | 1998 |
Effects of some 1,4-dihydropyridine Ca antagonists on the blast transformation of rat spleen lymphocytes.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Lymphocyte Activation; Nicardipine; Nifedipine; Nimodipine; Rats; Spleen | 1999 |
Free radicals in irradiated drugs: an EPR study.
Topics: Calcium Channel Blockers; Dose-Response Relationship, Radiation; Electron Spin Resonance Spectroscopy; Felodipine; Free Radicals; Gamma Rays; Nifedipine; Nimodipine; Nitrendipine | 1999 |
Activity-dependent neurotransmitter release kinetics: correlation with changes in morphological distributions of small and large vesicles in central nerve terminals.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Cholecystokinin; Male; Microscopy, Electron; Neurotransmitter Agents; Nifedipine; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Potassium; Rats; Rats, Wistar; Synaptic Vesicles; Synaptosomes | 1999 |
Calcium channel activation and self-biting in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior | 1999 |
Calcium channels functional roles in the frog semicircular canal.
Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Dose-Response Relationship, Drug; Evoked Potentials; In Vitro Techniques; Membrane Potentials; Neurons, Afferent; Nifedipine; Nimodipine; omega-Agatoxin IVA; omega-Conotoxins; Physical Stimulation; Rana esculenta; Semicircular Canals | 2000 |
Appearance of highly sensitive cells to L-type Ca antagonist in cultured cerebellar granule cells.
Topics: Animals; Calcium; Cell Adhesion; Cells, Cultured; Cerebellum; Image Cytometry; Nicardipine; Nifedipine; Nimodipine; Polylysine; Rats; Rats, Wistar | 1999 |
Modulation of the ethanol-like discriminative stimulus effects of diazepam and phencyclidine by L-type voltage-gated calcium-channel ligands in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Central Nervous System Depressants; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Modulators; Isradipine; Ligands; Male; N-Methylaspartate; Nifedipine; Nimodipine; Phencyclidine; Rats; Rats, Long-Evans | 2000 |
Modulation of calcium current by recombinant GABA(B) receptors.
Topics: Animals; Baclofen; Calcium Channel Blockers; Calcium Channels; GABA Agonists; Glioma; Hybrid Cells; Membrane Potentials; Neuroblastoma; Nifedipine; Nimodipine; Norepinephrine; Protein Subunits; Receptors, GABA-B; Recombinant Proteins; Transfection | 2000 |
Nifedipine and nimodipine competitively inhibit uridine kinase and orotidine-phosphate decarboxylase: theoretical relevance to poor outcome in stroke.
Topics: Animals; Binding, Competitive; Brain; Calcium Channel Blockers; Cell Membrane; Humans; Neurons; Nifedipine; Nimodipine; Orotidine-5'-Phosphate Decarboxylase; Pharmacokinetics; Recovery of Function; Stroke; Treatment Outcome; Uridine Kinase | 2000 |
Effect of the organotin compound triethyltin on Ca2+ handling in human prostate cancer cells.
Topics: Calcium; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Drug Antagonism; Fura-2; Humans; Male; Nicardipine; Nifedipine; Nimodipine; Prostatic Neoplasms; Thapsigargin; Triethyltin Compounds; Tumor Cells, Cultured | 2002 |
Survival-promoting activity of nimodipine and nifedipine in rat motoneurons: implications of an intrinsic calcium toxicity in motoneurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Survival; Cells, Cultured; Motor Neurons; Neuroprotective Agents; Nifedipine; Nimodipine; Potassium; Rats; Sodium Channel Blockers; Tetrodotoxin | 2002 |
L-type voltage-gated calcium channels are required for extinction, but not for acquisition or expression, of conditional fear in mice.
Topics: Animals; Behavior, Animal; Calcium Channel Blockers; Calcium Channels, L-Type; Conditioning, Classical; Cues; Electroshock; Extinction, Psychological; Fear; Male; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Retention, Psychology | 2002 |
[Comparative clinico-pharmacological characteristics of nimodipine, nifedipine and foridon in the treatment of patients with ischemic stroke in late rehabilitative and residual periods].
Topics: Calcium Channel Blockers; Cerebrovascular Circulation; Female; Follow-Up Studies; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Nimodipine; Plethysmography; Stroke; Stroke Rehabilitation; Time Factors; Ultrasonography, Doppler, Transcranial; Vasodilator Agents | 2002 |
[Pharmaceutical chemistry of "dipines"].
Topics: Amlodipine; Calcium Channel Blockers; Dihydropyridines; Molecular Structure; Nifedipine; Nimodipine; Structure-Activity Relationship | 2002 |
Antioxidant activity of different dihydropyridines.
Topics: Amlodipine; Animals; Antioxidants; Cattle; Cells, Cultured; Dihydropyridines; Endothelium, Vascular; Fluoresceins; Humans; Lipoproteins, LDL; Molecular Structure; Nifedipine; Nimodipine; Reactive Oxygen Species | 2003 |
L-type Ca(2+) channel blockers inhibit the development but not the expression of sensitization to morphine in mice.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Mice; Morphine; Motor Activity; Narcotic Antagonists; Narcotics; Nifedipine; Nimodipine; Verapamil | 2003 |
Integrins regulate neuronal neurotrophin gene expression through effects on voltage-sensitive calcium channels.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Calcium Channel Blockers; Calcium Channels; Carbazoles; Cytochalasin D; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Exons; Gene Expression Regulation; Genes, fos; Glycoproteins; Hippocampus; Immunohistochemistry; In Situ Hybridization; In Vitro Techniques; Indole Alkaloids; Integrins; Neurotrophin 3; Nifedipine; Nimodipine; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptor, trkC; RNA Precursors; RNA, Messenger; Sesterterpenes; Terpenes; Tetrodotoxin; Time Factors; Transcription, Genetic; Trifluoperazine | 2003 |
Calcium channels involved in noradrenaline release from sympathetic neurones in rabbit carotid artery.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Carotid Artery, Common; Electric Stimulation; Female; Male; Neurons; Nifedipine; Nimodipine; Norepinephrine; omega-Conotoxin GVIA; Potassium Channel Blockers; Rabbits; Sympathetic Nervous System; Time Factors | 2003 |
Macrophage L-type Ca2+ channel antagonists alter Chlamydia pneumoniae MOMP and HSP-60 mRNA gene expression, and improve antibiotic susceptibility.
Topics: Animals; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cell Line; Chaperonin 60; Chelating Agents; Chlamydophila pneumoniae; Egtazic Acid; Gene Expression; Macrophages; Mice; Nifedipine; Nimodipine; RNA, Messenger | 2003 |
High expression of the R-type voltage-gated Ca2+ channel and its involvement in Ca2+-dependent gonadotropin-releasing hormone release in GT1-7 cells.
Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Calcium Channels, R-Type; Cell Line, Transformed; Electric Conductivity; Gene Expression; Gonadotropin-Releasing Hormone; Mice; Mice, Transgenic; Nickel; Nifedipine; Nimodipine; omega-Conotoxin GVIA; Patch-Clamp Techniques; Potassium; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spider Venoms | 2004 |
Oxidation of Hantzsch 1,4-dihydropyridines of pharmacological significance by electrogenerated superoxide.
Topics: Calcium Channel Blockers; Felodipine; Nifedipine; Nimodipine; Nitrendipine; Superoxides | 2004 |
L-type calcium channel blockers enhance 5-HTP-induced antinociception in mice.
Topics: 5-Hydroxytryptophan; Analgesics; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chloride; Chelating Agents; Drug Synergism; Egtazic Acid; Female; Fluoxetine; Injections, Intraventricular; Mice; Motor Activity; Nifedipine; Nimodipine; Pain Measurement; Pargyline; Selective Serotonin Reuptake Inhibitors; Verapamil | 2004 |
The L-type calcium channel blockers, hantzsch 1,4-dihydropyridines, are not peroxyl radical-trapping, chain-breaking antioxidants.
Topics: Acridines; Antioxidants; Benzene Derivatives; Biphenyl Compounds; Calcium Channel Blockers; Calcium Channels, L-Type; Chromans; Dihydropyridines; Free Radicals; Hydrazines; Kinetics; Nifedipine; Nimodipine; Oxidation-Reduction; Peroxides; Picrates; Styrene | 2006 |
Inhibitory effects of L- and T-type calcium antagonists on contractions of human detrusor muscle.
Topics: Adult; Aged; Analysis of Variance; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Carbachol; Diltiazem; Female; Humans; In Vitro Techniques; Male; Mibefradil; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Nimodipine; Potassium; Urinary Bladder; Verapamil | 2006 |
The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state.
Topics: Calcium Channel Blockers; Dihydropyridines; Electron Spin Resonance Spectroscopy; Felodipine; Gamma Rays; Humans; Hypertension; Models, Molecular; Molecular Conformation; Myocardial Ischemia; Nifedipine; Nimodipine | 2007 |
Voltage-gated currents of tilapia prolactin cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Female; Ion Channel Gating; Male; Nifedipine; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Pituitary Gland, Anterior; Potassium Channels; Prolactin; Sodium Channels; Spider Venoms; Tilapia | 2007 |
Nonselective cation channels are essential for maintaining intracellular Ca2+ levels and spontaneous firing activity in the midbrain dopamine neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Apamin; Calcium; Calcium Channel Blockers; Calcium Channels; Dopamine; Egtazic Acid; Imidazoles; Ion Channels; Membrane Potentials; Neurons; Nifedipine; Nimodipine; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Substantia Nigra; Tetrodotoxin | 2007 |
Calcium-induced quiescence of sperm motility in the bluegill (Lepomis macrochirus).
Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Chlorides; Cytoplasm; Dose-Response Relationship, Drug; Drug Interactions; Male; Manganese Compounds; Nifedipine; Nimodipine; Osmosis; Osmotic Pressure; Perciformes; Ruthenium Red; Semen; Sperm Motility; Spermatozoa; Strontium; Sulfonamides; Trifluoperazine | 2007 |
L-type calcium channel blockade on haloperidol-induced c-Fos expression in the striatum.
Topics: Animals; Antipsychotic Agents; Benzazepines; Blotting, Western; Calcium Channel Blockers; Calcium Channels, L-Type; Catalepsy; Cyclic AMP Response Element-Binding Protein; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; ets-Domain Protein Elk-1; Gene Expression; Genes, fos; Haloperidol; Immunohistochemistry; Male; Neostriatum; Nifedipine; Nimodipine; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1 | 2007 |
Hydrogen sulfide raises cytosolic calcium in neurons through activation of L-type Ca2+ channels.
Topics: 2-Amino-5-phosphonovalerate; Animals; Base Sequence; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebellum; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cytosol; Dizocilpine Maleate; DNA Primers; Excitatory Amino Acid Antagonists; Hydrogen Sulfide; Nifedipine; Nimodipine; Rats; Rats, Wistar; RNA, Messenger | 2008 |
Protective effect of L-type calcium channel blockers against haloperidol-induced orofacial dyskinesia: a behavioural, biochemical and neurochemical study.
Topics: Animals; Antioxidants; Antipsychotic Agents; Behavior, Animal; Calcium Channel Blockers; Calcium Channels, L-Type; Corpus Striatum; Diltiazem; Dopamine; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Movement Disorders; Nifedipine; Nimodipine; Random Allocation; Rats; Rats, Wistar; Serotonin; Verapamil | 2008 |
Nimodipine is more effective than nifedipine in attenuating morphine tolerance on chronic co-administration in the rat tail-flick test.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Male; Morphine; Nifedipine; Nimodipine; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Restraint, Physical | 2008 |
Effects of arecoline on testosterone release in rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arecoline; Benzylisoquinolines; Blotting, Western; Calcium Channels, L-Type; Cholinergic Agonists; Chorionic Gonadotropin; Colforsin; Leydig Cells; Luteinizing Hormone; Male; Nifedipine; Nimodipine; Phosphoproteins; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Testosterone | 2008 |
Dihydropyridine block of voltage-dependent K+ currents in rat dorsal root ganglion neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Dose-Response Relationship, Drug; Ganglia, Spinal; In Vitro Techniques; Male; Neurons; Nifedipine; Nimodipine; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley | 2009 |
Trp-His, a vasorelaxant di-peptide, can inhibit extracellular Ca2+ entry to rat vascular smooth muscle cells through blockade of dihydropyridine-like L-type Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Proliferation; Dipeptides; Male; Muscle, Smooth, Vascular; Nifedipine; Nimodipine; Rats; Rats, Wistar; Verapamil | 2010 |
Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracellular calcium levels by selected L-type calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Child; Drug Evaluation, Preclinical; Flunarizine; Humans; Intracellular Space; Membrane Glycoproteins; Molecular Chaperones; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Nicardipine; Nifedipine; Nimodipine; Potassium Chloride; RNA Interference; RNA, Small Interfering | 2011 |
Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension.
Topics: Amlodipine; Animals; Antioxidants; Aorta, Thoracic; Blood Pressure; Body Weight; Calcium Channel Blockers; Dihydropyridines; Down-Regulation; Gelatinases; Hypertension, Renovascular; Hypertrophy; Lipid Peroxides; Male; Matrix Metalloproteinase 2; Nifedipine; Nimodipine; Rats; Rats, Wistar; Reactive Oxygen Species; Tunica Media | 2011 |
Neuroprotective effects of nimodipine and nifedipine in the NGF-differentiated PC12 cells exposed to oxygen-glucose deprivation or trophic withdrawal.
Topics: Analysis of Variance; Animals; Calcium; Caspase 3; Catecholamines; Cell Differentiation; Cell Hypoxia; Glucose; Hippocampus; In Vitro Techniques; L-Lactate Dehydrogenase; Nerve Growth Factor; Neuroprotective Agents; Nifedipine; Nimodipine; PC12 Cells; Rats | 2012 |
Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine.
Topics: Administration, Intravenous; Administration, Oral; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Dihydropyridines; Heart; Hemodynamics; Male; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2012 |
Photostability of crystalline versus amorphous nifedipine and nimodipine.
Topics: Crystallization; Drug Stability; Kinetics; Nifedipine; Nimodipine; Photolysis; Vasodilator Agents; X-Ray Diffraction | 2013 |
Nifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses.
Topics: Animals; Axotomy; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Death; Cholinergic Neurons; Dopaminergic Neurons; Isradipine; Neuroimmunomodulation; Neuroprotective Agents; Nicardipine; Nifedipine; Nimodipine; Rats, Sprague-Dawley; Substantia Nigra; Tissue Culture Techniques; Ventral Tegmental Area; Verapamil | 2014 |
In search of the mutual relationship between the structure, solid-state spectroscopy and molecular dynamics in selected calcium channel blockers.
Topics: Calcium Channel Blockers; Crystallization; Dihydropyridines; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Nifedipine; Nimodipine; Nitrendipine; Quantum Theory; Spectrophotometry, Infrared; X-Ray Diffraction | 2016 |
Store-operated calcium entry is required for sustained contraction and Ca
Topics: Animals; Benzamides; Calcium; Calcium Channel Blockers; Calcium Channels; Female; Lung; Methacholine Chloride; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Nifedipine; Nimodipine; Pyrazoles | 2017 |
Nimodipine but Not Nifedipine Promotes Expression of Fatty Acid 2-Hydroxylase in a Surgical Stress Model Based on Neuro2a Cells.
Topics: Animals; Calcium Channel Blockers; Cell Death; Cell Differentiation; Cell Line; Cell Survival; Gene Expression; Heat-Shock Response; Mice; Mixed Function Oxygenases; Myelin Sheath; Neuroprotective Agents; Neurosurgical Procedures; Nifedipine; Nimodipine; Oxidative Stress; RNA, Messenger; Stress, Mechanical; Up-Regulation | 2017 |
Co-Stabilization of Amorphous Pharmaceuticals-The Case of Nifedipine and Nimodipine.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Dielectric Spectroscopy; Drug Compounding; Drug Stability; Molecular Dynamics Simulation; Nifedipine; Nimodipine | 2018 |
Novel pharmacological modulation of dystonic phenotypes caused by a gain-of-function mutation in the Na+ leak-current channel.
Topics: Animals; Boron Compounds; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dystonia; Ethoxzolamide; Flunarizine; Gain of Function Mutation; Gene Knockout Techniques; Ion Channels; Motor Disorders; Nifedipine; Nimodipine; Phenotype; Sodium Channels | 2020 |
Nimodipine Exerts Time-Dependent Neuroprotective Effect after Excitotoxical Damage in Organotypic Slice Cultures.
Topics: Hippocampus; Microglia; Neurons; Neuroprotective Agents; Nifedipine; Nimodipine | 2022 |
A Design-assisted Spectrofluorometric Method Utilizing a One-pot Fluorescent Probe for the Quantitation of some Calcium Channel Blockers.
Topics: Calcium Channel Blockers; Carbon; Fluorescent Dyes; Nifedipine; Nimodipine; Quantum Dots; Spectrometry, Fluorescence | 2023 |