nifedipine has been researched along with nicardipine in 437 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 264 (60.41) | 18.7374 |
| 1990's | 99 (22.65) | 18.2507 |
| 2000's | 48 (10.98) | 29.6817 |
| 2010's | 25 (5.72) | 24.3611 |
| 2020's | 1 (0.23) | 2.80 |
| Authors | Studies |
|---|---|
| Aisaka, K; Cho, H; Hamaguchi, M; Hayashimatsu, M; Hidaka, T; Mizuno, A; Ohnaka, Y; Shima, K; Takeuchi, Y; Ueda, M | 1 |
| Arrowsmith, JE; Blackburn, KJ; Burges, RA; Campbell, SF; Cross, PE; Gardiner, DG; Stubbs, JK | 1 |
| Arima, H; Fujita, S; Furuya, T; Inagaki, O; Isomura, Y; Kojima, T; Okada, M; Takenaka, T; Tamazawa, K; Terai, M | 1 |
| Fujita, M; Iso, T; Iwao, J; Kato, E; Kawashima, Y; Oya, M; Tabashi, K; Yamamoto, K | 1 |
| Janis, RA; Triggle, DJ | 1 |
| Jacobson, KA; Jiang, JL; Melman, N; Olah, ME; Stiles, GL; van Rhee, AM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Horinouchi, M; Komada, F; Nishiguchi, K; Ohmoto, N; Ohnishi, N; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y; Yokoyama, T | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D | 1 |
| Chen, CY; Kuo, SY; Yang, YH | 1 |
| Reimão, JQ; Scotti, MT; Tempone, AG | 1 |
| Sun, H | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF | 1 |
| Fujimoto, M; Iwanami, M; Kawai, R; Murakami, M; Shibanuma, T; Takahashi, K; Takenaka, T; Tamazawa, K | 1 |
| Haruno, A; Kanda, A; Miyake, H; Nagasaka, M | 1 |
| Crevat, A; Gallice, P; Kovacic, H | 1 |
| Ogihara, M | 4 |
| Chang, MS; Chen, CH; Chen, JW; Wang, SP | 1 |
| Kimura, H; Kusaba, T; Nagasawa, K; Otsuka, T; Sakata, T; Tada, Y; Tsuda, Y | 1 |
| Hirano, Y; January, CT; Moscucci, A | 1 |
| Brisac, AM; Dubray, C; Huguet, F; Roche, A | 1 |
| Fujiwara, T; Kohsaka, M; Mori, J; Satoh, H; Sogabe, K; Takakura, S; Tokuma, Y; Totsuka, Z | 1 |
| Fitoussi, G; Nègre-Salvayre, A; Salvayre, R; Troly, M | 1 |
| Dayer, P; Gauthey, L; Loew, F; Porchet, HC | 1 |
| Hata, H; Hojo, M; Katayama, O; Shibata, S; Tatsumi, H; Teramoto, N | 1 |
| D'Alonzo, S; Folli, G; Mettimano, M; Montebelli, MR; Savi, L | 1 |
| Boehme, P; Mak, IT; Weglicki, WB | 1 |
| Furuichi, Y; Kohsaka, M; Mori, J; Satoh, H; Takakura, S | 1 |
| Mustafa, AA | 1 |
| Kimura, T; Mukaiyama, O; Satoh, E; Satoh, S | 1 |
| Handa, J; Mori, J; Satoh, H; Shiino, A; Susumu, T; Takakura, S | 1 |
| Thomas, SH | 1 |
| González, CA; Paris, JV | 1 |
| Aoki, K; Kishimoto, T; Naruchi, T; Okamiya, Y; Takeshita, T; Tanabe, H | 1 |
| Handa, J; Inubushi, T; Kido, C; Matsuda, M; Morikawa, S; Shiino, A; Susumu, T | 1 |
| Dong, H; Lu, YQ; Wang, Q; Yang, QQ; Yang, ZC | 1 |
| Hua, C; Kelly, MT; Smyth, MR; Telting-Diaz, M | 1 |
| Glocke, MH; Griebel, A; Maetzel, FK; Teufel, WE | 1 |
| Dohmoto, H; Goto, A; Yamada, K; Yoshimoto, R | 1 |
| Ogawa, N | 1 |
| Masumoto, N; Miyake, A; Tanizawa, O; Tasaka, K | 1 |
| Furberg, C; Held, P; Yusuf, S | 1 |
| Inaba, M; Ishii, J; Itabashi, A; Katayama, S; Maruno, Y; Omoto, A | 1 |
| Bayram, A; Komsuoğlu, B; Komsuoğlu, SS; Sengün, B | 1 |
| Fujimoto, K; Inagaki, O; Kawashima, K; Oohata, H; Suzuki, T; Toda, H | 1 |
| Martsevich, SIu; Metelitsa, VI; Simkhaev, LS; Slastnikova, ID | 1 |
| A, SY; Chen, WR; Liu, F; Yang, YX; Zheng, HQ | 1 |
| Furui, H; Furumichi, T; Saito, H; Yamada, Y; Yamauchi, K; Yokota, M | 1 |
| Iso, T; Miyawaki, N; Nishimura, K; Yamauchi, H | 1 |
| Dayer, P; Porchet, HC | 1 |
| Kelly, J; Molyneux, P; Smith, SE; Thomas, SH | 1 |
| Donath, R; Gauthey, L; Herrmann, F; Jacot Des Combes, B; Loew, F; Petitot, C | 1 |
| Hashimoto, K; Motomura, S | 1 |
| Abe, T; Fujii, Y; Fujioka, S; Ina, H; Maseki, T; Yoshida, K | 1 |
| Ogihara, M; Sunaga, K | 1 |
| DeWood, MA; Wolbach, RA | 1 |
| Church, MK; Holgate, ST; Kim, YY | 1 |
| Kato, H; Takata, Y | 3 |
| Kimura, I; Kitani, H; Komagoe, H; Ohtani, J; Tada, S; Takahashi, K; Tanizaki, Y | 1 |
| Hatanaka, H; Takahashi, M; Tsukui, H | 1 |
| Kimura, I; Kitani, H; Komagoe, H; Maeda, M; Morinaga, H; Nakagawa, S; Ohtani, J; Takahashi, K; Tanizaki, Y | 1 |
| Kimura, I; Kitani, H; Komagoe, H; Ohtani, J; Sudo, M; Tada, S; Takahashi, K; Tanizaki, Y | 1 |
| Matsuo, K; Uchida, S | 1 |
| Advenier, C; Naline, E; Renier, A | 1 |
| Collu, R; Lafond, J | 1 |
| Handa, J; Kidooka, M; Matsuda, M | 1 |
| Ferry, DR; Glossmann, H; Goll, A | 1 |
| Hardman, HF; Preuss, KC; Shimshak, TM; Warltier, DC; Wynsen, JC | 1 |
| Furuta, T | 1 |
| Abe, K; Hagino, T; Kanazawa, M; Kasai, Y; Sato, M; Takeuchi, K; Tsunoda, K; Yasujima, M; Yoshinaga, K | 1 |
| Briand, V; Laurent, S; Schmitt, H | 1 |
| Chang, CC; Chiou, LC; Hong, SJ; Huang, CY; Hwang, LL | 1 |
| Azzollini, F; Cereda, A; Pelosi, G; Picca, M | 1 |
| Aizawa, T; Ishihara, M; Iwasaki, T; Niwa, A; Shinoda, T; Yamada, T | 1 |
| Adamson, P; Brammer, MJ; Campbell, IC; Hajimohamadreza, I | 1 |
| Batra, SC; Popper, LD | 1 |
| Arita, M; Baba, A; Masuyama, Y | 1 |
| Omae, T | 1 |
| Nakajima, S; Ninomiya, M; Tani, T; Ueda, M | 1 |
| Nagaoka, A; Shibota, M | 1 |
| Koibuchi, Y; Miura, S; Ohtsuka, M; Ono, T; Sakai, S; Shibayama, F | 1 |
| Barbier-Boehm, G; Enguerand, D; Marty, J; Pastor, C; Videcoq, M | 1 |
| Broustet, JP; Douard, H; Mora, B | 1 |
| Piepho, RW; Sowers, JR | 1 |
| Honn, KV; Nelson, KK; Onoda, JM; Taylor, JD | 1 |
| Calder, AA; Forbes, CD; Greer, IA; Walker, JJ | 1 |
| Littler, WA; Smith, SA | 1 |
| Charlier, AA; Cheron, P; Pouleur, H; Rousseau, MF; van den Berghe, G; Vincent, MF | 1 |
| Frais, MA; Hafizullah, M; Silke, B; Taylor, SH; Verma, SP | 1 |
| Lipkin, DP; Poole-Wilson, PA | 1 |
| Airiau, J; Bourbigot, B; Bressollette, L; Cledes, J; Guiserix, J; Morin, JF | 1 |
| Suga, T; Watanabe, T | 1 |
| Kuwaki, T; Nishimura, T; Ono, T; Satoh, H; Shibayama, F; Yamashita, T | 1 |
| Kamei, C; Kurokawa, K; Tasaka, K | 1 |
| Al-Mahmood, HA; el-Khatim, MS; Gumaa, KA; Thulesius, O | 1 |
| Frais, MA; Jackson, N; Midtbo, KA; Reynolds, G; Sharma, S; Silke, B; Taylor, SH; Verma, SP | 1 |
| Custro, N; Scafidi, V | 1 |
| Milovanovic, SR; Prostran, M; Prostran, MS; Varagic, VM; Vasiljevic, Z | 1 |
| Chhabra, A; Fairhurst, AS; Thayer, SA; Welcome, M | 1 |
| Inoue, K; Mitsui, I; Mukaiyama, T; Ogawa, M; Terashima, M | 1 |
| Adachi, K; Sakanashi, M; Takeo, S | 1 |
| Dubur, GJ; Gendvilienè, VI; Kimenis, AA; Macianskiene, RA; Narusevicius, EV; Selga, MJ; Simkhovich, BZ; Velena, AH; Vitolina, RO; Zarinsh, GV | 1 |
| Elliott, HL; Pasanisi, F; Reid, JL | 1 |
| Adam, LP; Henderson, EG | 1 |
| Karasawa, A; Kubo, K; Nakamizo, N; Oka, T; Shuto, K | 2 |
| Barbieri, L; Camerini, F; Mestroni, L | 1 |
| Bagatin, J; Drinovec, J; Marinković, M; Nesović, M; Nikodijević, B; Rumboldt, Z; Srbinovski, M; Stalc, A; Stojanova, D | 1 |
| Calder, AA; Forbes, CD; Greer, IA; McLaren, M; Walker, JJ | 1 |
| Namiki, A; Nishikawa, T; Omote, K; Takahashi, T | 1 |
| Bonandi, L; Dei Cas, L; Feroldi, P; Metra, M; Nodari, S; Nordio, G; Raddino, R; Visioli, O | 1 |
| Baky, S; Nademanee, K; Singh, BN | 1 |
| Ito, H; Mori, S; Yamamoto, K | 1 |
| Ishii, A; Nakamizo, N; Nishida, K; Oka, T | 1 |
| Karasawa, A; Kubo, K; Nakamizo, N; Oka, T | 1 |
| Ikeda, J; Karasawa, A; Kubo, K; Nakamizo, N; Oka, T; Yamada, K | 1 |
| Adler, D; Benveniste, C; Dayer, P; Porchet, HC | 1 |
| Bernard, JM; Pinaud, M | 1 |
| Hirakawa, S; Ito, H; Kotoo, Y; Sahashi, T; Takai, K; Wada, H | 1 |
| Charnet, P; Nargeot, J; Ouadid, H; Richard, S; Tiaho, F | 1 |
| Collins, WC; Cullen, MJ; Feely, J | 1 |
| Allely, MC; Alps, BJ | 1 |
| Angignard, D; Cahn, J; Greiner, PO | 1 |
| Endou, K; Sato, T; Yamamoto, H | 1 |
| Armstrong, C; Blackwood, R; Garnham, J | 1 |
| Freslon, JL; Julou-Schaeffer, G | 1 |
| Charnet, P; Nargeot, J; Ouadid, H; Richard, S | 1 |
| Hayakawa, T; Kato, A; Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T | 1 |
| Hatae, J | 1 |
| Dang Tran, L; Gaillard, G; Montastruc, JL; Montastruc, P; Valet, P | 1 |
| McCredie, M; McGill, D; McKenzie, W | 1 |
| Bowles, MJ; Khurmi, NS; O'Hara, MJ; Raftery, EB | 1 |
| Coxhead, PF; Douglas-Jones, AP | 1 |
| Ishihara, H; Kotani, N; Kudo, M; Matsuki, A; Oyama, T; Sakai, T; Tanioka, F | 1 |
| Kuramoto, K; Miyashita, H; Yamada, K | 1 |
| Ishii, S; Miyazaki, M; Mori, K; Okumura, F; Yoshiya, I | 1 |
| Enomoto, H; Ishii, S; Miyazaki, M; Mori, K; Okumura, F; Sumioka, T; Taguchi, H; Tamai, S; Uchida, M; Yoshiya, I | 1 |
| Ito, K; Kawazoe, T; Mizuguchi, T; Momose, T; Murakami, M; Takazawa, T; Takeya, H; Yamada, M; Yamazaki, Y; Yogozawa, T | 1 |
| Pruneau, D; Roy, F | 1 |
| Colnago, R; Fiorella, G; Guffanti, E; Mazzola, C; Scarpazza, P; Turri, DR; Vaccarella, A | 1 |
| Hanet, C; Pardonge-Lavenne, E; Pouleur, H; Rousseau, MF; Van den Berghe, G; Van Hoof, F | 1 |
| Arai, T; Hatano, Y; Ishida, H; Mori, K | 1 |
| Finlayson, JR; Frais, MA; Graham, DJ; Reynolds, G; Silke, B; Taylor, SH; Verma, SP | 1 |
| Shimizu, Y | 1 |
| Bermejo, F; Calandre, L; del Ser, T; Gomara, S | 1 |
| Alexander, O; Cairncross, L; Dow, RJ; Graham, DJ; Hall, DJ; Rush, WR | 1 |
| Caruana, MP; Kohli, RS; Lahiri, A; Raftery, EB; Robinson, CW | 1 |
| Balasch, J; Grau, M; Montero, JL | 1 |
| Jayakody, RL; Kappagoda, CT; Senaratne, MP | 1 |
| Fujihira, T; Fukuchi, Y; Imaizumi, T; Ishii, N; Kuroiwa, A; Miyahara, K; Nakashima, Y; Takasugi, M | 1 |
| Endo, T; Fujita, S; Hayakawa, H; Iida, N; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H | 1 |
| Acerbi, D; Bongrani, S; Ciampalini, G; Ferrari, R; Schiantarelli, P | 1 |
| Evans, TR; Greenbaum, RA; Wan, S | 1 |
| Fukui, S; Fukusaki, M; Gotoh, Y; Haseba, S; Miyako, M | 1 |
| Ishihara, H; Kudoh, M; Matsuki, A; Oyama, T; Suzuki, T; Tanioka, F; Yamashita, M | 1 |
| Baba, S | 1 |
| Cody, RJ; Kubo, SH; Lystash, J; Ryman, KS; Stone, G | 1 |
| Kondo, M; Miyamura, K; Moriyama, Y; Nanjo, K; Nishi, M; Sanke, T | 1 |
| Kawada, M; Satoh, K; Taira, N; Wada, Y | 1 |
| Hafizullah, M; Hussain, M; Jackson, NC; Reynolds, G; Silke, B; Taylor, SH; Verma, SP | 1 |
| Henry, PD | 1 |
| Asplund, J | 1 |
| Bellet, M; Bouchacourt, P; Forette, F; Guerret, M; Henry, JF; Hervy, MP; Poyard-Salmeron, C | 1 |
| Frais, MA; Jackson, N; Lee, P; Silke, B; Taylor, SH; Verma, SP | 1 |
| Gelman, JS; Pepine, CJ | 1 |
| Bolli, P; Bühler, FR; Hulthén, UL | 2 |
| Baty, J; Dow, RJ; Isles, TE | 2 |
| Geyskes, GG; Hene, RJ; van Schaik, BA | 1 |
| Littler, WA; Stallard, TJ; Watson, RD; Young, MA | 1 |
| Biggi, A; Coruzzi, P; Musiari, L; Novarini, A; Ravanetti, C | 1 |
| Feldman, RL; Gelman, JS; Pepine, CJ; Scott, E | 1 |
| Hidaka, H; Inagaki, M; Sasaki, Y; Tanaka, T | 1 |
| Freedman, D; Hermanovich, J; Lewinter, MM; Scheidt, S; Venkataraman, K | 1 |
| Freedman, D; Gheorghiade, M; Schwemer, G; St Clair, C; St Clair, J | 1 |
| Grier, CE; Mastro, AM | 1 |
| Bellet, M; Chaignon, M; Guédon, J; Lucsko, M; Rapoud, C | 1 |
| Gauville, C; Marre, M; Passa, P | 1 |
| Frais, MA; Jackson, N; Lee, P; Reynolds, G; Silke, B; Taylor, SH; Verma, SP | 1 |
| Borgers, M; Donck, LV; Pauwels, PJ; Vandeplassche, G | 1 |
| Baba, T; Boku, A; Ishizaki, T; Sone, K; Takebe, K | 1 |
| Feldman, RL; Hill, JA; Lambert, CR; Pepine, CJ | 2 |
| Bajka, E; Benjamin, E; Visor, GC | 1 |
| Holbrook, RH; Katz, M; Lirette, M | 1 |
| Feldman, RL; Hill, JA; Lambert, CR; Nichols, WW; Pepine, CJ | 1 |
| Ezaki, T; Miyagi, N; Nakatani, K; Sakamoto, K; Sugizaki, T | 1 |
| Asano, T; Hidaka, H | 1 |
| Kai, H; Matsuoka, H; Matsuura, H; Sugimachi, K; Ueo, H | 1 |
| Bongrani, S; Razzetti, R; Schiantarelli, P | 2 |
| Ishii, K; Kato, H; Kurihara, J; Miyajima, Y; Nakayama, K | 1 |
| Fujii, K; Inoue, R; Yamanaka, K; Yoshitomi, T | 1 |
| Aikawa, K; Fujikura, M; Gomi, T; Hirao, A; Kobayashi, M; Okumura, M; Ozeki, M; Tateishi, T; Yamamoto, H; Yumoto, S | 1 |
| Bouthier, J; Levenson, J; Maarek, BC; Safar, ME; Simon, AC | 1 |
| Littler, WA; Young, MA | 1 |
| Kolloch, R; Overlack, A; Stumpe, KO | 1 |
| Jaarsma, W; Kan, G; Koolen, JJ; Lie, KI; Visser, CA | 1 |
| McCredie, RM; McGill, DA; McKenzie, WB | 1 |
| Alexander, OF; Dow, RJ; Freedman, D; Graham, DJ; Hall, DJ; Mroszczak, EJ | 1 |
| Alps, BJ; Calder, C; Wilson, A | 2 |
| Campbell, BC; Hillis, WS; Kelman, AW | 1 |
| Czech, T; Gaab, MR; Korn, A | 1 |
| Asano, M; Inagaki, O; Shibasaki, M; Shiono, K; Takenaka, T | 1 |
| Fukui, A; Fukutomi, O; Kinoshita, H; Ohsumi, A; Sakai, T; Takaori, M; Yano, H; Yoshida, H | 1 |
| Fujimura, M; Ishizaki, T; Kanamori, K; Koshino, T; Matsuda, T; Minami, S; Miyabo, S; Nishioka, S; Okafuji, K; Saga, T | 1 |
| Hamaji, M; Kawamori, R; Kawashima, Y; Mashimo, T; Miyata, M; Nakao, K; Shichiri, M | 1 |
| Alaimo, A; Cascone, A; Cascone, G; Daprati, A; Ferrari, F | 1 |
| Kawashima, I; Nakayama, S; Ohba, T; Sakamoto, K; Tonooka, M; Yasuhara, H | 1 |
| Kaba, K; Matsumoto, T; Morimura, T; Tani, E | 1 |
| Khmel'-Dunaĭ, GN; Narushiavichus, EV | 1 |
| Gascón Ramón, G | 1 |
| McClelland, DL; Rosenkranz, RP; Roszkowski, AP | 2 |
| Frais, MA; Jackson, N; Reynolds, G; Silke, B; Taylor, SH; Verma, SP | 1 |
| Clark, JS; Jubb, SN; Maloney, PJ; Young, JM | 1 |
| Noshiro, O; Ohhata, I; Ohta, A; Shikama, H | 1 |
| Hagiwara, Y; Hara, T; Hirashima, T; Kokumi, N; Oomiya, A | 1 |
| Iijima, T; Taira, N; Yanagisawa, T | 1 |
| Groth, H; Locher, R; Neyses, L; Stimpel, M; Vetter, W | 1 |
| Kass, RS; Sanguinetti, MC | 1 |
| Woodson, LC; Ziegler, MG | 1 |
| Kou, K; Suzuki, H | 1 |
| Bolger, GT; Gengo, P; Jim, K; Siegel, H; Triggle, DJ | 1 |
| Chen, YH; Duan, MJ; Liu, XM; Su, ML; Wei, JY | 1 |
| Endoh, M; Taira, N; Yanagisawa, T | 1 |
| Maeno, H; Nishikori, K; Takenaka, T | 1 |
| Andrenyak, DM; Epstein, PM; Fiss, K; Hachisu, R | 1 |
| Fujiwara, S; Kuriyama, H | 1 |
| Kajiwara, A; Ohizumi, Y; Yasumoto, T | 1 |
| Lagercrantz, C; Larsson, T; Lincoln, P; Sörskog, L | 1 |
| Bristow, MR; Ginsburg, R; Laser, JA; McAuley, BJ; Minobe, W | 1 |
| Ogura, A; Takahashi, M | 2 |
| Carver, LA; Lee, CH; Strosberg, AM | 1 |
| Ishibashi, F; Kubo, K | 1 |
| Bolli, P; Bühler, FR; Erne, P; Kiowski, W; Müller, FB | 1 |
| Bala Subramanian, V; Bowles, MJ; Khurmi, NS; Raftery, EB | 1 |
| Abrile, PG; Boero, E; Castrignano, A; Livi, A; Maffei, P; Magaia, O; Mocini, A; Perugini, P; Seu, V | 1 |
| Duhaze, P; Giudicelli, JF; Gueret, M; Kiechel, JR; Lhoste, F; Thuillez, C | 1 |
| Hulthén, UL | 1 |
| Advenier, C; Cerrina, J; Duroux, P; Floch, A; Pradel, J; Renier, A | 1 |
| Chang, WC; Ito, H; Murota, S; Nakao, J; Ooyama, T | 1 |
| Fujita, T; Noda, H | 1 |
| Kawakami, S; Murakami, T; Senoo, Y; Teramoto, S | 1 |
| Bellet, M; Bouchacourt, P; Forette, F; Henry, JF; Hervy, MP; Poyard-Salmeron, C | 1 |
| Freslon, JL; Giudicelli, JF; Richer, C | 1 |
| Maeno, H; Nagano, K; Ohata, I; Sakamoto, N | 1 |
| Furuya, H; Kishi, Y; Okumura, F | 1 |
| Miura, K; Sakata, S | 1 |
| Kashimoto, T; Ohtsubo, N; Shimizu, C; Tachikawa, E; Takahashi, E; Takahashi, S | 1 |
| Abe, M; Kato, M; Kawamura, A; Koeda, T; Orikasa, C; Takahashi, H; Usui, Y | 1 |
| Asai, K; Kuzuya, F; Naito, M; Shibata, K; Yoshimine, N | 1 |
| Bassein, L; Coluccini, M; Di Pasquale, G; Dominici, P; Lusa, AM; Manini, GL; Pinelli, G | 1 |
| Kushinsky, S; Massey, IJ; Wu, AT | 1 |
| Charlier, AA; Pouleur, H; Rousseau, MF; Van den Berghe, G; Van Hoof, F; Vincent, MF | 1 |
| Hussain, M; Nelson, GI; Silke, B; Taylor, SH; Verma, SP | 1 |
| Chiba, S; Furukawa, Y; Kobayashi, M; Saegusa, K; Shimotori, M | 1 |
| Arimitsu, T; Mori, K; Oda, Y; Okumura, T | 1 |
| Bassein, L; Coluccini, M; Di Pasquale, G; Lusa, AM; Manini, GL; Pinelli, G | 1 |
| Lefer, AM; Leprán, I; Roth, DM; Smith, JB | 1 |
| Miyamura, K; Nasu, M; Sakai, T; Shikano, K; Shomura, S | 1 |
| Hafizullah, M; Jackson, NC; Reynolds, G; Silke, B; Taylor, SH; Verma, SP | 1 |
| Jaarsma, W; Kan, G; Lie, KI; Visser, CA | 1 |
| Lipkin, D; Poole-Wilson, PA | 1 |
| Brasseur, LA; Charlier, AA; Etienne, J; Pouleur, H; Rousseau, MF; Van Eyll, C; Van Mechelen, H | 1 |
| Frais, MA; Hafizullah, M; Jackson, NC; Reynolds, G; Silke, B; Taylor, SH; Verma, SP | 1 |
| Caruana, MP; Harlow, BJ; Kohli, RS; Lahiri, A; Raftery, EB; Robinson, CW; Tovey, J | 1 |
| Dow, RJ; Freedman, D; Graham, DJ; Ling, T; Mroszczak, E | 1 |
| Itaya, Y; Kondo, K; Saruta, T; Suzuki, H | 1 |
| Handa, J; Kidooka, M; Matsuda, M; Nakasu, S; Nakasu, Y; Watanabe, K | 1 |
| Akazawa, S; Futatsuki, K; Honda, T; Sampi, K | 1 |
| Andersson, KE; Forman, A; Maigaard, S; Ulmsten, U | 1 |
| Nakamura, O; Nomura, K; Shibui, S; Watanabe, T | 1 |
| Advenier, C; Cerrina, J; Duroux, P; Floch, A; Renier, A | 1 |
| Tsuruo, T | 1 |
| Bellinetto, A; Lessem, J | 1 |
| Araki, S; Hirata, A; Hokamura, Y; Horio, Y; Kimura, Y; Matsuyama, K; Okumura, K; Ono, T; Rokutanda, M; Takaoka, K | 1 |
| Hattori, M; Honda, T; Sampi, K | 1 |
| Ahuja, RC; Nelson, GI; Okoli, RC; Silke, B; Taylor, SH | 1 |
| Bando, S; Kakutani, A; Minezono, K; Mori, H; Noda, T; Shinomiya, H | 1 |
| Amano, J; Okamura, T; Sunamori, M; Suzuki, A | 1 |
| Hornung, RS; Jones, RI; Raftery, EB; Sonecha, T | 1 |
| Alps, BJ; Calder, C; Scott-Park, FM; Wilson, A | 1 |
| Littler, WA; Watson, RD; Young, MA | 1 |
| Charlier, AA; Pouleur, H; Rousseau, MF; van Eyll, C | 1 |
| Kaburagi, T; Yokoyama, S | 2 |
| Koshino, T | 1 |
| Geyskes, GG; van Nistelrooy, AE; van Schaik, BA | 1 |
| Arai, S; Hattori, N; Maekawa, M; Nomura, G; Ohta, H; Takabatake, T; Yamamoto, Y | 1 |
| Becker, HJ; Dowinsky, S; Hopf, R; Kaltenbach, M; Kober, G | 1 |
| Ishii, K; Kato, H; Nakayama, K | 1 |
| Hof, RP | 1 |
| Iliopoulou, A; Turner, P; Warrington, SJ | 1 |
| Kadoya, M; Kawai, C; Konishi, T; Matsuda, H; Tamamura, T; Yokoyama, S | 1 |
| Bolger, GT; Triggle, CR; Triggle, DJ | 1 |
| Goto, Y; Hamada, M; Kai, Y; Toyota, T; Umezu, M | 1 |
| Csapo, AI; Henzl, MR; Puri, CP; Tarro, S | 1 |
| Bala Subramanian, V | 1 |
| Asano, M; Higuchi, S; Maeno, H; Miyazaki, I; Takenaka, T | 1 |
| Kanno, M; Nakaya, H | 1 |
| Higuchi, S; Shiobara, Y | 3 |
| Maeno, H; Takenaka, T; Terai, M | 1 |
| Higuchi, S; Kawamura, S | 1 |
| Chiba, S; Furukawa, Y; Iwatsuki, K; Watanabe, H | 1 |
| Chapunoff, D; Herman, CA; Romero, MA; Schulmeister, K; Skarda, S; Torres, OA | 1 |
| Deguchi, T; Hara, T; Hattori, O; Kato, Y; Saijyo, T; Suzuki, K; Tanaka, H | 1 |
| Hosoi, K; Kamioka, H; Kawata, T; Miki, Y; Sumitani, K; Tagami, K; Terai, K | 1 |
| Fukata, F; Kanda, M; Kurahashi, K; Matsui, H; Nakamura, S; Shirahase, H; Wada, K | 1 |
| Fukuya, F; Hosoki, K; Ikeno, A; Karasawa, T; Minato, H; Nose, I; Takeyama, K | 1 |
| Arimura, T; Kobayashi, K; Okada, T; Piccolino, M; Tachibana, M | 1 |
| Dupont, AG; Massart, DL; Schoors, DF; Vercruysse, I | 1 |
| Maddalena, F; Rocco, CG; Villanova, C | 1 |
| Bretnall, AE; Clarke, GS | 1 |
| Hibi, M; Iwase, J; Kawamura, M; Murakami, F; Usui, A; Yoshida, K | 1 |
| Mak, IT; Weglicki, WB | 1 |
| Allain, H; Bentue-Ferrer, D; Milon, D; Rault, B; Saïag, B; Van den Driessche, J | 1 |
| Borow, KM; Ehler, D; Friday, K; Lang, RM; Murphy, M; Neumann, A; Valentine-Bates, B; Wolff, A | 1 |
| Hongo, K; Kobayashi, S | 1 |
| Sanada, H | 1 |
| Dubray, C; Francheteau, P; Guerret, M; Merdjan, H; Steimer, JL | 1 |
| Hashimoto, H; Kuriyama, Y; Nagatsuka, K; Omae, T; Sawada, T | 1 |
| Edamatsu, R; Hiramatsu, M; Mori, A; Mori, I; Ohba, S | 1 |
| Advenier, C; Brisac, AM; Cortijo, J; Laurent, S; Naline, E; Sarriá, B; Zhang, Y | 1 |
| Inoue, H; Minami, T; Ogawa, J; Shohtsu, A | 1 |
| Akasu, T; Krier, J; Nishimura, T | 1 |
| Karasawa, A; Kubo, K; Shirakura, S | 1 |
| Hashimoto, Y; Hirota, K; Ishihara, H; Koh, H; Matsuki, A; Takagi, H | 1 |
| Newsholme, P; Otoole, CE | 1 |
| Balakumaran, A; Campbell, GA; Moslen, MT | 1 |
| Morgan, EH; Savigni, DL | 1 |
| Dozen, M; Hayashi, Y; Hosono, M; Watanabe, K | 1 |
| Kanno, Y; Okada, H; Saruta, T; Suzuki, H; Takenaka, T | 1 |
| Borowicz, K; Czuczwar, SJ; Gasior, M; Kleinrok, Z; Starownik, R | 2 |
| Kikuchi, K; Sugawara, H; Tobise, K | 1 |
| Akimoto, K; Jareonkitmongkol, S; Kawashima, H; Shimizu, S; Shirasaka, N | 1 |
| Akopov, SE; Kazarian, AV; Simonian, NA | 1 |
| Akaike, N; Ishibashi, H; Rhee, JS | 1 |
| Dailly, E; Jolliet, P; Simon, N; Tillement, JP; Urien, S | 1 |
| Shimada, H; Sugino, H | 1 |
| Deng, J; Shi, Y; Shu, C; Yin, J | 1 |
| White, CM | 1 |
| Cohen, C; Perrault, G; Sanger, DJ | 1 |
| Deng, J; Shi, Y; Yin, J | 1 |
| Hori, Y; Matsumiya, T; Takeda, H; Tsuji, M | 1 |
| Hayasaka, S; Hiraki, S; Zhang, XY | 1 |
| Seibold, JR; Sturgill, MG | 1 |
| Ban, Y; Makita, T | 1 |
| Ito, Y; Ogino, K; Takagi, K; Takemoto, M; Tomita, T | 1 |
| Ogino, K; Pang, YW; Tomita, T | 1 |
| Fujii, Y; Kamibayashi, M; Miyazaki, H; Nagashima, K; Nomura, Y; Okuma, Y; Shimizu, K; Tanaka, S; Uehara, T | 1 |
| Gao, X; Gillman, MW; Goldman, L; Hertzmark, E; McLaughlin, TJ; Ross-Degnan, D; Soumerai, SB; Spiegelman, D | 1 |
| Bisenieks, E; Briede, J; Daija, D; Duburs, G; Makarova, N; Poikans, J; Uldriķis, J | 1 |
| Andreas, K; Bräter, M; Li, SN | 1 |
| Anderson, A; Edwards, RJ; Kim, H; Okita, JR; Okita, RT; Springer, DL; Thomas, PE; Zangar, RC | 1 |
| Asakura, Y; Asano, M; Goto, A; Iwasawa, K; Morita, T; Nakajima, T; Nakamura, F; Okuda, Y; Soma, M; Suzuki, S; Tomaru, T; Toyo-oka, T; Wang, Y | 1 |
| He, GW; Yang, CQ | 1 |
| Matsuda, Y; Tsukuda, E | 1 |
| Hara, I; Taya, K; Watanabe, Y; Zhang, J | 1 |
| Fujita, T; Kamiya, H; Nakayama, Y; Shimohigashi, Y; Takano, Y; Tanabe, S; Tsujimoto, G | 1 |
| Sekiguchi, F; Shimamura, K; Sunano, S; Yamamoto, K | 1 |
| Aono, Y; Ariyoshi, H; Kawasaki, T; Monden, M; Sakon, M; Tsuji, Y; Ueda, A | 1 |
| Marik, PE; Varon, J | 1 |
| Fujimori, Y; Kamisaki, Y; Maeda, S; Morisaki, I; Saeki, M | 1 |
| Kuo, SM; Lin, CP; Morehouse, HF | 1 |
| Daniels, SR; Sinaiko, AR | 1 |
| Cathala, L; Chesnoy-Marchais, D | 1 |
| Canver, CC; Chanda, J | 1 |
| Aminabhavi, TM; Kulkarni, AR; Soppimath, KS | 1 |
| Mak, IT; Weglicki, WB; Zhang, J | 1 |
| Akimoto, Y; Fujii, A; Matsumoto, H; Noji, I | 1 |
| Chang, HT; Chen, WC; Huang, JK; Jan, CR; Jiann, BP; Lu, YC; Su, W; Yu, CC | 1 |
| Arakawa, N; Hiramori, K; Nagano, M; Naganuma, Y; Nakamura, M; Yoshida, H | 1 |
| Hobara, N; Hokama, N; Kameya, H; Ohshiro, S; Sakai, M; Sakanashi, M | 1 |
| Craig, AG; Saccone, GT; Toouli, J; Tottrup, A | 1 |
| Hashiba, E; Hirota, K; Kabara, S; Matsuki, A; Yoshioka, H | 1 |
| Miller, SM; Szurszewski, JH | 1 |
| Pope, J | 4 |
| Dezawa, M; Ishikawa, F; Ishikawa, H; Mamiya, K; Metoki, T; Nakazawa, M; Ohguro, H; Ohguro, I; Takano, Y; Yamazaki, H | 1 |
| Iida, H; Iwasawa, K; Jo, T; Ma, J; Nagai, R; Nakajima, T; Omata, M | 1 |
| Abe-Dohmae, S; Arakawa, R; Inoue, K; Nishimaki-Mogami, T; Suzuki, S; Tamehiro, N; Tanaka, AR; Ueda, K; Yokoyama, S | 1 |
| Degawa, M; Konno, Y; Nemoto, K; Sekimoto, M | 2 |
| Cabrol, D; Carbonne, B; Tsatsaris, V | 1 |
| Hiroshi, N; Katoh, H; Okada, Y; Sakamoto, T; Shima, K; Tuzuki, N; Yanagawa, Y | 1 |
| Carbonne, B; Dekker, GA; Flenady, VJ; King, JF; Papatsonis, DN | 1 |
| Carbonne, B | 1 |
| Ambudkar, SV; Bates, SE; Robey, RW; Shukla, S | 1 |
| Frishman, WH; Schlocker, SJ; Tejani, N; Veresh, M | 1 |
| Sahney, S | 1 |
| Clark, J; Cull, A; Klose, MK; Mercier, AJ; Milakovic, M | 1 |
| Basso, A; Cioli, D; Festucci, A; Guidi, A; Liberti, P; Marcatto-Maggi, AL; Nobre-Santana, S; Orsini, T; Pica-Mattoccia, L; Troiani, AR; Valle, C | 1 |
| Bazin, JE; Bolandard, F; Chanséaume, S; Constantin, JM; Gallot, D; Perbet, S; Vignaud, M; Zénut, M | 1 |
| Baldwin, K; McCoy, S | 1 |
| Cabrol, D; Carbonne, B; Goffinet, F; Le Ray, C; Maillard, F; Verspyck, E | 1 |
| An Haack, K; Bennett, MJ; Li, H; Narayan, SB; Tan, L; Warnock, A | 1 |
| Beutler, JJ; de Gooijer, A; Gaillard, CA; Kroon, AA; van den Born, BJ; van den Meiracker, AH | 1 |
| Deis, S; Haddad, B; Kayem, G; Laas, E | 1 |
| Anderson, ME; Ennis, H; Herrick, AL; Wilkinson, J | 1 |
| Daschil, N; Humpel, C | 1 |
| Bejan-Angoulvant, T; Crochet, J; Jonville-Bera, AP | 1 |
| Imai, H; Inano, A; Kataoka, M; Morimoto, T; Mutaguchi, K; Ohashi, K; Sugiyama, Y; Suzaki, Y; Togashi, K; Yamashita, S | 1 |
| Anderson, ME; Ennis, H; Herrick, AL; Hughes, M; Wilkinson, J | 1 |
| Ando, K; Cao, X; Izumi-Nakaseko, H; Nakamura, Y; Saitoh, M; Sugiyama, A; Takahara, A; Wada, T; Xu, B; Zhu, B | 1 |
| Alnajjar, LM; Bulatova, NR; Darwish, RM | 1 |
| Barth, M; Mäder, K; Zlomke, C | 1 |
25 review(s) available for nifedipine and nicardipine
| Article | Year |
|---|---|
New developments in Ca2+ channel antagonists.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Electrophysiology; Heart; Humans; Ion Channels; Muscle Relaxation; Muscle, Smooth; Potassium; Sodium; Structure-Activity Relationship; Substrate Specificity | 1983 |
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells | 2022 |
Antihypertensive therapy in the geriatric patient. I: A review of the role of calcium channel blockers.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hypertension; Middle Aged; Multicenter Studies as Topic; Nicardipine; Nifedipine; Random Allocation | 1989 |
Antihypertensive agents--the race for third place.
Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Diazoxide; Felodipine; Humans; Hydralazine; Indoramin; Labetalol; Minoxidil; Nicardipine; Nifedipine; Vasodilator Agents; Verapamil | 1985 |
[Calcium antagonists in congestive heart failure].
Topics: Calcium Channel Blockers; Cardiomyopathy, Dilated; Diltiazem; Felodipine; Heart Failure; Hemodynamics; Humans; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Verapamil | 1988 |
Second-generation calcium antagonists: search for greater selectivity and versatility.
Topics: Animals; Bepridil; Calcium Channel Blockers; Cinnarizine; Electrophysiology; Flunarizine; Heart; Humans; Lidoflazine; Muscle, Smooth, Vascular; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyrrolidines; Structure-Activity Relationship | 1985 |
Atherosclerosis, calcium, and calcium antagonists.
Topics: Animals; Aorta; Arteries; Arteriosclerosis; Calcinosis; Calcium; Calcium Channel Blockers; Cell Survival; Cholesterol, Dietary; Cinnarizine; Diltiazem; Flunarizine; Humans; Membrane Lipids; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Propranolol; Rabbits; Verapamil | 1985 |
Calcium entry blockers as vasodilators in man.
Topics: Calcium Channel Blockers; Humans; Hypertension; Nicardipine; Nifedipine; Nitroprusside; Vascular Resistance; Vasodilation; Verapamil | 1984 |
[Treatment of angina pectoris with calcium antagonists].
Topics: Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Therapy, Combination; Exercise Test; Fendiline; Humans; Nicardipine; Nifedipine; Perhexiline; Prenylamine; Propafenone; Propiophenones; Verapamil | 1982 |
Calcium antagonists for the treatment of vasospasm following subarachnoid haemorrhage.
Topics: Animals; Calcium Channel Blockers; Cerebrovascular Circulation; Diltiazem; Humans; Ischemic Attack, Transient; Nicardipine; Nifedipine; Nimodipine; Subarachnoid Hemorrhage | 1993 |
Calcium channel blockers in left ventricular dysfunction or congestive heart failure.
Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Felodipine; Heart Failure; Humans; Nicardipine; Nifedipine; Ventricular Dysfunction, Left; Verapamil | 1997 |
The diagnosis and management of hypertensive crises.
Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Clonidine; Diazoxide; Enalaprilat; Female; Fenoldopam; Humans; Hypertension; Labetalol; Nicardipine; Nifedipine; Nitroprusside; Phentolamine; Pre-Eclampsia; Pregnancy; Propanolamines; Trimethaphan | 2000 |
Raynaud's phenomenon (primary).
Topics: Amlodipine; Diltiazem; Humans; Nafronyl; Nicardipine; Nifedipine; Raynaud Disease; Vasodilator Agents | 2003 |
Pharmacokinetics of tocolytic agents.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Female; Humans; Magnesium Sulfate; Myometrium; Nicardipine; Nifedipine; Oxytocics; Pregnancy; Tocolytic Agents | 2004 |
Raynaud's (primary).
Topics: Humans; Nicardipine; Nifedipine; Raynaud Disease; Vasodilator Agents | 2003 |
Raynaud's phenomenon (primary).
Topics: Humans; Nicardipine; Nifedipine; Raynaud Disease; Vasodilator Agents | 2004 |
Raynaud's phenomenon (primary).
Topics: Humans; Nicardipine; Nifedipine; Raynaud Disease; Vasodilator Agents | 2005 |
Pathophysiology and medical management of systemic hypertension in preeclampsia.
Topics: Adrenergic beta-Antagonists; Aspirin; Calcium; Calcium Channel Blockers; Cerebral Hemorrhage; Female; Glomerular Filtration Rate; Humans; Hypertension; Ischemia; Labetalol; Liver; Nicardipine; Nifedipine; Placenta; Platelet Aggregation Inhibitors; Pre-Eclampsia; Pregnancy; Prostaglandins; Stroke | 2006 |
A review of calcium channel antagonists in the treatment of pediatric hypertension.
Topics: Amiodarone; Calcium Channel Blockers; Child; Felodipine; Humans; Hypertension; Isradipine; Nicardipine; Nifedipine; Verapamil | 2006 |
Pharmacotherapeutic options for the treatment of preeclampsia.
Topics: Female; Humans; Hydralazine; Magnesium Sulfate; Nicardipine; Nifedipine; Nitroprusside; Pre-Eclampsia; Pregnancy; Risk Factors | 2009 |
Calcium channel blockers for primary Raynaud's phenomenon.
Topics: Calcium Channel Blockers; Humans; Nicardipine; Nifedipine; Randomized Controlled Trials as Topic; Raynaud Disease | 2014 |
[Calcium channel blockers pharmacology and their use as tocolytics].
Topics: Adult; Calcium Channel Blockers; Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolytic Agents | 2015 |
Calcium channel blockers for primary Raynaud's phenomenon.
Topics: Calcium Channel Blockers; Humans; Nicardipine; Nifedipine; Randomized Controlled Trials as Topic; Raynaud Disease | 2016 |
59 trial(s) available for nifedipine and nicardipine
| Article | Year |
|---|---|
[Comparison of nicardipine and nifedipine in treatment of Chinese senile hypertension placebo-control, double-blind, randomized and crossover study].
Topics: Aged; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine | 1992 |
Serum concentration-effect relationship of (+/-)-nicardipine and nifedipine in elderly hypertensive patients.
Topics: Aged; Aged, 80 and over; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Nicardipine; Nifedipine; Single-Blind Method | 1992 |
Comparison of the cardiovascular effects of nifedipine and nicardipine in the presence of atenolol.
Topics: Administration, Oral; Adult; Atenolol; Blood Pressure; Double-Blind Method; Drug Interactions; Exercise Test; Heart Rate; Hemodynamics; Humans; Male; Nicardipine; Nifedipine; Stroke Volume | 1991 |
Nicardipine and nifedipine in the treatment of essential arterial hypertension.
Topics: Adult; Blood Pressure; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Pulse | 1991 |
Double-blind, randomized comparative study of the antihypertensive effect of nicardipine slow-release and nifedipine slow-release in hypertensive patients with coronary heart disease.
Topics: Blood Pressure Monitors; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Nicardipine; Nifedipine | 1991 |
Update of effects of calcium antagonists in myocardial infarction or angina in light of the second Danish Verapamil Infarction Trial (DAVIT-II) and other recent studies.
Topics: Angina, Unstable; Calcium Channel Blockers; Denmark; Humans; Myocardial Infarction; Nicardipine; Nifedipine; Verapamil | 1991 |
Treatment of hypertensive urgencies with oral nifedipine, nicardipine, and captopril.
Topics: Administration, Sublingual; Blood Pressure; Captopril; Emergencies; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Time Factors | 1991 |
[The comparative efficacy of nicardipine and nifedipine in stenocardia patients].
Topics: Angina Pectoris; Chronic Disease; Coronary Disease; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Physical Exertion; Placebos; Time Factors | 1990 |
Serum concentrations and effects of (+/-)-nicardipine compared with nifedipine in a population of healthy subjects.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Kinetics; Male; Nicardipine; Nifedipine; Polymorphism, Genetic; Randomized Controlled Trials as Topic; Reference Values; Single-Blind Method | 1990 |
The cardiovascular effects of oral nifedipine and nicardipine: a double-blind comparison in healthy volunteers using transthoracic bioimpedance cardiography.
Topics: Administration, Oral; Adult; Blood Pressure; Cardiac Output; Cardiography, Impedance; Double-Blind Method; Humans; Male; Nicardipine; Nifedipine; Physical Exertion; Stroke Volume | 1990 |
[Blood pressure monitoring in aged hypertensive patients treated with sustained-release nicardipine or nifedipine].
Topics: Aged; Aged, 80 and over; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Nicardipine; Nifedipine | 1990 |
Randomized double-blind comparison of side effects of nicardipine and nifedipine in angina pectoris. The Nicardipine Investigators Group.
Topics: Adult; Angina Pectoris; Dizziness; Double-Blind Method; Edema; Flushing; Foot Diseases; Headache; Humans; Multicenter Studies as Topic; Nicardipine; Nifedipine; Prospective Studies; Pulse; Randomized Controlled Trials as Topic | 1990 |
Comparison of the antianginal efficacy of four calcium antagonists and propranolol in stable angina pectoris.
Topics: Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Exercise Test; Female; Humans; Male; Nicardipine; Nifedipine; Nitroglycerin; Propranolol; Single-Blind Method; Verapamil | 1989 |
Comparison of the anti-anginal efficacy of nicardipine and nifedipine in patients receiving atenolol: a randomized, double-blind, crossover study.
Topics: Angina Pectoris; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Random Allocation | 1989 |
Antihypertensive therapy in the geriatric patient. I: A review of the role of calcium channel blockers.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hypertension; Middle Aged; Multicenter Studies as Topic; Nicardipine; Nifedipine; Random Allocation | 1989 |
Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease.
Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiazem; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Nisoldipine; Prospective Studies; Random Allocation; Verapamil | 1987 |
[Effects of chronic administration of several calcium antagonists on pituitary release of TSH].
Topics: Adult; Atenolol; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Pituitary Gland, Anterior; Random Allocation; Thyrotropin; Time Factors; Verapamil | 1987 |
Nicardipine versus nifedipine: multicentre controlled trial in essential hypertension.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Longitudinal Studies; Male; Middle Aged; Multicenter Studies as Topic; Nicardipine; Nifedipine; Pulse; Tablets | 1988 |
The effects of nicardipine on cerebrospinal fluid pressure in humans.
Topics: Adult; Aged; Anesthesia, Spinal; Blood Pressure; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Evaluation; Female; Heart Rate; Humans; Injections, Intravenous; Intracranial Pressure; Male; Middle Aged; Nicardipine; Nifedipine; Oxygen; Random Allocation | 1986 |
A randomized double-blind crossover study of nicardipine and nifedipine in patients with angina pectoris and concomitant essential hypertension.
Topics: Adult; Angina Pectoris; Blood Pressure; Double-Blind Method; Heart; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Nitroglycerin | 1988 |
[Absence of polymorphism in individual response to the dihydropyridines nifedipine and (+/-)-nicardipine].
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Male; Nicardipine; Nifedipine; Polymorphism, Genetic; Random Allocation; Time Factors | 1988 |
Calcium channel blocker drugs and diabetic control.
Topics: Adult; Aged; Blood Glucose; Calcium Channel Blockers; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Male; Middle Aged; Nicardipine; Nifedipine; Random Allocation | 1987 |
Comparison of the efficacy of nicardipine, a new calcium channel blocker, with nifedipine in the treatment of mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Body Weight; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Posture; Random Allocation | 1987 |
Comparison of nicardipine and propranolol for chronic stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Dyspnea; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Propranolol; Random Allocation | 1986 |
Randomized double-blind placebo-controlled comparison of nicardipine and nifedipine in patients with chronic stable angina pectoris.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Random Allocation | 1986 |
A general practice trial of antihypertensive therapy comparing a combination of nicardipine and chlorthalidone with atenolol and chlorthalidone.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Chlorthalidone; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Middle Aged; Nicardipine; Nifedipine | 1986 |
[Age and efficacy of calcium entry blocker in essential hypertension--double blind trial using nicardipine].
Topics: Adult; Age Factors; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Trichlormethiazide | 1986 |
[Antihypertensive effects of nicardipine hydrochloride (YC-93) on patients with hypertension during neuroleptanesthesia].
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hypertension; Intraoperative Complications; Male; Middle Aged; Neuroleptanalgesia; Nicardipine; Nifedipine | 1986 |
[A comparison between nicardipine hydrochloride (YC-93) and trimethaphan camsylate for treatment of acute hypertension during surgery. A double blind study in 12 institutions].
Topics: Acute Disease; Adolescent; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Intraoperative Complications; Middle Aged; Neuroleptanalgesia; Nicardipine; Nifedipine; Trimethaphan | 1986 |
[Result of randomized comparative clinical study of nicardipine hydrochloride and trimethaphan camsylate on control of blood pressure during surgery].
Topics: Aged; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hypertension; Intraoperative Complications; Male; Middle Aged; Neuroleptanalgesia; Nicardipine; Nifedipine; Random Allocation; Trimethaphan | 1986 |
Comparative haemodynamic effects of nicardipine and verapamil in coronary artery disease.
Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Artery Bypass; Exercise Test; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Verapamil | 1985 |
Nicardipine hydrochloride in essential hypertension--a controlled study.
Topics: Adult; Age Factors; Calcium Channel Blockers; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Renin | 1985 |
Effect of nicardipine in elderly hypertensive patients.
Topics: Age Factors; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine | 1985 |
Anti-hypertensive dose-response effects of nicardipine in stable essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine | 1985 |
Prevention of vasospastic angina with nicardipine.
Topics: Angina Pectoris, Variant; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Nicardipine; Nifedipine | 1985 |
The effect of nicardipine on glucose and drug-stimulated insulin secretion in normal volunteers.
Topics: Adult; Blood Glucose; C-Peptide; Calcium Channel Blockers; Glucose; Humans; Insulin; Insulin Secretion; Male; Nicardipine; Nifedipine; Tolbutamide | 1985 |
Nicardipine for angina pectoris at rest and coronary arterial spasm.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Vasospasm; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Nicardipine; Nifedipine; Nitroglycerin; Random Allocation; Rest; Vasodilator Agents | 1985 |
Nicardipine for stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Nitroglycerin | 1985 |
Short- and long-term treatment of stable effort angina with nicardipine, a new calcium channel blocker: a double-blind, placebo-controlled, randomised, repeated cross-over study.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Heart Rate; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Nitroglycerin; Physical Exertion; Random Allocation | 1985 |
The effect of nicardipine on pituitary hormone release in normal volunteers.
Topics: Adult; Calcium Channel Blockers; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Nicardipine; Nifedipine; Pituitary Hormones; Prolactin; Thyrotropin | 1985 |
Renal effects of nicardipine in patients with mild-to-moderate essential hypertension.
Topics: Adult; Calcium Channel Blockers; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney Function Tests; Male; Middle Aged; Nicardipine; Nifedipine; Random Allocation; Renal Circulation | 1986 |
Blood pressure, heart rate and A-V conduction responses to nicardipine in hypertensive patients receiving atenolol.
Topics: Adult; Atenolol; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Female; Heart Conduction System; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine | 1985 |
Noninvasive assessment of the haemodynamic effects of nicardipine in normotensive subjects.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Humans; Kinetics; Male; Nicardipine; Nifedipine; Systole | 1985 |
Haemodynamic analysis of the effects of nicardipine and metoprolol alone and in combination in coronary artery disease.
Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Nicardipine; Nifedipine | 1985 |
Short- and long-term efficacy of nicardipine, assessed by placebo-controlled single- and double-blind crossover trials in patients with chronic stable angina.
Topics: Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Nicardipine; Nifedipine | 1984 |
[Preliminary note on the use of calcium antagonists in ischemic cardiopathy].
Topics: Adult; Angina Pectoris; Benzazepines; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Female; Humans; Male; Middle Aged; Myocardial Infarction; Nicardipine; Nifedipine | 1984 |
Nicardipine: pharmacokinetics and effects on carotid and brachial blood flows in normal volunteers.
Topics: Adult; Aldosterone; Brachial Artery; Calcium Channel Blockers; Carotid Arteries; Epinephrine; Female; Humans; Kinetics; Male; Nicardipine; Nifedipine; Norepinephrine; Radioimmunoassay; Regional Blood Flow; Renin | 1984 |
[Treatment of arterial hypertension in the aged with a calcium antagonist: nicardipine].
Topics: Aged; Calcium Channel Blockers; Double-Blind Method; Drug Evaluation; Female; Humans; Hypertension; Hypotension, Orthostatic; Male; Middle Aged; Nicardipine; Nifedipine | 1984 |
Comparative efficacy of nicardipine, a new calcium antagonist, versus nifedipine in effort stable angina.
Topics: Aged; Angina Pectoris; Double-Blind Method; Drug Evaluation; Exercise Test; Female; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Physical Exertion | 1984 |
Comparative efficacy of nicardipine, a new calcium antagonist, versus nifedipine in stable effort angina.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Drug Administration Schedule; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Random Allocation; Rest | 1984 |
Haemodynamic effects of intravenous nicardipine during upright exercise in patients with stable angina pectoris.
Topics: Adult; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Physical Exertion; Vascular Resistance | 1984 |
Effect of nicardipine on myocardial contractility and on angina induced by atrial pacing in patients with coronary artery disease (abstract).
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiac Pacing, Artificial; Coronary Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Myocardial Contraction; Nicardipine; Nifedipine | 1984 |
Blockade of slow calcium channels and regulation of circulatory pressor responses in uncomplicated hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Vasoconstriction | 1983 |
Acute haemodynamic effects of a new calcium antagonist, nicardipine, in man. A comparison with nifedipine.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Heart Ventricles; Hemodynamics; Humans; Male; Nicardipine; Nifedipine; Placebos; Pyridines | 1983 |
[The efficacy and safety of slow-release nicardipine vs nifedipine in angina].
Topics: Adult; Aged; Angina, Unstable; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Time Factors | 1994 |
Noninvasive assessment of the direct action of oral nifedipine and nicardipine on left ventricular contractile state in patients with systemic hypertension: importance of reflex sympathetic responses.
Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Echocardiography, Doppler; Heart Ventricles; Hemodynamics; Humans; Hypertension; Middle Aged; Myocardial Contraction; Nicardipine; Nifedipine; Propanolamines; Reflex; Stimulation, Chemical; Sympathetic Nervous System; Ventricular Function, Left | 1993 |
Calcium channel blockers versus ACE inhibitors as antihypertensives in polycystic kidney disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Polycystic Kidney Diseases | 1996 |
Effects of nifedipine and nicardipine on regional cerebral blood flow distribution in patients with arterial hypertension.
Topics: Adult; Aged; Blood Pressure; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Circulation; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine | 1996 |
Nitric oxide plays an insignificant role in direct vasodilator effects of calcium channel blockers in healthy humans.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diltiazem; Endothelium, Vascular; Enzyme Inhibitors; Forearm; Heart Rate; Humans; Male; Nicardipine; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plethysmography; Vasodilation; Vasodilator Agents | 2002 |
354 other study(ies) available for nifedipine and nicardipine
| Article | Year |
|---|---|
Dihydropyrimidines: novel calcium antagonists with potent and long-lasting vasodilative and antihypertensive activity.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Dogs; Female; Heart Rate; Indicators and Reagents; Male; Molecular Structure; Pyrimidines; Rats; Rats, Inbred SHR; Receptors, Nicotinic; Structure-Activity Relationship; Vasodilator Agents | 1989 |
Long-acting dihydropyridine calcium antagonists. 1. 2-Alkoxymethyl derivatives incorporating basic substituents.
Topics: Amlodipine; Animals; Biological Assay; Biological Availability; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Dogs; Guinea Pigs; Hemodynamics; Kinetics; Male; Nifedipine; Pyridines; Rats; Vasoconstriction | 1986 |
Stereoselectivity of a potent calcium antagonist, 1-benzyl-3-pyrrolidinyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
Topics: Animals; Blood Pressure; Brain; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Coronary Circulation; Coronary Vessels; Dogs; Heart Rate; Male; Molecular Conformation; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship; Vasodilation | 1986 |
Novel calcium antagonists. Synthesis and structure-activity relationship studies of benzothiazoline derivatives.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Guinea Pigs; Heart Conduction System; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Pulmonary Embolism; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Thiazoles | 1988 |
Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; CHO Cells; Cricetinae; Dihydropyridines; Enzyme Inhibitors; Guinea Pigs; Humans; Isradipine; Molecular Structure; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship | 1996 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Digoxin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Gene Expression; Humans; Nifedipine; Paclitaxel; RNA, Messenger; Swine; Tritium; Tumor Cells, Cultured; Verapamil; Vinblastine | 2002 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Effect of [6]-shogaol on cytosolic Ca2+ levels and proliferation in human oral cancer cells (OC2).
Topics: Calcium; Calcium Channels, L-Type; Catechols; Cell Line, Tumor; Cytosol; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Molecular Structure; Mouth Neoplasms; Phospholipase A2 Inhibitors; Protein Kinase C; Pyrrolidinones; Thapsigargin | 2010 |
Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cricetinae; Dihydropyridines; Erythrocytes; Leishmania; Macaca mulatta; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Synthesis of new water-soluble dihydropyridine vasodilators.
Topics: Nicardipine; Nifedipine; Pyridines; Solubility; Structure-Activity Relationship; Vasodilator Agents; Water | 1979 |
Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Dogs; Heart Rate; Hypertension; Hypertension, Renal; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Wistar | 1992 |
Inhibition of sodium pump by bepridil. An in vitro and microcalorimetric study.
Topics: Adenosine Triphosphate; Bepridil; Diltiazem; Erythrocytes; Humans; Kinetics; Nicardipine; Nifedipine; Ouabain; Potassium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1992 |
Effects of nifedipine and nicardipine on glucagon-stimulated gluconeogenesis in primary cultures of rat hepatocytes.
Topics: Animals; Cells, Cultured; Cyclic AMP; Glucagon; Gluconeogenesis; Glucose; Liver; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains | 1992 |
Case report: nifedipine-rifampicin interaction attenuates the effect on blood pressure in a patient with essential hypertension.
Topics: Adrenergic alpha-Antagonists; Aged; Blood Pressure; Drug Interactions; Ethambutol; Female; Humans; Hypertension; Isoniazid; Nicardipine; Nifedipine; Propranolol; Quinazolines; Rifampin | 1992 |
Direct measurement of L-type Ca2+ window current in heart cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium Channels; Dogs; Isoproterenol; Membrane Potentials; Models, Biological; Nicardipine; Nifedipine; Purkinje Fibers | 1992 |
Absence of a direct coupling of a G protein to dihydropyridine binding sites in rat heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channels; Dihydropyridines; GTP-Binding Proteins; Heart; Male; Myocardium; Nicardipine; Nifedipine; Rats; Rats, Wistar | 1992 |
Nilvadipine as a neuroprotective calcium entry blocker in a rat model of global cerebral ischemia. A comparative study with nicardipine hydrochloride.
Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Decerebrate State; Fatty Acids, Nonesterified; Male; Nicardipine; Nifedipine; Rats; Rats, Sprague-Dawley | 1992 |
Comparative cytoprotective effect of dihydropyridine calcium channel blockers against the toxicity of oxidized low density lipoprotein for cultured lymphoid cells.
Topics: Calcium Channel Blockers; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Lipid Peroxidation; Lipoproteins, LDL; Lymphocytes; Nicardipine; Nifedipine; Nimodipine; Nisoldipine | 1992 |
Cardiovascular effects of the new generation calcium antagonist 3-pyridine carboxylic acid 5-[(cyclopropylamino)carbonyl]-1,4-dihydro-2,6-dimethyl-4-(2-nitropheny l) octyl ester.
Topics: Anesthesia; Animals; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Dogs; Female; Heart Conduction System; Hemodynamics; In Vitro Techniques; Male; Nicardipine; Nifedipine; Rabbits; Vasodilator Agents | 1992 |
Sublingual nicardipine versus nifedipine to treat hypertensive urgencies.
Topics: Administration, Sublingual; Adult; Blood Pressure; Emergencies; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine | 1992 |
Antioxidant effects of calcium channel blockers against free radical injury in endothelial cells. Correlation of protection with preservation of glutathione levels.
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Calcium Channel Blockers; Cattle; Cell Survival; Cells, Cultured; Diltiazem; Endothelium, Vascular; Free Radicals; Glutathione; Lipid Peroxidation; Nicardipine; Nifedipine; Sarcolemma; Verapamil | 1992 |
Effects of nilvadipine on neuronal function in the ischemic cat brain.
Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Cats; Cerebrovascular Circulation; Evoked Potentials, Somatosensory; Female; Male; Neurons; Nicardipine; Nifedipine | 1992 |
Rapid desensitization of central beta-adrenoceptors in rat after subacute treatment with imipramine and calcium entry blockers.
Topics: 1-Propanol; Animals; Calcium Channel Blockers; Clonidine; Diltiazem; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drinking Behavior; Fenclonine; Imipramine; Isoproterenol; Ketanserin; Nicardipine; Nifedipine; Oxidopamine; Rats; Receptors, Adrenergic, beta; Verapamil | 1991 |
Inhibitory effects of diltiazem, verapamil, nifedipine, and nicardipine on sympathetic tachycardia in decentralized hearts of anesthetized dogs.
Topics: Analysis of Variance; Animals; Blood Pressure; Coronary Circulation; Diltiazem; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Male; Nicardipine; Nifedipine; Pentobarbital; Sympathetic Nervous System; Tachycardia; Verapamil | 1990 |
Nilvadipine, a new calcium channel blocker, reduces ischemic brain injury in rats.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Nicardipine; Nifedipine; Rats; Rats, Inbred SHR | 1991 |
Effect of TC-81, a new dihydropyridine derivative, on K(+)-induced contraction in rat aorta.
Topics: Animals; Aorta; Calcium; Calcium Radioisotopes; Dihydropyridines; Diltiazem; In Vitro Techniques; Isometric Contraction; Male; Nicardipine; Nifedipine; Papaverine; Potassium; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilator Agents | 1991 |
[Ca++ antagonist and acute brain ischemia: effects of nilvadipine and nicardipine on middle cerebral artery occlusion in rats].
Topics: Acute Disease; Animals; Calcium Channel Blockers; Cerebral Infarction; Constriction; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains | 1991 |
Antagonistic effects of dihydropyridines and verapamil on CaCl2 and 5-HT-evoked contraction in porcine coronary artery.
Topics: Animals; Calcium Chloride; Coronary Vessels; Dihydropyridines; Felodipine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Nimodipine; Serotonin Antagonists; Swine; Verapamil | 1991 |
High-performance liquid chromatographic determination of nifedipine, nicardipine and pindolol using a carbon fibre flow-through amperometric detector.
Topics: Carbon; Chromatography, High Pressure Liquid; Humans; Microelectrodes; Molecular Structure; Nicardipine; Nifedipine; Pindolol | 1991 |
Prolonged inhibition of vascular contraction and calcium influx by the novel 1,4-dihydropyridine calcium antagonist cinaldipine (FRC-8653).
Topics: Animals; Antihypertensive Agents; Calcium; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Time Factors; Vasodilator Agents | 1991 |
Effect of nicardipine on the relationship of renal blood flow and of renal vascular resistance to perfusion pressure in dog kidney.
Topics: Animals; Blood Pressure; Calcium Channel Agonists; Dogs; Dose-Response Relationship, Drug; Female; Male; Nicardipine; Nifedipine; Perfusion; Renal Circulation; Vascular Resistance; Vasoconstriction | 1990 |
Direct measurement of intracellular free calcium in cultured human puerperal myometrial cells stimulated by oxytocin: effects of extracellular calcium and calcium channel blockers.
Topics: Calcium; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Microscopy, Fluorescence; Myometrium; Nicardipine; Nifedipine; Nitrendipine; Oxytocin; Postpartum Period | 1991 |
Clinical significance of ambulatory blood pressure monitoring. Evaluation of severity of hypertension, efficacy of treatment and effects on nighttime blood pressure.
Topics: Blood Pressure Determination; Blood Pressure Monitors; Circadian Rhythm; Delayed-Action Preparations; Heart Rate; Humans; Hypertension; Nicardipine; Nifedipine; Office Visits | 1991 |
Antihypertensive and diuretic effects of YM-09730-5, a new calcium antagonist, in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Diuresis; Diuretics; Heart Rate; Hypertension; Male; Nicardipine; Nifedipine; Organ Size; Rats; Rats, Inbred SHR; Renin; Urodynamics | 1991 |
[Anti-inflammatory effects of verapamil, nifedipine and nicardipine].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Dinoprostone; Female; Inflammation; Male; Mice; Nicardipine; Nifedipine; Rats; Verapamil | 1990 |
Protective effects of calcium channel blockers on hydrogen peroxide induced increases in endothelial permeability.
Topics: Albumins; Calcium Channel Blockers; Capillary Permeability; Cell Membrane Permeability; Cells, Cultured; Diltiazem; Electric Conductivity; Endothelium, Vascular; Humans; Hydrogen Peroxide; Nicardipine; Nifedipine; Verapamil | 1990 |
Tissue selectivity of the novel calcium antagonist sesamodil fumarate in isolated smooth muscles and cardiac muscles.
Topics: Animals; Calcimycin; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nicardipine; Nifedipine; Rabbits; Swine; Thiazoles; Verapamil | 1990 |
Reconsideration of vascular selectivity of dihydropyridine calcium antagonists: comparison of cardiovascular profile of mepirodipine, a novel dihydropyridine consisting of a single stereoisomer with (+)-(S)-(S) conformation, with those of nifedipine and n
Topics: Animals; Atrioventricular Node; Calcium Channel Blockers; Coronary Circulation; Dogs; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Nicardipine; Nifedipine; Papillary Muscles; Sinoatrial Node; Stereoisomerism | 1990 |
[Effects of cardioplegic solution and calcium entry blockers on coronary artery contraction].
Topics: Animals; Calcium Channel Blockers; Cardioplegic Solutions; Coronary Vasospasm; Diltiazem; Dogs; Nicardipine; Nifedipine; Potassium; Potassium Compounds; Verapamil | 1990 |
Effects of calcium channel blockers and hydralazine on plasma glucose levels in streptozotocin-induced diabetic rats in vivo.
Topics: Animals; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Catecholamines; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hexamethonium Compounds; Hydralazine; Male; Nicardipine; Nifedipine; Phentolamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Starvation | 1990 |
Inhibition of histamine release from dispersed human lung and tonsillar mast cells by nicardipine and nifedipine.
Topics: Calcimycin; Calcium Channel Blockers; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Lung; Mast Cells; Methyltransferases; Nicardipine; Nifedipine; Palatine Tonsil; Ultraviolet Rays | 1985 |
Effects of Ca antagonists on the norepinephrine release and contractile responses of isolated canine saphenous veins to high KCl.
Topics: 1-Methyl-3-isobutylxanthine; Anesthetics, Local; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Norepinephrine; Phentolamine; Potassium Chloride; Saphenous Vein; Verapamil | 1985 |
[Inhibitory effect of nicardipine on 45Ca uptake and histamine release in rat mast cells stimulated by antigen].
Topics: Animals; Antigens; Calcium; Calcium Channel Blockers; Depression, Chemical; Histamine Release; Male; Mast Cells; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains | 1985 |
Neuronal differentiation of Ca2+ channel by nerve growth factor.
Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Animals; Calcium; Cell Differentiation; Cell Line; Clone Cells; Ion Channels; Nerve Growth Factors; Neurons; Nicardipine; Nifedipine; Norepinephrine; Pheochromocytoma; Rats | 1985 |
The calcium antagonist, nicardipine, inhibits antigen-stimulated and anti-IgE-induced histamine release from basophilic leucocytes of atopic asthmatics.
Topics: Antibodies, Anti-Idiotypic; Antigens; Asthma; Basophils; Calcium Channel Blockers; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Nicardipine; Nifedipine | 1985 |
[Inhibition of a calcium antagonist, nicardipine, of histamine release from basophil leukocytes of patients with bronchial asthma].
Topics: Adolescent; Adult; Aged; Asthma; Basophils; Calcium Channel Blockers; Child; Depression, Chemical; Female; Histamine Release; Humans; In Vitro Techniques; Male; Middle Aged; Nicardipine; Nifedipine | 1985 |
[Synergism of the calcium reversal phenomenon of potassium depolarizing in the rat uterine muscle by Bay k-8644, a calcium agonist].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Female; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicardipine; Nifedipine; Oxytocin; Potassium; Rats; Uterus | 1985 |
Effects of Bay K 8644 on contraction of the human isolated bronchus and guinea-pig isolated trachea.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Bronchi; Calcium; Calcium Channel Blockers; Guinea Pigs; Histamine; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Potassium Chloride; Trachea; Verapamil | 1986 |
Role of calcium and sodium ions in the inhibitory control of baseline and stimulated prolactin release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium; Dopamine; Female; Nicardipine; Nifedipine; Phorbol Esters; Prolactin; Rats; Rats, Inbred Strains; Sodium; Thyrotropin-Releasing Hormone | 1986 |
Effect of calcium antagonist and agonist on free fatty acid liberation in the ischemic brain of rats.
Topics: Animals; Arachidonic Acids; Brain; Brain Ischemia; Disease Models, Animal; Fatty Acids, Nonesterified; Ion Channels; Male; Nicardipine; Nifedipine; Oleic Acids; Palmitic Acids; Rats; Rats, Inbred Strains; Stearic Acids | 1987 |
Photoaffinity labelling of the cardiac calcium channel. (-)-[3H]azidopine labels a 165 kDa polypeptide, and evidence against a [3H]-1,4-dihydropyridine-isothiocyanate being a calcium-channel-specific affinity ligand.
Topics: Affinity Labels; Animals; Azides; Calcium; Cell Membrane; Dihydropyridines; Electrophoresis, Polyacrylamide Gel; Guinea Pigs; Heart; Hexobendine; Ion Channels; Isothiocyanates; Myocardium; Nicardipine; Nifedipine; Peptides; Pyridines; Rats; Species Specificity; Thiocyanates | 1987 |
Cardiovascular actions of a new dihydropyridine calcium antagonist, 8363-S: comparison with nifedipine and nicardipine in awake, unsedated dogs.
Topics: Administration, Oral; Animals; Calcium Channel Blockers; Cardiovascular System; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Injections, Intravenous; Nicardipine; Nifedipine; Pyridines | 1987 |
Prolonged inhibitory effects of nilvadipine (FR34235) following washout in isolated rabbit aorta and mesenteric artery.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Diltiazem; Female; In Vitro Techniques; Male; Mesenteric Arteries; Nicardipine; Nifedipine; Norepinephrine; Potassium Chloride; Rabbits; Vasodilator Agents | 1988 |
Difference between the effects of atrial natriuretic peptide and calcium antagonist on cytosolic free calcium in cultured vascular smooth muscle cells.
Topics: Animals; Atrial Natriuretic Factor; Calcium; Calcium Channel Blockers; Cells, Cultured; Cytosol; Male; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence | 1989 |
Interaction between isoproterenol and dihydropyridines in heart cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cells, Cultured; Chick Embryo; Dihydropyridines; Heart; Isoproterenol; Myocardial Contraction; Myocardium; Nicardipine; Nifedipine; Time Factors | 1989 |
Nicardipine inhibits axon conduction but causes dual changes of acetylcholine release in the mouse motor nerve.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Action Potentials; Animals; Axonal Transport; Axons; Chick Embryo; Diaphragm; Diltiazem; Female; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Motor Neurons; Muscle Contraction; Nicardipine; Nifedipine; Sodium Channels; Succinylcholine; Verapamil | 1989 |
Effects of calcium antagonists and nitroglycerin on atrial natriuretic peptide in normal subjects and patients with essential hypertension.
Topics: Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Nitroglycerin; Renin-Angiotensin System | 1989 |
Intrasynaptosomal free calcium concentration is increased by phorbol esters via a 1,4-dihydropyridine-sensitive (L-type) Ca2+ channel.
Topics: Animals; Calcium; Calcium Channels; Dihydropyridines; Fluorescent Dyes; In Vitro Techniques; Male; Nicardipine; Nifedipine; Phorbol Esters; Rats; Rats, Inbred Strains; Synaptosomes; Tetradecanoylphorbol Acetate | 1989 |
Characterization of membrane calcium channels in nonpregnant and pregnant human uterus.
Topics: Adult; Binding Sites; Calcium Channels; Cell Membrane; Female; Humans; Middle Aged; Myometrium; Nicardipine; Nifedipine; Nitrendipine; Pregnancy; Verapamil | 1989 |
[New approach to the development of Ca antagonists].
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; Humans; Hypertension; Nicardipine; Nifedipine; Verapamil | 1989 |
[Calcium antagonists in the treatment of hypertension].
Topics: Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Nicardipine; Nifedipine; Verapamil | 1989 |
Effects of S-312, a new calcium antagonist, on the mechanical and electrophysiological responses of isolated cardiovascular preparations.
Topics: Animals; Arteries; Calcium Channel Blockers; Cecum; Dihydropyridines; Electrophysiology; Guinea Pigs; Heart; Heart Conduction System; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardial Contraction; Nicardipine; Nifedipine; Rabbits; Sinoatrial Node; Vasodilation | 1989 |
Natriuretic action of manidipine hydrochloride, a new calcium channel blocker, in spontaneously hypertensive rats.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Electrolytes; Male; Natriuresis; Nicardipine; Nifedipine; Nitrobenzenes; Piperazines; Rats; Rats, Inbred SHR; Renal Circulation; Urodynamics | 1989 |
Suppression of atherogenesis in cholesterol-fed rabbits treated with nilvadipine, a new vasoselective calcium entry blocker.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Blood Pressure; Calcium; Calcium Channel Blockers; Cholesterol; Liver; Male; Myocardium; Nicardipine; Nifedipine; Rabbits | 1989 |
[Comparative study of nifedipine and nicardipine in the treatment of hypertensive crisis after aortocoronary bypass].
Topics: Coronary Artery Bypass; Humans; Hypertension; Nicardipine; Nifedipine; Postoperative Complications | 1989 |
In vivo characterization of combination antitumor chemotherapy with calcium channel blockers and cis-diamminedichloroplatinum(II).
Topics: Animals; Calcium Channel Blockers; Cisplatin; Diltiazem; Drug Evaluation, Preclinical; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Imidazoles; Lung Neoplasms; Melanoma, Experimental; Mice; Nicardipine; Nifedipine; Trifluoperazine; Verapamil | 1989 |
Effects of calcium channel blockers and hydralazine on epinephrine-induced hyperglycemia in vivo.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Epinephrine; Food Deprivation; Glucose Tolerance Test; Hydralazine; Hyperglycemia; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Aspirin with an adrenergic or a calcium-channel-blocking agent as new combination therapy for arterial thrombosis.
Topics: Aspirin; Drug Synergism; Ethanolamines; Humans; Labetalol; Nicardipine; Nifedipine; Platelet Aggregation; Thrombosis | 1985 |
Effects of nicardipine on coronary blood flow, left ventricular inotropic state and myocardial metabolism in patients with angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Coronary Circulation; Glutamine; Humans; Lactates; Lactic Acid; Male; Middle Aged; Myocardial Contraction; Myocardium; Nicardipine; Nifedipine; Norepinephrine; Oxygen Consumption | 1985 |
Effects of nicardipine on cardiac volume at rest and during exercise-induced angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Cardiac Volume; Dose-Response Relationship, Drug; Humans; Middle Aged; Nicardipine; Nifedipine; Physical Exertion | 1985 |
Effect of nicardipine on left ventricular function and on angina induced by atrial pacing in patients with coronary artery disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Dose-Response Relationship, Drug; Electrocardiography; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Nicardipine; Nifedipine; Vascular Resistance | 1985 |
Nicardipine increases cyclosporin blood levels.
Topics: Cyclosporins; Drug Interactions; Humans; Nicardipine; Nifedipine | 1986 |
Suppression of clofibrate-induced peroxisome proliferation in rat liver by nicardipine, a calcium antagonist.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acyl-CoA Dehydrogenase; Animals; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Catalase; Clofibrate; D-Amino-Acid Oxidase; Diltiazem; Enoyl-CoA Hydratase; Enzyme Induction; Enzyme Inhibitors; Fatty Acid Desaturases; Liver; Male; Microbodies; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Triglycerides | 1988 |
Nilvadipine attenuates ischemic degradation of gerbil brain cytoskeletal proteins.
Topics: Animals; Brain; Brain Ischemia; Calmodulin-Binding Proteins; Clathrin; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Gerbillinae; Male; Microtubule-Associated Proteins; Nicardipine; Nifedipine; Nimodipine | 1989 |
Hypotensive effects of dihydropyridine derivatives.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Hydralazine; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1985 |
The effect of calcium-blockers nicardipine, darodipine, PN-200-110 and nifedipine on insulin release from isolated rat pancreatic islets.
Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isradipine; Male; Nicardipine; Nifedipine; Oxadiazoles; Rats; Rats, Inbred Strains | 1986 |
[Comparative effects of dihydropyridine inhibitors of calcium penetration on spontaneous contraction of the isolated heart atria in the guinea pig].
Topics: Aminophylline; Animals; Atrial Function; Calcium; Calcium Chloride; Depression, Chemical; Drug Interactions; Female; Guinea Pigs; Isoproterenol; Male; Myocardial Contraction; Nicardipine; Nifedipine; Nitrendipine | 1988 |
Effects of dihydropyridine calcium channel blocking drugs on rat brain muscarinic and alpha-adrenergic receptors.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Dioxanes; Gallopamil; In Vitro Techniques; Nicardipine; Nifedipine; Pyridines; Quinuclidinyl Benzilate; Rats; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Receptors, Nicotinic; Stereoisomerism | 1985 |
[Enhanced cytotoxic effect of Adriamycin and vincristine against PC-6 (human lung cancer cell line) and Hattori (human breast cancer cell line)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Small Cell; Cell Line; Doxorubicin; Drug Synergism; Female; Humans; Lung Neoplasms; Nicardipine; Nifedipine; Oxyfedrine; Trichlormethiazide; Vincristine | 1985 |
A possible action of nicardipine on the cardiac sarcolemmal Na+-Ca2+ exchange.
Topics: Adenosine Triphosphatases; Animals; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Channel Blockers; Heart; In Vitro Techniques; Male; Myocardium; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase | 1985 |
Effect of ryodipine on electromechanical parameters of heart and vessels, cAMP phosphodiesterase activity and swelling-contraction cycle of mitochondria.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anura; Calcium Channel Blockers; Cardiovascular Agents; Cattle; Dihydropyridines; Electric Stimulation; Electrophysiology; Heart; In Vitro Techniques; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nicardipine; Nifedipine; Pyridines; Rabbits; Rats | 1985 |
Effects of nicardipine on aldosterone release and pressor mechanisms.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Heart Rate; Humans; Hydrocortisone; Male; Nicardipine; Nifedipine; Norepinephrine; Renin | 1985 |
Augmentation of succinylcholine-induced neuromuscular blockade by calcium channel antagonists.
Topics: Animals; Bepridil; Calcium Channel Blockers; Drug Synergism; In Vitro Techniques; Neuromuscular Junction; Nicardipine; Nifedipine; Pyrrolidines; Rana pipiens; Receptors, Nicotinic; Succinylcholine; Synaptic Transmission; Verapamil | 1986 |
Antihypertensive effects of the new calcium antagonist benidipine hydrochloride in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Heart Rate; Hydralazine; Hypertension; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin; Urination | 1988 |
Inhibition of whole blood platelet aggregation by nicardipine, and synergism with prostacyclin in-vitro.
Topics: Adenosine Diphosphate; Antihypertensive Agents; Arachidonic Acid; Arachidonic Acids; Collagen; Drug Synergism; Epoprostenol; Female; Humans; Kinetics; Male; Nicardipine; Nifedipine; Platelet Aggregation; Reference Values; Thromboxane A2; Thromboxane B2 | 1986 |
Effects of calcium antagonists on low density lipoprotein metabolism in human arterial smooth muscle cells.
Topics: Arteriosclerosis; Calcium Channel Blockers; Cells, Cultured; Humans; Lipoproteins, LDL; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Verapamil | 1988 |
Slow dissociation of the new slow-onset and long-acting calcium antagonist benidipine hydrochloride from 3H-nitrendipine binding sites.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Male; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred Strains | 1988 |
Antihypertensive effects of intravenous administration of benidipine hydrochloride and some other calcium antagonists in conscious, spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intravenous; Male; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Verapamil | 1988 |
Antihypertensive effects of the new calcium antagonist benidipine hydrochloride in conscious, renal-hypertensive dogs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dogs; Female; Heart Rate; Hypertension, Renal; Male; Nicardipine; Nifedipine; Nitrendipine; Propranolol | 1988 |
Vasodilating effects of the new calcium antagonist benidipine hydrochloride in anesthetized dogs and cats.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Cats; Cerebral Cortex; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intra-Arterial; Injections, Intravenous; Male; Nicardipine; Nifedipine; Papaverine; Vasodilation; Vasodilator Agents | 1988 |
[Controlled hypotension: a future indication for calcium inhibitors?].
Topics: Anesthesia, General; Blood Pressure; Calcium Channel Blockers; Diltiazem; Humans; Hypotension, Controlled; Nicardipine; Nifedipine; Postoperative Period; Verapamil | 1988 |
Effects of Ca++-antagonists on systemic capacitance vessels and venous return curves of dogs--a study with mean circulatory pressure.
Topics: Animals; Blood Pressure; Blood Vessels; Blood Volume; Calcium Channel Blockers; Cardiac Output; Diltiazem; Dogs; Hematocrit; Infusions, Intravenous; Nicardipine; Nifedipine; Norepinephrine; Reproducibility of Results; Vascular Resistance; Verapamil | 1988 |
Effects of the Ca-antagonist nicardipine on K+ currents and Na+-Ca2+ exchange in frog atrial fibres.
Topics: Animals; Anura; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Heart; In Vitro Techniques; Ion Exchange; Muscle Tonus; Myocardial Contraction; Nicardipine; Nifedipine; Potassium Channels; Sodium | 1988 |
The effects of the novel anti-anginal compound RS 43285 on myocardial conduction in the anaesthetized dog.
Topics: Acetanilides; Anesthesia; Angina Pectoris; Animals; Atrioventricular Node; Dogs; Electrocardiography; Heart Conduction System; Male; Nicardipine; Nifedipine; Piperazines; Ranolazine; Verapamil | 1988 |
High performance liquid chromatography of a new 1,4-dihydropyridine: applications to pharmacokinetic study in dogs.
Topics: Administration, Oral; Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dogs; Indicators and Reagents; Injections, Intravenous; Light; Male; Nicardipine; Nifedipine; Nitrendipine | 1988 |
Comparison of the effects of calcium channel blockers and antiarrhythmic drugs on digitalis-induced oscillatory afterpotentials on canine Purkinje fiber.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Digitalis; Diltiazem; Dogs; Electric Stimulation; Female; Heart Conduction System; Male; Mexiletine; Nicardipine; Nifedipine; Nitrendipine; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Purkinje Fibers; Verapamil | 1987 |
Compared effects of calcium entry blockers on calcium-induced tension in rat isolated cerebral and peripheral resistance vessels.
Topics: Animals; Calcium; Calcium Channel Blockers; Cerebral Arteries; Diltiazem; Female; In Vitro Techniques; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Serotonin; Vascular Resistance; Verapamil | 1987 |
Electrophysiological analysis of the action of nifedipine and nicardipine on myocardial fibers.
Topics: Action Potentials; Animals; Anura; Calcium Channel Blockers; Heart; In Vitro Techniques; Nicardipine; Nifedipine; Photolysis | 1987 |
[Mechanism and overcoming of resistance in ACNU-resistant sublines of rat brain tumors].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Membrane Permeability; Drug Resistance; Glioma; Nicardipine; Nifedipine; Nimustine; Nitrosourea Compounds; Rats; Verapamil | 1986 |
Effects of nicardipine on frog skeletal muscle in normal and calcium-free media.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Muscle Contraction; Muscles; Nicardipine; Nifedipine; Rana catesbeiana; Ranidae; Saline Solution, Hypertonic; Tetrodotoxin | 1986 |
Effects of calcium entry blockers on blood pressure and heart rate in neurogenic hypertensive dogs.
Topics: Animals; Bepridil; Blood Pressure; Calcium Channel Blockers; Denervation; Diltiazem; Dogs; Female; Heart Rate; Hypertension; Male; Nicardipine; Nifedipine; Pyrrolidines; Sinoatrial Node; Verapamil | 1987 |
[Influence of a calcium channel blocker, nicardipine, on glucoregulatory hormones and glucose metabolism].
Topics: Adult; Blood Glucose; Calcium Channel Blockers; Catecholamines; Female; Growth Hormone; Humans; Hysterectomy; Insulin; Neuroleptanalgesia; Nicardipine; Nifedipine | 1986 |
Comparative antihypertensive effects of nifedipine and nicardipine in adult and aged spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hypertension; Nicardipine; Nifedipine; Rats; Rats, Inbred SHR | 1987 |
Effects of nicardipine and nifedipine in chronic heart failure: a non invasive study.
Topics: Aged; Chronic Disease; Exercise Test; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Radiography; Random Allocation; Stroke Volume; Systole | 1987 |
Changes in myocardial metabolism during therapy in patients with chronic stable angina: a comparison of long-term dosing with propranolol and nicardipine.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Cardiac Pacing, Artificial; Chronic Disease; Exercise Test; Female; Heart Rate; Humans; Lactates; Male; Middle Aged; Myocardium; Nicardipine; Nifedipine; Propranolol; Tachycardia; Time Factors | 1986 |
Use of nicardipine in the anesthetic management of pheochromocytoma.
Topics: Adult; Anesthesia, Local; Blood Pressure; Cardiac Output; Epinephrine; Female; Fentanyl; Heart Rate; Humans; Hypertension; Infusions, Parenteral; Intraoperative Period; Nicardipine; Nifedipine; Norepinephrine; Pheochromocytoma; Preanesthetic Medication; Vascular Resistance | 1986 |
Pharmacokinetic, haemodynamic and radionuclide studies with nicardipine in coronary artery disease.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Cardiac Output; Coronary Disease; Heart Rate; Hemodynamics; Humans; Kinetics; Male; Middle Aged; Nicardipine; Nifedipine; Radionuclide Imaging; Time Factors | 1986 |
[Effect of the calcium entry blockers nicardipine and nimodipine on cerebral function following global anoxia in the rat].
Topics: Animals; Brain; Calcium Channel Blockers; Hypoxia, Brain; Male; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Rats; Rats, Inbred Strains; Resuscitation | 1986 |
[Does nicardipine improve chronic cerebrovascular insufficiency?].
Topics: Cerebrovascular Disorders; Humans; Nicardipine; Nifedipine; Vasodilator Agents | 1986 |
The metabolism of nicardipine hydrochloride in healthy male volunteers.
Topics: Adult; Animals; Biotransformation; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Humans; Male; Nicardipine; Nifedipine | 1986 |
Acute and chronic effects of nicardipine on systolic and diastolic left ventricular performance in patients with heart failure: a pilot study.
Topics: Administration, Oral; Adult; Aged; Calcium Channel Blockers; Cardiac Output; Dose-Response Relationship, Drug; Drug Administration Schedule; Heart Failure; Humans; Infusions, Parenteral; Male; Middle Aged; Myocardial Contraction; Nicardipine; Nifedipine; Radionuclide Imaging; Stroke Volume; Technetium; Technetium Tc 99m Pyrophosphate; Tin Polyphosphates | 1986 |
Nicardipine: protection against brain hypoxia.
Topics: Animals; Cerebral Cortex; Electroencephalography; Hypoxia, Brain; Male; Mice; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Time Factors; Vasodilator Agents | 1986 |
Effect of calcium antagonists on adrenergic mechanisms in canine saphenous veins.
Topics: Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Norepinephrine; Saphenous Vein; Sympathetic Nervous System; Tyramine | 1986 |
Autopsy findings of the coronary arteries of variant angina with Raynaud's phenomenon of the tongue.
Topics: Adult; Alprostadil; Angina Pectoris, Variant; Cardiac Catheterization; Coronary Vessels; Drug Therapy, Combination; Electrocardiography; Humans; Isosorbide Dinitrate; Male; Nicardipine; Nifedipine; Raynaud Disease; Tongue Diseases; Valsalva Maneuver | 1986 |
Comparative effects of nicardipine, a new calcium antagonist, on size of myocardial infarction after coronary artery occlusion in dogs.
Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodynamics; Male; Myocardial Infarction; Nicardipine; Nifedipine; Time Factors | 1986 |
[Protective effect of nicardipine in an experimental model of transient myocardial ischemia in anesthetized dogs].
Topics: Animals; Coronary Disease; Dogs; Electrocardiography; Female; Hemodynamics; Lactates; Lactic Acid; Male; Nicardipine; Nifedipine | 1986 |
The acute haemodynamic effects of nicardipine in patients with chronic left ventricular failure.
Topics: Adult; Aged; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine | 1986 |
[Hemodynamics during induced hypotension with continuous administration of nicardipine].
Topics: Adult; Female; Hemodynamics; Humans; Hypotension, Controlled; Injections, Intravenous; Male; Middle Aged; Neuroleptanalgesia; Nicardipine; Nifedipine | 1986 |
[Influence of calcium channel blocker on adrenal function during the peri-operative period].
Topics: Adolescent; Adrenal Glands; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Catecholamines; Humans; Intraoperative Period; Middle Aged; Neuroleptanalgesia; Nicardipine; Nifedipine | 1986 |
[Isotope effects in the biological processes--isotope effect in the drug metabolism study].
Topics: Acetophenones; Aminopyrine; Animals; Antihypertensive Agents; Deuterium; Ephedrine; Humans; Isotope Labeling; Kinetics; Nicardipine; Nifedipine; Tritium | 1986 |
Effect of nicardipine on rest and exercise hemodynamics in chronic congestive heart failure.
Topics: Adult; Aged; Blood Pressure; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Norepinephrine; Physical Exertion; Pulmonary Gas Exchange; Stroke Volume; Vascular Resistance; Vasodilation | 1986 |
Effect of calcium antagonists on reactive hypoglycemia associated with hyperinsulinemia.
Topics: Adult; Aged; C-Peptide; Calcium Channel Blockers; Diltiazem; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Male; Middle Aged; Nicardipine; Nifedipine | 1986 |
Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hydralazine; Hypertension, Renal; Kinetics; Male; Nicardipine; Nifedipine; Nimodipine; Nisoldipine; Time Factors | 1986 |
Nicardipine releases sustained coronary arterial constriction induced by acetylcholine in the rhesus monkey.
Topics: Acetylcholine; Animals; Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Disease Models, Animal; Female; Hemodynamics; Macaca mulatta; Male; Nicardipine; Nifedipine; Vasoconstriction; Vasodilator Agents | 1985 |
Vasodilatory effect of nicardipine and verapamil in the forearm of hypertensive as compared with normotensive man.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Forearm; Humans; Hypertension; Middle Aged; Nicardipine; Nifedipine; Renin; Vascular Resistance; Vasodilator Agents; Verapamil | 1985 |
Influence of nicardipine on blood pressure, renal function and plasma aldosterone in normotensive volunteers.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Humans; Kidney; Male; Nicardipine; Nifedipine; Renin; Sodium | 1985 |
Calcium channel blockers--are they diuretics?
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diuretics; Female; Humans; Hypertension; Kidney Tubules; Male; Middle Aged; Nicardipine; Nifedipine; Renin | 1985 |
Cardiovascular, baroreflex and humoral responses in hypertensive patients during nicardipine therapy.
Topics: Adult; Aldosterone; Carotid Arteries; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Physical Exertion; Pressoreceptors; Renin; Vasodilator Agents | 1985 |
Calcium-dependent interactions of an ionophore A23187 with calmodulin.
Topics: Animals; Calcimycin; Calcium; Calcium-Binding Proteins; Calmodulin; Cells, Cultured; Membranes; Muscle, Smooth; Nicardipine; Nifedipine; Protein Binding; Proteins; Rabbits; Solubility; Spectrometry, Fluorescence | 1985 |
Mitogen and co-mitogen stimulation of lymphocytes inhibited by three Ca++ antagonists.
Topics: Animals; Calcimycin; Calcium Channel Blockers; Cattle; Cell Division; Concanavalin A; Drug Synergism; Gallic Acid; Lectins; Lymphocyte Activation; Lymphocytes; Mitogens; Nicardipine; Nifedipine; Tetradecanoylphorbol Acetate; Time Factors; Verapamil; Wheat Germ Agglutinins | 1985 |
[Acute and chronic effects of a new calcium blocker, nicardipine, on renal hemodynamics in arterial hypertension].
Topics: Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Renal Circulation | 1985 |
[Calcium antagonists and glycoregulation: dissociated effects of nicardipine on vascular tonus and insulin secretion].
Topics: Adult; Aged; Animals; Calcium Channel Blockers; Female; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Vascular Resistance | 1985 |
A study of the long-term efficacy and tolerability of oral nicardipine in hypertensive patients.
Topics: Administration, Oral; Adult; Aged; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine | 1985 |
Isolated rat cardiac myocytes as an experimental model to study calcium overload: the effect of calcium-entry blockers.
Topics: Animals; Calcium; Calcium Channel Blockers; Cinnarizine; Diltiazem; Flunarizine; Heart; Lidoflazine; Male; Myocardial Contraction; Myocardium; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Time Factors; Verapamil; Veratrine | 1986 |
Effects of nicardipine on left ventricular function and energetics in man.
Topics: Angina Pectoris; Calcium Channel Blockers; Cardiac Output; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Infusions, Parenteral; Male; Middle Aged; Myocardial Contraction; Myocardium; Nicardipine; Nifedipine; Oxygen | 1986 |
Intranasal delivery of nicardipine in the rat.
Topics: Administration, Intranasal; Animals; Biological Availability; Injections, Intravenous; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains | 1986 |
Effect of nicardipine HCl on prematurely induced uterine activity in the pregnant rabbit.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electromyography; Female; Nicardipine; Nifedipine; Pregnancy; Pulse; Rabbits; Time Factors; Uterine Contraction; Uterus | 1985 |
Coronary and systemic hemodynamic effects of nicardipine.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Cardiac Catheterization; Coronary Circulation; Coronary Vessels; Heart; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Nicardipine; Nifedipine; Stroke Volume; Vascular Resistance | 1985 |
Myocardial ischemia during intravenous nicardipine administration.
Topics: Aged; Coronary Disease; Hemodynamics; Humans; Male; Nicardipine; Nifedipine; Oxygen Consumption; Vasodilator Agents | 1985 |
[Effects of combination therapy of carmofur and nicardipine of human gastric cancer in nude mice].
Topics: Animals; Cell Line; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nicardipine; Nifedipine; Stomach Neoplasms | 1985 |
Intracellular Ca++ antagonist, HA1004: pharmacological properties different from those of nicardipine.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Coronary Circulation; Dogs; Heart Ventricles; Hemodynamics; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Renal Artery; Renal Circulation; Sulfonamides; Ventricular Function | 1985 |
[Calcium antagonist enhances the effect of adriamycin].
Topics: Animals; Calcium Channel Blockers; Carcinoma, Ehrlich Tumor; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Female; Mice; Nicardipine; Nifedipine | 1985 |
Regional vasodilating and cardiac effects of nicardipine in anaesthetized open chest dog.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Femoral Artery; Heart; Heart Rate; Nicardipine; Nifedipine; Papaverine; Regional Blood Flow; Vascular Resistance; Vasodilator Agents; Verapamil | 1985 |
Calcium antagonistic properties of nicardipine, a dihydropyridine derivative assessed in isolated cerebral arteries and cardiac muscle.
Topics: Animals; Basilar Artery; Calcium Channel Blockers; Cardiac Glycosides; Cerebral Arteries; Cymarine; Dogs; Electric Stimulation; Female; Heart; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nicardipine; Nifedipine; Rabbits; Serotonin; Species Specificity | 1985 |
Effects of calcium antagonists on smooth muscle membranes of the canine stomach.
Topics: Action Potentials; Animals; Atropine; Calcium Channel Blockers; Cell Membrane; Choline; Diltiazem; Dogs; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Male; Muscle, Smooth; Nicardipine; Nifedipine; Stomach | 1985 |
Acute and subacute toxicity of 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1 ,4-dihydropyridine (PP-1466).
Topics: Administration, Oral; Animals; Blood Chemical Analysis; Body Weight; Calcium Channel Blockers; Dogs; Female; Lethal Dose 50; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred ICR; Nicardipine; Nifedipine; Organ Size; Protoporphyrins; Rabbits; Rats; Rats, Inbred Strains; Sex Factors; Species Specificity; Time Factors | 1985 |
Proceedings of the First International Symposium on Nicardipine. Brussels, Belgium, September 1984.
Topics: Animals; Calcium Channel Blockers; Humans; Nicardipine; Nifedipine | 1985 |
The effect of acute and chronic nicardipine therapy on forearm arterial haemodynamics in essential hypertension.
Topics: Blood Pressure; Calcium; Calcium Channel Blockers; Female; Forearm; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Vascular Resistance | 1985 |
The effect of nicardipine on blood pressure, its variability and reflex cardiac control.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Physical Exertion; Posture; Pressoreceptors; Reflex; Valsalva Maneuver | 1985 |
Immediate and long-term effects of nicardipine, at rest and during exercise, in patients with coronary artery disease.
Topics: Aged; Calcium Channel Blockers; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Physical Exertion | 1985 |
The acute haemodynamic effects of oral nicardipine.
Topics: Administration, Oral; Adult; Calcium Channel Blockers; Female; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine | 1985 |
The metabolism and pharmacokinetics of nicardipine hydrochloride in man.
Topics: Administration, Oral; Biological Availability; Calcium Channel Blockers; Food; Humans; Infusions, Parenteral; Kinetics; Male; Nicardipine; Nifedipine | 1985 |
Nicardipine in models of myocardial infarction.
Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Heart Rate; Hemodynamics; Male; Myocardial Infarction; Nicardipine; Nifedipine; Papio; Verapamil | 1985 |
Intracranial effects of nicardipine.
Topics: Blood Pressure; Brain; Calcium Channel Blockers; Humans; Intracranial Pressure; Nicardipine; Nifedipine; Oxygen | 1985 |
Cardiovascular pharmacology of nicardipine in animals.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular System; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; In Vitro Techniques; Macaca mulatta; Male; Methacholine Compounds; Nicardipine; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasodilator Agents | 1985 |
[Effect of nicardipine on airway dynamics during general anesthesia].
Topics: Adult; Airway Resistance; Anesthesia, General; Calcium Channel Blockers; Female; Humans; Lung Compliance; Male; Middle Aged; Nicardipine; Nifedipine | 1985 |
Effects of Ca2+ antagonist, nicardipine, on experimental asthma with special reference to slow reacting substance of anaphylaxis.
Topics: Airway Resistance; Animals; Antigens; Asthma; Calcium Channel Blockers; Guinea Pigs; Male; Nicardipine; Nifedipine; Ovalbumin; SRS-A | 1985 |
Blood glucose control by an artificial endocrine pancreas in a patient with phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Blood Glucose; Calcium Channel Blockers; Catecholamines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Insulin Infusion Systems; Kinetics; Male; Middle Aged; Nicardipine; Nifedipine; Pheochromocytoma | 1985 |
[Treatment of arterial hypertension with a calcium-channel blocking agent, nicardipine hydrochloride].
Topics: Adult; Aged; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine | 1985 |
[Effect of nicardipine on cholesterol-fed S.H.R].
Topics: Animals; Aorta; Arteriosclerosis; Body Weight; Heart Rate; Hyperlipidemias; Hypertension; Lipids; Liver; Male; Myocardium; Nicardipine; Nifedipine; Organ Size; Rats; Rats, Inbred SHR | 1985 |
Potentiation of vincristine effect in human and murine gliomas by calcium channel blockers or calmodulin inhibitors.
Topics: Animals; Brain Neoplasms; Calcium Channel Blockers; Calmodulin; Drug Synergism; Glioma; Humans; In Vitro Techniques; Mice; Mice, Inbred C57BL; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Verapamil; Vincristine | 1985 |
[Relation of Ca2+ efflux from the heart to the concentration of Ca-channel blockers].
Topics: Animals; Calcium; Calcium Channel Blockers; Heart; In Vitro Techniques; Myocardium; Nicardipine; Nifedipine; Rana ridibunda; Verapamil | 1985 |
[Chronic cerebral vascular pathology].
Topics: Age Factors; Brain Diseases; Cerebrovascular Disorders; Diagnosis, Differential; Humans; Nicardipine; Nifedipine | 1985 |
Nicardipine and nifedipine: effects on diuresis and serum aldosterone levels in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Diuresis; Hypertension; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred SHR; Renal Circulation | 1985 |
Pharmacological investigation of the mechanisms of platelet-activating factor induced mortality in the mouse.
Topics: Anaphylaxis; Animals; Chloroquine; Chlortetracycline; Dexamethasone; Dose-Response Relationship, Drug; Female; Indomethacin; Injections, Intravenous; Male; Mice; Mice, Inbred DBA; Naproxen; Nicardipine; Nifedipine; Platelet Activating Factor; Pyrazoles; Quinacrine; Tetracycline; Verapamil | 1985 |
Effects of nicardipine on ischemic mechanical failure and tissue injury in isolated perfused rat heart.
Topics: Adenine Nucleotides; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Creatine Kinase; Heart Rate; Lactates; Lactic Acid; Male; Nicardipine; Nifedipine; Rats | 1985 |
[Effect of calcium antagonists on the portal vein].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Carbon Tetrachloride Poisoning; Cats; Diltiazem; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Portal Vein; Regional Blood Flow | 1985 |
Increase in the slow inward current by intracellularly applied nifedipine and nicardipine in single ventricular cells of the guinea-pig heart.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channel Blockers; Electrocardiography; Guinea Pigs; Heart Ventricles; Intracellular Fluid; Ion Channels; Nicardipine; Nifedipine | 1984 |
Human red blood cells--an ideal model system for the action of calcium agonists and antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Erythrocytes; Humans; Ion Channels; Nicardipine; Nifedipine; Nitrendipine; Pyridines; Stimulation, Chemical; Verapamil | 1984 |
Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.
Topics: Animals; Binding Sites; Cattle; Dihydropyridines; Electrophysiology; Heart Conduction System; Ion Channels; Membrane Potentials; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Purkinje Fibers; Pyridines; Verapamil | 1984 |
Pressor response to beta-blocking drugs.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Female; Humans; Hypertension; Isoproterenol; Middle Aged; Nicardipine; Nifedipine; Norepinephrine; Pressoreceptors | 1984 |
Electrical components contributing to the nerve-mediated contractions in the smooth muscles of the rabbit ear artery.
Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guanethidine; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Phentolamine; Physical Stimulation; Prazosin; Rabbits; Sympathetic Nervous System; Tetrodotoxin; Yohimbine | 1983 |
Specific and non-specific desensitization of guinea-pig ileal smooth muscle.
Topics: Animals; Calcium; Calcium Channel Blockers; Dioxolanes; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Parasympatholytics; Potassium; Receptors, Muscarinic; Substance P | 1984 |
[Effects of nicardipine on vertebral vascular resistance in anesthetized dogs and spontaneous activity in mice].
Topics: Anesthesia; Animals; Dogs; Female; Male; Mice; Motor Activity; Nicardipine; Nifedipine; Pyridines; Vascular Resistance; Vasodilator Agents | 1983 |
Dissociation of cyclic AMP and contractile responses to isoprenaline: effects of a dihydropyridine derivative, nicardipine (YC-93), on canine ventricular muscle.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Calcium; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Female; Gallopamil; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nicardipine; Nifedipine; Papaverine; Pyridines; Theophylline; Vasodilator Agents | 1980 |
A possible mechanism for relaxation of rat uterine smooth muscle by nicardipine hydrochloride (YC-93), a new potent vasodilator.
Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Female; In Vitro Techniques; Microsomes; Muscle Contraction; Muscle Relaxation; Myometrium; Nicardipine; Nifedipine; Phosphoric Diester Hydrolases; Protein Kinases; Pyridines; Rats; Rats, Inbred Strains; Uterus; Vasodilator Agents | 1981 |
Interaction of calcium antagonists with cyclic AMP phosphodiesterases and calmodulin.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium-Binding Proteins; Calmodulin; Chickens; Cytosol; Dogs; Humans; Kidney; Kinetics; Lymphocytes; Myocardium; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Pyridines; Rats; Spectrometry, Fluorescence | 1982 |
Nicardipine actions on smooth muscle cells and neuromuscular transmission in the guinea-pig basilar artery.
Topics: Adenosine Triphosphate; Animals; Basilar Artery; Calcium; Electric Stimulation; Female; Guinea Pigs; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Nicardipine; Nifedipine; Potassium; Pyridines; Synaptic Transmission | 1983 |
Excitatory effect of the most potent marine toxin, maitotoxin, on the guinea-pig vas deferens.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Membrane; Chlorpheniramine; Dose-Response Relationship, Drug; Guinea Pigs; Ion Channels; Male; Marine Toxins; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Norepinephrine; Oxocins; Phentolamine; Reserpine; Tetrodotoxin; Vas Deferens; Verapamil | 1983 |
The efflux of spin label entrapped in human erythrocyte ghosts when suspended in hyposmolar solutions. The effect of chlorpromazine, trifluoperazine, nicardipine and some other membrane active substances.
Topics: Calcium Channel Blockers; Chlorpromazine; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; Nicardipine; Nifedipine; Osmolar Concentration; Trifluoperazine; Vasodilator Agents | 1984 |
Tissue response selectivity of calcium antagonists is not due to heterogeneity of [3H]-nitrendipine binding sites.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Diltiazem; Female; Gallopamil; In Vitro Techniques; Isometric Contraction; Kinetics; Membranes; Muscle, Smooth, Vascular; Myocardium; Nicardipine; Nifedipine; Organ Specificity; Rabbits; Receptors, Nicotinic; Verapamil | 1984 |
Differential effect of a dihydropyridine derivative to Ca2+ entry pathways in neuronal preparations.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Cerebral Cortex; Clone Cells; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Nicardipine; Nifedipine; Pheochromocytoma; Potassium; Rats; Synaptic Transmission; Synaptosomes | 1984 |
Antihypertensive drugs: their postural hypotensive effect and their blood pressure lowering activity in conscious normotensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hydrochlorothiazide; Hypotension, Orthostatic; Male; Minoxidil; Nicardipine; Nifedipine; Nitroprusside; Pentolinium Tartrate; Phentolamine; Prazosin; Rats; Rats, Inbred Strains | 1983 |
Inhibition by calcium antagonist of coupling of insulin binding and insulin action on glucose transport in isolated fat cells.
Topics: Adipose Tissue; Animals; Biological Transport; Calcium Channel Blockers; Cells, Cultured; Glucose; In Vitro Techniques; Insulin; Nicardipine; Nifedipine; Rats; Time Factors | 1984 |
Use of calcium antagonists as monotherapy in the management of hypertension.
Topics: Calcium; Calcium Channel Blockers; Humans; Hypertension; Nicardipine; Nifedipine; Nitroprusside; Prazosin; Renin; Vasodilation; Verapamil | 1984 |
Sodium cromoglycate, verapamil and nicardipine antagonism to leukotriene D4 bronchoconstriction.
Topics: Airway Resistance; Animals; Bronchi; Cromolyn Sodium; Guinea Pigs; Lung Compliance; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Pyridines; SRS-A; Trachea; Verapamil | 1983 |
Calcium dependency of aortic smooth muscle cell migration induced by 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid. Effects of A23187, nicardipine and trifluoperazine.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Anti-Bacterial Agents; Aorta, Thoracic; Arachidonic Acids; Calcimycin; Calcium; Calcium Channel Blockers; Cell Movement; Male; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Pyridines; Rats; Rats, Inbred Strains; Trifluoperazine | 1983 |
Hemodynamic changes associated with long-term antihypertensive therapy with new calcium antagonist.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Hemodynamics; Humans; Long-Term Care; Male; Middle Aged; Nicardipine; Nifedipine; Vascular Resistance; Vasodilator Agents | 1983 |
Changes in systemic redistribution of blood flow by vasodilators.
Topics: Animals; Blood Circulation; Blood Gas Analysis; Blood Pressure; Cardiac Output; Chlorpromazine; Dogs; Heart Rate; Microspheres; Myocardium; Necrosis; Nicardipine; Nifedipine; Nitroglycerin; Vasodilator Agents | 1984 |
[Antihypertensives and the prevention of development of genetic hypertension in the hypertensive SHR rat].
Topics: Animals; Antihypertensive Agents; Atenolol; Captopril; Cardiomegaly; Dihydralazine; Dose-Response Relationship, Drug; Hydrochlorothiazide; Hypertension; Male; Nicardipine; Nifedipine; Prazosin; Rats; Rats, Inbred Strains; Time Factors; Vasodilator Agents | 1980 |
Low density lipoprotein-lowering and high density lipoprotein-elevating effects of nicardipine in rats.
Topics: Acetates; Animals; Cholesterol; Clofibrate; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Sterols | 1984 |
Haemodynamic effects of nicardipine hydrochloride. Studies during its use to control acute hypertension in anaesthetized patients.
Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, General; Female; Hemodynamics; Humans; Hypertension; Intraoperative Period; Male; Middle Aged; Nicardipine; Nifedipine; Vasodilator Agents | 1984 |
Effect of nicardipine in a hypertensive patient with diabetes mellitus.
Topics: Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 1; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Renal Circulation | 1984 |
Effects of nicardipine and other Ca2+-antagonists on catecholamine transport into chromaffin granule membrane vesicles.
Topics: Animals; Biological Transport; Calcium Channel Blockers; Catecholamines; Cattle; Chromaffin Granules; Chromaffin System; Diltiazem; In Vitro Techniques; Intracellular Membranes; Nicardipine; Nifedipine; Norepinephrine | 1984 |
Effects of nicardipine, nifedipine, verapamil, and diltiazem on urine volume, sodium and potassium excretion and plasma aldosterone levels in the rat.
Topics: Aldosterone; Animals; Calcium Channel Blockers; Diltiazem; Kidney; Male; Natriuresis; Nicardipine; Nifedipine; Potassium; Rats; Rats, Inbred WKY; Urine; Verapamil | 1984 |
In vitro effects of nicardipine on vascular and cardiac muscle preparations.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Coronary Vessels; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Nicardipine; Nifedipine; Papaverine; Rabbits; Vascular Resistance; Vasodilation; Verapamil | 1984 |
[Effects of Ca++-antagonist (nicardipine) on advanced A-V block--efficacy of Ca++-antagonists].
Topics: Aged; Calcium Channel Blockers; Heart Block; Humans; Male; Nicardipine; Nifedipine | 1984 |
Ineffectiveness of Ca2+-antagonists nicardipine and diltiazem on experimental atherosclerosis in cholesterol-fed rabbits.
Topics: Animals; Aorta; Arteriosclerosis; Benzazepines; Calcium; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Diltiazem; Kidney; Liver; Male; Nicardipine; Nifedipine; Phospholipids; Rabbits; Triglycerides | 1984 |
A high-performance liquid chromatographic method for the simultaneous determination of nicardipine and its pyridine metabolite II in plasma.
Topics: Biotransformation; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Nicardipine; Nifedipine; Pyridines | 1984 |
Effects of nicardipine and nisoldipine on myocardial metabolism, coronary blood flow and oxygen supply in angina pectoris.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Coronary Circulation; Hemodynamics; Humans; Lactates; Male; Middle Aged; Myocardium; Nicardipine; Nifedipine; Nisoldipine; Oxygen Consumption | 1984 |
Haemodynamic dose-response effects of i.v. nicardipine in coronary artery disease.
Topics: Adult; Calcium Channel Blockers; Coronary Disease; Dose-Response Relationship, Drug; Heart; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Nicardipine; Nifedipine; Physical Exertion | 1984 |
Chronotropic, dromotropic and inotropic effects of dilazep in the intact dog heart and isolated atrial preparation.
Topics: Animals; Azepines; Blood Pressure; Dilazep; Dogs; Female; Heart Atria; Heart Conduction System; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Nicardipine; Nifedipine; Partial Pressure; Sinoatrial Node | 1984 |
[Sustained-release pellet of vasodilators--basic experiment].
Topics: Delayed-Action Preparations; Diltiazem; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nicardipine; Nifedipine; Papaverine; Rupture, Spontaneous; Silicone Elastomers; Subarachnoid Hemorrhage; Temperature | 1984 |
Specificity of anti-leukotriene actions of nicardipine.
Topics: Animals; Cats; Coronary Vessels; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; SRS-A; Trachea; Vasoconstriction | 1984 |
[Effects of magnesium and nicardipine in the cardioplegic solution on the coronary arteries and myocardium].
Topics: Animals; Body Fluids; Calcium Channel Blockers; Coronary Vessels; Dogs; Heart; Heart Arrest, Induced; In Vitro Techniques; Ions; Magnesium; Myocardium; Nicardipine; Nifedipine; Perfusion; Potassium; Potassium Compounds; Rats; Rats, Inbred Strains; Vasodilator Agents | 1984 |
Immediate and longer-term effects of nicardipine, at rest and during exercise, in patients with coronary artery disease.
Topics: Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Physical Exertion; Vascular Resistance | 1984 |
Effects of nicardipine or nifedipine added to propranolol in patients with coronary artery disease.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Nicardipine; Nifedipine; Propranolol | 1984 |
Haemodynamic effects of nicardipine in acute myocardial infarction.
Topics: Blood Pressure; Calcium Channel Blockers; Cardiac Output; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infarction; Nicardipine; Nifedipine; Stroke Volume; Time Factors; Vascular Resistance | 1984 |
Intravenous nicardipine in patients with chronic heart failure: a nuclear stethoscope study.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Heart Failure; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Contraction; Nicardipine; Nifedipine | 1984 |
Pharmacokinetics of nicardipine following oral and intravenous administration in man.
Topics: Administration, Oral; Biological Availability; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Food; Humans; Injections, Intravenous; Kinetics; Male; Nicardipine; Nifedipine; Time Factors | 1984 |
Effects of calcium antagonists on central pressor and dipsogenic activities of angiotensin II in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Drinking; Drug Interactions; Injections, Intraventricular; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1984 |
Early operation of aneurysmal subarachnoid hemorrhage--use of nicardipine, a calcium channel blocker.
Topics: Adult; Aged; Calcium Channel Blockers; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Nicardipine; Nifedipine; Rupture, Spontaneous; Subarachnoid Hemorrhage | 1984 |
[Combination chemotherapy of nicardipine and vindesine sulfate, cis-diammine dichloroplatinum (II) for patients with advanced esophageal carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Calcium Channel Blockers; Carcinoma, Squamous Cell; Circadian Rhythm; Cisplatin; Drug Administration Schedule; Drug Resistance; Drug Synergism; Esophageal Neoplasms; Female; Humans; Infusions, Parenteral; Male; Middle Aged; Nicardipine; Nifedipine; Vinblastine; Vindesine | 1984 |
Comparison of the effects of nicardipine and nifedipine on isolated human myometrium.
Topics: Adult; Calcium Channel Blockers; Dinoprost; Female; Humans; Myometrium; Nicardipine; Nifedipine; Oxytocin; Potassium; Pregnancy; Prostaglandins F; Time Factors; Uterine Contraction | 1983 |
[Flow cytometric study of enhanced effect of anti-cancer drugs induced by nicardipine hydrochloride].
Topics: Animals; Brain Neoplasms; Cell Division; Cells, Cultured; DNA, Neoplasm; Doxorubicin; Flow Cytometry; Glioma; Interphase; Methylnitrosourea; Nicardipine; Nifedipine; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Vincristine | 1984 |
Calcium influx mediated vasoconstriction: studies in patients with mild and moderate essential hypertension.
Topics: Adult; Blood Pressure; Calcium; Calcium Channel Blockers; Forearm; Humans; Hypertension; Middle Aged; Muscles; Nicardipine; Nifedipine; Regional Blood Flow; Vascular Resistance; Vasoconstriction; Verapamil | 1983 |
Effects of five different organic calcium antagonists on guinea-pig isolated trachea.
Topics: Animals; Anti-Arrhythmia Agents; Bepridil; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicardipine; Nifedipine; Pyrrolidines; Trachea; Verapamil | 1984 |
[Membrane transport of anticancer drugs--potentiation of antitumor effect by calcium modifiers and overcoming of drug-resistance].
Topics: Animals; Antineoplastic Agents; Biological Transport; Calcium Channel Blockers; Calcium-Binding Proteins; Calmodulin; Drug Resistance; Drug Synergism; Mice; Neoplasms, Experimental; Nicardipine; Nifedipine; Pyridines | 1983 |
Interaction between digoxin and the calcium antagonists nicardipine and tiapamil.
Topics: Aged; Calcium Channel Blockers; Digoxin; Drug Interactions; Electrocardiography; Female; Humans; Male; Nicardipine; Nifedipine; Potassium; Propylamines; Tiapamil Hydrochloride; Time Factors | 1983 |
[Electrophysiological effects of nicardipine hydrochloride (YC-93) on the human cardiac condition system].
Topics: Adolescent; Adult; Aged; Calcium Channel Blockers; Female; Heart Block; Heart Conduction System; Humans; Male; Middle Aged; Nicardipine; Nifedipine | 1983 |
[Combination therapy of vinca alkaloids and nicardipine in non-Hodgkin's lymphoma with resistant to various antineoplastic agents].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance; Drug Therapy, Combination; Female; Humans; Lymphoma; Male; Mitomycin; Mitomycins; Nicardipine; Nifedipine; Progesterone; Recurrence; Vinblastine; Vinca Alkaloids | 1983 |
[Effects of nicardipine hydrochloride on hemodynamics and regional myocardial functions in experimental coronary ischemia].
Topics: Animals; Calcium Channel Blockers; Dogs; Hemodynamics; Myocardial Contraction; Myocardial Infarction; Nicardipine; Nifedipine | 1983 |
[Protective effect of nicardipine hydrochloride on the perfused ischemic canine myocardium].
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Myocardium; Nicardipine; Nifedipine; Nucleotides, Cyclic | 1983 |
The effect of a new calcium channel blocker nicardipine on 24-hour ambulatory blood pressure and the pressor response to isometric and dynamic exercise.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Isometric Contraction; Male; Middle Aged; Muscle Contraction; Nicardipine; Nifedipine; Physical Exertion; Posture; Time Factors | 1983 |
The beneficial effect of nicardipine compared with nifedipine and verapamil in limiting myocardial infarct size in baboons.
Topics: Animals; Calcium Channel Blockers; Female; Hemodynamics; Lidocaine; Male; Myocardial Infarction; Nicardipine; Nifedipine; Nitroblue Tetrazolium; Papio; Pyridines; Verapamil | 1983 |
The beneficial effect of nicardipine on the healing of myocardial infarcts in dogs.
Topics: Animals; Blood Pressure; Dogs; Hemodynamics; Male; Myocardial Infarction; Myocardium; Nicardipine; Nifedipine; Papillary Muscles | 1983 |
Baroreflex setting and sensitivity after acute and chronic nicardipine therapy.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Pressoreceptors; Reflex | 1984 |
Assessment of regional left ventricular relaxation in patients with coronary artery disease: importance of geometric factors and changes in wall thickness.
Topics: Adult; Aged; Coronary Disease; Heart Ventricles; Humans; Middle Aged; Muscle Relaxation; Nicardipine; Nifedipine | 1984 |
[Calcium antagonists in the management of hypertension].
Topics: Aged; Calcium Channel Blockers; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Verapamil | 1984 |
Effects of Ca antagonists on the norepinephrine release and contractile responses of isolated canine saphenous veins to transmural nerve stimulation.
Topics: Adrenergic Fibers; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nerve Endings; Nicardipine; Nifedipine; Norepinephrine; Saphenous Vein; Tritium; Verapamil | 1984 |
[The effects of Ca++ antagonists nifedipine and nicardipine on slow reacting substance of anaphylaxis (SRS-A) mediated bronchoconstriction in guinea pig].
Topics: Animals; Asthma; Calcium Channel Blockers; Depression, Chemical; Guinea Pigs; Male; Mast Cells; Nicardipine; Nifedipine; SRS-A | 1984 |
Antihypertensive and renal effects of nicardipine.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Glomerular Filtration Rate; Headache; Humans; Hypertension; Kidney Function Tests; Male; Middle Aged; Natriuresis; Nicardipine; Nifedipine | 1984 |
Antihypertensive effect of nicardipine hydrochloride in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Pulse; Pyridines; Renin; Time Factors | 1982 |
Dihydropyridines as potent calcium channel blockers in neuronal cells.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Calcium Channel Blockers; Calcium Chloride; Chick Embryo; Clone Cells; Neoplasms, Experimental; Neurons; Nicardipine; Nifedipine; Norepinephrine; Pheochromocytoma; Potassium; Pyridines; Rats; Retina | 1983 |
Effect of Ca-antagonists on the contraction of cerebral and peripheral arteries produced by electrical and mechanical stimuli.
Topics: Animals; Arteries; Calcium Channel Blockers; Cerebral Arteries; Dogs; Electric Stimulation; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Rabbits | 1983 |
Calcium antagonist and the peripheral circulation: differences and similarities between PY 108-068, nicardipine, verapamil and diltiazem.
Topics: Animals; Calcium Channel Blockers; Cats; Diltiazem; Hemodynamics; Microspheres; Neural Conduction; Nicardipine; Nifedipine; Regional Blood Flow; Verapamil | 1983 |
Electrophysiological effects of nicardipine hydrochloride on the isolated sinoatrial and atrioventricular nodes of the rabbit.
Topics: Animals; Atrioventricular Node; Calcium Channel Blockers; Dose-Response Relationship, Drug; Heart Conduction System; In Vitro Techniques; Microelectrodes; Nicardipine; Nifedipine; Pyridines; Rabbits; Refractory Period, Electrophysiological; Sinoatrial Node | 1983 |
The action of the ionophore ionomycin in guinea-pig intestinal smooth muscle.
Topics: Animals; Cadmium; Calcium; Ethers; Gallopamil; Guinea Pigs; Ileum; Ionomycin; Manganese; Muscle, Smooth; Nicardipine; Nifedipine; Sodium | 1983 |
[Effect of nicardipine (YC-93), a calcium antagonist, on hormonal secretion of the pancreas (author's transl)].
Topics: Animals; Calcium; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Male; Nicardipine; Nifedipine; Pancreas; Pyridines; Rats | 1981 |
Deactivation of the uterus during normal and premature labor by the calcium antagonist nicardipine.
Topics: Animals; Calcium Channel Blockers; Female; Labor, Obstetric; Nicardipine; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pyridines; Rabbits; Rats; Rats, Inbred Strains; Uterine Contraction; Vasodilator Agents | 1982 |
Calcium channel blockers in chronic stable angina. A review.
Topics: Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Diltiazem; Electrocardiography; Humans; Nicardipine; Nifedipine; Verapamil | 1982 |
Vasodilator and hypotensive effects of the optical isomers of nicardipine (YC-93), a new Ca2+-antagonist.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Dose-Response Relationship, Drug; Female; Isomerism; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Nicardipine; Nifedipine; Pyridines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Vasodilator Agents; Vertebral Artery | 1982 |
Effects of nicardipine, a new dihydropyridine vasodilator, on coronary circulation and ischemia-induced conduction delay in dogs.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Dogs; Electrophysiology; Female; Heart Conduction System; Male; Nicardipine; Nifedipine; Pyridines; Vasodilator Agents; Verapamil | 1982 |
Metabolic fate of nicardipine hydrochloride, a new vasodilator, by various species in vitro.
Topics: Animals; Biotransformation; Blood Proteins; Dogs; In Vitro Techniques; Kinetics; Macaca mulatta; Male; Microsomes, Liver; Nicardipine; Nifedipine; Protein Binding; Pyridines; Rats; Species Specificity; Vasodilator Agents | 1980 |
Inhibition of calcium influx in rabbit aorta by nicardipine hydrochloride (YC-93).
Topics: Animals; Aorta, Thoracic; Biological Transport; Calcium; In Vitro Techniques; Lanthanum; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Potassium; Pyridines; Rabbits; Vasodilator Agents; Verapamil | 1981 |
Specific determination of plasma nicardipine hydrochloride levels by gas chromatography-mass spectrometry.
Topics: Animals; Dogs; Gas Chromatography-Mass Spectrometry; Humans; Hypertension; Nicardipine; Nifedipine; Pyridines; Rats; Reference Values; Time Factors | 1981 |
Effects of nicardipine on the cross-perfused canine atrium.
Topics: Anesthesia; Animals; Chlorides; Dogs; Female; Heart; Heart Rate; Male; Manganese; Manganese Compounds; Myocardial Contraction; Nicardipine; Nifedipine; Perfusion; Pyridines; Vasodilator Agents; Verapamil | 1981 |
[Effects of intravenous nicardipine hydrochloride (YC 93), a calcium antagonist, on renal function (author's transl)].
Topics: Glomerular Filtration Rate; Humans; Hypertension; Injections, Intravenous; Kidney; Nicardipine; Nifedipine; Pyridines; Renal Circulation | 1981 |
Comparative pharmacokinetics of nicardipine hydrochloride, a new vasodilator, in various species.
Topics: Administration, Oral; Adult; Animals; Dogs; Female; Humans; Injections, Intravenous; Kinetics; Macaca mulatta; Male; Nicardipine; Nifedipine; Pyridines; Rats; Species Specificity; Vasodilator Agents | 1980 |
Application of the stable isotope technique to the elucidation of the saturation phenomenon of nicardipine hydrochloride metabolizing enzyme activity in dogs.
Topics: Animals; Deuterium; Dogs; Gas Chromatography-Mass Spectrometry; Kinetics; Liver; Male; Nicardipine; Nifedipine; Pyridines; Vasodilator Agents | 1980 |
Leukotriene C4-stimulated contractions in bullfrog lung are affected by cold acclimation and calcium antagonists.
Topics: Acclimatization; Animals; Caffeine; Calcium Channel Blockers; Calcium-Transporting ATPases; Cold Temperature; Contracture; Egtazic Acid; Eicosapentaenoic Acid; Female; Hot Temperature; Leukotriene C4; Lung; Male; Nicardipine; Nifedipine; Nitrendipine; Rana catesbeiana; SRS-A; Terpenes; Thapsigargin; Verapamil | 1995 |
Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; DNA; Heart Rate; Hypertension; Male; Myocardium; Nicardipine; Nifedipine; Organ Size; Propranolol; Rats; Rats, Inbred SHR; Renin; RNA | 1993 |
Nifedipine and nicardipine potentiate glucagon-stimulated glycogenolysis in primary cultures of rat hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Glycogen; Liver; Male; Nicardipine; Nifedipine; Papaverine; Rats; Rats, Wistar | 1993 |
Extracellular calcium causes the release of calcium from intracellular stores in chick osteocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Chick Embryo; Cytosol; Gallic Acid; Nicardipine; Nifedipine; Osteocytes | 1995 |
Effects of the novel water-soluble calcium antagonist (+/-)-3-(4-allyl-1-piperazinyl)-2,2-dimethylpropyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate dihydrochloride on the responses of isolated canine arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Dogs; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Norepinephrine; Potassium Chloride; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Antihypertensive effects of AJ-2615, a new calcium antagonist with alpha 1-adrenergic blocking activity in experimental hypertensive animals.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Dibenzothiepins; Diltiazem; Dogs; Female; Heart Rate; Hypertension; Hypertension, Renovascular; Male; Nicardipine; Nifedipine; Piperazines; Rats; Rats, Inbred SHR; Rats, Wistar | 1993 |
Dihydropyridine-sensitive calcium current mediates neurotransmitter release from bipolar cells of the goldfish retina.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Fura-2; Goldfish; In Vitro Techniques; Kinetics; Neurons; Nicardipine; Nifedipine; omega-Conotoxins; Peptides; Retina | 1993 |
Potentiation of isoproterenol-stimulated gluconeogenesis in serum-free cultures of rat hepatocytes by nifedipine and nicardipine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Channel Blockers; Cells, Cultured; Culture Media, Serum-Free; Cyclic AMP; Drug Synergism; Gluconeogenesis; Isoproterenol; Lactates; Lactic Acid; Liver; Male; Nicardipine; Nifedipine; Rats; Rats, Wistar | 1993 |
Influences of the calcium antagonists nicardipine and nifedipine, and the calcium agonist BAY-K-8644, on the pharmacokinetics of propranolol in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Administration, Oral; Animals; Biological Availability; Calcium Channel Agonists; Calcium Channel Blockers; Drug Interactions; Injections, Intravenous; Male; Nicardipine; Nifedipine; Propranolol; Rats; Rats, Wistar | 1993 |
Investigation and optimisation of the use of micellar electrokinetic chromatography for the analysis of six cardiovascular drugs.
Topics: Amlodipine; Atenolol; Cardiovascular Agents; Chromatography; Diltiazem; Electrochemistry; Hydrogen-Ion Concentration; Kinetics; Micelles; Nicardipine; Nifedipine; Osmosis; Sodium Dodecyl Sulfate; Verapamil | 1995 |
The effects of calcium antagonists and prostaglandin E1 on isolated canine coronary arterial tension.
Topics: Alprostadil; Animals; Calcium; Calcium Channel Blockers; Coronary Vessels; Data Interpretation, Statistical; Diltiazem; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Potassium; Sodium; Solutions; Verapamil | 1994 |
Antioxidant activity of calcium channel blocking drugs.
Topics: Animals; Antioxidants; Aorta; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Diltiazem; Dogs; Endothelium, Vascular; Free Radicals; Glutathione; Heart Ventricles; Isomerism; Kinetics; Lipid Peroxidation; Malondialdehyde; Myocardium; Nicardipine; Nifedipine; Sarcolemma; Verapamil | 1994 |
Inhibitor effects of diltiazem, nicardipine, nifedipine and verapamil on the norepinephrine-induced contractions of the canine saphenous vein in calcium-free medium.
Topics: Animals; Calcium; Calcium Channel Blockers; Culture Media; Diltiazem; Dogs; Electrophysiology; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Norepinephrine; Saphenous Vein; Verapamil | 1994 |
[Effects of calcium antagonists on prostaglandin E2 production in cultured human amnion cells].
Topics: Amnion; Calcium Channel Blockers; Cells, Cultured; Depression, Chemical; Diltiazem; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Female; Humans; Interleukin-1; Nicardipine; Nifedipine; Phospholipases A; Phospholipases A2; Pregnancy; Verapamil | 1994 |
A mathematical model for dynamics of cardiovascular drug action: application to intravenous dihydropyridines in healthy volunteers.
Topics: Adult; Baroreflex; Blood Pressure; Cardiac Output; Cardiovascular Agents; Dihydropyridines; Heart Rate; Hemodynamics; Humans; Infusions, Intravenous; Male; Models, Theoretical; Nicardipine; Nifedipine; Pressoreceptors; Retrospective Studies; Vascular Resistance | 1993 |
Effects of dihydropyridines on cerebral blood vessels.
Topics: Administration, Oral; Blood Pressure; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine | 1993 |
Metal ions affect neuronal membrane fluidity of rat cerebral cortex.
Topics: Animals; Cations; Cerebral Cortex; Cyclic N-Oxides; Edetic Acid; Egtazic Acid; Electron Spin Resonance Spectroscopy; Flunarizine; Kinetics; Male; Membrane Fluidity; Metals; Neurons; Nicardipine; Nifedipine; Nimodipine; Rats; Rats, Sprague-Dawley; Spin Labels; Synaptosomes | 1994 |
The nicardipine-isoprenaline interaction in human and guinea-pig isolated airways.
Topics: Adenosine; Animals; Bronchi; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Humans; Isoproterenol; Male; Muscle Relaxation; Nicardipine; Nifedipine; Nitroprusside; Theophylline; Trachea | 1994 |
[Effect of Ca-antagonists on pulmonary blood flow during single-lung ventilation in the dog].
Topics: Animals; Calcium Channel Blockers; Cardiac Output; Dogs; Nicardipine; Nifedipine; Oxygen; Pulmonary Artery; Pulmonary Circulation; Respiration; Vasoconstriction | 1993 |
Effects of vasoactive intestinal contractor on voltage-activated Ca2+ currents in feline parasympathetic neurons.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Action Potentials; Animals; Calcium Channels; Cats; Colon; Electrophysiology; Endothelins; Female; Ganglia, Parasympathetic; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Kinetics; Male; Membrane Potentials; Muscle, Smooth; Neurons; Nicardipine; Nifedipine; Peptides; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1993 |
Effect of benidipine hydrochloride (KW-3049), on cerebral ischemia induced by bilateral occlusion of the common carotid arteries in rats.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Brain; Brain Chemistry; Brain Ischemia; Calcium Channel Blockers; Carotid Artery, Common; Dihydropyridines; Lactates; Lactic Acid; Male; Nicardipine; Nifedipine; Phosphocreatine; Potassium; Rats; Rats, Wistar; Sodium; Verapamil | 1993 |
[Clinical study of total intravenous anesthesia with droperidol, fentanyl and ketamine--effects of nicardipine, diltiazem and nifedipine on intraoperative hypertension].
Topics: Anesthesia, Intravenous; Calcium Channel Blockers; Diltiazem; Droperidol; Female; Fentanyl; Humans; Hypertension; Intraoperative Complications; Ketamine; Male; Middle Aged; Nicardipine; Nifedipine | 1993 |
Investigation of the inhibition of complement mediated cell death.
Topics: 3T3 Cells; Animals; Calcium Channel Blockers; Cell Death; Chlorpromazine; Cinnarizine; Complement Inactivator Proteins; Complement Membrane Attack Complex; Mice; Nicardipine; Nifedipine | 1996 |
Calcium channel blockers induce thymic apoptosis in vivo in rats.
Topics: Animals; Apoptosis; Calcium Channel Blockers; Chlorpromazine; Diltiazem; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Hydrocortisone; Hypotension; Image Processing, Computer-Assisted; Injections, Intraperitoneal; Male; Microscopy, Electron; Nicardipine; Nifedipine; Nitroprusside; Organ Size; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; T-Lymphocytes; Thymus Gland; Verapamil | 1996 |
Mediation of iron uptake and release in erythroid cells by photodegradation products of nifedipine.
Topics: Animals; Dose-Response Relationship, Drug; Erythrocytes; Hydrogen-Ion Concentration; Iron; Nicardipine; Nifedipine; Rabbits; Reticulocytes; Time Factors | 1996 |
[Effect of cilnidipine on renal function in SHR and endothelin-induced renal dysfunction].
Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Dihydropyridines; Diuresis; Endothelins; Hypertension; Male; Natriuresis; Nicardipine; Nifedipine; Rats; Rats, Inbred SHR; Renal Circulation | 1996 |
Ca2+ channel blockade and the antielectroshock activity of NMDA receptor antagonists, CGP 40116 and CGP 43487, in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Excitatory Amino Acid Antagonists; Flunarizine; Male; Mice; Nicardipine; Nifedipine; Receptors, N-Methyl-D-Aspartate | 1996 |
Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Diltiazem; Felodipine; Fumarates; Heart; Iron; Lipid Peroxidation; Male; Myocardium; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Verapamil | 1996 |
Nicardipine and nifedipine inhibit fatty acid desaturases in rat liver microsomes.
Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Delta-5 Fatty Acid Desaturase; Enzyme Inhibitors; Fatty Acid Desaturases; Kinetics; Linear Models; Linoleoyl-CoA Desaturase; Male; Microsomes, Liver; Mucorales; Nicardipine; Nifedipine; Rats; Rats, Wistar | 1996 |
Anticonvulsant and adverse effects of MK-801, LY 235959, and GYKI 52466 in combination with Ca2+ channel inhibitors in mice.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Avoidance Learning; Benzodiazepines; Calcium Channel Blockers; Dizocilpine Maleate; Drug Interactions; Electroshock; Excitatory Amino Acid Antagonists; Flunarizine; Isoquinolines; Male; Mice; Motor Activity; Nicardipine; Nifedipine; Seizures | 1997 |
Effect of nilvadipine on high-voltage activated Ca2+ channels in rat CNS neurons.
Topics: Animals; Brain; Cadmium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; In Vitro Techniques; Kinetics; Membrane Potentials; Nerve Tissue Proteins; Neurons; Nicardipine; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Rats; Rats, Wistar; Spider Venoms | 1997 |
pH dependent binding of ligands to serum lipoproteins.
Topics: Hydrogen-Ion Concentration; Indoles; Lipoproteins; Nicardipine; Nifedipine; Protein Binding; Spectrum Analysis | 1997 |
A comparison of the uricosuric effects in rats of diltiazem and derivatives of dihydropyridine (nicardipine and nifedipine).
Topics: Animals; Blood Pressure; Diltiazem; Heart Rate; Inulin; Male; Nicardipine; Nifedipine; Rats; Rats, Wistar; Renal Circulation; Uric Acid; Uricosuric Agents; Urodynamics | 1997 |
[The role of Ca2+ in the pathogenesis of human pituitary GH-secreting adenomas].
Topics: Adenoma; Biological Transport, Active; Calcimycin; Calcium; Calcium Channel Blockers; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Ionophores; Nicardipine; Nifedipine; Octreotide; Pituitary Neoplasms; Somatostatin; Tumor Cells, Cultured | 1996 |
Effects of dihydropyridine Ca2+ channel blockers on the discriminative stimulus and the motor impairing effects of (+/-)-Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Discrimination, Psychological; Male; Mice; Motor Activity; Nicardipine; Nifedipine; Nimodipine | 1997 |
The role of calcium ion in the pathogenesis of human pituitary GH-secreting adenomas.
Topics: Adenoma; Biological Transport, Active; Calcium; Calcium Channel Blockers; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Nicardipine; Nifedipine; Octreotide; Pituitary Neoplasms; Somatostatin; Tumor Cells, Cultured | 1996 |
Differentiation of the inhibitory effects of calcium antagonists on abnormal behaviors induced by methamphetamine or phencyclidine.
Topics: Amygdala; Animals; Behavior, Animal; Calcium Channel Blockers; Caudate Nucleus; Central Nervous System Stimulants; Dopamine Uptake Inhibitors; Flunarizine; Injections, Intraperitoneal; Male; Methamphetamine; Microinjections; Motor Activity; Nicardipine; Nifedipine; Phencyclidine; Putamen; Rats; Rats, Wistar | 1998 |
Nilvadipine inhibits acute rise of aqueous flare and intraocular pressure induced by prostaglandin E2 in pigmented rabbits.
Topics: Animals; Anterior Eye Segment; Aqueous Humor; Calcium Channel Blockers; Dinoprostone; Dose-Response Relationship, Drug; Eye Proteins; Injections, Intravenous; Intraocular Pressure; Male; Nicardipine; Nifedipine; Ophthalmic Solutions; Rabbits; Tonometry, Ocular | 1998 |
Rational use of calcium-channel antagonists in Raynaud's phenomenon.
Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Humans; Isradipine; Nicardipine; Nifedipine; Raynaud Disease | 1998 |
A calcium agonist, Bay k 8644, suppresses the embryotoxic effects induced by dihydropyridines calcium channel blockers in cultured rat embryos.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Culture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Male; Nicardipine; Nifedipine; Nitrendipine; Rats; Rats, Sprague-Dawley | 1998 |
Effects of excess K+ on carbachol-induced contractions in the guinea-pig tracheal muscle.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Drug Combinations; Guinea Pigs; Muscle Contraction; Muscle Tonus; Nicardipine; Nifedipine; Osmolar Concentration; Potassium; Trachea | 1998 |
The effects of nickel and cobalt ions on the spontaneous electrical activity, slow wave, in the circular muscle of the guinea-pig gastric antrum.
Topics: Animals; Calcium; Cobalt; Electrophysiology; Guinea Pigs; In Vitro Techniques; Ions; Muscle, Smooth; Nicardipine; Nickel; Nifedipine; Pyloric Antrum | 1998 |
Neuroprotective effects of a dihydropyridine derivative, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarbox ylic acid methyl 6-(5-phenyl-3-pyrazolyloxy)hexyl ester (CV-159), on rat ischemic brain injury.
Topics: Animals; Body Temperature; Brain Edema; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cerebral Infarction; Dihydropyridines; Hemodynamics; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Neuroprotective Agents; Nicardipine; Nifedipine; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors; Water | 1999 |
Effects of long-acting versus short-acting calcium channel blockers among older survivors of acute myocardial infarction.
Topics: Aged; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Female; Humans; Male; Myocardial Infarction; Nicardipine; Nifedipine; Proportional Hazards Models; Retrospective Studies; Risk; Survival Analysis; Survivors; Verapamil | 1999 |
Effects of some 1,4-dihydropyridine Ca antagonists on the blast transformation of rat spleen lymphocytes.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Lymphocyte Activation; Nicardipine; Nifedipine; Nimodipine; Rats; Spleen | 1999 |
Nicardipine inhibits N-type calcium channels in dbcAMP-differentiated neuroblastoma x glioma hybrid cells (NG 108-15 cells).
Topics: Bucladesine; Calcium Channel Blockers; Calcium Channels; Cell Transformation, Neoplastic; Glioma; Humans; Hybrid Cells; Neuroblastoma; Nicardipine; Nifedipine; Tumor Cells, Cultured | 1999 |
Effect of calcium channel antagonists nifedipine and nicardipine on rat cytochrome P-450 2B and 3A forms.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Calcium Channel Blockers; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Enzyme Induction; Isoenzymes; Liver; Male; Nicardipine; Nifedipine; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases | 1999 |
Eicosapentaenoic acid inhibits vasopressin-activated Ca2+ influx and cell proliferation in rat aortic smooth muscle cell lines.
Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Division; Cells, Cultured; Eicosapentaenoic Acid; Ion Pumps; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Rats; Vasoconstrictor Agents; Vasopressins | 1999 |
Comparative study on calcium channel antagonists in the human radial artery: clinical implications.
Topics: Analysis of Variance; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nicardipine; Nifedipine; Radial Artery; Vasodilator Agents; Verapamil | 2000 |
Effect of benidipine on depolarizing stimulation-induced increase of intracellular calcium concentration in cultured mouse hippocampal neurons.
Topics: Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Electric Stimulation; Hippocampus; Mice; Neurons; Nicardipine; Nifedipine | 1999 |
Appearance of highly sensitive cells to L-type Ca antagonist in cultured cerebellar granule cells.
Topics: Animals; Calcium; Cell Adhesion; Cells, Cultured; Cerebellum; Image Cytometry; Nicardipine; Nifedipine; Nimodipine; Polylysine; Rats; Rats, Wistar | 1999 |
Pharmacological characterization of a novel AVP(4-9) binding site in rat hippocampus.
Topics: Animals; Arginine Vasopressin; Binding, Competitive; Calcium; Calcium Channel Blockers; Hippocampus; Inositol 1,4,5-Trisphosphate; Male; Memory; Nicardipine; Nifedipine; omega-Conotoxins; Peptide Fragments; Radioligand Assay; Rats; Rats, Wistar; Signal Transduction; Sulfur Radioisotopes | 2000 |
Altered beta-adrenoceptor-mediated responses in the gastric smooth muscle of hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Colforsin; Electrophysiology; Gastric Emptying; Gastric Fundus; Gastric Mucosa; Hypertension; Isoproterenol; Male; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta | 2000 |
Human umbilical vein endothelial cells (HUVECs) show Ca(2+) mobilization as well as Ca(2+) influx upon hypoxia.
Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Egtazic Acid; Endothelium, Vascular; Estrenes; Female; Humans; Hypoxia; Microscopy, Confocal; Nicardipine; Nicotine; Nifedipine; Pyrrolidinones; Type C Phospholipases; Umbilical Veins | 2000 |
Inhibition by nifedipine of adherence- and activated macrophage-induced death of human gingival fibroblasts.
Topics: Animals; Calcium Channel Blockers; Cell Adhesion; Cell Death; Cell Division; Cell Line; Cells, Cultured; Coculture Techniques; Diltiazem; DNA Fragmentation; Dose-Response Relationship, Drug; Fibroblasts; Gingiva; Humans; Lipopolysaccharides; Macrophages; Nicardipine; Nifedipine; Nitric Oxide; Nitric Oxide Donors; Thymidine; Time Factors; Verapamil | 2001 |
Dihydropyridine calcium channel blockers inhibit ascorbic acid accumulation in human intestinal Caco-2 cells.
Topics: Ascorbic Acid; Caco-2 Cells; Calcium Channel Blockers; Diethylstilbestrol; Genistein; Humans; Nicardipine; Nifedipine; Sodium Channels | 2001 |
The use of short-acting nifedipine in children with hypertension: another example of the need for comprehensive drug testing in children.
Topics: Age Factors; Antihypertensive Agents; Child; Clinical Trials as Topic; Humans; Hypertension; Nicardipine; Nifedipine | 2001 |
Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Chloride Channels; Dihydropyridines; Drug Interactions; Glycine; Neural Inhibition; Neurons; Nicardipine; Nifedipine; Nitrendipine; Rats; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Synaptic Transmission; Verapamil | 2001 |
Reversal of preexisting vasospasm in coronary artery conduits.
Topics: Arteries; Calcium Channel Blockers; Coronary Artery Bypass; Coronary Disease; Culture Techniques; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Graft Occlusion, Vascular; Humans; Nicardipine; Nifedipine; Nitroglycerin; Vasoconstriction; Vasodilation; Veins; Verapamil | 2001 |
Development of hollow microspheres as floating controlled-release systems for cardiovascular drugs: preparation and release characteristics.
Topics: Algorithms; Antihypertensive Agents; Calorimetry, Differential Scanning; Cardiovascular Agents; Delayed-Action Preparations; Diffusion; Half-Life; Kinetics; Microscopy, Electron, Scanning; Microspheres; Nicardipine; Nifedipine; Particle Size; Solubility | 2001 |
Protective effects of dihydropyridine Ca-blockers against endothelial cell oxidative injury due to combined nitric oxide and superoxide.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cattle; Cell Survival; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Lipid Peroxidation; Molsidomine; Nicardipine; Nifedipine; Nisoldipine; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Superoxides; Thiobarbituric Acid Reactive Substances | 2002 |
Comparative study of calcium-channel blockers on cell proliferation, DNA and collagen syntheses, and EGF receptors of cultured gingival fibroblasts derived from human nifedipine, nicardipine and nisoldipine responders.
Topics: Adult; Aged; Analysis of Variance; Anticonvulsants; Calcium Channel Blockers; Cell Culture Techniques; Cell Division; Collagen; Diltiazem; DNA; ErbB Receptors; Female; Fibroblasts; Flow Cytometry; Gingiva; Gingival Overgrowth; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Nisoldipine; Phenytoin; Radiopharmaceuticals; Statistics as Topic; Tritium; Verapamil | 2001 |
Effect of the organotin compound triethyltin on Ca2+ handling in human prostate cancer cells.
Topics: Calcium; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Drug Antagonism; Fura-2; Humans; Male; Nicardipine; Nifedipine; Nimodipine; Prostatic Neoplasms; Thapsigargin; Triethyltin Compounds; Tumor Cells, Cultured | 2002 |
Influence of nicardipine and nifedipine on plasma carvedilol disposition after oral administration in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Calcium Channel Blockers; Carbazoles; Carvedilol; Chromatography, High Pressure Liquid; Drug Interactions; Male; Nicardipine; Nifedipine; Propanolamines; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
Relative effects of dihydropyridine L-type calcium channel antagonism on biliary, duodenal, and vascular tissues: an in vivo and in vitro analysis in Australian brush-tailed possum.
Topics: Animals; Blood Pressure; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Duodenum; Female; Gallbladder; Male; Manometry; Nicardipine; Nifedipine; Opossums; Sphincter of Oddi | 2002 |
Effects of three different L-type Ca2+ entry blockers on airway constriction induced by muscarinic receptor stimulation.
Topics: Animals; Bronchoconstriction; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Dogs; Dose-Response Relationship, Drug; Epinephrine; Female; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Norepinephrine; Receptors, Muscarinic; Trachea; Verapamil | 2003 |
Circumferential, not longitudinal, colonic stretch increases synaptic input to mouse prevertebral ganglion neurons.
Topics: Afferent Pathways; Animals; Colon; Excitatory Postsynaptic Potentials; Ganglia, Sympathetic; Male; Mechanoreceptors; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Neurons; Nicardipine; Nifedipine; Spine; Stress, Mechanical; Synapses | 2003 |
Study of drug effects of calcium channel blockers on retinal degeneration of rd mouse.
Topics: Animals; Calcium Channel Blockers; Caspases; Diltiazem; Electroretinography; Fibroblast Growth Factor 2; Gene Expression; Membrane Proteins; Mice; Mice, Mutant Strains; Microscopy, Electron; Nerve Tissue Proteins; Nicardipine; Nifedipine; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Retinitis Pigmentosa; Synaptogyrins | 2004 |
Inhibitory effects of carvedilol on calcium channels in vascular smooth muscle cells.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aorta; Calcium; Calcium Channels; Calcium Signaling; Carbazoles; Carvedilol; Cell Division; Endothelin-1; Metoprolol; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Propanolamines; Rats; Vasodilator Agents; Vasopressins | 2003 |
Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; beta-Cyclodextrins; Bucladesine; Calcium Channel Blockers; Cell Line; Cholesterol; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; Humans; Hydroxycholesterols; Lipoproteins; Lipoproteins, HDL; Liver X Receptors; Lovastatin; Macrophages; Mice; Nicardipine; Nifedipine; Orphan Nuclear Receptors; Phospholipids; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Stereoisomerism; Transfection; Verapamil | 2004 |
Sex difference in induction of hepatic CYP2B and CYP3A subfamily enzymes by nicardipine and nifedipine in rats.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Calcium Channel Blockers; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gene Expression Regulation, Enzymologic; Isoenzymes; Male; Microsomes, Liver; Nicardipine; Nifedipine; Oxidoreductases, N-Demethylating; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Factors; Steroid Hydroxylases; Transcriptional Activation | 2004 |
Induction of hepatic cyp2b and cyp3a subfamily enzymes by nicardipine and nifedipine in mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Calcium Channel Blockers; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gene Expression Regulation, Enzymologic; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Microsomes, Liver; Nicardipine; Nifedipine; Oxidoreductases; Oxidoreductases, N-Demethylating; Sex Factors; Steroid Hydroxylases | 2004 |
Intubation without premedication may worsen outcome for unconsciousness patients with intracranial hemorrhage.
Topics: Analgesics, Opioid; Anesthetics, Local; Anti-Anxiety Agents; Diazepam; Emergency Medicine; Female; Fentanyl; Glasgow Outcome Scale; Humans; Intracranial Hemorrhages; Intubation, Intratracheal; Lidocaine; Male; Middle Aged; Nicardipine; Nifedipine; Outcome and Process Assessment, Health Care; Pentazocine; Premedication; Retrospective Studies; Unconsciousness; Vasodilator Agents | 2005 |
Comment on the article "Acute pulmonary oedema during nicardipine therapy for premature labour. Report of five cases" by Vaast P., et al. [Eur J Obstet Gynecol Reprod Biol 2004;113:98-9].
Topics: Calcium Channel Blockers; Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pulmonary Edema | 2005 |
[Tocolysis with nifedipine: its use in current practice. Gynecol Obstet Fertil 2005;33:483-7].
Topics: Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome; Pulmonary Edema; Randomized Controlled Trials as Topic; Risk Factors; Tocolysis; Tocolytic Agents; Treatment Outcome | 2006 |
The calcium channel blockers, 1,4-dihydropyridines, are substrates of the multidrug resistance-linked ABC drug transporter, ABCG2.
Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Azides; Calcium Channel Blockers; Cell Line; Chlorophyll; Dihydropyridines; Drug Interactions; Humans; Mitoxantrone; Neoplasm Proteins; Nicardipine; Nifedipine; Photoaffinity Labels; Prazosin | 2006 |
Evidence for postsynaptic modulation of muscle contraction by a Drosophila neuropeptide.
Topics: Amiloride; Amino Acid Sequence; Animals; Calcium Channels, L-Type; Calcium Channels, T-Type; Dose-Response Relationship, Drug; Drosophila; Flunarizine; FMRFamide; Glutamic Acid; Larva; Molecular Sequence Data; Muscle Contraction; Nicardipine; Nifedipine; Receptors, Glutamate; Synaptic Transmission | 2008 |
Schistosoma mansoni: lack of correlation between praziquantel-induced intra-worm calcium influx and parasite death.
Topics: Animals; Anthelmintics; Benzodiazepinones; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cytochalasin D; Kinetics; Male; Mice; Nicardipine; Nifedipine; Nucleic Acid Synthesis Inhibitors; Praziquantel; Schistosoma mansoni; Schistosomicides | 2008 |
[Non-invasive ventilation for pulmonary edema associated with tocolytic agents during labour for a twin pregnancy].
Topics: Adult; Apgar Score; Delivery, Obstetric; Female; Humans; Infant, Newborn; Nicardipine; Nifedipine; Pleural Effusion; Pregnancy; Pulmonary Edema; Respiration, Artificial; Tocolytic Agents; Tomography, X-Ray Computed; Twins; Vasotocin | 2008 |
[Nifedipine or nicardipine in management of threatened preterm delivery: an observational population-based study].
Topics: Adult; Calcium Channel Blockers; Female; France; Humans; Nicardipine; Nifedipine; Pregnancy; Premature Birth; Randomized Controlled Trials as Topic; Tocolytic Agents; Treatment Outcome; Young Adult | 2010 |
Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracellular calcium levels by selected L-type calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Child; Drug Evaluation, Preclinical; Flunarizine; Humans; Intracellular Space; Membrane Glycoproteins; Molecular Chaperones; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Nicardipine; Nifedipine; Nimodipine; Potassium Chloride; RNA Interference; RNA, Small Interfering | 2011 |
Dutch guideline for the management of hypertensive crisis -- 2010 revision.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Emergency Treatment; Humans; Hypertension; Hypertensive Retinopathy; Internal Medicine; Labetalol; Netherlands; Nicardipine; Nifedipine; Nitroprusside; Practice Guidelines as Topic | 2011 |
[Comparison of the rate of maternal complications of nifedipine and nicardipine in cases of preterm labor: historical study on two consecutive periods].
Topics: Adult; Calcium Channel Blockers; Female; France; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature; Pregnancy; Retrospective Studies; Tocolytic Agents | 2012 |
Nifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses.
Topics: Animals; Axotomy; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Death; Cholinergic Neurons; Dopaminergic Neurons; Isradipine; Neuroimmunomodulation; Neuroprotective Agents; Nicardipine; Nifedipine; Nimodipine; Rats, Sprague-Dawley; Substantia Nigra; Tissue Culture Techniques; Ventral Tegmental Area; Verapamil | 2014 |
An Assessment of the Oral Bioavailability of Three Ca-Channel Blockers Using a Cassette-Microdose Study: A New Strategy for Streamlining Oral Drug Development.
Topics: Administration, Intravenous; Administration, Oral; Adult; Biological Availability; Calcium Channel Blockers; Chromatography, Liquid; Diltiazem; Humans; Male; Mass Spectrometry; Nicardipine; Nifedipine; Young Adult | 2015 |
Comparison of anti-anginal effect of cilnidipine with those of nicardipine and nifedipine in the vasopressin-induced angina model of rats.
Topics: Angina Pectoris; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Coronary Vasospasm; Coronary Vessels; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Male; Nicardipine; Nifedipine; Rats; Time Factors; Vasoconstriction; Vasodilator Agents; Vasopressins | 2016 |
Evaluation of four calcium channel blockers as fluconazole resistance inhibitors in Candida glabrata.
Topics: Calcium Channel Blockers; Candida glabrata; Diltiazem; Dose-Response Relationship, Drug; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Microbial Sensitivity Tests; Microbial Viability; Nicardipine; Nifedipine; Verapamil | 2018 |
Polymer degradation induced drug precipitation in PLGA implants - Why less is sometimes more.
Topics: Biodegradable Plastics; Calcium Channel Blockers; Calorimetry, Differential Scanning; Drug Carriers; Drug Compounding; Drug Implants; Drug Liberation; Humans; Nicardipine; Nifedipine; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; X-Ray Diffraction | 2019 |