nifedipine has been researched along with niacinamide in 66 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (40.91) | 18.7374 |
| 1990's | 31 (46.97) | 18.2507 |
| 2000's | 3 (4.55) | 29.6817 |
| 2010's | 4 (6.06) | 24.3611 |
| 2020's | 1 (1.52) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Murao, S; Uchida, Y; Yoshimoto, N | 2 |
| Berdeaux, A; Drieu la Rochelle, C; Giudicelli, JF; Richard, V | 1 |
| Auchampach, JA; Gross, GJ; Maruyama, M; Pieper, GM; Warltier, DC | 1 |
| Diderholm, E; Frithz, G; Gudbrandsson, T; Hedbäck, B; Höglund, C; Moelstad, P; Perk, J; Sverrisson, JT; Ulvenstam, G | 1 |
| Bauters, C; Bertrand, ME; Lablanche, JM; Leroy, F | 1 |
| Fukata, Y; Fukushima, H; Jinno, Y; Kaneta, S; Nishikori, K; Ogawa, N | 1 |
| Satoh, E; Taira, N; Yanagisawa, T | 1 |
| Akiyama, H; Kobayashi, I; Kobayashi, S; Mori, M; Shiono, S; Yamada, M; Yamaguchi, M | 1 |
| Kato, A; Nakamura, F; Sugimoto, T; Sumino, S; Tomaru, T; Uchida, Y | 1 |
| Gross, GJ; Hardman, HF; Warltier, DC | 1 |
| Imai, S; Katano, Y; Nabata, H; Nakagawa, Y; Nakazawa, M; Takeda, K; Tsukada, T; Ushijima, T | 1 |
| Hakuta, T; Kobayashi, K | 1 |
| Sugimoto, T; Uchida, Y | 1 |
| Ishii, K; Sato, Y; Taira, N | 1 |
| Hashimoto, H; Taira, N; Yanagisawa, T | 2 |
| Fujimoto, M; Kitao, T; Kohara, H; Kumahara, Y; Morimoto, K; Ogihara, T; Ohde, H; Tai, H; Terada, K | 1 |
| Li, DM; Wang, XW; Zhang, KJ; Zhou, CM | 1 |
| Hester, RK | 1 |
| Flores, F; Hester, RK; Satake, N; Shibata, S; Ueda, S | 1 |
| Brooks, HL; Gross, GJ; Warltier, DC; Wynsen, JC | 1 |
| Imai, S; Matsui, K; Ogawa, Y | 1 |
| Hader, S; Leitold, M | 1 |
| Araki, H; Hayata, N; Matsuguchi, T; Nakamura, M | 1 |
| Clapham, JC; Wilson, C | 1 |
| Hashimoto, T; Kaguchi, Y; Kimura, M; Kuriyama, S; Miyahara, T; Nakamura, K; Tamai, K; Tamura, H | 1 |
| Uchida, Y | 1 |
| Ishii, K; Satoh, K; Taira, N; Yanagisawa, T | 1 |
| Imai, S; Nabata, H; Nakazawa, M; Sakai, K; Ushijima, T | 1 |
| Gross, GJ; Hardman, HF; Lamping, KA; Warltier, DC | 1 |
| Hirakawa, S; Ito, H | 1 |
| Kerfoot, F; Satake, N; Shibata, S; Suh, TK; Takagi, T | 1 |
| Imamura, Y; Muramatsu, K; Nakamura, M; Narishige, T; Takahashi, T; Takeshita, A; Tomoike, H | 1 |
| Fukata, Y; Fukushima, H; Harada, K; Jinno, Y; Kaneta, S; Ogawa, N | 1 |
| Fukushima, H; Jinno, Y; Kaneta, S; Miwa, A; Ogawa, N | 1 |
| Masuda, Y; Tanaka, S; Yamashita, T | 1 |
| Ando, S; Endo, T; Imaizumi, T; Kubo, T; Shiramoto, M; Tagawa, T; Takeshita, A; Tokunaga, S | 1 |
| Miyata, N; Otomo, S; Takahashi, K; Tsuchida, K; Yamaura, H | 1 |
| Hirakawa, Y; Kanaide, H; Kuga, T; Takeshita, A | 1 |
| Fukata, Y; Fukushima, H; Harada, K; Kaneta, S; Miwa, A; Ogawa, N | 1 |
| Ballardie, FW; Chalmers, RJ; Daley-Yates, PT; Edwards, BD; Lawson, RS; Maiza, A; O'Driscoll, JB; Testa, HJ | 1 |
| Miyata, N; Otomo, S; Takahashi, K; Tanaka, M; Tsuchida, K; Yamaura, H | 1 |
| Egashira, K; Fukai, T; Hata, H; Kasuya, H; Kuga, T; Takahashi, T; Takeshita, A | 1 |
| Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K | 1 |
| Araki, H; Higuchi, S; Masumiya, H; Noguchi, K; Sasaki, T; Shigenobu, K; Takahashi, K; Tanaka, H | 1 |
| Angus, JA; Fujiwara, T | 1 |
| Murayama, S; Nakano, T; Yamakado, T | 1 |
| Takahashi, K; Takahashi, T; Tanikawa, S | 1 |
| Houchi, H; Nakaya, Y; Oka, M; Shono, M | 1 |
| Sunada, H; Suzuki, H | 3 |
| Araki, H; Higuchi, S; Noguchi, K; Takahashi, K | 1 |
| Aisaka, K; Hirata, Y; Mabuchi, Y; Miyai, H | 1 |
| Higuchi, S; Nakasone, C; Noguchi, K; Shigenobu, K; Shijuku, T; Takahashi, K; Tanaka, H; Tanaka, Y | 1 |
| Ota, T; Takahashi, K; Takahashi, T; Tanikawa, S | 1 |
| Higuchi, S; Noguchi, K; Takahashi, K | 1 |
| Hashii, M; Higashida, H; Minabe, Y | 1 |
| Connor, J; Livesey, SA; Martowicz, ML; Wagner, CT | 1 |
| Kerry, Z; Ozer, A; Reel, B; Sevin, G; Yasa, M; Yetik Anacak, G | 1 |
| Bisenieks, E; Duburs, G; Gall Troselj, K; Krauze, A; Poikans, J; Velena, A; Zarkovic, N | 1 |
| Bao, J; Mei, X; Wang, JR; Yan, Z; Yu, Q | 1 |
| He, M; Liu, L; Sun, X; Wang, P; Yang, X; Zhang, Y; Zhao, H; Zhao, J; Zhu, Z | 1 |
1 review(s) available for nifedipine and niacinamide
| Article | Year |
|---|---|
1,4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues-Model Compounds Targeting Oxidative Stress.
Topics: Amlodipine; Animals; Antioxidants; Azetidinecarboxylic Acid; Calcium Channel Blockers; Cattle; Dihydropyridines; Epithelial Cells; Humans; Hydrogen; Lipoproteins, LDL; Mice; Microsomes; Mitochondria; Niacinamide; Nifedipine; Nitrobenzenes; Oxidants; Oxidative Stress; Piperazines | 2016 |
3 trial(s) available for nifedipine and niacinamide
| Article | Year |
|---|---|
Antianginal and anti-ischemic efficacy of nicorandil compared with nifedipine in patients with angina pectoris and coronary heart disease: a double-blind, randomized, multicenter study.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Double-Blind Method; Electrocardiography; Exercise; Female; Heart Rate; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nifedipine; Potassium Channels; Tablets | 1992 |
Prevention of coronary spasm by nicorandil: comparison with nifedipine.
Topics: Administration, Oral; Adult; Coronary Vasospasm; Double-Blind Method; Ergonovine; Humans; Middle Aged; Niacinamide; Nicorandil; Nifedipine; Vasodilator Agents | 1992 |
Effects of nicorandil, an antianginal potassium channel opener, on left ventricular systolic and diastolic function in patients with chronic coronary artery disease.
Topics: Adult; Aged; Chronic Disease; Coronary Disease; Diastole; Female; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium Channels; Systole; Vasodilator Agents; Ventricular Function, Left; Ventricular Pressure | 1997 |
62 other study(ies) available for nifedipine and niacinamide
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effects of anti-anginal agents on cyclical reductions of coronary blood flow.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Blood Pressure; Coronary Circulation; Diltiazem; Dipyridamole; Dogs; Electrocardiography; Injections, Intravenous; Niacinamide; Nicotinic Acids; Nifedipine; Nitrates; Nitroglycerin; Papaverine; Periodicity; Phentolamine; Propranolol; Vasodilator Agents; Verapamil | 1978 |
Effect of 2-nicotinamidethyl nitrate (SG 75) on coronary circulation.
Topics: Animals; Constriction, Pathologic; Coronary Circulation; Coronary Vessels; Diltiazem; Dogs; Heart Rate; Isosorbide Dinitrate; Ligation; Niacinamide; Nifedipine; Nitrates; Nitroglycerin; Papaverine; Vasodilator Agents; Verapamil | 1978 |
Differential effects of nitrovasodilators, K(+)-channel openers, and nicorandil on large and small coronary arteries in conscious dogs.
Topics: Animals; Benzopyrans; Coronary Vessels; Cromakalim; Dogs; Dose-Response Relationship, Drug; Injections, Intravenous; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilation; Vasodilator Agents | 1992 |
Cardioprotective effects of nicorandil.
Topics: Animals; Benzopyrans; Coronary Circulation; Dihydropyridines; Dogs; Female; Heart; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Neutrophils; Niacinamide; Nicorandil; Nifedipine; Potassium Channels; Rats; Rats, Sprague-Dawley; Reperfusion; Superoxides | 1992 |
Comparison of KRN2391 with nicorandil and nifedipine on canine coronary blood flow: antagonism by glibenclamide.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Heart Rate; Male; Niacinamide; Nicorandil; Nifedipine; Potassium Channels; Pyridines; Vascular Resistance | 1992 |
Specific antagonism by glibenclamide of negative inotropic effects of potassium channel openers in canine atrial muscle.
Topics: Animals; Benzopyrans; Carbachol; Cromakalim; Dogs; Female; Glyburide; Guanidines; Heart Atria; Male; Myocardial Contraction; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1990 |
Thyrotropin-releasing hormone stimulation of thyrotropin secretion is suppressed by calcium ion antagonists that block transmembrane influx and intracellular mobilization of calcium ion in human subjects.
Topics: Adult; Calcium; Calcium Channel Blockers; Humans; Ion Channels; Male; Niacinamide; Nicorandil; Nifedipine; Thyrotropin; Thyrotropin-Releasing Hormone | 1986 |
Phasic contractions of canine and human coronary arteries induced by potassium channel blockers.
Topics: 4-Aminopyridine; Adult; Aged; Amifampridine; Aminopyridines; Angina Pectoris, Variant; Animals; Arteries; Coronary Vasospasm; Coronary Vessels; Dogs; Female; Humans; Ion Channels; Macaca mulatta; Male; Middle Aged; Models, Biological; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Swine; Tetraethylammonium Compounds; Vasoconstriction | 1986 |
Comparative effects of nicorandil, a nicotinamide nitrate derivative, and nifedipine on myocardial reperfusion injury in dogs.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Female; Male; Myocardial Contraction; Myocardial Infarction; Niacinamide; Nicorandil; Nifedipine | 1987 |
Effects of nicorandil on the conductive coronary artery of the dog.
Topics: Animals; Coronary Vessels; Dogs; Female; In Vitro Techniques; Lanthanum; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Perfusion; Potassium; Vasoconstriction; Vasodilator Agents | 1987 |
Effects of nicorandil on coronary hemodynamics in ischemic heart disease: comparison with nitroglycerin, nifedipine, and propranolol.
Topics: Adult; Aged; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Lactates; Lactic Acid; Middle Aged; Myocardium; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Norepinephrine; Oxygen Consumption; Propranolol; Vasodilator Agents | 1987 |
The effects of nicorandil on phasic contractions of isolated canine coronary artery.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calmodulin; Coronary Vessels; Dogs; Ergonovine; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Vasodilator Agents | 1987 |
Differential antagonism by Bay K 8644 of vasodilator effects of nifedipine, diltiazem, nicorandil and nitroglycerin in dog femoral circulation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Femoral Artery; Femur; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Regional Blood Flow; Vasodilator Agents | 1988 |
Interaction of potassium channel openers and blockers in canine atrial muscle.
Topics: Animals; Barium; Barium Compounds; Chlorides; Dogs; Female; Guanidines; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Quaternary Ammonium Compounds; Tetraethylammonium Compounds | 1989 |
Effects of the kallikrein-kinin system on phasic coronary vasospasm in dogs.
Topics: Animals; Bradykinin; Coronary Vasospasm; Coronary Vessels; Diltiazem; Dogs; Female; In Vitro Techniques; Kallikreins; Male; Niacinamide; Nicorandil; Nifedipine; Vasoconstriction; Vasodilator Agents | 1989 |
[Effects of 2[p-(dimethylamino)styryl]pyridine methiodide on action potentials of sinoatrial node cells of rabbits].
Topics: Action Potentials; Animals; Calcium Channel Blockers; Female; Humans; Isoproterenol; Male; Niacinamide; Nifedipine; Pyridinium Compounds; Rabbits; Sinoatrial Node | 1989 |
Effects of 2-nicotinamidoethyl nitrate on agonist-sensitive Ca++ release and Ca++ entry in rabbit aorta.
Topics: Animals; Aorta; Biological Transport; Calcium; Female; Gallopamil; Ion Channels; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Norepinephrine; Potassium Chloride; Rabbits | 1985 |
The negative inotropic effect of nicorandil is independent of cyclic GMP changes: a comparison with pinacidil and cromakalim in canine atrial muscle.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzopyrans; Cromakalim; Cyclic AMP; Cyclic GMP; Dogs; Female; Guanidines; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Tetraethylammonium Compounds; Vasodilator Agents | 1988 |
Effect of nicorandil, N-(2-hydroxyethyl)nicotinamide nitrate, a new anti-anginal agent, on contractile responses to alpha-1- and alpha-2-adrenoceptor agonists in isolated rabbit aorta.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Azepines; Clonidine; Male; Methoxamine; Niacinamide; Nicorandil; Nifedipine; Rabbits; Vasodilation | 1986 |
Differential effects of nifedipine, nicorandil and nitroglycerin on the pressor responses elicited by selective alpha-1 and alpha-adrenoceptor agonists in conscious dogs.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Dogs; Female; Hemodynamics; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Phenylephrine; Vasodilator Agents | 1987 |
Relaxant effects of pinacidil, nicorandil, hydralazine and nifedipine as studied in the porcine coronary artery and guinea-pig taenia coli.
Topics: Animals; Caffeine; Colon; Coronary Vessels; Female; Guanidines; Guinea Pigs; Hydralazine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium; Swine; Vasodilator Agents | 1986 |
[Influence of antianginal drugs on Lypressin induced T-wave enhancement in the electrocardiogram of the rat].
Topics: Administration, Oral; Angina Pectoris; Animals; Coronary Vasospasm; Electrocardiography; Hypoxia; Isosorbide Dinitrate; Lypressin; Male; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Effects of nicorandil on rest and effort angina unresponsive to combination therapy with a calcium antagonist and oral nitrate.
Topics: Aged; Aged, 80 and over; Angina Pectoris; Diltiazem; Drug Resistance; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Niacinamide; Nicorandil; Nifedipine; Physical Exertion; Prospective Studies; Rest; Vasodilator Agents | 1987 |
Anti-spasmogenic and spasmolytic effects of BRL 34915: a comparison with nifedipine and nicorandil.
Topics: Animals; Benzopyrans; Cromakalim; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Norepinephrine; Parasympatholytics; Potassium Chloride; Pyrroles; Rabbits | 1987 |
The effects of vasoactive agents on the proliferation of vascular smooth muscle cells grown in vitro.
Topics: Amiloride; Animals; Captopril; Cell Division; Cells, Cultured; Chlorpromazine; In Vitro Techniques; Labetalol; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Norepinephrine; Propranolol; Quinazolines; Rats; Sulfonamides | 1988 |
Decreasing potassium conductance--a possible mechanism of phasic coronary vasospasm.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Coronary Vasospasm; Coronary Vessels; Dogs; Ergonovine; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Macaca mulatta; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardium; Niacinamide; Nicorandil; Nifedipine; Potassium; Swine; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
Abolition of spontaneous rhythmic contractions of isolated monkey coronary arteries by diltiazem, nifedipine, verapamil and nicorandil but not by nitroglycerin.
Topics: Animals; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Erythrocebus patas; Female; In Vitro Techniques; Macaca mulatta; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Verapamil | 1985 |
Mechanism of relaxant effects of nicorandil on the dog coronary artery.
Topics: Animals; Caffeine; Calcium; Coronary Vessels; Dogs; Female; Lanthanum; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium; Vasoconstriction; Vasodilation; Vasodilator Agents | 1983 |
Effects of nicorandil, a new antianginal agent, and nifedipine on collateral blood flow in a chronic coronary occlusion model.
Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Female; Hemodynamics; Male; Niacinamide; Nicorandil; Nifedipine; Vasodilator Agents | 1984 |
Effects of vasodilators on the systemic capacitance vessels, a study with the measurement of the mean circulatory pressure in dogs.
Topics: Animals; Blood Pressure; Blood Vessels; Blood Volume; Cardiac Output; Diltiazem; Dogs; Heart Rate; Isosorbide Dinitrate; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Prazosin; Sydnones; Trapidil; Vascular Resistance; Vasodilator Agents; Venous Pressure; Verapamil | 1984 |
Relaxing effect of nicorandil (N-2-(hydroxyethyl)-nicotinamide nitrate), a new anti-angina agent, on the isolated vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Basilar Artery; Calcium; Cats; Coronary Vessels; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Norepinephrine; Potassium Chloride; Rabbits; Vasodilator Agents | 1984 |
Effects of a new calcium antagonist, CD-832, on coronary and systemic hemodynamics in conscious dogs.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Niacinamide; Nifedipine | 1994 |
Hemodynamic profile of KRN2391, a novel vasodilator, in anesthetized dogs.
Topics: Anesthesia; Animals; Blood Pressure; Cerebrovascular Circulation; Coronary Circulation; Dogs; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Injections, Intra-Arterial; Injections, Intravenous; Male; Niacinamide; Nicorandil; Nifedipine; Pyridines; Regional Blood Flow; Renal Circulation; Splanchnic Circulation; Vascular Resistance; Vasodilator Agents | 1993 |
Effect of KRN2391 on venous return: comparison with other vasodilators.
Topics: Animals; Benzopyrans; Cromakalim; Dogs; Female; Glyburide; Hemodynamics; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium Channels; Pyridines; Pyrroles; Vasodilator Agents; Veins | 1993 |
Potassium channel openers relax A23187-induced nifedipine-resistant contraction of rat aorta.
Topics: Animals; Aorta; Benzopyrans; Calcimycin; Cromakalim; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Oxadiazoles; Piperidines; Pyrroles; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents | 1994 |
Effects of a novel dihydropyridine calcium antagonist on venous capacitance in Wistar-Kyoto rats.
Topics: Animals; Blood Pressure; Blood Volume; Calcium Channel Blockers; Drug Interactions; Ethanol; Hemodynamics; Hexamethonium Compounds; Male; Niacinamide; Nifedipine; Nitroglycerin; Phenylephrine; Rats; Rats, Inbred WKY; Sympathectomy, Chemical; Vascular Resistance | 1994 |
Effects of CD-832, a dihydropyridine derivative with a nitrate ester moiety on rabbit femoral artery and vein.
Topics: Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Femoral Artery; Femoral Vein; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nifedipine; Norepinephrine; Potassium Chloride; Rabbits | 1994 |
Actions of a new Ca2+ channel antagonist, CD832, on two types of Ca2+ channels in smooth muscle.
Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Male; Muscle, Smooth, Vascular; Niacinamide; Nifedipine; Rats; Rats, Wistar | 1994 |
Effect of KRN2391, a novel vasodilator, on various experimental anginal models in rats.
Topics: Angina Pectoris; Animals; Disease Models, Animal; Electrocardiography; Injections, Intravenous; Isoproterenol; Male; Methacholine Chloride; Niacinamide; Nicorandil; Nifedipine; Pyridines; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
Altered clearance of N-1 methylnicotinamide associated with the use of low doses of cyclosporine.
Topics: Analysis of Variance; Cyclosporine; Drug Therapy, Combination; Humans; Kidney Function Tests; Kidney Tubules, Proximal; Metabolic Clearance Rate; Niacinamide; Nifedipine; Renal Circulation | 1994 |
CD-832, a new dihydropyridine derivative with both nitrate-like and Ca2+ channel antagonist vasodilator activities.
Topics: Animals; Aorta, Thoracic; Brain Chemistry; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nifedipine; Nitrates; Rabbits; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
Effects of a new calcium antagonist, CD-832, on experimental coronary artery spasm in miniature pigs.
Topics: Animals; Calcium Channel Blockers; Coronary Vasospasm; Disease Models, Animal; Histamine; Infusions, Intravenous; Ketanserin; Niacinamide; Nifedipine; Radiography; Serotonin; Swine; Swine, Miniature | 1993 |
Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis.
Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Female; Heart Rate; Isoproterenol; Male; Myocardial Ischemia; Niacinamide; Nifedipine | 1996 |
Relative selectivity for negative chronotropic and inotropic effects of a novel dihydropyridine derivative CD-832.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Guinea Pigs; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Niacinamide; Nifedipine; Osmolar Concentration; Papillary Muscles; Patch-Clamp Techniques; Verapamil | 1996 |
Analysis of relaxation and repolarization mechanisms of nicorandil in rat mesenteric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Electrophysiology; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Protective effects of CD-832 on organ damage in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Cerebrovascular Disorders; Diltiazem; Heart Rate; Hypertension; Kidney; Male; Myocardium; Niacinamide; Nifedipine; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1997 |
Effects of nitroprusside and nicorandil on catecholamine secretion and calcium mobilization in cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Glyburide; Niacinamide; Nicorandil; Nifedipine; Nitroprusside; Vasodilator Agents | 1997 |
Comparison of nicotinamide, ethylurea and polyethylene glycol as carriers for nifedipine solid dispersion systems.
Topics: Calcium Channel Blockers; Calorimetry, Differential Scanning; Drug Carriers; Lactose; Methylcellulose; Niacinamide; Nifedipine; Oxazines; Polyethylene Glycols; Solubility; Urea; X-Ray Diffraction | 1997 |
Vasodilation profile of CD-832, a novel dihydropyridine derivative in rabbit aorta.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Calcium Channel Blockers; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Niacinamide; Nicorandil; Nifedipine; Nitrendipine; Nitroglycerin; Norepinephrine; Potassium Chloride; Rabbits; Vasodilation; Vasodilator Agents | 1997 |
Mechanistic studies on hydrotropic solubilization of nifedipine in nicotinamide solution.
Topics: Drug Stability; Niacinamide; Nifedipine; Nikethamide; Nipecotic Acids; Solubility; Temperature; Thermodynamics; Urea | 1998 |
Effect of JTV-506, a novel vasodilator, on experimental angina model in rats.
Topics: Administration, Oral; Angina Pectoris; Animals; Arginine Vasopressin; Blood Pressure; Chromans; Cromakalim; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Injections, Intravenous; Male; Methacholine Chloride; Molecular Structure; Niacinamide; Nicorandil; Nifedipine; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Possible involvement of nitric oxide-cGMP pathway in the negative chronotropic effect of CD-832, a novel dihydropyridine derivative.
Topics: Animals; Calcium Channel Blockers; Cyclic GMP; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Molsidomine; Niacinamide; Nifedipine; Nitric Oxide | 1998 |
Influence of water-soluble polymers on the dissolution of nifedipine solid dispersions with combined carriers.
Topics: Calcium Channel Blockers; Drug Carriers; Drug Interactions; Niacinamide; Nifedipine; Polymers; Solubility; Temperature | 1998 |
Effects of CD-832, a new calcium antagonist, on intracranial pressure in anesthetized dogs.
Topics: Anesthesia; Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Intracranial Pressure; Male; Niacinamide; Nifedipine; Regional Blood Flow | 1998 |
In-vitro negative chronotropic and inotropic effects of a novel dihydropyridine derivative, CD-832, in the guinea-pig: comparison with calcium-channel antagonists.
Topics: Animals; Calcium Channel Blockers; Depression, Chemical; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Niacinamide; Nifedipine; Papillary Muscles; Structure-Activity Relationship | 1998 |
cADP-ribose potentiates cytosolic Ca2+ elevation and Ca2+ entry via L-type voltage-activated Ca2+ channels in NG108-15 neuronal cells.
Topics: Adenosine Diphosphate Ribose; Biological Transport; Calcium; Calcium Channels, L-Type; Cells, Cultured; Cyclic ADP-Ribose; Cytosol; Ion Channel Gating; Manganese; Membrane Potentials; Models, Biological; NAD; Neurons; Niacinamide; Nifedipine; Patch-Clamp Techniques; Ryanodine; Ryanodine Receptor Calcium Release Channel; Tacrolimus | 2000 |
Biochemical stabilization enhances red blood cell recovery and stability following cryopreservation.
Topics: Blood Preservation; Cryopreservation; Cryoprotective Agents; Dextrans; Erythrocyte Membrane; Erythrocytes; Flurbiprofen; Glycerol; Humans; Hydroxyethyl Starch Derivatives; In Vitro Techniques; Niacinamide; Nifedipine; Osmotic Fragility; Thermodynamics | 2002 |
Diverse effects of calcium channel blockers in the collar model.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Calcium Channel Blockers; Carotid Artery, Common; Endothelium, Vascular; Female; Histamine Agents; Male; Models, Animal; Models, Cardiovascular; Niacinamide; Nifedipine; Phenylephrine; Potassium Chloride; Rabbits; Serotonin; Serotonin Agents; Tunica Intima; Vasodilation; Vasodilator Agents | 2005 |
Taming photo-induced oxidation degradation of dihydropyridine drugs through cocrystallization.
Topics: Calcium Channel Blockers; Crystallization; Dihydropyridines; Molecular Conformation; Niacinamide; Nifedipine; Oxidation-Reduction; Photochemical Processes; Thermodynamics | 2017 |
The fingerprints of nifedipine/isonicotinamide cocrystal polymorph studied by terahertz time-domain spectroscopy.
Topics: Niacinamide; Nifedipine; Pharmaceutical Preparations; Terahertz Spectroscopy; Vibration | 2022 |