nifedipine has been researched along with naloxone in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (7.14) | 18.7374 |
| 1990's | 20 (47.62) | 18.2507 |
| 2000's | 11 (26.19) | 29.6817 |
| 2010's | 7 (16.67) | 24.3611 |
| 2020's | 1 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Done, C; Sharp, T; Silverstone, PH | 1 |
| Espinoza, M; Flores, R; Ortiz, S; Schnur, P; Vallejos, S; Wainwright, M | 1 |
| Abraham, J; Chandy, M; Cherian, L; Kuruvilla, A | 1 |
| Schnur, P | 1 |
| Grice, JE; Hockings, GI; Jackson, RV; Walters, MM | 1 |
| Koelbel, CB; Leduc, L; Mayer, EA; Snape, WJ; Vandeventer, G | 1 |
| Morrone, LA; Pimpinella, G; Romanelli, L; Valeri, P | 1 |
| Martinelli, B; Morrone, LA; Severini, C; Valeri, P | 1 |
| Adamson, P; Brammer, MJ; Campbell, IC; Xiang, JZ | 1 |
| Antkiewicz-Michaluk, L; Michaluk, J; Romańska, I; Vetulani, J | 1 |
| Kavaliers, M | 1 |
| Kavaliers, M; Ossenkopp, KP | 1 |
| Adamson, P; Brammer, MJ; Campbell, IC; Mantzourides, T; Xiang, JZ | 1 |
| Crosbie, GV; Grice, JE; Hockings, GI; Jackson, RV; Torpy, DJ; Walters, MM | 1 |
| Jin, RL; Wu, YY; Xu, Q | 1 |
| Amico, MC; Morrone, LA; Romanelli, L; Valeri, P | 1 |
| Crosbie, GV; Grice, JE; Hockings, GI; Jackson, RV; Walters, MM | 1 |
| Bridges, MT; Grover, TE; Introna, RP; Pruett, JK; Yodlowski, EH | 1 |
| Civelli, O; Kemp, JA; Knoflach, F; Reinscheid, RK | 1 |
| Duncan, MJ; Elde, RP; Gurwell, JA; Hauser, KF; Maderspach, K; Stiene-Martin, A | 1 |
| Moises, HC; Rusin, KI | 1 |
| Carabelli, V; Carbone, E; Carra, I | 1 |
| He, J; Xiao, Y; Zhang, L | 1 |
| Aoki, Y; Asai, M; Iwasaki, Y; Mutsuga, N; Nomura, A; Oiso, Y; Saito, H; Yamamori, E; Yoshida, M | 1 |
| Li, J; Liu, Y; Lu, XQ; Piletz, JE; Qin, BY; Su, RB; Wu, N; Xu, B; Zheng, JQ | 1 |
| Ahmadiani, A; Esmaeili-Mahani, S; Fathi, Y; Hosseinpanah, F; Motamedi, F | 1 |
| Abignano, G; Lettieri, G; Mennillo, GA | 1 |
2 review(s) available for nifedipine and naloxone
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for nifedipine and naloxone
| Article | Year |
|---|---|
A synergistic adrenocorticotropin response to naloxone and vasopressin in normal humans: evidence that naloxone stimulates endogenous corticotropin-releasing hormone.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Arginine Vasopressin; Calcium; Corticotropin-Releasing Hormone; Drug Synergism; Female; Humans; Male; Middle Aged; Naloxone; Nifedipine; Reference Values; Single-Blind Method; Stimulation, Chemical | 1995 |
Altered hypothalamic-pituitary-adrenal axis responsiveness in myotonic dystrophy: in vivo evidence for abnormal dihydropyridine-insensitive calcium transport.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Biological Transport; Calcium; Child; Dihydropyridines; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Myotonic Dystrophy; Naloxone; Nifedipine; Pituitary-Adrenal System; Reference Values | 1993 |
38 other study(ies) available for nifedipine and naloxone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Clonidine but not nifedipine prevents the release of noradrenaline during naloxone-precipitated opiate withdrawal: an in vivo microdialysis study in the rat.
Topics: Animals; Behavior, Animal; Clonidine; Male; Microdialysis; Morphine Dependence; Naloxone; Nifedipine; Norepinephrine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Weight Loss | 1992 |
Blocking naloxone-precipitated withdrawal in rats and hamsters.
Topics: Animals; Behavior, Animal; Clonidine; Cricetinae; Drug Implants; Mesocricetus; Morphine Dependence; Naloxone; Nifedipine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Verapamil; Yawning | 1992 |
Evaluation of drug effects on spinal cord injury--an experimental study in monkeys.
Topics: Animals; Dimethyl Sulfoxide; Dipyridamole; Drug Evaluation, Preclinical; Female; Macaca radiata; Male; Naloxone; Nifedipine; Spinal Cord Injuries | 1992 |
Morphine withdrawal in the hamster.
Topics: Animals; Clonidine; Cricetinae; Morphine; Naloxone; Nifedipine; Stereotyped Behavior; Substance Withdrawal Syndrome; Verapamil | 1992 |
L-type calcium channels and CRH-mediated ACTH and cortisol release in humans.
Topics: Adrenocorticotropic Hormone; Adult; Calcium Channels; Corticotropin-Releasing Hormone; Female; Humans; Hydrocortisone; Male; Middle Aged; Naloxone; Nifedipine; Single-Blind Method; Time Factors | 1991 |
Neurokinin inhibition of cholinergic myenteric neurons in canine antrum.
Topics: Acetylcholine; Animals; Atropine; Dinoprostone; Dogs; Electric Stimulation; Enkephalin, Methionine; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth; Myenteric Plexus; Naloxone; Neurokinin A; Neurons; Nifedipine; Phentolamine; Propranolol; Pyloric Antrum; Substance P; Tetrodotoxin; Vasoactive Intestinal Peptide | 1990 |
Some pharmacological characteristics of the guinea pig ileum opioid system activated by cholecystokinin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Cholecystokinin; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Receptors, Opioid; Yohimbine | 1990 |
Reproducible withdrawal contractions of isolated guinea-pig ileum after brief morphine exposure: effects of clonidine and nifedipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Substance Withdrawal Syndrome; Yohimbine | 1990 |
The kappa-opiate agonist U50488H decreases the entry of 45Ca into rat cortical synaptosomes by inhibiting N- but not L-type calcium channels.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cerebral Cortex; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Naloxone; Nerve Endings; Neuromuscular Depolarizing Agents; Nifedipine; omega-Conotoxin GVIA; Peptides, Cyclic; Potassium; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Synaptosomes | 1990 |
Cortical dihydropyridine binding sites and a behavioral syndrome in morphine-abstinent rats.
Topics: Animals; Behavior, Animal; Brain Chemistry; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Dihydropyridines; Hippocampus; Male; Morphine Dependence; Naloxone; Nifedipine; Nitrendipine; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Substance Withdrawal Syndrome | 1990 |
Stimulatory influences of calcium channel antagonists on stress-induced opioid analgesia and locomotor activity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Diltiazem; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Immobilization; Mice; Mice, Inbred C57BL; Motor Activity; Naloxone; Nifedipine; Pain; Reaction Time; Stress, Physiological; Verapamil | 1987 |
Magnetic fields inhibit opioid-mediated 'analgesic' behaviours of the terrestrial snail, Cepaea nemoralis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Calcium; Diltiazem; Ion Channels; Magnetics; Morphine; Naloxone; Nifedipine; Nociceptors; Pyrrolidines; Snails; Temperature; Verapamil | 1988 |
Presynaptic alpha 2-adrenoceptor and kappa-opiate receptor occupancy promotes closure of neuronal (N-type) calcium channels.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzofurans; Calcium; Calcium Channels; Clonidine; Dioxanes; Fura-2; Idazoxan; In Vitro Techniques; Male; Mollusk Venoms; Naloxone; Neurons; Nifedipine; omega-Conotoxin GVIA; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, kappa; Synapses; Synaptosomes | 1989 |
Opioid, calcium, and adrenergic receptor involvement in protopine analgesia.
Topics: Alkaloids; Analgesics; Animals; Benzophenanthridines; Berberine Alkaloids; Drugs, Chinese Herbal; Female; Methotrexate; Mice; Mice, Inbred ICR; Naloxone; Nifedipine; Pain Threshold; Phentolamine; Reserpine | 1993 |
Withdrawal contractures of guinea-pig isolated ileum after acute activation of kappa-opioid receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Nifedipine; Pyrrolidines; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 1993 |
Direct effects of fentanyl on canine coronary artery rings.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Intravenous; Animals; Arteries; Calcium Channel Blockers; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Fentanyl; In Vitro Techniques; Indomethacin; Male; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nifedipine; Prazosin; Propranolol; Vasoconstriction | 1995 |
Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons.
Topics: Animals; Barium; Biological Transport; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Ion Channel Gating; Naloxone; Narcotic Antagonists; Nifedipine; Nociceptin; omega-Agatoxin IVA; omega-Conotoxin GVIA; Opioid Peptides; Patch-Clamp Techniques; Peptides; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spider Venoms | 1996 |
kappa-opioid receptor expression defines a phenotypically distinct subpopulation of astroglia: relationship to Ca2+ mobilization, development, and the antiproliferative effect of opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Astrocytes; Benzeneacetamides; Bromodeoxyuridine; Calcium; Calcium Channel Blockers; Cell Count; Cell Division; Cells, Cultured; DNA; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Immunohistochemistry; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Nifedipine; Phenotype; Pyrrolidines; Receptors, Opioid, kappa; Thapsigargin; Time Factors | 1996 |
Mu-opioid and GABA(B) receptors modulate different types of Ca2+ currents in rat nodose ganglion neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics, Opioid; Animals; Baclofen; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Agonists; GABA Antagonists; Naloxone; Narcotic Antagonists; Nerve Tissue Proteins; Neurons; Nifedipine; Nodose Ganglion; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Spider Venoms | 1998 |
Localized secretion of ATP and opioids revealed through single Ca2+ channel modulation in bovine chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Analgesics; Analgesics, Opioid; Animals; Antineoplastic Agents; Autocrine Communication; Barium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Cattle; Chromaffin Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Exocytosis; Ion Channel Gating; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Opioid Peptides; Patch-Clamp Techniques; Peptides; Receptors, Opioid; Receptors, Purinergic; Spider Venoms; Suramin; Virulence Factors, Bordetella | 1998 |
Cocaine induces apoptosis in human coronary artery endothelial cells.
Topics: Apoptosis; Caspase Inhibitors; Cells, Cultured; Cocaine; Coronary Vessels; Cyclosporine; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Humans; Naloxone; Narcotic Antagonists; Nifedipine; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Effects of loperamide and other opioid-related substances on the transcriptional regulation of the rat pro-opiomelanocortin gene in AtT20 cells.
Topics: Animals; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Gene Expression; Loperamide; Mice; Naloxone; Nifedipine; Nociceptin; Oligopeptides; Opioid Peptides; Pro-Opiomelanocortin; Receptors, Opioid, mu; Sulfonamides; Time Factors | 2001 |
IRAS, a candidate for I1-imidazoline receptor, mediates inhibitory effect of agmatine on cellular morphine dependence.
Topics: Agmatine; Animals; CHO Cells; Cricetinae; Cyclic AMP; Dizocilpine Maleate; Imidazoles; Imidazoline Receptors; Intracellular Signaling Peptides and Proteins; Morphine; Naloxone; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase | 2005 |
L-type calcium channel blockade attenuates morphine withdrawal: in vivo interaction between L-type calcium channels and corticosterone.
Topics: Adrenalectomy; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Corticosterone; Drug Interactions; Hypothalamo-Hypophyseal System; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Nifedipine; Pituitary-Adrenal System; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 2008 |
Foot ulcers in systemic sclerosis escape surgical amputation.
Topics: Aged; Analgesics, Opioid; Anti-Bacterial Agents; Drug Therapy, Combination; Factor Xa Inhibitors; Female; Foot Ulcer; Humans; Iloprost; Naloxone; Nifedipine; Oxycodone; Rivaroxaban; Scleroderma, Systemic; Vasodilator Agents | 2020 |