nifedipine has been researched along with n-vinyl-2-pyrrolidinone in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.13) | 18.7374 |
| 1990's | 1 (2.56) | 18.2507 |
| 2000's | 16 (41.03) | 29.6817 |
| 2010's | 18 (46.15) | 24.3611 |
| 2020's | 2 (5.13) | 2.80 |
| Authors | Studies |
|---|---|
| Hirayama, F; Horiuchi, Y; Ikegami, K; Uekama, K; Wang, Z | 1 |
| Higashide, F; Mizumoto, T; Nozawa, Y | 1 |
| Kuchiki, A; Nakagawa, H; Sugimoto, I | 1 |
| Danjo, K; Hirasawa, N; Ishise, S; Miyata, H | 2 |
| Forster, A; Hempenstall, J; Rades, T | 1 |
| Aso, Y; Kojima, S; Yoshioka, S | 1 |
| Chen, SJ; Jia, YJ; Li, YH; Zhu, JB | 1 |
| Bodmeier, R; Friedrich, H; Nada, A | 1 |
| Bodmeier, R; Friedrich, H; Fussnegger, B; Kolter, K | 1 |
| Aso, Y; Yoshioka, S | 1 |
| Konno, H; Marsac, PJ; Taylor, LS | 1 |
| Marsac, PJ; Shamblin, SL; Taylor, LS | 1 |
| Aso, Y; Kawanishi, T; Miyazaki, T; Yoshioka, S | 1 |
| Ishida, H; Wu, T; Yu, L | 1 |
| Aso, Y; Hayashi, T; Kawanishi, T; Kitamura, S; Miyazaki, T; Muranushi, N; Takakura, A; Tanaka, K; Yoshioka, S | 1 |
| Konno, H; Marsac, PJ; Rumondor, AC; Taylor, LS | 1 |
| Liu, L; Xu, X | 1 |
| Sun, Y; Tao, J; Yu, L; Zhang, GG | 2 |
| Wei, YM; Yu, Y; Zhao, L; Zheng, WW | 1 |
| Bhugra, C; Caron, V; Pikal, MJ | 1 |
| Cai, T; Yu, L; Zhu, L | 1 |
| Itai, S; Iwao, Y; Kitamura, S; Mimura, H; Miyanishi, H; Mizuno, M; Nemoto, T; Noguchi, S | 1 |
| Mimura, H; Nasu, M; Nemoto, T; Sako, K | 1 |
| Agbaria, R; Beig, A; Dahan, A; Ioffe-Dahan, V; Miller, JM | 1 |
| Fujii, M; Kanada, K; Koizumi, N; Shibata, Y; Suzuki, A; Watanabe, Y; Yamada, M | 1 |
| Munson, EJ; Sperger, D; Yuan, X | 1 |
| Alonzo, DE; Gao, Y; Raina, SA; Taylor, LS; Zhang, GG | 1 |
| Kothari, K; Ragoonanan, V; Suryanarayanan, R | 1 |
| Kimura, S; Nagane, K; Ogawa, N; Takahashi, C; Ukai, K; Yamamoto, H | 1 |
| Goto, S; Kuroda, H; Makino, K; Nakajima, T; Shimakura, K; Takeuchi, I | 1 |
| Higashi, K; Moribe, K; Ueda, K | 1 |
| McKenna, GB; Mehta, M; Suryanarayanan, R | 1 |
| Gao, Y; Indulkar, AS; Mo, H; Raina, SA; Taylor, LS; Waters, JE; Zhang, GGZ | 1 |
| Ben Osman, Y; Liavitskaya, T; Vyazovkin, S | 1 |
| Huang, S; Liu, X; Lowinger, MB; Lu, X; Ma, X; Su, Y; Williams, RO | 1 |
| Brunsteiner, M; Gescheidt, G; Karn, A; Modhave, D; Neshchadin, D; Paudel, A; Roskar, R; Saraf, I | 1 |
| Castro-Camus, E; Heidrich, L; Keck, CM; Koch, M; Ornik, J | 1 |
39 other study(ies) available for nifedipine and n-vinyl-2-pyrrolidinone
| Article | Year |
|---|---|
Inhibitory effect of 2-hydroxypropyl-beta-cyclodextrin on crystal-growth of nifedipine during storage: superior dissolution and oral bioavailability compared with polyvinylpyrrolidone K-30.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Biological Availability; Crystallization; Cyclodextrins; Dogs; Drug Carriers; Microscopy, Electron; Nifedipine; Povidone; Tablets; X-Ray Diffraction | 1992 |
Increases in dissolution rate of nifedipine by roll mixing with polyvinylpyrrolidone.
Topics: Chemistry, Pharmaceutical; Drug Compounding; Nifedipine; Povidone; Solubility | 1986 |
Stability of Nifedipine-polyvinylpyrrolidone coprecipitate.
Topics: Animals; Dogs; Drug Stability; Nifedipine; Povidone; Pyridines | 1981 |
Physicochemical characterization and drug release studies of nilvadipine solid dispersions using water-insoluble polymer as a carrier.
Topics: Calorimetry, Differential Scanning; Carboxymethylcellulose Sodium; Cellulose; Crystallization; Dosage Forms; Drug Carriers; Microscopy, Electron, Scanning; Nifedipine; Povidone; Solubility; Spectroscopy, Fourier Transform Infrared; Time Factors; X-Ray Diffraction | 2003 |
Comparison of the Gordon-Taylor and Couchman-Karasz equations for prediction of the glass transition temperature of glass solutions of drug and polyvinylpyrrolidone prepared by melt extrusion.
Topics: Algorithms; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Differential Thermal Analysis; Humidity; Indomethacin; Nifedipine; Pharmaceutic Aids; Pharmaceutical Preparations; Povidone; Solubility; Temperature; Thermogravimetry; Tolbutamide | 2003 |
Molecular mobility-based estimation of the crystallization rates of amorphous nifedipine and phenobarbital in poly(vinylpyrrolidone) solid dispersions.
Topics: Algorithms; Calorimetry, Differential Scanning; Crystallization; Kinetics; Nifedipine; Pharmaceutic Aids; Phenobarbital; Povidone; Suspensions; Thermodynamics | 2004 |
Application of nilvadipine solid dispersion to tablet formulation and manufacturing using crospovidone and methylcellulose as dispersion carriers.
Topics: Drug Compounding; Drug Stability; Excipients; Hardness; Methylcellulose; Nifedipine; Particle Size; Povidone; Solubility; Tablets, Enteric-Coated | 2004 |
[Studies on combined release behaviors of versatile mini-tablets in capsule systems and fittings of their mathematical model].
Topics: Capsules; Delayed-Action Preparations; Drug Delivery Systems; Models, Chemical; Nifedipine; Polyethylene Glycols; Povidone; Solubility; Starch; Tablets | 2004 |
Solid state and dissolution rate characterization of co-ground mixtures of nifedipine and hydrophilic carriers.
Topics: Calcium Channel Blockers; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Gelatin; Hypromellose Derivatives; Methylcellulose; Microscopy, Electron, Scanning; Nifedipine; Particle Size; Poloxamer; Polyethylene Glycols; Povidone; Powder Diffraction; Sodium Dodecyl Sulfate; Solubility; Urea; X-Ray Diffraction | 2005 |
Dissolution rate improvement of poorly water-soluble drugs obtained by adsorbing solutions of drugs in hydrophilic solvents onto high surface area carriers.
Topics: Adsorption; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Drug Carriers; Excipients; Methanol; Nifedipine; Poloxamer; Polyethylene Glycols; Povidone; Pyrrolidinones; Silicon Dioxide; Solubility; Solvents; Surface Properties; Time Factors | 2006 |
Molecular mobility of nifedipine-PVP and phenobarbital-PVP solid dispersions as measured by 13C-NMR spin-lattice relaxation time.
Topics: Carbon Isotopes; Crystallization; Magnetic Resonance Spectroscopy; Molecular Conformation; Nifedipine; Phenobarbital; Povidone; Temperature | 2006 |
A comparison of the physical stability of amorphous felodipine and nifedipine systems.
Topics: Calcium Channel Blockers; Chemical Phenomena; Chemistry, Physical; Drug Stability; Entropy; Felodipine; Hydrogen Bonding; Kinetics; Membranes, Artificial; Nifedipine; Pharmaceutic Aids; Povidone; Spectrophotometry, Infrared; Temperature; Thermodynamics | 2006 |
Theoretical and practical approaches for prediction of drug-polymer miscibility and solubility.
Topics: Algorithms; Calcium Channel Blockers; Chemical Phenomena; Chemistry, Physical; Entropy; Felodipine; Forecasting; Models, Chemical; Nifedipine; Pharmaceutic Aids; Pharmaceutical Preparations; Polymers; Povidone; Solubility; Thermodynamics | 2006 |
Crystallization rate of amorphous nifedipine analogues unrelated to the glass transition temperature.
Topics: Calorimetry, Differential Scanning; Crystallization; Excipients; Hot Temperature; Hypromellose Derivatives; Methylcellulose; Nifedipine; Nitrendipine; Phase Transition; Polymers; Povidone; Temperature; Transition Temperature; Water | 2007 |
Sudden rise of crystal growth rate of nifedipine near T(g) without and with polyvinylpyrrolidone.
Topics: Calcium Channel Blockers; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Crystallography, X-Ray; Drug Stability; Excipients; Kinetics; Nifedipine; Phase Transition; Povidone; Solubility; Spectrum Analysis, Raman; Transition Temperature | 2007 |
Miscibility of nifedipine and hydrophilic polymers as measured by (1)H-NMR spin-lattice relaxation.
Topics: Calcium Channel Blockers; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Hypromellose Derivatives; Magnetic Resonance Spectroscopy; Methylcellulose; Nifedipine; Phenobarbital; Polymers; Povidone; Solubility | 2007 |
Recrystallization of nifedipine and felodipine from amorphous molecular level solid dispersions containing poly(vinylpyrrolidone) and sorbed water.
Topics: Crystallization; Drug Stability; Drug Storage; Felodipine; Humidity; Kinetics; Models, Chemical; Nifedipine; Povidone; Solubility; Solvents; Thermodynamics; Transition Temperature; Water; Wettability | 2008 |
Preparation of bilayer-core osmotic pump tablet by coating the indented core tablet.
Topics: Calcium Channel Blockers; Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Excipients; Kinetics; Membranes, Artificial; Nifedipine; Osmosis; Permeability; Polyethylene Glycols; Povidone; Sodium Chloride; Solubility; Tablets; Technology, Pharmaceutical | 2008 |
Solubility of small-molecule crystals in polymers: D-mannitol in PVP, indomethacin in PVP/VA, and nifedipine in PVP/VA.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Indomethacin; Kinetics; Mannitol; Nifedipine; Povidone; Pyrrolidines; Reproducibility of Results; Solubility; Solvents; Technology, Pharmaceutical; Transition Temperature; Vinyl Compounds; Viscosity | 2009 |
Polymer blends used to prepare nifedipine loaded hollow microspheres for a floating-type oral drug delivery system: in vitro evaluation.
Topics: Administration, Oral; Calcium Channel Blockers; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Stability; Ethanol; Ether; Hydrophobic and Hydrophilic Interactions; Kinetics; Microspheres; Models, Chemical; Nifedipine; Particle Size; Povidone; Solubility; Solvents; Surface Properties; Technology, Pharmaceutical | 2010 |
Prediction of onset of crystallization in amorphous pharmaceutical systems: phenobarbital, nifedipine/PVP, and phenobarbital/PVP.
Topics: Crystallization; Drug Stability; Models, Chemical; Nifedipine; Phenobarbital; Povidone; Transition Temperature | 2010 |
Solubilities of crystalline drugs in polymers: an improved analytical method and comparison of solubilities of indomethacin and nifedipine in PVP, PVP/VA, and PVAc.
Topics: Calorimetry, Differential Scanning; Chemistry Techniques, Analytical; Crystallization; Indomethacin; Nifedipine; Polyvinyls; Povidone; Solubility; Transition Temperature | 2010 |
Crystallization of organic glasses: effects of polymer additives on bulk and surface crystal growth in amorphous nifedipine.
Topics: Calorimetry, Differential Scanning; Crystallization; Drug Delivery Systems; Glass; Nifedipine; Phase Transition; Povidone; Spectrum Analysis, Raman; Surface Properties; Transition Temperature | 2011 |
Evaluation of crystallization behavior on the surface of nifedipine solid dispersion powder using inverse gas chromatography.
Topics: Calcium Channel Blockers; Chromatography, Gas; Crystallization; Drug Stability; Kinetics; Nifedipine; Povidone; Solubility; Surface Properties | 2013 |
Development of qualitative and quantitative analysis methods in pharmaceutical application with new selective signal excitation methods for 13 C solid-state nuclear magnetic resonance using 1 H T1rho relaxation time.
Topics: Acetaminophen; Antipyrine; beta-Cyclodextrins; Caffeine; Carbon Isotopes; Chemistry, Pharmaceutical; Crystallization; Drug Combinations; Excipients; Indomethacin; Lactose; Magnetic Resonance Spectroscopy; Nifedipine; Pharmaceutical Preparations; Phenacetin; Povidone; Protons; Pyridones; Signal Processing, Computer-Assisted; Technology, Pharmaceutical | 2013 |
The twofold advantage of the amorphous form as an oral drug delivery practice for lipophilic compounds: increased apparent solubility and drug flux through the intestinal membrane.
Topics: Administration, Oral; Animals; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallography, X-Ray; Desiccation; Drug Compounding; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Jejunum; Male; Membranes, Artificial; Methylcellulose; Nifedipine; Permeability; Povidone; Powder Diffraction; Pyrrolidines; Rats; Rats, Wistar; Solubility; Technology, Pharmaceutical; Time Factors; Vinyl Compounds | 2013 |
Effect of storage conditions on the recrystallization of drugs in solid dispersions with crospovidone.
Topics: Crystallization; Dipyridamole; Drug Carriers; Drug Stability; Hot Temperature; Humidity; Indomethacin; Nifedipine; Povidone | 2014 |
Investigating miscibility and molecular mobility of nifedipine-PVP amorphous solid dispersions using solid-state NMR spectroscopy.
Topics: Calorimetry, Differential Scanning; Excipients; Magnetic Resonance Spectroscopy; Nifedipine; Plasma Substitutes; Povidone; Solubility; Temperature; Vasodilator Agents | 2014 |
Impact of polymers on the crystallization and phase transition kinetics of amorphous nifedipine during dissolution in aqueous media.
Topics: Crystallization; Hypromellose Derivatives; Kinetics; Nifedipine; Phase Transition; Polymers; Povidone; Solubility; Spectrum Analysis, Raman | 2014 |
The role of polymer concentration on the molecular mobility and physical stability of nifedipine solid dispersions.
Topics: Crystallization; Drug Stability; Nifedipine; Polymers; Povidone; X-Ray Diffraction | 2015 |
Application of spherical silicate to prepare solid dispersion dosage forms with aqueous polymers.
Topics: Crystallization; Drug Liberation; Microspheres; Nifedipine; Particle Size; Povidone; Powders; Silicates; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Water | 2015 |
Estimation of Crystallinity of Nifedipine-Polyvinylpyrrolidone Solid Dispersion by Usage of Terahertz Time-Domain Spectroscopy and of X-Ray Powder Diffractometer.
Topics: Crystallization; Humidity; Nifedipine; Povidone; Powders; Regression Analysis; Temperature; Terahertz Spectroscopy; X-Ray Diffraction; X-Rays | 2015 |
Application of Solid-State NMR Relaxometry for Characterization and Formulation Optimization of Grinding-Induced Drug Nanoparticle.
Topics: Chemistry, Pharmaceutical; Crystallization; Drug Compounding; Hypromellose Derivatives; Magnetic Resonance Spectroscopy; Nanoparticles; Nifedipine; Povidone; Sodium Dodecyl Sulfate | 2016 |
Molecular mobility in glassy dispersions.
Topics: Crystallization; Drug Stability; Glass; Hydrogen Bonding; Methylcellulose; Nifedipine; Polymers; Povidone; Temperature | 2016 |
Origin of Nanodroplet Formation Upon Dissolution of an Amorphous Solid Dispersion: A Mechanistic Isotope Scrambling Study.
Topics: Calcium Channel Blockers; Crystallization; Drug Compounding; Excipients; Hypromellose Derivatives; Magnetic Resonance Spectroscopy; Nanostructures; Nifedipine; Povidone; Solubility; Vinyl Compounds | 2017 |
Polyvinylpyrrolidone affects thermal stability of drugs in solid dispersions.
Topics: Drug Stability; Felodipine; Indomethacin; Nifedipine; Povidone; Thermogravimetry | 2018 |
Influence of mechanical and thermal energy on nifedipine amorphous solid dispersions prepared by hot melt extrusion: Preparation and physical stability.
Topics: Drug Carriers; Drug Compounding; Drug Stability; Hot Temperature; Mechanical Phenomena; Nifedipine; Povidone; Solubility; Vinyl Compounds | 2019 |
Forced Solid-State Oxidation Studies of Nifedipine-PVP Amorphous Solid Dispersion.
Topics: Calorimetry, Differential Scanning; Nifedipine; Polymers; Povidone; Solubility | 2022 |
Polyvinylpyrrolidone as co-inhibitor of crystallization of nifedipine in paper tablets.
Topics: Crystallization; Drug Stability; Nifedipine; Povidone; Solubility; Tablets | 2023 |