nifedipine and morphine

nifedipine has been researched along with morphine in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (14.29)	18.7374
1990's	22 (34.92)	18.2507
2000's	25 (39.68)	29.6817
2010's	7 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Nagashima, R; Nishikawa, T; Tobita, M	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Battaglia, M; Pavone, F; Sansone, M	1
Bustamante, D; Fernandez, E; Kramer, V; Miranda, HF; Paeile, C; Pelissier, T; Pinardi, G; Saavedra, H	1
Kamei, J; Kasuya, Y	1
Schnur, P	1
Bapna, JS; Rajaram, S; Ramaswamy, S	1
Morrone, LA; Pimpinella, G; Romanelli, L; Valeri, P	1
Martinelli, B; Morrone, LA; Severini, C; Valeri, P	1
Olson, KG; Welch, SP	1
Argenton, S; Bianchi, M; Breda, M; Carta, F; Cervi, D; Fantoni, A; Marolla, G; Panerai, AE; Tamburini, M	1
Leza, JC; Lizasoain, I; Martin, MI	1
Orrego, F; Riveros, N	1
Kavaliers, M	1
Kavaliers, M; Ossenkopp, KP	1
Bustamante, D; Miranda, HF; Paeile, C; Pelissier, T	1
Bapna, JS; Rajasekaran, M; Ramaswamy, S	1
Argenton, S; Carta, F; Cervi, D; Fantoni, A; Marolla, G; Panerai, AE; Tamburini, M	1
Kameswaran, L; Krishnamurthy, V; Mythirayee, CI; Ramachandran, S; Ramaswamy, S; Thirugnanasambantham, P; Viswanathan, S	1
Inoki, R; Matsumoto, K; Ohnishi, T; Saito, K; Sakuda, M	1
Dall'olio, R; Gaggi, R; Gianni, AM; Roncada, P	1
Antkiewicz-Michaluk, L; Michaluk, J; Romańska, I; Vetulani, J	2
Kimura, M; Kobayashi, D; Matsuzawa, T; Morimoto, Y; Sugibayashi, K	1
Harris, RL; McCabe, J; Sacchetti, A; Torres, M	1
Dos Reis, MP; Pereira, IT; Prado, WA	1
Amico, MC; Morrone, LA; Romanelli, L; Valeri, P	1
Biała, G; Langwiński, R	1
Abdollahi, M; Etemad, F; Nikfar, S; Sarkarati, F	1
Antkiewicz-Michaluk, L; Karolewicz, B; Michaluk, J; Vetulani, J	1
Carmichael, FJ; Christoff, B; Er, SS; Ning, J; Wong, LT	1
Ahtee, L; Kivastik, T; Piepponen, TP; Zharkovsky, A	1
Szulczyk, P	1
Adame, M; Carrascosa, F; Fidalgo, I; Iribarren, MJ; Monedero, P; Sáez-Fernández, AN; Zarauza, R	1
Li, JX; Liang, JH; Liu, RK; Zhang, Q; Zheng, JW	1
Bywater, RA; Powell, AK	1
Mitcheva, M; Vitcheva, V	1
Ahmadiani, A; Esmaeili Mahani, S; Javan, M; Motamedi, F	1
Ahmadiani, A; Esmaeili Mahani, S; Khaksari, M; Motamedi, F; Pourshanazari, A; Vahedi, S	1
Li, J; Liu, Y; Lu, XQ; Piletz, JE; Qin, BY; Su, RB; Wu, N; Xu, B; Zheng, JQ	1
Ahmadiani, A; Esmaeili-Mahani, S; Fereidoni, M; Javan, M; Maghsoudi, N; Motamedi, F	1
Ahmadiani, A; Esmaeili-Mahani, S; Khaksari, M; Motamedi, F; Pourshanazari, A; Vahedi, S	1
Ahmadiani, A; Esmaeili-Mahani, S; Javan, M; Koibuchi, N; Maghsoudi, N; Motamedi, F; Shimokawa, N	1
Ahmadiani, A; Esmaeili-Mahani, S; Fathi, Y; Hosseinpanah, F; Motamedi, F	1
Gupta, A; Mishra, P; Ray, SB; Verma, D; Wadhwa, S	1
Dkhar, SA; Krishna, PR; Ramaswamy, S; Sandhiya, S	1
Kurokawa, K; Ohkuma, S; Shibasaki, M	1
Joukar, F; Joukar, S; Sheibani, M	1

Reviews

2 review(s) available for nifedipine and morphine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Anatomic and functional identification of sensory neurons in neurophysiologic studies]. Postepy higieny i medycyny doswiadczalnej, 2000, Volume: 54, Issue:3 Topics: Action Potentials; Animals; Humans; Ion Channels; Mechanoreceptors; Morphine; Motor Neurons; Neurons, Afferent; Nifedipine; Patch-Clamp Techniques; Sympathetic Nervous System	2000

Trials

3 trial(s) available for nifedipine and morphine

Article	Year
[Potentiation of morphine analgesia by nifedipine in postoperative pain]. Minerva anestesiologica, 1988, Volume: 54, Issue:4 Topics: Adult; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Middle Aged; Morphine; Nifedipine; Pain, Postoperative	1988
Enhancement of the epidural morphine-induced analgesia by systemic nifedipine. Pain, 1993, Volume: 53, Issue:3 Topics: Administration, Sublingual; Adult; Age Factors; Aged; Analgesia, Epidural; Blood Pressure; Body Weight; Double-Blind Method; Drug Synergism; Female; Genitalia, Female; Heart Rate; Humans; Middle Aged; Morphine; Nifedipine; Pain, Postoperative	1993
A comparative study with oral nifedipine, intravenous nimodipine, and magnesium sulfate in postoperative analgesia. Anesthesia and analgesia, 2000, Volume: 91, Issue:4 Topics: Administration, Oral; Adult; Aged; Analgesics; Analgesics, Opioid; Analysis of Variance; Calcium Channel Blockers; Chi-Square Distribution; Colon; Double-Blind Method; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Intravenous; Magnesium Sulfate; Male; Middle Aged; Morphine; Nifedipine; Nimodipine; Pain Measurement; Pain, Postoperative; Placebos; Receptors, N-Methyl-D-Aspartate; Rectum	2000

Other Studies

58 other study(ies) available for nifedipine and morphine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Nifedipine-morphine interaction: a further investigation on nociception and locomotor activity in mice. The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:9 Topics: Animals; Drug Interactions; Hydralazine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Motor Activity; Nifedipine; Nociceptors; Pain Measurement	1992
Antinociceptive effects of Ca2+ channel blockers. European journal of pharmacology, 1992, Jul-07, Volume: 217, Issue:2-3 Topics: Analgesics; Analysis of Variance; Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Mice; Morphine; Nifedipine; Nimodipine; Pain Measurement; Rats; Rats, Wistar; Verapamil	1992
Antitussive effects of Ca2+ channel antagonists. European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1 Topics: Animals; Antitussive Agents; Calcium Channel Blockers; Capsaicin; Codeine; Cough; Dextromethorphan; Drug Interactions; Drug Synergism; Flunarizine; Guinea Pigs; Male; Morphine; Nifedipine; Verapamil	1992
Morphine withdrawal in the hamster. Annals of the New York Academy of Sciences, 1992, Jun-28, Volume: 654 Topics: Animals; Clonidine; Cricetinae; Morphine; Naloxone; Nifedipine; Stereotyped Behavior; Substance Withdrawal Syndrome; Verapamil	1992
Role of calcium in the analgesic action of tetrahydroisoxazolepyridinol and muscimol. The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:6 Topics: Analgesics; Animals; Calcium; Calcium Chloride; Isoxazoles; Male; Mice; Morphine; Muscimol; Nifedipine	1991
Some pharmacological characteristics of the guinea pig ileum opioid system activated by cholecystokinin. Neuropharmacology, 1990, Volume: 29, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Cholecystokinin; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Receptors, Opioid; Yohimbine	1990
Reproducible withdrawal contractions of isolated guinea-pig ileum after brief morphine exposure: effects of clonidine and nifedipine. The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Substance Withdrawal Syndrome; Yohimbine	1990
Opiate tolerance-induced modulation of free intracellular calcium in synaptosomes. Life sciences, 1991, Volume: 48, Issue:19 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Administration, Oral; Animals; Brain; Brain Chemistry; Calcium; Calcium Channels; Drug Administration Schedule; Drug Tolerance; Intracellular Fluid; Mice; Morphine; Narcotics; Nifedipine; Potassium Chloride; Synaptosomes	1991
Effect of nifedipine on morphine-induced analgesia. Anesthesia and analgesia, 1990, Volume: 70, Issue:5 Topics: Adult; Animals; Blood Pressure; Drug Synergism; Female; Heart Rate; Humans; Middle Aged; Morphine; Nifedipine; Pain, Postoperative; Rats; Rats, Inbred Strains	1990
Calcium channel blockers: effect on morphine-induced hypermotility. Psychopharmacology, 1990, Volume: 101, Issue:2 Topics: Animals; Calcium Channel Blockers; Dextroamphetamine; Diltiazem; Male; Mice; Morphine; Motor Activity; Nifedipine	1990
N-methylaspartate-activated calcium channels in rat brain cortex slices. Effect of calcium channel blockers and of inhibitory and depressant substances. Neuroscience, 1986, Volume: 17, Issue:3 Topics: Animals; Aspartic Acid; Cadmium; Calcium Channel Blockers; Central Nervous System Depressants; Cerebral Cortex; Cobalt; gamma-Aminobutyric Acid; Ion Channels; Morphine; N-Methylaspartate; Nifedipine; Rats; Tetrodotoxin; Time Factors	1986
Calcium channel blockers inhibit the antagonistic effects of Phe-Met-Arg-Phe-amide (FMRFamide) on morphine- and stress-induced analgesia in mice. Brain research, 1987, Jul-14, Volume: 415, Issue:2 Topics: Animals; Calcium; Drug Interactions; FMRFamide; Ion Channels; Mice; Morphine; Nervous System; Neuropeptides; Nifedipine; Pain; Stress, Physiological; Verapamil	1987
Magnetic fields inhibit opioid-mediated 'analgesic' behaviours of the terrestrial snail, Cepaea nemoralis. Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 1988, Volume: 162, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Calcium; Diltiazem; Ion Channels; Magnetics; Morphine; Naloxone; Nifedipine; Nociceptors; Pyrrolidines; Snails; Temperature; Verapamil	1988
Analgesic action of clonixin, nifedipine and morphine using the formalin test. General pharmacology, 1989, Volume: 20, Issue:3 Topics: Analgesics; Animals; Clonixin; Drug Tolerance; Female; Formaldehyde; Lethal Dose 50; Male; Mice; Morphine; Nicotinic Acids; Nifedipine; Pain Measurement; Rats	1989
Role of calcium in prolactin analgesia. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 283, Issue:1 Topics: Analgesics; Animals; Calcium; Calcium Chloride; Clonidine; Male; Mice; Morphine; Nifedipine; Prolactin; Thyrotropin-Releasing Hormone	1986
Involvement of calcium in flavonoid analgesia. European journal of pharmacology, 1988, Aug-02, Volume: 152, Issue:3 Topics: Analgesics; Animals; Calcium; Flavonoids; Male; Mice; Morphine; Nifedipine	1988
Decrease in analgesic effect of nifedipine following chronic morphine administration. European journal of pharmacology, 1988, Dec-06, Volume: 158, Issue:1-2 Topics: Acetates; Acetic Acid; Analgesics; Animals; Brain; Calcium; Drug Tolerance; Male; Mice; Mice, Inbred ICR; Morphine; Nifedipine	1988
Interaction between dihydropyridine calcium antagonists and morphine on the brain biogenic amines. General pharmacology, 1994, Volume: 25, Issue:5 Topics: Animals; Biogenic Amines; Brain; Calcium Channel Blockers; Dopamine; Drug Interactions; Male; Morphine; Nifedipine; Nimodipine; Nisoldipine; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin	1994
Differential involvement of voltage-dependent calcium channels in apomorphine-induced hypermotility and stereotypy. Psychopharmacology, 1994, Volume: 113, Issue:3-4 Topics: Animals; Apomorphine; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Electroshock; Male; Morphine; Motor Activity; Nifedipine; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome; Up-Regulation	1994
Reduction of morphine dependence and potentiation of analgesia by chronic co-administration of nifedipine. Psychopharmacology, 1993, Volume: 111, Issue:4 Topics: Analgesics; Animals; Cerebral Cortex; Drug Interactions; Drug Tolerance; Male; Morphine; Morphine Dependence; Nifedipine; Pain Measurement; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Opioid; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Weight Gain	1993
Analysis of the combined effect of 1-menthol and ethanol as skin permeation enhancers based on a two-layer skin model. Pharmaceutical research, 1994, Volume: 11, Issue:1 Topics: Animals; Atenolol; Chromatography, High Pressure Liquid; Ethanol; In Vitro Techniques; Male; Menthol; Models, Biological; Morphine; Nifedipine; Rats; Rats, Inbred Strains; Skin; Skin Absorption; Solubility; Stimulation, Chemical; Vinca Alkaloids	1994
ED management of acute congestive heart failure in renal dialysis patients. The American journal of emergency medicine, 1993, Volume: 11, Issue:6 Topics: Acute Disease; Administration, Cutaneous; Administration, Oral; Administration, Sublingual; Captopril; Clinical Protocols; Clonidine; Emergency Medical Services; Emergency Medicine; Heart Failure; Humans; Infusions, Intravenous; Intubation, Intratracheal; Kidney Failure, Chronic; Morphine; Nifedipine; Nitroglycerin; Nitroprusside; Oxygen Inhalation Therapy; Peritoneal Dialysis; Prospective Studies; Renal Dialysis; Severity of Illness Index; Transportation of Patients	1993
Withdrawal contractures of guinea-pig isolated ileum after acute activation of kappa-opioid receptors. British journal of pharmacology, 1993, Volume: 109, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Nifedipine; Pyrrolidines; Receptors, Opioid, kappa; Substance Withdrawal Syndrome	1993
Effects of calcium channel antagonists on the reinforcing properties of morphine, ethanol and cocaine as measured by place conditioning. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1996, Volume: 47, Issue:3 Topics: Animals; Calcium; Calcium Channel Blockers; Cocaine; Conditioning, Psychological; Ethanol; Male; Morphine; Nifedipine; Rats; Rats, Wistar; Reward; Substance-Related Disorders	1996
Interaction between calcium channel blockers and sweetening agents on morphine-induced analgesia in mice by formalin test. General pharmacology, 1998, Volume: 31, Issue:3 Topics: Analgesics; Animals; Aspartame; Calcium Channel Blockers; Diltiazem; Drug Interactions; Male; Mice; Morphine; Nifedipine; Pain Measurement; Saccharin; Sucrose; Sweetening Agents; Verapamil	1998
Effects of various Ca2+ channel antagonists on morphine analgesia, tolerance and dependence, and on blood pressure in the rat. European journal of pharmacology, 1998, Jul-10, Volume: 352, Issue:2-3 Topics: Analgesics, Opioid; Animals; Binding Sites; Blood Pressure; Calcium Channel Blockers; Cerebral Cortex; Drug Interactions; Drug Tolerance; Male; Morphine; Nifedipine; Nimodipine; Nitrendipine; Rats; Rats, Wistar; Substance-Related Disorders; Tritium; Verapamil	1998
Hemolink-induced effects on intestinal motor function and attenuation of these effects by selected agents. Artificial cells, blood substitutes, and immobilization biotechnology, 1998, Volume: 26, Issue:5-6 Topics: Analgesics, Opioid; Animals; Arginine; Gastrointestinal Motility; Glycopyrrolate; Hemodynamics; Hemoglobins; Humans; Infusions, Intravenous; Jejunum; Male; Morphine; Nifedipine; Nitroglycerin; Raffinose; Rats; Rats, Wistar	1998
Effects of morphine in rats withdrawn from repeated nifedipine administration. European journal of pharmacology, 1999, Jan-22, Volume: 365, Issue:2-3 Topics: Animals; Behavior, Animal; Body Temperature; Brain; Calcium Channel Blockers; Catalepsy; Dihydropyridines; Dopamine; Drug Interactions; In Vitro Techniques; Male; Morphine; Nifedipine; Pain Measurement; Rats; Serotonin; Substance Withdrawal Syndrome; Time Factors	1999
L-type Ca(2+) channel blockers inhibit the development but not the expression of sensitization to morphine in mice. European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3 Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Mice; Morphine; Motor Activity; Narcotic Antagonists; Narcotics; Nifedipine; Nimodipine; Verapamil	2003
Murine intestinal migrating motor complexes: longitudinal components. Neurogastroenterology and motility, 2003, Volume: 15, Issue:3 Topics: Anesthetics, Local; Animals; Free Radical Scavengers; Ganglionic Blockers; Gastrointestinal Motility; Hexamethonium; Intestines; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Myoelectric Complex, Migrating; Nifedipine; Nitric Oxide; Organ Culture Techniques; Serotonin; Tetrodotoxin; Vasodilator Agents	2003
Effects of nifedipine on behavioral and biochemical parameters in rats after multiple morphine administration. Methods and findings in experimental and clinical pharmacology, 2004, Volume: 26, Issue:8 Topics: Analgesics, Opioid; Animals; Behavior, Animal; Brain; Calcium Channel Blockers; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Interactions; Male; Microsomes; Microsomes, Liver; Morphine; Morphine Dependence; Nerve Tissue Proteins; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Substance Withdrawal Syndrome	2004
Involvement of hypothalamic pituitary adrenal axis on the effects of nifedipine in the development of morphine tolerance in rats. Pharmacology, biochemistry, and behavior, 2005, Volume: 81, Issue:1 Topics: Adrenalectomy; Animals; Corticosterone; Drug Combinations; Drug Tolerance; Hypothalamo-Hypophyseal System; Male; Morphine; Nifedipine; Pain Measurement; Pituitary-Adrenal System; Rats; Rats, Wistar	2005
Nifedipine potentiates antinociceptive effects of morphine in rats by decreasing hypothalamic pituitary adrenal axis activity. Pharmacology, biochemistry, and behavior, 2005, Volume: 82, Issue:1 Topics: Adrenal Glands; Analgesics, Opioid; Animals; Corticosterone; Hypothalamo-Hypophyseal System; Male; Morphine; Nifedipine; Pituitary-Adrenal System; Rats; Rats, Wistar	2005
IRAS, a candidate for I1-imidazoline receptor, mediates inhibitory effect of agmatine on cellular morphine dependence. Biochemical pharmacology, 2005, Oct-01, Volume: 70, Issue:7 Topics: Agmatine; Animals; CHO Cells; Cricetinae; Cyclic AMP; Dizocilpine Maleate; Imidazoles; Imidazoline Receptors; Intracellular Signaling Peptides and Proteins; Morphine; Naloxone; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase	2005
Nifedipine suppresses morphine-induced thermal hyperalgesia: evidence for the role of corticosterone. European journal of pharmacology, 2007, Jul-12, Volume: 567, Issue:1-2 Topics: Adrenalectomy; Analgesics, Opioid; Animals; Calcium Channel Blockers; Corticosterone; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Hypothalamo-Hypophyseal System; Male; Morphine; Nifedipine; Pain Threshold; Pituitary-Adrenal System; Rats; Rats, Wistar	2007
Involvement of hypothalamic pituitary adrenal axis on the analgesic cross-tolerance between morphine and nifedipine. Pharmacology, biochemistry, and behavior, 2007, Volume: 86, Issue:4 Topics: Adrenalectomy; Analgesics, Opioid; Animals; Calcium Channel Blockers; Corticosterone; Drug Tolerance; Hypothalamo-Hypophyseal System; Male; Morphine; Nifedipine; Pain Measurement; Pituitary-Adrenal System; Rats; Rats, Wistar	2007
Low-dose morphine induces hyperalgesia through activation of G alphas, protein kinase C, and L-type Ca 2+ channels in rats. Journal of neuroscience research, 2008, Feb-01, Volume: 86, Issue:2 Topics: Alkaloids; Analgesics, Opioid; Animals; Benzophenanthridines; Calcium Channel Blockers; Calcium Channels, L-Type; Carbazoles; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression; GTP-Binding Proteins; Hyperalgesia; Immunoblotting; Indoles; Male; Morphine; Nifedipine; Polymerase Chain Reaction; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; RNA, Messenger; Spinal Cord	2008
L-type calcium channel blockade attenuates morphine withdrawal: in vivo interaction between L-type calcium channels and corticosterone. Hormones and behavior, 2008, Volume: 53, Issue:2 Topics: Adrenalectomy; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Corticosterone; Drug Interactions; Hypothalamo-Hypophyseal System; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Nifedipine; Pituitary-Adrenal System; Rats; Rats, Wistar; Substance Withdrawal Syndrome	2008
Nimodipine is more effective than nifedipine in attenuating morphine tolerance on chronic co-administration in the rat tail-flick test. Indian journal of experimental biology, 2008, Volume: 46, Issue:4 Topics: Analgesics, Opioid; Animals; Behavior, Animal; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Male; Morphine; Nifedipine; Nimodipine; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Restraint, Physical	2008
Role of ion channel modifiers in reversal of morphine-induced gastrointestinal inertia by prokinetic agents in mice. Indian journal of experimental biology, 2008, Volume: 46, Issue:1 Topics: Analgesics, Opioid; Animals; Benzamides; Calcium Channels; Domperidone; Gastrointestinal Tract; Glyburide; Intestine, Small; Ion Channels; Kinetics; Mice; Minoxidil; Morphine; Morpholines; Nifedipine; Time Factors	2008
Upregulation of L-type Ca(v)1 channels in the development of psychological dependence. Synapse (New York, N.Y.), 2010, Volume: 64, Issue:6 Topics: Animals; Brain; Brain Chemistry; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cocaine; Disease Models, Animal; Frontal Lobe; Limbic System; Male; Methamphetamine; Mice; Morphine; Nifedipine; Substance-Related Disorders; Up-Regulation	2010
Cardiovascular effect of nifedipine in morphine dependent rats: hemodynamic, histopathological, and biochemical evidence. Croatian medical journal, 2012, Volume: 53, Issue:4 Topics: Analgesics, Opioid; Animals; Blood Pressure; Calcium Channel Blockers; Dimethyl Sulfoxide; Heart Injuries; Heart Rate; Isoproterenol; Male; Morphine; Morphine Dependence; Nifedipine; Rats; Rats, Wistar; Troponin I	2012