nifedipine and mifepristone

nifedipine has been researched along with mifepristone in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.53)18.2507
2000's7 (36.84)29.6817
2010's8 (42.11)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Burk, O; Eichelbaum, M; Geick, A1
Evans, CA; Jolivette, LJ; Nagilla, R; Ward, KW1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Delansorne, R; el Alj, A; Ferre, F; Germain, G; Lallaoui, H; Winer, N1
Descomps, B; Lobaccaro-Henri, C; Thaler-Dao, H1
Joëls, M; Krugers, H; Pu, Z; Shor, S; Wiegert, O1
Marks, B; Raucy, J; Trubetskoy, O; Yueh, MF; Zielinski, T1
Aguilar, R; Bellido, C; Garrido-Gracia, JC; Sánchez-Criado, JE1
Falkay, G; Gáspár, R; Hajagos-Tóth, J; Kormányos, Z; Pál, A1
Agarwal, AK; Beech, DJ; Fishwick, CW; Green, BL; Jiang, S; Majeed, Y; Muraki, K; Naylor, J; O'Regan, DJ; Picton, HM; Porter, KE; Seymour, VA; Tumova, S; Woods, DM1
Capuano, V; Ferron, L; Renaud, JF; Ruchon, Y; Sankhe, S1
Okada, H; Yasuda, K; Yoshida, A1
Boatwright, N; Crockett, SL; De, D; Hansen, CJ; Herington, JL; Newton, J; Paria, BC; Reese, J; Rogers, JH; Simpson, CL; Siricilla, S; Sulikowski, GA; Waterson, AG1

Reviews

1 review(s) available for nifedipine and mifepristone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

18 other study(ies) available for nifedipine and mifepristone

ArticleYear
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
    The Journal of biological chemistry, 2001, May-04, Volume: 276, Issue:18

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Dimerization; DNA; DNA Primers; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestines; Molecular Sequence Data; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Rifampin; Transcription Factors

2001
Extrapolation of preclinical pharmacokinetics and molecular feature analysis of "discovery-like" molecules to predict human pharmacokinetics.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

    Topics: Animals; Biometry; Dogs; Drug Evaluation, Preclinical; Haloperidol; Haplorhini; Humans; Injections, Intravenous; Liver; Liver Circulation; Metabolic Clearance Rate; Mifepristone; Molecular Structure; Molecular Weight; Rats; Reproducibility of Results

2006
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Progesterone and mifepristone modify principally the responses of circular myometrium to oxytocin in preparturient rats: comparison with responses to acetylcholine and to calcium.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:3

    Topics: Acetylcholine; Animals; Calcium; Drug Interactions; Female; In Vitro Techniques; Labor, Induced; Mifepristone; Myometrium; Nifedipine; Oxytocin; Pregnancy; Progesterone; Rats; Rats, Wistar; Receptors, Muscarinic

1993
RU 38486 inhibits intracellular calcium mobilization and PGI2 release from human myometrium: mechanisms of action.
    The Journal of steroid biochemistry and molecular biology, 1996, Volume: 59, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Abortifacient Agents, Steroidal; Arginine Vasopressin; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Drug Synergism; Endoplasmic Reticulum; Enzyme Inhibitors; Epoprostenol; Female; Gallic Acid; Hormone Antagonists; Humans; Intracellular Fluid; Mifepristone; Muscle Relaxation; Myometrium; Nifedipine; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Staurosporine; Structure-Activity Relationship; Thapsigargin; Uterine Contraction

1996
Glucocorticoid receptor activation selectively hampers N-methyl-D-aspartate receptor dependent hippocampal synaptic plasticity in vitro.
    Neuroscience, 2005, Volume: 135, Issue:2

    Topics: Animals; Calcium Channel Blockers; Corticosterone; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; Hormone Antagonists; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mifepristone; Neuronal Plasticity; Nifedipine; Patch-Clamp Techniques; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Valine

2005
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
    The AAPS journal, 2005, Mar-04, Volume: 7, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Clotrimazole; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Enzyme Induction; Genes, Reporter; Genes, Synthetic; Humans; Ketoconazole; Liver Neoplasms; Lovastatin; Luciferases; Mifepristone; Neoplasm Proteins; Nifedipine; Omeprazole; Paclitaxel; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Thiazolidinediones; Transcription, Genetic; Troglitazone; Troleandomycin

2005
Protein kinase C cross-talk with gonadotrope progesterone receptor is involved in GnRH-induced LH secretion.
    Journal of physiology and biochemistry, 2006, Volume: 62, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bodily Secretions; Cells, Cultured; Chelating Agents; Colforsin; Egtazic Acid; Enzyme Inhibitors; Female; Gonadotropin-Releasing Hormone; Imines; Indoles; Ionomycin; Luteinizing Hormone; Maleimides; Mifepristone; Nifedipine; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Receptors, Progesterone; Signal Transduction; Tetradecanoylphorbol Acetate

2006
Potentiation of the uterus-relaxing effects of β-adrenergic agonists with nifedipine: studies on rats and the human myometrium.
    Acta obstetricia et gynecologica Scandinavica, 2010, Volume: 89, Issue:10

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Drug Synergism; Drug Therapy, Combination; Female; Humans; Mifepristone; Models, Animal; Myometrium; Nifedipine; Oxytocics; Pregnancy; Premature Birth; Progesterone; Rats; Rats, Sprague-Dawley; Salmeterol Xinafoate; Tocolysis; Tocolytic Agents; Uterine Contraction

2010
Pregnenolone sulphate-independent inhibition of TRPM3 channels by progesterone.
    Cell calcium, 2012, Volume: 51, Issue:1

    Topics: Adrenal Cortex Hormones; Animals; Calcium Signaling; Cattle; Dihydrotestosterone; Estradiol; Female; Granulosa Cells; HEK293 Cells; Humans; Ion Channel Gating; Mifepristone; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; Pregnenolone; Progesterone; Protein Binding; Receptors, Progesterone; TRPM Cation Channels

2012
T-type Ca²⁺ signalling downregulates MEK1/2 phosphorylation and cross-talk with the RAAS transcriptional response in cardiac myocytes.
    Journal of molecular and cellular cardiology, 2012, Volume: 53, Issue:2

    Topics: Animals; Calcium Signaling; Flunarizine; Fluoxetine; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mibefradil; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Nifedipine; Phosphorylation; Rats; Rats, Wistar; Receptors, Glucocorticoid; Renin-Angiotensin System; Spironolactone

2012
Conflicting Nongenomic Effects of Progesterone in the Myometrium of Pregnant Rats.
    International journal of molecular sciences, 2021, Feb-22, Volume: 22, Issue:4

    Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Female; Hormone Antagonists; Mifepristone; Myometrium; Nifedipine; Organ Culture Techniques; Oxytocin; Potassium Chloride; Pregnancy; Progesterone; Pyrroles; Rats, Wistar; Uterine Contraction; Verapamil

2021
Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy.
    Pharmacological research, 2023, Volume: 195

    Topics: Animals; Biological Products; Female; Humans; Infant, Newborn; Mice; Mifepristone; Nifedipine; Obstetric Labor, Premature; Premature Birth; Tocolytic Agents

2023