nifedipine and mibefradil

nifedipine has been researched along with mibefradil in 78 studies

Research

Studies (78)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	18 (23.08)	18.2507
2000's	35 (44.87)	29.6817
2010's	23 (29.49)	24.3611
2020's	2 (2.56)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Keserü, GM	1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M	1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN	1
Clozel, JP; Hess, P; Véniant, M; Wolfgang, R	1
Himori, N; Sato, Y; Watanabe, H	1
Archambault, F; Dalle Ave, S; Lacourcière, Y; Lefebvre, J; Lindberg, E; Poirier, L; Ward, C	1
Böhm, M; Cremers, B; Flesch, M; Südkamp, M	1
Nakagawa, M; Sasaki, S	1
Kobrin, I; Lacourcière, Y; Massie, BM; Viskoper, R; Woittiez, A	1
Charlon, V; Kobrin, I; Lindberg, E; Pordy, R	1
Pitt, B	1
Kobrin, I	1
Conlin, PR; Williams, GH	1
Bailey, R; Huysmans, FT; Kobrin, I; Mion Júnior, D; Robson, RA; Villa, G; Woittiez, AJ	1
Koen, R; Lacolley, P; Levy, BI; Poitevin, P	1
Brixius, K; Hoischen, S; Mohr, V; Müller-Ehmsen, J; Münch, G; Schwinger, RH	1
Pordy, R; Woittiez, A	1
Fagard, R; Lijnen, P; Petrov, V	2
Lijnen, P; Petrov, V	1
Martini, M; Rispoli, G; Rossi, ML; Rubbini, G	1
Ceric, F; Kerr, B; Kong, M; Morales, P; Pizarro, E; Vigil, P	1
Protas, L; Robinson, RB	1
Han, CT; Lee, JH; Son, WY	1
Duggan, JA; Tabrizchi, R	2
Hill, MA; Kotecha, N; Murphy, TV; Potocnik, SJ	1
Esler, MD; Kamen, PW; Krum, H; Lim, S; Pellizzer, AM	1
Darné, B; Démolis, JL; Funck-Brentano, C; Jaillon, P; Ragueneau, I; Sao, AB	1
Himmel, HM; Ravens, U; Stengel, W	1
Hayashi, K; Honda, M; Kubota, E; Matsuda, H; Okubo, K; Ozawa, Y; Saruta, T; Tokuyama, H	1
Fujiwara, K; Hayashi, K; Nagahama, T; Ozawa, Y; Saruta, T	1
Hayashi, K; Honda, M; Kubota, E; Matsuda, H; Okubo, K; Ozawa, Y; Saruta, T; Takamatsu, I; Tokuyama, H	1
Asokan, KT; Mishra, SK; Raviprakash, V; Sarkar, SN	1
Anderson, UA; Bradley, JE; Hollywood, MA; McHale, NG; Thornbury, KD; Woolsey, SM	1
Holstein-Rathlou, NH; Jensen, BL; Jensen, LJ; Salomonsson, M	1
Al-Mehdi, AB; Chatterjee, S; Fisher, AB; Manevich, Y; Wei, Z	1
Kito, Y; Sanders, KM; Ward, SM	1
Clarkson, CW; Huang, L; Keyser, BM; Li, M; Taylor, JT; Zhuang, H	1
Hayashi, K; Homma, K; Kanda, T; Kumagai, H; Okubo, K; Ozawa, Y; Saruta, T; Takamatsu, I; Tatematsu, S; Wakino, S	1
Bieger, D; Ford, C; Mong, K; Tabrizchi, R	1
Badawi, JK; Bross, S; Kamp, S; Kwon, ST; Langbein, S; Li, H	1
Hadama, T; Kaku, T; Lee, TS; Miyamoto, S; Ono, K; Perez-Reyes, E; Takebayashi, S; Uchino, T	1
Cabrera, JA; Hong, F; Hong, Z; Nelson, DP; Olschewski, A; Varghese, A; Weir, EK	1
Black, N; Dhamija, S; Kowala, MC; Liachenko, S; Madore, S; Major, TC; Morenko, B; Okerberg, C; Sobocinski, G; Tinholt, P	1
Ball, CJ; Beltrame, JF; Saint, DA; Turner, SP; Wilson, DP	1
Godfraind, T	1
Cagney, V; Hollywood, M; Large, R; McCloskey, C; McHale, N; Sergeant, G; Thornbury, K	1
Amobi, N; Guillebaud, J; Smith, CH	1
Cao, C; Khurana, S; Lin, H; Pallone, TL; Zhang, Z	1
Cribbs, LL; Hansen, PB; Jensen, BL; Marcussen, N; Poulsen, CB; Skøtt, O; Walter, S	1
Braunstein, TH; Giese, I; Holstein-Rathlou, NH; Salomonsson, M; Sorensen, CM	1
Capuano, V; Ferron, L; Renaud, JF; Ruchon, Y; Sankhe, S	1
Bao, XX; Wang, JL; Wei, LH	1
Stengl, M; Wei, H	1
Dulon, D; Levic, S	1
Akerman, KE; Castrén, ML; Hakala, E; Jansson, LC; Louhivuori, LM; Louhivuori, V; Nordström, T; Wigren, HK	1
Fukunaga, K; Han, F; Moriguchi, S; Shioda, N; Yamamoto, Y	1
Chitaley, K; Jiang, X; Luttrell, I; Yang, CC	1
Lee, S; Roizes, S; von der Weid, PY	1
Cantí, C; Das, A; Herreros, J; Nàger, M; Pamplona, R; Purroy, R; Pushparaj, C	1
Batarfi, M; Jaffer, S; Luke, G; Patel, K; Valasek, P; Whalley, BJ	1
Hashitani, H; Mitsui, R	1
Chuang, JY; Hsu, TI; Kao, TJ; Limanjaya, I	1
Chadjichristos, CE; Chatziantoniou, C; Helle, F; Hultström, M; Iversen, B; Kavvadas, P	1

Reviews

3 review(s) available for nifedipine and mibefradil

Article	Year
[Calcium channel blocker for therapy of patients with hypertension]. Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55, Issue:8 Topics: Benzimidazoles; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Humans; Hypertension; Mibefradil; Nifedipine; Tetrahydronaphthalenes; Thiazoles	1997
Diversity of calcium antagonists. Clinical therapeutics, 1997, Volume: 19 Suppl A Topics: Angina Pectoris; Arteriosclerosis; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Kidney Failure, Chronic; Mibefradil; Nifedipine; Tetrahydronaphthalenes; Verapamil	1997
Use of calcium channel blockers in hypertension. Advances in internal medicine, 1998, Volume: 43 Topics: Antihypertensive Agents; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Case-Control Studies; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Heart Diseases; Humans; Hypertension; Longitudinal Studies; Mibefradil; Nifedipine; Public Health; Randomized Controlled Trials as Topic; Risk Factors; Tetrahydronaphthalenes; Vasodilator Agents; Verapamil	1998

Trials

8 trial(s) available for nifedipine and mibefradil

Article	Year
The antihypertensive efficacy of the novel calcium antagonist mibefradil in comparison with nifedipine GITS in moderate to severe hypertensives with ambulatory hypertension. American journal of hypertension, 1997, Volume: 10, Issue:2 Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Body Weight; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Lisinopril; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes	1997
Mibefradil in the treatment of systemic hypertension: comparative studies with other calcium antagonists. The American journal of cardiology, 1997, Aug-21, Volume: 80, Issue:4B Topics: Adult; Aged; Amlodipine; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Edema; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Leg; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes	1997
Safety of mibefradil, a new once-a-day, selective T-type calcium channel antagonist. The American journal of cardiology, 1997, Aug-21, Volume: 80, Issue:4B Topics: Aged; Amlodipine; Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Chronic Disease; Drug Administration Schedule; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Hypertension; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes	1997
Differential properties of mibefradil in hypertension and angina. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1997, Volume: 15, Issue:5 Topics: Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Heart Rate; Humans; Hypertension; Mibefradil; Nifedipine; Tetrahydronaphthalenes	1997
A comparison of the safety and efficacy of mibefradil and nifedipine SR in patients with renal disease and hypertension. Clinical nephrology, 1998, Volume: 49, Issue:3 Topics: Adult; Aged; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes	1998
Steady-state trough plasma mibefradil concentrations and correlation to blood pressure response in hypertensive patients with chronic renal disease. International journal of clinical pharmacology research, 1998, Volume: 18, Issue:3 Topics: Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypertension; Kidney Failure, Chronic; Linear Models; Mibefradil; Nifedipine; Tetrahydronaphthalenes	1998
Comparative effects of mibefradil and nifedipine gastrointestinal transport system on autonomic function in patients with mild to moderate essential hypertension. Journal of hypertension, 2001, Volume: 19, Issue:2 Topics: Autonomic Nervous System; Calcium Channel Blockers; Double-Blind Method; Electrocardiography; Female; Hemodynamics; Humans; Hypertension; Male; Mibefradil; Middle Aged; Nifedipine; Norepinephrine; Pressoreceptors; Prospective Studies	2001
Comparison of sympathetic modulation induced by single oral doses of mibefradil, amlodipine, and nifedipine in healthy volunteers. Clinical pharmacology and therapeutics, 2001, Volume: 69, Issue:3 Topics: Administration, Oral; Adult; Aldosterone; Amlodipine; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Electrocardiography; Epinephrine; Hemodynamics; Humans; Male; Mibefradil; Nifedipine; Sympathetic Nervous System	2001

Other Studies

67 other study(ies) available for nifedipine and mibefradil

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4 Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity	2004
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18 Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently. Chemical biology & drug design, 2016, Volume: 88, Issue:6 Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain	2016
Hemodynamic profile of Ro 40-5967 in conscious rats: comparison with diltiazem, verapamil, and amlodipine. Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 10 Topics: Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Hemodynamics; Male; Mibefradil; Nifedipine; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Verapamil	1991
[Inhibition of induced contraction in the isolated rat mesenteric vascular bed by Ro 40-5967, a novel calcium antagonist]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1995, Volume: 105, Issue:3 Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Electric Stimulation; Endothelins; In Vitro Techniques; Male; Mesenteric Arteries; Mibefradil; Nifedipine; Norepinephrine; Rats; Rats, Wistar; Receptors, Endothelin; Tetrahydronaphthalenes; Vasoconstriction; Vasodilator Agents	1995
Effects of the novel T-type calcium channel antagonist mibefradil on human myocardial contractility in comparison with nifedipine and verapamil. Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:5 Topics: Benzimidazoles; Calcium Channel Blockers; Electric Stimulation; Heart Ventricles; Humans; In Vitro Techniques; Mibefradil; Myocardial Contraction; Nifedipine; Papillary Muscles; Tetrahydronaphthalenes; Verapamil	1997
[Introducing mibefradil--a new T-calcium channel blocker]. Der Internist, 1997, Volume: 38, Issue:12 Suppl M Topics: Antihypertensive Agents; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Mibefradil; Nifedipine; Tetrahydronaphthalenes	1997
Different effects of calcium antagonists on fluid filtration of large arteries and albumin permeability in spontaneously hypertensive rats. Journal of hypertension, 1998, Volume: 16, Issue:3 Topics: Amlodipine; Animals; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Capillary Permeability; Carotid Arteries; Edema; Heart Rate; Hemodynamics; Hypertension; Male; Mibefradil; Nifedipine; Rats; Rats, Inbred SHR; Serum Albumin; Tetrahydronaphthalenes	1998
Potent vasodilatory with minor cardiodepressant actions of mibefradil in human cardiac tissue. British journal of pharmacology, 1998, Volume: 125, Issue:1 Topics: Adult; Aged; Arteries; Benzimidazoles; Calcium; Calcium Channel Blockers; Diltiazem; Fluorescent Dyes; Fura-2; Heart; Humans; Mibefradil; Middle Aged; Myocardium; Nifedipine; Tetrahydronaphthalenes; Vasodilator Agents	1998
Proliferation of human peripheral blood mononuclear cells during calcium channel blockade. American journal of hypertension, 1998, Volume: 11, Issue:12 Topics: Adult; Benzimidazoles; Calcium Channel Blockers; Gallic Acid; Humans; Lymphocyte Activation; Male; Mibefradil; Nifedipine; Sulfonamides; Tetrahydronaphthalenes; Time Factors	1998
Mibefradil-induced inhibition of proliferation of human peripheral blood mononuclear cells. Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Benzimidazoles; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Division; Gallic Acid; Humans; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Mibefradil; Nifedipine; Receptors, Interleukin-2; Tetrahydronaphthalenes; Time Factors	1999
Proliferation of human peripheral blood mononuclear cells during calcium entry blockade. Role of protein kinase C. Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:4 Topics: Adult; Benzimidazoles; Calcium Channel Blockers; Cell Division; Concanavalin A; DNA; Dose-Response Relationship, Drug; Humans; L-Lactate Dehydrogenase; Leucine; Leukocytes, Mononuclear; Male; Mibefradil; Nifedipine; Protein Kinase C; Pyrimidine Nucleosides; Tetradecanoylphorbol Acetate; Tetrahydronaphthalenes; Thymidine; Uridine	1999
Calcium currents in hair cells isolated from semicircular canals of the frog. Biophysical journal, 2000, Volume: 78, Issue:3 Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, R-Type; Hair Cells, Vestibular; In Vitro Techniques; Kinetics; Membrane Potentials; Mibefradil; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Rana esculenta; Semicircular Canals; Video Recording	2000
Gonadotropin-releasing hormone-stimulated sperm binding to the human zona is mediated by a calcium influx. Biology of reproduction, 2000, Volume: 63, Issue:2 Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Egtazic Acid; Female; Gonadotropin-Releasing Hormone; Humans; Male; Mibefradil; Nifedipine; Pimozide; Sperm-Ovum Interactions; Spermatozoa; Verapamil; Zona Pellucida	2000
Mibefradil, an I(Ca,T) blocker, effectively blocks I(Ca,L) in rabbit sinus node cells. European journal of pharmacology, 2000, Jul-28, Volume: 401, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Female; Mibefradil; Nifedipine; Rabbits; Sinoatrial Node	2000
Acrosome reaction of human spermatozoa is mainly mediated by alpha1H T-type calcium channels. Molecular human reproduction, 2000, Volume: 6, Issue:10 Topics: Acrosome Reaction; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Cattle; Dose-Response Relationship, Drug; Humans; Male; Mannose; Mibefradil; Nickel; Nifedipine; Protein Isoforms; Protein Subunits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serum Albumin, Bovine; Spermatozoa; Testis	2000
Influence of T-type Ca2+ (mibefradil) and Cl- (indanyloxyacetic acid 94) channel antagonists on alpha1-adrenoceptor mediated contractions in rat aorta. Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:9 Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Calcium Channel Blockers; Calcium Channels, T-Type; Chloride Channels; Diuretics; Dose-Response Relationship, Drug; Glycolates; Imidazoles; Male; Mibefradil; Nifedipine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Vasoconstriction	2000
Effects of mibefradil and nifedipine on arteriolar myogenic responsiveness and intracellular Ca(2+). British journal of pharmacology, 2000, Volume: 131, Issue:6 Topics: Animals; Arterioles; Calcium; Calcium Channel Blockers; Male; Membrane Potentials; Mibefradil; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Potassium; Rats; Rats, Sprague-Dawley	2000
Selectivity of blocking of low- versus high-voltage activated calcium currents by the dihydropyridine derivatives Bay E5759 and Bay A4339 in neuroblastoma--glioma NG 108-15 cells. Pharmacological research, 2001, Volume: 44, Issue:2 Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Electrophysiology; Hybrid Cells; Mibefradil; Mice; Nifedipine; Nisoldipine; Rats; Tumor Cells, Cultured	2001
Divergent natriuretic action of calcium channel antagonists in mongrel dogs: renal haemodynamics as a determinant of natriuresis. Clinical science (London, England : 1979), 2001, Volume: 101, Issue:4 Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Male; Mibefradil; Natriuresis; Nifedipine; Nitric Oxide; Nitrophenols; Organophosphorus Compounds; Prostaglandins; Renal Circulation	2001
Effect of T-type selective calcium antagonist on renal microcirculation: studies in the isolated perfused hydronephrotic kidney. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3 Topics: Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Hydronephrosis; In Vitro Techniques; Kidney; Male; Mibefradil; Nifedipine; Norepinephrine; Phentolamine; Rats; Rats, Wistar; Renal Artery; Renal Circulation; Time Factors; Vasoconstriction; Vasoconstrictor Agents	2001
Divergent renal vasodilator action of L- and T-type calcium antagonists in vivo. Journal of hypertension, 2001, Volume: 19, Issue:11 Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Dogs; Hemodynamics; Mibefradil; Microcirculation; Nifedipine; Nitrophenols; Organophosphorus Compounds; Renal Circulation; Vasodilation	2001
Effect of nitric oxide synthase inhibitor N(omega) nitro-L-arginine methyl ester on relaxant responses to calcium channel antagonists in isolated aortic rings from Dahl normotensive and hypertensive rats. Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:3 Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Diltiazem; Enzyme Inhibitors; Female; Hypertension; Imidazoles; In Vitro Techniques; Mibefradil; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase; Potassium Chloride; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Vasoconstrictor Agents; Vasodilation	2002
Effects of mibefradil on uterine contractility. European journal of pharmacology, 2002, Nov-22, Volume: 455, Issue:1 Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Drug Interactions; Female; Mibefradil; Nifedipine; Oxytocin; Pregnancy; Rats; Rats, Wistar; Uterine Contraction	2002
Characterization of T-type calcium current and its contribution to electrical activity in rabbit urethra. American journal of physiology. Cell physiology, 2004, Volume: 286, Issue:5 Topics: Action Potentials; Animals; Barium; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Electric Conductivity; Female; In Vitro Techniques; Male; Mibefradil; Models, Biological; Nickel; Nifedipine; Patch-Clamp Techniques; Rabbits; Urethra	2004
Depolarization-induced calcium influx in rat mesenteric small arterioles is mediated exclusively via mibefradil-sensitive calcium channels. British journal of pharmacology, 2004, Volume: 142, Issue:4 Topics: Animals; Arterioles; Blotting, Southern; Calcium; Calcium Channels; Denmark; Elapid Venoms; Fluorescence; Fura-2; Gene Expression; Lanthanum; Male; Membrane Potentials; Mesenteric Arteries; Mibefradil; Muscle, Smooth, Vascular; Nifedipine; omega-Agatoxin IVA; omega-Conotoxins; Phentolamine; Pimozide; Potassium Chloride; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Calcium Exchanger; Solutions; Spider Venoms; Tetrodotoxin	2004
Ca2+ flux through voltage-gated channels with flow cessation in pulmonary microvascular endothelial cells. Microcirculation (New York, N.Y. : 1994), 2004, Volume: 11, Issue:6 Topics: Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Capillaries; Cromakalim; Endothelial Cells; Endothelium, Vascular; Ion Channel Gating; Ion Transport; Lung; Membrane Potentials; Mibefradil; Nifedipine; Potassium Channel Blockers; Potassium Channels; Rats; Reverse Transcriptase Polymerase Chain Reaction; Rheology; RNA, Messenger	2004
Pacemaker potentials generated by interstitial cells of Cajal in the murine intestine. American journal of physiology. Cell physiology, 2005, Volume: 288, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Biological Clocks; Caffeine; Calcium Channel Blockers; Central Nervous System Stimulants; Electrophysiology; Glyburide; In Vitro Techniques; Intestine, Small; Membrane Potentials; Mibefradil; Mice; Mice, Inbred BALB C; Myocytes, Smooth Muscle; Nifedipine; Pinacidil; Vasodilator Agents	2005
Role of high-voltage-activated calcium channels in glucose-regulated beta-cell calcium homeostasis and insulin release. American journal of physiology. Endocrinology and metabolism, 2005, Volume: 289, Issue:5 Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line, Tumor; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mibefradil; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA	2005
Role of protein kinase C in Ca channel blocker-induced renal arteriolar dilation in spontaneously hypertensive rats--studies in the isolated perfused hydronephrotic kidney. The Keio journal of medicine, 2005, Volume: 54, Issue:2 Topics: Angiotensin II; Animals; Arterioles; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydronephrosis; Hypertension; Kidney; Male; Mibefradil; Microcirculation; Nifedipine; Perfusion; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Staurosporine; Thapsigargin; Vasodilator Agents	2005
Relaxant responses to calcium channel antagonists and potassium channel opener in human saphenous vein. Autonomic & autacoid pharmacology, 2006, Volume: 26, Issue:1 Topics: Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Membrane Potentials; Mibefradil; Muscle, Smooth, Vascular; Nifedipine; Pinacidil; Potassium Channels; Saphenous Vein; Vasodilation; Vasodilator Agents	2006
Inhibitory effects of L- and T-type calcium antagonists on contractions of human detrusor muscle. European journal of clinical pharmacology, 2006, Volume: 62, Issue:5 Topics: Adult; Aged; Analysis of Variance; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Carbachol; Diltiazem; Female; Humans; In Vitro Techniques; Male; Mibefradil; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Nimodipine; Potassium; Urinary Bladder; Verapamil	2006
Actions of mibefradil, efonidipine and nifedipine block of recombinant T- and L-type Ca channels with distinct inhibitory mechanisms. Pharmacology, 2006, Volume: 78, Issue:1 Topics: Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Humans; Mibefradil; Nifedipine; Nitrophenols; Organophosphorus Compounds; Recombinant Proteins	2006
Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus. Circulation, 2006, Sep-26, Volume: 114, Issue:13 Topics: Animals; Arachidonic Acids; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cytosol; Ductus Arteriosus; Endocannabinoids; Imidazoles; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoquinolines; Maleimides; Menthol; Mibefradil; Muscle Contraction; Nifedipine; Niflumic Acid; Oxidation-Reduction; Oxygen; Patch-Clamp Techniques; Polyunsaturated Alkamides; Potassium Channels; Protein Serine-Threonine Kinases; Rabbits; rho-Associated Kinases; Ruthenium Red; Sulfonamides; Tetraethylammonium; Thapsigargin; Thiourea	2006
The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:3 Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Edema; Femoral Artery; Hindlimb; Hypertension; Magnetic Resonance Imaging; Mibefradil; Muscle, Skeletal; Nifedipine; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; RNA, Messenger	2008
Heterogeneity of L- and T-channels in the vasculature: rationale for the efficacy of combined L- and T-blockade. Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:4 Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Humans; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Mibefradil; Microvessels; Nifedipine; Nitrophenols; Organophosphorus Compounds; Potassium Chloride; Rats; Rats, Sprague-Dawley; Subcutaneous Fat; Vasoconstriction; Verapamil	2009
Is combined L- and T-channel blockade better than L-channel blockade in therapy? Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:1 Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Drug Synergism; Humans; Hypertension; Mesenteric Arteries; Mibefradil; Microvessels; Nifedipine; Nitrophenols; Rats; Vasoconstriction; Verapamil	2009
Voltage-dependent Ca2+ currents contribute to spontaneous Ca2+ waves in rabbit corpus cavernosum myocytes. The journal of sexual medicine, 2009, Volume: 6, Issue:11 Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, T-Type; Cells, Cultured; Dose-Response Relationship, Drug; Male; Mibefradil; Microscopy, Confocal; Muscle Cells; Muscle, Smooth; Nifedipine; Penis; Rabbits; Reverse Transcriptase Polymerase Chain Reaction	2009
Comparative effects of T-type and L-type Ca(2+)-antagonists against noradrenaline-induced contractions of human vas deferens. BJU international, 2010, Volume: 106, Issue:4 Topics: Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Flunarizine; Humans; Male; Mibefradil; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Pyrroles; Vas Deferens	2010
Voltage-gated divalent currents in descending vasa recta pericytes. American journal of physiology. Renal physiology, 2010, Volume: 299, Issue:4 Topics: Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Kidney Medulla; Mibefradil; Models, Animal; Nickel; Nifedipine; omega-Agatoxin IVA; Patch-Clamp Techniques; Pericytes; Pyrroles; Rats	2010
Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature. Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Calcium Channels, T-Type; Female; Gene Expression; Humans; Immunohistochemistry; In Vitro Techniques; Kidney; Male; Mibefradil; Mice; Mice, Inbred C57BL; Middle Aged; Muscle, Smooth, Vascular; Nifedipine; omega-Agatoxin IVA; Renal Artery; Reverse Transcriptase Polymerase Chain Reaction; Vasoconstriction	2011
Closure of multiple types of K+ channels is necessary to induce changes in renal vascular resistance in vivo in rats. Pflugers Archiv : European journal of physiology, 2011, Volume: 462, Issue:5 Topics: Animals; Arterioles; Benzimidazoles; Calcium Channels; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Mibefradil; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Nifedipine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Renal Circulation; Vascular Resistance; Vasoconstriction	2011
T-type Ca²⁺ signalling downregulates MEK1/2 phosphorylation and cross-talk with the RAAS transcriptional response in cardiac myocytes. Journal of molecular and cellular cardiology, 2012, Volume: 53, Issue:2 Topics: Animals; Calcium Signaling; Flunarizine; Fluoxetine; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mibefradil; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Nifedipine; Phosphorylation; Rats; Rats, Wistar; Receptors, Glucocorticoid; Renin-Angiotensin System; Spironolactone	2012
[Impact of calcium channel antagonists for estrogen action on the endometrial carcinoma HEC-1A cells]. Zhonghua fu chan ke za zhi, 2012, Volume: 47, Issue:3 Topics: Apoptosis; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Mibefradil; Nifedipine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors	2012
Ca²⁺-dependent ion channels underlying spontaneous activity in insect circadian pacemaker neurons. The European journal of neuroscience, 2012, Volume: 36, Issue:8 Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Circadian Clocks; Cockroaches; Cyclic Nucleotide-Gated Cation Channels; Insect Proteins; Large-Conductance Calcium-Activated Potassium Channels; Male; Mibefradil; Neurons; Nifedipine; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Small-Conductance Calcium-Activated Potassium Channels; Sodium Channel Blockers; Tetrodotoxin; Voltage-Gated Sodium Channels	2012
The temporal characteristics of Ca2+ entry through L-type and T-type Ca2+ channels shape exocytosis efficiency in chick auditory hair cells during development. Journal of neurophysiology, 2012, Volume: 108, Issue:11 Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Chick Embryo; Cochlea; Exocytosis; Hair Cells, Auditory; Mibefradil; Neurogenesis; Nifedipine; Synaptic Transmission; Synaptic Vesicles	2012
Role of low voltage activated calcium channels in neuritogenesis and active migration of embryonic neural progenitor cells. Stem cells and development, 2013, Apr-15, Volume: 22, Issue:8 Topics: Animals; Barium; Benzimidazoles; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Differentiation; Cell Movement; Cells, Cultured; Cyclopropanes; Embryonic Stem Cells; Fura-2; Membrane Potentials; Mibefradil; Mice; Microscopy, Confocal; Naphthalenes; Neural Stem Cells; Neurites; Neurons; Nifedipine; Patch-Clamp Techniques; Time-Lapse Imaging	2013
Novel cognitive enhancer ST101 enhances acetylcholine release in mouse dorsal hippocampus through T-type voltage-gated calcium channel stimulation. Journal of pharmacological sciences, 2013, Volume: 121, Issue:3 Topics: Acetylcholine; Animals; Calcium Channels, T-Type; Cognition; Hippocampus; Indans; Injections, Intraperitoneal; Male; Memory; Mibefradil; Mice; Nifedipine; Spiro Compounds; Stimulation, Chemical	2013
T- and L-type voltage-gated calcium channels: their role in diabetic bladder dysfunction. Neurourology and urodynamics, 2014, Volume: 33, Issue:1 Topics: Acetylcholine; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Proliferation; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Male; Mibefradil; Mice; Mice, Inbred C57BL; Muscle Contraction; Myocytes, Smooth Muscle; Nifedipine; RNA, Messenger; Urinary Bladder; Urinary Bladder Diseases	2014
Distinct roles of L- and T-type voltage-dependent Ca2+ channels in regulation of lymphatic vessel contractile activity. The Journal of physiology, 2014, Dec-15, Volume: 592, Issue:24 Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Diltiazem; Lymphatic Vessels; Male; Membrane Potentials; Mibefradil; Muscle Contraction; Nickel; Nifedipine; Rats; Rats, Sprague-Dawley	2014
Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes. The international journal of biochemistry & cell biology, 2015, Volume: 68 Topics: Animals; Animals, Newborn; Autophagy; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Proliferation; Cell Survival; Endoplasmic Reticulum Stress; Gene Expression Regulation; Heart Ventricles; Heat-Shock Proteins; Macrolides; Mibefradil; Microtubule-Associated Proteins; Myocytes, Cardiac; Nifedipine; Rats; Sequestosome-1 Protein; Signal Transduction; Thapsigargin; Unfolded Protein Response	2015
Characterisation of Development and Electrophysiological Mechanisms Underlying Rhythmicity of the Avian Lymph Heart. PloS one, 2016, Volume: 11, Issue:12 Topics: Action Potentials; Animals; Biological Clocks; Calcium Channels, L-Type; Chick Embryo; Electrophysiology; Homeodomain Proteins; In Situ Hybridization; Lymphatic System; Mibefradil; Microelectrodes; Nifedipine; Tetrodotoxin	2016
Properties of synchronous spontaneous Ca Pflugers Archiv : European journal of physiology, 2017, Volume: 469, Issue:9 Topics: Animals; Arterioles; Calcium; Calcium Channel Blockers; Calcium Signaling; Chloride Channels; Male; Membrane Potentials; Mibefradil; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; Pericytes; Rats; Rats, Wistar; Rectum; Venules	2017
L-selectin activation regulates Rho GTPase activity via Ca Biochemical and biophysical research communications, 2020, 05-14, Volume: 525, Issue:4 Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; L-Selectin; Ligands; Male; Mibefradil; Nifedipine; Optical Imaging; rac1 GTP-Binding Protein; Rats; rho GTP-Binding Proteins; Sertoli Cells; Signal Transduction; Spermatogenesis; Spermatozoa	2020
Deletion of Notch3 Impairs Contractility of Renal Resistance Vessels Due to Deficient Ca International journal of molecular sciences, 2022, Dec-16, Volume: 23, Issue:24 Topics: Angiotensin II; Animals; Arterioles; Calcium; Calcium Channel Blockers; Gene Deletion; Kidney; Mibefradil; Mice; Mice, Knockout; Nifedipine; Receptor, Notch3; Vascular Resistance	2022