nifedipine has been researched along with metoprolol in 154 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 69 (44.81) | 18.7374 |
| 1990's | 47 (30.52) | 18.2507 |
| 2000's | 17 (11.04) | 29.6817 |
| 2010's | 20 (12.99) | 24.3611 |
| 2020's | 1 (0.65) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Beaumont, K; Di, L; Maurer, TS; Smith, DA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Beeley, L; Talbot, J | 1 |
| Lederballe Pedersen, O; Mikkelsen, E | 1 |
| Ekelund, LG; Orö, L | 1 |
| Appenheimer, M; Düsing, R; Graack, GH; Ko, YD; Sachinidis, A; Vetter, H; Wieczorek, AJ | 1 |
| Blake, P; Lewis, JA | 1 |
| Graack, GK; Ko, Y; Sachinidis, A; Vetter, H; Wieczorek, AJ | 1 |
| Adamczyk, W; Bielski, K; Elikowski, W; Pawlak, B | 1 |
| Fransson, L; Koch, G | 2 |
| Littler, WA | 1 |
| Duncker, DJ; Gho, BC; McFalls, EO; Sassen, LM; Verdouw, PD | 1 |
| Albertini, A; Giudici, V; Mannarini, A; Radice, M | 1 |
| Proli, J | 1 |
| Egstrup, K | 2 |
| Babb, JD; Baim, DS; Braunwald, E; Chesebro, JH; Frederick, M; Gore, JM; Passamani, ER; Roberts, R; Rogers, WJ; Williams, DO | 1 |
| Rao, MR; Wang, YQ | 1 |
| Bargossi, A; Branzi, A; Degli Esposti, D; Fallani, F; Magnani, B; Melandri, G; Motta, R; Piazzi, S; Tartagni, F | 1 |
| Ardissino, D; Egstrup, K; Feruglio, GA; Giordano, MP; Marraccini, P; Roncarolo, P; Rosenfeld, M; Savonitto, S; Slavich, G; Wahlqvist, I | 1 |
| Diener, HC; Gerber, WD; Niederberger, U; Scholz, E | 1 |
| Strauer, BE | 1 |
| Behr, U; Franz, IW; Ketelhut, R; Tönnesmann, U | 3 |
| Guliev, AB; Lupanov, VP; Sidorenko, BA | 1 |
| Bekheit, S; Craelius, W; el-Sakr, A; el-Sherif, N; Rasheed, Q; Tangella, M | 1 |
| Pun, CO; Woo, KS | 1 |
| Myers, MG; Raemsch, KD | 1 |
| Alberti, D; Antivalle, M; Lattuada, S; Libretti, A; Montanari, M; Rindi, M | 1 |
| Lubsen, J; Tijssen, JG | 4 |
| Bestetti, RB; Finzi, LA; Pinto, LZ; Secches, AL | 1 |
| Katsenovich, RA; Kostko, SZ | 1 |
| Metelitsa, VI | 1 |
| Bille, A; Dichgans, J; Diener, HC; Gerber, WD; Jäck, A; Niederberger, U; Scholz, E | 1 |
| Koch, G | 1 |
| Yusuf, S | 1 |
| de Feijter, PJ; Hugenholtz, PG; Lubsen, J; Simoons, ML; Tijssen, JG | 1 |
| Ichihara, T; Kageyama, M; Kawazoe, S; Matsumura, Y; Morimoto, S; Shinyama, H | 1 |
| Arstila, M; Bae, EA; Härkönen, R; Keyriläinen, O; Rytkönen, U; Schjelderup-Mathiesen, PM; Uusitalo, A; Wendelin, H | 1 |
| Cocco, C; Franceschini, L; Menegatti, G; Nidasio, GP; Rizzotti, P; Vassanelli, C | 1 |
| Lubsen, J; Tijssen, JG; van Es, GA; van Gilst, WH | 1 |
| Ciancio, SG | 1 |
| Baumann, J; Ebner, F; Weihrauch, T | 1 |
| Boström, PA | 1 |
| Burdick, JF; Keown, PA; Racusen, LC; Solez, K; Vaughn, WK | 1 |
| Kerkkamp, HJ; Lie, KI; Lubsen, J; Tijssen, JG | 1 |
| de Beijer, JM; de Feijter, PJ; Kerkkamp, HJ; Lubsen, J; Tijssen, JG; Viersma, JW | 1 |
| Bom, N; Kerkkamp, HJ; Lie, KI; Lubsen, JC; Reiber, JH; Simoons, ML; van der Wall, EE; van Rijk, PP | 2 |
| Friberg, P; Nordlander, M | 1 |
| Andreoli, C; Cioni, G; Mattioli, G | 1 |
| Frais, MA; Midtbo, KA; Müller, P; Reynolds, G; Silke, B; Taylor, SH; Verma, SP | 1 |
| Dahlöf, C; Franco-Cereceda, A; Lundberg, JM | 1 |
| Barbour, MP; Forret, EA; Hill, TW; Lawrie, TD; Lorimer, AR; McAlpine, HM; Rae, AP; Simpson, IA | 1 |
| Bom, N; Kerkkamp, HJ; Lie, KI; Lubsen, J; Reiber, JH; Roos, JP; Simoons, ML; van der Wall, EE; van Rijk, PP | 1 |
| Burkart, F; Pfisterer, M | 1 |
| Antman, E; Ganz, P; Holman, BL; Koslowski, J; Nesto, RW; White, HD; Wynne, J | 1 |
| Choong, CY; Harris, PJ; Kelly, DT; Roubin, GS; Shen, WF; Tokuyasu, Y | 1 |
| Clement, DL; De Pue, NY | 1 |
| Bengtsson, B; Edgar, B; Raner, S; Rönn, O | 1 |
| Been, M; de Vane, PJ; Hillis, WS; Hornung, RS; Jamieson, RR; Jones, CR; Rae, AP | 1 |
| Frais, MA; Jackson, N; Reynolds, G; Silke, B; Taylor, SH; Verma, SP | 1 |
| Bellens, R; Degre, S; Degreve, M; Fitzsimons, TJ; Gangji, D; Herchuelz, A; Juvent, M; Niset, G; Poortmans, J; Wathieu, M | 1 |
| Janisch, HD; Kirch, W; Ohnhaus, EE; Rämsch, K | 1 |
| Hallbäck-Nordlander, MI; Lundin, SA | 1 |
| Hugenholtz, PG; Lubsen, J | 1 |
| Emanuelsson, H; Herlitz, J; Hjalmarson, A; Holmberg, S; Waagstein, F; Waldenström, A; Waldenström, J | 1 |
| Burkart, F; Glaus, L; Pfisterer, M | 1 |
| Hess, DS; Scheinman, MM | 1 |
| Hugenholtz, PG; Michels, R; Serruys, PW; Simoons, ML | 1 |
| Burkart, F; Fridrich, R; Pfisterer, M | 1 |
| Jack, DB; Kendall, MJ; Laugher, SJ; Lobo, J; Rolf Smith, S | 1 |
| Downey, JM; Hearse, DJ; Yellon, DM | 1 |
| Ahuja, RC; Forsyth, D; Hussain, M; Nelson, GI; Silke, B; Taylor, SH | 1 |
| Ekelund, C; Ekelund, LG; Rössner, S | 1 |
| Efsen, F; Sandøe, E; Vilhelmsen, R | 1 |
| Hagemeijer, F; Santoso, T; van Mechelen, R | 1 |
| Jenkins, RM; Nagle, RE | 1 |
| Baadsgaard, O; Schmidt, JF | 1 |
| Eggertsen, R; Hansson, L | 1 |
| Binder, TM; Podesser, BK; Schwarzacher, S; Seitelberger, R; Wolner, E; Zwoelfer, W | 1 |
| Górecki, A; Ignatowska-Switalska, H; Januszewicz, A; Kochanowski, J; Lapiński, M; Opolski, G; Stolarz, P; Słomka, K; Wocial, B | 1 |
| Li, QP; Rao, MR | 1 |
| Ardissino, D; Bae, EA; Egstrup, K; Marraccini, P; Merlini, PA; Omland, T; Rasmussen, K; Savonitto, S; Schjelderup-Mathiesen, PM; Wahlqvist, I | 1 |
| Binder, T; Huber, S; Peschl, F; Podesser, B; Schwarzacher, S; Seitelberger, R; Spatt, J; Wolner, E; Zwölfer, W | 1 |
| Bergstrand, R; Eriksson, M; Lidman, K; Nyberg, G; Olofsson, B | 1 |
| Alberti, KG; Boon, NA; MacGregor, IR; Perrie, AM; Riemersma, RA; Stenhouse, F; Wright, RA | 1 |
| Spence, JD | 1 |
| Motokawa, K; Naito, H; Ohashi, N; Sato, S; Takahashi, H | 1 |
| Binder, TM; Huber, S; Peschl, F; Podesser, B; Schwarzacher, S; Seitelberger, R; Spatt, J; Zwölfer, W | 1 |
| Brachmann, J; Dickhaus, H; Kirchner, U; Kübler, W; Metze, C; Schweizer, MW; Walter-Sack, I | 1 |
| Andersen, PE; Egstrup, K | 1 |
| Becker, A; Böhler, J; Keller, E; Reetze-Bonorden, P; Schollmeyer, P; Woitas, R | 1 |
| Haczyński, J; Jołda-Mydłowska, B; Spring, A; Witkowska, M | 1 |
| Zanchetti, A | 1 |
| Ardissiono, D; Bae, EA; Egstrup, K; Marraccini, P; Merlini, PA; Omland, T; Rasmussen, K; Rehnqvist, N; Savonitto, S; Schjelderup-Mathiesen, PM; Wahlqvist, I | 1 |
| Asokumar, B; Boylen, P; Cheng, DC; Jiang, MT; Sandler, A | 1 |
| Bertocchi, F; Carotenuto, A; Cudemo, G; de Divitiis, M; de Divitiis, O; Di Somma, S; Napodano, M; Petitto, M | 1 |
| Lai, KN; Lam, WK; Li, KT; Lui, SF; Nicholls, MG; Wong, KC; Woo, KS | 1 |
| Bhatt, AD; Dadkar, VN; Kapadia, NM; Karnik, ND; Khokhani, RC; Trivedi, TH; Vaidya, AB | 1 |
| Bossi, M; Tiberti, G | 1 |
| Irlbeck, M; Iwai, T; Zimmer, HG | 1 |
| Behnke, B; Gebhardt, A; Naegele, H; Strohbeck, M | 1 |
| Böhm, M; Bohnemeier, H; Horkay, F; Juhász-Nagy, A; Orzechowski, HD; Paul, M; Pinto, YM; Tóth, M | 1 |
| Fernandes, AC; Filipe, PM; Manso, CF; Silva, JM | 1 |
| Chen, S; Liu, G; Yang, T | 1 |
| Harano, Y; Kodama, K; Koyama, Y; Suzuki, M | 1 |
| Iida, H; Iwasawa, K; Jo, T; Ma, J; Nagai, R; Nakajima, T; Omata, M | 1 |
| Andreeva, GF; Dmitrieva, NA; Gorbunov, VM; Isaĭkina, OIu; Martsevich, SIu | 1 |
| Alexopoulos, D; Chiladakis, JA | 1 |
| Weber, MA | 1 |
| Fomin, VV; Kozlovskaia, NL; Moiseev, SV; Osipenko, VI; Safonov, VV; Tironishvili, OI | 1 |
| Arisoy, N; Bariş, S; Calişkan, S; Cantaşdemir, M; Civilibal, M; Doğan, D; Kasapçopur, O; Numan, F; Sever, L | 1 |
| Bhaskar, K; Kumaravelrajan, R; Narayanan, N; Suba, V | 1 |
| Guo, WZ; Ji, H; Li, D; Lu, CL; Yan, ZH | 1 |
| Cedillo, FD; Cervera, EG; Cordoba, J; Quijano, K; Ramos, ML; Valverde, LF | 1 |
| Kumaravelrajan, R; Narayanan, N; Suba, V | 1 |
| Díaz-Cedillo, F; Figueroa-Valverde, L; García-Cervera, E; López-Ramos, M; Martinez-Camacho, R; Pool Gómez, E; Rosas-Nexticapa, M | 1 |
| Eren Cevik, S; Guneysel, O; Tasyurek, T | 1 |
| Dahlgren, D; Lennernäs, H; Roos, C; Sjögren, E | 1 |
| Kotegawa, T; Koya, Y; Machi, Y; Namiki, N; Shobu, Y; Uchida, S | 1 |
| Coboeken, K; Dallmann, A; Eissing, T; Hempel, G; Ince, I | 1 |
| Huang, H; Huang, Y; Lu, X; Wang, Z; Wu, X; Xiao, J; Zhang, L | 1 |
5 review(s) available for nifedipine and metoprolol
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Nifedipine and metoprolol in suspected unstable angina. Unstable angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Artery Disease; Humans; Metoprolol; Netherlands; Nifedipine; Nitrates | 1987 |
New antiarrhythmic drugs.
Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Blood Circulation; Bradycardia; Diltiazem; Half-Life; Humans; Hypertension; Lidocaine; Metoprolol; Nadolol; Nifedipine; Propanolamines; Propranolol; Tocainide; Verapamil | 1983 |
The role of the new beta-blockers in treating cardiovascular disease.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Benzopyrans; Cardiovascular Diseases; Clinical Trials as Topic; Enalapril; Ethanolamines; Female; Heart Failure; Hemodynamics; Humans; Hypertension; Labetalol; Losartan; Male; Metoprolol; Middle Aged; Nebivolol; Nifedipine; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sympathomimetics | 2005 |
67 trial(s) available for nifedipine and metoprolol
| Article | Year |
|---|---|
Antianginal efficiency of nifedipine with and without a beta-blocker, studied with exercise test. A double-blind, randomized subacute study.
Topics: Aged; Alprenolol; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Placebos; Practolol; Pyridines | 1979 |
Comparison of felodipine with nifedipine as additions to metoprolol in the treatment of hypertension. U.K. Multicentre Hospital Group.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Felodipine; Heart Rate; Humans; Hypertension; Metoprolol; Middle Aged; Nifedipine; Randomized Controlled Trials as Topic | 1990 |
Attenuation of circadian variation by combined antianginal therapy with suppression of morning and evening increases in transient myocardial ischemia.
Topics: Angina Pectoris; Circadian Rhythm; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Electrocardiography, Ambulatory; Humans; Metoprolol; Middle Aged; Nifedipine | 1991 |
Selective versus routine predischarge coronary arteriography after therapy with recombinant tissue-type plasminogen activator, heparin and aspirin for acute myocardial infarction. TIMI II Investigators.
Topics: Aged; Aspirin; Coronary Angiography; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Exercise Test; Female; Follow-Up Studies; Heparin; Humans; Length of Stay; Male; Metoprolol; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Nifedipine; Prospective Studies; Radionuclide Ventriculography; Recurrence; Survival Rate; Thrombolytic Therapy; Tissue Plasminogen Activator | 1991 |
Transient myocardial ischemia during daily life in rest and exertional angina pectoris and comparison of effectiveness of metoprolol versus nifedipine.
Topics: Angina Pectoris; Circadian Rhythm; Coronary Angiography; Coronary Disease; Double-Blind Method; Electrocardiography, Ambulatory; Female; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Physical Exertion; Surveys and Questionnaires | 1991 |
Responders and non-responders to metoprolol, propranolol and nifedipine treatment in migraine prophylaxis: a dose-range study based on time-series analysis.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Migraine Disorders; Nifedipine; Propranolol; Statistics as Topic; Time Factors | 1991 |
[Regression of left ventricular hypertrophy in hypertensive patients under long-term therapy with antihypertensive agents].
Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Female; Gallopamil; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Time Factors | 1990 |
[The use of metoprolol with calcium antagonists of different mechanisms of action (diltiazem and nifedipine) in patients with stenocardia of effort].
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Diltiazem; Drug Therapy, Combination; Hemodynamics; Humans; Metoprolol; Middle Aged; Nifedipine; Physical Endurance; Physical Exertion; Single-Blind Method | 1990 |
Use of heart rate spectral analysis to study the effects of calcium channel blockers on sympathetic activity after myocardial infarction.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Nifedipine; Sympathetic Nervous System | 1990 |
Long-acting nifedipine versus metoprolol as monotherapy for essential hypertension. A randomized, controlled crossover study.
Topics: Adult; Aged; Delayed-Action Preparations; Humans; Hypertension; Metoprolol; Middle Aged; Nifedipine; Randomized Controlled Trials as Topic | 1990 |
Comparative pharmacokinetics and antihypertensive effects of the nifedipine tablet and capsule.
Topics: Aged; Blood Pressure; Capsules; Double-Blind Method; Half-Life; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Random Allocation; Tablets | 1987 |
Slow-release metoprolol and nifedipine in essential hypertension: 24 hour noninvasive ambulatory blood pressure monitoring.
Topics: Adult; Ambulatory Care; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Monitoring, Physiologic; Nifedipine; Random Allocation | 1987 |
Early treatment of unstable angina with nifedipine and metoprolol--the HINT trial.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Random Allocation; Risk Factors | 1988 |
Nifedipine and metoprolol in unstable angina: findings from the Holland Interuniversity Nifedipine/Metoprolol Trial (HINT).
Topics: Aged; Angina Pectoris; Angina, Unstable; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Netherlands; Nifedipine; Randomized Controlled Trials as Topic | 1987 |
[Regression of left heart hypertrophy in hypertensive patients as a result of antihypertensive therapy].
Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiac Output; Cardiac Volume; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Enalapril; Female; Gallopamil; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine | 1989 |
[Ways of individualizing use of anti-anginal preparations].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Clinical Trials as Topic; Dose-Response Relationship, Drug; Exercise Test; Humans; Isosorbide Dinitrate; Metoprolol; Nifedipine; Placebos; Propranolol; Vasodilator Agents | 1989 |
Central effects of drugs used in migraine prophylaxis evaluated by visual evoked potentials.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Evoked Potentials, Visual; Female; Humans; Male; Metoprolol; Migraine Disorders; Nifedipine; Propranolol; Random Allocation; Reaction Time | 1989 |
Hemodynamic and adrenergic effects of combined alpha/beta-receptor blockade versus combined beta-receptor and slow channel calcium blockade in patients with ischemic heart disease.
Topics: Adult; Aged; Blood Pressure; Coronary Disease; Drug Therapy, Combination; Exercise Test; Hemodynamics; Humans; Labetalol; Male; Metoprolol; Middle Aged; Nifedipine; Random Allocation | 1989 |
Differential hemodynamic effects of beta-adrenoceptor blockers, Ca antagonists and combined alpha-beta-receptor blockade in ischemic heart disease.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Hemodynamics; Humans; Labetalol; Metoprolol; Middle Aged; Nifedipine; Vascular Resistance | 1986 |
Early treatment of unstable angina in the coronary care unit: a randomised, double blind, placebo controlled comparison of recurrent ischaemia in patients treated with nifedipine or metoprolol or both. Report of The Holland Interuniversity Nifedipine/Meto
Topics: Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Care Units; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Nifedipine; Prognosis; Random Allocation; Recurrence | 1986 |
Efficacy of nifedipine and metoprolol in the early treatment of unstable angina in the coronary care unit: findings from the Holland Interuniversity Nifedipine/metoprolol Trial (HINT).
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Care Units; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Netherlands; Nifedipine; Random Allocation; Risk; Time Factors | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Unstable angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Artery Disease; Humans; Metoprolol; Netherlands; Nifedipine; Nitrates | 1987 |
Metoprolol, nifedipine, and the combination in stable effort angina pectoris.
Topics: Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Heart Function Tests; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Nitroglycerin; Physical Exertion | 1986 |
Randomized double-blind comparison of metoprolol, nifedipine, and their combination in chronic stable angina: effects on total ischemic activity and heart rate at onset of ischemia.
Topics: Angina Pectoris; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Monitoring, Physiologic; Nifedipine; Random Allocation | 1988 |
Early treatment of unstable angina in the coronary care unit: a randomised, double blind, placebo controlled comparison of recurrent ischaemia in patients treated with nifedipine or metoprolol or both.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Metoprolol; Nifedipine; Random Allocation | 1988 |
Hemodynamic effects of metoprolol and nifedipine in angina pectoris measured by isotope technique.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Nifedipine; Stroke Volume; Technetium | 1988 |
Nifedipine and metoprolol in suspected unstable angina. The Holland Interuniversity Nifedipine/Metoprolol Trial.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Metoprolol; Netherlands; Nifedipine; Random Allocation | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Principles of intervention research.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Ethics, Medical; Humans; Metoprolol; Netherlands; Nifedipine; Research Design | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Formation of the HINT cohort.
Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Electrocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Netherlands; Nifedipine; Research Design | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Treatment, observations, and outcome events.
Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Netherlands; Nifedipine; Radiography; Random Allocation; Research Design | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Data analysis.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Humans; Metoprolol; Netherlands; Nifedipine; Random Allocation; Risk Factors | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Planning and conduct.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Metoprolol; Netherlands; Nifedipine; Random Allocation; Research Design | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Progress monitoring and termination.
Topics: Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Metoprolol; Netherlands; Nifedipine; Random Allocation; Research Design | 1987 |
Effects of nifedipine on left ventricular performance in unstable angina pectoris during a follow-up of 48 hours.
Topics: Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Female; Heart; Heart Ventricles; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Radionuclide Imaging; Thallium; Time Factors | 1986 |
Influence of nifedipine on left ventricular perfusion and function in patients with unstable angina: evaluation with radionuclide techniques.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Circulation; Double-Blind Method; Female; Heart; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Radioisotopes; Radionuclide Imaging; Random Allocation; Stroke Volume; Thallium; Time Factors | 1986 |
Time sequence of anginal pain.
Topics: Adult; Aged; Angina Pectoris; Circadian Rhythm; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Nifedipine; Pain; Seasons; Time | 1986 |
A haemodynamic study of the effects of combined slow-calcium channel blockade (nisoldipine) and beta-blockade (metoprolol) in coronary heart disease.
Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Hemodynamics; Humans; Metoprolol; Middle Aged; Nifedipine; Nisoldipine; Random Allocation | 1986 |
Effects of felodipine on rest and exercise heart rate and blood pressure in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Physical Exertion; Random Allocation | 1985 |
Left ventricular performance in unstable angina: assessment with radionuclide techniques.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Angiography; Coronary Disease; Double-Blind Method; Electrocardiography; Female; Heart Ventricles; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Myocardial Infarction; Nifedipine; Radioisotopes; Radionuclide Imaging; Stroke Volume; Thallium | 1985 |
Effect of short and long term administration of amiodarone on ischaemia-induced left ventricular dysfunction. Implications for combined antianginal drug therapy.
Topics: Adult; Amiodarone; Angina Pectoris; Benzofurans; Coronary Disease; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Nitroglycerin | 1985 |
Acute haemodynamic effects of felodipine and verapamil in man, singly and with metoprolol.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Felodipine; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Nifedipine; Regional Blood Flow; Stroke Volume; Vascular Resistance; Verapamil | 1985 |
Haemodynamic analysis of the effects of nicardipine and metoprolol alone and in combination in coronary artery disease.
Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Nicardipine; Nifedipine | 1985 |
Acute myocardial ischaemia: what information can be expected in the near future from ongoing clinical trials with nifedipine?
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Electrocardiography; Humans; Metoprolol; Myocardial Infarction; Nifedipine | 1983 |
Hemodynamic and clinical findings after combined therapy with metoprolol and nifedipine in acute myocardial infarction.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Nifedipine; Random Allocation | 1984 |
Comparative effects of nitroglycerin, nifedipine and metoprolol on regional left ventricular function in patients with one-vessel coronary disease.
Topics: Adult; Aged; Cardiac Output; Coronary Disease; Coronary Vessels; Female; Heart Ventricles; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Nitroglycerin; Physical Exertion; Propanolamines; Pyridines; Stroke Volume | 1983 |
Antihypertensive effects at rest and during exercise of a calcium blocker, nifedipine, alone and in combination with metoprolol.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Physical Exertion; Propanolamines; Pyridines; Renin; Rest | 1982 |
The symptomatic and objective effects of nifedipine in combination with beta-blocker therapy in severe angina pectoris.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Nitroglycerin; Oxprenolol; Propanolamines; Pyridines | 1982 |
[Combined treatment of angina pectoris with nifedipine and metoprolol].
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Propanolamines; Pyridines | 1981 |
Effects of treatment with nifedipine and metoprolol in essential hypertension.
Topics: Adult; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Propanolamines; Pyridines | 1982 |
Comparison of perioperative myocardial protection with nifedipine versus nifedipine and metoprolol in patients undergoing elective coronary artery bypass grafting.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Artery Bypass; Creatine Kinase; Elective Surgical Procedures; Electrocardiography; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Infusions, Intravenous; Isoenzymes; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Nifedipine | 1995 |
Selection of medical treatment in stable angina pectoris: results of the International Multicenter Angina Exercise (IMAGE) Study.
Topics: Angina Pectoris; Delayed-Action Preparations; Double-Blind Method; Electrocardiography; Exercise Test; Exercise Tolerance; Female; Humans; Male; Metoprolol; Middle Aged; Multivariate Analysis; Nifedipine; Predictive Value of Tests; Prospective Studies; Surveys and Questionnaires | 1995 |
Perioperative infusion of nifedipine and metoprolol provides antiischemic and antiarrhythmic protection in patients undergoing elective aortocoronary by-pass surgery.
Topics: Arrhythmias, Cardiac; Coronary Artery Bypass; Creatine Kinase; Electrocardiography, Ambulatory; Endarterectomy; Heart Rate; Humans; Infusions, Intravenous; Intraoperative Care; Intraoperative Complications; Isoenzymes; Metoprolol; Myocardial Ischemia; Nifedipine; Time Factors | 1994 |
Aiming for steady 24-hour plasma concentrations: a comparison of two calcium antagonist and beta-blocker combinations.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Chromatography, Gas; Chromatography, Liquid; Delayed-Action Preparations; Drug Combinations; Electrocardiography; Felodipine; Humans; Male; Metoprolol; Nifedipine | 1993 |
The long-term effects of metoprolol and epanolol on tissue-type plasminogen activator and plasminogen activator inhibitor 1 in patients with ischaemic heart disease.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Benzeneacetamides; Blood Glucose; Blood Pressure; Double-Blind Method; Humans; Insulin; Lipids; Male; Metoprolol; Nifedipine; Plasminogen Activator Inhibitor 1; Propanolamines; Risk Factors; Tissue Plasminogen Activator | 1994 |
Effects of antihypertensive drugs on flow disturbances: nifedipine, captopril, and metoprolol evaluated by quantitative spectral analysis of Doppler flow patterns in patients with carotid stenosis.
Topics: Aged; Blood Pressure; Captopril; Cardiac Output; Carotid Stenosis; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Laser-Doppler Flowmetry; Male; Metoprolol; Nifedipine; Regional Blood Flow; Vascular Resistance | 1994 |
Combined perioperative infusion of nifedipine and metoprolol provides antiischemic and antiarrhythmic protection in patients undergoing elective aortocoronary bypass surgery.
Topics: Aged; Arrhythmias, Cardiac; Coronary Artery Bypass; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Hemodynamics; Humans; Infusions, Intravenous; Intraoperative Complications; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Nifedipine; Preoperative Care; Time Factors | 1993 |
Heart rate variability in time and frequency domains: effects of gallopamil, nifedipine, and metoprolol compared with placebo.
Topics: Adult; Blood Pressure; Gallopamil; Heart Rate; Humans; Male; Metoprolol; Nifedipine; Single-Blind Method; Sympathetic Nervous System | 1993 |
Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol.
Topics: Angina Pectoris; Collateral Circulation; Coronary Angiography; Coronary Circulation; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Nifedipine | 1993 |
[The effect of hypotensive drugs on left ventricular mass and diastolic function].
Topics: Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Diastole; Drug Therapy, Combination; Echocardiography, Doppler, Pulsed; Humans; Hypertension; Hypertrophy, Left Ventricular; Metoprolol; Middle Aged; Nifedipine; Remission Induction; Ventricular Function, Left | 1995 |
Addition of urapidil or metoprolol to the treatment of hypertensive non-responders to nifedipine monotherapy: efficacy and metabolic effects. Italian Urapidil Study Group.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Piperazines | 1995 |
Combination therapy with metoprolol and nifedipine versus monotherapy in patients with stable angina pectoris. Results of the International Multicenter Angina Exercise (IMAGE) Study.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Exercise Tolerance; Female; Humans; Male; Metoprolol; Middle Aged; Nifedipine | 1996 |
Treatment of hypertension associated with stable angina pectoris: favourable interaction between new metoprolol formulation (OROS) and nifedipine.
Topics: Angina Pectoris; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chronic Disease; Cross-Over Studies; Double-Blind Method; Drug Synergism; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Nitroglycerin; Regression Analysis; Vasodilator Agents | 1996 |
A comparison of the effect of enalapril and metoprolol on renal function, potassium balance, lipid profile, cardiac function, exercise tolerance and quality of life in hypertensive dialysis patients.
Topics: Adult; Anemia; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Cell Count; Blood Pressure; Electrocardiography; Enalapril; Exercise Tolerance; Female; Humans; Hypertension; Kidney Failure, Chronic; Kidney Function Tests; Lipids; Male; Metoprolol; Middle Aged; Nifedipine; Peritoneal Dialysis, Continuous Ambulatory; Potassium; Quality of Life; Renal Dialysis | 1995 |
Nifedipine, captopril, metoprolol and nifedipine with metoprolol in hypertensive crisis in non-intensive care setting.
Topics: Acute Disease; Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Captopril; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Safety; Treatment Outcome; Vasodilator Agents | 1996 |
[Effect of antihypertensive agents on plasma endothelin, nitric oxide and so on in essential hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cyclic GMP; Enalapril; Endothelins; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Nitric Oxide | 1997 |
Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Area Under Curve; Blood Glucose; Calcium Channel Blockers; Delayed-Action Preparations; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Humans; Hypertension; Insulin; Insulin Resistance; Ketones; Male; Metoprolol; Middle Aged; Nifedipine; Treatment Outcome | 2002 |
[Assessment of the efficacy and tolerance of delayed-action nifedipine as the monotherapy or in combination with metoprolol in patients with arterial hypertension].
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Delayed-Action Preparations; Drug Therapy, Combination; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine | 2003 |
83 other study(ies) available for nifedipine and metoprolol
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Volume of Distribution in Drug Design.
Topics: Drug Design; Half-Life; Pharmacokinetics | 2015 |
Beta-blocker withdrawal syndrome?
Topics: Angina Pectoris; Humans; Metoprolol; Nifedipine; Propanolamines; Substance Withdrawal Syndrome | 1979 |
Beta-blocker withdrawal syndrome.
Topics: Humans; Metoprolol; Nifedipine; Propanolamines; Propranolol; Pyridines; Substance Withdrawal Syndrome; Timolol | 1979 |
Inhibition of angiotensin II and platelet-derived growth factor-induced vascular smooth muscle cell proliferation by calcium entry blockers.
Topics: Angiotensin II; Animals; Calcium Channel Blockers; Cell Division; Cells, Cultured; Diltiazem; DNA Replication; Dose-Response Relationship, Drug; Enalaprilat; Female; Metoprolol; Muscle, Smooth, Vascular; Nifedipine; Platelet-Derived Growth Factor; Rats; Rats, Inbred WKY | 1992 |
Epanolol as a model for assessing patient preference in anti-anginal drug therapy.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Benzeneacetamides; Choice Behavior; Female; Humans; Male; Metoprolol; Middle Aged; Models, Biological; Nifedipine; Patient Compliance; Propanolamines; Quality of Life | 1992 |
Action of metoprolol, enalapril, diltiazem, verapamil, and nifedipine on cell growth of vascular smooth muscle cells.
Topics: Animals; Cell Division; Diltiazem; Enalapril; Metoprolol; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Inbred WKY; Thymidine | 1992 |
[Left coronary artery-pulmonary artery fistula. Case report].
Topics: Arterio-Arterial Fistula; Coronary Angiography; Coronary Vessels; Drug Therapy, Combination; Electrocardiography, Ambulatory; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Pulmonary Artery | 1992 |
Acute effects of combined alpha/beta-adrenoceptor blockade v combined beta-receptor and slow channel calcium blockade in ischemic heart disease complicated by hypertension. Hemodynamic and adrenergic responses.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Epinephrine; Heart Rate; Hemodynamics; Humans; Hypertension; Labetalol; Male; Metoprolol; Middle Aged; Nifedipine; Renin; Stroke Volume; Vascular Resistance | 1991 |
Effect of antiischemic therapy on coronary flow reserve and the pressure-maximal coronary flow relationship in anesthetized swine.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Benzeneacetamides; Blood Pressure; Coronary Circulation; Coronary Disease; Heart Rate; Metoprolol; Nifedipine; Propanolamines; Swine | 1991 |
Paradoxical effect of long-term treatment of nifedipine on total ischemic load in patients with stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Diltiazem; Electrocardiography, Ambulatory; Exercise Test; Female; Heart; Humans; Male; Metoprolol; Middle Aged; Nifedipine | 1992 |
Management of aortic dissection after coronary artery bypass.
Topics: Aortic Aneurysm; Aortic Dissection; Aortography; Coronary Artery Bypass; Diagnosis, Differential; Echocardiography; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Postoperative Complications; Tomography, X-Ray Computed | 1992 |
[Effect of M-nifedipine and metoprolol in combination on the hemodynamics in rabbits].
Topics: Animals; Blood Pressure; Drug Synergism; Female; Heart Rate; Hemodynamics; Isomerism; Male; Metoprolol; Nifedipine; Rabbits; Vascular Resistance | 1991 |
Myocardial metabolic and hemodynamic effects of a sustained intravenous infusion of nifedipine with and without metoprolol in patients with unstable angina.
Topics: Adult; Aged; Angina, Unstable; Coronary Circulation; Drug Therapy, Combination; Fatty Acids, Nonesterified; Female; Hemodynamics; Humans; Infusions, Intravenous; Lactates; Male; Metoprolol; Middle Aged; Myocardium; Nifedipine; Oxygen Consumption; Regression Analysis | 1991 |
Significance of coronary circulation in hypertensive heart disease for development and prevention of heart failure.
Topics: Adult; Animals; Cardiac Output, Low; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary Vessels; Felodipine; Humans; Hydralazine; Hypertension; Metoprolol; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1990 |
Impending myocardial infarction in a patient with marked left ventricular hypertrophy and normal coronary arteriogram--a case report.
Topics: Angiocardiography; Angiography; Cardiomegaly; Coronary Angiography; Echocardiography; Electrocardiography; Female; Humans; Metoprolol; Middle Aged; Myocardial Infarction; Nifedipine; Reference Values; Stroke Volume | 1989 |
[Drugs in secondary prevention of ischemic heart disease: achievements, problems and prospects].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Nadolol; Nifedipine; Nitrates; Nitroglycerin; Propranolol; Verapamil | 1989 |
The use of beta-adrenergic blocking agents, i.v. nitrates and calcium channel blocking agents following acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Humans; Infusions, Intravenous; Metoprolol; Myocardial Infarction; Nifedipine; Nitrates; Nitroglycerin; Nitroprusside; Verapamil | 1988 |
Long-term effect of antihypertensive therapy on left ventricular hypertrophy.
Topics: Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Female; Gallopamil; Humans; Hypertension; Male; Metoprolol; Nifedipine; Physical Exertion | 1987 |
Stimulatory effects of neuronally released norepinephrine on renin release in vitro.
Topics: Animals; Cations, Divalent; Denervation; In Vitro Techniques; Kidney Cortex; Kinetics; Male; Metoprolol; Neurons; Nifedipine; Norepinephrine; Potassium; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Reference Values; Renin; Sympathetic Nervous System | 1988 |
Comparison of different pharmacological interventions on enzymatic parameters during acute myocardial infarction.
Topics: Adult; Aged; Clinical Enzyme Tests; Creatine Kinase; Dipyridamole; Female; Heart; Heparin; Humans; Isoenzymes; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Nifedipine; Nitroglycerin; Streptokinase; Verapamil | 1987 |
Serum potassium values in relation to the use of diuretics in patients with unstable angina pectoris.
Topics: Angina Pectoris; Angina, Unstable; Coronary Disease; Diuretics; Female; Humans; Hypokalemia; Male; Metoprolol; Nifedipine; Potassium; Retrospective Studies; Sex Factors | 1988 |
Drugs in dentistry: Commonly prescribed medications, Part IV.
Topics: Dental Care; Drug Therapy; Humans; Metoprolol; Nifedipine; Ranitidine; Theophylline; Thyroxine | 1988 |
The influence of antihypertensive drug therapy on renal transplant function and outcome.
Topics: Antihypertensive Agents; Clonidine; Creatinine; Cyclosporins; Graft Rejection; Humans; Kidney; Kidney Transplantation; Metoprolol; Nifedipine; Propranolol | 1988 |
Influence of long-term antihypertensive therapy on cardiac function, coronary flow and myocardial oxygen consumption in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Coronary Circulation; Felodipine; Heart; Heart Rate; Hypertension; Male; Metoprolol; Myocardium; Nifedipine; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke Volume; Time Factors; Vascular Resistance | 1986 |
Neuropeptide Y and sympathetic control of heart contractility and coronary vascular tone.
Topics: Animals; Arginine Vasopressin; Atropine; Coronary Vessels; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Metoprolol; Muscle, Smooth, Vascular; Myocardial Contraction; Nerve Tissue Proteins; Neuropeptide Y; Nifedipine; Norepinephrine; Phentolamine; Tetrodotoxin | 1985 |
Addition of nifedipine to maximal beta-blocker-nitrate therapy: effects on exercise capacity and global left ventricular performance at rest and during exercise.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Electrocardiography; Female; Heart Rate; Humans; Isosorbide; Male; Metoprolol; Middle Aged; Nadolol; Nifedipine; Nitroglycerin; Physical Exertion; Propanolamines; Propranolol; Radionuclide Imaging; Rest | 1985 |
Improvement in exercise capacity and associated changes in hemodynamics and left ventricular function after the addition of metoprolol to nifedipine in patients with stable exertional angina.
Topics: Administration, Oral; Adult; Angina Pectoris; Cardiac Output; Drug Therapy, Combination; Electrocardiography; Exercise Test; Heart Ventricles; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Nifedipine | 1985 |
Effect of felodipine and metoprolol on muscle and skin arteries in hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Felodipine; Female; Heart Rate; Humans; Hyperemia; Hypertension; Male; Metoprolol; Middle Aged; Muscle, Smooth, Vascular; Muscles; Nifedipine; Physical Exertion; Posture; Regional Blood Flow; Skin; Vascular Resistance | 1985 |
Electrophysiological effects of felodipine in combination with metoprolol.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Drug Synergism; Electrocardiography; Electrophysiology; Felodipine; Female; Heart Conduction System; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Purkinje Fibers; Vasodilator Agents | 1985 |
Study of the influence of nifedipine on the pharmacokinetics and pharmacodynamics of propranolol, metoprolol and atenolol.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Drug Interactions; Humans; Kinetics; Male; Metoprolol; Nifedipine; Propranolol | 1984 |
The influence of two histamine H2-receptor antagonists, cimetidine and ranitidine, on the plasma levels and clinical effect of nifedipine and metoprolol.
Topics: Adult; Cimetidine; Drug Interactions; Histamine H2 Antagonists; Humans; Male; Metoprolol; Nifedipine; Ranitidine | 1984 |
Regression of structural cardiovascular changes by antihypertensive therapy in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cardiovascular System; Circadian Rhythm; Felodipine; Heart Rate; Hypertension; Methyldopa; Metoprolol; Nifedipine; Rats; Rats, Inbred SHR; Time Factors | 1984 |
Treatment of unstable angina with emphasis on calcium antagonists.
Topics: Angina Pectoris; Angina, Unstable; Anticoagulants; Coronary Circulation; Coronary Disease; Electrocardiography; Humans; Isosorbide Dinitrate; Metoprolol; Nifedipine; Nitroglycerin; Oxygen Consumption; Propranolol; Verapamil | 1984 |
Antianginal drug effects on normal, ischemic and scar myocardial segments in man.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Female; Heart; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Nifedipine; Nitroglycerin; Physical Exertion; Stroke Volume | 1984 |
Lack of a pharmacokinetic interaction between nifedipine and the beta-adrenoceptor blockers metoprolol and atenolol.
Topics: Adult; Atenolol; Drug Interactions; Female; Half-Life; Humans; Kinetics; Metoprolol; Nifedipine | 1984 |
Myocardial infarct size limitation. Principles, problems and possibilities.
Topics: Allopurinol; Animals; Coronary Circulation; Dogs; Flurbiprofen; Humans; Metoprolol; Myocardial Infarction; Nifedipine; Tetrazolium Salts; Verapamil | 1984 |
The effect on left ventricular performance of nifedipine and metoprolol singly and together in exercise-induced angina pectoris.
Topics: Adult; Angina Pectoris; Cardiac Output; Drug Therapy, Combination; Heart Ventricles; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Physical Exertion; Rest | 1984 |
Prinzmetal's variant angina.
Topics: Aged; Angina Pectoris; Angina Pectoris, Variant; Diagnosis, Differential; Electrocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Nitroglycerin; Propranolol; Verapamil | 1981 |
Benefits from adding nifedipine to the treatment of unstable angina when beta-blockade and isosorbide dinitrate have proved inadequate.
Topics: Aged; Angina Pectoris, Variant; Coronary Disease; Coronary Vasospasm; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Nifedipine; Nitroglycerin; Physical Exertion; Propanolamines; Pyridines | 1982 |
Elevated plasma atrial natriuretic peptide concentrations in hypertensive patients with acute myocardial infarction.
Topics: Acebutolol; Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Cardiac Output, Low; Creatine Kinase; Creatinine; Echocardiography; Female; Furosemide; Heart Atria; Heart Ventricles; Humans; Hypertension; Isoenzymes; Male; Metoprolol; Middle Aged; Myocardial Infarction; Nifedipine; Potassium; Sodium | 1995 |
[Effects of calcium antagonists on withdrawal of beta-receptor blockers in rats during left ventricular hypertrophy].
Topics: Animals; Hemodynamics; Hypertrophy, Left Ventricular; Isomerism; Male; Metoprolol; Myocardium; Nifedipine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Substance Withdrawal Syndrome | 1995 |
Poisoning caused by the combined ingestion of nifedipine and metoprolol.
Topics: Administration, Oral; Adult; Calcium Chloride; Diazepam; Drug Combinations; Gastric Lavage; Humans; Male; Methylprednisolone; Metoprolol; Nifedipine; Tranquilizing Agents | 1993 |
Effect of antihypertensive drugs on glomerular hyperfiltration and renal haemodynamics. Comparison of captopril with nifedipine, metoprolol and celiprolol.
Topics: Antihypertensive Agents; Captopril; Celiprolol; Dietary Proteins; Glomerular Filtration Rate; Humans; Insulin; Metoprolol; Nifedipine; p-Aminohippuric Acid; Renal Circulation; Stimulation, Chemical | 1993 |
Comparison of nifedipine and metoprolol on collateral coronary blood flow in a swine model of chronic coronary obstruction and acute ischaemia during isoflurane anaesthesia.
Topics: Adrenergic beta-Antagonists; Anesthetics, Inhalation; Animals; Calcium Channel Blockers; Chronic Disease; Collateral Circulation; Coronary Circulation; Coronary Disease; Drug Interactions; Isoflurane; Metoprolol; Myocardial Ischemia; Nifedipine; Swine | 1996 |
[Stable angina pectoris: what is the role of calcium antagonists?].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Felodipine; Humans; Metoprolol; Multicenter Studies as Topic; Nifedipine; Randomized Controlled Trials as Topic; Verapamil | 1997 |
Measurement of left ventricular maximal isovolumetric pressure in rats: effects of antihypertensive drugs and diabetes mellitus.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Catheterization; Diabetes Mellitus, Experimental; Female; Losartan; Metoprolol; Nifedipine; Prazosin; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Ventricular Function, Left; Ventricular Pressure | 1998 |
Effects of antihypertensive drugs on cholesterol metabolism of human mononuclear leukocytes and hepatoma cells.
Topics: Antihypertensive Agents; Carcinoma, Hepatocellular; Cholesterol; Diltiazem; Humans; Leukocytes, Mononuclear; Liver Neoplasms; Metoprolol; Nifedipine; Propranolol; Tumor Cells, Cultured; Verapamil | 1998 |
Endothelin converting-enzyme-1 mRNA expression in human cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Aspartic Acid Endopeptidases; Calcium Channel Blockers; Cardiovascular Diseases; Endothelin-Converting Enzymes; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Heart Atria; Humans; Male; Metalloendopeptidases; Metoprolol; Middle Aged; Myocardium; Nifedipine; RNA, Messenger | 1998 |
[Antioxidant effect of drugs used in cardiovascular therapy].
Topics: Adrenergic beta-Antagonists; Antioxidants; Ascorbic Acid; Atenolol; Calcium Channel Blockers; Copper; Female; Fluorescence; Humans; Lipid Peroxidation; Male; Metoprolol; Nifedipine; Pindolol; Propranolol | 1998 |
Inhibitory effects of carvedilol on calcium channels in vascular smooth muscle cells.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aorta; Calcium; Calcium Channels; Calcium Signaling; Carbazoles; Carvedilol; Cell Division; Endothelin-1; Metoprolol; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Propanolamines; Rats; Vasodilator Agents; Vasopressins | 2003 |
Autonomic antecedents to variant angina exacerbation after beta-blockade withdrawal.
Topics: Adrenergic beta-Antagonists; Angina Pectoris, Variant; Autonomic Nervous System; Coronary Vasospasm; Electrocardiography; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Nitrates; Substance Withdrawal Syndrome; Vasodilator Agents | 2005 |
[Ischemic disease of the kidneys in a patient with morbid obesity: characteristics of the course and diagnostic policy].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Diagnosis, Differential; Health Policy; Humans; Ischemia; Kidney Diseases; Male; Metoprolol; Middle Aged; Nifedipine; Obesity | 2006 |
Renovascular hypertension in a child with Marfan syndrome.
Topics: Adolescent; Angiography, Digital Subtraction; Blood Pressure; Female; Humans; Hypertension, Renovascular; Marfan Syndrome; Metoprolol; Nifedipine; Renal Artery Obstruction; Treatment Outcome; Vasodilator Agents | 2010 |
Simultaneous delivery of Nifedipine and Metoprolol tartarate using sandwiched osmotic pump tablet system.
Topics: Administration, Oral; Antihypertensive Agents; Chemistry, Pharmaceutical; Drug Combinations; Drug Compounding; Drug Delivery Systems; Excipients; Hydrogen-Ion Concentration; Metoprolol; Nifedipine; Osmotic Pressure; Predictive Value of Tests; Solubility; Tablets, Enteric-Coated | 2010 |
Influence of drug treatment on glucocorticoid receptor levels in patients with coronary heart disease.
Topics: Aged; Blotting, Western; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Lovastatin; Male; Metoprolol; Middle Aged; Nifedipine; Receptors, Glucocorticoid | 2010 |
Changes induced by estradiol-ethylenediamine derivative on perfusion pressure and coronary resistance in isolated rat heart: L-type calcium channel.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Coronary Circulation; Cyclooxygenase Inhibitors; Estradiol; Estrogen Antagonists; Ethylenediamines; Female; In Vitro Techniques; Indomethacin; Metoprolol; Myocardium; Nifedipine; Prazosin; Rats; Rats, Wistar; Tamoxifen; Vascular Resistance | 2011 |
Development and evaluation of controlled porosity osmotic pump for nifedipine and metoprolol combination.
Topics: Drug Delivery Systems; Metoprolol; Nifedipine; Porosity; Tablets | 2011 |
Positive inotropic activity induced by a dehydroisoandrosterone derivative in isolated rat heart model.
Topics: Androgen Antagonists; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiotonic Agents; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Flutamide; In Vitro Techniques; Male; Metoprolol; Models, Animal; Nifedipine; Prazosin; Rats; Ventricular Function, Left | 2013 |
Intralipid emulsion treatment as an antidote in lipophilic drug intoxications.
Topics: Adolescent; Adult; Alprazolam; Amitriptyline; Antidotes; Blood Pressure; Dibenzothiazepines; Drug Overdose; Fat Emulsions, Intravenous; Female; Fluoxetine; Glasgow Coma Scale; Heart Rate; Humans; Lamotrigine; Lipid Metabolism; Male; Metoprolol; Middle Aged; Nifedipine; Quetiapine Fumarate; Triazines; Young Adult | 2014 |
Human in vivo regional intestinal permeability: quantitation using site-specific drug absorption data.
Topics: Budesonide; Colon; Cyclosporine; Fenofibrate; Humans; Intestinal Absorption; Intestinal Mucosa; Lisdexamfetamine Dimesylate; Metoprolol; Nifedipine; Pyrimidines; Ranitidine; Rivastigmine; Sumatriptan; Terfenadine; Theophylline | 2015 |
Prediction of drug interaction between oral adsorbent AST-120 and concomitant drugs based on the in vitro dissolution and in vivo absorption behavior of the drugs.
Topics: Administration, Oral; Adsorption; Aluminum Hydroxide; Amlodipine; Aspirin; Carbon; Drug Interactions; Glycine; Humans; Intestinal Absorption; Losartan; Magnesium; Metoprolol; Models, Biological; Nifedipine; Oxides; Renal Insufficiency, Chronic; Solubility; Triazolam | 2016 |
A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways.
Topics: Caffeine; Cytochrome P-450 Enzyme System; Diazepam; Female; Granisetron; Humans; Metoprolol; Metronidazole; Midazolam; Models, Biological; Nifedipine; Ondansetron; Pharmaceutical Preparations; Pregnancy | 2018 |
Evaluation of anticholinergic burden in elderly outpatients and the risk factors.
Topics: Aged; Alprazolam; Cholinergic Antagonists; Eszopiclone; Humans; Metoprolol; Nifedipine; Outpatients; Risk Factors; Sleep Initiation and Maintenance Disorders | 2023 |