nifedipine and mepirodipine

nifedipine has been researched along with mepirodipine in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.90)	18.7374
1990's	29 (42.03)	18.2507
2000's	19 (27.54)	29.6817
2010's	17 (24.64)	24.3611
2020's	2 (2.90)	2.80

Authors

Authors	Studies
Horinouchi, M; Komada, F; Nishiguchi, K; Ohmoto, N; Ohnishi, N; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y; Yokoyama, T	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Inagaki, O; Kato, Y; Kimura, R; Matsuoka, Y; Yamada, S	1
Kato, Y; Kimura, R; Matsuoka, Y; Sugimoto, N; Suzuki, N; Yamada, S	1
Fujita, T; Noda, H; Ogata, E	1
Hashimoto, K; Satoh, H	1
Fujimoto, K; Inagaki, O; Kawashima, K; Oohata, H; Suzuki, T; Toda, H	1
Hashimoto, K; Motomura, S	1
Higuchi, S; Kobayashi, S; Teramura, T	1
Kashiwabara, T; Nakayama, K; Tanaka, Y; Yamada, S	1
Arima, H; Fujita, S; Furuya, T; Inagaki, O; Isomura, Y; Kojima, T; Okada, M; Takenaka, T; Tamazawa, K; Terai, M	1
Caro, CG; Hiramatsu, O; Jones, CJ; Kajiya, F; Lever, MJ; Ogasawara, Y; Parker, KH; Takenaka, T; Tsujioka, K	1
Inagaki, O; Shibasaki, M; Takenaka, T	1
Kimura, R; Matsuoka, Y; Yamada, S	1
Hashimoto, K; Higuchi, S; Teramura, T; Watanabe, T	2
Abdel-Wadood, HM; el-Rabbat, NA; Kusu, F; Otagiri, M; Rafaat, IH; Saleh, GA; Takamura, K	1
Higuchi, S; Matsumoto, H; Teramura, T; Tokunaga, T; Watanabe, T	1
Asano, M; Ishikawa, J; Kasai, C; Masaki, K; Saitoh, M	1
Akaishi, M; Mitamura, H; Ogawa, S; Oyamada, K; Soejima, K	1
Fukunaga, Y; Higuchi, S; Teramura, T; Van Hoogdalem, EJ; Watanabe, T	1
Abe, K; Imai, Y; Nishiyama, A; Sekino, M; Yoshinaga, K	1
Hart, W; Holwerda, NJ	1
van Zwieten, PA	1
Argenziano, L; De Luca, N; Iovino, G; Izzo, R; Morisco, C; Parrella, L; Trimarco, B	1
Spieker, C	1
Beudeker, HJ; Nishi, M; van der Velden, JW	1
Awata, T; Inaba, M; Katayama, S; Kosegawa, I; Morita, T	1
Cheng, KN; Higuchi, S; Pawula, M; Teramura, T; Watanabe, T; Watson, D	1
Asano, M; Inagaki, O; Takenaka, T	1
Becker, BF; Möbert, J	1
Hashimoto, M; Kashihara, N; Makino, H; Mimura, Y; Ogura, T; Oishi, T; Otsuka, F; Yamauchi, T	1
Abe, I; Fujii, K; Fujishima, M; Fujishima-Nakao, Y; Kagiyama, S; Ohta, Y; Ohya, Y; Onaka, U	1
Meyrer, H; Nawrath, H; Rupp, J; Wegener, JW	1
Hanafusa, T; Horikawa, Y; Iizuka, K; Imagawa, A; Kuwajima, M; Matsuzawa, Y; Miyagawa, J; Nakajima, H; Namba, M; Shiba, E; Takai, S; Tomita, K	1
Birkenhäger, WH	1
Otterstad, JE; Ruilope, LM	1
Korstanje, C	1
Smilde, JG	1
Häge, R; Mortelmans, J; Naber, FB	1
Beudeker, HJ; van der Aar, EM; van der Velden, JW	1
Trimarco, B	1
Malhotra, HS; Plosker, GL	1
Kajiya, F; Tanaka, H; Tomura, Y; Yamamoto, T	1
Janssen, BJ; Kam, KL; Smits, JF	1
Abe, K; Kuwajima, I	1
Korstanje, C; Nawrath, H; Wegener, JW	1
Liau, CS	1
Hattori, M; Hirakura, Y; Kajiyama, A; Miyanishi, H; Mizuno, M; Yamane, I; Yokota, S	1
Achimastos, A; Elisaf, M; Kolaitis, N; Liberopoulos, EN; Rizos, E; Spirou, A; Tselepis, AD	1
Corretti, V; Fraser, AG; Kozakova, M; Malshi, E; Morizzo, C; Palombo, C; Rakebrandt, F; Santini, F	1
Altay, S; Gürkan, U; Güvenç, TS; Güzelburç, O; Ilhan, E	1
Cagnoni, F; Destro, M; Giglio, A; Grandi, AM; Lonati, L; Maresca, AM; Monza, M; Omboni, S; Parati, G; Pini, C; Ricci, AR; Venco, A	1
Belotti, E; Boari, GE; de Ciuceis, C; Muiesan, ML; Paini, A; Pilu, A; Porteri, E; Rizzoni, D; Rosei, CA; Rosei, EA; Salvetti, M; Zani, F	1
Aggiusti, C; Belotti, E; de Ciuceis, C; Muiesan, ML; Paini, A; Rizzoni, D; Rosei, CA; Rosei, EA; Salvetti, M; Scotti, A	1
De Luca, M; Ioele, G; Ragno, G	1
Cheng, ZG; Dai, XY; Li, LW; Ma, X; Wan, Q; Xiang, GY	1
Lins, R; Marckx, P; Neuville, O; Vandebeek, R; Vanhoutvinck, C	1
D'Angelo, A; Dario Ragonesi, P; Derosa, G; Franzetti, I; Maffioli, P; Querci, F	1
Alp Yildirim, FI; Balci Ekmekçi, Ö; Demirci Tansel, C; Eker Kizilay, D; Ergin, B; Kucur, M; Topal, G; Uydeş Doğan, BS	1
D'Angelo, A; Derosa, G; Franzetti, I; Maffioli, P; Mugellini, A; Pesce, RM; Querci, F	1
D'Angelo, A; Derosa, G; Maffioli, P; Mugellini, A; Pesce, RM	2
Bravi, E; Cassi, A; Crippa, G; Zabzuni, D	1
de Vries, C; Haerden, Y; Lins, R	1
Acone, B; Calcullo, C; Crippa, M; De Luca, N; Desideri, G; Gaudio, GV; Lonati, LM; Orselli, L; Roca, E; Scuteri, A; Tocci, G; Vulpis, V; Zaninelli, A	1
Okyar, A; Ozturk, D; Ozturk, N; Pala-Kara, Z	1
Bender, A; Chen, X; Li, Y; Meng, Q; Yang, J; Zhang, Y	1
Chaudhari, SR; Shirkhedkar, AA	1

Reviews

6 review(s) available for nifedipine and mepirodipine

Article	Year
Pharmacological profile of barnidipine: a single optical isomer dihydropyridine calcium antagonist. Blood pressure. Supplement, 1998, Volume: 1 Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Guinea Pigs; Hypertension; Nifedipine; Rats; Rats, Inbred SHR; Structure-Activity Relationship	1998
Barnidipine, a long-acting slow onset calcium antagonist. International journal of clinical practice. Supplement, 2000, Issue:114 Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Guinea Pigs; Humans; Hypertension; Nifedipine; Rats; Swine	2000
Interaction profile and tolerability of barnidipine. International journal of clinical practice. Supplement, 2000, Issue:114 Topics: Aged; Calcium Channel Blockers; Drug Interactions; Humans; Hypertension; Middle Aged; Nifedipine	2000
Barnidipine. Drugs, 2001, Volume: 61, Issue:7 Topics: Aged; Animals; Area Under Curve; Biological Availability; Calcium Channel Blockers; Hemodynamics; Humans; Hypertension; Intestinal Absorption; Multicenter Studies as Topic; Nifedipine; Randomized Controlled Trials as Topic	2001
Barnidipine: a new calcium channel blocker for hypertension treatment. Expert review of cardiovascular therapy, 2005, Volume: 3, Issue:2 Topics: Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hypertension; Nifedipine	2005
How to Improve Effectiveness and Adherence to Antihypertensive Drug Therapy: Central Role of Dihydropyridinic Calcium Channel Blockers in Hypertension. High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2018, Volume: 25, Issue:1 Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Essential Hypertension; Humans; Medication Adherence; Nifedipine; Risk Factors; Treatment Outcome; Vasodilator Agents	2018

Trials

17 trial(s) available for nifedipine and mepirodipine

Article	Year
Barnidipine, a novel calcium antagonist for once-daily treatment of hypertension: a multicenter, double-blind, placebo-controlled, dose-ranging study. Dutch Barnidipine Multicenter Study Group. Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:5 Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Edema; Female; Flushing; Headache; Humans; Hypertension; Male; Middle Aged; Nifedipine	1997
Distinct vasodilation, without reflex neurohormonal activation, induced by barnidipine in hypertensive patients. Blood pressure. Supplement, 1998, Volume: 1 Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Reflex; Sympathetic Nervous System; Vasodilation	1998
Natriuretic effect of barnidipine, a long-acting dihydropyridine calcium channel blocker, in patients with essential hypertension. International journal of clinical pharmacology and therapeutics, 2000, Volume: 38, Issue:6 Topics: Adult; Aged; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Natriuresis; Nifedipine; Single-Blind Method	2000
Treatment of hypertension in the very old. International journal of clinical practice. Supplement, 2000, Issue:114 Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Nifedipine; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Treatment Outcome	2000
The long-term efficacy and safety profile of barnidipine. International journal of clinical practice. Supplement, 2000, Issue:114 Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Treatment Outcome	2000
Barnidipine monotherapy and combination therapy in older patients with essential hypertension: a long-term study. International journal of clinical practice. Supplement, 2000, Issue:114 Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Nifedipine; Treatment Outcome	2000
Are there any relevant differences within the calcium antagonist class? International journal of clinical practice. Supplement, 2000, Issue:114 Topics: Adolescent; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Humans; Hypertension; Middle Aged; Nifedipine; Nitrendipine; Treatment Outcome	2000
Effects of the long-acting calcium channel blocker barnidipine hydrochloride on 24-h ambulatory blood pressure. Blood pressure monitoring, 2002, Volume: 7, Issue:1 Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Delayed-Action Preparations; Humans; Japan; Nifedipine	2002
Effect of barnidipine on blood pressure and serum metabolic parameters in patients with essential hypertension: a pilot study. Journal of cardiovascular pharmacology and therapeutics, 2006, Volume: 11, Issue:4 Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Aged; Antihypertensive Agents; Aryldialkylphosphatase; Blood Coagulation; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Electrolytes; Female; Fibrinolysis; Greece; Humans; Hypertension; Isoprostanes; Kidney Function Tests; Lipids; Male; Middle Aged; Nifedipine; Oxidative Stress; Phospholipases A2; Pilot Projects; Time Factors; Treatment Outcome	2006
Arterial wave reflection during antihypertensive therapy with barnidipine: a 6-month, open-label study using an integrated cardiovascular ultrasound approach in patients with newly diagnosed hypertension. Clinical therapeutics, 2009, Volume: 31, Issue:12 Topics: Aged; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Carotid Arteries; Echocardiography, Doppler; Elasticity; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Severity of Illness Index; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Color; Ventricular Function, Left	2009
Effectiveness of barnidipine 10 or 20 mg plus losartan 50-mg combination versus losartan 100-mg monotherapy in patients with essential hypertension not controlled by losartan 50-mg monotherapy: A 12-week, multicenter, randomized, open-label, parallel-grou Clinical therapeutics, 2010, Volume: 32, Issue:7 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Nifedipine	2010
Effect of antihypertensive treatment on circulating endothelial progenitor cells in patients with mild essential hypertension. Blood pressure, 2011, Volume: 20, Issue:2 Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Endothelial Cells; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Stem Cells	2011
Effects of barnidipine in comparison with hydrochlorothiazide on endothelial function, as assessed by flow mediated vasodilatation in hypertensive patients. Blood pressure, 2011, Volume: 20, Issue:4 Topics: Adult; Aged; Antihypertensive Agents; Brachial Artery; Calcium Channel Blockers; Endothelium, Vascular; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Vasodilation	2011
Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus. Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:10 Topics: Adipokines; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Combinations; Female; Glucose Clamp Technique; Humans; Hydrochlorothiazide; Hypertension; Insulin Resistance; Losartan; Male; Middle Aged; Nifedipine; Telmisartan	2015
Barnidipine or Lercanidipine on Echocardiographic Parameters in Hypertensive, Type 2 Diabetics with Left Ventricular Hypertrophy: A Randomized Clinical Trial. Scientific reports, 2015, Aug-05, Volume: 5 Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Middle Aged; Nifedipine; Treatment Outcome	2015
Perindopril and barnidipine alone or combined with simvastatin on hepatic steatosis and inflammatory parameters in hypertensive patients. European journal of pharmacology, 2015, Nov-05, Volume: 766 Topics: Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Hypolipidemic Agents; Male; Nifedipine; Non-alcoholic Fatty Liver Disease; Obesity; Perindopril; Simvastatin	2015
Barnidipine compared to lercanidipine in addition to losartan on endothelial damage and oxidative stress parameters in patients with hypertension and type 2 diabetes mellitus. BMC cardiovascular disorders, 2016, Apr-12, Volume: 16 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Hypertension; Italy; Losartan; Male; Middle Aged; Nifedipine; Oxidative Stress; Time Factors; Treatment Outcome	2016

Other Studies

46 other study(ies) available for nifedipine and mepirodipine

Article	Year
Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2002, Volume: 16, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Digoxin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Gene Expression; Humans; Nifedipine; Paclitaxel; RNA, Messenger; Swine; Tritium; Tumor Cells, Cultured; Verapamil; Vinblastine	2002
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
A sustained occupancy in vivo of cardiovascular calcium antagonist receptors by mepirodipine and its relation to pharmacodynamic effect in spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2 Topics: Animals; Binding Sites; Blood Pressure; Brain; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Hypertension; Isradipine; Male; Myocardium; Nifedipine; Rats; Rats, Inbred SHR; Receptors, Nicotinic	1992
Determination of a novel calcium channel antagonist, mepirodipine, in plasma by radioreceptor assay using (+)-[3H]PN 200-110. Pharmaceutical research, 1992, Volume: 9, Issue:9 Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; In Vitro Techniques; Isradipine; Male; Nifedipine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Regression Analysis; Reproducibility of Results	1992
The role of renal hemodynamics in the antihypertensive action of mepirodipine, a new calcium antagonist. Japanese circulation journal, 1992, Volume: 56, Issue:1 Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Forearm; Hemodynamics; Humans; Hypertension; Liver Circulation; Middle Aged; Nifedipine; Renal Circulation; Vascular Resistance	1992
Comparative effects of a new calcium channel antagonist, mepirodipine, on rabbit spontaneously beating sino-atrial node cells. European journal of pharmacology, 1991, Jan-25, Volume: 193, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Diltiazem; Female; In Vitro Techniques; Male; Nifedipine; Rabbits; Sinoatrial Node; Verapamil	1991
Antihypertensive and diuretic effects of YM-09730-5, a new calcium antagonist, in stroke-prone spontaneously hypertensive rats. General pharmacology, 1991, Volume: 22, Issue:2 Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Diuresis; Diuretics; Heart Rate; Hypertension; Male; Nicardipine; Nifedipine; Organ Size; Rats; Rats, Inbred SHR; Renin; Urodynamics	1991
Reconsideration of vascular selectivity of dihydropyridine calcium antagonists: comparison of cardiovascular profile of mepirodipine, a novel dihydropyridine consisting of a single stereoisomer with (+)-(S)-(S) conformation, with those of nifedipine and n Japanese journal of pharmacology, 1990, Volume: 52, Issue:2 Topics: Animals; Atrioventricular Node; Calcium Channel Blockers; Coronary Circulation; Dogs; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Nicardipine; Nifedipine; Papillary Muscles; Sinoatrial Node; Stereoisomerism	1990
Determination of mepirodipine in plasma by capillary column gas chromatography-negative-ion chemical ionization mass spectrometry. Journal of chromatography, 1990, Jun-08, Volume: 528, Issue:1 Topics: Calcium Channel Blockers; Deuterium; Drug Stability; Gas Chromatography-Mass Spectrometry; Humans; Microchemistry; Nifedipine	1990
Assessment in pig coronary artery of long-lasting and potent calcium antagonistic actions of the novel dihydropyridine derivative mepirodipine hydrochloride. Arzneimittel-Forschung, 1989, Volume: 39, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Coronary Vessels; Female; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium Chloride; Swine	1989
Stereoselectivity of a potent calcium antagonist, 1-benzyl-3-pyrrolidinyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. Journal of medicinal chemistry, 1986, Volume: 29, Issue:12 Topics: Animals; Blood Pressure; Brain; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Coronary Circulation; Coronary Vessels; Dogs; Heart Rate; Male; Molecular Conformation; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship; Vasodilation	1986
Influence of heart rate and vasoactive drugs on blood flow patterns at the canine ilio-femoral bifurcation. Cardiovascular research, 1994, Volume: 28, Issue:11 Topics: Angiotensin II; Animals; Blood Flow Velocity; Calcium Channel Blockers; Dogs; Female; Femoral Artery; Heart Rate; Iliac Artery; Male; Nifedipine; Nitroglycerin; Regional Blood Flow; Ultrasonography, Doppler, Pulsed	1994
Hemodynamic effects of barnidipine hydrochloride in conscious squirrel monkeys. General pharmacology, 1994, Volume: 25, Issue:3 Topics: Animals; Blood Pressure; Calcium Channel Blockers; Electrocardiography; Female; Heart Rate; Male; Molecular Structure; Nifedipine; Renin-Angiotensin System; Saimiri	1994
Correlation between the plasma concentration of mepirodipine and its occupancy of Ca2+ antagonist receptors in rats. Pharmaceutical research, 1993, Volume: 10, Issue:9 Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Isradipine; Male; Myocardium; Nifedipine; Radioligand Assay; Rats; Rats, Wistar	1993
Pharmacokinetics of barnidipine hydrochloride, a new dihydropyridine calcium channel blocker, in the rat, dog and human. Xenobiotica; the fate of foreign compounds in biological systems, 1995, Volume: 25, Issue:11 Topics: Administration, Oral; Animals; Biological Availability; Calcium Channel Blockers; Dogs; Half-Life; Humans; Injections, Intravenous; Kinetics; Male; Molecular Structure; Nifedipine; Rats; Stereoisomerism	1995
Determination of barnidipine in human serum and dog plasma by HPLC with electrochemical detection. Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:10 Topics: Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dogs; Electrochemistry; Humans; Indicators and Reagents; Nifedipine; Photochemistry	1995
Metabolism of barnidipine hydrochloride, a potent calcium antagonist, in rat and dog. Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:2 Topics: Animals; Bile; Biotransformation; Calcium Channel Blockers; Cytosol; Dogs; In Vitro Techniques; Liver; Male; Microsomes, Liver; Nifedipine; Rats; Rats, Inbred F344; Species Specificity; Spectrometry, Mass, Fast Atom Bombardment; Subcellular Fractions	1996
Metabolism and pharmacokinetics of barnidipine hydrochloride, a calcium channel blocker, in man following oral administration of its sustained release formulation. Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:2 Topics: Administration, Oral; Adult; Calcium Channel Blockers; Humans; Male; Molecular Structure; Nifedipine	1997
Effect of barnidipine on blood flow to major organs and renal function in anaesthetized dogs and spontaneously hypertensive rats. Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1 Topics: Anesthesia; Animals; Antihypertensive Agents; Calcium Channel Blockers; Diuresis; Dogs; Female; Hypertension; Kidney; Male; Nifedipine; Rats; Rats, Inbred SHR; Regional Blood Flow; Renal Circulation; Urodynamics; Vascular Resistance	1995
[Effect of barnidipine hydrochloride on the autonomic nervous system: difference between short- and long-acting components of calcium antagonist]. Journal of cardiology, 1997, Volume: 30, Issue:1 Topics: Autonomic Nervous System; Blood Pressure; Calcium Channel Blockers; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Male; Middle Aged; Nifedipine	1997
Examination of metabolic pathways and identification of human liver cytochrome P450 isozymes responsible for the metabolism of barnidipine, a calcium channel blocker. Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:9 Topics: Calcium Channel Blockers; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Liver; Mass Spectrometry; Microsomes, Liver; NADP; Nifedipine	1997
Evaluation of the antihypertensive effect of barnidipine, a dihydropyridine calcium entry blocker, as determined by the ambulatory blood pressure level averaged for 24 h, daytime, and nighttime. Barnidipine Study Group. American journal of hypertension, 1997, Volume: 10, Issue:12 Pt 1 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine	1997
Efficacy and tolerability of once-daily barnidipine in the clinical management of patients with mild to moderate essential hypertension. Blood pressure. Supplement, 1998, Volume: 1 Topics: Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hypertension; Multicenter Studies as Topic; Nifedipine; Randomized Controlled Trials as Topic; Treatment Outcome	1998
Diversity and intensity of adverse events in the treatment of hypertension with barnidipine. Blood pressure. Supplement, 1998, Volume: 1 Topics: Aged; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Treatment Outcome	1998
Effect of the vasodilatory beta-blocker, nipradilol, and Ca-antagonist, barnidipine, on insulin sensitivity in patients with essential hypertension. Clinical and experimental hypertension (New York, N.Y. : 1993), 1998, Volume: 20, Issue:7 Topics: Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers; Female; Glucose Clamp Technique; Humans; Hypertension; Insulin Resistance; Male; Middle Aged; Nifedipine; Propanolamines; Vasodilator Agents	1998
Sensitive and specific liquid chromatographic-tandem mass spectrometric assay for barnidipine in human plasma. Journal of chromatography. B, Biomedical sciences and applications, 1998, Nov-20, Volume: 719, Issue:1-2 Topics: Calcium Channel Blockers; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Nifedipine; Reproducibility of Results; Sensitivity and Specificity	1998
In vitro and in vivo vasodilatory activity of barnidipine and its enantiomers. Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:2 Topics: Animals; Aorta; Atrial Function; Dogs; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Muscle Contraction; Nifedipine; Regional Blood Flow; Stereoisomerism; Vasodilator Agents	1999
Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion. Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:3 Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dose-Response Relationship, Drug; Energy Metabolism; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Purines; Pyruvates	1999
Treatment with a Ca(2+) channel blocker, barnidipine, reduces platelet-derived growth factor B-chain mRNA in glomeruli of spontaneously hypertensive rats. American journal of nephrology, 1999, Volume: 19, Issue:5 Topics: Animals; Blood Pressure; Calcium Channel Blockers; Gene Expression; Heart Rate; Hypertension; Kidney Glomerulus; Male; Nifedipine; Organ Size; Proto-Oncogene Proteins c-sis; Rats; Rats, Inbred SHR; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Treatment Outcome	1999
Barnidipine block of L-type Ca(2+) channel currents in rat ventricular cardiomyocytes. British journal of pharmacology, 2000, Volume: 130, Issue:8 Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart Ventricles; Male; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Time Factors; Ventricular Function	2000
In vivo effects of calcium entry blockers on human parathyroid adenoma cells with special reference to calcium sensing ability and the hormone secretion. Research communications in molecular pathology and pharmacology, 1999, Volume: 106, Issue:1-2 Topics: Adenoma; Calcium; Calcium Channel Blockers; Humans; Microscopy, Confocal; Microscopy, Fluorescence; Nifedipine; Parathyroid Hormone; Parathyroid Neoplasms; Tumor Cells, Cultured	1999
Barnidipine: a step towards safer blood pressure control? International journal of clinical practice. Supplement, 2000, Issue:114 Topics: Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Nifedipine	2000
In vivo visualization of characteristics of renal microcirculation in hypertensive and diabetic rats. American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:3 Topics: Animals; Arterioles; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Hemodynamics; Hypertension; Kidney Glomerulus; Male; Microcirculation; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Vasoconstriction; Vasodilation	2001
Preferential renal and mesenteric vasodilation induced by barnidipine and amlodipine in spontaneously hypertensive rats. Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 364, Issue:5 Topics: Amlodipine; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Hemodynamics; Male; Nifedipine; Rats; Rats, Inbred SHR; Renal Circulation; Splanchnic Circulation; Stereoisomerism; Vasodilation	2001
Voltage-dependent effects of barnidipine in rat vascular smooth muscle. Journal of cardiovascular pharmacology, 2003, Volume: 42, Issue:2 Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Female; Male; Muscle, Smooth, Vascular; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley	2003
Inhibition of a solid phase reaction among excipients that accelerates drug release from a solid dispersion with aging. International journal of pharmaceutics, 2005, Nov-23, Volume: 305, Issue:1-2 Topics: Carboxymethylcellulose Sodium; Drug Stability; Drug Storage; Excipients; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Molecular Weight; Nifedipine; Solubility; Solvents; Technology, Pharmaceutical; Temperature; Time Factors	2005
Barnidipine intoxication causing acute myocardial infarction. The American journal of emergency medicine, 2010, Volume: 28, Issue:4 Topics: Adult; Calcium Channel Blockers; Coronary Angiography; Electrocardiography; Female; Humans; Myocardial Infarction; Nifedipine; Suicide, Attempted	2010
Photostability of barnidipine in combined cyclodextrin-in-liposome matrices. Future medicinal chemistry, 2014, Volume: 6, Issue:1 Topics: Chemistry, Pharmaceutical; Cyclodextrins; Ethanol; Light; Liposomes; Nifedipine; Photolysis; Spectrophotometry	2014
Synthesis and characterization of impurities of barnidipine hydrochloride, an antihypertensive drug substance. Molecules (Basel, Switzerland), 2014, Jan-21, Volume: 19, Issue:1 Topics: Antihypertensive Agents; Calcium Channel Blockers; Drug Contamination; Molecular Structure; Nifedipine; Nuclear Magnetic Resonance, Biomolecular	2014
Barnidipine real-life tolerability in arterial hypertension: results from the BASIC-HT study. Acta clinica Belgica, 2015, Volume: 70, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Nifedipine; Young Adult	2015
Barnidipine ameliorates the vascular and renal injury in L-NAME-induced hypertensive rats. European journal of pharmacology, 2015, Oct-05, Volume: 764 Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Inflammation Mediators; Kidney; Kidney Diseases; Male; Malondialdehyde; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxidase; Rats, Wistar; Renal Artery; Time Factors; Vascular Remodeling; Vasoconstriction; Vasodilation	2015
Effect of bedtime dosing of barnidipine hydrochloride in non-dipper hypertensive patients with obstructive sleep apnoea not treated with continuous positive airway pressure. European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:2 Topics: Aged; Aged, 80 and over; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Continuous Positive Airway Pressure; Diastole; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Polysomnography; Reproducibility of Results; Sleep Apnea, Obstructive; Systole	2016
Replacement of Amlodipine and Lercanidipine by Barnidipine: Tolerability and Effectiveness in a Real-Life Study. High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2017, Volume: 24, Issue:1 Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Substitution; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Product Surveillance, Postmarketing; Prospective Studies; Time Factors; Treatment Outcome	2017
Pharmacokinetics of talinolol is modified by barnidipine: implication of P-glycoprotein modulation. Die Pharmazie, 2017, Jan-10, Volume: 72, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Interactions; Nifedipine; Propanolamines; Rats	2017
Computational drug repositioning for ischemic stroke: neuroprotective drug discovery. Future medicinal chemistry, 2021, Volume: 13, Issue:15 Topics: Algorithms; Animals; Apoptosis; Cell Line; Computational Biology; Dihydropyridines; Drug Discovery; Drug Repositioning; Humans; Ischemic Stroke; Mice; Neuroprotective Agents; Nifedipine; Oxidative Stress	2021
Exploring an experimental combination of analytical quality by design and green analytical chemistry approaches for development of HPTLC densitometric protocol for the analysis of barnidipine hydrochloride. Biomedical chromatography : BMC, 2022, Volume: 36, Issue:1 Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Green Chemistry Technology; Limit of Detection; Linear Models; Nifedipine; Reproducibility of Results; Research Design	2022