nifedipine and lacidipine

nifedipine has been researched along with lacidipine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.78)18.7374
1990's21 (58.33)18.2507
2000's7 (19.44)29.6817
2010's7 (19.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Reimão, JQ; Scotti, MT; Tempone, AG1
Sun, H1
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A1
Bron, S; Chambon, M; Colau, D; Majjigapu, SR; Michielin, O; Pilotte, L; Röhrig, UF; Turcatti, G; Van den Eynde, BJ; Vogel, P; Zoete, V1
Cosentino, M; Crema, A; D'Angelo, L; De Ponti, F; Einaudi, A; Frigo, GM1
Gambini, F; Gaviraghi, G; Micheli, D; Quartaroli, M; Tarter, G; Trist, DG1
Leonetti, G1
Arosio, E; Lechi, A; Montesi, G; Montresor, G; Sheiban, I; Tonni, S1
Arcaro, G; Arosio, E; Lechi, A; Montesi, G; Paluani, F; Pancera, P; Priante, F1
Pfaffendorf, M; Pijl, AJ; van Zwieten, PA1
Circo, A; D'Onofrio, V; Gulizia, M; Platania, F; Rizzini, P; Valenti, R1
Leonetti, G; Salvi, S1
Biasco, MG; Ciccone, M; Corriero, F; Di Michele, L; Di Noia, D; Rizzon, P1
Marchisio, M; Pascale, C; Santoro, A; Zampaglione, B1
Flammer, J; Lang, MG; Lüscher, TF; Meyer, P1
Mathy, MJ; Pfaffendorf, M; van Zwieten, PA1
Courseau, C; Garay, R; Giraud, F; Hannaert, P; Pallotta, M; Rota, R1
Elliott, HL1
Pfaffendorf, M; van Zwieten, PA2
Imai, S; Kawada, T; Nakazawa, M; Sun, HT1
Bachetti, T; Carboni, L; Ferri, S; Ratti, E; Spampinato, S; Van Amsterdam, FT1
Akopov, SE1
Dei Cas, L; Fappani, A; Metra, M; Nodari, S; Pelá, G; Raddino, R1
Aiello, M; Gambale, F; Moran, O; Pisciotta, M1
Adrián, MJ; Coca, A; Ribera, L; Sánchez, M; Sobrino, J; Torres, M1
Armas-Hernández, MJ; Armas-Padilla, MC; Carvajal, AR; Castillo-Moreno, A; Hernández-Hernández, R; Pacheco, B; Velasco, M1
Alcocer, L; Armas-Hernández, MJ; Armas-Padilla, MC; Hernández-Hernández, R; Lezama, E; Velasco, M1
Ansaloni, L; Bernabè, A; Gardini, G; Ghetti, R; Riccardi, R; Tranchino, RM1
Campagnola, M; Cominacini, L; Davoli, A; Fratta Pasini, A; Garbin, U; Lo Cascio, V; Nava, C; Pastorino, AM; Rossato, P1
Boffi, F; Congiu Castellano, A; Dell'Ariccia, M; Grande, S; Marzi, S; Rosi, A; Viti, V1
Cheng, G; Peng, W; Tang, J; Zhao, R; Zhu, R1
Damen, CW; González, O; Hankemeier, T; van der Kloet, FM; van Vliet, M; Vreeken, RJ1
Bisenieks, E; Duburs, G; Gall Troselj, K; Krauze, A; Poikans, J; Velena, A; Zarkovic, N1

Reviews

3 review(s) available for nifedipine and lacidipine

ArticleYear
Pharmacology of the dihydropyridine calcium antagonists: relationship between lipophilicity and pharmacodynamic responses.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:6

    Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Hemodynamics; Humans; Hypertension; In Vitro Techniques; Models, Biological; Nifedipine

1993
Similarities and differences between calcium antagonists: pharmacological aspects.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:1

    Topics: Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Humans; Hypertension; Nifedipine; Vasodilator Agents; Verapamil

1993
1,4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues-Model Compounds Targeting Oxidative Stress.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Amlodipine; Animals; Antioxidants; Azetidinecarboxylic Acid; Calcium Channel Blockers; Cattle; Dihydropyridines; Epithelial Cells; Humans; Hydrogen; Lipoproteins, LDL; Mice; Microsomes; Mitochondria; Niacinamide; Nifedipine; Nitrobenzenes; Oxidants; Oxidative Stress; Piperazines

2016

Trials

9 trial(s) available for nifedipine and lacidipine

ArticleYear
Comparative study of lacidipine and nifedipine SR in the treatment of hypertension: an Italian multicenter study. The Northern Italian Study Group of Lacidipine in Hypertension.
    Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 4

    Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Dihydropyridines; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Italy; Male; Middle Aged; Nifedipine

1991
Haemodynamic parameters in hypertensive patients: changes induced by lacidipine and nifedipine.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Randomized Controlled Trials as Topic; Time Factors

1989
Calcium antagonist antihypertensive treatment of non-insulin-dependent diabetics: efficacy and safety of lacidipine versus nifedipine SR.
    Journal of cardiovascular pharmacology, 1994, Volume: 23 Suppl 5

    Topics: Antihypertensive Agents; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Cholesterol; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Triglycerides

1994
A long-term study comparing lacidipine and nifedipine SR in hypertensive patients: safety data.
    Journal of cardiovascular pharmacology, 1994, Volume: 23 Suppl 5

    Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Dihydropyridines; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Single-Blind Method

1994
Effects of lacidipine and nifedipine on lower limb veins in nonphlebopathic patients.
    Journal of cardiovascular pharmacology, 1994, Volume: 23 Suppl 5

    Topics: Adult; Calcium Channel Blockers; Delayed-Action Preparations; Dihydropyridines; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Leg; Male; Middle Aged; Nifedipine; Regional Blood Flow; Ultrasonography, Doppler, Color; Veins

1994
The use of lacidipine in the management of hypertensive crises: a comparative study with nifedipine.
    Journal of cardiovascular pharmacology, 1994, Volume: 23 Suppl 5

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Emergency Medical Services; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine

1994
Long-acting lacidipine versus short-acting nifedipine in the treatment of asymptomatic acute blood pressure increase.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Diastole; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Reference Values; Single-Blind Method; Systole; Treatment Outcome

1999
Effect of lacidipine and nifedipine GITS on platelet function in patients with essential hypertension.
    Journal of human hypertension, 2000, Volume: 14 Suppl 1

    Topics: Arachidonic Acid; Biomarkers; Blood Platelets; Blood Pressure; Calcium Channels; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Malondialdehyde; Middle Aged; Nifedipine; Platelet Aggregation; Posture; Single-Blind Method

2000
Oral lacidipine in the treatment of anal fissure.
    Techniques in coloproctology, 2002, Volume: 6, Issue:2

    Topics: Administration, Oral; Adult; Aged; Calcium Channel Blockers; Dihydropyridines; Female; Fissure in Ano; Follow-Up Studies; Humans; Male; Middle Aged; Nifedipine; Pain; Pain Measurement; Prospective Studies; Time Factors

2002

Other Studies

24 other study(ies) available for nifedipine and lacidipine

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.
    Bioorganic & medicinal chemistry, 2010, Nov-15, Volume: 18, Issue:22

    Topics: Animals; Antiprotozoal Agents; Cell Line; Cricetinae; Dihydropyridines; Erythrocytes; Leishmania; Macaca mulatta; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2010
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction

2012
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
    Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity

2012
Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.
    European journal of medicinal chemistry, 2014, Sep-12, Volume: 84

    Topics: Animals; Antifungal Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Molecular Dynamics Simulation; Molecular Structure; Structure-Activity Relationship

2014
Effect of calcium channel blockers on postprandial gastrointestinal motility in the dog.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:3

    Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Eating; Electromyography; Female; Gastrointestinal Motility; Hemodynamics; Nifedipine

1992
The hemodynamic effects of lacidipine in anesthetized dogs: comparison with nitrendipine, amlodipine, verapamil, and diltiazem.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:3

    Topics: Amlodipine; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Stroke Volume; Vascular Resistance; Verapamil

1991
Remodeling of left ventricular geometry and function induced by lacidipine and nifedipine SR in mild-to-moderate hypertension.
    Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 4

    Topics: Adult; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Dihydropyridines; Heart Rate; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Models, Cardiovascular; Nifedipine; Ultrasonography; Ventricular Function, Left

1991
Hemodynamic and antiischemic effects of nifedipine, lacidipine, and nisoldipine in rat isolated working heart.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:3

    Topics: Animals; Calcium Channel Blockers; Cardiac Output; Coronary Circulation; Dihydropyridines; Dose-Response Relationship, Drug; Heart; Hemodynamics; In Vitro Techniques; Male; Mice; Myocardial Ischemia; Nifedipine; Nisoldipine; Rats; Rats, Wistar; Ventricular Function, Left

1993
Effects of calcium channel blockers on the response to endothelin-1, bradykinin and sodium nitroprusside in porcine ciliary arteries.
    Experimental eye research, 1995, Volume: 60, Issue:5

    Topics: Animals; Arteries; Bradykinin; Calcium Channel Blockers; Ciliary Body; Dihydropyridines; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; In Vitro Techniques; Nifedipine; Nitroprusside; Swine; Vasoconstriction

1995
In vitro effects of nifedipine, nisoldipine, and lacidipine on rat isolated coronary small arteries.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:3

    Topics: Animals; Calcium Channel Blockers; Coronary Vessels; Dihydropyridines; In Vitro Techniques; Male; Nifedipine; Nisoldipine; Potassium Chloride; Rats; Rats, Wistar; Serotonin Antagonists; Software; Vasoconstriction

1993
[Edema-inducing properties of lacidipine, nitrendipine and nifedipine in the spontaneously hypertensive rat].
    Archives des maladies du coeur et des vaisseaux, 1994, Volume: 87, Issue:8

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Edema; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR; Serum Albumin

1994
Vascular reactivity: a measurement of calcium channel blockade.
    Journal of human hypertension, 1995, Volume: 9 Suppl 1

    Topics: Amlodipine; Angiotensin II; Blood Pressure; Dihydropyridines; Humans; Infusions, Intravenous; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Vasoconstriction

1995
In vitro effects of the new calcium antagonist lacidipine.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:3

    Topics: Animals; Aorta; Calcium Channel Blockers; Carotid Arteries; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Papillary Muscles; Potassium

1993
Ca2+ channel blocking activity of lacidipine and amlodipine in A7r5 vascular smooth muscle cells.
    European journal of pharmacology, 1993, Jan-15, Volume: 244, Issue:2

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Cytosol; Dihydropyridines; Female; Fura-2; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium Chloride; Pregnancy; Rats; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1993
Nitric oxide (EDRF) enhances the vasorelaxing effect of dihydropyridine calcium antagonists in isolated human middle cerebral arteries.
    Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18, Issue:2

    Topics: Adult; Arginine; Calcium Channel Blockers; Cerebral Arteries; Cyclooxygenase Inhibitors; Dihydropyridines; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Humans; In Vitro Techniques; Indomethacin; Isradipine; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Vasodilator Agents

1996
Pharmacological activity of the new calcium antagonist, lacidipine, on isolated preparations.
    General pharmacology, 1996, Volume: 27, Issue:7

    Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Female; Heart; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Rabbits; Ventricular Pressure; Verapamil

1996
Interaction between dihydropyridines and phospholipid bilayers: a molecular dynamics simulation.
    European biophysics journal : EBJ, 1998, Volume: 27, Issue:3

    Topics: Calcium Channel Blockers; Dihydropyridines; Dimyristoylphosphatidylcholine; Lipid Bilayers; Models, Molecular; Molecular Conformation; Molecular Structure; Nifedipine; Phospholipids; Stimulation, Chemical; Thermodynamics

1998
Semipersonalized psychological evaluation of quality of life in hypertensive patients during a trial with two calcium antagonists: a multicenter Latin-American Study (LASTLHY).
    International journal of clinical pharmacology and therapeutics, 2001, Volume: 39, Issue:8

    Topics: Activities of Daily Living; Administration, Oral; Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Exercise; Female; Health Surveys; Humans; Hypertension; Male; Middle Aged; Nifedipine; Psychometrics; Quality of Life

2001
Antioxidant activity of different dihydropyridines.
    Biochemical and biophysical research communications, 2003, Mar-21, Volume: 302, Issue:4

    Topics: Amlodipine; Animals; Antioxidants; Cattle; Cells, Cultured; Dihydropyridines; Endothelium, Vascular; Fluoresceins; Humans; Lipoproteins, LDL; Molecular Structure; Nifedipine; Nimodipine; Reactive Oxygen Species

2003
MRS study of the interaction of dihydropyridines with lipid molecules in phosphatidylcholine vesicles.
    Physiological chemistry and physics and medical NMR, 2003, Volume: 35, Issue:1

    Topics: Dihydropyridines; Dimyristoylphosphatidylcholine; Lipid Metabolism; Lipids; Liposomes; Magnetic Resonance Spectroscopy; Molecular Structure; Nifedipine

2003
Ultra-performance liquid chromatography-tandem mass spectrometry for the determination of lacidipine in human plasma and its application in a pharmacokinetic study.
    Journal of pharmaceutical and biomedical analysis, 2008, Aug-05, Volume: 47, Issue:4-5

    Topics: Acetates; Administration, Oral; Buffers; Calcium Channel Blockers; Calibration; Chromatography, Liquid; Clinical Trials as Topic; Dihydropyridines; Drug Stability; Freezing; Humans; Hydrogen-Ion Concentration; Male; Methyl Ethers; Molecular Structure; Nifedipine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tablets; Tandem Mass Spectrometry

2008
Matrix Effect Compensation in Small-Molecule Profiling for an LC-TOF Platform Using Multicomponent Postcolumn Infusion.
    Analytical chemistry, 2015, Jun-16, Volume: 87, Issue:12

    Topics: Acetaminophen; Benzimidazoles; Benzoates; Biphenyl Compounds; Chromatography, High Pressure Liquid; Clomipramine; Dihydropyridines; Enkephalin, Leucine; Humans; Mass Spectrometry; Nifedipine; Pharmaceutical Preparations; Simvastatin; Telmisartan; Tetrazoles; Time Factors

2015