nifedipine has been researched along with isoproterenol in 196 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (42.35) | 18.7374 |
| 1990's | 79 (40.31) | 18.2507 |
| 2000's | 18 (9.18) | 29.6817 |
| 2010's | 15 (7.65) | 24.3611 |
| 2020's | 1 (0.51) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Riesner, K; Schäfer, HJ | 1 |
| Andersson, KE; Sjögren, C | 1 |
| Byon, YK; Fleckenstein, A; Fleckenstein-Grün, G; Haastert, HP; Späh, F | 1 |
| Hiwatari, M; Taira, N | 1 |
| Byon, KY; Fleckenstein, A; Grün, G | 1 |
| Alvarez, JL; Vassort, G | 2 |
| Inoue, Y; Ohya, Y; Sperelakis, N | 2 |
| Botella, A; Bueno, L; Delvaux, M; Frexinos, J | 1 |
| Dandona, P; Fonseca, V; Gill, J; Jeremy, JY | 1 |
| Chik, CL; Girard, M; Ho, AK; O'Brien, L | 1 |
| Hirano, Y; January, CT; Moscucci, A | 1 |
| Harbon, S; Khac, LD; Mokhtari, A; Renner, M | 1 |
| Kurtz, A; Scholz, H | 1 |
| Bishopric, NH; Sato, B; Webster, KA | 1 |
| Kennedy, RH; Ruch, S; Seifen, E | 1 |
| Abel, PW; Guyton, RA; Hatcher, CR; Jett, GK | 1 |
| Asskamp, B; Eckel, J; Reinauer, H | 1 |
| Aronson, JK; Brunotte, F; Green, Y; Radda, GK; Syme, PD | 1 |
| Mustafa, AA | 1 |
| Chiappe de Cingolani, G; Mattiazzi, A; Mundiña, C; Vittone, L | 2 |
| Bowling, N; Gengo, PJ; Hayes, JS; Kauffman, RF; Utterback, B; Wyss, VL | 1 |
| Dubyak, GR; Jones, SW; Marks, TN | 1 |
| Liepins, A; McWilliam, TM; Rankin, AJ | 1 |
| Clark, WA; Decker, RS; LaPres, JJ; Lesch, M; Rudnick, SJ | 1 |
| McLean, R; Pearl, RG; Prielipp, RC; Rosenthal, MH | 1 |
| Bois, P; Lenfant, J | 1 |
| Beck, IT; Dinda, PK; Prokopiw, I | 2 |
| Chen, NH; Rao, MR | 1 |
| Ohya, Y; Sperelakis, N | 1 |
| Docherty, JR | 1 |
| Clark, MG; Colquhoun, EQ; Hettiarachchi, M; Ye, JM | 1 |
| Auclair, MC; Lechat, P; Vernimmen, C | 1 |
| Bean, BP | 1 |
| Lazdunski, M; Renaud, JF; Schmid, A | 1 |
| Heisler, S | 1 |
| Hattori, Y; Hazama, S; Kanno, M; Nakao, Y | 1 |
| Lindemann, JP | 1 |
| Hess, P; Lansman, JB; Nilius, B; Tsien, RW | 1 |
| Mitra, R; Morad, M | 1 |
| Carriot, T; Doble, A; Dubroeucq, MC; Guérémy, C; Le Fur, G; Mestre, M; Néliat, G; Renault, C; Uzan, A | 1 |
| Bean, BP; Hess, P; Lansman, JB; Nilius, B; Nowycky, MC; Tsien, RW | 1 |
| Akera, T; Ng, YC; Temma, K | 1 |
| Hattori, Y; Kanno, M; Nakaya, H; Tohse, N | 1 |
| Ikeda, N; Kodama, I; Kubo, K; Toyama, J; Yamada, K; Yoshitake, I | 1 |
| Dietz, JR | 1 |
| Kim, D; Marsh, JD; Smith, TW | 1 |
| MacLeod, KM | 1 |
| Hui, KK; Yu, JL | 1 |
| Borst, S; Conolly, M | 1 |
| Briand, V; Laurent, S; Schmitt, H | 1 |
| Giuliani, S; Maggi, CA; Meli, A; Patacchini, R | 1 |
| Kondo, N | 2 |
| Baraka, A; Baroody, M; Haroun, S; Nawfal, M; Sibai, A | 1 |
| Fleckenstein, A; Fleckenstein-Grün, G; Frey, M; Zorn, J | 1 |
| Li, DM; Wang, XW; Zhang, KJ; Zhou, CM | 1 |
| Feller, DR; Hamada, A; Miller, DD; Patil, PN; Shams, G; Venkataraman, BV | 1 |
| Chung, M; Cohen, CJ; Thomas, G | 1 |
| Bkaily, G; Sperelakis, N | 1 |
| MacVicar, BA; Tse, FW | 1 |
| Malta, E; Molenaar, P | 1 |
| Carruthers, SG; Cordell, BA; McCall, B; Wu, R | 1 |
| Bright, DA; Falotico, R; Tobia, AJ | 1 |
| Milovanovic, SR; Prostran, M; Prostran, MS; Varagic, VM; Vasiljevic, Z | 1 |
| Bergman, B; Fredholm, BB; Lindström, K | 1 |
| Abdel-Rahman, AR; Ingenito, AJ | 1 |
| Fawzi, AB; McNeill, JH | 1 |
| Lockwood, TD | 1 |
| Agabiti-Rosei, E; Beschi, M; Castellano, M; Muiesan, G; Muiesan, ML; Romanelli, G | 1 |
| Klein, DC; Sugden, AL; Sugden, D | 1 |
| Chik, CL; Ho, AK; Klein, DC | 1 |
| Higaki, J; Nakamaru, M; Ogihara, T; Rakugi, H; Saito, H | 1 |
| Bolognesi, R; Manca, C; Poli, E; Raddino, R; Visioli, O | 1 |
| Bowling, N; Conery, BG; Hayes, JS; Kauffman, RF | 1 |
| Karasawa, A; Kubo, K; Nakamizo, N; Oka, T; Shuto, K | 1 |
| Jullien, T; Verdetti, J | 1 |
| Pearl, RG; Prielipp, RC; Rosenthal, MH | 1 |
| Bingham, WT; Duncan, WJ; Kasian, GF; Mersal, A; Ninan, A; Sankaran, K; Tyrrell, MJ | 1 |
| Drazen, JM; Fanta, CH; Lacouture, PG; Watson, JW | 1 |
| Eglème, C; Finet, M; Godfraind, T; Jaumin, P | 1 |
| Astolfi, M; Maggi, CA; Manzini, S; Meli, A; Parlani, M | 1 |
| Cortijo, J; Esplugues, J; Morcillo, EJ; Perpiñá, M | 1 |
| Daya, S; Joubert, PH | 1 |
| Antonipillai, I; Horton, R | 1 |
| Elguindi, AS; Smith, JK; Speir, WA | 1 |
| Jain, K; Kaur, AH; Singh, J; Singh, M | 1 |
| Aihara, H; Chiba, S; Kaneko, K; Tsuchida, K | 1 |
| Callanan, KM; Keenan, AK | 1 |
| Woodson, LC; Ziegler, MG | 1 |
| Hirata, Y; Kodama, I; Toyama, J; Yamada, K | 1 |
| Garay, A; Mattiazzi, AR | 1 |
| Sperelakis, N; Wahler, GM | 1 |
| Satoh, K; Taira, N; Wada, Y | 1 |
| Iurchenko, OP; Mukumov, MR; Sorokin, LV | 1 |
| Endoh, M; Taira, N; Yanagisawa, T | 1 |
| Horne, P; Triggle, DJ; Venter, JC | 1 |
| Delgado, C; Diez, J; Tamargo, J; Tejerina, MT | 1 |
| Greenway, CV; Seaman, KL | 1 |
| Corvol, P; Marre, M; Menard, J; Misumi, J; Raemsch, KD | 1 |
| Acconcia, MC; Gaspardone, A; Pannarale, G; Valente, A | 1 |
| Cacciapuoti, AA; Chiariello, M; Condorelli, M; de Alfieri, W; Genovese, A; Latte, S | 1 |
| Molyvdas, PA; Sperelakis, N | 1 |
| Joubert, P; Lowings, A; Sebata, B | 1 |
| Garay, A; Mattiazzi, A | 1 |
| Barbera, N; Carrozza, G; Ciraolo, O; Grosso, M; Lasco, A; Nicita-Mauro, V; Nicotina, PA; Squadrito, G | 1 |
| Himori, N; Taira, N | 1 |
| Drobinski, G; Grosgogeat, Y; Komajda, M; Thomas, D | 1 |
| Hattori, Y; Kanno, M; Nakaya, H; Nishihira, J | 1 |
| Kato, N | 1 |
| Ogihara, M | 1 |
| Archer, K; Buchheit, KH; Cook, SJ; Elliott, KR; Foster, RW; Fozard, JR; Martin, A; Miller, AJ; Müller, T; Small, RC | 1 |
| Ma, YX; Yu, S; Zhao, HY | 1 |
| Berweck, S; Clark, AF; Grássmann, A; Lepple-Wienhues, A; Rauch, R; Wiederholt, M | 1 |
| Andersen, LC; Clark, WA; LaPres, JJ; Rudnick, SJ | 1 |
| Alekseev, AE; Kokoz, YM; Korystova, AF; Mavlyutova, DA | 1 |
| Coetzee, A; Genade, S; Harper, I; Hattingh, P; Lochner, A | 1 |
| Borycz, J; Bugajski, AJ; Bugajski, J; Gadek-Michalska, A | 1 |
| Brooksby, P; Hancox, JC; Levi, AJ | 1 |
| Advenier, C; Brisac, AM; Cortijo, J; Laurent, S; Naline, E; Sarriá, B; Zhang, Y | 1 |
| Foot, EA; Leighton, B | 1 |
| Fukata, Y; Fukushima, H; Harada, K; Kaneta, S; Miwa, A; Ogawa, N | 1 |
| Miyata, N; Otomo, S; Takahashi, K; Tanaka, M; Tsuchida, K; Yamaura, H | 1 |
| Daniel, EE; Darby, PJ; Kwan, CY; Low, AM | 1 |
| Banitt, PF; Johnson, RG; Schoen, FJ; Sellke, FW; Shafique, T; Weintraub, RM | 1 |
| Ogata, M; Ohe, M; Shirato, K; Takishima, T | 1 |
| Liang, BT; Morley, JF | 1 |
| Alekseev, AE; Kokoz, YM; Korystova, AF; Markevich, NI; Terzic, A | 1 |
| Golod, DA; Goolsby, WN; Jongsma, HJ; Joyner, RW; Kumar, R; Van Ginneken, AC; Verheijck, EE; Wagner, MB; Wilders, R | 1 |
| Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K | 1 |
| Meera, P; Prakash, P; Tripathi, O | 1 |
| Elliott, J; Soydan, J | 1 |
| Altschuld, RA; Cannell, MB; Cheng, H; Gómez, AM; Lederer, MR; Lederer, WJ; McCune, SA; Santana, LF; Valdivia, HH | 1 |
| Fischmeister, R; Hoerter, J; Hove-Madsen, L; Legssyer, AK | 1 |
| Alekseev, AE; Kokoz, YM; Korystova, AF; Lankina, DA; Markevich, NI | 1 |
| Buus, C; Mulvany, MJ; Nilsson, H; Prieto, D | 1 |
| Taherzadeh, M; Warren, JB | 1 |
| Hussain, M; Orchard, CH | 1 |
| Vornanen, M | 1 |
| Huang, KL; Lin, YC | 1 |
| Higuchi, S; Nakasone, C; Noguchi, K; Shigenobu, K; Shijuku, T; Takahashi, K; Tanaka, H; Tanaka, Y | 1 |
| Honjo, H; Kodama, I; Satake, K; Shibata, S; Takagi, K; Toyama, J | 1 |
| Marczak, G; Wejman, I; Wiktorowska, A; Zalewska-Kaszubska, J | 1 |
| Bolle, P; Tucci, P | 1 |
| Hattori, Y; Houzen, H; Kanno, M; Yasuda, K; Yoshimoto, K | 1 |
| Boev, KK; Fusi, F; Petkov, GV; Sgaragli, GP; Valoti, M | 1 |
| Croxton, TL; Hirshman, CA; Lande, B; Lindeman, KS | 1 |
| Asano, M; Hazama, H; Imuta, H; Iwasawa, K; Kawakami, Y; Morita, T; Nakajima, T; Nakamura, F; Okuda, Y; Omata, M; Oonuma, H; Suzuki, J; Suzuki, S | 1 |
| Backx, PH; Bouchard, RA; Liu, PP; Oudit, GY; Tsushima, RG; Wickenden, AD | 1 |
| Bara, M; Guiet-Bara, A; Ibrahim, B; Leveteau, J | 1 |
| Herness, MS; Sun, XD | 1 |
| Janssen, LJ; Johri, AM | 1 |
| Milstone, DS; Mortensen, RM; Sowell, MO; Vassilev, PM; Ye, C | 1 |
| Lamorgese, M; McCarthy, PM; Nerbonne, JM; Pond, AL; Rossie, SS; Van Wagoner, DR | 1 |
| Aimond, F; Alvarez, JL; Lorente, P; Rauzier, JM; Vassort, G | 1 |
| Chemla, D; Coirault, C; Lecarpentier, Y; Pourny, JC; Sauviat, MP | 1 |
| Mahmoudian, M; Mirkhani, H; Omrani, GR; Shafiei, M | 1 |
| Chiu, P; Cook, SJ; Foster, RW; Isaac, L; Small, RC | 1 |
| Sekiguchi, F; Shimamura, K; Sunano, S; Yamamoto, K | 1 |
| Borbolla, JR; Collados, MT; López, S; Massó, FA; Montaño, LF; Páez, A; Sandoval, J | 1 |
| Coyne, MD; Gwathmey, JK; Kim, CS | 1 |
| Dalton, GR; Evans, SJ; Levi, AJ | 1 |
| Matsui, K; Ohashi, N; Sasabe, M; Yamamoto, S | 1 |
| Flameng, W; Macianskiene, R; Moccia, F; Mubagwa, K; Sipido, KR | 1 |
| Endoh, M; Han, X; Kubota, I; Sakurai, K; Tomoike, H | 1 |
| Balasubramaniam, R; Grace, AA; Huang, CL; Saumarez, RC; Vandenberg, JI | 1 |
| Balasubramaniam, R; Chawla, S; Grace, AA; Huang, CL; Mackenzie, L; Schwiening, CJ | 1 |
| Favaloro, JL; Kemp-Harper, BK | 1 |
| Comer, GR; Franchini, JL; Propst, JT; Yost, MJ | 1 |
| Donoso, P; Ferrero, P; Mattiazzi, A; Mundiña-Weilenmann, C; Said, M; Sánchez, G; Valverde, C; Vittone, L | 1 |
| Afeche, SC; Barbosa, R; Cipolla-Neto, J; Scialfa, JH; Simonneaux, V; Terra, IM | 1 |
| Chen, JN; John, SA; Ottolia, M; Philipson, KD; Xie, Y | 1 |
| Ramos, RF; Stamer, WD; Sumida, GM | 1 |
| Hälinen, M; Haverinen, J; Vornanen, M | 1 |
| Choudhury, P; El Mays, TY; Green, FH; Hollenberg, MD; Saifeddine, M | 1 |
| Adelmann, R; Bloch, W; Brockmeier, K; Emmelheinz, M; Haustein, M; Hescheler, J; Khalil, M; Matzkies, M; Nazzal, R; Nguemo, F; Pfannkuche, K; Pillekamp, F; Reppel, M; Rubenchyk, O | 1 |
| Joukar, F; Joukar, S; Sheibani, M | 1 |
| Harraz, OF; Welsh, DG | 1 |
| Feridooni, T; Hotchkiss, A; Pasumarthi, KB; Zhang, F | 1 |
| Dahlenborg, K; Kunze, A; Sartipy, P; Steel, D; Svedhem, S | 1 |
| Chen, X; Ghosh, A; Mukherjee, B; Yuan, Q | 1 |
| Bartels, P; Bian, JS; Foo, R; Galupo, MJ; Herzig, S; Hoppe, UC; Hu, Z; Huang, H; Jiang, F; Li, G; Liang, MC; Liao, P; Poh, KK; Ponniah, S; See, K; Soong, TW; Trasti, SL; Wang, J; Wong, YP; Yong, TF; Yu, CY; Yu, D; Zhang, G; Zhang, H | 1 |
| Acharya, A; Boeuf, H; Brungs, S; Hemmersbach, R; Hescheler, J; Lichterfeld, Y; Sachinidis, A | 1 |
| Choi, SW; Chung, HM; Jeong, YH; Jung, CR; Kim, CY; Kim, J; Kim, U; Lee, SG; Park, JH; Ryu, B | 1 |
5 review(s) available for nifedipine and isoproterenol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Fast Na+ channels and slow Ca2+ current in smooth muscle from pregnant rat uterus.
Topics: Adenosine; Animals; Calcium Channels; Female; Ion Channel Gating; Ion Channels; Isoproterenol; Magnesium; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardium; Nifedipine; Oxytocin; Pregnancy; Pregnancy, Animal; Rats; Saxitoxin; Sodium Channels; Uterus | 1992 |
Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium; Dihydropyridines; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Models, Biological; Nifedipine; Phosphorylation; Pyridines; Receptors, Adrenergic, beta | 1986 |
[Early pulmonary hypertension: current therapeutic prospectives].
Topics: Calcium Channel Blockers; Captopril; Diazoxide; Diltiazem; Humans; Hydralazine; Hypertension, Pulmonary; Isoproterenol; Nifedipine; Phentolamine; Time Factors | 1982 |
Experimental studies on myocardial stretch and ventricular arrhythmia in hypertrophied and non-hypertrophied hearts.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Death, Sudden, Cardiac; Dogs; Electrocardiography; Gadolinium; Heart; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Isoproterenol; Meta-Analysis as Topic; Models, Cardiovascular; Myocardial Contraction; Myocardium; Nifedipine; Ouabain; Quinolines; Randomized Controlled Trials as Topic; Rats; Rats, Inbred SHR; Rats, Wistar; Ryanodine; Thiadiazines; Vasodilator Agents | 2000 |
4 trial(s) available for nifedipine and isoproterenol
| Article | Year |
|---|---|
Lisinopril and nifedipine administration inhibits the ex vivo uptake of [45Ca2+] by platelets from hypertensive diabetic patients.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Platelets; Bucladesine; Calcium; Diabetes Complications; Diabetes Mellitus; Enalapril; Epinephrine; Female; Humans; Hypertension; Isoproterenol; Lisinopril; Male; Middle Aged; Nifedipine | 1992 |
Relationships between heart rate and PR interval during physiological and pharmacological interventions.
Topics: Adrenergic beta-Antagonists; Adult; Atrioventricular Node; Diltiazem; Electrocardiography; Female; Heart Rate; Humans; Isoproterenol; Male; Nifedipine; Physical Exertion; Receptors, Adrenergic, beta; Verapamil | 1987 |
Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia.
Topics: Albuterol; Bronchopulmonary Dysplasia; Child, Preschool; Diltiazem; Humans; Hydralazine; Hypertension, Pulmonary; Infant, Newborn; Isoproterenol; Male; Nifedipine; Oxygen Inhalation Therapy; Pulmonary Heart Disease | 1988 |
Characterization of von Willebrand factor in primary pulmonary hypertension.
Topics: Adrenergic beta-Agonists; Adult; Antigens; Biomarkers; Blotting, Western; Calcium Channel Blockers; Electrocardiography; Electrophoresis, Agar Gel; Endothelium, Vascular; Female; Humans; Hydralazine; Hypertension, Pulmonary; Infusions, Intra-Arterial; Isoproterenol; Male; N-Acetylneuraminic Acid; Nifedipine; Prognosis; Pulmonary Artery; Pulmonary Wedge Pressure; Vasodilation; Vasodilator Agents; von Willebrand Factor | 1999 |
187 other study(ies) available for nifedipine and isoproterenol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
[Calcium kinetics of myocardium in experimental hypercalcemia and isoproterenol lesions--ultrastructural and roentgen microanalytical findings].
Topics: Animals; Calcinosis; Calcium; Dihydrotachysterol; Etidronic Acid; Heart; Hypercalcemia; Isoproterenol; Myocardium; Nifedipine; Rats | 1978 |
Inhibition of ATP-induced contraction in the guinea-pig urinary bladder in vitro and in vivo.
Topics: Adenosine; Adenosine Triphosphate; Amines; Animals; Female; Guinea Pigs; Indomethacin; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Parasympatholytics; Propranolol; Tetrodotoxin; Theophylline; Urinary Bladder | 1979 |
[Comparative studies on the basic Ca2+ antagonistic activities of niludipine (Bay a 7168) and nifedipine (Bay a 1040) on the myocardium, myometrium and vessels of smooth muscles (author's transl)].
Topics: Action Potentials; Animals; Blood Vessels; Calcium; Cats; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Myometrium; Nifedipine; Papillary Muscles; Pyridines; Uterus | 1979 |
Antihypertensive effect of Niludipine (Bay a 7168) on conscious renal-hypertensive dogs.
Topics: Animals; Blood Pressure; Dogs; Drug Interactions; Female; Heart Rate; Hypertension, Renal; Isoproterenol; Male; Nifedipine; Propranolol; Pyridines; Time Factors; Vasodilator Agents | 1979 |
[The calcium-antagonistic fundamental effects of Verapamil on myocardial fibers and smooth muscle cells of the blood vessels].
Topics: Adenosine Triphosphate; Animals; Blood Vessels; Calcium; Guinea Pigs; Heart; Hemodynamics; Isoproterenol; Muscle Contraction; Muscle, Smooth; Myocardium; Nifedipine; Oxygen Consumption; Papillary Muscles; Prenylamine; Rabbits; Rats; Verapamil | 1975 |
Properties of the low threshold Ca current in single frog atrial cardiomyocytes. A comparison with the high threshold Ca current.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Function; Barium; Cadmium; Calcium; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Heart Atria; Isoproterenol; Nickel; Nifedipine; Ouabain; Phenylephrine; Propranolol; Rana catesbeiana | 1992 |
Intracellular pathways triggered by galanin to induce contraction of pig ileum smooth muscle cells.
Topics: Acetylcholine; Animals; Cell Communication; Colforsin; Dose-Response Relationship, Drug; Galanin; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Neuropeptides; Nifedipine; Peptides; Pertussis Toxin; Sincalide; Swine; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1992 |
Fast Na+ channels in smooth muscle from pregnant rat uterus.
Topics: Animals; Calcium Channels; Female; In Vitro Techniques; Isoproterenol; Magnesium; Muscle, Smooth, Vascular; Myometrium; Nifedipine; Oxytocin; Pregnancy; Pregnancy, Animal; Rats; Saxitoxin; Sodium Channels; Tetrodotoxin; Uterine Contraction; Uterus | 1992 |
Intracellular pH on protein kinase C and ionomycin potentiation of isoproterenol-stimulated cyclic AMP and cyclic GMP production in rat pinealocytes.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Cyclic AMP; Cyclic GMP; Hydrogen-Ion Concentration; Ionomycin; Isoproterenol; Male; Nifedipine; Phorbol Esters; Pineal Gland; Propionates; Protein Kinase C; Rats; Rats, Sprague-Dawley | 1992 |
Direct measurement of L-type Ca2+ window current in heart cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium Channels; Dogs; Isoproterenol; Membrane Potentials; Models, Biological; Nicardipine; Nifedipine; Purkinje Fibers | 1992 |
Activation of beta-adrenergic receptors inhibits Ca2+ entry-mediated generation of inositol phosphates in the guinea pig myometrium, a cyclic AMP-independent event.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aluminum; Animals; Calcium; Calcium Channels; Carbachol; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Drug Antagonism; Female; Fluorine; Guinea Pigs; Inositol Phosphates; Ionomycin; Isoproterenol; Myometrium; Nifedipine; Oxytocin; Pertussis Toxin; Receptors, Adrenergic, beta; Type C Phospholipases; Verapamil; Virulence Factors, Bordetella | 1992 |
Disparate effects of calcium channel blockers on pressure dependence of renin secretion and flow in the isolated perfused rat kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bumetanide; Calcium Channel Blockers; Glomerular Filtration Rate; In Vitro Techniques; Isoproterenol; Kidney; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Renin; Sodium; Verapamil | 1992 |
Beta-adrenergic regulation of a myocardial actin gene via a cyclic AMP-independent pathway.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Actins; Animals; Animals, Newborn; Blotting, Northern; Bucladesine; Caffeine; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Enkephalins; Gene Expression Regulation; Heart; Heart Ventricles; Isoproterenol; Kinetics; Myocardium; Nifedipine; Potassium Chloride; Propranolol; Protein Precursors; Rats; Receptors, Adrenergic, beta; RNA; RNA, Messenger; Ryanodine | 1992 |
Aging: inotropic effects of Bay K-8644 and nifedipine on rat cardiac muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Analysis of Variance; Animals; Calcium; Calcium Channels; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Rats; Rats, Inbred F344 | 1992 |
Inhibition of human internal mammary artery contractions. An in vitro study of vasodilators.
Topics: Adenosine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Isoproterenol; Mammary Arteries; Muscle Contraction; Nifedipine; Nitroglycerin; Nitroprusside; Norepinephrine; Potassium; Vasodilator Agents; Verapamil | 1992 |
Induction of insulin resistance in primary cultured adult cardiac myocytes.
Topics: Animals; Biological Transport; Bucladesine; Cells, Cultured; Cyclic AMP; Cycloheximide; Cytochalasin B; Deoxyglucose; Fatty Acids; Heart; Insulin; Insulin Resistance; Isoproterenol; Male; Myocardium; Nifedipine; Phenylalanine; Phosphorylation; Rats; Rats, Inbred Strains | 1991 |
The effect of beta 2-adrenoceptor stimulation and blockade of L-type calcium channels on in vivo Na+/H+ antiporter activity in rat skeletal muscle.
Topics: Adenosine Triphosphate; Amiloride; Animals; Calcium Channel Blockers; Calcium Channels; Carrier Proteins; Cytosol; Hydrogen-Ion Concentration; Isoproterenol; Lactates; Male; Muscle Contraction; Muscles; Nifedipine; Phosphates; Phosphocreatine; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Sodium-Hydrogen Exchangers | 1991 |
Rapid desensitization of central beta-adrenoceptors in rat after subacute treatment with imipramine and calcium entry blockers.
Topics: 1-Propanol; Animals; Calcium Channel Blockers; Clonidine; Diltiazem; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drinking Behavior; Fenclonine; Imipramine; Isoproterenol; Ketanserin; Nicardipine; Nifedipine; Oxidopamine; Rats; Receptors, Adrenergic, beta; Verapamil | 1991 |
cAMP and calcium-dependent mechanisms of phospholamban phosphorylation in intact hearts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphatases; Animals; Biomechanical Phenomena; Calcium; Calcium-Binding Proteins; Calmodulin; Cyclic AMP; In Vitro Techniques; Intracellular Membranes; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Osmolar Concentration; Phosphorylation; Rats; Rats, Inbred Strains | 1990 |
Cardiac inotropic responses to calcium and forskolin are not altered by prolonged isoproterenol infusion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Drug Interactions; Heart; In Vitro Techniques; Infusions, Intravenous; Isoproterenol; Kinetics; Myocardial Contraction; Myocardium; Nifedipine; Radioligand Assay; Rats; Receptors, Adrenergic, beta | 1990 |
Calcium currents in the A7r5 smooth muscle-derived cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Biological Transport; Calcium; Calcium Channels; Cell Line; Colforsin; Cytosol; Dihydropyridines; Electric Conductivity; Fluorescence; Isoproterenol; Ligands; Muscle, Smooth, Vascular; Nifedipine; Potassium | 1990 |
Deuterium oxide reduces agonist and depolarization-induced contraction of rat aortic rings.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Calcium; Deuterium; Deuterium Oxide; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Water | 1990 |
Hypertrophy of isolated adult feline heart cells following beta-adrenergic-induced beating.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cardiomegaly; Cats; Cells, Cultured; Colforsin; Culture Techniques; Cyclic AMP; Heart; Heart Rate; Isoproterenol; Myocardial Contraction; Myocardium; Myofibrils; Nifedipine; Norepinephrine; Propranolol; Receptors, Adrenergic, beta | 1991 |
Dual action of prajmalium on the Ca currents in frog isolated cardiomyocytes.
Topics: Animals; Calcium; Heart; Isoproterenol; Membrane Potentials; Myocardium; Nifedipine; Prajmaline; Prazosin; Propranolol; Rana catesbeiana; Rana esculenta; Sodium | 1991 |
Hemodynamic profiles of prostaglandin E1, isoproterenol, prostacyclin, and nifedipine in experimental porcine pulmonary hypertension.
Topics: Alprostadil; Animals; Blood Pressure; Cardiac Output; Epoprostenol; Heart Rate; Hemodynamics; Hypertension, Pulmonary; Isoproterenol; Nifedipine; Pulmonary Artery; Swine; Vascular Resistance; Vasodilator Agents | 1991 |
Evidence for two types of calcium currents in frog cardiac sinus venosus cells.
Topics: Animals; Barium; Biological Clocks; Biological Transport; Calcium; Cell Membrane; Cell Membrane Permeability; Cell Separation; Dose-Response Relationship, Drug; Electric Conductivity; Heart Ventricles; Isoproterenol; Membrane Potentials; Nifedipine; Rana esculenta; Ventricular Function | 1991 |
Comparison of vascular response of different locations of the gastrointestinal tract to isoproterenol and nifedipine.
Topics: Animals; Cardiac Output; Colon; Digestive System; Dogs; Heart Rate; Hemodynamics; Intestine, Small; Isoproterenol; Male; Microspheres; Nifedipine; Regional Blood Flow; Stomach | 1990 |
[Protecting effects of m-nifedipine on isoproterenol-induced myocardial injury in rats].
Topics: Animals; Calcium; Creatine Kinase; Hemodynamics; Isoproterenol; Magnesium; Male; Mitochondria, Heart; Myocardium; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Stereoisomerism | 1990 |
Tocolytic agents act on calcium channel current in single smooth muscle cells of pregnant rat uterus.
Topics: Animals; Calcium Channels; Electrophysiology; Evoked Potentials; Female; Isoproterenol; Magnesium; Muscle, Smooth; Nifedipine; Pregnancy; Rats; Tocolytic Agents; Uterus | 1990 |
Age-related differences in the depressor responses to sodium nitroprusside and nifedipine in anaesthetized rats.
Topics: Aging; Animals; Blood Pressure; Ferricyanides; Heart Rate; Isoproterenol; Male; Nifedipine; Nitroprusside; Rats; Rats, Inbred Strains | 1990 |
Flow-induced oxygen uptake by the perfused rat hindlimb is inhibited by vasodilators and augmented by norepinephrine: a possible role for the microvasculature in hindlimb thermogenesis.
Topics: Adenosine Triphosphate; Animals; Body Temperature Regulation; Electric Stimulation; Hindlimb; In Vitro Techniques; Isoproterenol; Lactates; Male; Microcirculation; Nifedipine; Nitroprusside; Norepinephrine; Oxygen Consumption; Perfusion; Phosphocreatine; Pyruvates; Rats; Rats, Inbred Strains; Vasodilator Agents | 1990 |
[Effect of substances modifying calcium movement on the contractility of cultured cardiac cells].
Topics: Animals; Caffeine; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Histamine; Imipramine; Ion Channels; Isoproterenol; Myocardial Contraction; Nifedipine; Phenylephrine; Rats; Verapamil | 1985 |
Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Barium; Calcium; Cobalt; Dogs; Heart Atria; Ion Channels; Isoproterenol; Kinetics; Myocardium; Nifedipine; Nitrendipine; Tetrodotoxin | 1985 |
Short term and long term effects of beta-adrenergic effectors and cyclic AMP on nitrendipine-sensitive voltage-dependent Ca2+ channels of skeletal muscle.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Alprenolol; Animals; Bucladesine; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Chick Embryo; Cyclic AMP; Ion Channels; Isoproterenol; Muscles; Nifedipine; Nitrendipine; Receptors, Nicotinic; Reserpine; Theophylline | 1985 |
BAY-K-8644-stimulated cyclic GMP synthesis in mouse pituitary tumor cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenocorticotropic Hormone; Animals; Azides; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Isoproterenol; Mice; Nifedipine; Nitroprusside; Pituitary Neoplasms; Sodium Azide; Stimulation, Chemical; Verapamil | 1986 |
Inotropic effects of Ca2+ channel agonist and antagonists in neuraminidase-treated left atria of rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Female; Heart Atria; In Vitro Techniques; Ion Channels; Isoproterenol; Male; Myocardial Contraction; N-Acetylneuraminic Acid; Neuraminidase; Nifedipine; Rats; Sialic Acids; Verapamil | 1986 |
Alpha-adrenergic stimulation of sarcolemmal protein phosphorylation and slow responses in intact myocardium.
Topics: Animals; Calcium; Calcium-Binding Proteins; Ion Channels; Isoproterenol; Kinetics; Male; Myocardial Contraction; Myocardium; Nifedipine; Phenylephrine; Phosphoproteins; Phosphorylation; Potassium; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sarcolemma; Sodium | 1986 |
A novel type of cardiac calcium channel in ventricular cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Colforsin; Electric Conductivity; Guinea Pigs; In Vitro Techniques; Ion Channels; Isoproterenol; Membrane Potentials; Nifedipine; Ventricular Function | 1986 |
Two types of calcium channels in guinea pig ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Diltiazem; Gallopamil; Guinea Pigs; Heart Ventricles; Ion Channels; Isoproterenol; Kinetics; Metals; Myocardium; Nifedipine | 1986 |
PK 11195, an antagonist of peripheral type benzodiazepine receptors, modulates Bay K8644 sensitive but not beta- or H2-receptor sensitive voltage operated calcium channels in the guinea pig heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Barium; Benzodiazepinones; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Isoproterenol; Isoquinolines; Male; Myocardial Contraction; Nifedipine; Papillary Muscles; Receptors, Adrenergic, beta; Receptors, GABA-A; Receptors, Histamine; Receptors, Histamine H2 | 1986 |
Effects of inotropic agents on isolated guinea pig heart under conditions that modify calcium pools involved in contractile activation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cardiotonic Agents; Diltiazem; Diterpenes; Female; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Monensin; Nifedipine; Ryanodine; Strophanthidin; Veratridine | 1986 |
Voltage-dependent effects of YC-170, a dihydropyridine calcium channel modulator, in cardiovascular tissues.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Cardiovascular System; Female; Guinea Pigs; Heart; Histamine; In Vitro Techniques; Ion Channels; Isoproterenol; Male; Muscle, Smooth; Nifedipine; Potassium; Rabbits; Sinoatrial Node; Tetraethylammonium Compounds | 1986 |
[Electrophysiological effects of KW-3049, a new dihydropyridine type Ca antagonist, on isolated rabbit hearts, sinus nodal tissues and guinea-pig ventricular muscles].
Topics: Animals; Bundle of His; Calcium Channel Blockers; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Ion Channels; Isoproterenol; Nifedipine; Papillary Muscles; Rabbits; Sinoatrial Node; Verapamil | 1986 |
Effects of a calcium channel agonist on renin release from perfused rat kidneys.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Ion Channels; Isoproterenol; Kidney; Male; Nifedipine; Perfusion; Rats; Rats, Inbred Strains; Renin; Verapamil | 1986 |
Effect of thyroid hormone on slow calcium channel function in cultured chick ventricular cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cell Division; Cells, Cultured; Chick Embryo; Heart; Ion Channels; Isoproterenol; Myocardial Contraction; Nifedipine; Receptors, Adrenergic, beta; Sarcolemma; Triiodothyronine; Ventricular Function | 1987 |
Adrenergic-cholinergic interactions in left atria. II. Comparison of the antagonism of inotropic responses to alpha- and beta-adrenoceptor stimulation and BAY K 8644 by carbachol, D-600, and nifedipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Chloride; Carbachol; Gallopamil; Isoproterenol; Myocardial Contraction; Nifedipine; Phenylephrine; Rabbits | 1987 |
The effects of calcium channel blockers on isoproterenol induced cyclic adenosine 3',5'-monophosphate generation in intact human lymphocytes.
Topics: 1-Methyl-3-isobutylxanthine; Calcium Channel Blockers; Cyclic AMP; Diltiazem; Drug Synergism; Humans; Isoproterenol; Kinetics; Lanthanum; Lymphocytes; Nifedipine; Phenothiazines; Verapamil | 1988 |
Calcium dependence of beta-adrenoceptor mediated cyclic AMP accumulation in human lymphocytes.
Topics: 1-Methyl-3-isobutylxanthine; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Edetic Acid; Humans; Isoproterenol; Kinetics; Lanthanum; Lymphocytes; Nifedipine; Receptors, Adrenergic, beta; Verapamil | 1988 |
Interaction between isoproterenol and dihydropyridines in heart cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cells, Cultured; Chick Embryo; Dihydropyridines; Heart; Isoproterenol; Myocardial Contraction; Myocardium; Nicardipine; Nifedipine; Time Factors | 1989 |
Potent contractile effect of endothelin in isolated guinea-pig airways.
Topics: Animals; Bronchi; Edetic Acid; Endothelins; Guinea Pigs; In Vitro Techniques; Indomethacin; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nifedipine; Peptides; Tetrodotoxin; Trachea | 1989 |
Effects of concanavalin A on cardiotonic responses to A23187 and isoprenaline.
Topics: Action Potentials; Animals; Calcimycin; Concanavalin A; Glycoside Hydrolases; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Lectins; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Methylmannosides; Myocardial Contraction; Myocardium; Nifedipine; Ryanodine | 1989 |
Voltage-dependence of ryanodine-sensitive component of contraction in A23187- and isoprenaline-treated cardiac muscles.
Topics: Alkaloids; Animals; Calcimycin; Calcium; Electric Stimulation; Female; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocardial Contraction; Nifedipine; Papillary Muscles; Ryanodine; Tetrodotoxin | 1989 |
Effects of preoperative calcium channel and beta-adrenergic blockade on the vascular response to adrenergic agonists during cardiopulmonary bypass.
Topics: Adult; Arteries; Blood Pressure; Blood Volume; Cardiopulmonary Bypass; Coronary Artery Bypass; Humans; Isoproterenol; Middle Aged; Nifedipine; Norepinephrine; Phenylephrine; Preoperative Care; Propranolol; Vascular Resistance; Veins | 1989 |
Amlodipine, a new 1,4-dihydropyridine calcium antagonist with a particularly strong antihypertensive profile.
Topics: Amlodipine; Animals; Antihypertensive Agents; Arteriosclerosis; Calcium; Calcium Channel Blockers; Dihydropyridines; Heart; In Vitro Techniques; Isoproterenol; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocardium; Nifedipine; Rabbits; Rats; Retinal Artery; Swine; Vasoconstriction | 1989 |
[Effects of 2[p-(dimethylamino)styryl]pyridine methiodide on action potentials of sinoatrial node cells of rabbits].
Topics: Action Potentials; Animals; Calcium Channel Blockers; Female; Humans; Isoproterenol; Male; Niacinamide; Nifedipine; Pyridinium Compounds; Rabbits; Sinoatrial Node | 1989 |
Paradoxical effects of isothiocyanate analog of tolazoline on rat aorta and human platelets.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Atrial Function; Benzazepines; Blood Platelets; Calcium; Carbachol; Dose-Response Relationship, Drug; Epinephrine; Female; Guinea Pigs; Heart Atria; Isoproterenol; Isothiocyanates; Male; Nifedipine; Phenoxybenzamine; Phentolamine; Phenylephrine; Platelet Activation; Platelet Aggregation; Prazosin; Rats; Rats, Inbred Strains; Temperature; Thiocyanates; Tolazoline; Trachea; Vasoconstriction; Verapamil; Yohimbine | 1989 |
A dihydropyridine (Bay k 8644) that enhances calcium currents in guinea pig and calf myocardial cells. A new type of positive inotropic agent.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Electric Stimulation; Female; Guinea Pigs; Ion Channels; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Nisoldipine; Nitrendipine; Purkinje Fibers; Stimulation, Chemical; Strontium; Time Factors | 1985 |
Injection of guanosine 5'-cyclic monophosphate into heart cells blocks calcium slow channels.
Topics: Action Potentials; Animals; Calcium; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic GMP; Electric Stimulation; Ion Channels; Isoproterenol; Myocardium; Nifedipine; Tetrodotoxin | 1985 |
Regional differences in the vascular response of the canine esophagus to vasodilators.
Topics: Animals; Dogs; Esophagogastric Junction; Esophagus; Hemodynamics; Isoproterenol; Male; Muscle, Smooth; Nifedipine; Regional Blood Flow; Vasodilation | 1989 |
Norepinephrine and cyclic adenosine 3':5'-cyclic monophosphate enhance a nifedipine-sensitive calcium current in cultured rat astrocytes.
Topics: Action Potentials; Animals; Astrocytes; Barium; Bucladesine; Calcium Channels; Cells, Cultured; Cerebral Cortex; Isoproterenol; Nifedipine; Norepinephrine; Rats | 1988 |
Analysis of agonist dissociation constants as assessed by functional antagonism in guinea pig left atria.
Topics: Adenosine; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzofurans; Carbachol; Catechols; Gallopamil; Guinea Pigs; Heart; In Vitro Techniques; Iodine Radioisotopes; Isoproterenol; Kinetics; Male; Myocardial Contraction; Nifedipine; Pindolol; Propanolamines | 1986 |
Evaluation of calcium entry blockers and alpha 2-adrenergic antagonists on B-HT 920-induced pressor responses in the autonomically blocked dog.
Topics: Adrenergic alpha-Agonists; Animals; Autonomic Nervous System; Azepines; Blood Pressure; Calcium Channel Blockers; Dimethylphenylpiperazinium Iodide; Dogs; Female; Gallopamil; Heart Rate; Isoproterenol; Male; Nifedipine; Yohimbine | 1987 |
[Comparative effects of dihydropyridine inhibitors of calcium penetration on spontaneous contraction of the isolated heart atria in the guinea pig].
Topics: Aminophylline; Animals; Atrial Function; Calcium; Calcium Chloride; Depression, Chemical; Drug Interactions; Female; Guinea Pigs; Isoproterenol; Male; Myocardial Contraction; Nicardipine; Nifedipine; Nitrendipine | 1988 |
Actions of enprofylline in the rat hippocampus.
Topics: Adenosine; Animals; Bronchodilator Agents; Cyclic AMP; Evoked Potentials; Felodipine; Hippocampus; Isoproterenol; Male; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Theophylline; Trifluoperazine; Xanthines | 1985 |
Similarities and differences in the effects of verapamil, diltiazem and nifedipine on arterial baroreflexes of anesthetized cats.
Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Carotid Arteries; Cats; Diltiazem; Electric Stimulation; Female; Heart Rate; Isoproterenol; Male; Nifedipine; Pressoreceptors; Receptors, Adrenergic, beta; Receptors, Muscarinic; Reflex; Vagotomy; Vagus Nerve; Verapamil | 1985 |
Effect of lanthanum on the inotropic response of isoproterenol: role of the superficially bound calcium.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cyclic AMP; Female; Guinea Pigs; Heart; Isoproterenol; Lanthanum; Male; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Receptors, Nicotinic | 1985 |
Simultaneous response of myocardial contractility and a major proteolytic process to beta-adrenergic-receptor occupancy in the Langendorff isolated perfused rat heart.
Topics: Animals; Cycloheximide; Heart; In Vitro Techniques; Isoproterenol; Leucine; Male; Muscle Proteins; Myocardial Contraction; Myocardium; Nifedipine; Perfusion; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1985 |
Adrenergic activity and left ventricular function during treatment of essential hypertension with calcium antagonists.
Topics: Adult; Blood Pressure; Epinephrine; Female; Heart; Heart Rate; Humans; Hypertension; Isoproterenol; Male; Middle Aged; Nifedipine; Norepinephrine; Receptors, Adrenergic, beta; Renin; Time Factors; Verapamil | 1986 |
Essential role of calcium influx in the adrenergic regulation of cAMP and cGMP in rat pinealocytes.
Topics: Animals; Calcimycin; Calcium; Cations; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Kinetics; Nifedipine; Norepinephrine; Ouabain; Pineal Gland; Rats; Rats, Inbred Strains | 1986 |
Protein kinase C is involved in adrenergic stimulation of pineal cGMP accumulation.
Topics: Animals; Calcimycin; Cyclic AMP; Cyclic GMP; Isoproterenol; Nifedipine; Ouabain; Pineal Gland; Potassium; Protein Kinase C; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1987 |
Endothelin inhibits renin release from isolated rat glomeruli.
Topics: Animals; Calcium; Endothelins; Isoproterenol; Kidney Glomerulus; Male; Nifedipine; Peptides; Rats; Rats, Inbred Strains; Renin | 1988 |
Effects of 17 beta-estradiol on the isolated rabbit heart.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vasospasm; Depression, Chemical; Estradiol; Female; Heart; Histamine; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nifedipine; Nitroglycerin; Propafenone; Propiophenones; Propranolol; Rabbits; Vascular Resistance; Vasopressins | 1986 |
Phosphorylation of ventricular sarcolemmal membranes does not alter binding properties of nitrendipine.
Topics: Alamethicin; Animals; Cats; Dihydropyridines; Dose-Response Relationship, Drug; Female; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Phosphorylation; Protein Kinases; Pyridines; Sarcolemma; Time Factors | 1985 |
[Correlation between myocardial relaxation and phosphorylation of phospholamban].
Topics: Animals; Calcium; Calcium-Binding Proteins; Isoproterenol; Myocardial Contraction; Nifedipine; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum | 1988 |
Antianginal effects of the new calcium antagonist benidipine hydrochloride in anesthetized rats and spontaneously hypertensive rats. Electrocardiographic study.
Topics: Angina Pectoris; Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Electrocardiography; Heart Rate; Hydralazine; Isoproterenol; Male; Nifedipine; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasopressins | 1988 |
Comparative electrophysiological response of young and old rat myocardium to pharmacological agents.
Topics: Action Potentials; Aging; Amiloride; Animals; Electric Stimulation; Female; Heart; Isoproterenol; Nifedipine; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds; Tetrodotoxin | 1988 |
Hemodynamic profiles of prostaglandin E1, isoproterenol, prostacyclin, and nifedipine in vasoconstrictor pulmonary hypertension in sheep.
Topics: Alprostadil; Animals; Drug Evaluation, Preclinical; Epoprostenol; Hemodynamics; Hypertension, Pulmonary; Isoproterenol; Lung; Nifedipine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Sheep; Vasodilation | 1988 |
In vivo bronchodilator activity of nifedipine in the guinea pig.
Topics: Airway Resistance; Animals; Bronchi; Bronchodilator Agents; Constriction, Pathologic; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethanol; Guinea Pigs; Histamine; Isoproterenol; Lung Compliance; Male; Nifedipine; Time Factors | 1987 |
The actions of nifedipine and nisoldipine on the contractile activity of human coronary arteries and human cardiac tissue in vitro.
Topics: Adolescent; Adult; Aged; Child; Coronary Vessels; Humans; In Vitro Techniques; Isoproterenol; Middle Aged; Myocardial Contraction; Nifedipine; Nisoldipine; Serotonin Antagonists; Vasoconstriction; Vasodilator Agents | 1987 |
Positive inotropic effect of Mg2+ in K+-depolarized isoprenaline-reactivated guinea-pig ventricular strip.
Topics: Action Potentials; Animals; Caffeine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kinetics; Magnesium; Myocardial Contraction; Nifedipine; Potassium; Stimulation, Chemical; Tetrodotoxin | 1986 |
Pharmacological characterization of the effects of verapamil and nifedipine on isolated guinea-pig lung parenchymal strip.
Topics: Acetylcholine; Animals; Calcium; Calcium Chloride; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Lung; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Potassium; Verapamil | 1986 |
The interaction between nifedipine and isoprenaline in isolated guinea-pig tracheal muscle precontracted with methacholine.
Topics: Animals; Drug Interactions; Guinea Pigs; In Vitro Techniques; Isoproterenol; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Nifedipine; Trachea | 1986 |
Role of extra- and intracellular calcium and calmodulin in renin release from rat kidney.
Topics: Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Calmodulin; Isoproterenol; Kidney Cortex; Kinetics; Male; Nifedipine; Rats; Rats, Inbred Strains; Renin | 1985 |
Facilitation of isoproterenol induced airway smooth muscle relaxation by nifedipine.
Topics: Animals; Drug Synergism; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Trachea | 1985 |
Effect of verapamil, nifedipine and diltiazem on experimental myocardial infarction in rats.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Female; Isoproterenol; Male; Myocardial Infarction; Nifedipine; Rats; Verapamil | 1985 |
Cardiovascular effects of an ionophorous antibiotic, lonomycin A, in anesthetized dogs.
Topics: Animals; Anti-Bacterial Agents; Coronary Circulation; Coronary Vessels; Dogs; Female; Ionophores; Isoproterenol; Male; Nifedipine; Nigericin; Ouabain; Papaverine; Pindolol; Potassium Chloride; Vasodilation | 1985 |
Differential effects of D600, nifedipine and dantrolene sodium on excitation-secretion coupling and presynaptic beta-adrenoceptor responses in rat atria.
Topics: Animals; Calcium; Calcium Channel Blockers; Dantrolene; Electric Stimulation; Female; Gallopamil; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Manganese; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Verapamil | 1984 |
Pressor response to beta-blocking drugs.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Female; Humans; Hypertension; Isoproterenol; Middle Aged; Nicardipine; Nifedipine; Norepinephrine; Pressoreceptors | 1984 |
Effects of niludipine (Bay-a-7168) on transmembrane action potentials of rabbit sinus node cells and atrial muscle fibers.
Topics: Action Potentials; Animals; Calcium; Heart; Heart Conduction System; In Vitro Techniques; Isoproterenol; Nifedipine; Pyridines; Rabbits | 1980 |
Negative inotropic effect of verapamil, nifedipine and prenylamine and its reversal by calcium or isoproterenol.
Topics: Animals; Calcium; Calcium Channel Blockers; Cats; In Vitro Techniques; Isoproterenol; Kinetics; Myocardial Contraction; Nifedipine; Papillary Muscles; Prenylamine; Verapamil | 1983 |
New Ca2+ agonist (Bay K 8644) enhances and induces cardiac slow action potentials.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Guinea Pigs; Heart; Ion Channels; Isoproterenol; Myocardial Contraction; Nifedipine; Papillary Muscles; Sodium; Stimulation, Chemical; Tetraethylammonium Compounds | 1984 |
Differential effects of Bay k 8644, a presumed calcium channel activator, on sinoatrial nodal and ventricular automaticity of the dog heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Dogs; Heart; Heart Rate; In Vitro Techniques; Ion Channels; Isoproterenol; Myocardial Contraction; Nifedipine; Papillary Muscles; Purkinje Fibers; Sinoatrial Node | 1984 |
[Effect of catecholamines on the electrical and mechanical activity of frog myocardium after increasing the duration of action potentials with nickel ions].
Topics: Action Potentials; Animals; Calcium; Catecholamines; Drug Interactions; Epinephrine; Heart; In Vitro Techniques; Ion Channels; Isoproterenol; Myocardial Contraction; Nickel; Nifedipine; Rana temporaria | 1980 |
Dissociation of cyclic AMP and contractile responses to isoprenaline: effects of a dihydropyridine derivative, nicardipine (YC-93), on canine ventricular muscle.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Calcium; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Female; Gallopamil; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nicardipine; Nifedipine; Papaverine; Pyridines; Theophylline; Vasodilator Agents | 1980 |
Nitrendipine and isoproterenol induce phosphorylation of a 42,000 dalton protein that co-migrates with the affinity labeled calcium channel regulatory subunit.
Topics: Affinity Labels; Animals; Cell Membrane; Dogs; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Ion Channels; Isoproterenol; Membrane Proteins; Myocardium; Nifedipine; Nitrendipine; Phosphorylation | 1984 |
Inotropic and electrophysiological effects of PY 108-068 on isolated cardiac preparations.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardial Contraction; Nifedipine; Papillary Muscles; Rats; Verapamil | 1984 |
Hepatic venoconstrictor effects of isoproterenol and nifedipine in anesthetized cats.
Topics: Adrenalectomy; Anesthesia; Animals; Blood Pressure; Cats; Denervation; Hepatic Veins; Isoproterenol; Nephrectomy; Nifedipine; Vasoconstrictor Agents | 1984 |
Diuretic and natriuretic effects of nifedipine on isolated perfused rat kidneys.
Topics: Animals; Dihydralazine; Diuretics; In Vitro Techniques; Isoproterenol; Kidney; Male; Natriuresis; Nifedipine; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Renin | 1982 |
Effects of antiplatelet and calcium antagonist drugs on infarct size in rats.
Topics: Acute Disease; Animals; Aspirin; Blood Platelets; Calcium; Creatine Kinase; Isoproterenol; Lysine; Male; Myocardial Infarction; Nifedipine; Platelet Aggregation; Rats; Verapamil | 1980 |
Comparison of the effects of several calcium antagonistic drugs on the electrical activity of guinea pig Purkinje fibers.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Electrophysiology; Female; Guinea Pigs; Heart Conduction System; Histamine; Isoproterenol; Male; Nifedipine; Purkinje Fibers; Verapamil | 1983 |
Bronchodilator potential of nifedipine in vitro.
Topics: Animals; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Histamine Antagonists; Isoproterenol; Muscle Contraction; Nifedipine; Pyridines; Trachea | 1982 |
Decrease in time to peak tension produced by calcium blockers and isoproterenol. Its dependence on extracellular calcium.
Topics: Animals; Blood Pressure; Calcium; Cats; Dose-Response Relationship, Drug; Isoproterenol; Myocardial Contraction; Nifedipine; Verapamil | 1982 |
[Effect of nifedipine on experimental myocardial infarct induced by isoproterenol].
Topics: Animals; Isoproterenol; Myocardial Infarction; Nifedipine; Pyridines; Rats; Rats, Inbred Strains | 1981 |
Differential effects of the calcium-antagonistic vasodilators, nifedipine and verapamil, on the tracheal musculature and vasculature of the dog.
Topics: Animals; Dogs; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyridines; Regional Blood Flow; Trachea; Verapamil | 1980 |
[Primary pulmonary arterial hypertension. Trial treatment with nifedipine, diazoxide and isoproterenol].
Topics: Diazoxide; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmonary; Isoproterenol; Middle Aged; Nifedipine; Pyridines | 1980 |
A dual-component positive inotropic effect of endothelin-1 in guinea pig left atria: a role of protein kinase C.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Function; Atrial Function, Left; Cardiotonic Agents; Electrophysiology; Endothelins; Enzyme Activation; Female; Guinea Pigs; Heart; Heart Atria; Hydrolysis; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Phosphatidylinositols; Protein Kinase C; Ryanodine; Signal Transduction | 1993 |
Mechanisms of beta-adrenergic facilitation of LTP in rat visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channels; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Neurons; Nifedipine; Rats; Receptors, N-Methyl-D-Aspartate; Visual Cortex | 1993 |
Potentiation of isoproterenol-stimulated gluconeogenesis in serum-free cultures of rat hepatocytes by nifedipine and nicardipine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Channel Blockers; Cells, Cultured; Culture Media, Serum-Free; Cyclic AMP; Drug Synergism; Gluconeogenesis; Isoproterenol; Lactates; Lactic Acid; Liver; Male; Nicardipine; Nifedipine; Rats; Rats, Wistar | 1993 |
Further analysis of the mechanisms underlying the tracheal relaxant action of SCA40.
Topics: Animals; Cyclic AMP; Electric Stimulation; Electrophysiology; Female; Guinea Pigs; Imidazoles; Isoproterenol; Male; Nifedipine; Parasympatholytics; Pyrazines; Quinine; Theophylline; Trachea | 1995 |
Effects of isoprenaline, phenylephrine on heart and influence of nifedipine on these effects.
Topics: Animals; Calcium Channels; Female; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nifedipine; Phenylephrine; Rats; Rats, Sprague-Dawley | 1994 |
Electrophysiological properties of cultured human trabecular meshwork cells.
Topics: Acetylcholine; Action Potentials; Cells, Cultured; Endothelins; Humans; Isoproterenol; Membrane Potentials; Metipranolol; Nifedipine; Tetrodotoxin; Trabecular Meshwork | 1994 |
Myosin heavy chain synthesis is independently regulated in hypertrophy and atrophy of isolated adult cardiac myocytes.
Topics: Actins; Animals; Atrophy; Calcium Channels; Cats; Cells, Cultured; Desmin; Gene Expression Regulation; Hypertrophy; Isoproterenol; Muscle Contraction; Myocardium; Myofibrils; Myosins; Nifedipine; Phenylephrine | 1994 |
Potential-dependent Ca2+ currents in isolated heart cells of hibernators.
Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Colforsin; Electric Conductivity; Electrophysiology; Gallopamil; Heart; Hibernation; Isoproterenol; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Sciuridae | 1994 |
Effects of beta-blockers and Ca(2+)-antagonists on the response of the isolated working rat heart to adrenergic stimulants after cardioplegic arrest.
Topics: Adenine Nucleotides; Animals; Cardiac Output; Cardiotonic Agents; Disease Models, Animal; Dobutamine; Epinephrine; Heart; Heart Arrest, Induced; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Reperfusion; Myocardium; Nifedipine; Propranolol; Rats; Rats, Wistar; Stimulation, Chemical | 1993 |
Calcium channel blockers impair the pituitary-adrenocortical responses to central adrenergic receptors stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Clonidine; Corticosterone; Drug Interactions; Hypothalamo-Hypophyseal System; Isoproterenol; Male; Nifedipine; Phenylephrine; Pituitary-Adrenal System; Rats; Rats, Wistar; Stimulation, Chemical; Verapamil | 1993 |
Intracellular calcium transients recorded with Fura-2 in spontaneously active myocytes isolated from the atrioventricular node of the rabbit heart.
Topics: Action Potentials; Animals; Atrioventricular Node; Calcium; Calcium Channels; Cells, Cultured; Fura-2; Isoproterenol; Kinetics; Male; Membrane Potentials; Myocardium; Nifedipine; Rabbits; Ryanodine; Sarcoplasmic Reticulum; Sodium; Spectrometry, Fluorescence; Time Factors | 1994 |
The nicardipine-isoprenaline interaction in human and guinea-pig isolated airways.
Topics: Adenosine; Animals; Bronchi; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Humans; Isoproterenol; Male; Muscle Relaxation; Nicardipine; Nifedipine; Nitroprusside; Theophylline; Trachea | 1994 |
Effects of calcium antagonists on insulin-mediated glucose metabolism in skeletal muscle.
Topics: Animals; Calcium Channel Blockers; Carbon Radioisotopes; Cyclic AMP; Diltiazem; Dose-Response Relationship, Drug; Glucose; Glycogen; Glycolysis; In Vitro Techniques; Insulin; Isoproterenol; Kinetics; Lactates; Male; Muscles; Nifedipine; Rats; Rats, Wistar; Verapamil | 1994 |
Effect of KRN2391, a novel vasodilator, on various experimental anginal models in rats.
Topics: Angina Pectoris; Animals; Disease Models, Animal; Electrocardiography; Injections, Intravenous; Isoproterenol; Male; Methacholine Chloride; Niacinamide; Nicorandil; Nifedipine; Pyridines; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
CD-832, a new dihydropyridine derivative with both nitrate-like and Ca2+ channel antagonist vasodilator activities.
Topics: Animals; Aorta, Thoracic; Brain Chemistry; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nifedipine; Nitrates; Rabbits; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
Effects of thapsigargin and ryanodine on vascular contractility: cross-talk between sarcoplasmic reticulum and plasmalemma.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium-Transporting ATPases; Cell Communication; Cell Membrane; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum; Sodium; Temperature; Terpenes; Thapsigargin | 1993 |
Relaxation responses of the coronary microcirculation after cardiopulmonary bypass and ischemic arrest with cardioplegia: implications for the treatment of postoperative coronary spasm.
Topics: Animals; Blood; Blood Pressure; Cardioplegic Solutions; Cardiopulmonary Bypass; Coronary Vasospasm; Coronary Vessels; Heart Arrest, Induced; Hypertonic Solutions; Isoproterenol; Microcirculation; Myocardial Reperfusion; Nifedipine; Nitroglycerin; Nitroprusside; Postoperative Complications; Potassium; Potassium Compounds; Swine; Vasodilation | 1993 |
Effects of a combination therapy of anticoagulant and vasodilator on the long-term prognosis of primary pulmonary hypertension.
Topics: Adolescent; Adult; Drug Combinations; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Isoproterenol; Male; Middle Aged; Nifedipine; Prognosis; Survival Rate; Warfarin | 1993 |
A new cyclic AMP-independent, Gs-mediated stimulatory mechanism via the adenosine A2a receptor in the intact cardiac cell.
Topics: Adenosine; Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Chick Embryo; Cyclic AMP; GTP-Binding Proteins; Ion Transport; Isoproterenol; Myocardial Contraction; Myocardium; Nifedipine; Phenethylamines; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Verapamil | 1996 |
Comparative analysis of the kinetic characteristics of L-type calcium channels in cardiac cells of hibernators.
Topics: Animals; Biophysical Phenomena; Biophysics; Calcium Channel Blockers; Calcium Channels; Hibernation; In Vitro Techniques; Ion Channel Gating; Isoproterenol; Kinetics; Membrane Potentials; Models, Biological; Myocardium; Nifedipine; Sciuridae | 1996 |
Modulating L-type calcium current affects discontinuous cardiac action potential conduction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adrenergic beta-Agonists; Animals; Biophysical Phenomena; Biophysics; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Electric Conductivity; Electric Stimulation; Guinea Pigs; Heart Ventricles; Isoproterenol; Models, Cardiovascular; Myocardium; Nifedipine | 1996 |
Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis.
Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Female; Heart Rate; Isoproterenol; Male; Myocardial Ischemia; Niacinamide; Nifedipine | 1996 |
Effects of calcium channel blockers on spontaneous electrical activity of freshly isolated three-day-old embryonic chick ventricle.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Chick Embryo; Diltiazem; Dose-Response Relationship, Drug; Fendiline; Heart Ventricles; In Vitro Techniques; Isoproterenol; Nifedipine; Regression Analysis; Tetrodotoxin; Ventricular Function; Verapamil | 1996 |
Characterisation of beta-adrenoceptors in equine digital veins: implications of the modes of vasodilatory action of isoxsuprine.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Azepines; Blood Vessels; Dose-Response Relationship, Drug; Fenoterol; Horses; Isoproterenol; Isoxsuprine; Methoxamine; Nifedipine; Norepinephrine; Phenylephrine; Propanolamines; Receptors, Adrenergic, beta; Vasoconstriction; Vasodilation; Veins | 1995 |
Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cardiomegaly; Cell Membrane; Heart Failure; Hypertension; Isoproterenol; Microscopy, Confocal; Muscle Proteins; Myocardial Contraction; Myocardium; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Inbred Strains; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum | 1997 |
Sympathetic modulation of the effect of nifedipine on myocardial contraction and Ca current in the rat.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Heart Ventricles; Hypertension; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardial Reperfusion; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Sympatholytics; Sympathomimetics; Ventricular Function | 1997 |
The kinetic characteristics of the L-type calcium channels in cardiocytes of hibernators. 1. Development of a kinetic model.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cardiotonic Agents; Cells, Cultured; Electric Conductivity; Heart; Hibernation; Isoproterenol; Kinetics; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Sciuridae | 1997 |
Interactions between neuropeptide Y and the adenylate cyclase pathway in rat mesenteric small arteries: role of membrane potential.
Topics: 4-Aminopyridine; Acetylcholine; Adenylyl Cyclases; Animals; Charybdotoxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dichlororibofuranosylbenzimidazole; Gadolinium; Glyburide; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Neuropeptide Y; Nifedipine; Potassium Channels; Rats; Rats, Wistar; Thionucleotides | 1997 |
Cardiac inotropes inhibit the oedema caused by nifedipine in rabbit skin.
Topics: Animals; Bradykinin; Calcium Channel Blockers; Cardiotonic Agents; Dinoprostone; Dobutamine; Dopamine; Edema; Histamine; Isoproterenol; Male; Microcirculation; Nifedipine; Rabbits; Skin | 1997 |
Sarcoplasmic reticulum Ca2+ content, L-type Ca2+ current and the Ca2+ transient in rat myocytes during beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Animals; Caffeine; Calcium; Calcium Channels; Calcium Channels, L-Type; Calcium-Transporting ATPases; Cells, Cultured; Heart; Isoproterenol; Kinetics; Male; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum; Thapsigargin | 1997 |
L-type Ca2+ current in fish cardiac myocytes: effects of thermal acclimation and beta-adrenergic stimulation.
Topics: Acclimatization; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Barium; Caffeine; Calcium; Carps; Colforsin; Heart; In Vitro Techniques; Ion Channel Gating; Isoproterenol; Membrane Potentials; Microscopy, Electron; Nifedipine; Oncorhynchus mykiss; Sarcolemma; Species Specificity; Temperature | 1998 |
Pharmacologic modulation of pulmonary vascular permeability during air embolism.
Topics: Animals; Capillary Permeability; Cyclooxygenase Inhibitors; Hypertension, Pulmonary; Indomethacin; Isoproterenol; Lung; Male; Nifedipine; Pulmonary Artery; Pulmonary Embolism; Rats; Rats, Wistar; Vascular Resistance | 1997 |
Possible involvement of nitric oxide-cGMP pathway in the negative chronotropic effect of CD-832, a novel dihydropyridine derivative.
Topics: Animals; Calcium Channel Blockers; Cyclic GMP; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Molsidomine; Niacinamide; Nifedipine; Nitric Oxide | 1998 |
Relaxant effects of NKH477, a new water-soluble forskolin derivative, on guinea-pig tracheal smooth muscle: the role of Ca2+-activated K+ channels.
Topics: Animals; Bronchodilator Agents; Calcium; Colforsin; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Peptides; Potassium; Potassium Channels; Solubility; Trachea; Water | 1998 |
The responsiveness of the endogenous inhibitor of cAMP-dependent protein kinase to isoproterenol after prolonged treatment with nifedipine.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Frontal Lobe; Hippocampus; Intercellular Signaling Peptides and Proteins; Isoproterenol; Male; Nifedipine; Peptides; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Stimulation, Chemical | 1998 |
Response to isoproterenol of rabbit detrusor strips following exposure to NSAIDs.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; In Vitro Techniques; Isoproterenol; Male; Nifedipine; Potassium Chloride; Rabbits; Receptors, Adrenergic, beta; Urinary Bladder | 1998 |
Histamine H1-receptor-mediated increase in the Ca2+ transient without a change in the Ca2+ current in electrically stimulated guinea-pig atrial myocytes.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Atrial Function; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Electric Stimulation; Female; Guinea Pigs; Heart; Heart Atria; Histamine; Histamine Antagonists; In Vitro Techniques; Isoproterenol; Male; Myocardium; Nifedipine; Patch-Clamp Techniques; Receptors, Histamine H1 | 1998 |
Myorelaxant activity of 2-t-butyl-4-methoxyphenol (BHA) in guinea pig gastric fundus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Antihypertensive Agents; Antioxidants; Barium; Butylated Hydroxyanisole; Calcium Channel Agonists; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Indoles; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Nifedipine; Nitroprusside; Tetraethylammonium; Vasodilator Agents | 1998 |
Hypocapnia-induced contraction of porcine airway smooth muscle.
Topics: Animals; Bronchi; Bronchodilator Agents; Calcium; Calcium Channel Blockers; Carbachol; Carbon Dioxide; Hydrogen-Ion Concentration; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nifedipine; Swine; Trachea | 1998 |
Troglitazone inhibits voltage-dependent calcium currents in guinea pig cardiac myocytes.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, T-Type; Cardiotonic Agents; Chromans; Cyclic AMP; Electric Conductivity; Guinea Pigs; Hypoglycemic Agents; Isoproterenol; Kinetics; Myocardium; Nifedipine; Thiazoles; Thiazolidinediones; Troglitazone; Verapamil | 1999 |
Modulation of iron uptake in heart by L-type Ca2+ channel modifiers: possible implications in iron overload.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Heart; In Vitro Techniques; Iron; Isoproterenol; Male; Myocardium; Nifedipine; Patch-Clamp Techniques; Permeability; Rats; Rats, Sprague-Dawley | 1999 |
Calcium channels, potassium channels and membrane potential of smooth muscle cells of human allantochorial placental vessels.
Topics: Acetylcholine; Adrenergic beta-Agonists; Allantois; Calcium Channel Blockers; Calcium Channels; Chorion; Humans; In Vitro Techniques; Isoproterenol; Membrane Potentials; Muscle, Smooth; Nifedipine; Nitric Oxide Donors; Nitroprusside; Placenta; Potassium Channels; Serotonin | 1999 |
Characterization of chloride currents and their noradrenergic modulation in rat taste receptor cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adrenergic beta-Agonists; Animals; Cadmium; Chloride Channels; In Vitro Techniques; Isoproterenol; Membrane Potentials; Nifedipine; Niflumic Acid; Patch-Clamp Techniques; Propranolol; Rats; Taste; Taste Buds | 1999 |
N-Type Ca(2+) channels trigger release of excitatory and inhibitory neurotransmitter from nerve endings in canine bronchi.
Topics: Acetylcholine; Agatoxins; Animals; Bronchi; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Dogs; Electric Stimulation; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Nerve Endings; Neurotransmitter Agents; Nifedipine; Norepinephrine; omega-Conotoxin GVIA; Peptides; Potassium Chloride; Spider Venoms | 1999 |
Galpha(i2), Galpha(i3)and Galpha(o) are all required for normal muscarinic inhibition of the cardiac calcium channels in nodal/atrial-like cultured cardiocytes.
Topics: Action Potentials; Animals; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cell Line; GTP-Binding Proteins; Heart; Heart Ventricles; Isoproterenol; Mice; Models, Cardiovascular; Molsidomine; Muscarinic Antagonists; Myocardium; Nifedipine; Nitric Oxide Donors; omega-N-Methylarginine; Pertussis Toxin; Receptors, Muscarinic; Stem Cells; Virulence Factors, Bordetella | 1999 |
Atrial L-type Ca2+ currents and human atrial fibrillation.
Topics: Action Potentials; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Chronic Disease; Coronary Artery Bypass; Disease Susceptibility; Female; Gene Expression Regulation; Heart Atria; Heart Conduction System; Heart Transplantation; Heart Valve Prosthesis Implantation; Humans; Ion Channel Gating; Ion Transport; Isoproterenol; Male; Middle Aged; Muscle Proteins; Myocardial Contraction; Nifedipine; Patch-Clamp Techniques; Postoperative Complications | 1999 |
Ionic basis of ventricular arrhythmias in remodeled rat heart during long-term myocardial infarction.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Arrhythmias, Cardiac; Biological Transport, Active; Blotting, Western; Calcium Channel Blockers; Calcium Channels; Gene Expression; Ion Transport; Isoproterenol; Male; Methoxamine; Myocardial Infarction; Nifedipine; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Wistar; Time Factors; Ventricular Remodeling | 1999 |
The effects of gadolinium, a stretch-sensitive channel blocker, on diaphragm muscle.
Topics: Action Potentials; Adenosine Monophosphate; Adenylyl Cyclases; Analysis of Variance; Animals; Colforsin; Cricetinae; Culture Techniques; Diaphragm; Dose-Response Relationship, Drug; Enzyme Activation; Evoked Potentials; Gadolinium; Ion Channels; Isometric Contraction; Isoproterenol; Mesocricetus; Muscle Fibers, Skeletal; Nifedipine; Patch-Clamp Techniques | 1999 |
Effects of different vasodilators on human internal mammary artery in vitro.
Topics: Ethanolamines; Female; Humans; In Vitro Techniques; Isoproterenol; Isosorbide Dinitrate; Male; Mammary Arteries; Middle Aged; Myocardial Ischemia; Nifedipine; Phenylephrine; Potassium Chloride; Propranolol; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Beta-adrenoceptor agonists in bronchial asthma: role of k+-channel opening in mediating their bronchodilator effects.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Albuterol; Animals; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cell Membrane; Charybdotoxin; Guinea Pigs; Humans; Ion Transport; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Nifedipine; Peptides; Potassium; Potassium Channels; Procaterol; Terbutaline | 1993 |
Altered beta-adrenoceptor-mediated responses in the gastric smooth muscle of hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Colforsin; Electrophysiology; Gastric Emptying; Gastric Fundus; Gastric Mucosa; Hypertension; Isoproterenol; Male; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta | 2000 |
Voltage-dependent calcium channels in ventricular cells of rainbow trout: effect of temperature changes in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adaptation, Physiological; Animals; Barium; Body Temperature; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiotonic Agents; Cold Temperature; Colforsin; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Isoproterenol; Membrane Potentials; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Nifedipine; Oncorhynchus mykiss; Patch-Clamp Techniques; Pyrroles; Tetrodotoxin | 2000 |
Effect of an orally active Na+/H+ exchange inhibitor, SMP-300, on experimental angina and myocardial infarction models in rats.
Topics: Administration, Oral; Angina Pectoris; Animals; Azocines; Coronary Disease; Electrocardiography; Isoproterenol; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nicorandil; Nifedipine; Propranolol; Pyrroles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium-Hydrogen Exchangers; Vasodilator Agents; Vasopressins | 2002 |
Channels involved in transient currents unmasked by removal of extracellular calcium in cardiac cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cesium; Chelating Agents; Diltiazem; Drug Resistance; Egtazic Acid; Electric Conductivity; Heart Ventricles; Isoproterenol; Kinetics; Magnesium; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Receptors, Adrenergic, beta; Swine; Verapamil | 2002 |
The Na+-Ca2+ exchanger contributes to beta-adrenoceptor mediated positive inotropy in mouse heart.
Topics: Animals; Calcium Channel Blockers; Cardiotonic Agents; Cells, Cultured; Isoproterenol; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardium; Nifedipine; Receptors, Adrenergic, beta; Sodium-Calcium Exchanger; Stimulation, Chemical; Verapamil | 2002 |
Electrogram prolongation and nifedipine-suppressible ventricular arrhythmias in mice following targeted disruption of KCNE1.
Topics: Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiac Pacing, Artificial; Electric Stimulation; Electrocardiography; Electrodes, Implanted; Electrophysiology; In Vitro Techniques; Isoproterenol; Mice; Mice, Knockout; Nifedipine; Patch-Clamp Techniques; Phenotype; Potassium Channels; Potassium Channels, Voltage-Gated | 2003 |
Nifedipine and diltiazem suppress ventricular arrhythmogenesis and calcium release in mouse hearts.
Topics: Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channel Blockers; Cytosol; Diltiazem; Electric Stimulation; Heart; In Vitro Techniques; Isoproterenol; Mice; Mice, Inbred Strains; Myocytes, Cardiac; Nifedipine; Tachycardia, Ventricular | 2004 |
The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature.
Topics: Acetylcholine; Animals; Anions; Antioxidants; Calcitonin Gene-Related Peptide; Coronary Vessels; Dose-Response Relationship, Drug; Guanylate Cyclase; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Nifedipine; Nitrites; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Peptide Fragments; Perfusion; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Vasodilation | 2007 |
Novel tissue engineered tubular heart tissue for in vitro pharmaceutical toxicity testing.
Topics: Animal Testing Alternatives; Animals; Apoptosis; Caspase 3; Collagen; Isoproterenol; Lidocaine; Microscopy, Confocal; Myocytes, Cardiac; Nifedipine; Rats; Tissue Engineering; Toxicity Tests; Xenobiotics | 2007 |
Ca2+/calmodulin kinase II increases ryanodine binding and Ca2+-induced sarcoplasmic reticulum Ca2+ release kinetics during beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Isoproterenol; Isoquinolines; Kinetics; Male; Nifedipine; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum; Sulfonamides | 2007 |
Tryptophan hydroxylase is modulated by L-type calcium channels in the rat pineal gland.
Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Arylalkylamine N-Acetyltransferase; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Chromatography, High Pressure Liquid; Cyclic CMP; Dose-Response Relationship, Drug; Electrochemistry; In Vitro Techniques; Isoproterenol; Melatonin; Nifedipine; Norepinephrine; Pineal Gland; Rats; Rats, Wistar; Serotonin; Tryptophan Hydroxylase | 2008 |
Conformational changes of a Ca2+-binding domain of the Na+/Ca2+ exchanger monitored by FRET in transgenic zebrafish heart.
Topics: Animals; Animals, Genetically Modified; Caffeine; Calcium Signaling; DNA, Antisense; Dogs; Embryo, Nonmammalian; Fluorescence Resonance Energy Transfer; Heart; Isoproterenol; Myocardial Contraction; Nifedipine; Ouabain; Peptide Fragments; Protein Conformation; Protein Structure, Tertiary; Sodium-Calcium Exchanger; Troponin T; Zebrafish; Zebrafish Proteins | 2008 |
Cyclic mechanical stress and trabecular meshwork cell contractility.
Topics: Actins; Amides; Blotting, Western; Cells, Cultured; Cytoskeleton; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Humans; Immunoblotting; Isoproterenol; L-Lactate Dehydrogenase; Microscopy, Fluorescence; Myosin Light Chains; Nifedipine; Phosphorylation; Pilocarpine; Pressure; Pyridines; rho-Associated Kinases; Stress, Mechanical; Trabecular Meshwork | 2009 |
Sinoatrial tissue of crucian carp heart has only negative contractile responses to autonomic agonists.
Topics: Acclimatization; Action Potentials; Animals; Calcium Channels; Calcium Channels, L-Type; Carbachol; Carps; Cholinergic Agonists; Cold Temperature; Enzyme Inhibitors; Heart Rate; Hot Temperature; Hypoxia; Isoproterenol; Myocardial Contraction; Nifedipine; Nitric Oxide Synthase; omega-N-Methylarginine; Parasympathetic Nervous System; Potassium Channels; Seasons; Sinoatrial Node; Species Specificity; Sympathetic Nervous System | 2010 |
Carbon dioxide enhances substance P-induced epithelium-dependent bronchial smooth muscle relaxation in Sprague-Dawley rats.
Topics: Animals; Bronchi; Calcium; Carbon Dioxide; Drug Synergism; Epithelium; Hydrogen-Ion Concentration; Hypercapnia; Hypocapnia; Isoproterenol; Male; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Nifedipine; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Substance P | 2011 |
Contractile properties of early human embryonic stem cell-derived cardiomyocytes: beta-adrenergic stimulation induces positive chronotropy and lusitropy but not inotropy.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Cell Survival; Cells, Cultured; Coculture Techniques; Depression, Chemical; Dose-Response Relationship, Drug; Embryonic Stem Cells; Heart Rate; Humans; Isoproterenol; Mice; Mice, 129 Strain; Myocardial Contraction; Myocytes, Cardiac; Nifedipine; Stimulation, Chemical; Ventricular Function | 2012 |
Cardiovascular effect of nifedipine in morphine dependent rats: hemodynamic, histopathological, and biochemical evidence.
Topics: Analgesics, Opioid; Animals; Blood Pressure; Calcium Channel Blockers; Dimethyl Sulfoxide; Heart Injuries; Heart Rate; Isoproterenol; Male; Morphine; Morphine Dependence; Nifedipine; Rats; Rats, Wistar; Troponin I | 2012 |
Protein kinase A regulation of T-type Ca2+ channels in rat cerebral arterial smooth muscle.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Carbazoles; Cations, Divalent; Cerebral Arteries; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelial Cells; Endothelium, Vascular; Female; Gene Expression Regulation; Isoproterenol; Nickel; Nifedipine; Patch-Clamp Techniques; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction | 2013 |
The effects of calcium channel blockade on proliferation and differentiation of cardiac progenitor cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cyclin B1; Embryo, Mammalian; Gene Expression Regulation, Developmental; Isoproterenol; MEF2 Transcription Factors; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Myocytes, Cardiac; Nifedipine; Stem Cells | 2014 |
Non-Invasive Acoustical sensing of Drug-Induced Effects on the Contractile Machinery of Human Cardiomyocyte Clusters.
Topics: Biosensing Techniques; Cell Line; Cytochalasin D; Humans; Isoproterenol; Myocytes, Cardiac; Nifedipine; Piperidines; Pyridines; Quartz Crystal Microbalance Techniques | 2015 |
β-Adrenoceptor activation enhances L-type calcium channel currents in anterior piriform cortex pyramidal cells of neonatal mice: implication for odor learning.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Electric Stimulation; Isoproterenol; Mice; Nifedipine; Odorants; Patch-Clamp Techniques; Piriform Cortex; Pyramidal Cells; Receptors, Adrenergic, beta | 2017 |
Exclusion of alternative exon 33 of Ca
Topics: Action Potentials; Alternative Splicing; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Colforsin; Electrophysiological Phenomena; Heart Failure; Isoproterenol; Long QT Syndrome; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Nifedipine; Rats; Sequence Deletion; Tachycardia; Ventricular Premature Complexes | 2017 |
Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acceleration; Gravity, Altered; Humans; Hypergravity; Induced Pluripotent Stem Cells; Isoproterenol; Myocytes, Cardiac; Nifedipine; Space Flight; Weightlessness | 2019 |
Development and evaluation of next-generation cardiotoxicity assay based on embryonic stem cell-derived cardiomyocytes.
Topics: Animals; Cardiotoxicity; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Doxorubicin; Embryonic Stem Cells; Humans; Induced Pluripotent Stem Cells; Isoproterenol; Male; Myocytes, Cardiac; Nifedipine; Rats; Rats, Sprague-Dawley | 2020 |