nifedipine has been researched along with indomethacin in 175 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (20.00) | 18.7374 |
| 1990's | 50 (28.57) | 18.2507 |
| 2000's | 36 (20.57) | 29.6817 |
| 2010's | 48 (27.43) | 24.3611 |
| 2020's | 6 (3.43) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Bhole, RP; Bhusari, KP; Chikhale, RV; Khedekar, PB | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Cogan, C; Frankish, NH; Jordan, M; McCabe, T; Passante, E; Sheridan, H; Walsh, JJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Sen, S; Sinha, N | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Beaumont, K; Di, L; Maurer, TS; Smith, DA | 1 |
| Bennis, K; Ducki, S; Lesage, F; Vivier, D | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Chang, G; Mathialagan, S; Ryu, S; Varma, MVS; Woody, N | 1 |
| Andersson, KE; Sjögren, C | 1 |
| Nowotny, P; Vierhapper, H; Wagner, OF; Waldhäusl, W | 1 |
| Hamilton, CA; Huang, YT; Reid, JL | 1 |
| Fogari, R; Malamani, GD; Salvetti, A; Tettamanti, F; Tinelli, C; Zoppi, A | 1 |
| Achmad, TH; Rao, GS | 1 |
| Koelbel, CB; Leduc, L; Mayer, EA; Snape, WJ; Vandeventer, G | 1 |
| Christ, GJ; Maayani, S; Melman, A; Valcic, M | 1 |
| Del Bianco, E; Geppetti, P; Maggi, CA; Patacchini, R; Santicioli, P; Tramontana, M | 1 |
| Schentke, KU; Zillmann, M | 1 |
| Baskin, DS; Bogue, L; Dudley, AW; Rothenberg, F; Simpson, RK | 1 |
| Quilley, J; Sarubbi, D | 1 |
| Nebel, U; Wermelskirchen, D; Wilffert, B; Wirth, A | 1 |
| Daly, RN; Duesler, JG; Hieble, JP | 1 |
| Allen, CN; Gray, TJ; Harpur, ES; Hirst, BH; Simmons, NL | 1 |
| Iravani, MM; Luheshi, GN; Zar, MA | 1 |
| MacLennan, SJ; McGrath, JC; Whittle, MJ | 1 |
| Cecconi, R; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P | 1 |
| Giuliani, S; Maggi, CA; Meli, A; Patacchini, R | 1 |
| Godfraind, T; Schoeffter, P | 1 |
| Gardner, RM; Stancel, GM | 1 |
| Beubler, E; Bukhave, K; Kollar, G; Rask-Madsen, J; Saria, A | 1 |
| Bertaccini, G; Coruzzi, G; Montanari, C; Poli, E | 1 |
| Braquet, P; Chabrier, PE; Lagente, V; Mencia-Huerta, JM | 1 |
| Collins-Williams, C | 1 |
| Dawson, AP; Hill, CE; Olson, MS; Pryor, JS | 1 |
| Herman, AG; Van Diest, MJ; Verbeuren, TJ | 1 |
| Davis, C; Kannan, L; Kannan, MS; Ladenius, AR; Sankaranarayanan, A | 1 |
| Murlas, CG; Thorpe, JE | 1 |
| Dieperink, H; Jørgensen, KA; Kemp, E; Leyssac, PP; Starklint, H | 1 |
| Conte, B; Giuliani, S; Maggi, CA; Manzini, S; Meli, A; Parlani, M | 1 |
| Anklesaria, P; Dalvi, SS; Kshirsagar, NA; Shah, SJ; Suraokar, S; Temulkar, P; Thatte, UM | 1 |
| Blaser, KU; Lämmle, B | 1 |
| Goto, M; Katayama, K; Shirota, H | 1 |
| Fujiwara, T; Itoh, T; Kuriyama, H | 1 |
| Agrawal, DK; McNeill, JH | 1 |
| Campese, V; Horton, R; McKay, M; Nadler, JL; Vrbanac, J | 1 |
| Magagna, A; Pedrinelli, R; Salvetti, A; Scapellato, L; Stornello, M | 1 |
| Knee, CD; Krell, RD; Kusner, EJ | 1 |
| Herreros, R; Huidobro-Toro, JP; Pinto-Corrado, A | 1 |
| Barrow, SE; Conway, EL; Murphy, MB; Orchard, MA | 1 |
| Aya, S; Kitamura, M; Ogawa, T; Sakuda, M; Yoneda, T | 1 |
| Bentwich, Z; Bibi, H; Eliraz, A; Fink, A; Tabachnik, E | 1 |
| Clark, JS; Jubb, SN; Maloney, PJ; Young, JM | 1 |
| Andersson, KE; Husted, S; Sjögren, C | 2 |
| Auclair, MC; Carli, A; Vernimmen, C | 1 |
| Burka, JF; Saad, MH | 1 |
| Halawa, B; Mazurek, W | 1 |
| Inoue, H; Koshihara, Y; Nagata, N | 1 |
| Mizusawa, H; Omote, M | 1 |
| Giachetti, A; Maggi, CA; Santicioli, P; Zagorodnyuk, V | 1 |
| Choudhury, Q; Croxtall, JD; Flower, RJ; Tokumoto, H | 1 |
| McCall, R; McGrath, JC; Nally, JE; Thomson, NC; Wakelam, MJ; Young, LC | 1 |
| el-Tahtawy, AA; Jackson, AJ; Ludden, TM | 1 |
| Church, DJ; Lang, U; Vallotton, MB; Van der Bent, V | 1 |
| Hatano, Y; Kakuyama, M; Mori, K; Nakamura, K; Nishiwada, M; Terasako, K; Toda, H | 1 |
| Divish, B; Langenstroer, P; Lepor, H; Opgenorth, T; Shapiro, E; Tang, R | 1 |
| Drapeau, G; Grose, JH; Levesque, L; Marceau, F; Rioux, F | 1 |
| Kanagy, NL; Webb, RC | 1 |
| Endo, C; Hoshi, K; Nakanishi, H; Okawa, T; Sato, A; Suzuki, H; Suzuki, Y | 1 |
| McGrath, JC; Smith, GC | 1 |
| Nelson, DJ; Shandy, T; Soliven, B; Takeda, M | 1 |
| Fozard, JR; Milavec-Krizman, M | 1 |
| Abram, TS; Cuthbert, NJ; Gardiner, PJ; Norman, P; Tudhope, SR | 1 |
| Conte, D; Fillo, S; Isidori, A; Nordio, M; Questino, P; Romanelli, F | 1 |
| Bridges, MT; Grover, TE; Introna, RP; Pruett, JK; Yodlowski, EH | 1 |
| Furukawa, T; Kushiku, K; Kuwahara, T; Tokunaga, R; Tsutsumi, S | 1 |
| Allegri, L; Borghetti, A; Buzio, C; Garini, G; Mazzi, A; Mutti, A; Savazzi, G | 1 |
| Akopov, SE | 1 |
| Kang, BS; Lee, EY; Lee, HY; Lee, YH | 1 |
| Imanaga, I; Inoue, M; Sakamoto, Y | 1 |
| Cheung, KK; Huang, Y | 1 |
| Costa, G; García-Pascual, A; Jimenez, E; Labadía, A; Triguero, D | 1 |
| Daniel, EE; Janssen, LJ; McGrogan, I; O'Byrne, PM; Wattie, J | 1 |
| Huang, KL; Lin, YC | 1 |
| Barna, TJ; Lamb, FS | 1 |
| Kokoska, ER; Miller, TA; Smith, GS | 1 |
| Connolly, C; Docherty, JR; McCormick, PA | 1 |
| Fonteles, MC; Júnior, EO; Martins, AM; Menezes, DB; Monteiro, HS | 1 |
| Hermann, M; Müller, GA; Ruschitzka, F; Schulz, E | 1 |
| Farfel, Z; Hourvitz, A; Mayan, H; Schiff, E | 1 |
| Kankaanranta, H; Li, L; Vaali, K; Vapaatalo, H | 1 |
| Bischoff, A; Michel, MC | 1 |
| Hannah, ME | 1 |
| Bates, JN; Hoque, A; Lewis, SJ; Travis, MD | 1 |
| Aragona, F; Malendowicz, LK; Nussdorfer, GG; Rebuffat, P; Tortorella, C | 1 |
| AL-Shabanah, O; EL-Kashef, H; Khattab, M | 1 |
| Kito, Y; Suzuki, H; Yoneda, S | 1 |
| Fu, C; Jiang, X; Zhao, L | 1 |
| Brewer, K; Gao, J; Harty, RF; Liang, K; Ren, J; Wang, Y | 1 |
| Araie, M; Fukaya, Y; Hosokawa, T; Ishii, K; Takayama, J; Tamaki, Y; Tomidokoro, A | 1 |
| Apperley, D; Forster, A; Hempenstall, J; Lancaster, R; Rades, T | 1 |
| Ambrosio, SR; da Costa, FB; de Oliveira, AM; Tirapelli, CR | 1 |
| Forster, A; Hempenstall, J; Rades, T | 1 |
| Araie, M; Takayama, J; Tamaki, Y; Tomidokoro, A | 1 |
| Apperley, DC; Forster, AH; Fournier, R; Harris, RK; Hodgkinson, P; Lancaster, RW; Rades, T | 1 |
| Berglund, M; Dalence-Guzmán, MF; Jönsson, P; Persson, CG; Skogvall, S; Sterner, O; Svensson, K | 1 |
| Ito, S; Ito, Y; Kondo, M; Kume, H; Naruse, K; Oguma, T; Shimokata, K; Suki, B | 1 |
| Bisits, A; Giles, W | 1 |
| Aalkjaer, C; Hughes, A; Matchkov, V; Nilsson, H; Rahman, A | 1 |
| Bhugra, C; Krill, SL; Pikal, MJ; Shmeis, R | 1 |
| Assreuy, AM; Criddle, DN; de Freitas Pires, A; Lima, RF; Soares, PM; Souza, EP | 1 |
| Baxter, J; Hayes, E; Moroz, L; Pizzi, L | 1 |
| Basak, F; Cehreli, SB; Cehreli, ZC; Guven, G; Kaya, E; Seyrek, M; Ulku, C; Vural, IM; Yildiz, O | 1 |
| Bagcivan, I; Durmus, N; Karadas, B; Kaya, T; Parlak, A; Toker, M; Topalkara, A | 1 |
| Sun, Y; Tao, J; Yu, L; Zhang, GG | 2 |
| Circosta, C; De Pasquale, R; Occhiuto, F; Palumbo, DR; Pino, A; Samperi, S; Sturlese, E | 1 |
| Miura, R; Nakao, Y; Naruhashi, K; Nishumura, A; Shibata, N | 1 |
| Camacho, A; Díaz, E; Díaz, F; Figueroa, L; Marvin, R | 1 |
| Betancourt, A; Bytautiene, E; Chiossi, G; Costantine, MM; Hankins, GD; Longo, M; Saade, GR | 1 |
| Derbent, A; Gümüş, II; Simavli, S; Tatli, MM; Turhan, NO | 1 |
| Cehreli, ZC; Guven, G; Seyrek, M; Vural, IM; Yildiz, O | 1 |
| Bahasadri, S; Kashanian, M; Zolali, B | 1 |
| Cedillo, FD; Cervera, EG; Cordoba, J; Quijano, K; Ramos, ML; Valverde, LF | 1 |
| Baykal, C; Kaya, S; Takal, MK; Yakupoğlu, U | 1 |
| Balducci, J; Baumbach, J; Coonrod, DV; Garfield, RE; Shi, L; Shi, SQ | 1 |
| Abramovici, A; Cantu, J; Jenkins, SM | 1 |
| Cui, X; Ding, DZ; Hong, L; Jin, SJ; Li, HY; Liu, LP; Yu, L | 1 |
| Briery, CM; Keiser, SD; Klauser, CK; Kosek, MA; Martin, RW; Morrison, JC | 1 |
| Ayon, RJ; Davis, AJ; Duan, DD; Forrest, AS; Freitas, N; Greenwood, IA; Huebner, ML; Joyce, J; Joyce, TC; Leblanc, N; Singer, CA; Valencik, ML; Wiwchar, M; Ye, L | 1 |
| De Lisle, RC | 1 |
| Mimura, H; Nasu, M; Nemoto, T; Sako, K | 1 |
| Fujii, M; Kanada, K; Koizumi, N; Shibata, Y; Suzuki, A; Watanabe, Y; Yamada, M | 1 |
| Briery, CM; Klauser, CK; Langston, L; Magann, EF; Martin, RW; Morrison, JC | 1 |
| Auteri, M; Mastropaolo, M; Mulè, F; Serio, R; Zizzo, MG | 1 |
| de Villiers, MM; Derdour, L; Huang, J; Hussain, MA; Qian, F; Yu, L; Zhang, SW | 1 |
| Saraf, MN; Shirole, NL; Shirole, RL | 1 |
| Briery, CM; Chauhan, SP; Klauser, CK; Magann, EF; Martin, RW; Morrison, JC; Tucker, AR | 1 |
| Bu, Y; Chinannai, KS; Choi, HY; Ham, I; Kim, B; Kim, H; Lee, K | 1 |
| Cool, DR; Grunwald, WC; Haidar, ZA; Mckenna, DS; Sammohi, S; Sibai, BM; Sonek, JD | 1 |
| Ebrahimi, A; Langrish, T; Saffari, M | 1 |
| Butler, T; Hua, S; Ilicic, M; Paul, JW; Robertson, S; Smith, R; Tolosa, JM | 1 |
| Desai, P; Gage, JA; Godin, B; Leonard, F; Liao, A; Longo, M; Mani, A; Refuerzo, JS; Souza, GR; Tseng, H | 1 |
| Gui, Y; Teerakapibal, R; Yu, L | 1 |
| Govindaswami, B; Jegatheesan, P; Narasimhan, SR; Nudelman, M | 1 |
| Ben Osman, Y; Liavitskaya, T; Vyazovkin, S | 1 |
| Javanmanesh, F; Kashanian, M; Sheikhansari, N; Shirvani, S | 1 |
| Kadota, K; Tanida, S; Tozuka, Y; Uchiyama, H; Yoshida, M; Yoshimoto, A | 1 |
| Emeruwa, UN; Krenitsky, NM; Sheen, JJ | 1 |
| Abdelrahiem, SK; Adam, I; Elfaki, T; Elhassan, EM; Ibrahim, MH | 1 |
| Pei, S; Xiong, Z; Zhu, Z | 1 |
| Hossain, MR; Paul, JW; Smith, R; Tolosa, JM; Young, RC | 1 |
7 review(s) available for nifedipine and indomethacin
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship | 2016 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Preterm labour. The present and future of tocolysis.
Topics: Adrenergic beta-Agonists; Female; Humans; Indomethacin; Magnesium Sulfate; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolytic Agents; Treatment Failure; Vasotocin | 2007 |
Tocolytic therapy for acute preterm labor.
Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Magnesium Compounds; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy, High-Risk; Tocolysis; Tocolytic Agents; United States | 2012 |
Prevention of Prematurity: Advances and Opportunities.
Topics: Anti-Infective Agents; Aspirin; Cerclage, Cervical; Cesarean Section; Female; Humans; Indomethacin; Labor, Induced; Magnesium Sulfate; Nifedipine; Pharmacogenetics; Platelet Aggregation Inhibitors; Preconception Care; Pregnancy; Premature Birth; Progesterone; Progestins; Reproductive Techniques, Assisted; Smoking Cessation; Tocolytic Agents | 2018 |
Advances in Management for Preterm Fetuses at Risk of Delivery.
Topics: Anti-Bacterial Agents; Anticonvulsants; Betamethasone; Dexamethasone; Female; Fetal Membranes, Premature Rupture; Fetal Organ Maturity; Fetal Viability; Glucocorticoids; Humans; Indomethacin; Magnesium Sulfate; Neonatal Sepsis; Neuroprotective Agents; Nifedipine; Pregnancy; Premature Birth; Streptococcal Infections; Streptococcus agalactiae; Tocolysis; Tocolytic Agents | 2020 |
Four kinds of tocolytic therapy for preterm delivery: Systematic review and network meta-analysis.
Topics: Female; Humans; Indomethacin; Infant; Infant, Newborn; Network Meta-Analysis; Nifedipine; Obstetric Labor, Premature; Pregnancy; Premature Birth; Tocolysis; Tocolytic Agents | 2022 |
10 trial(s) available for nifedipine and indomethacin
| Article | Year |
|---|---|
Effect of endothelin-1 in man: pretreatment with nifedipine, with indomethacin and with cyclosporine A.
Topics: Adult; Blood Pressure; Calcium Channels; Cyclosporine; Drug Interactions; Endothelins; Humans; Indomethacin; Infusions, Intravenous; Male; Nifedipine; Potassium | 1992 |
Effects of nifedipine and indomethacin on cough induced by angiotensin-converting enzyme inhibitors: a double-blind, randomized, cross-over study.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cough; Double-Blind Method; Female; Heart Rate; Humans; Indomethacin; Male; Middle Aged; Nifedipine; Prostaglandins | 1992 |
The effects of nifedipine on platelet aggregation and plasma 6-keto-PGF1 alpha, and its interaction with indomethacin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Female; Humans; Hypertension; Indomethacin; Male; Middle Aged; Nifedipine; Platelet Aggregation; Random Allocation; Rats | 1985 |
Comparison of single and multiple dose pharmacokinetics using clinical bioequivalence data and Monte Carlo simulations.
Topics: Adolescent; Adult; Cross-Over Studies; Erythromycin; Humans; Indomethacin; Male; Middle Aged; Monte Carlo Method; Nifedipine; Procainamide; Quinidine; Therapeutic Equivalency | 1994 |
Comparison of the efficacy and adverse effects of nifedipine and indomethacin for the treatment of preterm labor.
Topics: Adult; Drug Administration Schedule; Female; Humans; Indomethacin; Nifedipine; Obstetric Labor, Premature; Pregnancy; Premature Birth; Tocolytic Agents; Treatment Outcome | 2011 |
Effect of antenatal tocolysis on neonatal outcomes.
Topics: Female; Gestational Age; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Magnesium Sulfate; Morbidity; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Tocolysis; Tocolytic Agents | 2012 |
A comparison of three tocolytics for preterm labor: a randomized clinical trial.
Topics: Adolescent; Adult; Drug Administration Routes; Female; Gestational Age; Humans; Indomethacin; Magnesium Sulfate; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolysis; Tocolytic Agents; Treatment Outcome; Young Adult | 2014 |
Tocolysis in women with advanced preterm labor: a secondary analysis of a randomized clinical trial.
Topics: Administration, Intravenous; Administration, Oral; Administration, Rectal; Adolescent; Adult; Female; Humans; Indomethacin; Infant, Newborn; Labor Stage, First; Magnesium Sulfate; Nifedipine; Obstetric Labor, Premature; Pregnancy; Suppositories; Tocolysis; Tocolytic Agents; Young Adult | 2016 |
A comparative study on the efficacy of nifedipine and indomethacin for prevention of preterm birth as monotherapy and combination therapy: a randomized clinical trial.
Topics: Female; Humans; Indomethacin; Infant; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Pregnancy; Premature Birth; Tocolytic Agents | 2020 |
The effectiveness of nifedipine/indomethacin combination therapy and nifedipine monotherapy for postponing preterm birth (25-34 weeks of gestation) in Sudanese women: a randomized clinical trial study protocol.
Topics: Adolescent; Adult; Combined Modality Therapy; Female; Gestational Age; Humans; Indomethacin; Infant, Newborn; Labor Stage, First; Nifedipine; Pregnancy; Premature Birth; Randomized Controlled Trials as Topic; Sudan; Tocolysis; Tocolytic Agents; Young Adult | 2021 |
158 other study(ies) available for nifedipine and indomethacin
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Synthesis and pharmacological investigation of 3-(substituted 1-phenylethanone)-4-(substituted phenyl)-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Edema; Hypertension; Inflammation; Male; Mice; Pain Measurement; Pyrimidines; Rats; Stomach; Ulcer | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Diastereoisomers of 2-benzyl-2, 3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol: potential anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; beta-N-Acetylhexosaminidases; Cell Line; Crystallography, X-Ray; Guinea Pigs; Histamine; Indenes; Mice; Molecular Conformation; Rats; Stereoisomerism | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Volume of Distribution in Drug Design.
Topics: Drug Design; Half-Life; Pharmacokinetics | 2015 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Identification of Organic Anion Transporter 2 Inhibitors: Screening, Structure-Based Analysis, and Clinical Drug Interaction Risk Assessment.
Topics: Drug Interactions; HEK293 Cells; Humans; Liver; Organic Anion Transporters, Sodium-Independent; Risk Assessment | 2022 |
Inhibition of ATP-induced contraction in the guinea-pig urinary bladder in vitro and in vivo.
Topics: Adenosine; Adenosine Triphosphate; Amines; Animals; Female; Guinea Pigs; Indomethacin; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Parasympatholytics; Propranolol; Tetrodotoxin; Theophylline; Urinary Bladder | 1979 |
Effects of endothelin upon blood pressure in normotensive rabbits and in perinephritis hypertension.
Topics: Animals; Arginine; Blood Pressure; Calcium; Calcium Channel Blockers; Endothelins; Hypertension; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Perinephritis; Prostaglandins; Rabbits; Time Factors | 1992 |
Chemotaxis of human blood monocytes toward endothelin-1 and the influence of calcium channel blockers.
Topics: Aspirin; Calcium Channel Blockers; Chemotaxis, Leukocyte; Diltiazem; Dose-Response Relationship, Drug; Endothelins; Humans; In Vitro Techniques; Indomethacin; Kinetics; Monocytes; Neomycin; Nifedipine; Probucol; Thioctic Acid; Verapamil | 1992 |
Neurokinin inhibition of cholinergic myenteric neurons in canine antrum.
Topics: Acetylcholine; Animals; Atropine; Dinoprostone; Dogs; Electric Stimulation; Enkephalin, Methionine; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth; Myenteric Plexus; Naloxone; Neurokinin A; Neurons; Nifedipine; Phentolamine; Propranolol; Pyloric Antrum; Substance P; Tetrodotoxin; Vasoactive Intestinal Peptide | 1990 |
Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in alpha-adrenoceptor responsiveness with age and disease in isolated tissues.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Aged; Aged, 80 and over; Aging; Diabetes Complications; Erectile Dysfunction; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Penile Erection; Penis; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha | 1990 |
Low pH-induced release of calcitonin gene-related peptide from capsaicin-sensitive sensory nerves: mechanism of action and biological response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acids; Animals; Calcitonin Gene-Related Peptide; Calcium Channels; Capsaicin; Guinea Pigs; Hydrogen-Ion Concentration; Indomethacin; Isoquinolines; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Neurosecretion; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Piperazines; Potassium; Ruthenium Red; Tetrodotoxin; Urinary Bladder | 1991 |
[Ultrasonography studies on spontaneous and pharmacologically modified gallbladder motility].
Topics: Adult; Butylscopolammonium Bromide; Cholagogues and Choleretics; Circadian Rhythm; Female; Gallbladder; Gallbladder Emptying; Gastrointestinal Motility; Humans; Indomethacin; Male; Middle Aged; Nifedipine; Sorbitol | 1991 |
The influence of long-term nifedipine or indomethacin therapy on neurologic recovery from experimental spinal cord injury.
Topics: Animals; Evoked Potentials; Evoked Potentials, Somatosensory; Indomethacin; Nifedipine; Prostaglandins; Rats; Rats, Inbred Strains; Spinal Cord; Spinal Cord Injuries | 1991 |
Evidence against a role of arachidonic acid metabolites in autoregulatory responses of the isolated perfused kidney of the rat.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cytochrome P-450 Enzyme Inhibitors; Diabetes Mellitus, Experimental; Dinoprostone; In Vitro Techniques; Indomethacin; Kidney; Male; Nifedipine; Perfusion; Rats; Rats, Inbred Strains; Renal Circulation; Vascular Resistance | 1991 |
45Ca2+ movements induced by Ca2+ chloride in isolated rat aorta under K(+)-free conditions.
Topics: Amiloride; Animals; Aorta, Thoracic; Benzothiazoles; Calcium; Calcium Chloride; Calcium Radioisotopes; Flunarizine; In Vitro Techniques; Indomethacin; Lanthanum; Lidocaine; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Piperidines; Potassium; Rats; Thiazoles; Vasoconstriction | 1991 |
Studies on the mechanism of neuropeptide Y induced potentiation of neurogenic vasoconstriction in the isolated rabbit ear artery.
Topics: Animals; Arteries; Calcium; Cyclooxygenase Inhibitors; Ear; Electric Stimulation; Indomethacin; Infusions, Intra-Arterial; Neuropeptide Y; Nifedipine; Rabbits; Sympathetic Nervous System; Vasoconstriction | 1990 |
Efflux of bis-carboxyethyl-carboxyfluorescein (BCECF) by a novel ATP-dependent transport mechanism in epithelial cells.
Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Cell Line; Epithelium; Fluoresceins; Fluorescent Dyes; Humans; Indomethacin; Kinetics; Nifedipine; Reserpine; Verapamil; Vinblastine | 1990 |
Effect of nifedipine on the contractile responses of the isolated rat bladder.
Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Neural Conduction; Nifedipine; Physostigmine; Rats; Tetrodotoxin; Urinary Bladder | 1990 |
Inhibition of the oxygen-induced contraction of the isolated human umbilical artery by indomethacin, flurbiprofen, aspirin and drugs modifying Ca2+ disposition.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aspirin; Calcium; Female; Flurbiprofen; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Oxygen; Partial Pressure; Pregnancy; Propionates; Reference Values; Umbilical Arteries | 1988 |
Multiple mechanisms in the motor responses of the guinea-pig isolated urinary bladder to bradykinin.
Topics: Animals; Apamin; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; Indomethacin; Kallidin; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Substance P; Tetrodotoxin; Thiorphan; Urinary Bladder | 1989 |
Potent contractile effect of endothelin in isolated guinea-pig airways.
Topics: Animals; Bronchi; Edetic Acid; Endothelins; Guinea Pigs; In Vitro Techniques; Indomethacin; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nifedipine; Peptides; Tetrodotoxin; Trachea | 1989 |
Spontaneous rhythmic contractions of human saphenous veins isolated from old subjects are sensitive to cyclooxygenase inhibitors.
Topics: Adult; Aged; Aging; Aspirin; Coronary Artery Bypass; Cyclooxygenase Inhibitors; Female; Histamine; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle Development; Muscle, Smooth; Nifedipine; Norepinephrine; Phentolamine; Prazosin; Pyrilamine; Saphenous Vein | 1989 |
Blockade of epidermal growth factor-induced uterine contractions by indomethacin or nordihydroguaritic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Catechols; Chlorpromazine; Epidermal Growth Factor; Female; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Nifedipine; Rats; Uterine Contraction | 1989 |
Involvement of 5-hydroxytryptamine, prostaglandin E2, and cyclic adenosine monophosphate in cholera toxin-induced fluid secretion in the small intestine of the rat in vivo.
Topics: Animals; Body Fluids; Cholera Toxin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Female; Indomethacin; Intestine, Small; Ketanserin; Nifedipine; Rats; Rats, Inbred Strains; Serotonin; Time Factors; Verapamil | 1989 |
Pharmacological characterization of mare uterus motility with special reference to calcium antagonists and beta-2-adrenergic stimulants.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Calcium Channel Blockers; Culture Media; Cyclic AMP; Diltiazem; Female; Hexoprenaline; Horses; In Vitro Techniques; Indomethacin; Myometrium; Nifedipine; Tetrodotoxin; Uterine Contraction; Verapamil | 1989 |
Pharmacological modulation of the bronchopulmonary action of the vasoactive peptide, endothelin, administered by aerosol in the guinea-pig.
Topics: Aerosols; Animals; Blood Pressure; Bronchi; Diterpenes; Endothelins; Endothelium, Vascular; Ginkgolides; Guinea Pigs; Indomethacin; Lactones; Male; Nifedipine; Peptides; Plant Extracts; Platelet Activating Factor; Propranolol; Pyrilamine; Verapamil | 1989 |
The role of pharmacologic agents in the prevention or treatment of allergic food disorders.
Topics: Administration, Oral; Adult; Aspirin; Beclomethasone; Child; Cromolyn Sodium; Dermatitis, Atopic; Food Hypersensitivity; Histamine H1 Antagonists; Humans; Ibuprofen; Indomethacin; Infant; Ketotifen; Nifedipine | 1986 |
Potassium-mediated stimulation of hepatic glycogenolysis.
Topics: Animals; Atrial Natriuretic Factor; Atropine; Egtazic Acid; In Vitro Techniques; Indomethacin; Kinetics; Liver; Liver Glycogen; Masoprocol; Nifedipine; Nitroprusside; Perfusion; Phentolamine; Potassium; Propranolol; Rats; Verapamil | 1987 |
Cyclo-oxygenase blockers influence the effects of 15-lipoxygenase metabolites of arachidonic acid in isolated canine blood vessels.
Topics: Animals; Arachidonate 15-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Dogs; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukotrienes; Lipid Peroxides; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine | 1986 |
Pharmacological characterization of airway smooth muscle responses to antigen in ascaris-sensitive dogs.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Airway Resistance; Animals; Antigens, Helminth; Arachidonic Acid; Arachidonic Acids; Ascaris; Asthma; Dogs; Dose-Response Relationship, Drug; Hypersensitivity; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Nifedipine; p-Methoxy-N-methylphenethylamine; Serotonin; Trachea | 1986 |
Effects of leukotriene D4 and antagonists of arachidonic acid metabolism and calcium entry on guinea pig tracheal muscle responsiveness.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Calcium Channel Blockers; Guinea Pigs; In Vitro Techniques; Indomethacin; Muscle Contraction; Nifedipine; Potassium Chloride; Pyrazoles; SRS-A; Trachea | 1986 |
Antagonist capacities of nifedipine, captopril, phenoxybenzamine, prostacyclin and indomethacin on cyclosporin A induced impairment of rat renal function.
Topics: Animals; Captopril; Cyclosporins; Epoprostenol; Indomethacin; Kidney; Male; Nifedipine; Phenoxybenzamine; Rats; Rats, Inbred Strains; Renal Circulation; Vasoconstriction; Vasodilator Agents | 1986 |
The effect of nifedipine on spontaneous, drug-induced and reflexly-activated contractions of the rat urinary bladder: evidence for the participation of an intracellular calcium store to micturition contraction.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carbachol; Edetic Acid; Hemodynamics; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Rats; Rats, Inbred Strains; Reflex; Urinary Bladder; Urination | 1988 |
Acute drug interaction between indomethacin and nifedipine in hypertensive patients.
Topics: Drug Interactions; Female; Humans; Hypertension; Indomethacin; Male; Middle Aged; Nifedipine | 1988 |
[Acute hyperkalemia and non-oliguric kidney failure during treatment with indomethacin, allopurinol, nifedipine, hydrochlorothiazide/amiloride, trimethoprim/sulfamethoxazole and acetylsalicylic acid].
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Allopurinol; Amiloride; Aspirin; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperkalemia; Indomethacin; Male; Nifedipine; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
Application of adjuvant-induced local hyperthermia for evaluation of anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Dinoprostone; Indomethacin; Male; Nifedipine; Rats; Rats, Inbred F344; Rats, Inbred Lew; Skin Temperature; Steroids; Vasoconstrictor Agents | 1988 |
Regional differences in the mechanical properties of rabbit airway smooth muscle.
Topics: Acetylcholine; Animals; Asthma; Bronchi; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium; Prostaglandins F; Rabbits; Thromboxane A2; Trachea | 1988 |
Effect of diabetes on vascular smooth muscle function in normotensive and spontaneously hypertensive rat mesenteric artery.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1987 |
Evidence that prostacyclin modulates the vascular actions of calcium in man.
Topics: 6-Ketoprostaglandin F1 alpha; Blood Pressure; Calcium; Creatinine; Dinoprostone; Drug Interactions; Epoprostenol; Hemodynamics; Humans; Ibuprofen; Indomethacin; Kidney; Natriuresis; Nifedipine; Potassium; Prazosin; Prostaglandins E; Regional Blood Flow; Sulindac; Vascular Resistance; Vasodilation | 1986 |
Calcium antagonists: interactions in hypertension.
Topics: Adult; Blood Pressure; Clonidine; Drug Interactions; Female; Humans; Hypertension; Indomethacin; Male; Middle Aged; Nifedipine; Renin | 1986 |
Pharmacologic analysis of 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine-induced increases in cutaneous vascular permeability in the rat.
Topics: Animals; Capillary Permeability; Chromones; Dose-Response Relationship, Drug; Indomethacin; Masoprocol; Methysergide; Nifedipine; Phenoxybenzamine; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Rats; Theophylline; Thiazoles | 1987 |
Pre- and postsynaptic bradykinin responses in the rat vas deferens: asymmetric distribution of the postsynaptic effect.
Topics: Animals; Bradykinin; Drug Interactions; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neurons; Nifedipine; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin; Vas Deferens; Verapamil | 1986 |
Control of VX2 carcinoma cell growth in culture by calcium, calmodulin, and prostaglandins.
Topics: Animals; Bone Resorption; Calcimycin; Calcium; Calmodulin; Carcinoma; Cell Division; Cell Line; DNA Replication; Fibroblasts; Indomethacin; Kinetics; Nifedipine; Prostaglandins; Rabbits; Skin; Sulfonamides | 1985 |
Leukotrienes (LTC4, LTD4) confer glass non-adherence on leukocytes of asthmatic individuals. Dependency on cyclooxygenase products and calcium ion.
Topics: Asthma; Calcium; Cell Adhesion; Child; Cyclooxygenase Inhibitors; Dinoprostone; Glass; Humans; Indomethacin; Lanthanum; Leukocyte Adherence Inhibition Test; Leukocytes; Lidocaine; Nifedipine; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; SRS-A; Trifluoperazine | 1985 |
Pharmacological investigation of the mechanisms of platelet-activating factor induced mortality in the mouse.
Topics: Anaphylaxis; Animals; Chloroquine; Chlortetracycline; Dexamethasone; Dose-Response Relationship, Drug; Female; Indomethacin; Injections, Intravenous; Male; Mice; Mice, Inbred DBA; Naproxen; Nicardipine; Nifedipine; Platelet Activating Factor; Pyrazoles; Quinacrine; Tetracycline; Verapamil | 1985 |
Direct effects of adenosine and adenine nucleotides on isolated human urinary bladder and their influence on electrically induced contractions.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adult; Aged; Atropine; Dipyridamole; Electric Stimulation; Female; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Prostaglandins; Purines; Synaptic Transmission; Theophylline; Urinary Bladder | 1983 |
Indomethacin suppresses the early cardiodepressant factor released by endotoxin in the rat: possible involvement of a prostacyclin-related material.
Topics: Animals; Caffeine; Cells, Cultured; Depression, Chemical; Epoprostenol; Imidazoles; Indomethacin; Male; Myocardial Contraction; Myocardial Depressant Factor; Nifedipine; Peptide Biosynthesis; Rats; Shock, Septic | 1983 |
Role of calcium in arachidonic acid-induced contractions of guinea pig airways.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Channel Blockers; Edetic Acid; Gallic Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Lanthanum; Lung; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; SRS-A; Trachea; Verapamil | 1984 |
[Interactions of digoxin and the nonsteroidal anti-inflammatory drugs, acetylsalicylic acid and nifedipine].
Topics: Adult; Arthritis; Aspirin; Coronary Disease; Digoxin; Drug Interactions; Humans; Indomethacin; Male; Middle Aged; Neuritis; Nifedipine; Phenylbutazone; Pyridines | 1982 |
Mechanisms of the responses to non-cholinergic, non-adrenergic nerve stimulation and to ATP in isolated rabbit urinary bladder: evidence for ADP evoked prostaglandin release.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Carbachol; Electric Stimulation; In Vitro Techniques; Indomethacin; Muscle Contraction; Nifedipine; Potassium; Prostaglandins; Rabbits; Urinary Bladder | 1980 |
Profile of capsaicin-induced mouse ear oedema as neurogenic inflammatory model: comparison with arachidonic acid-induced ear oedema.
Topics: Administration, Cutaneous; Animals; Arachidonic Acid; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cyproheptadine; Edema; Indomethacin; Male; Mice; Neuropeptides; Nifedipine; Substance P | 1993 |
Phenylephrine-induced rhythmic activity in the rabbit ear artery.
Topics: Animals; Arginine; Arteries; Charybdotoxin; Ear, External; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Male; Nifedipine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Periodicity; Phenylephrine; Potassium Channel Blockers; Prostaglandin Antagonists; Rabbits; Scorpion Venoms; Vasoconstriction | 1993 |
Evidence that tachykinin NK1 and NK2 receptors mediate non-adrenergic non-cholinergic excitation and contraction in the circular muscle of guinea-pig duodenum.
Topics: Action Potentials; Adenosine Diphosphate; Animals; Apamin; Arginine; Atropine; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Guanethidine; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; Nifedipine; Nitroarginine; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Suramin; Thionucleotides | 1995 |
Phospholipase A2-induced stimulation of A549 lung adenocarcinoma cell line proliferation.
Topics: Acetophenones; Calcium; Cell Division; Chromatography, Gel; Cytosol; Dexamethasone; Dinoprostone; Enzyme Activation; Humans; Indomethacin; Nifedipine; Phospholipases A; Phospholipases A2; Tumor Cells, Cultured | 1993 |
Mechanical and biochemical responses to endothelin-1 and endothelin-3 in human bronchi.
Topics: Atropine; Bronchi; Calcium; Dose-Response Relationship, Drug; Endothelins; Glycopeptides; Humans; In Vitro Techniques; Indoles; Indomethacin; Inositol 1,4,5-Trisphosphate; Muscle Contraction; Muscle, Smooth; Nifedipine; Phorbol 12,13-Dibutyrate; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protease Inhibitors; Protein Kinase C | 1994 |
Role of prostaglandin-mediated cyclic AMP formation in protein kinase C-dependent secretion of atrial natriuretic peptide in rat cardiomyocytes.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Atrial Natriuretic Factor; Bucladesine; Cells, Cultured; Cyclic AMP; Diclofenac; Dinoprost; Dinoprostone; Epoprostenol; Heart; Heart Ventricles; Indomethacin; Kinetics; Myocardial Contraction; Myocardium; Nifedipine; Prostaglandins; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thionucleotides | 1994 |
Halothane and enflurane constrict canine mesenteric arteries by releasing Ca2+ from intracellular Ca2+ stores.
Topics: Animals; Arginine; Caffeine; Calcium; Dogs; Enflurane; Fluorescent Dyes; Fura-2; Halothane; In Vitro Techniques; Indomethacin; Isometric Contraction; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitroarginine; Ryanodine; Spectrometry, Fluorescence; Vasoconstriction | 1994 |
Endothelin-1 in the human prostate: tissue levels, source of production and isometric tension studies.
Topics: Adrenergic alpha-Antagonists; Calcium; Dose-Response Relationship, Drug; Endothelins; Epithelium; Humans; Immunohistochemistry; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Muscle, Smooth; Nifedipine; Prazosin; Prostate | 1993 |
Vascular mode of action of kinin B1 receptors and development of a cellular model for the investigation of these receptors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Thoracic; Bradykinin; Bradykinin Receptor Antagonists; Calcium; Cells, Cultured; Female; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Inositol Phosphates; Lipoxygenase Inhibitors; Male; Models, Biological; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Protein Kinase Inhibitors; Rabbits; Receptors, Bradykinin; Signal Transduction | 1993 |
Enhanced vascular reactivity to mastoparan, a G protein activator, in genetically hypertensive rats.
Topics: Animals; Blood Vessels; Ethylmaleimide; GTP-Binding Proteins; Hypertension; In Vitro Techniques; Indomethacin; Intercellular Signaling Peptides and Proteins; Nifedipine; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Type C Phospholipases; Wasp Venoms | 1994 |
[Endothelin-1-induced contraction of pregnant rat myometrium: role of platelet-activating factor].
Topics: Animals; Dose-Response Relationship, Drug; Endothelins; Female; In Vitro Techniques; Indomethacin; Isoquinolines; Nifedipine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pregnancy; Pyridinium Compounds; Rats; Tetrahydroisoquinolines; Uterine Contraction | 1994 |
Characterisation of the effect of oxygen tension on response of fetal rabbit ductus arteriosus to vasodilators.
Topics: Adenosine; Animals; Atrial Natriuretic Factor; Benzopyrans; Colforsin; Cromakalim; Culture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Ductus Arteriosus; Epoprostenol; Flurbiprofen; Indomethacin; Nifedipine; Nitroprusside; Norepinephrine; Oxygen; Pyrroles; Rabbits; Vasodilator Agents | 1993 |
Arachidonic acid and its metabolites increase Cai in cultured rat oligodendrocytes.
Topics: Animals; Arachidonic Acids; Calcium; Calcium Channels; Cell Membrane; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Cobalt; Dose-Response Relationship, Drug; Fluorescence; Fura-2; Indomethacin; Linoleic Acid; Linoleic Acids; Manganese; Nifedipine; Oligodendroglia; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats | 1993 |
Contraction of the rat isolated spleen mediated by adenosine A1 receptor activation.
Topics: Adenosine; Animals; Biotransformation; Corpus Striatum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylisopropyladenosine; Prazosin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spleen; Swine | 1993 |
Characterisation of the peptido-leukotriene receptor PL2 on the ferret spleen strip.
Topics: Animals; Dose-Response Relationship, Drug; Ferrets; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotriene E4; Leukotrienes; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Receptors, Leukotriene; Spleen; SRS-A | 1993 |
Endothelin stimulates testosterone secretion by rat Leydig cells.
Topics: Animals; Cells, Cultured; Chorionic Gonadotropin; Dinoprostone; Dose-Response Relationship, Drug; Endothelins; Indomethacin; Leydig Cells; Male; Nifedipine; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Testosterone | 1993 |
Direct effects of fentanyl on canine coronary artery rings.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Intravenous; Animals; Arteries; Calcium Channel Blockers; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Fentanyl; In Vitro Techniques; Indomethacin; Male; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nifedipine; Prazosin; Propranolol; Vasoconstriction | 1995 |
Ionotropic mechanisms involved in postsynaptic inhibition by the endothelins of ganglionic transmission in dog cardiac sympathetic ganglia.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Calcium; Dimethylphenylpiperazinium Iodide; Dogs; Endothelins; Female; Ganglia, Sympathetic; Heart Rate; Indomethacin; Male; Nifedipine; Peptides, Cyclic; Potassium Channels; Synaptic Transmission | 1995 |
Renal effects of captopril, indomethacin and nifedipine in nephrotic patients after an oral protein load.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Calcium Channel Blockers; Captopril; Dietary Proteins; Female; Glomerular Filtration Rate; Humans; Indomethacin; Kidney; Male; Middle Aged; Nephrotic Syndrome; Nifedipine; Proteinuria; Sodium | 1996 |
Nitric oxide (EDRF) enhances the vasorelaxing effect of dihydropyridine calcium antagonists in isolated human middle cerebral arteries.
Topics: Adult; Arginine; Calcium Channel Blockers; Cerebral Arteries; Cyclooxygenase Inhibitors; Dihydropyridines; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Humans; In Vitro Techniques; Indomethacin; Isradipine; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Vasodilator Agents | 1996 |
Hypoxic contraction of isolated rat pulmonary artery.
Topics: Animals; Caffeine; Cell Hypoxia; Cyclooxygenase Inhibitors; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Nifedipine; Nitric Oxide; Oxygen; Pulmonary Artery; Rats; Vasoconstriction; Vasodilator Agents | 1995 |
Mn(2+)-induced transient contraction of the longitudinal muscle of guinea-pig stomach through prostaglandin synthesis.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Electric Stimulation; Enzyme Inhibitors; Female; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Manganese; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Phospholipases A; Phospholipases A2; Prostaglandins; Quinacrine; Stomach; Tetrodotoxin | 1996 |
Endothelium-dependent rhythmic contractions induced by cyclopiazonic acid in rat mesenteric artery.
Topics: Animals; Calcium Channel Blockers; Endothelium, Vascular; Enzyme Inhibitors; Indoles; Indomethacin; Mesenteric Arteries; Muscle Contraction; Nifedipine; Nitroarginine; Phenylephrine; Potassium Channels; Rats; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
Endothelin receptor-mediated Ca2+ mobilization and contraction in bovine oviductal arteries: comparison with noradrenaline and potassium.
Topics: Animals; Cadmium; Caffeine; Calcium; Calcium Channel Agonists; Cattle; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-2; Endothelin-3; Endothelium, Vascular; Fallopian Tubes; Female; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Nickel; Nifedipine; Nitroarginine; Norepinephrine; Peptides, Cyclic; Potassium; Receptors, Endothelin; Ryanodine; Viper Venoms | 1997 |
Myogenic and neurogenic mechanisms and arachidonate metabolites in bronchial muscle response to allergen.
Topics: Allergens; Animals; Arachidonic Acids; Ascaris suum; Bronchi; Bronchial Hyperreactivity; Carbachol; Dinoprostone; Dogs; Electric Stimulation; Female; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Chloride | 1997 |
Pharmacologic modulation of pulmonary vascular permeability during air embolism.
Topics: Animals; Capillary Permeability; Cyclooxygenase Inhibitors; Hypertension, Pulmonary; Indomethacin; Isoproterenol; Lung; Male; Nifedipine; Pulmonary Artery; Pulmonary Embolism; Rats; Rats, Wistar; Vascular Resistance | 1997 |
The endothelium modulates the contribution of chloride currents to norepinephrine-induced vascular contraction.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anthracenes; Aorta, Thoracic; Chloride Channels; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Models, Cardiovascular; Muscle, Smooth, Vascular; Nifedipine; Niflumic Acid; Nitric Oxide; Nitroarginine; Norepinephrine; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1998 |
Store-operated calcium influx in human gastric cells: role of endogenous prostaglandins.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Transport; Calcium; Calcium Channel Blockers; Cell Communication; Cell Line; Dinoprostone; Enzyme Inhibitors; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Lanthanum; Manganese; Nifedipine; Prostaglandin Antagonists; Thapsigargin; Verapamil | 1998 |
Effects of the selective cyclooxygenase-2 inhibitor nimesulide on vascular contractions in endothelium-denuded rat aorta.
Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Clonidine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelin-1; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Muscle Contraction; Nifedipine; Phenylephrine; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides | 1998 |
Effects of Crotalus durissus cascavella venom in the isolated rat kidney.
Topics: Animals; Cattle; Crotalid Venoms; Crotalus; Dexamethasone; Diuresis; Female; Glomerular Filtration Rate; In Vitro Techniques; Indomethacin; Kidney; Kidney Tubules, Proximal; Male; Nifedipine; Perfusion; Rats; Rats, Wistar; Renal Circulation; Sodium | 1998 |
Preventive strategies in endothelin-induced renal failure.
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antithrombins; Blood Pressure; Calcium Channel Blockers; Creatinine; Disease Models, Animal; Enalapril; Endothelins; Female; Hirudins; Indomethacin; Nifedipine; Renal Circulation; Swine; Vasoconstrictor Agents | 1998 |
Symptomatic hypocalcaemia in hypermagnesaemia-induced hypoparathyroidism, during magnesium tocolytic therapy--possible involvement of the calcium-sensing receptor.
Topics: Adult; Calcium; Female; Humans; Hypocalcemia; Hypoparathyroidism; Indomethacin; Magnesium; Nifedipine; Parathyroid Hormone; Pregnancy; Pregnancy Complications; Receptors, Calcium-Sensing; Receptors, Cell Surface; Tocolysis; Tocolytic Agents; Twins | 1999 |
Effects of K(+) channel inhibitors on relaxation induced by flufenamic and tolfenamic acids in guinea-pig trachea.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Calcium Channels, L-Type; Cromakalim; Dinoprost; Female; Flufenamic Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Nifedipine; ortho-Aminobenzoates; Potassium Channel Blockers; Potassium Channels; Trachea | 1999 |
Neuropeptide Y enhances potassium excretion by mechanisms distinct from those controlling sodium excretion.
Topics: Aldosterone; Animals; Bradykinin; Humans; Indomethacin; Losartan; Male; Neuropeptide Y; Nifedipine; Potassium; Rats; Rats, Wistar; Sodium | 2000 |
Search for best tocolytic for preterm labour.
Topics: Female; Humans; Indomethacin; Nifedipine; Obstetric Labor, Premature; Pregnancy; Randomized Controlled Trials as Topic; Ritodrine; Tocolytic Agents | 2000 |
Blockade of voltage-sensitive Ca(2+)-channels markedly diminishes nitric oxide- but not L-S-nitrosocysteine- or endothelium-dependent vasodilation in vivo.
Topics: Acetylcholine; Animals; Calcium Channel Blockers; Calcium Channels; Cysteine; Endothelium, Vascular; Hemodynamics; Hydrazines; Indomethacin; Male; Nifedipine; Nitric Oxide; Nitroprusside; Nitroso Compounds; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Sodium Chloride; Vasodilation; Vasodilator Agents | 2000 |
Signaling pathways involved in the A and B receptor-mediated cortisol secretagogue effect of endothelins in the human adrenal cortex.
Topics: Adenine; Androstadienes; Cells, Cultured; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Estrenes; Flavonoids; Humans; Hydrocortisone; Indomethacin; Naphthalenes; Nifedipine; Oligopeptides; Peptides, Cyclic; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Protein Kinase C; Pyrazoles; Pyrrolidinones; Receptors, Endothelin; Signal Transduction; Type C Phospholipases; Tyrphostins; Wortmannin; Zona Fasciculata; Zona Reticularis | 2001 |
Comparative study of the contractile activity evoked by ATP and diadenosine tetraphosphate in isolated rat urinary bladder.
Topics: Adenosine Triphosphate; Animals; Atropine; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Rats; Rats, Wistar; Theophylline; Urinary Bladder | 2002 |
Inhibitory actions of indomethacin on electrical and mechanical responses produced by nerve stimulation in circular smooth muscle of the guinea-pig gastric fundus.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitroarginine; Stimulation, Chemical | 2001 |
[Sensitivity of cationic polymer Eudragit RL to electrolytes and its effect on drug release from Eudragit RL matrix].
Topics: Chlorpheniramine; Delayed-Action Preparations; Electrolytes; Indomethacin; Microspheres; Nifedipine; Polymers; Polymethacrylic Acids | 1998 |
Mechanisms of proton-induced stimulation of CGRP release from rat antrum.
Topics: Animals; Calcitonin Gene-Related Peptide; Cholera Toxin; Hydrogen-Ion Concentration; Indomethacin; Male; Nifedipine; Pyloric Antrum; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Time Factors | 1995 |
Time course of the change in optic nerve head circulation after an acute increase in intraocular pressure.
Topics: Animals; Blood Circulation; Blood Flow Velocity; Calcium Channel Blockers; Indomethacin; Intraocular Pressure; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ocular Hypertension; Optic Disk; Parasympathectomy; Rabbits; Time Factors | 2003 |
Investigation of the physical stability of amorphous drug and drug/polymer melts using variable temperature solid state NMR.
Topics: Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Drug Stability; Indomethacin; Magnetic Resonance Spectroscopy; Nifedipine; Pharmaceutical Preparations; Polymers; Temperature; X-Ray Diffraction | 2003 |
Evidence for the mechanisms underlying the effects of pimaradienoic acid isolated from the roots of Viguiera arenaria on rat aorta.
Topics: Animals; Aorta, Thoracic; Asteraceae; Brazil; Diterpenes; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethanol; Indomethacin; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nifedipine; Oxadiazoles; Phenylephrine; Plant Extracts; Plant Roots; Quinoxalines; Rats; Rats, Wistar; Tetraethylammonium; Vasoconstriction; Vasodilation | 2004 |
Comparison of the Gordon-Taylor and Couchman-Karasz equations for prediction of the glass transition temperature of glass solutions of drug and polyvinylpyrrolidone prepared by melt extrusion.
Topics: Algorithms; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Differential Thermal Analysis; Humidity; Indomethacin; Nifedipine; Pharmaceutic Aids; Pharmaceutical Preparations; Povidone; Solubility; Temperature; Thermogravimetry; Tolbutamide | 2003 |
Time course of changes in optic nerve head circulation after acute reduction in intraocular pressure.
Topics: Acute Disease; Animals; Blood Circulation; Blood Circulation Time; Blood Flow Velocity; Calcium Channel Blockers; Enzyme Inhibitors; Indomethacin; Intraocular Pressure; Laser-Doppler Flowmetry; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ocular Hypotension; Optic Disk; Rabbits; Sympathetic Nervous System; Time Factors | 2005 |
Characterisation of indomethacin and nifedipine using variable-temperature solid-state NMR.
Topics: Carbon Isotopes; Indomethacin; Magnetic Resonance Spectroscopy; Molecular Structure; Nifedipine; Protons; Reference Standards; Temperature; X-Ray Diffraction | 2005 |
Effects of capsazepine on human small airway responsiveness unravel a novel class of bronchorelaxants.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Atropine; Bronchi; Bronchodilator Agents; Capsaicin; Cholinergic Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Histamine; Humans; In Vitro Techniques; Indomethacin; Leukotriene D4; Molecular Structure; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Peptides; Potassium Channels, Calcium-Activated; Propranolol; Prostaglandin D2; TRPV Cation Channels; Vasodilator Agents | 2007 |
Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle.
Topics: Amides; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cations; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Gadolinium; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Intracellular Signaling Peptides and Proteins; Ion Channels; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrobenzenes; Protein Serine-Threonine Kinases; Pyrazoles; Pyridines; rho-Associated Kinases; Simvastatin; Stress, Mechanical; Sulfonamides; Trachea | 2006 |
Antiphase oscillations of endothelium and smooth muscle [Ca2+]i in vasomotion of rat mesenteric small arteries.
Topics: Animals; Apamin; Calcium; Calcium Signaling; Charybdotoxin; Endothelial Cells; Endothelium, Vascular; In Vitro Techniques; Indoles; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Microscopy, Confocal; Models, Biological; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Norepinephrine; Potassium; Rats; Rats, Wistar; Ryanodine; Vasomotor System | 2007 |
Prediction of onset of crystallization from experimental relaxation times. II. Comparison between predicted and experimental onset times.
Topics: Algorithms; Calorimetry; Chemical Phenomena; Chemistry, Physical; Crystallization; Electrochemistry; Forecasting; Hydrogen Bonding; Indomethacin; Ketoconazole; Microscopy, Polarization; Models, Chemical; Models, Statistical; Nifedipine; Temperature; Thermodynamics | 2008 |
Effects of anethole and structural analogues on the contractility of rat isolated aorta: Involvement of voltage-dependent Ca2+-channels.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Aorta; Calcium; Calcium Channels; Cardiovascular Agents; Diltiazem; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavoring Agents; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; NG-Nitroarginine Methyl Ester; Nifedipine; Organ Culture Techniques; Oxidants; Phenylephrine; Rats; Rats, Wistar; Structure-Activity Relationship; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
A cost decision analysis of 4 tocolytic drugs.
Topics: Decision Trees; Drug Costs; Female; Humans; Indomethacin; Magnesium Sulfate; Nifedipine; Obstetric Labor, Premature; Pregnancy; Terbutaline; Tocolytic Agents | 2007 |
Vasorelaxant effect of a self-etch adhesive system through calcium antagonistic action.
Topics: 4-Aminopyridine; Animals; Aorta, Thoracic; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Dentin-Bonding Agents; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Glyburide; Indomethacin; Male; Materials Testing; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Nifedipine enhances the relaxant effects of cyclo-oxygenase inhibitors on the bovine ciliary muscle.
Topics: Animals; Calcium Channel Blockers; Cattle; Celecoxib; Ciliary Body; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Furans; Indomethacin; Muscle Relaxation; Nifedipine; Pyrazoles; Sulfonamides | 2008 |
Solubility of small-molecule crystals in polymers: D-mannitol in PVP, indomethacin in PVP/VA, and nifedipine in PVP/VA.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Indomethacin; Kinetics; Mannitol; Nifedipine; Povidone; Pyrrolidines; Reproducibility of Results; Solubility; Solvents; Technology, Pharmaceutical; Transition Temperature; Vinyl Compounds; Viscosity | 2009 |
Relaxing effects of Valeriana officinalis extracts on isolated human non-pregnant uterine muscle.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Atenolol; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Epinephrine; Female; Guinea Pigs; Humans; Hydrazines; Indenes; Indomethacin; Iridoids; Muscle Contraction; Muscle Relaxation; Myometrium; Nifedipine; Plant Extracts; Plant Roots; Premenopause; Sesquiterpenes; Valerates; Valerian | 2009 |
Preparation and pharmaceutical evaluation of new sustained-release capsule including starch-sponge matrix (SSM).
Topics: Adhesiveness; Animals; Capsules; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Electromagnetic Phenomena; Fluorescein; Freeze Drying; Indomethacin; Intestinal Absorption; Male; Nifedipine; Porosity; Rats; Rats, Wistar; Solubility; Starch | 2010 |
[Activity induced by androsterone and hemisuccinate of androsterone on perfusion pressure and vascular resistance].
Topics: Androsterone; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Coronary Vessels; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Flutamide; Heart; In Vitro Techniques; Indomethacin; Male; Nifedipine; Pregnenolone; Rats; Rats, Wistar; Vascular Resistance | 2009 |
Solubilities of crystalline drugs in polymers: an improved analytical method and comparison of solubilities of indomethacin and nifedipine in PVP, PVP/VA, and PVAc.
Topics: Calorimetry, Differential Scanning; Chemistry Techniques, Analytical; Crystallization; Indomethacin; Nifedipine; Polyvinyls; Povidone; Solubility; Transition Temperature | 2010 |
Effect of maternal body mass index on in vitro response to tocolytics in term myometrium.
Topics: Adult; Area Under Curve; Biopsy; Body Mass Index; Female; Humans; In Vitro Techniques; Indomethacin; Myometrium; Nifedipine; Pregnancy; Tocolytic Agents; Uterine Contraction | 2010 |
Nifedipine for the treatment of preterm labor in twin and singleton pregnancies.
Topics: Adult; Databases, Factual; Female; Gestational Age; Hospitals, University; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Israel; Male; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy, Twin; Survival Analysis; Tocolysis; Tocolytic Agents; Treatment Outcome | 2011 |
Vasodilatory effect of hydroxyethyl methacrylate and triethylene glycol dimethacrylate in rat aorta through calcium antagonistic action.
Topics: 4-Aminopyridine; Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Calcium Chloride; Composite Resins; Cyclooxygenase Inhibitors; Dental Materials; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Indomethacin; Male; Methacrylates; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase; Polyethylene Glycols; Polymethacrylic Acids; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Transducers; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
Changes induced by estradiol-ethylenediamine derivative on perfusion pressure and coronary resistance in isolated rat heart: L-type calcium channel.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Coronary Circulation; Cyclooxygenase Inhibitors; Estradiol; Estrogen Antagonists; Ethylenediamines; Female; In Vitro Techniques; Indomethacin; Metoprolol; Myocardium; Nifedipine; Prazosin; Rats; Rats, Wistar; Tamoxifen; Vascular Resistance | 2011 |
Successful management of a high-risk pregnancy with polyhydramnios, IUGR and recurrent pregnancy loss in a chronic renal failure patient: a case report.
Topics: Abortion, Habitual; Adult; Amniotic Fluid; Betamethasone; Birth Weight; Female; Fetal Growth Retardation; Humans; Indomethacin; Infant, Newborn; Kidney Failure, Chronic; Male; Nifedipine; Pregnancy; Pregnancy Complications; Renal Dialysis | 2011 |
Inhibition of uterine contractility with various tocolytics with and without progesterone: in vitro studies.
Topics: Adult; Female; Humans; Indomethacin; Magnesium Sulfate; Myometrium; Nifedipine; Obstetric Labor, Premature; Pinacidil; Pregnancy; Progesterone; Tocolytic Agents; Uterine Contraction | 2012 |
Ouabain stimulates atrial natriuretic peptide secretion via the endothelin-1/ET(B) receptor-mediated pathway in beating rabbit atria.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Natriuretic Factor; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin-1; Female; Heart; Heart Atria; In Vitro Techniques; Indomethacin; Male; Mitogen-Activated Protein Kinases; Nifedipine; Ouabain; Peptides, Cyclic; Rabbits; Radioimmunoassay; Receptor, Endothelin B; Sodium-Calcium Exchanger; Thiourea | 2012 |
Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension.
Topics: Animals; Anoctamin-1; Calcium Channel Blockers; Chloride Channel Agonists; Chloride Channels; Cyclooxygenase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indomethacin; Male; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; Niflumic Acid; Patch-Clamp Techniques; Pulmonary Artery; Pyrimidines; Rats; Rats, Wistar; Serotonin; Thiazoles | 2012 |
Lubiprostone stimulates small intestinal mucin release.
Topics: Alprostadil; Animals; Indomethacin; Intestine, Small; Lubiprostone; Male; Mice; Mice, Inbred C57BL; Mucins; Muscle, Smooth; Nifedipine | 2012 |
Development of qualitative and quantitative analysis methods in pharmaceutical application with new selective signal excitation methods for 13 C solid-state nuclear magnetic resonance using 1 H T1rho relaxation time.
Topics: Acetaminophen; Antipyrine; beta-Cyclodextrins; Caffeine; Carbon Isotopes; Chemistry, Pharmaceutical; Crystallization; Drug Combinations; Excipients; Indomethacin; Lactose; Magnetic Resonance Spectroscopy; Nifedipine; Pharmaceutical Preparations; Phenacetin; Povidone; Protons; Pyridones; Signal Processing, Computer-Assisted; Technology, Pharmaceutical | 2013 |
Effect of storage conditions on the recrystallization of drugs in solid dispersions with crospovidone.
Topics: Crystallization; Dipyridamole; Drug Carriers; Drug Stability; Hot Temperature; Humidity; Indomethacin; Nifedipine; Povidone | 2014 |
Arginine vasopressin, via activation of post-junctional V1 receptors, induces contractile effects in mouse distal colon.
Topics: Animals; Arginine Vasopressin; Atropine; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Colon; Cyclooxygenase Inhibitors; Enzyme Activation; Gastrointestinal Motility; In Vitro Techniques; Indomethacin; Male; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Phosphoinositide Phospholipase C; Receptors, Vasopressin; Signal Transduction; Tetrodotoxin | 2013 |
A method to evaluate the effect of contact with excipients on the surface crystallization of amorphous drugs.
Topics: Cellulose; Chemistry, Pharmaceutical; Crystallization; Excipients; Humidity; Indomethacin; Kinetics; Lactose; Mannitol; Nifedipine; Stearic Acids; Surface Properties; Tablets; Technology, Pharmaceutical; Water | 2014 |
In vitro relaxant and spasmolytic effects of essential oil of Pistacia integerrima Stewart ex Brandis Galls.
Topics: Acetylcholine; Animals; Calcium Channels; Calcium Chloride; Epinephrine; Guinea Pigs; Hexamethonium; Ileum; In Vitro Techniques; Indomethacin; Jejunum; Male; Mice; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nifedipine; Oils, Volatile; Parasympatholytics; Pistacia; Potassium; Rabbits; Receptors, Adrenergic, beta; Tetrodotoxin | 2015 |
Endothelium-Independent Vasorelaxant Effect of Ligusticum jeholense Root and Rhizoma on Rat Thoracic Aorta.
Topics: Animals; Aorta, Thoracic; Atropine; Calcium; Calcium Channels; Endothelium, Vascular; Extracellular Space; In Vitro Techniques; Indomethacin; Ligusticum; Male; Nifedipine; Phenylephrine; Plant Extracts; Plant Roots; Potassium Channels; Potassium Chloride; Rats; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2015 |
Effect of Tocolytics on Surfactant Secretion When Administered with Betamethasone: An in Vitro Study.
Topics: Betamethasone; Cell Line; Glucocorticoids; Humans; Indomethacin; Lecithins; Lung; Magnesium Sulfate; Nifedipine; Pulmonary Surfactant-Associated Protein B; Sphingomyelins; Tocolytic Agents | 2015 |
A novel formulation for solubility and content uniformity enhancement of poorly water-soluble drugs using highly-porous mannitol.
Topics: Adsorption; Chemistry, Pharmaceutical; Drug Liberation; Excipients; Indomethacin; Mannitol; Nifedipine; Porosity; Solubility | 2016 |
Drug delivery to the human and mouse uterus using immunoliposomes targeted to the oxytocin receptor.
Topics: Albuterol; Animals; Drug Delivery Systems; Female; Indomethacin; Liposomes; Mice; Myometrium; Nifedipine; Phenethylamines; Pregnancy; Premature Birth; Receptors, Oxytocin; Rolipram; Sulfonamides; Tissue Distribution; Uterine Contraction; Uterus | 2017 |
Magnetically Bioprinted Human Myometrial 3D Cell Rings as A Model for Uterine Contractility.
Topics: Bioprinting; Cells, Cultured; Female; Humans; Indomethacin; Magnets; Myometrium; Nifedipine; Precision Medicine; Uterine Contraction | 2017 |
Gelatin Nano-coating for Inhibiting Surface Crystallization of Amorphous Drugs.
Topics: Chemistry, Pharmaceutical; Crystallization; Excipients; Gelatin; Humans; Hydrophobic and Hydrophilic Interactions; Indomethacin; Kinetics; Microscopy; Nanostructures; Nifedipine; Particle Size; Phase Transition; Solubility; Surface Properties | 2018 |
Polyvinylpyrrolidone affects thermal stability of drugs in solid dispersions.
Topics: Drug Stability; Felodipine; Indomethacin; Nifedipine; Povidone; Thermogravimetry | 2018 |
Preparation of Amorphous Composite Particles of Drugs with Ursodeoxycholic Acid as Preclinical Formulations.
Topics: Calorimetry, Differential Scanning; Drug Compounding; Drug Evaluation, Preclinical; Drug Stability; Indomethacin; Naproxen; Nifedipine; Pharmaceutical Preparations; Solubility; Ursodeoxycholic Acid | 2019 |
Assessing the Potency of the Novel Tocolytics 2-APB, Glycyl-H-1152, and HC-067047 in Pregnant Human Myometrium.
Topics: Aminophylline; Female; Humans; Indomethacin; Infant, Newborn; Myometrium; Nifedipine; Pregnancy; Premature Birth; Rolipram; Tocolytic Agents; Uterine Contraction | 2023 |