nifedipine has been researched along with furosemide in 77 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (19.48) | 18.7374 |
| 1990's | 20 (25.97) | 18.2507 |
| 2000's | 17 (22.08) | 29.6817 |
| 2010's | 22 (28.57) | 24.3611 |
| 2020's | 3 (3.90) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF | 1 |
| Aoki, K; Kato, K; Kato, S; Kondo, S; Mochizuki, A; Takikawa, K; Yoshida, T | 1 |
| Bagni, B; Degli Uberti, EC; Ferlini, M; Montanari, L; Portaluppi, F; Vergnani, L | 1 |
| Cholewa, M; Dryjański, T; Gawor, Z; Górski, L; Kaczkowska-Marusik, E; Kuś, W; Markiewicz, K | 1 |
| Duława, J; Kokot, F; Kokot, M | 1 |
| Hirano, T; Kozaki, M; Oka, K; Tamaki, T; Toyoshima, Y | 1 |
| Belovezhdov, N; Kalburova, F; Robeva, R | 1 |
| Bechler-Lisińska, J; Cholewa, M; Górski, L; Markiewicz, K | 1 |
| Orynchak, MA | 2 |
| Feldshon, D; Gay, RG; Morrison, DA; Sampliner, RE | 1 |
| Bolla, G; Cuspidi, C; Gradnik, R; Leonetti, G; Rupoli, L; Sangiorgio, P; Zanchetti, A | 1 |
| Mimran, A; Ribstein, J | 2 |
| Bechler-Lisińska, J; Broks-Bratkowska, B; Cholewa, M; Dryjański, T; Gawor, Z; Górski, L; Markiewicz, K | 1 |
| Girchev, R; Piryova, B | 1 |
| Distler, A; Fritschka, E; Hoyer, J; Kribben, A; Philipp, T; Rothschild, M; Thiede, HM | 1 |
| Imhof, PR; Keller, R; Müller, P | 1 |
| Di Bona, GF; Ljung, B; Nordlander, M; Thorén, P; Yao, T | 1 |
| Hoitsma, AJ; Huysmans, FT; Koene, RA; Wetzels, JF; Wiltink, PG | 1 |
| Heckmann, U; Ottens, E; Zidek, W | 1 |
| Gradnik, R; Leonetti, G; Rupoli, L; Zanchetti, A | 1 |
| Ramos, OL; Ribeiro, AB; Saragoça, MA | 1 |
| Chan, JC; Cheung, CK; Cockram, CS; Law, LK; Nicholls, MG; Swaminathan, R | 1 |
| Górecki, A; Ignatowska-Switalska, H; Januszewicz, A; Kochanowski, J; Lapiński, M; Opolski, G; Stolarz, P; Słomka, K; Wocial, B | 1 |
| Hommel, E; Parving, HH; Rossing, P; Smidt, UM | 1 |
| Berne, C; Lind, L; Lithell, H; Pollare, T | 1 |
| Sharma, CD | 1 |
| Azukizawa, S; Kaneko, M; Kigoshi, T; Matsui, A; Morimoto, S; Nakano, S; Uchida, K | 1 |
| Angulo, J; Fernández-Alfonso, MS; Fuertes, E; González, R; Marín, J; Rodríguez-Martinez, MA; Sánchez-Ferrer, CF | 1 |
| Gangopadhyay, PK; Ghosh, SN; Guha, D; Munshi, AD; Saha, P | 1 |
| Jonkmann, JH; Schmidtke-Schrezenmeier, G; Tam, YK; van Brummelen, P; Weber, C | 1 |
| Goto, Y; Hashimoto, N; Takagi, Y | 1 |
| Ehmke, H; Just, A; Kirchheim, HR; Wittmann, U | 1 |
| Beaman, M; D'Souza, RJ; Hamilton-Wood, C; Nicholls, AJ; Pearson, ER | 1 |
| Ma, Y; Wang, W; Zhang, X | 1 |
| Kohno, M; Masugata, H; Ohmori, K; Ohnishi, K; Takagi, Y; Wada, Y; Yukiiri, K | 1 |
| Gehl, HB; Härtel, C; Schilling, S; Sperner, J | 1 |
| Ewert, R; Felix, S; Opitz, C; Schlag, K; Wensel, R | 1 |
| Ayazifar, M; Murphy, MA | 1 |
| Füessl, HS | 1 |
| Dalmia, S; Deka, D; Gupta, N; Mittal, S | 1 |
| Araki, M; Inui, T; Kubota, T; Miyamoto, M; Mori, Y; Nimura, Y; Takenaka, H; Watanabe, M | 1 |
| Biswas, D; Ghosh, M; Mukherjee, A | 1 |
| Ali Khan, MA; Hasan, N; Sabir, MS | 1 |
| Ahn, A; Ho, CH; Im, D; Laster, M | 1 |
| Alashi, Y; Biliaminu, SA; Owoyele, BV; Oyewole, AL | 1 |
| Aarons, L; Darwich, A; Dressman, J; Hansmann, S; Margolskee, A | 1 |
| Perivela, L; Raghavan, SS; Veena, P | 1 |
| Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V | 1 |
| Attakora, J; Donkoh, IE; Ephraim, RKD; Essuman, G; Okyere, I; Okyere, P; Serwaa, D | 1 |
3 review(s) available for nifedipine and furosemide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells | 2022 |
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease; Female; Fetal Growth Retardation; Furosemide; Gestational Age; Humans; Hypertension; Incidence; Infant, Small for Gestational Age; Ketanserin; Methyldopa; Network Meta-Analysis; Nifedipine; Perinatal Death; Pindolol; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Premature Birth; Severity of Illness Index | 2020 |
15 trial(s) available for nifedipine and furosemide
| Article | Year |
|---|---|
[Results of conventional treatment of severe congestive heart failure with vasodilators].
Topics: Adult; Aged; Captopril; Digoxin; Drug Administration Schedule; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Time Factors; Vasodilator Agents | 1992 |
[Effects of furosemide, propranolol and nifedipine on urinary excretion of Tamm-Horsfall protein in patients with arterial hypertension].
Topics: Adult; Circadian Rhythm; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Mucoproteins; Nifedipine; Propranolol; Time Factors; Uromodulin | 1992 |
[Effect of vasodilator agents on the character and incidence of cardiac arrhythmia in chronic heart failure].
Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Atrial Fibrillation; Captopril; Cardiac Output; Coronary Disease; Digoxin; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Furosemide; Heart Block; Heart Failure; Heart Valve Diseases; Heart Ventricles; Humans; Isosorbide; Male; Middle Aged; Nifedipine; Tachycardia; Vasodilator Agents | 1990 |
[Evaluation of the effect of nifedipine in patients with chronic congestive heart failure].
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Digoxin; Diuresis; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Time Factors | 1989 |
Pharmacological profiling of cardiovascular agents in healthy volunteers by means of non-invasive methods.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Angiotensin II; Blood Pressure; Cardiography, Impedance; Cardiovascular Agents; Furosemide; Heart Rate; Humans; Male; Nifedipine; Nitroglycerin; Phentolamine; Systole | 1987 |
Diuretic and natriuretic effects of nifedipine in healthy persons.
Topics: Adult; Creatinine; Diuresis; Female; Furosemide; Hemodynamics; Humans; Lithium; Male; Natriuresis; Nifedipine; Potassium; Reference Values; Sodium | 1988 |
Effects of a low-sodium diet on antihypertensive and natriuretic responses to acute administration of nifedipine.
Topics: Adult; Aged; Blood Pressure; Combined Modality Therapy; Diet, Sodium-Restricted; Double-Blind Method; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Natriuresis; Nifedipine; Random Allocation; Time Factors | 1987 |
[Immediate and long-term antihypertensive effects of nifedipine in mild and moderate hypertension].
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Furosemide; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1985 |
Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM.
Topics: Albuminuria; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Furosemide; Glycated Hemoglobin; Humans; Hypertension; Indapamide; Nifedipine; Placebos; Potassium; Regression Analysis; Renin; Sodium; Time Factors | 1995 |
Angiotensin-converting enzyme inhibition in diabetic nephropathy: ten years' experience.
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Bendroflumethiazide; Blood Pressure; Captopril; Cholesterol; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Drug Therapy, Combination; Female; Furosemide; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Hypertension; Kidney; Least-Squares Analysis; Male; Middle Aged; Nifedipine; Prognosis; Prospective Studies; Regression Analysis | 1995 |
Metabolic effects of anti-hypertensive treatment with nifedipine or furosemide: a double-blind, cross-over study.
Topics: Aged; Analysis of Variance; Body Weight; Cross-Over Studies; Double-Blind Method; Female; Furosemide; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Heart Rate; Humans; Hypertension; Lipoproteins; Male; Middle Aged; Nifedipine | 1995 |
Effect of the lipase inhibitor orlistat on the pharmacokinetics of four different antihypertensive drugs in healthy volunteers.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Captopril; Chromatography, High Pressure Liquid; Cross-Over Studies; Diuretics; Drug Therapy, Combination; Enzyme Inhibitors; Female; Furosemide; Humans; Hypertension; Lactones; Male; Nifedipine; Orlistat | 1996 |
[Low-concentration nitrous oxide inhalation in the treatment of high-altitude pulmonary edema].
Topics: Administration, Inhalation; Adult; Altitude Sickness; Aminophylline; Dexamethasone; Drug Therapy, Combination; Furosemide; Humans; Male; Nifedipine; Nitrous Oxide; Oxygen; Pulmonary Edema | 1998 |
Influence of the angiotensin II receptor antagonist losartan on diuretic-induced metabolic effects in elderly hypertensive patients: comparison with a calcium channel blocker.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension; Losartan; Male; Nifedipine; Trichlormethiazide | 2001 |
Furosemide in postpartum management of severe preeclampsia: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Nifedipine; Postpartum Period; Pre-Eclampsia; Pregnancy; Puerperal Disorders; Treatment Outcome; Young Adult | 2017 |
59 other study(ies) available for nifedipine and furosemide
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Antihypertensive effect of cardiovascular Ca2+-antagonist in hypertensive patients in the absence and presence of beta-adrenergic blockade.
Topics: Adult; Blood Pressure; Calcium; Cardiac Output; Female; Furosemide; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Propranolol; Pyridines; Renin | 1978 |
Differences in blood pressure regulation of congestive heart failure, before and after treatment, correlate with changes in the circulating pattern of atrial natriuretic peptide.
Topics: Aged; Atrial Natriuretic Factor; Blood Pressure; Cardiotonic Agents; Digoxin; Drug Therapy, Combination; Female; Furosemide; Gated Blood-Pool Imaging; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Nifedipine; Nitrates; Ventricular Function, Left | 1992 |
Promotion of lymphocyte blastogenesis by hemodialysate of chronic renal failure.
Topics: Allopurinol; Anabolic Agents; Androstanols; Calcitriol; Cells, Cultured; Concanavalin A; Creatinine; DNA Replication; Female; Furosemide; Humans; Kidney Failure, Chronic; Lectins; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Nifedipine; Reference Values; Renal Dialysis; Thymidine; Time Factors | 1992 |
Gordon's syndrome--hypertension and hyperkalemia associated with normal glomerular filtration rate.
Topics: Adult; Furosemide; Glomerular Filtration Rate; Humans; Hyperkalemia; Hypertension; Male; Nifedipine; Syndrome | 1992 |
[Evaluation of the effectiveness of calcium antagonists combined with digoxin and furosemide in hypertension complicated by circulatory insufficiency in elderly patients].
Topics: Aged; Digoxin; Drug Therapy, Combination; Furosemide; Heart Failure; Hemodynamics; Humans; Hypertension; Nifedipine | 1990 |
Severe pulmonary hypertension in a patient with Whipple's disease.
Topics: Drug Combinations; Furosemide; Heart Failure; Heart Murmurs; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nifedipine; Oxygen; Penicillins; Pulmonary Wedge Pressure; Recurrence; Stroke Volume; Sulfamethoxazole; Tetracycline; Trimethoprim; Whipple Disease | 1985 |
Effects of different sodium intakes on the antihypertensive and renal effects of single oral doses of nifedipine in hypertensive patients.
Topics: Administration, Oral; Adult; Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Furosemide; Heart Rate; Humans; Hypertension; Kidney; Middle Aged; Nifedipine; Renin; Sodium | 1987 |
Effect of chronic nifedipine in patients inadequately controlled by a converting enzyme inhibitor and a diuretic.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Creatinine; Dipeptides; Drug Resistance; Enalapril; Female; Furosemide; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Potassium; Substance Withdrawal Syndrome | 1985 |
[The efficacy of calcium antagonists in circulatory failure in elderly patients with hypertension].
Topics: Aged; Calcium Channel Blockers; Digoxin; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Factors; Verapamil | 1989 |
Potentiation of the diuretic and natriuretic effect of furosemide by the calcium antagonist nifedipine.
Topics: Animals; Blood Pressure; Diuresis; Drug Synergism; Furosemide; Male; Natriuresis; Nifedipine; Rats; Rats, Inbred Strains; Urodynamics | 1989 |
Regulation of alpha 2-adrenoceptor density in normotensive and hypertensive man.
Topics: Adenylyl Cyclases; Blood Platelets; Clonidine; Furosemide; Humans; Hypertension; Male; Nifedipine; Norepinephrine; Receptors, Adrenergic, alpha | 1987 |
Renal and cardiovascular effects of acute and chronic administration of felodipine to SHR.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Felodipine; Furosemide; Heart Rate; Hemodynamics; Kidney; Male; Minoxidil; Nifedipine; Rats; Rats, Inbred SHR; Renal Circulation; Sodium; Sympathetic Nervous System | 1985 |
Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Enalapril; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Potassium | 1986 |
The effect of antihypertensive treatment on the circulating hypertensive factor in the spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Cross Circulation; Furosemide; Hypertension; Male; Methyldopa; Nifedipine; Propranolol; Rats; Rats, Inbred SHR | 1987 |
Elevated plasma atrial natriuretic peptide concentrations in hypertensive patients with acute myocardial infarction.
Topics: Acebutolol; Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Cardiac Output, Low; Creatine Kinase; Creatinine; Echocardiography; Female; Furosemide; Heart Atria; Heart Ventricles; Humans; Hypertension; Isoenzymes; Male; Metoprolol; Middle Aged; Myocardial Infarction; Nifedipine; Potassium; Sodium | 1995 |
Atrial fibrillation with hypertensive crisis.
Topics: Atrial Fibrillation; Electrocardiography; Furosemide; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1994 |
Reversible hyperkalemia during antihypertensive therapy in a hypertensive diabetic patient with latent hypoaldosteronism and mild renal failure.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Enalapril; Furosemide; Humans; Hyperaldosteronism; Hyperkalemia; Hypertension; Kidney Failure, Chronic; Male; Nifedipine | 1994 |
Pressure-induced contraction of the juxtamedullary afferent arterioles in spontaneously hypertensive rats.
Topics: Animals; Arterioles; Blood Pressure; Furosemide; In Vitro Techniques; Kidney Medulla; Muscle Contraction; Muscle, Smooth, Vascular; Nephrons; Nifedipine; Norepinephrine; Perfusion; Pressure; Rats; Rats, Inbred SHR; Regional Blood Flow; Renal Circulation; Serotonin | 1994 |
Spontaneous cerebellar haematoma treated conservatively.
Topics: Brain Diseases; Furosemide; Hematoma; Humans; Male; Middle Aged; Nifedipine | 1993 |
Haemodynamic ischaemia in paediatric moyamoya disease associated with renovascular hypertension.
Topics: Antihypertensive Agents; Brain; Cerebral Angiography; Cerebral Cortex; Cerebral Infarction; Cerebral Revascularization; Child; Drug Therapy, Combination; Enalapril; Female; Furosemide; Hemodynamics; Humans; Hypertension, Renovascular; Moyamoya Disease; Nifedipine; Regional Blood Flow; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 1997 |
Autoregulation of renal blood flow in the conscious dog and the contribution of the tubuloglomerular feedback.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Calcium Channel Blockers; Cholinergic Antagonists; Diuretics; Dogs; Furosemide; Heart Rate; Hexamethonium; Homeostasis; Kidney; Kidney Glomerulus; Kidney Tubules; Nifedipine; Renal Circulation; Vascular Resistance | 1998 |
Hypertensive encephalopathy and nephrotic syndrome: a possible link?
Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Azathioprine; Brain Diseases; Calcium Channel Blockers; Diuretics; Doxazosin; Female; Furosemide; Headache; Humans; Hypertension; Immunosuppressive Agents; Magnetic Resonance Imaging; Middle Aged; Nephrotic Syndrome; Nifedipine; Prednisolone; Seizures; Visual Acuity | 1999 |
MRI findings in acute hypertensive encephalopathy.
Topics: Acute Disease; Adolescent; Cerebral Cortex; Diuretics; Electroencephalography; Epilepsy, Tonic-Clonic; Furosemide; Humans; Hypertensive Encephalopathy; Magnetic Resonance Imaging; Male; Nifedipine; Vasodilator Agents | 2003 |
[Pulmonary hypertension in hereditary haemorrhagic teleangiectasia (Rendu-Osler-Weber disease). Progression over 10 years].
Topics: Anticoagulants; Antihypertensive Agents; Bosentan; Calcium Channel Blockers; Diuretics; Endothelin Receptor Antagonists; Epistaxis; Epoprostenol; Female; Furosemide; Humans; Hypertension, Pulmonary; Iloprost; Middle Aged; Nifedipine; Pedigree; Phenprocoumon; Pyridines; Sulfonamides; Telangiectasia, Hereditary Hemorrhagic; Treatment Failure; Vasodilator Agents | 2005 |
Permanent visual deficits secondary to the HELLP syndrome.
Topics: Adult; Blood Pressure; Brain Infarction; Drug Therapy, Combination; Eclampsia; Female; Furosemide; HELLP Syndrome; Hemianopsia; Humans; Intracranial Hemorrhages; Labetalol; Magnetic Resonance Imaging; Mannitol; Nifedipine; Occipital Lobe; Pregnancy; Retinal Hemorrhage; Visual Acuity | 2005 |
[Emergency checklist in hypertensive crisis].
Topics: Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Clonidine; Diuretics; Emergencies; Female; Furosemide; Hospitalization; Humans; Hypertension; Male; Medical History Taking; Nifedipine; Nitrendipine; Pregnancy; Vasodilator Agents | 2006 |
Successful maternal and fetal outcome in a pregnancy with type V Takayasu's aortoarteritis.
Topics: Adult; Antihypertensive Agents; Arterial Occlusive Diseases; Calcium Channel Blockers; Diuretics; Female; Furosemide; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Live Birth; Male; Methyldopa; Mitral Valve Insufficiency; Nifedipine; Pregnancy; Pregnancy Complications, Cardiovascular; Takayasu Arteritis; Ventricular Dysfunction, Left | 2008 |
Ca(2+) regulation of endocochlear potential in marginal cells.
Topics: Amiloride; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cochlea; Egtazic Acid; Endolymph; Epithelial Sodium Channels; Evoked Potentials, Auditory; Furosemide; Guinea Pigs; Imidazoles; Nifedipine; Sodium Channel Blockers; Sodium Potassium Chloride Symporter Inhibitors; Thapsigargin; TRPC Cation Channels | 2009 |
High-altitude medicines: a short-term genotoxicity study.
Topics: Acetazolamide; Adult; Altitude Sickness; Analysis of Variance; Cell Survival; Cells, Cultured; Comet Assay; Dexamethasone; DNA; DNA Damage; Furosemide; Humans; Ibuprofen; Lymphocytes; Male; Mutagenicity Tests; Nifedipine; Theophylline | 2010 |
Hypertensive encephalopathy: a rare presentation of Williams-Beuren Syndrome.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Child, Preschool; Diuretics; Enalapril; Furosemide; GABA Modulators; Humans; Hypertensive Encephalopathy; Male; Midazolam; Nifedipine; Williams Syndrome | 2011 |
A 12-year-old boy with dyspnea, hypertension, hematuria, and proteinuria.
Topics: Child; Diagnosis, Differential; Dyspnea; Furosemide; Glomerulonephritis; Hematuria; Humans; Hypertension; Male; Nifedipine; Proteinuria | 2015 |
Effect of taurine and caffeine on plasma c-reactive protein and calcium in Wistar rats.
Topics: Animals; Biomarkers; C-Reactive Protein; Caffeine; Calcium; Calcium Channel Blockers; Central Nervous System Stimulants; Furosemide; Nifedipine; Rats, Wistar; Sodium Potassium Chloride Symporter Inhibitors; Taurine | 2015 |
Forecasting oral absorption across biopharmaceutics classification system classes with physiologically based pharmacokinetic models.
Topics: Administration, Intravenous; Administration, Oral; Animals; Biological Availability; Biopharmaceutics; Biotransformation; Bisoprolol; Cimetidine; Computer Simulation; Drug Compounding; Forecasting; Furosemide; Gastrointestinal Absorption; Humans; Models, Biological; Nifedipine; Permeability; Reproducibility of Results | 2016 |
Conservative therapy is associated with worse clinical features and biochemical derangements than renal replacement therapy: a retrospective study in Kumasi, Ghana.
Topics: Adult; Aspirin; Bisoprolol; Conservative Treatment; Furosemide; Ghana; Humans; Irbesartan; Kidney Failure, Chronic; Lisinopril; Metformin; Middle Aged; Nifedipine; Ranitidine; Renal Replacement Therapy; Retrospective Studies; Sodium | 2022 |