nifedipine has been researched along with fluorouracil in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (11.54) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (42.31) | 29.6817 |
| 2010's | 11 (42.31) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bruckner, HW; Oleksowicz, L | 1 |
| Bondì, F; Di Gregorio, L; Iacona, MA; Mancuso, L; Marchì, S | 1 |
| Ezaki, T; Miyagi, N; Nakatani, K; Sakamoto, K; Sugizaki, T | 1 |
| Kawaguchi, Y; Nagayama, S; Shindo, T; Yoshisue, K | 1 |
| Friedlander, ML; Kohn, EC; Qu, XJ; Yang, JL; Yu, Y | 1 |
| Benomar, S; Benzekri, L; Boutayeb, S; Errihani, H; Hassam, B; Senouci, K | 1 |
| Chakrabarty, S; Hu, X; Liu, G; Premkumar, L | 1 |
| Cho, WH; Choi, SK; Kim, SB; Kim, SM; Kwak, CH; Lee, B; Sir, JJ | 1 |
| Bekaii-Saab, T; Blazer, M; Gulati, M; Reardon, J; Vargo, CA | 1 |
| Hashimoto, M; Matsumura, T; Nakamura-Ishizu, A; Suda, T; Umemoto, T | 1 |
| Hirata, T; Ishii, T; Kokuba, S; Nakamura, K; Shiohira, H; Tayag, JCS | 1 |
1 review(s) available for nifedipine and fluorouracil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
25 other study(ies) available for nifedipine and fluorouracil
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Prophylaxis of 5-fluorouracil-induced coronary vasospasm with calcium channel blockers.
Topics: Aged; Angina Pectoris; Coronary Vasospasm; Female; Fluorouracil; Humans; Nifedipine | 1988 |
Cardiac toxicity of 5-fluorouracil. Report of a case of spontaneous angina.
Topics: Angina Pectoris; Colonic Neoplasms; Electrocardiography; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Nifedipine | 1986 |
[Effects of combination therapy of carmofur and nicardipine of human gastric cancer in nude mice].
Topics: Animals; Cell Line; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nicardipine; Nifedipine; Stomach Neoplasms | 1985 |
Effects of 5-fluorouracil on the drug-metabolizing enzymes of the small intestine and the consequent drug interaction with nifedipine in rats.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Biotransformation; Calcium Channel Blockers; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Fluorouracil; Glucuronosyltransferase; Glutathione Transferase; Immunoblotting; Intestinal Mucosa; Intestine, Small; Male; Microsomes; NADPH-Ferrihemoprotein Reductase; Nifedipine; Oxonic Acid; Pentosyltransferases; Pyridines; Rats; Rats, Inbred Strains; Tegafur | 2001 |
Selective sensitivity to carboxyamidotriazole by human tumor cell lines with DNA mismatch repair deficiency.
Topics: Antineoplastic Agents; Apoptosis; Calcium Channel Blockers; Cell Cycle; Cell Line, Tumor; Chromosomes, Human; Colonic Neoplasms; Colorimetry; DNA Mismatch Repair; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Male; Neoplasm Invasiveness; Neoplasms; Nifedipine; Ovarian Neoplasms; Prostatic Neoplasms; Transfection; Triazoles; Urinary Bladder Neoplasms | 2008 |
[Limited 5-fluorouracil-induced systemic scleroderma].
Topics: Adult; Antimetabolites, Antineoplastic; Calcium Channel Blockers; Colectomy; Colonic Neoplasms; Female; Fluorouracil; Humans; Nifedipine; Scleroderma, Systemic; Treatment Outcome | 2009 |
Nifedipine synergizes with calcium in activating the calcium sensing receptor, suppressing the expression of thymidylate synthase and survivin and promoting sensitivity to fluorouracil in human colon carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Calcium; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; GTP-Binding Proteins; Humans; Inhibitor of Apoptosis Proteins; Nifedipine; Receptors, Calcium-Sensing; RNA Interference; RNA, Small Interfering; Survivin; Thymidylate Synthase | 2011 |
A case of severe coronary spasm associated with 5-fluorouracil chemotherapy.
Topics: Aged, 80 and over; Angina Pectoris; Antineoplastic Combined Chemotherapy Protocols; Calcium Channel Blockers; Colonic Neoplasms; Coronary Angiography; Coronary Vasospasm; Drug-Eluting Stents; Electrocardiography; Fluorouracil; Humans; Leucovorin; Male; Nifedipine; Nitroglycerin; Organoplatinum Compounds; Percutaneous Coronary Intervention; Recurrence; Severity of Illness Index; Treatment Outcome; Vasodilator Agents | 2012 |
Successful Completion of Adjuvant Chemotherapy in a Patient With Colon Cancer Experiencing 5-Fluorouracil-Induced Cardiac Vasospasm.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cardiotoxicity; Chemotherapy, Adjuvant; Colonic Neoplasms; Coronary Vasospasm; Diltiazem; Female; Fluorouracil; Humans; Leucovorin; Middle Aged; Nifedipine; Organoplatinum Compounds; Vasodilator Agents | 2016 |
Ca
Topics: Adenosine; Animals; Bone Marrow Cells; Calcium; Calcium Channel Blockers; Cell Cycle; Cell Division; Down-Regulation; Fluorouracil; Hematopoietic Stem Cells; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mitochondria; Nifedipine; Up-Regulation | 2018 |
Effects of 5-fluorouracil Co-administration on Blood Pressure in Patients Maintained on Antihypertensives: a Retrospective Case Series.
Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Fluorouracil; Humans; Hypertension; Nifedipine; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2023 |