nifedipine has been researched along with flunarizine in 113 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 42 (37.17) | 18.7374 |
1990's | 45 (39.82) | 18.2507 |
2000's | 13 (11.50) | 29.6817 |
2010's | 12 (10.62) | 24.3611 |
2020's | 1 (0.88) | 2.80 |
Authors | Studies |
---|---|
Barrett, RJ; Johnson, CP; Proakis, AG; Shanklin, JR | 1 |
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Janis, RA; Triggle, DJ | 1 |
Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Brouillette, WJ; Brown, GB; Zha, C | 1 |
Bennis, K; Ducki, S; Lesage, F; Vivier, D | 1 |
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN | 1 |
Dong, G; Liu, N; Sheng, C; Tu, J; Wang, Y | 1 |
Dantchev, N; Popov, P; Staneva-Stoytcheva, D | 1 |
Montastruc, JL; Senard, JM | 1 |
Berga, P; Furman, BL; Gristwood, RW; Jauregui, J; Llenas, J | 1 |
D'Ancona, S; Mazzo, M; Pea, F | 1 |
Kamei, J; Kasuya, Y | 1 |
Masukawa, Y; Misawa, M; Shiozaki, Y; Suzuki, T | 1 |
Danchev, N; Popov, P; Staneva-Stoytcheva, D | 1 |
Karpinski, E; Pang, PK; Wang, R; Wu, LY | 1 |
Deyo, RA; Disterhoft, JF; Thompson, LT | 1 |
Bleehen, NM; Honess, DJ | 1 |
Karpinski, E; Liu, QY; Pang, PK; Rao, MR | 1 |
Ivanova, E; Popova, J; Staneva-Stoytcheva, D; Tosheva, T | 1 |
Fabrègues, E; John, GW; Kamal, M; Massingham, R | 1 |
Pang, CC; Waite, RP; Walker, MJ | 1 |
Krishna, G; Kutty, RK; Santostasi, G | 1 |
Nebel, U; Wermelskirchen, D; Wilffert, B; Wirth, A | 1 |
Alov, P; Mutafova-Yambolieva, V; Popova, J; Staneva-Stoytcheva, D | 1 |
Locher, R; Sachinidis, A; Steiner, A; Vetter, W | 1 |
Casas Parera, I; Fernandez Pardal, M; Gatto, M; Lekhuniec, E; Mangone, C; Micheli, F; Pikielny, R | 1 |
Mutafova, V; Popova, J; Staneva-Stoytcheva, D | 1 |
Gaggi, R; Gianni, AM | 1 |
Carpenter, CL; Greenberg, DA; Messing, RO | 2 |
Greenberg, DA | 1 |
Traber, J; Van Rooijen, LA | 1 |
Mayerhofer, S | 1 |
Blanco, I; Brandner, R; Rodriguez, J; Rodriguez, R; Sabrià, J; Toledo, A | 1 |
Duhm, J; Engelmann, B | 1 |
Hirst, DG; Wood, PJ | 2 |
Al Osachie, I; Egleme, C; Godfraind, T | 1 |
Edvinsson, L; Ikomi-Kumm, J; Monti, M | 1 |
Gouw, MA; van Zwieten, PA; Wilffert, B | 1 |
Godfraind, T; Morel, N | 1 |
Cruz, LJ; Olivera, BM | 1 |
Dolin, SJ; Little, HJ | 1 |
Aragno, R; Bettini, V; De Bartolomeis, L; Fabro, P; Munari, L; Ton, P | 1 |
Schwartzkroin, PA; Taube, JS | 1 |
Fujiwara, T; Ishimatsu, T; Itoh, T; Kanmura, Y; Satoh, S | 1 |
Baky, S; Nademanee, K; Singh, BN | 1 |
Chiang, DH; Wei, JW | 1 |
Agnoli, A | 1 |
Koch, P; Nebel, U; Peters, T; Wermelskirchen, D; Wilffert, B; Wilhelm, D | 1 |
Fernandez Pardal, J; Fernandez Pardal, M; Micheli, F | 1 |
Fitzpatrick, JM; Leahy, AL; Wait, RB | 1 |
Harrison, GG; Morrell, DF; Wright, IG | 1 |
Auguet, M; Clostre, F; DeFeudis, FV; Delaflotte, S | 1 |
Grebb, JA | 1 |
Henry, PD | 1 |
Solomon, GD | 1 |
Capecchi, PL; Ceccatelli, L; Di Perri, T; Laghi Pasini, F; Orrico, A; Pasqui, AL | 1 |
Borgers, M; Donck, LV; Pauwels, PJ; Vandeplassche, G | 1 |
Boccuni, M; Cangi, F; Fanciullacci, M; Fusco, BM; Gatto, G; Marabini, S; Pietrini, U | 1 |
Bishop, CM; Capetola, RJ; Hedli, CC; Levinson, SL; Ritchie, DM; Sierchio, JN | 1 |
Beatty, DA; Colker, JE; Fairhurst, AS; Thayer, SA | 1 |
Oriowo, MA | 1 |
Clincke, GH; Wauquier, A | 1 |
Miller, WC; Moore, JB | 1 |
Bolger, GT; Gengo, P; Janis, RA; Klockowski, R; Luchowski, E; Siegel, H; Triggle, AM; Triggle, DJ | 1 |
Van Nueten, JM; Vanhoutte, PM | 1 |
Flaim, SF; Zelis, R | 1 |
Abbe, R; Appel, SH; Bostwick, JR | 1 |
Shibata, S; Shindou, T; Tominaga, K; Watanabe, S | 1 |
Calder, L; Clikeman, J; Finnegan, KT; Karler, R; Wei, S | 1 |
Castelletti, CM; De Ponti, F; Frigo, GM; Lecchini, S; Marcoli, M; Marino, F | 1 |
Wessely, P; Wöber-Bingöl, C | 1 |
Edamatsu, R; Hiramatsu, M; Mori, A; Mori, I; Ohba, S | 1 |
Asai, Y; Kohno, Y; Nakashima, M; Uematsu, T; Umemura, K | 1 |
Misawa, M; Mizoguchi, H; Suzuki, T; Yoshiike, M | 1 |
Lamsudin, R; Sadjimin, T | 1 |
Floersheim, GL | 1 |
Pleuvry, BJ; Rodger, C | 1 |
Etou, K; Hirano, M; Kuroki, T; Tashiro, N; Tatebayashi, Y | 1 |
Nilles, R | 1 |
Fukui, M; Ikezaki, K; Matsukado, K; Nomura, T | 1 |
Borowicz, K; Czuczwar, SJ; Gasior, M; Kleinrok, Z; Starownik, R | 2 |
Carvajal, A; Dueñas, A; Fernández de la Gándara, F; Maroto, M; Nieto, A; Velasco, A | 1 |
Hori, Y; Matsumiya, T; Takeda, H; Tsuji, M | 1 |
Akaike, N; Ishibashi, H; Murai, Y | 1 |
Barbieri, A; Bianchi, L; Boselli, C; Grana, E | 1 |
Honegger, P; Pardo, B | 1 |
Boyadjieva, NI; De, A; Sarkar, DK | 1 |
Higuchi, H; Hishikawa, Y; Shimizu, T; Takahashi, H; Yoshimoto, M | 1 |
Holman, NA; Mamic, TM; Monteith, GR; Roberts-Thomson, SJ | 1 |
Kostyuk, PG; Shuba, YM; Zhuravleva, SO | 1 |
Armando, I; Belforte, JE; Buño, W; Magariños-Azcone, C; Pazo, JH | 1 |
Jensen, JB; Lund, TM; Pickering, DS; Schousboe, A; Timmermann, DB | 1 |
Baillie, N; Chaisewikul, R; Marson, AG | 1 |
Chidlow, G; Cupido, A; Melena, J; Osborne, NN; Wood, JP | 1 |
Borowicz, KK; Czuczwar, SJ; Kleinrok, Z; Porebiak, J; Swiader, M | 1 |
Barreto, KP; Pessoa-Pureur, R; Royer, C; Silva, FR; Zamoner, A | 1 |
Clark, J; Cull, A; Klose, MK; Mercier, AJ; Milakovic, M | 1 |
Kitano, H; Shinohara, H; Zakir Hossain, SM | 1 |
Phillips, MF; Quinlivan, R | 1 |
Ishii, K; Mori, A; Nakahara, T; Noguchi, M; Sakamoto, K | 1 |
Amobi, N; Guillebaud, J; Smith, CH | 1 |
An Haack, K; Bennett, MJ; Li, H; Narayan, SB; Tan, L; Warnock, A | 1 |
Gieseg, SP; Whiteman, M; Yang, YT | 1 |
Capuano, V; Ferron, L; Renaud, JF; Ruchon, Y; Sankhe, S | 1 |
Hasan, M; Marson, AG; Pulman, J | 1 |
Aamodt, EJ; Dwyer, DS; Kasap, M; Sagrera, CE | 1 |
12 review(s) available for nifedipine and flunarizine
Article | Year |
---|---|
New developments in Ca2+ channel antagonists.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Electrophysiology; Heart; Humans; Ion Channels; Muscle Relaxation; Muscle, Smooth; Potassium; Sodium; Structure-Activity Relationship; Substrate Specificity | 1983 |
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship | 2016 |
Emerging New Targets for the Treatment of Resistant Fungal Infections.
Topics: Antifungal Agents; Drug Resistance, Fungal; Humans; Molecular Targeted Therapy; Mycoses | 2018 |
[Calcium channel blockers and prevention of migraine].
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Diltiazem; Flunarizine; Humans; Migraine Disorders; Nifedipine; Nimodipine; Verapamil | 1992 |
Calcium channel antagonists and the treatment of migraine.
Topics: Calcium; Calcium Channel Blockers; Cinnarizine; Diltiazem; Flunarizine; Humans; Ion Channels; Kinetics; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil | 1986 |
Second-generation calcium antagonists: search for greater selectivity and versatility.
Topics: Animals; Bepridil; Calcium Channel Blockers; Cinnarizine; Electrophysiology; Flunarizine; Heart; Humans; Lidoflazine; Muscle, Smooth, Vascular; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyrrolidines; Structure-Activity Relationship | 1985 |
Atherosclerosis, calcium, and calcium antagonists.
Topics: Animals; Aorta; Arteries; Arteriosclerosis; Calcinosis; Calcium; Calcium Channel Blockers; Cell Survival; Cholesterol, Dietary; Cinnarizine; Diltiazem; Flunarizine; Humans; Membrane Lipids; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Propranolol; Rabbits; Verapamil | 1985 |
Comparative efficacy of calcium antagonist drugs in the prophylaxis of migraine.
Topics: Calcium Channel Blockers; Cinnarizine; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Flunarizine; Humans; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil | 1985 |
[Calcium channel blockers in therapy of neurologic diseases].
Topics: Brain Ischemia; Calcium Channel Blockers; Cluster Headache; Flunarizine; Humans; Migraine Disorders; Nifedipine; Nimodipine | 1993 |
Calcium antagonists as an add-on therapy for drug-resistant epilepsy.
Topics: Anticonvulsants; Calcium Channel Blockers; Drug Resistance; Epilepsy; Flunarizine; Humans; Nifedipine; Nimodipine; Randomized Controlled Trials as Topic | 2001 |
Calcium antagonists for Duchenne muscular dystrophy.
Topics: Calcium Channel Blockers; Diltiazem; Flunarizine; Humans; Muscle Strength; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nifedipine; Randomized Controlled Trials as Topic; Verapamil | 2008 |
Calcium antagonists as an add-on therapy for drug-resistant epilepsy.
Topics: Anticonvulsants; Calcium Channel Blockers; Drug Resistance; Drug Therapy, Combination; Epilepsy; Flunarizine; Humans; Nifedipine; Nimodipine; Randomized Controlled Trials as Topic | 2013 |
4 trial(s) available for nifedipine and flunarizine
Article | Year |
---|---|
[Calcium channel blockers and prevention of migraine].
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Diltiazem; Flunarizine; Humans; Migraine Disorders; Nifedipine; Nimodipine; Verapamil | 1992 |
Treatment of Tourette's syndrome with calcium antagonists.
Topics: Adolescent; Adult; Calcium Channel Blockers; Female; Flunarizine; Humans; Male; Nifedipine; Tic Disorders; Tourette Syndrome | 1990 |
Comparative efficacy of calcium antagonist drugs in the prophylaxis of migraine.
Topics: Calcium Channel Blockers; Cinnarizine; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Flunarizine; Humans; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil | 1985 |
Comparison of the efficacy between flunarizine and nifedipine in the prophylaxis of migraine.
Topics: Adolescent; Adult; Double-Blind Method; Female; Flunarizine; Humans; Male; Middle Aged; Migraine Disorders; Nifedipine | 1993 |
99 other study(ies) available for nifedipine and flunarizine
Article | Year |
---|---|
Synthesis, calcium-channel-blocking activity, and antihypertensive activity of 4-(diarylmethyl)-1-[3-(aryloxy)propyl]piperidines and structurally related compounds.
Topics: Animals; Antihypertensive Agents; Aorta; Calcium; Calcium Channel Blockers; Hypertension; Male; Molecular Structure; Muscle Contraction; Piperidines; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship | 1991 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain | 2016 |
Long-term treatment with different calcium- and calmodulin-antagonists induces changes in rat brain alpha-adrenoceptors.
Topics: Administration, Oral; Animals; Calcium Channel Blockers; Calmodulin; Cerebral Cortex; Dioxanes; Flunarizine; Male; Nifedipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regression Analysis; Trifluoperazine; Verapamil | 1992 |
The calcium channel blocker LAS 30538, unlike nifedipine, verapamil, diltiazem or flunarizine, potently inhibits insulin secretion in-vivo in rats and dogs.
Topics: Administration, Oral; Animals; Blood Glucose; Calcium Channel Blockers; Diltiazem; Dogs; Female; Flunarizine; Glucose Tolerance Test; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nifedipine; Piperidines; Rats; Rats, Sprague-Dawley; Verapamil | 1992 |
Increased spontaneous cell detachment of F10 cells induced in vitro by some calcium-channel blockers.
Topics: Animals; Calcium Channel Blockers; Cell Adhesion; Culture Media; Flunarizine; Growth Inhibitors; Melanoma, Experimental; Nifedipine; Tumor Cells, Cultured; Tumor Stem Cell Assay; Verapamil | 1992 |
Antitussive effects of Ca2+ channel antagonists.
Topics: Animals; Antitussive Agents; Calcium Channel Blockers; Capsaicin; Codeine; Cough; Dextromethorphan; Drug Interactions; Drug Synergism; Flunarizine; Guinea Pigs; Male; Morphine; Nifedipine; Verapamil | 1992 |
Effects of calcium antagonists on the cocaine- and methamphetamine-induced conditioned place preference.
Topics: Animals; Calcium Channel Blockers; Cocaine; Conditioning, Psychological; Diltiazem; Dose-Response Relationship, Drug; Flunarizine; Male; Methamphetamine; Nifedipine; Rats; Rats, Inbred Strains | 1992 |
Changes in benzodiazepine receptors of rat brain after long-term treatment with the Ca(2+)-antagonists nifedipine, verapamil, flunarizine and with the calmodulin antagonist trifluoperazine.
Topics: Animals; Brain Chemistry; Calcium Channel Blockers; Calmodulin; Cerebral Cortex; Flunarizine; Flunitrazepam; Hippocampus; Kinetics; Male; Nifedipine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Trifluoperazine; Verapamil | 1991 |
Flunarizine selectively blocks transient calcium channel currents in N1E-115 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Electrophysiology; Flunarizine; Mice; Microelectrodes; Neuroblastoma; Nifedipine; Tumor Cells, Cultured | 1990 |
Nimodipine enhances spontaneous activity of hippocampal pyramidal neurons in aging rabbits at a dose that facilitates associative learning.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Aging; Analysis of Variance; Animals; Catheterization; Conditioning, Eyelid; Dose-Response Relationship, Drug; Female; Flunarizine; Hippocampus; Neurons; Nifedipine; Nimodipine; Rabbits; Software | 1990 |
Effects of calcium channel blockers on renal function in mice.
Topics: Animals; Calcium Channel Blockers; Chromium Radioisotopes; Cinnarizine; Edetic Acid; Female; Flunarizine; Glomerular Filtration Rate; Kidney; Mice; Mice, Inbred C3H; Nifedipine; Verapamil | 1992 |
Tetrandrine: a novel calcium channel antagonist inhibits type I calcium channels in neuroblastoma cells.
Topics: Alkaloids; Animals; Barium; Benzylisoquinolines; Calcium Channel Blockers; Flunarizine; Kinetics; Membrane Potentials; Mice; Neuroblastoma; Nifedipine; Tumor Cells, Cultured | 1991 |
The long-term treatment with the Ca(2+)-antagonists nifedipine, verapamil, flunarizine and with the calmodulin antagonist trifluoperazine decreases the activity of 5-HT1 receptors in rat cerebral cortex and hippocampus.
Topics: Animals; Calcium Channel Blockers; Calmodulin; Cerebral Cortex; Flunarizine; Hippocampus; In Vitro Techniques; Kinetics; Male; Nifedipine; Rats; Rats, Inbred Strains; Serotonin Antagonists; Trifluoperazine; Verapamil | 1991 |
Caffeine-induced contractions in rabbit isolated renal artery are differentially inhibited by calcium antagonists.
Topics: Animals; Bepridil; Caffeine; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Fendiline; Flunarizine; Kinetics; Lidoflazine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Renal Artery; Verapamil | 1991 |
Effects of verapamil, nifedipine and flunarizine on haemodynamics and regional blood flows in pentobarbitone-anaesthetized rats.
Topics: Anesthesia; Animals; Calcium Channel Blockers; Cardiac Output; Electrocardiography; Flunarizine; Heart Rate; Hemodynamics; Male; Nifedipine; Pentobarbital; Rats; Rats, Inbred Strains; Regional Blood Flow; Renal Circulation; Verapamil | 1990 |
Increased toxicity of anthracycline antibiotics induced by calcium entry blockers in cultured cardiomyocytes.
Topics: Animals; Antibiotics, Antineoplastic; Calcium Channel Blockers; Cells, Cultured; Daunorubicin; Doxorubicin; Drug Resistance; Drug Synergism; Flunarizine; Heart; Nifedipine; Rats | 1991 |
45Ca2+ movements induced by Ca2+ chloride in isolated rat aorta under K(+)-free conditions.
Topics: Amiloride; Animals; Aorta, Thoracic; Benzothiazoles; Calcium; Calcium Chloride; Calcium Radioisotopes; Flunarizine; In Vitro Techniques; Indomethacin; Lanthanum; Lidocaine; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Piperidines; Potassium; Rats; Thiazoles; Vasoconstriction | 1991 |
Influence of long-term treatment with the Ca2(+)-antagonists nifedipine, verapamil, flunarizine and with the calmodulin antagonist trifluoperazine on beta-adrenoceptors in rat cerebral cortex.
Topics: Animals; Calcium Channel Blockers; Calmodulin; Cerebral Cortex; Dihydroalprenolol; Flunarizine; Male; Membrane Fluidity; Membranes; Nifedipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Synaptosomes; Trifluoperazine; Verapamil | 1990 |
Attenuation of the low-density-lipoprotein-activated phosphoinositide signalling system by calcium blockers in human lymphocytes.
Topics: Calcium Channel Blockers; Cells, Cultured; Cholesterol, LDL; Diglycerides; Diltiazem; Dose-Response Relationship, Drug; Flunarizine; Humans; Lymphocytes; Molsidomine; Nifedipine; Phosphatidylinositols; Protein Kinase C; Verapamil | 1990 |
Effects of the Ca2(+)-antagonists nifedipine, verapamil, flunarizine and of the calmodulin antagonist trifluoperazine on muscarinic cholinergic receptors in rat cerebral cortex.
Topics: Animals; Calcium Channel Blockers; Calmodulin; Cerebral Cortex; Flunarizine; Kinetics; Male; Nifedipine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Trifluoperazine; Verapamil | 1990 |
Effects of calcium antagonists on biogenic amines in discrete brain areas.
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Electrochemistry; Flunarizine; Male; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1990 |
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cinnarizine; Diltiazem; Flunarizine; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Phenytoin; Pheochromocytoma; Potassium; Rats; Sodium; Verapamil | 1985 |
Muscarinic cholinergic enhancement of inositide turnover in cerebral nerve endings is not mediated by calcium uptake.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcimycin; Calcium; Carbachol; Cinnarizine; Flunarizine; Male; Nerve Endings; Nicotinic Acids; Nifedipine; Nimodipine; Phosphatidic Acids; Phosphatidylinositols; Rats; Rats, Inbred Strains; Verapamil; Veratridine | 1986 |
[Mechanism of action of calcium antagonists in the treatment of vascular diseases].
Topics: Arterial Occlusive Diseases; Calcium; Calcium Channel Blockers; Cerebrovascular Circulation; Flunarizine; Humans; Ion Channels; Migraine Disorders; Muscle, Smooth, Vascular; Nifedipine | 1986 |
Ethanol-induced component of 45Ca2+ uptake in PC12 cells is sensitive to Ca2+ channel modulating drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cell Line; Diltiazem; Drug Interactions; Ethanol; Flunarizine; Ion Channels; Nifedipine; Verapamil | 1987 |
Histamine stimulated synaptosomal Ca2+ uptake through activation of calcium channels.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Bucladesine; Calcium; Cinnarizine; Cyclic AMP; Diltiazem; Flunarizine; Histamine; Ion Channels; Nifedipine; Rats; Synaptosomes; Verapamil | 1988 |
Distinction of two components of passive Ca2+ transport into human erythrocytes by Ca2+ entry blockers.
Topics: Aminoquinolines; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability; Cobalt; Copper; Diltiazem; Erythrocyte Membrane; Flunarizine; Humans; Nifedipine; Vanadates; Verapamil | 1989 |
Modification of tumour response by calcium antagonists in the SCVII/St tumour implanted at two different sites.
Topics: Animals; Back; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Flunarizine; Hindlimb; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nifedipine; Radiation Tolerance; Rubidium; Verapamil | 1989 |
Role of endothelium in the contractile response of rat aorta to alpha-adrenoceptor agonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Calcium; Cinnarizine; Endothelium; Flunarizine; Guanfacine; Guanidines; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phenylacetates; Rats; Rats, Inbred Strains | 1985 |
Calcium antagonists as radiation modifiers: site specificity in relation to tumor response.
Topics: Animals; Calcium Channel Blockers; Combined Modality Therapy; Female; Flunarizine; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nifedipine; Radiation-Sensitizing Agents; Verapamil | 1989 |
Effects of calcium entry blockers on human platelet metabolism measured by microcalorimetry.
Topics: Blood Platelets; Calcium Channel Blockers; Calorimetry; Cerebral Arteries; Diltiazem; Flunarizine; Humans; Muscle Relaxation; Nifedipine; Verapamil | 1989 |
Different sensitivities for four calcium entry blockers of serotonin-, but not K+-induced contractions of isolated jugular vein and aorta of the rat.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Diltiazem; Flunarizine; Gallopamil; In Vitro Techniques; Jugular Veins; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Serotonin | 1989 |
Selective modulation by membrane potential of the interaction of some calcium entry blockers with calcium channels in rat mesenteric artery.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Flunarizine; In Vitro Techniques; Isradipine; Membrane Potentials; Membranes; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Oxadiazoles; Rats; Rats, Inbred Strains | 1988 |
Calcium channel antagonists. Omega-conotoxin defines a new high affinity site.
Topics: Animals; Binding, Competitive; Brain; Calcium Channel Blockers; Chick Embryo; Cinnarizine; Diltiazem; Flunarizine; Muscles; Nifedipine; Nitrendipine; Prenylamine; Rana pipiens; Synaptosomes; Time Factors; Verapamil | 1986 |
Augmentation by calcium channel antagonists of general anaesthetic potency in mice.
Topics: Anesthesia, General; Animals; Argon; Calcium Channel Blockers; Cinnarizine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Flunarizine; Male; Mice; Nifedipine; Nitrendipine; Pentobarbital; Time Factors; Verapamil | 1986 |
[Facilitation of the onset of tetanic responses induced by 4-methylesculetol in amphibian isolated neuromuscular preparations].
Topics: Acetylcholine; Animals; Calcium; Cinnarizine; Drug Interactions; Flunarizine; In Vitro Techniques; Muscle Contraction; Neuromuscular Junction; Nifedipine; Rana esculenta; Scopoletin; Synaptic Transmission; Umbelliferones | 1985 |
Ineffectiveness of organic calcium channel blockers in antagonizing long-term potentiation.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Cinnarizine; Diazepam; Flunarizine; Guinea Pigs; Hippocampus; Neurons; Nifedipine; Nitrendipine; Reaction Time; Synaptic Transmission; Verapamil | 1986 |
Mechanisms of flunarizine-induced vasodilation in the rabbit mesenteric artery.
Topics: Animals; Biomechanical Phenomena; Caffeine; Calcium; Flunarizine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phosphatidic Acids; Phosphatidylinositols; Potassium; Rabbits; Vasodilation | 1987 |
Studies of [3H]nitrendipine binding and KCl-induced calcium uptake in rat cortical synaptosomes.
Topics: Animals; Calcium; Calcium Channel Blockers; Cerebral Cortex; Cinnarizine; Flunarizine; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes | 1985 |
The classification of calcium antagonists by the WHO expert committee: relevance in neurology.
Topics: Brain Diseases; Calcium Channel Blockers; Diltiazem; Flunarizine; Humans; Nifedipine; Verapamil | 1988 |
Different effects of R 56865 and calcium entry blockers on K+- and noradrenaline-induced contractions and 45Ca uptake in rat aorta.
Topics: Animals; Aorta; Benzothiazoles; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Flunarizine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Piperidines; Potassium; Rats; Rats, Inbred Strains; Thiazoles; Verapamil | 1988 |
Aggravation of Parkinson's disease by cinnarizine.
Topics: Animals; Caudate Nucleus; Cinnarizine; Dopamine; Flunarizine; Male; Nifedipine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1988 |
Variable results of calcium blockade in post-ischaemic renal failure.
Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Flunarizine; Ischemia; Kidney; Male; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1988 |
The effects of calcium channel blocking drugs on halothane initiation of malignant hyperthermia in MHS swine and on the established syndrome.
Topics: Anesthesia, General; Animals; Calcium Channel Blockers; Diltiazem; Flunarizine; Halothane; Malignant Hyperthermia; Nifedipine; Nisoldipine; Swine; Verapamil | 1988 |
Verapamil as an apparent competitive antagonist of the serotonin receptor of rabbit isolated aorta.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Cinnarizine; Diltiazem; Flunarizine; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Receptors, Serotonin; Verapamil | 1986 |
Nifedipine and flunarizine block amphetamine-induced behavioral stimulation in mice.
Topics: Animals; Calcium Channel Blockers; Cinnarizine; Dextroamphetamine; Dose-Response Relationship, Drug; Flunarizine; Mice; Motor Activity; Nifedipine | 1986 |
Polymorphonuclear leucocytes as a model of Ca++ and Mg++-dependent cellular activation. Effect of calcium entry blockers.
Topics: Calcimycin; Calcium; Calcium Channel Blockers; Cell Aggregation; Cinnarizine; Flunarizine; Glucuronidase; Humans; Kinetics; Magnesium; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nifedipine | 1985 |
Isolated rat cardiac myocytes as an experimental model to study calcium overload: the effect of calcium-entry blockers.
Topics: Animals; Calcium; Calcium Channel Blockers; Cinnarizine; Diltiazem; Flunarizine; Heart; Lidoflazine; Male; Myocardial Contraction; Myocardium; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Time Factors; Verapamil; Veratrine | 1986 |
Pupillary and vascular effects of calcium antagonists in migraine.
Topics: Blood Pressure; Calcium Channel Blockers; Cinnarizine; Flunarizine; Humans; Migraine Disorders; Nifedipine; Pupil; Vasoconstriction; Verapamil | 1985 |
Evaluation of calcium entry blockers in several models of immediate hypersensitivity.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acids; Bronchial Spasm; Calcium Channel Blockers; Cinnarizine; Diltiazem; Flunarizine; Guinea Pigs; Histamine Release; Hydroxyeicosatetraenoic Acids; Hypersensitivity, Immediate; Lipoxygenase; Male; Mast Cells; Nifedipine; Rats; Verapamil | 1984 |
A calcium antagonist drug binding site in skeletal muscle sarcoplasmic reticulum: evidence for a calcium channel.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Cinnarizine; Egtazic Acid; Flunarizine; Gallic Acid; Ion Channels; Muscle Contraction; Neuromuscular Junction; Nifedipine; Nitrendipine; Pyridines; Rabbits; Sarcoplasmic Reticulum; Verapamil | 1983 |
Effect of calcium-entry blockers and divalent cations on noradrenaline-induced contractions of the rat anococcygeus muscle.
Topics: Animals; Calcium Channel Blockers; Cations; Cinnarizine; Cobalt; Diltiazem; Flunarizine; In Vitro Techniques; Male; Manganese; Muscle Contraction; Muscles; Nifedipine; Norepinephrine; Potassium; Rats; Sacrococcygeal Region | 1984 |
Pharmacological protection against hypoxia-induced effects on medium-term memory in a two-way avoidance paradigm.
Topics: Animals; Avoidance Learning; Calcium Channel Blockers; Cerebral Cortex; Cinnarizine; Dose-Response Relationship, Drug; Flunarizine; Guinea Pigs; Hypoxia, Brain; Male; Memory; Mental Recall; Nicotinic Acids; Nifedipine; Nimodipine; Retention, Psychology; Vasodilation; Verapamil | 1984 |
High affinity binding sites for [3H]-nitrendipine in rabbit uterine smooth muscle.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Cell Membrane; Cinnarizine; Depression, Chemical; Dose-Response Relationship, Drug; Female; Flunarizine; Muscle, Smooth; Nifedipine; Nitrendipine; Rabbits; Uterus; Verapamil | 1984 |
Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cinnarizine; Cobalt; Dose-Response Relationship, Drug; Drug Synergism; Flunarizine; Guinea Pigs; Ileum; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyridines; Structure-Activity Relationship; Verapamil | 1983 |
Calcium entry blockers and vascular smooth muscle heterogeneity.
Topics: Animals; Calcium; Calcium Channel Blockers; Cinnarizine; Flunarizine; Gallopamil; Lidoflazine; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Verapamil | 1981 |
Clinical use of calcium entry blockers.
Topics: Angina Pectoris; Calcium Channel Blockers; Cinnarizine; Coronary Circulation; Coronary Vasospasm; Diltiazem; Flunarizine; Heart Rate; Humans; Lidoflazine; Nifedipine; Perhexiline; Verapamil | 1981 |
Modulation of acetylcholine release in rat hippocampus by amino alcohols and Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium; Cerebral Cortex; Choline; Corpus Striatum; Diltiazem; Dose-Response Relationship, Drug; Ethanolamine; Ethanolamines; Flunarizine; Hippocampus; In Vitro Techniques; Male; Nifedipine; Osmolar Concentration; Potassium Chloride; Propanolamines; Pyrrolidines; Rats; Rats, Inbred F344; Verapamil | 1993 |
Calcium channel blockers improve hypoxia/hypoglycemia-induced impairment of rat hippocampal 2-deoxyglucose uptake in vitro after ethanol withdrawal.
Topics: Animals; Calcium Channel Blockers; Deoxyglucose; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; Flunarizine; Glutamic Acid; Hippocampus; Hypoglycemia; Hypoxia; Male; Nifedipine; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 1995 |
Effects of L-type calcium channel antagonists on the serotonin-depleting actions of MDMA in rats.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Calcium Channel Blockers; Cerebral Cortex; Flunarizine; Haloperidol; Hippocampus; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nifedipine; Rats; Rats, Sprague-Dawley; Seizures; Serotonin; Stereotyped Behavior; Verapamil | 1993 |
Inhibition of endogenous acetylcholine release by blockade of voltage-dependent calcium channels in enteric neurons of the guinea-pig colon.
Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Colon; Electric Stimulation; Electrophysiology; Flunarizine; Guinea Pigs; In Vitro Techniques; Male; Neurons; Nifedipine; omega-Conotoxin GVIA; Peptides, Cyclic | 1993 |
Metal ions affect neuronal membrane fluidity of rat cerebral cortex.
Topics: Animals; Cations; Cerebral Cortex; Cyclic N-Oxides; Edetic Acid; Egtazic Acid; Electron Spin Resonance Spectroscopy; Flunarizine; Kinetics; Male; Membrane Fluidity; Metals; Neurons; Nicardipine; Nifedipine; Nimodipine; Rats; Rats, Sprague-Dawley; Spin Labels; Synaptosomes | 1994 |
Effect of a Ca2+ entry blocker, nilvadipine, on hearing disturbances and equilibrium dysfunction caused by microcirculatory disorders of the rat inner ear.
Topics: Acoustic Stimulation; Action Potentials; Analysis of Variance; Animals; Calcium Channel Blockers; Cochlea; Ear, Inner; Flunarizine; Hearing Disorders; Laser-Doppler Flowmetry; Nifedipine; Rats; Rats, Wistar; Regional Blood Flow; Sensation Disorders; Ultraviolet Rays | 1993 |
Effects of Ca2+ channel blockers on physical dependence on diazepam in mice.
Topics: Animals; Brain; Calcium Channel Blockers; Carbolines; Diazepam; Diltiazem; Drug Interactions; Flunarizine; Male; Mice; Mice, Inbred ICR; Nifedipine; Receptors, GABA-A; Seizures; Substance-Related Disorders | 1993 |
Radioprotective effects of calcium antagonists used alone or with other types of radioprotectors.
Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Diltiazem; Dimethyl Sulfoxide; Drug Combinations; Female; Flunarizine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Radiation-Protective Agents; Verapamil; Zinc | 1993 |
Protective effect of flunarizine and nifedipine alone and in combination with anticonvulsant drugs against PTZ-induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Female; Flunarizine; Male; Mice; Nifedipine; Pentylenetetrazole; Phenytoin; Seizures | 1993 |
Effects of calcium antagonists nifedipine and flunarizine on phencyclidine-induced changes in the regional dopaminergic metabolism of the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Mapping; Calcium Channel Blockers; Dopamine; Flunarizine; Hallucinogens; Homovanillic Acid; Male; Nifedipine; Phencyclidine; Rats; Rats, Inbred Strains | 1996 |
[Direct evidence of a protective effect of calcium antagonists on the inner ear. Inhibition of a toxic increase in the calcium level in hair cells of the guinea pig].
Topics: Animals; Calcium; Calcium Channel Blockers; Culture Techniques; Dose-Response Relationship, Drug; Female; Flunarizine; Guinea Pigs; Hair Cells, Auditory; Hair Cells, Auditory, Outer; Male; Membrane Potentials; Nifedipine; Potassium; Second Messenger Systems; Signal Transduction; Verapamil | 1995 |
Effect of calcium antagonists on regional cerebral blood flow in transplanted rat brain tumors.
Topics: Analysis of Variance; Animals; Brain; Brain Neoplasms; Calcium Channel Blockers; Cerebrovascular Circulation; Diltiazem; Flunarizine; Glioma; Male; Neoplasm Transplantation; Nifedipine; Nimodipine; Rats; Rats, Wistar; Verapamil | 1996 |
Ca2+ channel blockade and the antielectroshock activity of NMDA receptor antagonists, CGP 40116 and CGP 43487, in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Excitatory Amino Acid Antagonists; Flunarizine; Male; Mice; Nicardipine; Nifedipine; Receptors, N-Methyl-D-Aspartate | 1996 |
Anticonvulsant and adverse effects of MK-801, LY 235959, and GYKI 52466 in combination with Ca2+ channel inhibitors in mice.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Avoidance Learning; Benzodiazepines; Calcium Channel Blockers; Dizocilpine Maleate; Drug Interactions; Electroshock; Excitatory Amino Acid Antagonists; Flunarizine; Isoquinolines; Male; Mice; Motor Activity; Nicardipine; Nifedipine; Seizures | 1997 |
Effect of 4-aminopyridine and 3,4-diaminopyridine on guinea-pig isolated ileum.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Animals; Atropine; Calcium Channel Blockers; Diazoxide; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Female; Flunarizine; Guinea Pigs; Ileum; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Parasympathetic Nervous System; Parasympatholytics; Potassium Channels; Vasodilator Agents; Verapamil | 1997 |
Differentiation of the inhibitory effects of calcium antagonists on abnormal behaviors induced by methamphetamine or phencyclidine.
Topics: Amygdala; Animals; Behavior, Animal; Calcium Channel Blockers; Caudate Nucleus; Central Nervous System Stimulants; Dopamine Uptake Inhibitors; Flunarizine; Injections, Intraperitoneal; Male; Methamphetamine; Microinjections; Motor Activity; Nicardipine; Nifedipine; Phencyclidine; Putamen; Rats; Rats, Wistar | 1998 |
Effect of nilvadipine on the voltage-dependent Ca2+ channels in rat hippocampal CA1 pyramidal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Flunarizine; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar | 1998 |
Effect of calcium antagonists on the response to noradrenaline in the whole and bisected rat vas deferens.
Topics: Animals; Calcium Channel Blockers; Cromakalim; Diltiazem; Flunarizine; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Organ Culture Techniques; Papaverine; Rats; Rats, Wistar; Vas Deferens | 1998 |
High sensitivity of immature GABAergic neurons to blockers of voltage-gated calcium channels.
Topics: Acetylcholine; Animals; Calcium Channel Blockers; Cell Death; Cells, Cultured; Cellular Senescence; Cycloheximide; Flunarizine; gamma-Aminobutyric Acid; Ion Channel Gating; Membrane Potentials; Neurons; Nifedipine; Rats; Rats, Sprague-Dawley | 1999 |
Effect of voltage-dependent calcium channel blockers on ethanol-induced beta-endorphin release from hypothalamic neurons in primary cultures.
Topics: Animals; beta-Endorphin; Calcium Channel Blockers; Calcium Channels; Calcium Channels, N-Type; Cell Survival; Cells, Cultured; Ethanol; Flunarizine; Hypothalamus; Neurons; Nifedipine; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1999 |
Different effects of L-type and T-type calcium channel blockers on the hypnotic potency of triazolam and zolpidem in rats.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, T-Type; Drug Interactions; Flunarizine; Hypnotics and Sedatives; Male; Nifedipine; Pyridines; Rats; Rats, Wistar; Sleep, REM; Triazolam; Zolpidem | 1999 |
PMCA1 mRNA expression in rat aortic myocytes: a real-time RT-PCR study.
Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cation Transport Proteins; Cattle; Cells, Cultured; Flunarizine; Gene Expression Regulation, Enzymologic; Imidazoles; Male; Muscle, Smooth; Nifedipine; Plasma Membrane Calcium-Transporting ATPases; Protein Isoforms; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Up-Regulation | 2000 |
Subtypes of low voltage-activated Ca2+ channels in laterodorsal thalamic neurons: possible localization and physiological roles.
Topics: Amiloride; Animals; Calcium Channel Blockers; Calcium Channels; Diuretics; Flunarizine; Ion Channel Gating; Kinetics; Lanthanum; Lateral Thalamic Nuclei; Membrane Potentials; Nickel; Nifedipine; Patch-Clamp Techniques; Rats | 2001 |
Pharmacological involvement of the calcium channel blocker flunarizine in dopamine transmission at the striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Calcium Channel Blockers; Calcium Channels, L-Type; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Flunarizine; Haloperidol; Male; Microinjections; Neostriatum; Nifedipine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Synapses; Synaptic Transmission | 2001 |
Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Benzothiadiazines; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flunarizine; Gene Expression Regulation, Developmental; Ion Channel Gating; Lanthanum; Macromolecular Substances; Mice; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nifedipine; omega-Conotoxins; Polyamines; Protein Subunits; Receptors, AMPA; Sodium; Sodium Channels; Sodium-Calcium Exchanger; Spermine; Tetrodotoxin | 2001 |
Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Calcium; Calcium Channel Blockers; Choline O-Acetyltransferase; Electroretinography; Excitatory Amino Acid Agonists; Flunarizine; Intraocular Pressure; N-Methylaspartate; Neuroprotective Agents; Nifedipine; Parvalbumins; Rabbits; Rats; Rats, Wistar; Reperfusion Injury; Retina; RNA, Messenger; Sodium; Thy-1 Antigens; Vasodilator Agents | 2002 |
Influence of agents affecting voltage-dependent calcium channels and dantrolene on the anticonvulsant action of the AMPA/kainate receptor antagonist LY 300164 in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Benzodiazepines; Calcium Channel Blockers; Calcium Channels; Dantrolene; Dose-Response Relationship, Drug; Drug Interactions; Flunarizine; Glafenine; Male; Mice; Nifedipine; Psychomotor Performance; Receptors, AMPA | 2002 |
Ionic involvement and kinase activity on the mechanism of nongenomic action of thyroid hormones on 45Ca2+ uptake in cerebral cortex from young rats.
Topics: Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flunarizine; In Vitro Techniques; Ion Channels; Nifedipine; Protein Kinases; Rats; Rats, Wistar; Thyroid Hormones; Time Factors | 2007 |
Evidence for postsynaptic modulation of muscle contraction by a Drosophila neuropeptide.
Topics: Amiloride; Amino Acid Sequence; Animals; Calcium Channels, L-Type; Calcium Channels, T-Type; Dose-Response Relationship, Drug; Drosophila; Flunarizine; FMRFamide; Glutamic Acid; Larva; Molecular Sequence Data; Muscle Contraction; Nicardipine; Nifedipine; Receptors, Glutamate; Synaptic Transmission | 2008 |
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Glioma; Glutamic Acid; Lidocaine; Luminescence; Nickel; Nifedipine; Rats; Veratridine | 2008 |
Vasodilator effects of flunarizine on retinal blood vessels in anesthetized rats.
Topics: Anesthesia; Animals; Blood Pressure; Dose-Response Relationship, Drug; Flunarizine; Male; Nifedipine; Rats; Rats, Wistar; Retinal Artery; Retinal Vein; Vasodilator Agents | 2009 |
Comparative effects of T-type and L-type Ca(2+)-antagonists against noradrenaline-induced contractions of human vas deferens.
Topics: Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Flunarizine; Humans; Male; Mibefradil; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Pyrroles; Vas Deferens | 2010 |
Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracellular calcium levels by selected L-type calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Child; Drug Evaluation, Preclinical; Flunarizine; Humans; Intracellular Space; Membrane Glycoproteins; Molecular Chaperones; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Nicardipine; Nifedipine; Nimodipine; Potassium Chloride; RNA Interference; RNA, Small Interfering | 2011 |
HOCl causes necrotic cell death in human monocyte derived macrophages through calcium dependent calpain activation.
Topics: Calcimycin; Calcium; Calcium Channel Blockers; Calcium Ionophores; Calpain; Caspase 3; Cyclosporine; Dantrolene; Enzyme Inhibitors; Flunarizine; Humans; Hypochlorous Acid; Lysosomes; Macrophages; Membrane Potential, Mitochondrial; Muscle Relaxants, Central; Necrosis; Nifedipine; Verapamil | 2012 |
T-type Ca²⁺ signalling downregulates MEK1/2 phosphorylation and cross-talk with the RAAS transcriptional response in cardiac myocytes.
Topics: Animals; Calcium Signaling; Flunarizine; Fluoxetine; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mibefradil; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Nifedipine; Phosphorylation; Rats; Rats, Wistar; Receptors, Glucocorticoid; Renin-Angiotensin System; Spironolactone | 2012 |
Novel pharmacological modulation of dystonic phenotypes caused by a gain-of-function mutation in the Na+ leak-current channel.
Topics: Animals; Boron Compounds; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dystonia; Ethoxzolamide; Flunarizine; Gain of Function Mutation; Gene Knockout Techniques; Ion Channels; Motor Disorders; Nifedipine; Nimodipine; Phenotype; Sodium Channels | 2020 |