nifedipine and flunarizine

nifedipine has been researched along with flunarizine in 113 studies

Research

Studies (113)

TimeframeStudies, this research(%)All Research%
pre-199042 (37.17)18.7374
1990's45 (39.82)18.2507
2000's13 (11.50)29.6817
2010's12 (10.62)24.3611
2020's1 (0.88)2.80

Authors

AuthorsStudies
Barrett, RJ; Johnson, CP; Proakis, AG; Shanklin, JR1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Janis, RA; Triggle, DJ1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Brouillette, WJ; Brown, GB; Zha, C1
Bennis, K; Ducki, S; Lesage, F; Vivier, D1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN1
Dong, G; Liu, N; Sheng, C; Tu, J; Wang, Y1
Dantchev, N; Popov, P; Staneva-Stoytcheva, D1
Montastruc, JL; Senard, JM1
Berga, P; Furman, BL; Gristwood, RW; Jauregui, J; Llenas, J1
D'Ancona, S; Mazzo, M; Pea, F1
Kamei, J; Kasuya, Y1
Masukawa, Y; Misawa, M; Shiozaki, Y; Suzuki, T1
Danchev, N; Popov, P; Staneva-Stoytcheva, D1
Karpinski, E; Pang, PK; Wang, R; Wu, LY1
Deyo, RA; Disterhoft, JF; Thompson, LT1
Bleehen, NM; Honess, DJ1
Karpinski, E; Liu, QY; Pang, PK; Rao, MR1
Ivanova, E; Popova, J; Staneva-Stoytcheva, D; Tosheva, T1
Fabrègues, E; John, GW; Kamal, M; Massingham, R1
Pang, CC; Waite, RP; Walker, MJ1
Krishna, G; Kutty, RK; Santostasi, G1
Nebel, U; Wermelskirchen, D; Wilffert, B; Wirth, A1
Alov, P; Mutafova-Yambolieva, V; Popova, J; Staneva-Stoytcheva, D1
Locher, R; Sachinidis, A; Steiner, A; Vetter, W1
Casas Parera, I; Fernandez Pardal, M; Gatto, M; Lekhuniec, E; Mangone, C; Micheli, F; Pikielny, R1
Mutafova, V; Popova, J; Staneva-Stoytcheva, D1
Gaggi, R; Gianni, AM1
Carpenter, CL; Greenberg, DA; Messing, RO2
Greenberg, DA1
Traber, J; Van Rooijen, LA1
Mayerhofer, S1
Blanco, I; Brandner, R; Rodriguez, J; Rodriguez, R; Sabrià, J; Toledo, A1
Duhm, J; Engelmann, B1
Hirst, DG; Wood, PJ2
Al Osachie, I; Egleme, C; Godfraind, T1
Edvinsson, L; Ikomi-Kumm, J; Monti, M1
Gouw, MA; van Zwieten, PA; Wilffert, B1
Godfraind, T; Morel, N1
Cruz, LJ; Olivera, BM1
Dolin, SJ; Little, HJ1
Aragno, R; Bettini, V; De Bartolomeis, L; Fabro, P; Munari, L; Ton, P1
Schwartzkroin, PA; Taube, JS1
Fujiwara, T; Ishimatsu, T; Itoh, T; Kanmura, Y; Satoh, S1
Baky, S; Nademanee, K; Singh, BN1
Chiang, DH; Wei, JW1
Agnoli, A1
Koch, P; Nebel, U; Peters, T; Wermelskirchen, D; Wilffert, B; Wilhelm, D1
Fernandez Pardal, J; Fernandez Pardal, M; Micheli, F1
Fitzpatrick, JM; Leahy, AL; Wait, RB1
Harrison, GG; Morrell, DF; Wright, IG1
Auguet, M; Clostre, F; DeFeudis, FV; Delaflotte, S1
Grebb, JA1
Henry, PD1
Solomon, GD1
Capecchi, PL; Ceccatelli, L; Di Perri, T; Laghi Pasini, F; Orrico, A; Pasqui, AL1
Borgers, M; Donck, LV; Pauwels, PJ; Vandeplassche, G1
Boccuni, M; Cangi, F; Fanciullacci, M; Fusco, BM; Gatto, G; Marabini, S; Pietrini, U1
Bishop, CM; Capetola, RJ; Hedli, CC; Levinson, SL; Ritchie, DM; Sierchio, JN1
Beatty, DA; Colker, JE; Fairhurst, AS; Thayer, SA1
Oriowo, MA1
Clincke, GH; Wauquier, A1
Miller, WC; Moore, JB1
Bolger, GT; Gengo, P; Janis, RA; Klockowski, R; Luchowski, E; Siegel, H; Triggle, AM; Triggle, DJ1
Van Nueten, JM; Vanhoutte, PM1
Flaim, SF; Zelis, R1
Abbe, R; Appel, SH; Bostwick, JR1
Shibata, S; Shindou, T; Tominaga, K; Watanabe, S1
Calder, L; Clikeman, J; Finnegan, KT; Karler, R; Wei, S1
Castelletti, CM; De Ponti, F; Frigo, GM; Lecchini, S; Marcoli, M; Marino, F1
Wessely, P; Wöber-Bingöl, C1
Edamatsu, R; Hiramatsu, M; Mori, A; Mori, I; Ohba, S1
Asai, Y; Kohno, Y; Nakashima, M; Uematsu, T; Umemura, K1
Misawa, M; Mizoguchi, H; Suzuki, T; Yoshiike, M1
Lamsudin, R; Sadjimin, T1
Floersheim, GL1
Pleuvry, BJ; Rodger, C1
Etou, K; Hirano, M; Kuroki, T; Tashiro, N; Tatebayashi, Y1
Nilles, R1
Fukui, M; Ikezaki, K; Matsukado, K; Nomura, T1
Borowicz, K; Czuczwar, SJ; Gasior, M; Kleinrok, Z; Starownik, R2
Carvajal, A; Dueñas, A; Fernández de la Gándara, F; Maroto, M; Nieto, A; Velasco, A1
Hori, Y; Matsumiya, T; Takeda, H; Tsuji, M1
Akaike, N; Ishibashi, H; Murai, Y1
Barbieri, A; Bianchi, L; Boselli, C; Grana, E1
Honegger, P; Pardo, B1
Boyadjieva, NI; De, A; Sarkar, DK1
Higuchi, H; Hishikawa, Y; Shimizu, T; Takahashi, H; Yoshimoto, M1
Holman, NA; Mamic, TM; Monteith, GR; Roberts-Thomson, SJ1
Kostyuk, PG; Shuba, YM; Zhuravleva, SO1
Armando, I; Belforte, JE; Buño, W; Magariños-Azcone, C; Pazo, JH1
Jensen, JB; Lund, TM; Pickering, DS; Schousboe, A; Timmermann, DB1
Baillie, N; Chaisewikul, R; Marson, AG1
Chidlow, G; Cupido, A; Melena, J; Osborne, NN; Wood, JP1
Borowicz, KK; Czuczwar, SJ; Kleinrok, Z; Porebiak, J; Swiader, M1
Barreto, KP; Pessoa-Pureur, R; Royer, C; Silva, FR; Zamoner, A1
Clark, J; Cull, A; Klose, MK; Mercier, AJ; Milakovic, M1
Kitano, H; Shinohara, H; Zakir Hossain, SM1
Phillips, MF; Quinlivan, R1
Ishii, K; Mori, A; Nakahara, T; Noguchi, M; Sakamoto, K1
Amobi, N; Guillebaud, J; Smith, CH1
An Haack, K; Bennett, MJ; Li, H; Narayan, SB; Tan, L; Warnock, A1
Gieseg, SP; Whiteman, M; Yang, YT1
Capuano, V; Ferron, L; Renaud, JF; Ruchon, Y; Sankhe, S1
Hasan, M; Marson, AG; Pulman, J1
Aamodt, EJ; Dwyer, DS; Kasap, M; Sagrera, CE1

Reviews

12 review(s) available for nifedipine and flunarizine

ArticleYear
New developments in Ca2+ channel antagonists.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:6

    Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Electrophysiology; Heart; Humans; Ion Channels; Muscle Relaxation; Muscle, Smooth; Potassium; Sodium; Structure-Activity Relationship; Substrate Specificity

1983
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship

2016
Emerging New Targets for the Treatment of Resistant Fungal Infections.
    Journal of medicinal chemistry, 2018, 07-12, Volume: 61, Issue:13

    Topics: Antifungal Agents; Drug Resistance, Fungal; Humans; Molecular Targeted Therapy; Mycoses

2018
[Calcium channel blockers and prevention of migraine].
    Pathologie-biologie, 1992, Volume: 40, Issue:4

    Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Diltiazem; Flunarizine; Humans; Migraine Disorders; Nifedipine; Nimodipine; Verapamil

1992
Calcium channel antagonists and the treatment of migraine.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:4

    Topics: Calcium; Calcium Channel Blockers; Cinnarizine; Diltiazem; Flunarizine; Humans; Ion Channels; Kinetics; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil

1986
Second-generation calcium antagonists: search for greater selectivity and versatility.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Bepridil; Calcium Channel Blockers; Cinnarizine; Electrophysiology; Flunarizine; Heart; Humans; Lidoflazine; Muscle, Smooth, Vascular; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyrrolidines; Structure-Activity Relationship

1985
Atherosclerosis, calcium, and calcium antagonists.
    Circulation, 1985, Volume: 72, Issue:3

    Topics: Animals; Aorta; Arteries; Arteriosclerosis; Calcinosis; Calcium; Calcium Channel Blockers; Cell Survival; Cholesterol, Dietary; Cinnarizine; Diltiazem; Flunarizine; Humans; Membrane Lipids; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Propranolol; Rabbits; Verapamil

1985
Comparative efficacy of calcium antagonist drugs in the prophylaxis of migraine.
    Headache, 1985, Volume: 25, Issue:7

    Topics: Calcium Channel Blockers; Cinnarizine; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Flunarizine; Humans; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil

1985
[Calcium channel blockers in therapy of neurologic diseases].
    Wiener medizinische Wochenschrift (1946), 1993, Volume: 143, Issue:19-20

    Topics: Brain Ischemia; Calcium Channel Blockers; Cluster Headache; Flunarizine; Humans; Migraine Disorders; Nifedipine; Nimodipine

1993
Calcium antagonists as an add-on therapy for drug-resistant epilepsy.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Anticonvulsants; Calcium Channel Blockers; Drug Resistance; Epilepsy; Flunarizine; Humans; Nifedipine; Nimodipine; Randomized Controlled Trials as Topic

2001
Calcium antagonists for Duchenne muscular dystrophy.
    The Cochrane database of systematic reviews, 2008, Oct-08, Issue:4

    Topics: Calcium Channel Blockers; Diltiazem; Flunarizine; Humans; Muscle Strength; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nifedipine; Randomized Controlled Trials as Topic; Verapamil

2008
Calcium antagonists as an add-on therapy for drug-resistant epilepsy.
    The Cochrane database of systematic reviews, 2013, Mar-28, Issue:3

    Topics: Anticonvulsants; Calcium Channel Blockers; Drug Resistance; Drug Therapy, Combination; Epilepsy; Flunarizine; Humans; Nifedipine; Nimodipine; Randomized Controlled Trials as Topic

2013

Trials

4 trial(s) available for nifedipine and flunarizine

ArticleYear
[Calcium channel blockers and prevention of migraine].
    Pathologie-biologie, 1992, Volume: 40, Issue:4

    Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Diltiazem; Flunarizine; Humans; Migraine Disorders; Nifedipine; Nimodipine; Verapamil

1992
Treatment of Tourette's syndrome with calcium antagonists.
    Clinical neuropharmacology, 1990, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Calcium Channel Blockers; Female; Flunarizine; Humans; Male; Nifedipine; Tic Disorders; Tourette Syndrome

1990
Comparative efficacy of calcium antagonist drugs in the prophylaxis of migraine.
    Headache, 1985, Volume: 25, Issue:7

    Topics: Calcium Channel Blockers; Cinnarizine; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Flunarizine; Humans; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil

1985
Comparison of the efficacy between flunarizine and nifedipine in the prophylaxis of migraine.
    Headache, 1993, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Double-Blind Method; Female; Flunarizine; Humans; Male; Middle Aged; Migraine Disorders; Nifedipine

1993

Other Studies

99 other study(ies) available for nifedipine and flunarizine

ArticleYear
Synthesis, calcium-channel-blocking activity, and antihypertensive activity of 4-(diarylmethyl)-1-[3-(aryloxy)propyl]piperidines and structurally related compounds.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:10

    Topics: Animals; Antihypertensive Agents; Aorta; Calcium; Calcium Channel Blockers; Hypertension; Male; Molecular Structure; Muscle Contraction; Piperidines; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship

1991
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels

2014
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
    Chemical biology & drug design, 2016, Volume: 88, Issue:6

    Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain

2016
Long-term treatment with different calcium- and calmodulin-antagonists induces changes in rat brain alpha-adrenoceptors.
    General pharmacology, 1992, Volume: 23, Issue:1

    Topics: Administration, Oral; Animals; Calcium Channel Blockers; Calmodulin; Cerebral Cortex; Dioxanes; Flunarizine; Male; Nifedipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regression Analysis; Trifluoperazine; Verapamil

1992
The calcium channel blocker LAS 30538, unlike nifedipine, verapamil, diltiazem or flunarizine, potently inhibits insulin secretion in-vivo in rats and dogs.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:10

    Topics: Administration, Oral; Animals; Blood Glucose; Calcium Channel Blockers; Diltiazem; Dogs; Female; Flunarizine; Glucose Tolerance Test; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nifedipine; Piperidines; Rats; Rats, Sprague-Dawley; Verapamil

1992
Increased spontaneous cell detachment of F10 cells induced in vitro by some calcium-channel blockers.
    Journal of chemotherapy (Florence, Italy), 1992, Volume: 4, Issue:4

    Topics: Animals; Calcium Channel Blockers; Cell Adhesion; Culture Media; Flunarizine; Growth Inhibitors; Melanoma, Experimental; Nifedipine; Tumor Cells, Cultured; Tumor Stem Cell Assay; Verapamil

1992
Antitussive effects of Ca2+ channel antagonists.
    European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1

    Topics: Animals; Antitussive Agents; Calcium Channel Blockers; Capsaicin; Codeine; Cough; Dextromethorphan; Drug Interactions; Drug Synergism; Flunarizine; Guinea Pigs; Male; Morphine; Nifedipine; Verapamil

1992
Effects of calcium antagonists on the cocaine- and methamphetamine-induced conditioned place preference.
    Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence, 1992, Volume: 27, Issue:1

    Topics: Animals; Calcium Channel Blockers; Cocaine; Conditioning, Psychological; Diltiazem; Dose-Response Relationship, Drug; Flunarizine; Male; Methamphetamine; Nifedipine; Rats; Rats, Inbred Strains

1992
Changes in benzodiazepine receptors of rat brain after long-term treatment with the Ca(2+)-antagonists nifedipine, verapamil, flunarizine and with the calmodulin antagonist trifluoperazine.
    General pharmacology, 1991, Volume: 22, Issue:6

    Topics: Animals; Brain Chemistry; Calcium Channel Blockers; Calmodulin; Cerebral Cortex; Flunarizine; Flunitrazepam; Hippocampus; Kinetics; Male; Nifedipine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Trifluoperazine; Verapamil

1991
Flunarizine selectively blocks transient calcium channel currents in N1E-115 cells.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Electrophysiology; Flunarizine; Mice; Microelectrodes; Neuroblastoma; Nifedipine; Tumor Cells, Cultured

1990
Nimodipine enhances spontaneous activity of hippocampal pyramidal neurons in aging rabbits at a dose that facilitates associative learning.
    Brain research, 1990, Dec-03, Volume: 535, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Aging; Analysis of Variance; Animals; Catheterization; Conditioning, Eyelid; Dose-Response Relationship, Drug; Female; Flunarizine; Hippocampus; Neurons; Nifedipine; Nimodipine; Rabbits; Software

1990
Effects of calcium channel blockers on renal function in mice.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Animals; Calcium Channel Blockers; Chromium Radioisotopes; Cinnarizine; Edetic Acid; Female; Flunarizine; Glomerular Filtration Rate; Kidney; Mice; Mice, Inbred C3H; Nifedipine; Verapamil

1992
Tetrandrine: a novel calcium channel antagonist inhibits type I calcium channels in neuroblastoma cells.
    Neuropharmacology, 1991, Volume: 30, Issue:12A

    Topics: Alkaloids; Animals; Barium; Benzylisoquinolines; Calcium Channel Blockers; Flunarizine; Kinetics; Membrane Potentials; Mice; Neuroblastoma; Nifedipine; Tumor Cells, Cultured

1991
The long-term treatment with the Ca(2+)-antagonists nifedipine, verapamil, flunarizine and with the calmodulin antagonist trifluoperazine decreases the activity of 5-HT1 receptors in rat cerebral cortex and hippocampus.
    General pharmacology, 1991, Volume: 22, Issue:6

    Topics: Animals; Calcium Channel Blockers; Calmodulin; Cerebral Cortex; Flunarizine; Hippocampus; In Vitro Techniques; Kinetics; Male; Nifedipine; Rats; Rats, Inbred Strains; Serotonin Antagonists; Trifluoperazine; Verapamil

1991
Caffeine-induced contractions in rabbit isolated renal artery are differentially inhibited by calcium antagonists.
    European journal of pharmacology, 1991, Apr-24, Volume: 196, Issue:3

    Topics: Animals; Bepridil; Caffeine; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Fendiline; Flunarizine; Kinetics; Lidoflazine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Renal Artery; Verapamil

1991
Effects of verapamil, nifedipine and flunarizine on haemodynamics and regional blood flows in pentobarbitone-anaesthetized rats.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:5

    Topics: Anesthesia; Animals; Calcium Channel Blockers; Cardiac Output; Electrocardiography; Flunarizine; Heart Rate; Hemodynamics; Male; Nifedipine; Pentobarbital; Rats; Rats, Inbred Strains; Regional Blood Flow; Renal Circulation; Verapamil

1990
Increased toxicity of anthracycline antibiotics induced by calcium entry blockers in cultured cardiomyocytes.
    Toxicology and applied pharmacology, 1991, Mar-15, Volume: 108, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Calcium Channel Blockers; Cells, Cultured; Daunorubicin; Doxorubicin; Drug Resistance; Drug Synergism; Flunarizine; Heart; Nifedipine; Rats

1991
45Ca2+ movements induced by Ca2+ chloride in isolated rat aorta under K(+)-free conditions.
    European journal of pharmacology, 1991, Jan-17, Volume: 192, Issue:3

    Topics: Amiloride; Animals; Aorta, Thoracic; Benzothiazoles; Calcium; Calcium Chloride; Calcium Radioisotopes; Flunarizine; In Vitro Techniques; Indomethacin; Lanthanum; Lidocaine; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Piperidines; Potassium; Rats; Thiazoles; Vasoconstriction

1991
Influence of long-term treatment with the Ca2(+)-antagonists nifedipine, verapamil, flunarizine and with the calmodulin antagonist trifluoperazine on beta-adrenoceptors in rat cerebral cortex.
    General pharmacology, 1990, Volume: 21, Issue:1

    Topics: Animals; Calcium Channel Blockers; Calmodulin; Cerebral Cortex; Dihydroalprenolol; Flunarizine; Male; Membrane Fluidity; Membranes; Nifedipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Synaptosomes; Trifluoperazine; Verapamil

1990
Attenuation of the low-density-lipoprotein-activated phosphoinositide signalling system by calcium blockers in human lymphocytes.
    Clinical science (London, England : 1979), 1990, Volume: 78, Issue:5

    Topics: Calcium Channel Blockers; Cells, Cultured; Cholesterol, LDL; Diglycerides; Diltiazem; Dose-Response Relationship, Drug; Flunarizine; Humans; Lymphocytes; Molsidomine; Nifedipine; Phosphatidylinositols; Protein Kinase C; Verapamil

1990
Effects of the Ca2(+)-antagonists nifedipine, verapamil, flunarizine and of the calmodulin antagonist trifluoperazine on muscarinic cholinergic receptors in rat cerebral cortex.
    General pharmacology, 1990, Volume: 21, Issue:3

    Topics: Animals; Calcium Channel Blockers; Calmodulin; Cerebral Cortex; Flunarizine; Kinetics; Male; Nifedipine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Trifluoperazine; Verapamil

1990
Effects of calcium antagonists on biogenic amines in discrete brain areas.
    European journal of pharmacology, 1990, Jun-08, Volume: 181, Issue:3

    Topics: Animals; Biogenic Monoamines; Brain Chemistry; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Electrochemistry; Flunarizine; Male; Nifedipine; Rats; Rats, Inbred Strains; Verapamil

1990
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cinnarizine; Diltiazem; Flunarizine; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Phenytoin; Pheochromocytoma; Potassium; Rats; Sodium; Verapamil

1985
Muscarinic cholinergic enhancement of inositide turnover in cerebral nerve endings is not mediated by calcium uptake.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcimycin; Calcium; Carbachol; Cinnarizine; Flunarizine; Male; Nerve Endings; Nicotinic Acids; Nifedipine; Nimodipine; Phosphatidic Acids; Phosphatidylinositols; Rats; Rats, Inbred Strains; Verapamil; Veratridine

1986
[Mechanism of action of calcium antagonists in the treatment of vascular diseases].
    Wiener medizinische Wochenschrift (1946), 1986, Nov-30, Volume: 136, Issue:21-22

    Topics: Arterial Occlusive Diseases; Calcium; Calcium Channel Blockers; Cerebrovascular Circulation; Flunarizine; Humans; Ion Channels; Migraine Disorders; Muscle, Smooth, Vascular; Nifedipine

1986
Ethanol-induced component of 45Ca2+ uptake in PC12 cells is sensitive to Ca2+ channel modulating drugs.
    Brain research, 1987, Apr-28, Volume: 410, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cell Line; Diltiazem; Drug Interactions; Ethanol; Flunarizine; Ion Channels; Nifedipine; Verapamil

1987
Histamine stimulated synaptosomal Ca2+ uptake through activation of calcium channels.
    Biochemical and biophysical research communications, 1988, Jun-30, Volume: 153, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Bucladesine; Calcium; Cinnarizine; Cyclic AMP; Diltiazem; Flunarizine; Histamine; Ion Channels; Nifedipine; Rats; Synaptosomes; Verapamil

1988
Distinction of two components of passive Ca2+ transport into human erythrocytes by Ca2+ entry blockers.
    Biochimica et biophysica acta, 1989, May-19, Volume: 981, Issue:1

    Topics: Aminoquinolines; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability; Cobalt; Copper; Diltiazem; Erythrocyte Membrane; Flunarizine; Humans; Nifedipine; Vanadates; Verapamil

1989
Modification of tumour response by calcium antagonists in the SCVII/St tumour implanted at two different sites.
    International journal of radiation biology, 1989, Volume: 56, Issue:3

    Topics: Animals; Back; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Flunarizine; Hindlimb; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nifedipine; Radiation Tolerance; Rubidium; Verapamil

1989
Role of endothelium in the contractile response of rat aorta to alpha-adrenoceptor agonists.
    Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Calcium; Cinnarizine; Endothelium; Flunarizine; Guanfacine; Guanidines; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phenylacetates; Rats; Rats, Inbred Strains

1985
Calcium antagonists as radiation modifiers: site specificity in relation to tumor response.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5

    Topics: Animals; Calcium Channel Blockers; Combined Modality Therapy; Female; Flunarizine; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nifedipine; Radiation-Sensitizing Agents; Verapamil

1989
Effects of calcium entry blockers on human platelet metabolism measured by microcalorimetry.
    Human toxicology, 1989, Volume: 8, Issue:2

    Topics: Blood Platelets; Calcium Channel Blockers; Calorimetry; Cerebral Arteries; Diltiazem; Flunarizine; Humans; Muscle Relaxation; Nifedipine; Verapamil

1989
Different sensitivities for four calcium entry blockers of serotonin-, but not K+-induced contractions of isolated jugular vein and aorta of the rat.
    Pharmacology, 1989, Volume: 38, Issue:5

    Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Diltiazem; Flunarizine; Gallopamil; In Vitro Techniques; Jugular Veins; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Serotonin

1989
Selective modulation by membrane potential of the interaction of some calcium entry blockers with calcium channels in rat mesenteric artery.
    British journal of pharmacology, 1988, Volume: 95, Issue:1

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Flunarizine; In Vitro Techniques; Isradipine; Membrane Potentials; Membranes; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Oxadiazoles; Rats; Rats, Inbred Strains

1988
Calcium channel antagonists. Omega-conotoxin defines a new high affinity site.
    The Journal of biological chemistry, 1986, May-15, Volume: 261, Issue:14

    Topics: Animals; Binding, Competitive; Brain; Calcium Channel Blockers; Chick Embryo; Cinnarizine; Diltiazem; Flunarizine; Muscles; Nifedipine; Nitrendipine; Prenylamine; Rana pipiens; Synaptosomes; Time Factors; Verapamil

1986
Augmentation by calcium channel antagonists of general anaesthetic potency in mice.
    British journal of pharmacology, 1986, Volume: 88, Issue:4

    Topics: Anesthesia, General; Animals; Argon; Calcium Channel Blockers; Cinnarizine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Flunarizine; Male; Mice; Nifedipine; Nitrendipine; Pentobarbital; Time Factors; Verapamil

1986
[Facilitation of the onset of tetanic responses induced by 4-methylesculetol in amphibian isolated neuromuscular preparations].
    Acta vitaminologica et enzymologica, 1985, Volume: 7, Issue:3-4

    Topics: Acetylcholine; Animals; Calcium; Cinnarizine; Drug Interactions; Flunarizine; In Vitro Techniques; Muscle Contraction; Neuromuscular Junction; Nifedipine; Rana esculenta; Scopoletin; Synaptic Transmission; Umbelliferones

1985
Ineffectiveness of organic calcium channel blockers in antagonizing long-term potentiation.
    Brain research, 1986, Aug-06, Volume: 379, Issue:2

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Cinnarizine; Diazepam; Flunarizine; Guinea Pigs; Hippocampus; Neurons; Nifedipine; Nitrendipine; Reaction Time; Synaptic Transmission; Verapamil

1986
Mechanisms of flunarizine-induced vasodilation in the rabbit mesenteric artery.
    Circulation research, 1987, Volume: 61, Issue:3

    Topics: Animals; Biomechanical Phenomena; Caffeine; Calcium; Flunarizine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phosphatidic Acids; Phosphatidylinositols; Potassium; Rabbits; Vasodilation

1987
Studies of [3H]nitrendipine binding and KCl-induced calcium uptake in rat cortical synaptosomes.
    General pharmacology, 1985, Volume: 16, Issue:3

    Topics: Animals; Calcium; Calcium Channel Blockers; Cerebral Cortex; Cinnarizine; Flunarizine; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes

1985
The classification of calcium antagonists by the WHO expert committee: relevance in neurology.
    Cephalalgia : an international journal of headache, 1988, Volume: 8 Suppl 8

    Topics: Brain Diseases; Calcium Channel Blockers; Diltiazem; Flunarizine; Humans; Nifedipine; Verapamil

1988
Different effects of R 56865 and calcium entry blockers on K+- and noradrenaline-induced contractions and 45Ca uptake in rat aorta.
    European journal of pharmacology, 1988, Dec-13, Volume: 158, Issue:3

    Topics: Animals; Aorta; Benzothiazoles; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Flunarizine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Piperidines; Potassium; Rats; Rats, Inbred Strains; Thiazoles; Verapamil

1988
Aggravation of Parkinson's disease by cinnarizine.
    Journal of neurology, neurosurgery, and psychiatry, 1988, Volume: 51, Issue:1

    Topics: Animals; Caudate Nucleus; Cinnarizine; Dopamine; Flunarizine; Male; Nifedipine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Receptors, Dopamine

1988
Variable results of calcium blockade in post-ischaemic renal failure.
    European urology, 1988, Volume: 14, Issue:3

    Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Flunarizine; Ischemia; Kidney; Male; Nifedipine; Rats; Rats, Inbred Strains; Verapamil

1988
The effects of calcium channel blocking drugs on halothane initiation of malignant hyperthermia in MHS swine and on the established syndrome.
    Anaesthesia and intensive care, 1988, Volume: 16, Issue:2

    Topics: Anesthesia, General; Animals; Calcium Channel Blockers; Diltiazem; Flunarizine; Halothane; Malignant Hyperthermia; Nifedipine; Nisoldipine; Swine; Verapamil

1988
Verapamil as an apparent competitive antagonist of the serotonin receptor of rabbit isolated aorta.
    General pharmacology, 1986, Volume: 17, Issue:2

    Topics: Animals; Aorta, Thoracic; Binding, Competitive; Cinnarizine; Diltiazem; Flunarizine; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Receptors, Serotonin; Verapamil

1986
Nifedipine and flunarizine block amphetamine-induced behavioral stimulation in mice.
    Life sciences, 1986, Jun-30, Volume: 38, Issue:26

    Topics: Animals; Calcium Channel Blockers; Cinnarizine; Dextroamphetamine; Dose-Response Relationship, Drug; Flunarizine; Mice; Motor Activity; Nifedipine

1986
Polymorphonuclear leucocytes as a model of Ca++ and Mg++-dependent cellular activation. Effect of calcium entry blockers.
    International journal of tissue reactions, 1985, Volume: 7, Issue:4

    Topics: Calcimycin; Calcium; Calcium Channel Blockers; Cell Aggregation; Cinnarizine; Flunarizine; Glucuronidase; Humans; Kinetics; Magnesium; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nifedipine

1985
Isolated rat cardiac myocytes as an experimental model to study calcium overload: the effect of calcium-entry blockers.
    Life sciences, 1986, Mar-03, Volume: 38, Issue:9

    Topics: Animals; Calcium; Calcium Channel Blockers; Cinnarizine; Diltiazem; Flunarizine; Heart; Lidoflazine; Male; Myocardial Contraction; Myocardium; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Time Factors; Verapamil; Veratrine

1986
Pupillary and vascular effects of calcium antagonists in migraine.
    Cephalalgia : an international journal of headache, 1985, Volume: 5 Suppl 2

    Topics: Blood Pressure; Calcium Channel Blockers; Cinnarizine; Flunarizine; Humans; Migraine Disorders; Nifedipine; Pupil; Vasoconstriction; Verapamil

1985
Evaluation of calcium entry blockers in several models of immediate hypersensitivity.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:3

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acids; Bronchial Spasm; Calcium Channel Blockers; Cinnarizine; Diltiazem; Flunarizine; Guinea Pigs; Histamine Release; Hydroxyeicosatetraenoic Acids; Hypersensitivity, Immediate; Lipoxygenase; Male; Mast Cells; Nifedipine; Rats; Verapamil

1984
A calcium antagonist drug binding site in skeletal muscle sarcoplasmic reticulum: evidence for a calcium channel.
    Life sciences, 1983, Mar-21, Volume: 32, Issue:12

    Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Cinnarizine; Egtazic Acid; Flunarizine; Gallic Acid; Ion Channels; Muscle Contraction; Neuromuscular Junction; Nifedipine; Nitrendipine; Pyridines; Rabbits; Sarcoplasmic Reticulum; Verapamil

1983
Effect of calcium-entry blockers and divalent cations on noradrenaline-induced contractions of the rat anococcygeus muscle.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 271, Issue:1

    Topics: Animals; Calcium Channel Blockers; Cations; Cinnarizine; Cobalt; Diltiazem; Flunarizine; In Vitro Techniques; Male; Manganese; Muscle Contraction; Muscles; Nifedipine; Norepinephrine; Potassium; Rats; Sacrococcygeal Region

1984
Pharmacological protection against hypoxia-induced effects on medium-term memory in a two-way avoidance paradigm.
    Behavioural brain research, 1984, Volume: 14, Issue:2

    Topics: Animals; Avoidance Learning; Calcium Channel Blockers; Cerebral Cortex; Cinnarizine; Dose-Response Relationship, Drug; Flunarizine; Guinea Pigs; Hypoxia, Brain; Male; Memory; Mental Recall; Nicotinic Acids; Nifedipine; Nimodipine; Retention, Psychology; Vasodilation; Verapamil

1984
High affinity binding sites for [3H]-nitrendipine in rabbit uterine smooth muscle.
    Life sciences, 1984, Apr-30, Volume: 34, Issue:18

    Topics: Animals; Binding Sites; Calcium Channel Blockers; Cell Membrane; Cinnarizine; Depression, Chemical; Dose-Response Relationship, Drug; Female; Flunarizine; Muscle, Smooth; Nifedipine; Nitrendipine; Rabbits; Uterus; Verapamil

1984
Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:2

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cinnarizine; Cobalt; Dose-Response Relationship, Drug; Drug Synergism; Flunarizine; Guinea Pigs; Ileum; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyridines; Structure-Activity Relationship; Verapamil

1983
Calcium entry blockers and vascular smooth muscle heterogeneity.
    Federation proceedings, 1981, Volume: 40, Issue:14

    Topics: Animals; Calcium; Calcium Channel Blockers; Cinnarizine; Flunarizine; Gallopamil; Lidoflazine; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Verapamil

1981
Clinical use of calcium entry blockers.
    Federation proceedings, 1981, Volume: 40, Issue:14

    Topics: Angina Pectoris; Calcium Channel Blockers; Cinnarizine; Coronary Circulation; Coronary Vasospasm; Diltiazem; Flunarizine; Heart Rate; Humans; Lidoflazine; Nifedipine; Perhexiline; Verapamil

1981
Modulation of acetylcholine release in rat hippocampus by amino alcohols and Bay K 8644.
    Brain research, 1993, Nov-26, Volume: 629, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium; Cerebral Cortex; Choline; Corpus Striatum; Diltiazem; Dose-Response Relationship, Drug; Ethanolamine; Ethanolamines; Flunarizine; Hippocampus; In Vitro Techniques; Male; Nifedipine; Osmolar Concentration; Potassium Chloride; Propanolamines; Pyrrolidines; Rats; Rats, Inbred F344; Verapamil

1993
Calcium channel blockers improve hypoxia/hypoglycemia-induced impairment of rat hippocampal 2-deoxyglucose uptake in vitro after ethanol withdrawal.
    Brain research, 1995, Mar-06, Volume: 673, Issue:2

    Topics: Animals; Calcium Channel Blockers; Deoxyglucose; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; Flunarizine; Glutamic Acid; Hippocampus; Hypoglycemia; Hypoxia; Male; Nifedipine; Rats; Rats, Wistar; Substance Withdrawal Syndrome

1995
Effects of L-type calcium channel antagonists on the serotonin-depleting actions of MDMA in rats.
    Brain research, 1993, Feb-12, Volume: 603, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Calcium Channel Blockers; Cerebral Cortex; Flunarizine; Haloperidol; Hippocampus; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nifedipine; Rats; Rats, Sprague-Dawley; Seizures; Serotonin; Stereotyped Behavior; Verapamil

1993
Inhibition of endogenous acetylcholine release by blockade of voltage-dependent calcium channels in enteric neurons of the guinea-pig colon.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:5

    Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Colon; Electric Stimulation; Electrophysiology; Flunarizine; Guinea Pigs; In Vitro Techniques; Male; Neurons; Nifedipine; omega-Conotoxin GVIA; Peptides, Cyclic

1993
Metal ions affect neuronal membrane fluidity of rat cerebral cortex.
    Neurochemical research, 1994, Volume: 19, Issue:3

    Topics: Animals; Cations; Cerebral Cortex; Cyclic N-Oxides; Edetic Acid; Egtazic Acid; Electron Spin Resonance Spectroscopy; Flunarizine; Kinetics; Male; Membrane Fluidity; Metals; Neurons; Nicardipine; Nifedipine; Nimodipine; Rats; Rats, Sprague-Dawley; Spin Labels; Synaptosomes

1994
Effect of a Ca2+ entry blocker, nilvadipine, on hearing disturbances and equilibrium dysfunction caused by microcirculatory disorders of the rat inner ear.
    European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3

    Topics: Acoustic Stimulation; Action Potentials; Analysis of Variance; Animals; Calcium Channel Blockers; Cochlea; Ear, Inner; Flunarizine; Hearing Disorders; Laser-Doppler Flowmetry; Nifedipine; Rats; Rats, Wistar; Regional Blood Flow; Sensation Disorders; Ultraviolet Rays

1993
Effects of Ca2+ channel blockers on physical dependence on diazepam in mice.
    Life sciences, 1993, Volume: 53, Issue:22

    Topics: Animals; Brain; Calcium Channel Blockers; Carbolines; Diazepam; Diltiazem; Drug Interactions; Flunarizine; Male; Mice; Mice, Inbred ICR; Nifedipine; Receptors, GABA-A; Seizures; Substance-Related Disorders

1993
Radioprotective effects of calcium antagonists used alone or with other types of radioprotectors.
    Radiation research, 1993, Volume: 133, Issue:1

    Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Diltiazem; Dimethyl Sulfoxide; Drug Combinations; Female; Flunarizine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Radiation-Protective Agents; Verapamil; Zinc

1993
Protective effect of flunarizine and nifedipine alone and in combination with anticonvulsant drugs against PTZ-induced seizures in mice.
    Neuropharmacology, 1993, Volume: 32, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Female; Flunarizine; Male; Mice; Nifedipine; Pentylenetetrazole; Phenytoin; Seizures

1993
Effects of calcium antagonists nifedipine and flunarizine on phencyclidine-induced changes in the regional dopaminergic metabolism of the rat brain.
    Biochemical pharmacology, 1996, Jan-12, Volume: 51, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Mapping; Calcium Channel Blockers; Dopamine; Flunarizine; Hallucinogens; Homovanillic Acid; Male; Nifedipine; Phencyclidine; Rats; Rats, Inbred Strains

1996
[Direct evidence of a protective effect of calcium antagonists on the inner ear. Inhibition of a toxic increase in the calcium level in hair cells of the guinea pig].
    HNO, 1995, Volume: 43, Issue:12

    Topics: Animals; Calcium; Calcium Channel Blockers; Culture Techniques; Dose-Response Relationship, Drug; Female; Flunarizine; Guinea Pigs; Hair Cells, Auditory; Hair Cells, Auditory, Outer; Male; Membrane Potentials; Nifedipine; Potassium; Second Messenger Systems; Signal Transduction; Verapamil

1995
Effect of calcium antagonists on regional cerebral blood flow in transplanted rat brain tumors.
    Journal of neuro-oncology, 1996, Volume: 27, Issue:1

    Topics: Analysis of Variance; Animals; Brain; Brain Neoplasms; Calcium Channel Blockers; Cerebrovascular Circulation; Diltiazem; Flunarizine; Glioma; Male; Neoplasm Transplantation; Nifedipine; Nimodipine; Rats; Rats, Wistar; Verapamil

1996
Ca2+ channel blockade and the antielectroshock activity of NMDA receptor antagonists, CGP 40116 and CGP 43487, in mice.
    European journal of pharmacology, 1996, Sep-19, Volume: 312, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Excitatory Amino Acid Antagonists; Flunarizine; Male; Mice; Nicardipine; Nifedipine; Receptors, N-Methyl-D-Aspartate

1996
Anticonvulsant and adverse effects of MK-801, LY 235959, and GYKI 52466 in combination with Ca2+ channel inhibitors in mice.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Avoidance Learning; Benzodiazepines; Calcium Channel Blockers; Dizocilpine Maleate; Drug Interactions; Electroshock; Excitatory Amino Acid Antagonists; Flunarizine; Isoquinolines; Male; Mice; Motor Activity; Nicardipine; Nifedipine; Seizures

1997
Effect of 4-aminopyridine and 3,4-diaminopyridine on guinea-pig isolated ileum.
    Journal of autonomic pharmacology, 1997, Volume: 17, Issue:1

    Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Animals; Atropine; Calcium Channel Blockers; Diazoxide; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Female; Flunarizine; Guinea Pigs; Ileum; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Parasympathetic Nervous System; Parasympatholytics; Potassium Channels; Vasodilator Agents; Verapamil

1997
Differentiation of the inhibitory effects of calcium antagonists on abnormal behaviors induced by methamphetamine or phencyclidine.
    Pharmacology, 1998, Volume: 56, Issue:4

    Topics: Amygdala; Animals; Behavior, Animal; Calcium Channel Blockers; Caudate Nucleus; Central Nervous System Stimulants; Dopamine Uptake Inhibitors; Flunarizine; Injections, Intraperitoneal; Male; Methamphetamine; Microinjections; Motor Activity; Nicardipine; Nifedipine; Phencyclidine; Putamen; Rats; Rats, Wistar

1998
Effect of nilvadipine on the voltage-dependent Ca2+ channels in rat hippocampal CA1 pyramidal neurons.
    Brain research, 1998, Nov-30, Volume: 813, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Flunarizine; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar

1998
Effect of calcium antagonists on the response to noradrenaline in the whole and bisected rat vas deferens.
    Journal of autonomic pharmacology, 1998, Volume: 18, Issue:5

    Topics: Animals; Calcium Channel Blockers; Cromakalim; Diltiazem; Flunarizine; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Organ Culture Techniques; Papaverine; Rats; Rats, Wistar; Vas Deferens

1998
High sensitivity of immature GABAergic neurons to blockers of voltage-gated calcium channels.
    Brain research. Developmental brain research, 1999, Jun-08, Volume: 115, Issue:1

    Topics: Acetylcholine; Animals; Calcium Channel Blockers; Cell Death; Cells, Cultured; Cellular Senescence; Cycloheximide; Flunarizine; gamma-Aminobutyric Acid; Ion Channel Gating; Membrane Potentials; Neurons; Nifedipine; Rats; Rats, Sprague-Dawley

1999
Effect of voltage-dependent calcium channel blockers on ethanol-induced beta-endorphin release from hypothalamic neurons in primary cultures.
    Alcoholism, clinical and experimental research, 1999, Volume: 23, Issue:5

    Topics: Animals; beta-Endorphin; Calcium Channel Blockers; Calcium Channels; Calcium Channels, N-Type; Cell Survival; Cells, Cultured; Ethanol; Flunarizine; Hypothalamus; Neurons; Nifedipine; Rats; Rats, Sprague-Dawley; Synaptic Transmission

1999
Different effects of L-type and T-type calcium channel blockers on the hypnotic potency of triazolam and zolpidem in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:4

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, T-Type; Drug Interactions; Flunarizine; Hypnotics and Sedatives; Male; Nifedipine; Pyridines; Rats; Rats, Wistar; Sleep, REM; Triazolam; Zolpidem

1999
PMCA1 mRNA expression in rat aortic myocytes: a real-time RT-PCR study.
    Biochemical and biophysical research communications, 2000, Oct-05, Volume: 276, Issue:3

    Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cation Transport Proteins; Cattle; Cells, Cultured; Flunarizine; Gene Expression Regulation, Enzymologic; Imidazoles; Male; Muscle, Smooth; Nifedipine; Plasma Membrane Calcium-Transporting ATPases; Protein Isoforms; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Up-Regulation

2000
Subtypes of low voltage-activated Ca2+ channels in laterodorsal thalamic neurons: possible localization and physiological roles.
    Pflugers Archiv : European journal of physiology, 2001, Volume: 441, Issue:6

    Topics: Amiloride; Animals; Calcium Channel Blockers; Calcium Channels; Diuretics; Flunarizine; Ion Channel Gating; Kinetics; Lanthanum; Lateral Thalamic Nuclei; Membrane Potentials; Nickel; Nifedipine; Patch-Clamp Techniques; Rats

2001
Pharmacological involvement of the calcium channel blocker flunarizine in dopamine transmission at the striatum.
    Parkinsonism & related disorders, 2001, Volume: 8, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Calcium Channel Blockers; Calcium Channels, L-Type; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Flunarizine; Haloperidol; Male; Microinjections; Neostriatum; Nifedipine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Synapses; Synaptic Transmission

2001
Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons.
    Journal of neuroscience research, 2001, Aug-01, Volume: 65, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Benzothiadiazines; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flunarizine; Gene Expression Regulation, Developmental; Ion Channel Gating; Lanthanum; Macromolecular Substances; Mice; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nifedipine; omega-Conotoxins; Polyamines; Protein Subunits; Receptors, AMPA; Sodium; Sodium Channels; Sodium-Calcium Exchanger; Spermine; Tetrodotoxin

2001
Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:5

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Calcium; Calcium Channel Blockers; Choline O-Acetyltransferase; Electroretinography; Excitatory Amino Acid Agonists; Flunarizine; Intraocular Pressure; N-Methylaspartate; Neuroprotective Agents; Nifedipine; Parvalbumins; Rabbits; Rats; Rats, Wistar; Reperfusion Injury; Retina; RNA, Messenger; Sodium; Thy-1 Antigens; Vasodilator Agents

2002
Influence of agents affecting voltage-dependent calcium channels and dantrolene on the anticonvulsant action of the AMPA/kainate receptor antagonist LY 300164 in mice.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2002, Volume: 12, Issue:4

    Topics: Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Benzodiazepines; Calcium Channel Blockers; Calcium Channels; Dantrolene; Dose-Response Relationship, Drug; Drug Interactions; Flunarizine; Glafenine; Male; Mice; Nifedipine; Psychomotor Performance; Receptors, AMPA

2002
Ionic involvement and kinase activity on the mechanism of nongenomic action of thyroid hormones on 45Ca2+ uptake in cerebral cortex from young rats.
    Neuroscience research, 2007, Volume: 57, Issue:1

    Topics: Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flunarizine; In Vitro Techniques; Ion Channels; Nifedipine; Protein Kinases; Rats; Rats, Wistar; Thyroid Hormones; Time Factors

2007
Evidence for postsynaptic modulation of muscle contraction by a Drosophila neuropeptide.
    Peptides, 2008, Volume: 29, Issue:7

    Topics: Amiloride; Amino Acid Sequence; Animals; Calcium Channels, L-Type; Calcium Channels, T-Type; Dose-Response Relationship, Drug; Drosophila; Flunarizine; FMRFamide; Glutamic Acid; Larva; Molecular Sequence Data; Muscle Contraction; Nicardipine; Nifedipine; Receptors, Glutamate; Synaptic Transmission

2008
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
    Analytical chemistry, 2008, May-15, Volume: 80, Issue:10

    Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Glioma; Glutamic Acid; Lidocaine; Luminescence; Nickel; Nifedipine; Rats; Veratridine

2008
Vasodilator effects of flunarizine on retinal blood vessels in anesthetized rats.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:12

    Topics: Anesthesia; Animals; Blood Pressure; Dose-Response Relationship, Drug; Flunarizine; Male; Nifedipine; Rats; Rats, Wistar; Retinal Artery; Retinal Vein; Vasodilator Agents

2009
Comparative effects of T-type and L-type Ca(2+)-antagonists against noradrenaline-induced contractions of human vas deferens.
    BJU international, 2010, Volume: 106, Issue:4

    Topics: Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Flunarizine; Humans; Male; Mibefradil; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Pyrroles; Vas Deferens

2010
Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracellular calcium levels by selected L-type calcium channel blockers.
    Biochimica et biophysica acta, 2011, Volume: 1810, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Child; Drug Evaluation, Preclinical; Flunarizine; Humans; Intracellular Space; Membrane Glycoproteins; Molecular Chaperones; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Nicardipine; Nifedipine; Nimodipine; Potassium Chloride; RNA Interference; RNA, Small Interfering

2011
HOCl causes necrotic cell death in human monocyte derived macrophages through calcium dependent calpain activation.
    Biochimica et biophysica acta, 2012, Volume: 1823, Issue:2

    Topics: Calcimycin; Calcium; Calcium Channel Blockers; Calcium Ionophores; Calpain; Caspase 3; Cyclosporine; Dantrolene; Enzyme Inhibitors; Flunarizine; Humans; Hypochlorous Acid; Lysosomes; Macrophages; Membrane Potential, Mitochondrial; Muscle Relaxants, Central; Necrosis; Nifedipine; Verapamil

2012
T-type Ca²⁺ signalling downregulates MEK1/2 phosphorylation and cross-talk with the RAAS transcriptional response in cardiac myocytes.
    Journal of molecular and cellular cardiology, 2012, Volume: 53, Issue:2

    Topics: Animals; Calcium Signaling; Flunarizine; Fluoxetine; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mibefradil; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Nifedipine; Phosphorylation; Rats; Rats, Wistar; Receptors, Glucocorticoid; Renin-Angiotensin System; Spironolactone

2012
Novel pharmacological modulation of dystonic phenotypes caused by a gain-of-function mutation in the Na+ leak-current channel.
    Behavioural pharmacology, 2020, Volume: 31, Issue:5

    Topics: Animals; Boron Compounds; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dystonia; Ethoxzolamide; Flunarizine; Gain of Function Mutation; Gene Knockout Techniques; Ion Channels; Motor Disorders; Nifedipine; Nimodipine; Phenotype; Sodium Channels

2020