Compounds > nifedipine

nifedipine and fasudil

nifedipine has been researched along with fasudil in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's5 (35.71)29.6817
2010's8 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ito, K; Sasaki, Y; Seto, M; Shindo, K1
Ikegaki, I; Sasaki, Y; Uchida, T; Yamamoto, Y1
Bauer, J; Parekh, N1
Arikan, O; Ark, M; Büyükafsar, K; Korkmaz, B; Kubat, H; Ozveren, E; Songu-Mize, E; Yazici, G1
Archer, SL; Bonnet, SN; Haromy, A; Harry, G; Hashimoto, K; Kajimoto, H; Michelakis, ED; Moudgil, R; Nakanishi, T; Rebeyka, I; Thébaud, B1
Jin, L; Priviero, FB; Teixeira, CE; Webb, RC; Ying, Z1
Fan, YF; Fang, HC; Su, YS; Xie, PY; Zhang, ZJ; Zhang, ZY1
Behuliak, M; Bencze, M; Karen, P; Kuneš, J; Líšková, S; Petrová, M; Pintérová, M; Vaněčková, I; Zicha, J1
Calderón-Sánchez, E; González-Rodríguez, P; López-Barneo, J; Porras-González, C; Ureña, J1
Castellano, A; Egea-Guerrero, JJ; González-Montelongo, Mdel C; Muñoz-Sánchez, MÁ; Murillo-Cabezas, F; Porras-González, C; Ureña, J; Vilches-Arenas, A1
Dzialowski, EM; Greyner, H1
Behuliak, M; Bencze, M; Ergang, P; Kuneš, J; Polgárová, K; Vaněčková, I; Vavřínová, A; Zicha, J1
Behuliak, M; Hojná, S; Kadlecová, M; Kopkan, L; Vaněčková, I; Zicha, J1

Other Studies

14 other study(ies) available for nifedipine and fasudil

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Selective inhibition of myosin phosphorylation and tension of hyperplastic arteries by the kinase inhibitor HA1077.
    European journal of pharmacology, 1995, Mar-24, Volume: 276, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Carotid Arteries; Hyperplasia; In Vitro Techniques; Isoquinolines; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Myosins; Nifedipine; Phosphorylation; Potassium; Rabbits; Vasoconstriction

1995
The protein kinase inhibitor fasudil protects against ischemic myocardial injury induced by endothelin-1 in the rabbit.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Movement; Diltiazem; Electrocardiography; Endothelin-1; Enzyme Inhibitors; Heart Ventricles; Macrophages; Male; Microscopy; Myocardial Ischemia; Necrosis; Neutrophils; Nicorandil; Nifedipine; Papillary Muscles; Rabbits; Random Allocation; Vasodilator Agents

2000
Variations in cell signaling pathways for different vasoconstrictor agonists in renal circulation of the rat.
    Kidney international, 2003, Volume: 63, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Calcium Channel Blockers; Enzyme Inhibitors; Female; Gallic Acid; Indoles; Nifedipine; Norepinephrine; Pyridines; Rats; Rats, Wistar; Renal Circulation; Signal Transduction; Staurosporine; Vasoconstrictor Agents

2003
Effects of HA-1077 and Y-27632, two rho-kinase inhibitors, in the human umbilical artery.
    Cell biochemistry and biophysics, 2004, Volume: 41, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Biophysics; Calcium; Dose-Response Relationship, Drug; Humans; Models, Biological; Nifedipine; Potassium Chloride; Protein Isoforms; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Serotonin; Umbilical Arteries

2004
Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.
    Circulation, 2007, Apr-03, Volume: 115, Issue:13

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Ductus Arteriosus; Enzyme Activation; Enzyme Induction; Feedback, Physiological; Female; Fetal Heart; Gestational Age; Humans; Hydrogen Peroxide; Hypoplastic Left Heart Syndrome; Infant, Newborn; Intracellular Signaling Peptides and Proteins; Male; Mitochondria, Heart; Nifedipine; Organ Culture Techniques; Oxidation-Reduction; Oxygen; Partial Pressure; Phenylephrine; Protein Serine-Threonine Kinases; Pyridines; Rabbits; Reactive Oxygen Species; rho-Associated Kinases; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Superoxides; Vasoconstriction

2007
Comparative pharmacological analysis of Rho-kinase inhibitors and identification of molecular components of Ca2+ sensitization in the rat lower urinary tract.
    Biochemical pharmacology, 2007, Aug-15, Volume: 74, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amides; Animals; Atropine; Blotting, Western; Calcium Signaling; Dose-Response Relationship, Drug; Electric Stimulation; Endothelin-1; Enzyme Inhibitors; Guanine Nucleotide Dissociation Inhibitors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rho-Specific Guanine Nucleotide Dissociation Inhibitors; rhoA GTP-Binding Protein; Urethra; Urinary Bladder

2007
[Effects of rho-kinase inhibitor on cardiac hypertrophy of left ventricle in spontaneously hypertensive rats].
    Zhonghua yi xue za zhi, 2012, Dec-25, Volume: 92, Issue:48

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cardiomegaly; Heart Ventricles; Male; Nifedipine; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; RNA, Messenger

2012
Ca2+ sensitization and Ca2+ entry in the control of blood pressure and adrenergic vasoconstriction in conscious Wistar-Kyoto and spontaneously hypertensive rats.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium; Calcium Channel Agonists; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Male; Mesenteric Arteries; Nifedipine; Nitric Oxide; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic; rho-Associated Kinases; rhoA GTP-Binding Protein; Temperature; Vasoconstriction

2013
Low-dose combination of Rho kinase and L-type Ca(2+) channel antagonists for selective inhibition of depolarization-induced sustained arterial contraction.
    European journal of pharmacology, 2014, Jun-05, Volume: 732

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arteries; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; In Vitro Techniques; Male; Muscle Contraction; Myocytes, Cardiac; Myocytes, Smooth Muscle; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Wistar; rho-Associated Kinases; Vasodilator Agents

2014
Role of L-type Ca(2+) channels, sarcoplasmic reticulum and Rho kinase in rat basilar artery contractile properties in a new model of subarachnoid hemorrhage.
    Vascular pharmacology, 2015, Volume: 72

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Sarcoplasmic Reticulum; Subarachnoid Hemorrhage; Vasoconstriction

2015
In vitro oxygen exposure promotes maturation of the oxygen sensitive contraction in pre-term chicken ductus arteriosus.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2015, Volume: 188

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Chick Embryo; Chickens; Dinoprostone; Dose-Response Relationship, Drug; Ductus Arteriosus; Enzyme Inhibitors; Nifedipine; Nitric Oxide; Oxygen; Pyridines; rho-Associated Kinases; Time Factors; Vasoconstriction

2015
Ontogenetic changes in contribution of calcium sensitization and calcium entry to blood pressure maintenance of Wistar-Kyoto and spontaneously hypertensive rats.
    Journal of hypertension, 2015, Volume: 33, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arteries; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Gene Expression; Guanine Nucleotide Exchange Factors; Hypertension; Male; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Nifedipine; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rho Guanine Nucleotide Exchange Factors; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction

2015
Exaggerated blood pressure response to fasudil or nifedipine in hypertensive Ren-2 transgenic rats: role of altered baroreflex.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2019, Volume: 42, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Baroreflex; Blood Pressure; Calcium Channel Blockers; Hypertension; Male; Nifedipine; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin-Angiotensin System; Vasoconstriction

2019