nifedipine and e 4031

nifedipine has been researched along with e 4031 in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's7 (50.00)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD1
Nagashima, R; Nishikawa, T; Tobita, M1
Jia, L; Sun, H1
Sen, S; Sinha, N1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Bouman, LN; Bourier, J; van Ginneken, AC; Verheijck, EE1
Iost, N; Opincariu, M; Papp, JG; Szécsi, J; Varró, A; Virág, L1
Pan, YP; Wang, XL; Xu, XH1
Abe, J; Hamada, Y; Harada, T; Hashimoto, K; Horii, I; Sawada, Y; Shiotani, M1
Cheng, H; Hancox, JC; Orchard, CH; Smith, GL1
Bauriedl, J; Bussek, A; Lohmann, H; Ravens, U; Schmidt, M; Wettwer, E1
Dahlenborg, K; Kunze, A; Sartipy, P; Steel, D; Svedhem, S1
Bai, S; Cao, H; Dong, H; Jiang, J; Ma, Y; Pei, F; Tian, L; Yang, C; Zhao, Y1

Other Studies

14 other study(ies) available for nifedipine and e 4031

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit.
    Circulation research, 1995, Volume: 76, Issue:4

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium; Diastole; Electrophysiology; Female; In Vitro Techniques; Male; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Piperidines; Pyridines; Rabbits; Sinoatrial Node

1995
Delayed rectifier potassium current in undiseased human ventricular myocytes.
    Cardiovascular research, 1998, Volume: 40, Issue:3

    Topics: Action Potentials; Adult; Anti-Arrhythmia Agents; Barium Compounds; Cadmium; Calcium Channel Blockers; Chlorides; Female; Humans; Male; Middle Aged; Myocardium; Nifedipine; Patch-Clamp Techniques; Piperidines; Pyridines; Signal Processing, Computer-Assisted; Sodium-Potassium-Exchanging ATPase

1998
[High throughput screening method of potassium channel regulators].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:2

    Topics: 4-Aminopyridine; Animals; Barbiturates; Calcium Channel Blockers; Cromakalim; Isoxazoles; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; PC12 Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Quinidine; Rats

2004
Practical application of guinea pig telemetry system for QT evaluation.
    The Journal of toxicological sciences, 2005, Volume: 30, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Bepridil; Cisapride; Disease Models, Animal; Electrocardiography; Guinea Pigs; Haloperidol; Heart; Humans; Injections, Intravenous; Long QT Syndrome; Male; Nifedipine; Pimozide; Piperidines; Pyridines; Quinidine; Reproducibility of Results; Telemetry; Terfenadine; Thioridazine

2005
Acidosis inhibits spontaneous activity and membrane currents in myocytes isolated from the rabbit atrioventricular node.
    Journal of molecular and cellular cardiology, 2009, Volume: 46, Issue:1

    Topics: Acidosis; Animals; Atrioventricular Node; Calcium Channels, L-Type; Electrophysiology; Hydrogen-Ion Concentration; Ions; Male; Myocytes, Cardiac; Nifedipine; Patch-Clamp Techniques; Piperidines; Pyridines; Rabbits; Sensitivity and Specificity; Temperature

2009
Cardiac tissue slices with prolonged survival for in vitro drug safety screening.
    Journal of pharmacological and toxicological methods, 2012, Volume: 66, Issue:2

    Topics: 4-Aminopyridine; Action Potentials; Animal Testing Alternatives; Animals; Animals, Laboratory; Anti-Arrhythmia Agents; Calcium Channel Blockers; Carbenoxolone; Disease Models, Animal; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Male; Nifedipine; Piperidines; Potassium Channel Blockers; Pyridines; Rats; Rats, Wistar; Risk Assessment; Toxicity Tests

2012
Non-Invasive Acoustical sensing of Drug-Induced Effects on the Contractile Machinery of Human Cardiomyocyte Clusters.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Biosensing Techniques; Cell Line; Cytochalasin D; Humans; Isoproterenol; Myocytes, Cardiac; Nifedipine; Piperidines; Pyridines; Quartz Crystal Microbalance Techniques

2015
Chemical-defined and albumin-free generation of human atrial and ventricular myocytes from human pluripotent stem cells.
    Stem cell research, 2017, Volume: 19

    Topics: Action Potentials; Antioxidants; Cell Culture Techniques; Cell Differentiation; Cell Line; COUP Transcription Factor II; Culture Media; Homeodomain Proteins; Humans; Induced Pluripotent Stem Cells; Microscopy, Fluorescence; Myocytes, Cardiac; Nifedipine; Patch-Clamp Techniques; Piperidines; Pluripotent Stem Cells; Pyridines; Tretinoin

2017