nifedipine and doxazosin

nifedipine has been researched along with doxazosin in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's12 (44.44)18.2507
2000's7 (25.93)29.6817
2010's6 (22.22)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Sen, S; Sinha, N1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Donnelly, R; Elliott, HL; Howie, CA; Meredith, PA; Reid, JL2
Donnelly, R; Elliott, HL; Howie, CA; Reid, JL; Sumner, DJ1
Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL1
Alabaster, VA; Solca, AM1
Canessa, ML; DeFronzo, RA; Giordano, M; Matsuda, M; Sanders, L1
Canessa, ML; Castellino, P; DeFronzo, RA; Giordano, M; Sanders, LR1
Alarayyed, NA; Betteridge, DJ; Cooper, MB; Prichard, BN; Smith, CC1
Canessa, ML; Castellino, P; DeFronzo, RA; Giordano, M; Solini, A1
Iversen, BM; Kvam, FI; Ofstad, J1
Bialy-Golan, A; Brenner, S; Shachar, E; Srebrnik, A1
Beaman, M; D'Souza, RJ; Hamilton-Wood, C; Nicholls, AJ; Pearson, ER1
Hughes, PL; Oo, T; Soni, BM; Vaidyanathan, S1
Kompaniets, OG; Pokrovskii, VM1
Eto, M; Fukagawa, A; Imanishi, A; Latifpour, J; Yamamoto, Y; Yono, M; Yoshida, M2
Caça, I; Cınar, Y; Mehmet Türkcü, F; Sahin, A; Yıldırım, A; Yüksel, H1
Cang, H; Gong, Y; He, M; Li, Y; Liang, D; Liu, G; Pan, Y; Shi, J; Wang, W; Zhang, H; Zhang, S1
De Angelis, MV; Di Stefano, V; Onofrj, M; Rispoli, MG1

Reviews

2 review(s) available for nifedipine and doxazosin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
New drugs for hypertension--variations on old themes.
    Drug and therapeutics bulletin, 1991, Mar-18, Volume: 29, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Delayed-Action Preparations; Dihydropyridines; Doxazosin; Humans; Hypertension; Isradipine; Nifedipine; Prazosin; Verapamil

1991

Trials

7 trial(s) available for nifedipine and doxazosin

ArticleYear
Vascular pressor responses in treated and untreated essential hypertension.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Doxazosin; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Peptidyl-Dipeptidase A; Phenylephrine; Prazosin; Reflex; Regional Blood Flow; Renin

1990
Dose-response clarification in early drug development.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Doxazosin; Enalapril; Humans; Hypertension; Nifedipine; Prazosin

1991
The pharmacodynamics and pharmacokinetics of the combination of nifedipine and doxazosin.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:3

    Topics: Adult; Blood Pressure; Doxazosin; Drug Therapy, Combination; Heart Rate; Humans; Liver Circulation; Male; Nifedipine; Single-Blind Method

1993
Effect of alpha-adrenergic blockers, ACE inhibitors, and calcium channel antagonists on renal function in hypertensive non-insulin-dependent diabetic patients.
    Nephron, 1996, Volume: 72, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Captopril; Diabetes Mellitus, Type 2; Doxazosin; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Hypertension; Kidney; Kidney Function Tests; Male; Middle Aged; Nifedipine; Proteinuria

1996
Na+/Li+ and Na+/H+ countertransport activity in hypertensive non-insulin-dependent diabetic patients: role of insulin resistance and antihypertensive treatment.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:11

    Topics: Adult; Antihypertensive Agents; Antiporters; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Doxazosin; Erythrocytes; Female; Glucose; Glucose Clamp Technique; Humans; Hypertension; Insulin; Lithium; Male; Middle Aged; Nifedipine; Sodium; Sodium-Hydrogen Exchangers; Triglycerides

1997
Assessment of therapeutic drug efficiency.
    Bulletin of experimental biology and medicine, 2008, Volume: 145, Issue:6

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Doxazosin; Heart Rate; Humans; Nifedipine; Treatment Outcome

2008
Effects of doxazosin mesylate versus nifedipine on blood pressure variability in hypertensive patients: a randomized crossover study (SIMILAR).
    Blood pressure monitoring, 2019, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cross-Over Studies; Doxazosin; Essential Hypertension; Female; Humans; Male; Middle Aged; Nifedipine; Young Adult

2019

Other Studies

18 other study(ies) available for nifedipine and doxazosin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Combination of nifedipine and doxazosin in essential hypertension.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:4

    Topics: Aged; Analysis of Variance; Angiotensin II; Antihypertensive Agents; Blood Pressure; Doxazosin; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Phenylephrine; Prazosin

1992
Lack of differential inhibition by nifedipine of pressor responses induced by alpha 1- and alpha 2-adrenoceptor agonists and by angiotensin II in anaesthetized cats.
    Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10

    Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Blood Pressure; Cats; Doxazosin; Male; Muscle, Smooth, Vascular; Nifedipine; Nordefrin; Phenylephrine; Prazosin; Vasoconstriction; Yohimbine

1985
Effects of angiotensin-converting enzyme inhibitors, Ca2+ channel antagonists, and alpha-adrenergic blockers on glucose and lipid metabolism in NIDDM patients with hypertension.
    Diabetes, 1995, Volume: 44, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Captopril; Cholesterol; Diabetes Mellitus, Type 2; Doxazosin; Fatty Acids, Nonesterified; Female; Glucose; Glycated Hemoglobin; Humans; Hypertension; Insulin; Lipid Metabolism; Lipids; Male; Middle Aged; Nifedipine

1995
In vitro adrenaline and collagen-induced mobilization of platelet calcium and its inhibition by naftopidil, doxazosin and nifedipine.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Aequorin; Analysis of Variance; Blood Platelets; Calcium; Calcium Channel Blockers; Collagen; Dose-Response Relationship, Drug; Doxazosin; Drug Interactions; Epinephrine; Fibrinogen; Humans; In Vitro Techniques; Luminescent Measurements; Middle Aged; Naphthalenes; Nifedipine; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors

1997
Effects of antihypertensive drugs on autoregulation of RBF and glomerular capillary pressure in SHR.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Capillaries; Doxazosin; Enalapril; Homeostasis; Hypertension; Kidney; Kidney Glomerulus; Male; Nifedipine; Rats; Rats, Inbred SHR; Regional Blood Flow; Renal Circulation; Verapamil

1998
"Two-step" drug-induced bullous pemphigoid.
    International journal of dermatology, 1998, Volume: 37, Issue:12

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Doxazosin; Female; Humans; Middle Aged; Nifedipine; Pemphigoid, Bullous

1998
Hypertensive encephalopathy and nephrotic syndrome: a possible link?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:7

    Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Azathioprine; Brain Diseases; Calcium Channel Blockers; Diuretics; Doxazosin; Female; Furosemide; Headache; Humans; Hypertension; Immunosuppressive Agents; Magnetic Resonance Imaging; Middle Aged; Nephrotic Syndrome; Nifedipine; Prednisolone; Seizures; Visual Acuity

1999
Recurrent autonomic dysreflexia due to chronic aortic dissection in an adult male with cervical spinal cord injury.
    TheScientificWorldJournal, 2008, Jun-13, Volume: 8

    Topics: Adrenergic alpha-Antagonists; Aortic Rupture; Autonomic Dysreflexia; Calcium Channel Blockers; Cervical Vertebrae; Chronic Disease; Doxazosin; Humans; Male; Middle Aged; Nifedipine; Recurrence; Spinal Cord Injuries

2008
Molecular mechanisms regulating urogenital expression of nitric oxide synthase in spontaneously hypertensive rats.
    Life sciences, 2009, Aug-12, Volume: 85, Issue:7-8

    Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Doxazosin; Gene Expression; Gene Expression Profiling; Hypertension; Male; Nifedipine; Nitric Oxide Synthase; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; Urogenital System

2009
Identification of potential therapeutic targets in hypertension-associated bladder dysfunction.
    BJU international, 2010, Volume: 105, Issue:6

    Topics: Analysis of Variance; Animals; Antihypertensive Agents; Doxazosin; Gene Expression; Gene Expression Profiling; Hypertension; Male; Microarray Analysis; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Urinary Bladder Diseases

2010
Diagnosis of malignant hypertension with ocular examination: a child case.
    Seminars in ophthalmology, 2014, Volume: 29, Issue:1

    Topics: Antihypertensive Agents; Blood Pressure; Child; Doxazosin; Drug Therapy, Combination; Enalapril; Female; Fluorescein Angiography; Humans; Hypertension, Malignant; Intraocular Pressure; Nifedipine; Papilledema; Retinal Hemorrhage; Tomography, Optical Coherence; Tonometry, Ocular; Vasodilator Agents; Vesico-Ureteral Reflux; Visual Acuity

2014
Tumour-like presentation of atypical posterior reversible encephalopathy syndrome with prominent brainstem involvement.
    BMJ case reports, 2020, Jan-08, Volume: 13, Issue:1

    Topics: Antihypertensive Agents; Brain Stem; Calcium Channel Blockers; Diagnosis, Differential; Doxazosin; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nifedipine; Posterior Leukoencephalopathy Syndrome; Ramipril; White Matter

2020