nifedipine and digoxin

nifedipine has been researched along with digoxin in 94 studies

Research

Studies (94)

Timeframe	Studies, this research(%)	All Research%
pre-1990	47 (50.00)	18.7374
1990's	20 (21.28)	18.2507
2000's	13 (13.83)	29.6817
2010's	14 (14.89)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Andersson, KE; Mikkelsen, E; Pedersen, OL	2
Schenk, KE	1
Mikkelsen, E	1
Brecht, K; Gebert, G; Nguyen-Duong, H	1
Dück, K; Haustein, KO; Richard, F; Winkler, U	1
Bagni, B; Degli Uberti, EC; Ferlini, M; Montanari, L; Portaluppi, F; Vergnani, L	1
Dichtchekenian, V; Gisiger, S; Heimann, JC; Marcondes, M; Quental, I; Santos, SR	1
Cholewa, M; Dryjański, T; Gawor, Z; Górski, L; Kaczkowska-Marusik, E; Kuś, W; Markiewicz, K	1
Christensen, C	1
Berkovskiĭ, ML; Khrustalev, OA	1
Bechler-Lisińska, J; Cholewa, M; Górski, L; Markiewicz, K	1
Orynchak, MA	2
Akera, T; Brody, TM; Kennedy, RH; Seifen, E	1
Schwartz, JB	2
Abernethy, DR	1
Ahmad, A; Bloom, S	1
Bechler-Lisińska, J; Broks-Bratkowska, B; Cholewa, M; Dryjański, T; Gawor, Z; Górski, L; Markiewicz, K	1
Crawford, MH; O'Rourke, RA; Vittitoe, JA; Wilson, RS	1
Aronoff, GR; Fineberg, NS; Luft, FC; Weinberger, MH	1
Balzan, S; Clerico, A; Del Chicca, MG; Fommei, E; Gazzetti, P; Genovesi-Ebert, A; Ghione, S; Giaconi, S; Marabotti, C; Palombo, C	1
Brandt, NR; Caswell, AH; Kawamoto, RM	1
Suzuki, K	1
Jankowski, A; Karwowski, J; Marzec, A; Nartowicz, E	1
Dylewicz, P; Hutt, HJ; Kirch, W; Ohnhaus, EE	1
Kirch, W; Ohnhaus, EE; Santos, SR; Stenzel, J	1
Dylewicz, P; Hutt, HJ; Kirch, W; Ohnhaus, EE; Santos, SR; Stenzel, J	1
Maiorov, NI; Solov'ev, VV; Sukhorukova, ES	1
Dalla-Volta, S; Fasoli, G; Scognamiglio, R; Visintin, L	1
Garty, M; Ilfeld, D; Pitlik, S; Rosenfeld, JB; Shamir, E	1
Hvidt, S; Kjoer, K; Klitgaard, NA; Madsen, JL; Pedersen, KE	1
Jones, EM; Kasmer, RJ	1
At'kov, OIu; Kassirskiĭ, SG; Ordian, MM; Sobol', IuS	1
Breimer, DD; Hillers, J; Kleinbloesem, CH; Moolenaar, AJ; van Brummelen, P	1
Kenny, J	1
Dylewicz, P; Gräf, KJ; Hutt, HJ; Kirch, W; Ohnhaus, EE	1
Granit, L; Koren, G; Levy, M; Zylber-Katz, E	1
Kuhlmann, J	1
Koren, G	1
Heidemann, H; Hutt, HJ; Janisch, HD; Kirch, W; Ohnhaus, EE; Rämsch, K	1
Aust, PE; Belz, GG; Munkes, R	1
Hess, T; Riesen, W; Salzmann, R; Scholtysik, G	1
Moenning, SP	1
Bornstein, A; Dalal, P; Michaelson, S; Novack, S; Tischler, J	1
Buch, J; Hansen, PB; Rasmussen, OO; Steiness, E; Waldorff, S	1
Bellinetto, A; Lessem, J	1
Balestrazzi, M; Chiarappa, R; De Cesaris, R; Ranieri, G	1
Akers, S; Raizner, A; Schwartz, JB	1
Migliore, PJ; Schwartz, JB	1
Fondacaro, JD; Jacobson, ED; Walus, KM	1
Bracchetti, D; Cantelli, I; Naccarella, F; Parchi, C; Pavesi, PC	1
Dorph-Pedersen, A; Hvidt, S; Kjaer, K; Klitgaard, NA; Nielsen-Kudsk, F; Pedersen, KE	1
Halawa, B; Mazurek, W	1
Coats, AJ	1
Arnold, AE; Klein, LJ; Reichert, CL	1
Manyari, DE; Yunus, A	1
Maitai, CK; Munenge, RW; Njoroge, DK	1
Bliesath, H; Hartmann, M; Huber, R; Radtke, HW; Steinijans, VW; Wurst, W; Zech, K	1
Dalla Volta, S; Fasoli, G; Nistri, S; Rahimtoola, SH; Scognamiglio, R	1
Bonow, RO	1
Lou, ZJ; Sun, XL; Zhu, GL	1
Ayhan, A; Yapar, EG	1
Kokwaro, GO	1
Chen, J; Chen, Z; Gao, R; Kuo, W; Tao, S; Xu, Y; Yao, K; Yu, A	1
Högemann, A; Jonkman, JH; Lins, R; Sennewald, R; van Heiningen, PN; van Lier, JJ	1
Doris, PA; Kähönen, M; Kalliovalkama, J; Pekki, A; Pörsti, I; Tolvanen, JP; Voipio, J; Wu, X; Ylitalo, P	1
Grayburn, PA	1
Katoh, M; Nakajima, M; Yamazaki, H; Yokoi, T	1
Goto, Y; Higuchi, S; Minemoto, M; Ohdo, S; Suematsu, F; Yukawa, E; Yukawa, M	1
Horinouchi, M; Komada, F; Nishiguchi, K; Ohmoto, N; Ohnishi, N; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y; Yokoyama, T	1
Karlstadt, RG; Walker, K	1
Camara, AK; Chen, Q; Rhodes, SS; Riess, ML; Ropella, KM; Stowe, DF	1
Abrams, R; Guo, L; Kolaja, KL; Qian, JY; Sanders, MJ; Tang, HM; Weiser, T	1
Baryshnikov, SG; Golovina, VA; Hamlyn, JM; Linde, CI; Papparella, I; Pulina, MV; Zulian, A	1

Reviews

8 review(s) available for nifedipine and digoxin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Interaction between calcium antagonists and digoxin]. Ugeskrift for laeger, 1991, Apr-22, Volume: 153, Issue:17 Topics: Atrial Fibrillation; Calcium Channel Blockers; Digoxin; Diltiazem; Drug Interactions; Humans; Nifedipine; Verapamil	1991
The pharmacokinetic profile of amlodipine. American heart journal, 1989, Volume: 118, Issue:5 Pt 2 Topics: Administration, Oral; Aging; Amlodipine; Angina Pectoris; Animals; Biological Availability; Calcium Channel Blockers; Cimetidine; Digoxin; Drug Interactions; Half-Life; Humans; Injections, Intravenous; Kidney Diseases; Liver Cirrhosis; Nifedipine	1989
Digoxin and nifedipine. The American journal of cardiology, 1985, May-17, Volume: 55, Issue:12 Topics: Absorption; Administration, Oral; Cardiomyopathies; Digoxin; Drug Interactions; Electrophysiology; Glomerular Filtration Rate; Humans; Kinetics; Nifedipine	1985
Calcium channel blocking agents and the heart. British medical journal (Clinical research ed.), 1985, Oct-26, Volume: 291, Issue:6503 Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Vasospasm; Digoxin; Diltiazem; Heart Block; Heart Diseases; Heart Rate; Humans; Hypertension; Nifedipine; Verapamil	1985
Digitalis toxicity: a review of the literature. Indiana medicine : the journal of the Indiana State Medical Association, 1984, Volume: 77, Issue:11 Topics: Absorption; Arrhythmias, Cardiac; Digitalis Glycosides; Digoxin; Heart; Humans; Kinetics; Male; Nifedipine; Probability; Verapamil	1984
Lack of pantoprazole drug interactions in man. International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:8 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin	1994
Vasodilator therapy for chronic aortic and mitral regurgitation. The American journal of the medical sciences, 2000, Volume: 320, Issue:3 Topics: Aortic Valve Insufficiency; Chronic Disease; Digoxin; Heart Ventricles; Hemodynamics; Humans; Mitral Valve Insufficiency; Nifedipine; Survival Rate; Vasodilator Agents	2000

Trials

14 trial(s) available for nifedipine and digoxin

Article	Year
[Results of conventional treatment of severe congestive heart failure with vasodilators]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1992, Volume: 45, Issue:11-12 Topics: Adult; Aged; Captopril; Digoxin; Drug Administration Schedule; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Time Factors; Vasodilator Agents	1992
[Effect of vasodilator agents on the character and incidence of cardiac arrhythmia in chronic heart failure]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1990, Mar-01, Volume: 45, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Atrial Fibrillation; Captopril; Cardiac Output; Coronary Disease; Digoxin; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Furosemide; Heart Block; Heart Failure; Heart Valve Diseases; Heart Ventricles; Humans; Isosorbide; Male; Middle Aged; Nifedipine; Tachycardia; Vasodilator Agents	1990
Effects of amlodipine on steady-state digoxin concentrations and renal digoxin clearance. Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:1 Topics: Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Digoxin; Drug Interactions; Electrocardiography; Humans; Kidney; Male; Nifedipine	1988
[Evaluation of the effect of nifedipine in patients with chronic congestive heart failure]. Kardiologia polska, 1989, Volume: 32 Suppl 2 Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Digoxin; Diuresis; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Time Factors	1989
Effect of digoxin and vasodilators on left ventricular function in aortic regurgitation. International journal of cardiology, 1989, Volume: 23, Issue:3 Topics: Adult; Analysis of Variance; Aortic Valve Insufficiency; Digoxin; Echocardiography; Exercise Test; Heart Ventricles; Humans; Hydralazine; Male; Middle Aged; Nifedipine; Stroke Volume	1989
Effects of oral calcium, potassium, digoxin, and nifedipine on natriuresis in normal humans. American journal of hypertension, 1989, Volume: 2, Issue:1 Topics: Administration, Oral; Adult; Blood Pressure; Calcium; Digoxin; Humans; Male; Natriuresis; Nifedipine; Potassium; Reference Values; Sodium Chloride; Urine	1989
[Interaction between digoxin and nifedipine in the pharmacokinetic phase]. Kardiologia polska, 1987, Volume: 30 Suppl Topics: Adolescent; Adult; Clinical Trials as Topic; Digoxin; Humans; Male; Metabolic Clearance Rate; Nifedipine; Time Factors	1987
Influence of nisoldipine on haemodynamic effects and plasma levels of digoxin. British journal of clinical pharmacology, 1986, Volume: 22, Issue:2 Topics: Adult; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Digoxin; Double-Blind Method; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Nisoldipine; Pulse	1986
Interaction between digoxin and nifedipine at steady state in patients with atrial fibrillation. Therapeutic drug monitoring, 1985, Volume: 7, Issue:4 Topics: Adult; Aged; Atrial Fibrillation; Clinical Trials as Topic; Digoxin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nifedipine	1985
Digoxin plasma concentrations and nifedipine. Lancet (London, England), 1981, Apr-11, Volume: 1, Issue:8224 Topics: Adult; Aged; Clinical Trials as Topic; Digoxin; Double-Blind Method; Drug Interactions; Humans; Middle Aged; Nifedipine; Pyridines; Random Allocation; Verapamil	1981
Effect of nifedipine on serum digoxin concentration and renal digoxin clearance. Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:1 Topics: Adult; Blood Pressure; Digoxin; Drug Interactions; Heart Rate; Humans; Kidney; Male; Nifedipine	1984
Lack of pantoprazole drug interactions in man. International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:8 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin	1994
Nifedipine in asymptomatic patients with severe aortic regurgitation and normal left ventricular function. The New England journal of medicine, 1994, Sep-15, Volume: 331, Issue:11 Topics: Adult; Aortic Valve Insufficiency; Chronic Disease; Digoxin; Female; Follow-Up Studies; Heart Valve Prosthesis; Humans; Male; Nifedipine; Stroke Volume; Ventricular Function, Left	1994
Pharmacokinetic drug interaction studies with candesartan cilexetil. Journal of human hypertension, 1997, Volume: 11 Suppl 2 Topics: Adolescent; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Digoxin; Drug Interactions; Female; Glyburide; Humans; Hydrochlorothiazide; Male; Middle Aged; Nifedipine; Tetrazoles; Warfarin	1997

Other Studies

73 other study(ies) available for nifedipine and digoxin

Article	Year
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Effects of digoxin on isolated human peripheral arteries and veins. Acta pharmacologica et toxicologica, 1979, Volume: 45, Issue:4 Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Arteries; Calcium; Digoxin; Drug Synergism; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium; Veins	1979
[Use of nifedipine and nitroglycerin during exercise therapy in patients with myocardial infarct. Clinical and hemodynamic studies]. Fortschritte der Medizin, 1978, Mar-16, Volume: 96, Issue:10 Topics: Angina Pectoris; Blood Pressure; Cardiac Complexes, Premature; Cardiac Output; Digoxin; Exercise Therapy; Heart Rate; Humans; Myocardial Infarction; Nifedipine; Nitroglycerin; Pulse; Pyridines	1978
Effects of digoxin on islated human mesenteric vessels. Acta pharmacologica et toxicologica, 1979, Volume: 45, Issue:1 Topics: Aged; Calcium; Digoxin; Female; Humans; Male; Mesenteric Arteries; Mesenteric Veins; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Potassium	1979
Effects of digoxin in isolated human pulmonary vessels. Acta pharmacologica et toxicologica, 1979, Volume: 45, Issue:2 Topics: Adult; Aged; Digoxin; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Potassium; Pulmonary Artery; Pulmonary Veins	1979
[The effects of electric, ionic, hormonal, and pharmacological stimulation on the function of arteries and veins and their modification by Nifedipin (Adalat)]. Die Medizinische Welt, 1975, Sep-05, Volume: 26, Issue:36 Topics: Animals; Arteries; Calcium; Cattle; Digoxin; Electric Stimulation; Epinephrine; Nifedipine; Nitrates; Norepinephrine; Potassium; Pyridines; Stimulation, Chemical; Veins	1975
The reactivity of peripheral vessels of normo- and hypertensives. International journal of clinical pharmacology, therapy, and toxicology, 1992, Volume: 30, Issue:6 Topics: Adenosine Triphosphatases; Adult; Blood Pressure; Blood Proteins; Cardenolides; Digoxin; Erythrocyte Membrane; Female; Forearm; Heart Rate; Humans; Hypertension; Male; Nifedipine; Renin; Saponins; Sodium-Potassium-Exchanging ATPase; Vascular Resistance	1992
Differences in blood pressure regulation of congestive heart failure, before and after treatment, correlate with changes in the circulating pattern of atrial natriuretic peptide. European heart journal, 1992, Volume: 13, Issue:7 Topics: Aged; Atrial Natriuretic Factor; Blood Pressure; Cardiotonic Agents; Digoxin; Drug Therapy, Combination; Female; Furosemide; Gated Blood-Pool Imaging; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Nifedipine; Nitrates; Ventricular Function, Left	1992
Higher salt consumption, digoxin-like factor, and nifedipine response are associated with salt sensitivity in essential hypertension. American journal of hypertension, 1992, Volume: 5, Issue:10 Topics: Adult; Blood Pressure; Blood Proteins; Cardenolides; Diet, Sodium-Restricted; Digoxin; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Saponins; Sodium Chloride	1992
[Use of peripheral vasodilator agents corbaton and corinfar combined with digoxin in patients with congestive heart failure of rheumatic etiology]. Kardiologiia, 1990, Volume: 30, Issue:12 Topics: Adult; Digoxin; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Molsidomine; Nifedipine; Rheumatic Heart Disease	1990
[Evaluation of the effectiveness of calcium antagonists combined with digoxin and furosemide in hypertension complicated by circulatory insufficiency in elderly patients]. Klinicheskaia meditsina, 1990, Volume: 68, Issue:7 Topics: Aged; Digoxin; Drug Therapy, Combination; Furosemide; Heart Failure; Hemodynamics; Humans; Hypertension; Nifedipine	1990
Effects of BAY K-8644 on inotropic and arrhythmogenic actions of digoxin. European journal of pharmacology, 1986, May-13, Volume: 124, Issue:1-2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Arrhythmia Agents; Calcimycin; Calcium; Digoxin; Glycosides; Guinea Pigs; In Vitro Techniques; Myocardial Contraction; Nifedipine	1986
Sodium pump and calcium channel modulation of Mg-deficiency cardiomyopathy. The American journal of cardiovascular pathology, 1989, Volume: 2, Issue:4 Topics: Animals; Calcium; Calcium Channels; Cardiomyopathies; Cricetinae; Digoxin; Dose-Response Relationship, Drug; Heart; Magnesium; Magnesium Deficiency; Male; Mesocricetus; Myocardium; Nifedipine; Sodium; Sodium-Potassium-Exchanging ATPase	1989
[The efficacy of calcium antagonists in circulatory failure in elderly patients with hypertension]. Terapevticheskii arkhiv, 1989, Volume: 61, Issue:12 Topics: Aged; Calcium Channel Blockers; Digoxin; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Factors; Verapamil	1989
Acute hypotensive effect of calcium antagonists and endogenous digitalis-like immunoreactivity in human essential hypertension. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1986, Volume: 4, Issue:5 Topics: Adult; Aged; Blood Pressure; Blood Proteins; Calcium Channel Blockers; Cardenolides; Digoxin; Humans; Hypertension; Middle Aged; Nifedipine; Saponins; Sodium-Potassium-Exchanging ATPase	1986
Effects of mercaptans upon dihydropyridine binding sites on transverse tubules isolated from triads of rabbit skeletal muscle. Biochemical and biophysical research communications, 1985, Feb-28, Volume: 127, Issue:1 Topics: Animals; Digoxin; Dihydropyridines; Dithiothreitol; Glutathione; Glutathione Disulfide; Muscles; Nifedipine; Nitrendipine; Ouabain; Pyridines; Rabbits; Sulfhydryl Compounds	1985
[Quadratic analysis of left ventricular ejection phase volume using a M-mode echocardiogram, and the effects of beta-methyldigoxin, nifedipine, physical exercise and propranolol on new parameters]. Nihon Ika Daigaku zasshi, 1988, Volume: 55, Issue:6 Topics: Adult; Data Interpretation, Statistical; Digoxin; Echocardiography; Exercise; Female; Heart; Heart Diseases; Heart Ventricles; Humans; Male; Medigoxin; Middle Aged; Nifedipine; Propranolol; Stroke Volume	1988
Dose-dependence of the nifedipine/digoxin interaction? Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1986, Volume: 9 Topics: Adult; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Humans; Kinetics; Male; Nifedipine	1986
Nisoldipine, a new calcium antagonist, elevates plasma levels of digoxin. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1987, Volume: 11 Topics: Adult; Aged; Calcium Channel Blockers; Digoxin; Double-Blind Method; Drug Interactions; Female; Humans; Kinetics; Male; Middle Aged; Nifedipine; Nisoldipine; Random Allocation; Stroke Volume; Vasodilator Agents	1987
[Effect of corinfar on serum digoxin levels in patients with chronic cardiac insufficiency]. Kardiologiia, 1987, Volume: 27, Issue:7 Topics: Aged; Calcium Channel Blockers; Chronic Disease; Digoxin; Drug Therapy, Combination; Heart Failure; Humans; Middle Aged; Nifedipine	1987
Effects of unloading and positive inotropic interventions on left ventricular function in asymptomatic patients with chronic severe aortic insufficiency. Clinical cardiology, 1987, Volume: 10, Issue:12 Topics: Adult; Aortic Valve Insufficiency; Digoxin; Drug Therapy, Combination; Echocardiography; Female; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Contraction; Nifedipine	1987
Noninteraction of digoxin and nifedipine in cardiac patients. Journal of clinical pharmacology, 1986, Volume: 26, Issue:4 Topics: Adult; Coronary Disease; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Kinetics; Middle Aged; Nifedipine	1986
Non-interaction between nifedipine and digoxin. Danish medical bulletin, 1986, Volume: 33, Issue:2 Topics: Adult; Digoxin; Drug Interactions; Humans; Kidney; Male; Nifedipine; Osmolar Concentration	1986
Diltiazem-nifedipine-digoxin interaction. Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:12 Topics: Aged; Digoxin; Diltiazem; Drug Interactions; Humans; Male; Nifedipine	1986
[Dynamics of respiratory function and and bicycle ergometry in the treatment of patients with chronic circulatory failure]. Terapevticheskii arkhiv, 1986, Volume: 58, Issue:11 Topics: Adult; Calcium Channel Blockers; Digoxin; Drug Therapy, Combination; Exercise Test; Female; Forced Expiratory Flow Rates; Heart Failure; Humans; Male; Middle Aged; Nifedipine; Oxygen Consumption; Respiration; Vital Capacity	1986
Dose-dependence of the nifedipine-digoxin interaction? Clinical pharmacology and therapeutics, 1986, Volume: 39, Issue:1 Topics: Administration, Oral; Adult; Creatinine; Digoxin; Drug Interactions; Heart; Heart Rate; Humans; Kinetics; Male; Nifedipine	1986
Pharmacokinetic studies of nifedipine and digoxin co-administration. International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:1 Topics: Adult; Digoxin; Drug Interactions; Female; Humans; Kidney; Kinetics; Male; Metabolic Clearance Rate; Nifedipine	1986
Effects of nifedipine and diltiazem on plasma levels and renal excretion of beta-acetyldigoxin. Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:2 Topics: Acetyldigoxins; Aged; Benzazepines; Digoxin; Diltiazem; Drug Therapy, Combination; Female; Heart Failure; Humans; Kinetics; Male; Middle Aged; Nifedipine	1985
Interaction between digoxin and commonly coadministered drugs in children. Pediatrics, 1985, Volume: 75, Issue:6 Topics: Amiodarone; Child, Preschool; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Infant; Infant, Newborn; Nifedipine; Quinidine; Spironolactone; Verapamil	1985
Drug interactions with nitrendipine. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 7 Topics: Adrenergic beta-Antagonists; Adult; Calcium Channel Blockers; Chromatography, Gas; Cimetidine; Digitalis Glycosides; Digoxin; Drug Interactions; Female; Histamine H2 Antagonists; Humans; Kinetics; Male; Nifedipine; Nitrendipine; Ranitidine	1984
Digoxin-specific antibody fragments and a calcium antagonist for reversal of digoxin-induced mesenteric vasoconstriction. The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:10 Topics: Anesthesia; Animals; Blood Pressure; Calcium Channel Blockers; Cats; Digoxin; Female; Heart Rate; Immunoglobulin Fab Fragments; In Vitro Techniques; Male; Nifedipine; Splanchnic Circulation; Vasoconstriction	1983
Acute myocardial infarction in a thirty-six year old postpartum female. Angiology, 1984, Volume: 35, Issue:9 Topics: Adult; Aspirin; Digoxin; Electrocardiography; Ergonovine; Female; Heart Aneurysm; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nifedipine; Pregnancy; Puerperal Disorders	1984
Influence of atenolol and nifedipine on digoxin-induced inotropism in humans. British journal of clinical pharmacology, 1984, Volume: 18, Issue:6 Topics: Adult; Atenolol; Blood Pressure; Creatinine; Digoxin; Drug Interactions; Electrocardiography; Female; Heart Rate; Hemodynamics; Humans; Kidney Function Tests; Male; Myocardial Contraction; Nifedipine	1984
Interaction between digoxin and the calcium antagonists nicardipine and tiapamil. Clinical therapeutics, 1983, Volume: 5, Issue:6 Topics: Aged; Calcium Channel Blockers; Digoxin; Drug Interactions; Electrocardiography; Female; Humans; Male; Nicardipine; Nifedipine; Potassium; Propylamines; Tiapamil Hydrochloride; Time Factors	1983
[Increased digitalis-like activity in combined administration of calcium antagonists and digitalis preparations]. Giornale italiano di cardiologia, 1983, Volume: 13, Issue:9 Topics: Aged; Digoxin; Drug Interactions; Drug Therapy, Combination; Heart Failure; Humans; Medigoxin; Middle Aged; Nifedipine; Verapamil	1983
The effect of nifedipine on serum digoxin concentrations in patients. American heart journal, 1984, Volume: 107, Issue:4 Topics: Aged; Cardiovascular Diseases; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nifedipine	1984
Effects of calcium and its antagonists on the canine mesenteric circulation. Circulation research, 1981, Volume: 48, Issue:5 Topics: Animals; Blood Flow Velocity; Blood Pressure; Calcium; Calcium Chloride; Digoxin; Diltiazem; Dogs; Dose-Response Relationship, Drug; Egtazic Acid; Female; Male; Mesenteric Arteries; Muscle Contraction; Nifedipine; Norepinephrine; Salts; Splanchnic Circulation	1981
Acute hemodynamic effects of combined therapy with digoxin and nifedipine in patients with chronic heart failure. American heart journal, 1983, Volume: 106, Issue:2 Topics: Aged; Blood Pressure; Cardiac Output; Digoxin; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Mitral Valve Insufficiency; Nifedipine; Pyridines; Stroke Volume; Vascular Resistance	1983
Effect of nifedipine on digoxin kinetics in healthy subjects. Clinical pharmacology and therapeutics, 1982, Volume: 32, Issue:5 Topics: Adult; Digoxin; Drug Interactions; Female; Humans; Kinetics; Male; Middle Aged; Nifedipine; Pyridines	1982
[Interactions of digoxin and the nonsteroidal anti-inflammatory drugs, acetylsalicylic acid and nifedipine]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Dec-13, Volume: 37, Issue:49 Topics: Adult; Arthritis; Aspirin; Coronary Disease; Digoxin; Drug Interactions; Humans; Indomethacin; Male; Middle Aged; Neuritis; Nifedipine; Phenylbutazone; Pyridines	1982
Nifedipine in severe aortic regurgitation. The New England journal of medicine, 1995, May-11, Volume: 332, Issue:19 Topics: Aortic Valve Insufficiency; Digoxin; Humans; Nifedipine; Research Design	1995
Nifedipine in severe aortic regurgitation. The New England journal of medicine, 1995, May-11, Volume: 332, Issue:19 Topics: Aortic Valve Insufficiency; Digoxin; Humans; Nifedipine; Placebos	1995
Nifedipine in severe aortic regurgitation. The New England journal of medicine, 1995, May-11, Volume: 332, Issue:19 Topics: Aortic Valve Insufficiency; Digoxin; Humans; Nifedipine; Ventricular Function, Left	1995
Interaction between nifedipine and digoxin in rats. East African medical journal, 1995, Volume: 72, Issue:1 Topics: Animals; Digoxin; Drug Evaluation, Preclinical; Drug Interactions; Infusions, Intravenous; Male; Nifedipine; Rats	1995
Management of chronic aortic regurgitation. The New England journal of medicine, 1994, Sep-15, Volume: 331, Issue:11 Topics: Aortic Valve Insufficiency; Chronic Disease; Digoxin; Heart Valve Prosthesis; Humans; Nifedipine; Stroke Volume; Ventricular Function, Left	1994
[Comparative analysis of several treatment methods for severe congestive heart failure]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1993, Volume: 13, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Captopril; Digoxin; Drugs, Chinese Herbal; Female; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Nifedipine	1993
The influence of tocolytic therapy on serum digoxin-like immunoreactive substance concentration. Gynecologic and obstetric investigation, 1994, Volume: 37, Issue:1 Topics: Adult; Blood Proteins; Cardenolides; Digoxin; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Ritodrine; Saponins; Tocolysis	1994
Pharmacokinetic basis of nifedipine-digoxin interaction: a commentary. East African medical journal, 1995, Volume: 72, Issue:10 Topics: Animals; Digoxin; Drug Interactions; Humans; Metabolic Clearance Rate; Nifedipine; Rats; Tissue Distribution	1995
Re-evaluation of the mechanism and treatment of angina decubitus. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1996, Volume: 11, Issue:1 Topics: Adult; Aged; Angina Pectoris, Variant; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Digoxin; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Middle Aged; Nifedipine; Pulmonary Artery; Stroke Volume	1996
Arterial responses in vitro and plasma digoxin immunoreactivity after losartan and enalapril treatments in experimental hypertension. Pharmacology & toxicology, 2000, Volume: 86, Issue:1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Digoxin; Dihydropyridines; Enalapril; Heart; Hypertension; Losartan; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Organ Size; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium-Potassium-Exchanging ATPase; Tunica Media	2000
Inhibitory effects of CYP3A4 substrates and their metabolites on P-glycoprotein-mediated transport. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2001, Volume: 12, Issue:4 Topics: Amiodarone; Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Daunorubicin; Digoxin; Enzyme Inhibitors; GABA Modulators; Gonadal Steroid Hormones; Humans; LLC-PK1 Cells; Midazolam; Mixed Function Oxygenases; Nifedipine; Phthalazines; Swine; Testosterone	2001
Pharmacoepidemiologic detection of calcium channel blocker-induced change on digoxin clearance using multiple trough screen analysis. Biopharmaceutics & drug disposition, 2002, Volume: 23, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Calcium Channel Blockers; Creatinine; Digoxin; Diltiazem; Drug Interactions; Female; Heart Failure; Humans; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Models, Statistical; Nifedipine; Pharmacoepidemiology; Regression Analysis; Reproducibility of Results; Spironolactone; Verapamil	2002
Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2002, Volume: 16, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Digoxin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Gene Expression; Humans; Nifedipine; Paclitaxel; RNA, Messenger; Swine; Tritium; Tumor Cells, Cultured; Verapamil; Vinblastine	2002
Update on prescribing information for pantoprazole. American family physician, 2003, Mar-15, Volume: 67, Issue:6 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Clarithromycin; Digoxin; Drug Interactions; Esophagitis; Humans; Nifedipine; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Sulfoxides	2003
How inotropic drugs alter dynamic and static indices of cyclic myoplasmic [Ca2+] to contractility relationships in intact hearts. Journal of cardiovascular pharmacology, 2003, Volume: 42, Issue:4 Topics: Animals; Calcium; Digoxin; Dopamine; Guinea Pigs; Lidocaine; Muscle Contraction; Myocardial Contraction; Myocardium; Nifedipine; Signal Processing, Computer-Assisted; Ventricular Function; Ventricular Function, Left; Ventricular Pressure	2003
The electrophysiological effects of cardiac glycosides in human iPSC-derived cardiomyocytes and in guinea pig isolated hearts. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 27, Issue:5 Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cardiac Glycosides; Cell Differentiation; Cells, Cultured; Digoxin; Dose-Response Relationship, Drug; Electrocardiography; Guinea Pigs; Heart Rate; Hemodynamics; Humans; Microelectrodes; Myocardial Contraction; Myocytes, Cardiac; Nifedipine; Organ Culture Techniques; Ouabain; Pluripotent Stem Cells	2011
Activation of c-SRC underlies the differential effects of ouabain and digoxin on Ca(2+) signaling in arterial smooth muscle cells. American journal of physiology. Cell physiology, 2013, Feb-15, Volume: 304, Issue:4 Topics: Animals; Aorta; Calcium Channels; Calcium Signaling; Cardiotonic Agents; Cells, Cultured; Digoxin; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; Ouabain; Phosphorylation; Protein Processing, Post-Translational; Pyrimidines; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; src-Family Kinases; TRPC Cation Channels	2013