Compounds > nifedipine

nifedipine and digitoxin

nifedipine has been researched along with digitoxin in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's0 (0.00)18.2507
2000's4 (26.67)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Kuhlmann, J2
Moe, BH1
Frank, KH; Kuhlmann, J; Marcin, S1
Endou, K; Sato, T; Yamamoto, H1
Agostoni, PG; De Cesare, N; Doria, E; Guazzi, MD; Polese, A; Tamborini, G1
Weser, C1

Trials

3 trial(s) available for nifedipine and digitoxin

ArticleYear
Effects of verapamil, diltiazem, and nifedipine on plasma levels and renal excretion of digitoxin.
    Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:6

    Topics: Aged; Benzazepines; Clinical Trials as Topic; Digitoxin; Diltiazem; Drug Interactions; Drug Therapy, Combination; Female; Heart Diseases; Humans; Kidney; Kidney Diseases; Kinetics; Liver Diseases; Male; Middle Aged; Nifedipine; Radioimmunoassay; Verapamil

1985
[Pharmacokinetics and cardiac effect of beta-acetyldigoxin and digitoxin in combination therapy with nifedipine].
    Klinische Wochenschrift, 1984, May-15, Volume: 62, Issue:10

    Topics: Acetyldigitoxins; Aged; Digitoxin; Drug Therapy, Combination; Electrocardiography; Female; Heart Conduction System; Heart Failure; Heart Rate; Humans; Male; Metabolic Clearance Rate; Middle Aged; Nifedipine

1984
Afterload reduction: a comparison of captopril and nifedipine in dilated cardiomyopathy.
    British heart journal, 1986, Volume: 55, Issue:4

    Topics: Adult; Aged; Captopril; Cardiomyopathy, Dilated; Clinical Trials as Topic; Digitalis; Diuretics; Double-Blind Method; Drug Therapy, Combination; Echocardiography; Female; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Plants, Medicinal; Plants, Toxic

1986

Other Studies

12 other study(ies) available for nifedipine and digitoxin

ArticleYear
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of quinidine, verapamil and nifedipine on the pharmacokinetics and pharmacodynamics of digitoxin during steady state conditions.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:5

    Topics: Digitoxin; Drug Interactions; Electrocardiography; Heart; Humans; Kinetics; Nifedipine; Prospective Studies; Quinidine; Verapamil

1987
On the therapeutic mechanism of Mg2+ in digitoxic arrhythmias and the role of cardiac glycosides in Mg depletion.
    Magnesium, 1984, Volume: 3, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Calcium; Cardiac Glycosides; Digitoxin; Dogs; Female; Heart; Magnesium; Magnesium Deficiency; Male; Nifedipine; Purkinje Fibers

1984
Comparison of the effects of calcium channel blockers and antiarrhythmic drugs on digitalis-induced oscillatory afterpotentials on canine Purkinje fiber.
    Japanese heart journal, 1987, Volume: 28, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Digitalis; Diltiazem; Dogs; Electric Stimulation; Female; Heart Conduction System; Male; Mexiletine; Nicardipine; Nifedipine; Nitrendipine; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Purkinje Fibers; Verapamil

1987
[Treatment of angina pectoris with special reference to beta-blockers].
    Zeitschrift fur arztliche Fortbildung, 1982, Mar-15, Volume: 76, Issue:6

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Anticoagulants; Calcium Channel Blockers; Diagnosis, Differential; Digitalis; Drug Therapy, Combination; Humans; Nifedipine; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Plants, Medicinal; Plants, Toxic; Propanolamines; Propranolol; Verapamil

1982