nifedipine and diazepam

nifedipine has been researched along with diazepam in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (15.87)	18.7374
1990's	17 (26.98)	18.2507
2000's	22 (34.92)	29.6817
2010's	14 (22.22)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Antkiewicz-Michaluk, L; Marona, H; Pekala, E; Szneler, E; Walczak, M	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Bharathi, K; Prasad, KV; Prasanthi, G	2
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Beaumont, K; Di, L; Maurer, TS; Smith, DA	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Biondi, PA; Dolfini, E; Reschiotto, C; Secchi, C; Testa, R	1
Anan'ev, EA; Grek, OR; Kolpakov, MA; Sharapov, VI	1
Baba, A; Matsuda, T; Shimizu, I	1
Avakian, SD; de Paula, RS; Mansur, Ade P; Pileggi, F; Ramires, JA	1
Crichlow, EC; Mawby, DI; Meric, SM; Papich, MG	1
Dadkar, VN; Dhar, HL; Jaguste, VS	1
Geras-Raaka, E; Gershengorn, MC; Thaw, CN	1
Bender, AS; Hertz, L	1
Schwartzkroin, PA; Taube, JS	1
Chan, KH; Hseu, SS; Lee, TY; Lui, PW	1
Kataoka, Y; Kumakura, K; Ohara-Imaizumi, M; Ueki, S	1
Brown, T; Fogel, R; Gaginella, T; Marshall, D; Michelson, G; Senler, T	1
Mendelson, WB	1
Luu, MD; Martin, JV; Mendelson, WB; Paul, SM; Skolnic, P; Wagner, R	1
Banditt, P; Martens, J; Meyer, FP	1
Abrosimov, IIu; Karpova, MN; Kryzhanovskiĭ, GN	1
Bliesath, H; Hartmann, M; Huber, R; Radtke, HW; Steinijans, VW; Wurst, W; Zech, K	1
Misawa, M; Mizoguchi, H; Suzuki, T; Yoshiike, M	1
Motokawa, K; Naito, H; Ohashi, N; Sato, S; Takahashi, H	1
Albertson, TE; Derlet, RW; Tseng, CC	1
Awano, H; Misawa, M; Mizoguchi, H; Motegi, H; Suzuki, T	1
Code, WE; Hertz, L; Zhao, Z	1
Grek, OR; Sharapov, VI	1
Bardou, LG; Berthou, F; Dréano, Y; Iribarne, C; Ménez, JF	1
Garibova, TL; Kraĭneva, VA; Val'dman, EA; Voronina, TA	1
Mason, SR; Read, MA; Reilly, PE	1
Fowler, SM; Friedberg, T; Pritchard, MP; Riley, RJ; Sutcliffe, MJ; Wolf, CR	1
Grant, KA; Green-Jordan, K	1
Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA	1
Andersson, TB; Bredberg, E; Eriksson, UG; Eriksson-Lepkowska, M; Frison, L; Johansson, S; Larsson, M; Thuresson, A	1
Boni, C; El Ganouni, S; Hakkou, F; Hamon, M; Hanoun, N; Tazi, A	1
Hiroshi, N; Katoh, H; Okada, Y; Sakamoto, T; Shima, K; Tuzuki, N; Yanagawa, Y	1
Abbate, M; Ferlazzo, E; Granata, F; Mazzù, I; Musolino, R; Narbone, MC	1
Chou, D; Duley, L; Henderson-Smart, DJ	1
Adongo, DW; Mante, PK; Woode, E	1
Coboeken, K; Dallmann, A; Eissing, T; Hempel, G; Ince, I	1

Reviews

3 review(s) available for nifedipine and diazepam

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Lack of pantoprazole drug interactions in man. International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:8 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin	1994
Magnesium sulphate versus phenytoin for eclampsia. The Cochrane database of systematic reviews, 2010, Oct-06, Issue:10 Topics: Anticonvulsants; Clonazepam; Diazepam; Drug Combinations; Eclampsia; Female; Humans; Magnesium Sulfate; Nifedipine; Phenytoin; Pregnancy; Randomized Controlled Trials as Topic	2010

Trials

6 trial(s) available for nifedipine and diazepam

Article	Year
[Comparison of the effects of diazepam, nifedipine, propranolol and a combination of nifedipine and propranolol, by sublingual administration, in patients with hypertensive crisis]. Arquivos brasileiros de cardiologia, 1991, Volume: 57, Issue:4 Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Diazepam; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Propranolol; Risk Factors	1991
Effects of verapamil and nifedipine on psychomotor performance in human subjects. The Journal of the Association of Physicians of India, 1991, Volume: 39, Issue:6 Topics: Adult; Blood Pressure; Diazepam; Drug Evaluation; Female; Heart Rate; Higher Nervous Activity; Humans; Male; Nifedipine; Psychomotor Performance; Verapamil	1991
Midazolam as an induction agent for thoracotomy in comparison with diazepam with or without nifedipine. Ma zui xue za zhi = Anaesthesiologica Sinica, 1988, Volume: 26, Issue:2 Topics: Adult; Aged; Anesthetics; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Midazolam; Middle Aged; Nifedipine; Preanesthetic Medication; Random Allocation; Thoracotomy	1988
Determination of nifedipine in human serum by gas chromatography-mass spectrometry: validation of the method and its use in bioavailability studies. Journal of chromatography. B, Biomedical applications, 1994, Oct-14, Volume: 660, Issue:2 Topics: Biological Availability; Diazepam; Gas Chromatography-Mass Spectrometry; Humans; Light; Nifedipine; Quality Control	1994
Lack of pantoprazole drug interactions in man. International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:8 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin	1994
Ximelagatran, an oral direct thrombin inhibitor, has a low potential for cytochrome P450-mediated drug-drug interactions. Clinical pharmacokinetics, 2003, Volume: 42, Issue:8 Topics: Administration, Oral; Adult; Aged; Amidines; Anticoagulants; Area Under Curve; Azetidines; Benzylamines; Cross-Over Studies; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Diclofenac; Drug Interactions; Glycine; Humans; In Vitro Techniques; Infusions, Intravenous; Microsomes, Liver; Middle Aged; Nifedipine; Nordazepam; Prodrugs; Thrombin	2003

Other Studies

55 other study(ies) available for nifedipine and diazepam

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogPoct: a tool for lipophilicity determination in drug discovery. Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Anticonvulsant activity of some xanthone derivatives. Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Mice; Molecular Structure; Pentylenetetrazole; Rats; Seizures; Xanthones	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
Design, synthesis and evaluation of dialkyl 4-(benzo[d][1,3]dioxol-6-yl)-1,4-dihydro-2,6-dimethyl-1-substituted pyridine-3,5-dicarboxylates as potential anticonvulsants and their molecular properties prediction. European journal of medicinal chemistry, 2013, Volume: 66 Topics: Absorption; Analgesics; Animals; Anticonvulsants; Antioxidants; Chemistry Techniques, Synthetic; Drug Design; Male; Mice; Pyridines; Rats	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Synthesis, anticonvulsant activity and molecular properties prediction of dialkyl 1-(di(ethoxycarbonyl)methyl)-2,6-dimethyl-4-substituted-1,4-dihydropyridine-3,5-dicarboxylates. European journal of medicinal chemistry, 2014, Feb-12, Volume: 73 Topics: Administration, Oral; Animals; Anticonvulsants; Dihydropyridines; Drug Design; Male; Mice; Molecular Structure; Rats; Rats, Wistar; Seizures; Structure-Activity Relationship; Toxicity Tests, Acute	2014
Volume of Distribution in Drug Design. Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15 Topics: Drug Design; Half-Life; Pharmacokinetics	2015
GLC determination of nifedipine, a light sensitive drug, in plasma. Il Farmaco; edizione pratica, 1979, Volume: 34, Issue:11 Topics: Animals; Chromatography, Gas; Diazepam; Light; Male; Nifedipine; Pyridines; Rats; Trifluperidol; Ultraviolet Rays	1979
[Pharmacokinetics of antipyrine, nifedipine and diazepam in experimental myocardial infarct]. Biulleten' eksperimental'noi biologii i meditsiny, 1992, Volume: 113, Issue:4 Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Diazepam; Hydroxylation; Male; Microsomes, Liver; Myocardial Infarction; Nifedipine; Rats; Rats, Wistar; Time Factors	1992
Na+ influx-induced decrease of (Na+ + K+)-ATPase activity in rat brain slices: role of Ca2+. European journal of pharmacology, 1991, Nov-12, Volume: 204, Issue:3 Topics: Amiloride; Animals; Bepridil; Brain; Calcium; Calcium Channel Blockers; Cell Membrane; Chelating Agents; Diazepam; Egtazic Acid; In Vitro Techniques; Kinetics; Male; Monensin; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Quinacrine; Rats; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil; Veratrine	1991
Pharmacological relaxation of the urethra in male cats: a study of the effects of phenoxybenzamine, diazepam, nifedipine and xylazine. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1991, Volume: 55, Issue:1 Topics: Administration, Oral; Animals; Cats; Diazepam; Injections, Intravenous; Male; Muscle Relaxation; Muscle, Smooth; Muscles; Nifedipine; Phenoxybenzamine; Pressure; Random Allocation; Restraint, Physical; Urethra; Urinary Catheterization; Xylazine	1991
Benzodiazepines modulate voltage-sensitive calcium channels in GH3 pituitary cells at sites distinct from thyrotropin-releasing hormone receptors. Endocrinology, 1988, Volume: 123, Issue:1 Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Calcium; Cell Line; Chlordiazepoxide; Diazepam; Diltiazem; Ion Channels; Kinetics; Nifedipine; Pituitary Neoplasms; Potassium; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Thyrotropin-Releasing Hormone	1988
Pharmacological evidence that the non-neuronal diazepam binding site in primary cultures of glial cells is associated with a calcium channel. European journal of pharmacology, 1985, Apr-02, Volume: 110, Issue:2 Topics: Anti-Anxiety Agents; Benzodiazepinones; Binding, Competitive; Calcium Channel Blockers; Cells, Cultured; Convulsants; Diazepam; Humans; Ion Channels; Neuroglia; Nifedipine; Nitrendipine; Receptors, GABA-A	1985
Ineffectiveness of organic calcium channel blockers in antagonizing long-term potentiation. Brain research, 1986, Aug-06, Volume: 379, Issue:2 Topics: Action Potentials; Animals; Calcium Channel Blockers; Cinnarizine; Diazepam; Flunarizine; Guinea Pigs; Hippocampus; Neurons; Nifedipine; Nitrendipine; Reaction Time; Synaptic Transmission; Verapamil	1986
Stimulatory action of gamma-aminobutyric acid on catecholamine secretion from bovine adrenal chromaffin cells measured by a real-time monitoring system. Journal of neurochemistry, 1988, Volume: 50, Issue:6 Topics: Adrenal Glands; Animals; Catecholamines; Cattle; Chromaffin System; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Magnesium; Nifedipine	1988
Central administration of benzodiazepines alters water absorption by the rat ileum in vivo. Gastroenterology, 1987, Volume: 93, Issue:2 Topics: Animals; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; Ileum; Injections, Intraventricular; Intestinal Absorption; Lorazepam; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Water	1987
The benzodiazepine receptor and sleep. Psychiatric developments, 1984,Autumn, Volume: 2, Issue:3 Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Calcium; Carbolines; Diazepam; Flumazenil; Flurazepam; Humans; Motor Activity; Nifedipine; Phenobarbital; Pyrazoles; Rats; Receptors, GABA-A; Sleep; Synaptosomes	1984
Diazepam-stimulated increases in the synaptosomal uptake of 45Ca2+: reversal by dihydropyridine calcium channel antagonists. European journal of pharmacology, 1984, Sep-03, Volume: 104, Issue:1-2 Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Chloride; Calcium Radioisotopes; Cerebral Cortex; Diazepam; Dihydropyridines; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Synaptosomes	1984
[Anticonvulsant and neurotoxic effects of various combinations of phenobarbital, diazepam, sodium valproate, and 1,4-dihydropyridine ryodipine]. Biulleten' eksperimental'noi biologii i meditsiny, 1994, Volume: 118, Issue:7 Topics: Animals; Anticonvulsants; Diazepam; Drug Combinations; Drug Synergism; Mice; Nervous System; Nifedipine; Phenobarbital; Valproic Acid	1994
Effects of Ca2+ channel blockers on physical dependence on diazepam in mice. Life sciences, 1993, Volume: 53, Issue:22 Topics: Animals; Brain; Calcium Channel Blockers; Carbolines; Diazepam; Diltiazem; Drug Interactions; Flunarizine; Male; Mice; Mice, Inbred ICR; Nifedipine; Receptors, GABA-A; Seizures; Substance-Related Disorders	1993
Poisoning caused by the combined ingestion of nifedipine and metoprolol. Journal of toxicology. Clinical toxicology, 1993, Volume: 31, Issue:4 Topics: Administration, Oral; Adult; Calcium Chloride; Diazepam; Drug Combinations; Gastric Lavage; Humans; Male; Methylprednisolone; Metoprolol; Nifedipine; Tranquilizing Agents	1993
Acute cocaine toxicity: the effect of agents in non-seizure-induced death. Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:1 Topics: Animals; Anticonvulsants; Cocaine; Diazepam; Electrodes, Implanted; Electroencephalography; Male; Nifedipine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Respiratory Tract Diseases; Seizures	1993
Effects of nifedipine on physical dependence on barbital or diazepam in rats. The Journal of toxicological sciences, 1995, Volume: 20, Issue:4 Topics: Analysis of Variance; Animals; Barbital; Body Weight; Calcium Channel Blockers; Calcium Channels; Diazepam; Drug Synergism; Male; Motor Activity; Nifedipine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders	1995
Effects of benzodiazepines on potassium-induced increase in free cytosolic calcium concentration in astrocytes: interactions with nifedipine and the peripheral-type benzodiazepine antagonist PK 11195. Canadian journal of physiology and pharmacology, 1996, Volume: 74, Issue:3 Topics: Animals; Anti-Anxiety Agents; Astrocytes; Calcium; Calcium Channel Blockers; Cytosol; Diazepam; Drug Interactions; Isoquinolines; Membrane Potentials; Mice; Mice, Inbred Strains; Midazolam; Nifedipine; Potassium	1996
[Activity of liver monooxygenase system in rats with low and high resistance to hypoxia]. Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 122, Issue:9 Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Cytochromes b5; Diazepam; Hypoxia; Male; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Rats; Rats, Wistar; Species Specificity	1996
Interaction of methadone with substrates of human hepatic cytochrome P450 3A4. Toxicology, 1997, Feb-14, Volume: 117, Issue:1 Topics: Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Diazepam; Fluvoxamine; Humans; Methadone; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Rifampin	1997
[Effect of calcium channel blocker nifedipine on anxiety and seizure manifestations of abstinence syndrome in rats after withdrawal of long-term diazepam administration]. Biulleten' eksperimental'noi biologii i meditsiny, 1998, Volume: 125, Issue:5 Topics: Adaptation, Physiological; Animals; Anti-Anxiety Agents; Anxiety; Calcium Channel Blockers; Calcium Channels; Convulsants; Diazepam; Kindling, Neurologic; Male; Nifedipine; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders	1998
Human, rat and crocodile liver microsomal monooxygenase activities measured using diazepam and nifedipine: effects of CYP3A inhibitors and relationship to immunochemically detected CYP3A apoprotein. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1999, Volume: 122, Issue:2 Topics: Alligators and Crocodiles; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Enzyme Inhibitors; Female; Humans; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nifedipine; Oxidoreductases, N-Demethylating; Rats; Rats, Wistar; Sex Characteristics; Species Specificity; Substrate Specificity; Troleandomycin	1999
Amino acid 305 determines catalytic center accessibility in CYP3A4. Biochemistry, 2000, Apr-18, Volume: 39, Issue:15 Topics: Alanine; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Binding Sites; Catalysis; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Econazole; Erythromycin; Humans; Imidazoles; Ketoconazole; Kinetics; Miconazole; Mixed Function Oxygenases; Multienzyme Complexes; Mutation; Nifedipine; Oxidoreductases, N-Demethylating; Substrate Specificity; Testosterone	2000
Modulation of the ethanol-like discriminative stimulus effects of diazepam and phencyclidine by L-type voltage-gated calcium-channel ligands in rats. Psychopharmacology, 2000, Volume: 149, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Central Nervous System Depressants; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Modulators; Isradipine; Ligands; Male; N-Methylaspartate; Nifedipine; Nimodipine; Phencyclidine; Rats; Rats, Long-Evans	2000
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR. The Journal of endocrinology, 2000, Volume: 167, Issue:3 Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil	2000
Prevention of diazepam withdrawal syndrome by nifedipine-behavioural and neurochemical studies. Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:2 Topics: Animals; Anti-Anxiety Agents; Base Sequence; Behavior, Animal; Calcium Channel Blockers; Diazepam; Dose-Response Relationship, Drug; Drinking; Hippocampus; Hydroxyindoleacetic Acid; Male; Nifedipine; Rats; Rats, Wistar; Receptors, Glucocorticoid; RNA, Messenger; Serotonin; Substance Withdrawal Syndrome	2004
Intubation without premedication may worsen outcome for unconsciousness patients with intracranial hemorrhage. The American journal of emergency medicine, 2005, Volume: 23, Issue:2 Topics: Analgesics, Opioid; Anesthetics, Local; Anti-Anxiety Agents; Diazepam; Emergency Medicine; Female; Fentanyl; Glasgow Outcome Scale; Humans; Intracranial Hemorrhages; Intubation, Intratracheal; Lidocaine; Male; Middle Aged; Nicardipine; Nifedipine; Outcome and Process Assessment, Health Care; Pentazocine; Premedication; Retrospective Studies; Unconsciousness; Vasodilator Agents	2005
PRES: posterior or potentially reversible encephalopathy syndrome? Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2006, Volume: 27, Issue:3 Topics: Adult; Anti-Inflammatory Agents; Anticonvulsants; Antihypertensive Agents; Brain; Brain Diseases; Clonidine; Dexamethasone; Diazepam; Diuretics, Osmotic; Eclampsia; Female; Humans; Magnesium Sulfate; Magnetic Resonance Imaging; Mannitol; Nifedipine; Pregnancy; Seizures	2006
Anticonvulsant effects of antiaris toxicaria aqueous extract: investigation using animal models of temporal lobe epilepsy. BMC research notes, 2017, Apr-26, Volume: 10, Issue:1 Topics: Animals; Antiaris; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Administration Schedule; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred ICR; Nifedipine; Pentylenetetrazole; Pilocarpine; Plant Extracts; Rats; Rats, Sprague-Dawley	2017
A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways. Clinical pharmacokinetics, 2018, Volume: 57, Issue:6 Topics: Caffeine; Cytochrome P-450 Enzyme System; Diazepam; Female; Granisetron; Humans; Metoprolol; Metronidazole; Midazolam; Models, Biological; Nifedipine; Ondansetron; Pharmaceutical Preparations; Pregnancy	2018