nifedipine and debrisoquin

nifedipine has been researched along with debrisoquin in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's4 (44.44)18.2507
2000's1 (11.11)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belas, F; Chaudhary, AK; Cvetkovic, M; Dempsey, PJ; Fromm, MF; Kim, RB; Leake, B; Roden, DM; Roden, MM; Wandel, C; Wilkinson, GR; Wood, AJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Kallio, J1
Hoffmann, A; Sigusch, H1
Henschel, L; Hoffmann, A; Sigusch, H1
Beerahee, M; Beevers, DG; Jack, DB; Kendall, MJ; Wilkins, MR1
Henderson, CJ; McLaughlin, LA; Scheer, N; Stanley, LA; Wolf, CR1

Reviews

1 review(s) available for nifedipine and debrisoquin

ArticleYear
[Heritable polymorphisms in oxidative drug metabolism].
    Duodecim; laaketieteellinen aikakauskirja, 1990, Volume: 106, Issue:5

    Topics: Animals; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; In Vitro Techniques; Mephenytoin; Nifedipine; Oxidation-Reduction; Pharmaceutical Preparations; Phenacetin; Polymorphism, Genetic; Rats

1990

Other Studies

8 other study(ies) available for nifedipine and debrisoquin

ArticleYear
Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.
    Pharmaceutical research, 1999, Volume: 16, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Male; Mice; Oxidoreductases, N-Demethylating; Pharmacokinetics; Substrate Specificity

1999
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Verapamil but not nifedipine influences the metabolic ratio of debrisoquine hydroxylation.
    Die Pharmazie, 1991, Volume: 46, Issue:12

    Topics: Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Hydroxylation; Male; Nifedipine; Verapamil

1991
[The effects of verapamil and nifedipine on the biotransformation of model substances and on the indocyanine green elimination].
    Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR, 1991, Volume: 51, Issue:1

    Topics: Adult; Biotransformation; Caffeine; Debrisoquin; Dipyrone; Humans; Indocyanine Green; Liver; Liver Circulation; Male; Nifedipine; Sulfamethazine; Verapamil

1991
Twelve hour (trough) plasma nifedipine concentrations during chronic treatment with nifedipine retard.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:4

    Topics: Adult; Aged; Debrisoquin; Delayed-Action Preparations; Female; Humans; Hydroxylation; Male; Middle Aged; Nifedipine

1987
Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivo.
    Molecular pharmacology, 2015, Volume: 87, Issue:4

    Topics: Animals; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochromes b5; Debrisoquin; Ethanolamines; Female; Humans; Male; Mice, Knockout; Microsomes, Liver; Nifedipine; Sex Factors; Triazolam

2015