nifedipine and darodipine

nifedipine has been researched along with darodipine in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	49 (71.01)	18.7374
1990's	20 (28.99)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
de Ree, MM; Gahwiler, BH; Knot, HJ; Ruegg, UT	1
Colombo, G; Fadda, F; Garau, B; Gessa, GL	1
Hall, PF; Kawamura, M; Yanagibashi, K	1
Atkinson, J; Devissaguet, JP; Guerret, M; Hoffman, M; Hubert, B; Maincent, P	1
Doyle, VM; Hof, RP; Rüegg, UT; Zuber, JF	1
Hof, A; Hof, RP; Kalkman, HO	1
Creba, JA; Karobath, M	1
Holck, M; Osterrieder, W	1
Brown, DA; Gähwiler, BH	1
Archer, DP; Pappius, HM	1
Berg, C; DiFrancesco, GF; Gittos, M; Mir, AK; Petty, MA; Spedding, M	1
Gerthoffer, WT; Shafer, PG; Taylor, S	1
Bagwell, EE; Hungerford, RT; Lindenmayer, GE; Serafino, R	1
Chaumet-Riffaud, P; Lemaire, M; Pinquier, JL; Tillement, JP; Urien, S	1
Chaumet-Riffaud, P; Pinquier, JL; Tillement, JP; Urien, S	1
Cooper, SM; Wilson, C	1
Hof, RP	5
Barnett, HJ; Bogousslavsky, J; Carruthers, SG; Hachinski, VC; Oczkowski, WJ	1
Andersen, A; Paulson, OB; Vorstrup, S	1
Krikler, DM	1
Al-Mahmood, HA; el-Khatim, MS; Gumaa, KA; Thulesius, O	1
Handley, DA; Melden, MK; Saunders, RN; Van Valen, RG	1
Chaumet-Riffaud, P; Kiechel, JR; Paquette, B; Pinquier, JL; Tillement, JP; Urien, S	1
Barrès, C; Cerutti, C; Morin, B; Sassard, J	1
Jie, K; Timmermans, PB; van Brummelen, P; van Zwieten, PA; Vermey, P	1
Chrysant, C; Chrysant, SG; Hitchcock, A; Trus, J	1
de Buitleir, M; Krikler, DM; Krikler, S	2
Raeburn, D; Roberts, JA; Rodger, IW; Thomson, NC	1
Andersen, A; Blegvad, N; Paulson, OB; Vorstrup, S	1
Ben-Dov, I; Hansen, JE; Olive, SR; Sue, DY; Wasserman, K	1
Hof, A; Hof, RP	1
Grebb, JA	1
Carey, B; Ginsburg, R; Zera, P	1
Ben-Dov, I; Hansen, JE; Sue, DY; Wasserman, K	1
Bowles, MJ; Khurmi, NS; O'Hara, MJ; Raftery, EB	1
Karobath, M; Supavilai, P	1
Hess, T; Riesen, W; Salzmann, R; Scholtysik, G	1
de Jonge, A; Kalkman, HO; Mathy, MJ; Thoolen, MJ; Timmermans, PB; van Meel, JC; van Zwieten, PA; Wilffert, B	1
Dollery, CT; Ennis, M; Ind, PW; Pearce, FL	1
Hof, A; Hof, RP; Loutzenhiser, R; Rüegg, UT	1
Cortés, R; Karobath, M; Palacios, JM; Supavilai, P	1
De Zoeten, K; Timmermans, PB; Van Meel, JC; Van Zwieten, PA; Wilffert, B	1
Delgado, C; Diez, J; Tamargo, J; Tejerina, MT	1
Nievelstein, HM; Smits, JF; Struyker-Boudier, HA; van Essen, H	1
Advenier, C; Cerrina, J; Duroux, P; Floch, A; Renier, A	1
Wiernsperger, N	1
Hof, RP; Vuorela, HJ	1
Brown, BL; Mac Neil, S; Tomlinson, S; Walker, SW	1
Dall'Olio, R; Gaggi, R; Gianni, AM; Roncada, P	1
Amenta, F; Ferrante, F; Mancini, M; Sabbatini, M; Vega, JA; Zaccheo, D	1
Amenta, F; Cavallotti, D; Del Valle, M; Mancini, M; Naves, FJ; Vega, JA; Zeng, YC	1
Amenta, F; Mancini, M; Naves, FJ; Vega, JA; Zaccheo, D	1
Agabio, R; Colombo, G; Fadda, F; Gessa, GL; Lobina, C; Melis, F; Reali, R	1
Amenta, F; Del Valle, ME; Sabbatini, M; Vega, JA	1
Brée, F; Carrupt, PA; Giroud, Y; Testa, B; Tillement, JP; Tsai, RS; Urien, S	1
Amenta, F; Ferrante, F; Ricci, A; Rossodivita, I	1
Busico, S; Di Bon, G; Ferrari, A; Riela, S; Sannita, WG	1
Rüegg, UT; Skutella, M	1
Brauns, T; Glossmann, H; Haugland, RP; Kimball, SD; Prinz, H; Striessnig, J	1
Dailly, E; Jolliet, P; Simon, N; Tillement, JP; Urien, S	1
D'Allolio, R; Gaggi, R; Roncada, P; Santangelo, M	1
Gauguier, D; Lathrop, GM; Samani, NJ; Sassard, J; Thompson, JR; Vincent, M	1
Barbieri, M; Cerbai, E; Matucci, R; Mugelli, A; Ottaviani, MF	1
Garbarino, S; Gesino, D; Massimilla, S; Ogliastro, C; Sannita, WG	1

Reviews

2 review(s) available for nifedipine and darodipine

Article	Year
PY 108-068: a calcium antagonist with an unusual pattern of cardiovascular activity. General pharmacology, 1985, Volume: 16, Issue:1 Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular System; Cats; Chemoreceptor Cells; Coronary Circulation; Dogs; Drug Interactions; Electrophysiology; Guinea Pigs; Humans; In Vitro Techniques; Ion Channels; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Rabbits; Rats; Regional Blood Flow; Sinoatrial Node	1985
Calcium antagonists for chronic stable angina pectoris. The American journal of cardiology, 1987, Jan-30, Volume: 59, Issue:3 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Drug Therapy, Combination; Humans; Myocardial Contraction; Nifedipine	1987

Article

Year

PY 108-068: a calcium antagonist with an unusual pattern of cardiovascular activity.

General pharmacology, 1985, Volume: 16, Issue:1

Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular System; Cats; Chemoreceptor Cells; Coronary Circulation; Dogs; Drug Interactions; Electrophysiology; Guinea Pigs; Humans; In Vitro Techniques; Ion Channels; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Rabbits; Rats; Regional Blood Flow; Sinoatrial Node

1985

Calcium antagonists for chronic stable angina pectoris.

The American journal of cardiology, 1987, Jan-30, Volume: 59, Issue:3

Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Drug Therapy, Combination; Humans; Myocardial Contraction; Nifedipine

1987

Trials

10 trial(s) available for nifedipine and darodipine

Article	Year
A double-blind, randomized trial of PY108-068 in acute ischemic cerebral infarction. Stroke, 1989, Volume: 20, Issue:5 Topics: Acute Disease; Aged; Aged, 80 and over; Brain Ischemia; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nifedipine; Pilot Projects; Random Allocation; Severity of Illness Index	1989
Influence of calcium entry blockade on alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in the forearm of hypertensive patients. European journal of clinical pharmacology, 1987, Volume: 32, Issue:2 Topics: Adult; Azepines; Calcium Channel Blockers; Female; Forearm; Hemodynamics; Humans; Hypertension; Isradipine; Male; Methoxamine; Middle Aged; Nifedipine; Oxadiazoles; Receptors, Adrenergic, alpha; Regional Blood Flow; Vascular Resistance; Vasoconstriction	1987
Monotherapy of hypertension with darodipine: a new calcium-channel blocker. Clinical cardiology, 1988, Volume: 11, Issue:7 Topics: Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation	1988
Usefulness of PY 108-068, a new calcium channel blocker, for angina pectoris. The American journal of cardiology, 1986, Jan-01, Volume: 57, Issue:1 Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Electrocardiography; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Monitoring, Physiologic; Nifedipine; Nitroglycerin; Random Allocation; Tablets	1986
Comparison of PY 108-068, a new calcium antagonist, with nifedipine in exercise-induced asthma. Chest, 1986, Volume: 90, Issue:2 Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchi; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Nifedipine; Pulmonary Ventilation; Random Allocation; Spirometry; Time Factors	1986
PY 108-068--acute effects of a single oral dose in chronic stable angina. European journal of clinical pharmacology, 1986, Volume: 30, Issue:2 Topics: Administration, Oral; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Chronic Disease; Coronary Disease; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Nifedipine	1986
Bronchodilatation and attenuation of exercise-induced bronchospasm by PY 108-068, a new calcium antagonist. The American review of respiratory disease, 1986, Volume: 133, Issue:1 Topics: Adult; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Calcium Channel Blockers; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Nifedipine; Pulmonary Ventilation; Time Factors; Vital Capacity	1986
Objective evaluation of PY-108-068, a new calcium channel inhibitor for the treatment of chronic stable angina pectoris. European heart journal, 1985, Volume: 6, Issue:8 Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Nifedipine	1985
Pharmacokinetics and electroencephalographic effects of darodipine 50-200 mg modified release (MR) acute oral administration: dose-finding study in healthy volunteers. International journal of clinical pharmacology research, 1993, Volume: 13, Issue:5 Topics: Administration, Oral; Adult; Blood Pressure; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Follow-Up Studies; Heart Rate; Humans; Male; Nifedipine	1993
Plasma concentration and CNS effects of Ca antagonists darodipine and nimodipine after single-dose oral administration to healthy volunteers. Neuropsychobiology, 1999, Volume: 40, Issue:3 Topics: Adult; Blood Pressure; Calcium Channel Blockers; Central Nervous System; Electroencephalography; Heart Rate; Humans; Male; Neuropsychological Tests; Nifedipine; Nimodipine	1999

Other Studies

57 other study(ies) available for nifedipine and darodipine

Article	Year
Action of vasoconstrictor hormones and calcium entry modulators on electrical activity and intracellular calcium of smooth muscle cells. Advances in experimental medicine and biology, 1992, Volume: 311 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Barium; Barium Compounds; Cadmium; Cadmium Chloride; Calcium Channel Blockers; Cell Line; Chlorides; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Vasoconstrictor Agents; Vasopressins	1992
Isradipine and other calcium channel antagonists attenuate ethanol consumption in ethanol-preferring rats. Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:3 Topics: Alcohol Drinking; Animals; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Ethanol; Isradipine; Male; Nifedipine; Rats; Rats, Inbred Strains; Verapamil	1992
Voltage-dependent Ca2+ channels are involved in regulation of steroid synthesis by bovine but not rat fasciculata cells. Endocrinology, 1990, Volume: 127, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Bucladesine; Calcium; Calcium Channel Blockers; Calcium Channels; Cattle; Female; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Zona Fasciculata; Zona Reticularis	1990
The preparation and acute antihypertensive effects of a nanocapsular form of darodipine, a dihydropyridine calcium entry blocker. Pharmaceutical research, 1991, Volume: 8, Issue:6 Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Capsules; Hypertension, Renovascular; Male; Nifedipine; Rats; Rats, Inbred Strains; Suspensions	1991
A smooth muscle cell line suitable for the study of voltage sensitive calcium channels. Biochemical and biophysical research communications, 1985, Jul-16, Volume: 130, Issue:1 Topics: Animals; Biological Transport; Calcium; Calcium-Transporting ATPases; Cell Line; Ion Channels; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Potassium Chloride; Rats; Sodium-Potassium-Exchanging ATPase; Verapamil	1985
Modification of the vasoconstrictor effects of noradrenaline and serotonin by the selective calcium antagonist PY 108-068 in the peripheral circulation of anesthetized cats. Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 6 Topics: Animals; Cats; Drug Administration Schedule; Hemodynamics; Nifedipine; Norepinephrine; Regional Blood Flow; Serotonin Antagonists; Vasoconstriction	1985
The effect of dihydropyridine calcium agonists and antagonists on neuronal voltage sensitive calcium channels. Biochemical and biophysical research communications, 1986, Feb-13, Volume: 134, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Animals; Brain Chemistry; Calcium; Calcium Channel Blockers; Cell Line; Dihydropyridines; Electric Stimulation; Glioma; In Vitro Techniques; Ion Channels; Neuroblastoma; Neurons; Nifedipine; Potassium; Pyridines; Rats; Synaptosomes; Verapamil	1986
Inhibition of myocardial Ca2+ channels by three dihydropyridines with different structural features: potential-dependent blockade by Ro 18-3981. British journal of pharmacology, 1987, Volume: 91, Issue:1 Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Female; Guinea Pigs; Heart; In Vitro Techniques; Ion Channels; Isradipine; Male; Membrane Potentials; Myocardial Contraction; Myocardium; Nifedipine; Oxadiazoles; Potassium; Pyridines	1987
Effects of dihydropyridines on calcium currents in CA3 pyramidal cells in slice cultures of rat hippocampus. Neuroscience, 1987, Volume: 20, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Cadmium; Calcium; Electric Conductivity; Hippocampus; In Vitro Techniques; Membrane Potentials; Nifedipine; Rats	1987
Effects of two dihydropyridine calcium channel blockers on cerebral metabolism and blood flow in traumatized rat brain. Neurochemical pathology, 1986, Volume: 5, Issue:2 Topics: Animals; Blood Glucose; Brain; Brain Injuries; Calcium; Calcium Channel Blockers; Cerebrovascular Circulation; Energy Metabolism; Freezing; Ion Channels; Male; Nifedipine; Nimodipine; Parietal Lobe; Rats; Rats, Inbred Strains	1986
MDL 72567, a dihydropyridine calcium-antagonist, that causes vasodilation and direct sinus bradycardia. Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:1 Topics: Animals; Bradycardia; Calcium Channel Blockers; Calcium Channels; Decerebrate State; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Guinea Pigs; Hypertension, Renal; Male; Nicotinic Acids; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Vasodilation	1987
Selectivity of phenytoin and dihydropyridine calcium channel blockers for relaxation of the basilar artery. Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Dinoprost; Dogs; Dose-Response Relationship, Drug; Nifedipine; Phenytoin; Potassium; Prostaglandins F; Serotonin; Vasoconstriction; Vasodilation	1987
Relationship between steady-state depression of calcium-dependent action potentials and competition for binding sites by nifedipine, nitrendipine, and PY 108-068. Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:6 Topics: Action Potentials; Animals; Binding, Competitive; Calcium; Dogs; Heart; In Vitro Techniques; Myocardium; Nifedipine; Nitrendipine; Purkinje Fibers	1987
Comparative binding of two closely related dihydropyridines (isradipine and darodipine) to serum proteins and erythrocytes. Pharmacology, 1988, Volume: 36, Issue:5 Topics: Binding, Competitive; Blood Proteins; Calcium Channel Blockers; Dihydropyridines; Erythrocytes; gamma-Globulins; Humans; Isradipine; Lipoproteins; Nifedipine; Pyridines	1988
Differences in the serum binding determinants of isradipine and darodipine--consequences for serum protein binding in various diseases. British journal of clinical pharmacology, 1989, Volume: 28, Issue:5 Topics: Adult; Blood Proteins; Calcium Channel Blockers; Fatty Acids, Nonesterified; Female; Humans; Hydrogen-Ion Concentration; Inflammation; Isradipine; Liver Diseases; Male; Middle Aged; Nifedipine; Orosomucoid; Protein Binding; Pyridines; Serum Albumin	1989
Effect of cromakalim on contractions in rabbit isolated renal artery in the presence and absence of extracellular Ca2+. British journal of pharmacology, 1989, Volume: 98, Issue:4 Topics: Animals; Benzopyrans; Caffeine; Calcium; Calcium Channel Blockers; Cromakalim; Guanidines; Guanylate Cyclase; Histamine; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Norepinephrine; Pinacidil; Pyrroles; Rabbits; Renal Artery; Vasodilator Agents	1989
CBF decreases after calcium antagonist treatment in acute ischemic stroke. Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1989, Volume: 30, Issue:7 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Circulation; Female; Humans; Male; Middle Aged; Nifedipine	1989
The effect of calcium-blockers nicardipine, darodipine, PN-200-110 and nifedipine on insulin release from isolated rat pancreatic islets. Acta physiologica Scandinavica, 1986, Volume: 126, Issue:2 Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isradipine; Male; Nicardipine; Nifedipine; Oxadiazoles; Rats; Rats, Inbred Strains	1986
Suppression of rat carotid lesion development by the calcium channel blocker PN 200-110. The American journal of pathology, 1986, Volume: 124, Issue:1 Topics: Angioplasty, Balloon; Animals; Arteriosclerosis; Blood Platelets; Blood Pressure; Carotid Arteries; Hypotension; Isradipine; Male; Muscle, Smooth, Vascular; Nifedipine; Oxadiazoles; Rats; Rats, Inbred Strains	1986
Effect of the binding of isradipine and darodipine to different plasma proteins on their transfer through the rat blood-brain barrier. Drug binding to lipoproteins does not limit the transfer of drug. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1 Topics: Animals; Biological Transport; Blood Proteins; Blood-Brain Barrier; Brain; Humans; Isradipine; Lipoproteins; Liver; Male; Nifedipine; Orosomucoid; Pyridines; Rats; Rats, Inbred Strains; Serum Albumin	1987
Cardiovascular effects of two new calcium antagonists, PY 108-068 and PN 200-110, in conscious spontaneously hypertensive rats. British journal of pharmacology, 1988, Volume: 93, Issue:1 Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Isradipine; Male; Nifedipine; Nitroglycerin; Oxadiazoles; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Reflex	1988
Agonist-induced contractile responses of human bronchial muscle in vitro: effects of Ca2+ removal, La3+ and PY108068. European journal of pharmacology, 1986, Feb-18, Volume: 121, Issue:2 Topics: Bronchi; Calcimycin; Calcium; Calcium Channel Blockers; Histamine; Humans; In Vitro Techniques; Lanthanum; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Chloride; SRS-A	1986
Calcium antagonist (PY 108-068) treatment may further decrease flow in ischemic areas in acute stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:2 Topics: Acute Disease; Adult; Aged; Brain; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Humans; Male; Middle Aged; Nifedipine; Time Factors; Tomography, Emission-Computed; Vasodilation	1986
Mutual inhibition and synergistic effects of ergotamine and the calcium antagonist darodipine. General pharmacology, 1986, Volume: 17, Issue:3 Topics: Animals; Calcium Channel Blockers; Cats; Drug Synergism; Ergotamine; Hemodynamics; Nifedipine; Organ Specificity; Regional Blood Flow; Vasoconstriction	1986
Nifedipine and flunarizine block amphetamine-induced behavioral stimulation in mice. Life sciences, 1986, Jun-30, Volume: 38, Issue:26 Topics: Animals; Calcium Channel Blockers; Cinnarizine; Dextroamphetamine; Dose-Response Relationship, Drug; Flunarizine; Mice; Motor Activity; Nifedipine	1986
Effect of calcium antagonist darodipine on the isolated human heart. European journal of pharmacology, 1986, Jun-17, Volume: 125, Issue:2 Topics: Calcium; Calcium Channel Blockers; Carbachol; Coronary Vessels; Heart; Histamine; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Nifedipine; Potassium Chloride	1986
Vasopressin induced myocardial depression in neurally mediated and not due to impaired coronary blood flow. British journal of pharmacology, 1986, Volume: 87, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Coronary Circulation; Hemodynamics; Lypressin; Microspheres; Nifedipine; Rabbits; Reflex	1986
Modification of vasopressin- and angiotensin II- induced changes by calcium antagonists in the peripheral circulation of anaesthetized rabbits. British journal of pharmacology, 1985, Volume: 85, Issue:1 Topics: Anesthesia; Angiotensin II; Animals; Calcium Channel Blockers; Hemodynamics; Lypressin; Microspheres; Nifedipine; Rabbits; Regional Blood Flow; Vasoconstriction	1985
The interaction of [3H]PY 108-068 and of [3H]PN 200-110 with calcium channel binding sites in rat brain. Journal of neural transmission, 1984, Volume: 60, Issue:3-4 Topics: Animals; Brain; In Vitro Techniques; Ion Channels; Isradipine; Kinetics; Male; Membranes; Molecular Conformation; Nifedipine; Oxadiazoles; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1984
Digoxin-specific antibody fragments and a calcium antagonist for reversal of digoxin-induced mesenteric vasoconstriction. The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:10 Topics: Anesthesia; Animals; Blood Pressure; Calcium Channel Blockers; Cats; Digoxin; Female; Heart Rate; Immunoglobulin Fab Fragments; In Vitro Techniques; Male; Nifedipine; Splanchnic Circulation; Vasoconstriction	1983
Differential effect of calcium entry blockers on alpha 1-adrenoceptor-mediated vasoconstriction in vivo. Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 324, Issue:4 Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Calcium Channel Blockers; Catecholamines; Clonidine; Ethanolamines; Imidazoles; Imidazolines; Male; Methoxamine; Nifedipine; Phenylephrine; Rats; Rats, Inbred Strains; Vasoconstriction; Verapamil	1983
Calcium antagonists and histamine secretion from rat peritoneal mast cells. Agents and actions, 1983, Volume: 13, Issue:2-3 Topics: Animals; Ascitic Fluid; Calcium; Calcium Channel Blockers; Female; Histamine Release; In Vitro Techniques; Male; Mast Cells; Nifedipine; Rats; Rats, Inbred Strains; Verapamil	1983
Studies on the mechanism of action of the vasoconstrictive dihydropyridine, CGP 28392. European journal of pharmacology, 1984, Oct-15, Volume: 105, Issue:3-4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Nifedipine; Potassium Chloride; Pyridines; Rabbits; Vasoconstriction; Vasoconstrictor Agents	1984
Calcium antagonist binding sites in the rat brain: quantitative autoradiographic mapping using the 1,4-dihydropyridines [3H]PN 200-110 and [3H]PY 108-068. Journal of neural transmission, 1984, Volume: 60, Issue:3-4 Topics: Animals; Autoradiography; Binding Sites; Brain; Calcium Channel Blockers; Isradipine; Male; Nifedipine; Oxadiazoles; Rats; Rats, Inbred Strains	1984
The inhibitory effect of newer calcium antagonists (nimodipine and PY-108-068) on vasoconstriction in vivo mediated by postsynaptic alpha 2-adrenoceptors. Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 260, Issue:2 Topics: Animals; Azepines; Blood Pressure; Calcium Channel Blockers; Heart Rate; Male; Methoxamine; Nicotinic Acids; Nifedipine; Nimodipine; Norepinephrine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vasoconstriction	1982
Inotropic and electrophysiological effects of PY 108-068 on isolated cardiac preparations. Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 271, Issue:1 Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardial Contraction; Nifedipine; Papillary Muscles; Rats; Verapamil	1984
Calcium antagonists: systemic and regional haemodynamic effects in conscious spontaneously hypertensive rats (SHR). Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3 Topics: Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Hemodynamics; Male; Nifedipine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Reflex; Sinoatrial Node; Verapamil; Wakefulness	1984
Effects of five different organic calcium antagonists on guinea-pig isolated trachea. British journal of pharmacology, 1984, Volume: 82, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Bepridil; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicardipine; Nifedipine; Pyrrolidines; Trachea; Verapamil	1984
Focal epicerebral ischemia: post-ischemic tissue oxygenation with and without recirculation. Advances in experimental medicine and biology, 1984, Volume: 169 Topics: Animals; Aspirin; Cats; Cerebrovascular Circulation; Injections, Intravenous; Ischemic Attack, Transient; Nifedipine; Oxygen Consumption	1984
The calcium antagonists PY 108-068 and verapamil diminish the effects of angiotensin II: sites of interaction in the peripheral circulation of anaesthetized cats. British journal of pharmacology, 1984, Volume: 82, Issue:1 Topics: Anesthesia; Angiotensin II; Animals; Calcium Channel Blockers; Cardiac Output; Cats; Hemodynamics; Neural Conduction; Nifedipine; Regional Blood Flow; Vascular Resistance; Verapamil	1984
Calcium antagonist and the peripheral circulation: differences and similarities between PY 108-068, nicardipine, verapamil and diltiazem. British journal of pharmacology, 1983, Volume: 78, Issue:2 Topics: Animals; Calcium Channel Blockers; Cats; Diltiazem; Hemodynamics; Microspheres; Neural Conduction; Nicardipine; Nifedipine; Regional Blood Flow; Verapamil	1983
Assessing calcium antagonism on vascular smooth muscle: a comparison of three methods. Journal of pharmacological methods, 1983, Volume: 9, Issue:1 Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Potassium Chloride; Rabbits; Verapamil	1983
Evidence that calmodulin may be involved in phytohaemagglutinin-stimulated lymphocyte division. Bioscience reports, 1982, Volume: 2, Issue:11 Topics: Calcium-Binding Proteins; Calmodulin; DNA Replication; Humans; Lymphocyte Activation; Lymphocytes; Nifedipine; Phytohemagglutinins; Pyridines; Sulfonamides; Trifluoperazine; Vasodilator Agents	1982
Peculiar effects of isradipine and darodipine on the rat brain dopaminergic system. General pharmacology, 1995, Volume: 26, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium Channel Blockers; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Injections, Intraperitoneal; Isradipine; Male; Motor Activity; Nifedipine; Nimodipine; Parietal Lobe; Rats; Rats, Sprague-Dawley	1995
Effect of long-term treatment with the dihydropyridine-type calcium channel blocker darodipine (PY 108-068) on the cerebral capillary network in aged rats. Mechanisms of ageing and development, 1995, Jan-31, Volume: 78, Issue:1 Topics: Aging; Alkaline Phosphatase; Analysis of Variance; Animals; Calcium Channel Blockers; Capillaries; Cerebral Cortex; Cerebrovascular Circulation; Hippocampus; Male; Nifedipine; Random Allocation; Rats; Rats, Wistar	1995
Age-related changes in brain microanatomy: sensitivity to treatment with the dihydropyridine calcium channel blocker darodipine (PY 108-068). Brain research bulletin, 1995, Volume: 36, Issue:5 Topics: Aging; Alkaline Phosphatase; Animals; Brain; Calcium Channel Blockers; Lipofuscin; Male; Neurons; Nifedipine; Rats; Rats, Wistar; Tissue Distribution	1995
Effect of treatment with the dihydropyridine-type calcium antagonist darodipine (PY 108-068) on the expression of calbindin D-28K immunoreactivity in the cerebellar cortex of aged rats. Mechanisms of ageing and development, 1995, Jan-13, Volume: 77, Issue:3 Topics: Aging; Animals; Calbindins; Calcium Channel Blockers; Cerebellar Cortex; Immunohistochemistry; Male; Molecular Weight; Nerve Tissue Proteins; Nifedipine; Rats; Rats, Wistar; S100 Calcium Binding Protein G; Tissue Distribution	1995
Effects of the calcium channel antagonist darodipine on ethanol withdrawal in rats. Alcohol and alcoholism (Oxford, Oxfordshire), 1995, Volume: 30, Issue:1 Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Ethanol; Male; Nifedipine; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Substance Withdrawal Syndrome; Time Factors; Weight Loss	1995
Effect of treatment with the dihydropyridine-type calcium antagonist darodipine (PY 108-068) on the expression of neurofilament protein immunoreactivity in the cerebellar cortex of aged rats. Mechanisms of ageing and development, 1994, Volume: 75, Issue:2 Topics: Aging; Animals; Calcium Channel Blockers; Cerebellar Cortex; Immunohistochemistry; Male; Neurofilament Proteins; Nifedipine; Rats; Rats, Wistar	1994
Mechanism of ligand binding to alpha 1-acid glycoprotein (orosomucoid): correlated thermodynamic factors and molecular parameters of polarity. The Biochemical journal, 1995, Mar-01, Volume: 306 ( Pt 2) Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Hydrogen Bonding; Indoles; Isradipine; Ligands; Nifedipine; Orosomucoid; Progesterone; Propanolamines; Propranolol; Temperature; Thermodynamics; Warfarin	1995
Influence of treatment with the calcium channel blocker darodipine (PY 108-068) on the morphology of pial and coronary arteries in spontaneously hypertensive rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 1994, Volume: 16, Issue:3 Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cerebral Arteries; Coronary Vessels; Male; Nifedipine; Pia Mater; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1994
Increase of empty pool-activated Ca2+ influx using an intracellular Ca2+ chelating agent. Biochemical and biophysical research communications, 1996, Jan-26, Volume: 218, Issue:3 Topics: Animals; Arginine Vasopressin; Biological Transport; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Compartmentation; Cell Membrane; Cells, Cultured; Chelating Agents; Cytoplasm; Egtazic Acid; Enzyme Inhibitors; Imidazoles; Kinetics; Muscle, Smooth, Vascular; Nifedipine; Rats; Terpenes; Thapsigargin	1996
L-type calcium channels: binding domains for dihydropyridines and benzothiazepines are located in close proximity to each other. Biochemistry, 1997, Mar-25, Volume: 36, Issue:12 Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Fluorescent Dyes; Isomerism; Isradipine; Kinetics; Nicotinic Acids; Nifedipine; Nitrendipine; Oxadiazoles; Rabbits	1997
pH dependent binding of ligands to serum lipoproteins. Pharmaceutical research, 1997, Volume: 14, Issue:4 Topics: Hydrogen-Ion Concentration; Indoles; Lipoproteins; Nicardipine; Nifedipine; Protein Binding; Spectrum Analysis	1997
Interactions between darodipine or isradipine and the 5-HT1A receptor agonist 8-OHDPAT in rat brain. Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Interactions; Isradipine; Male; Nifedipine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists	1997
A pharmacogenetic approach to blood pressure in Lyon hypertensive rats. A chromosome 2 locus influences the response to a calcium antagonist. The Journal of clinical investigation, 1997, Oct-15, Volume: 100, Issue:8 Topics: Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Chromosome Mapping; Crosses, Genetic; Diastole; Disease Models, Animal; Female; Hypertension; Lod Score; Male; Microsatellite Repeats; Nifedipine; Phenotype; Quantitative Trait, Heritable; Rats; Renin-Angiotensin System; Sympathetic Nervous System; Systole	1997
Protective effect of darodipine, a calcium antagonist, on rat cardiomyocytes against oxygen radical-mediated injury. British journal of pharmacology, 1997, Volume: 122, Issue:7 Topics: Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Electrophysiology; Free Radicals; Heart; Male; Membrane Potentials; Myocardium; Nifedipine; Rats; Rats, Wistar; Reactive Oxygen Species	1997