nifedipine has been researched along with cyclosporine in 182 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 98 (53.85) | 18.2507 |
| 2000's | 54 (29.67) | 29.6817 |
| 2010's | 27 (14.84) | 24.3611 |
| 2020's | 3 (1.65) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dong, G; Liu, N; Sheng, C; Tu, J; Wang, Y | 1 |
| Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF | 1 |
| Nowotny, P; Vierhapper, H; Wagner, OF; Waldhäusl, W | 1 |
| Berland, Y; Chauvet-Monges, AM; Crevat, A; Dussol, B; Elsen, R; Salducci, MD | 1 |
| Alcazar, JM; Andres, A; Montoyo, C; Morales, JM; Rodicio, JL; Rodriguez Paternina, E | 1 |
| Fardel, O; Guillouzo, A; Ketterer, B; Loyer, P; Ratanasavanh, D | 1 |
| Bell, PR; Donnelly, PK; Feehally, J; Harper, SJ; Horsburgh, T; Moorhouse, J; Veitch, PS; Walls, J | 2 |
| Alivanis, P; Bougioukas, G; Grekas, D; Kalekou, H; Pyrpasopoulos, M; Tourkantonis, A | 1 |
| Alivanis, P; Grekas, D; Kalekou, H; Karamouzis, M; Papayianni, K; Tourkantonis, A | 1 |
| Donnelly, PK; Edwards, CM; Morgan, JD | 1 |
| Chan, CP; Huang, CC; Lai, MK; Pan, WL | 1 |
| Bernimoulin, JP; Hinz, N; Romanos, GE; Schröter-Kermani, C | 1 |
| Chagnac, A; Hirsh, J; Korzets, A; Levi, J; Ori, Y; Zevin, D | 1 |
| Abu-Romeh, SH; el-Khatib, D; Fayyad, M; Higazi, AS; Osman, N; Patel, M; Rashid, A; Scheikhoni, A | 1 |
| Hunt, CM; Stave, GM; Westerkam, WR | 1 |
| Geró, S; Horváth, M; Jósfay, A; Mezey, Z; Nánay, I; Varsányi, M | 1 |
| Feehally, J; Horsburgh, T; McNally, PG; Walls, J | 1 |
| Hartz, PA; Wilson, PD | 1 |
| Braun, T; Sponholz, F; Sponholz, H | 1 |
| Dark, J; Ellis, JS; Idle, JR; Kelly, PJ; Parry, G; Seymour, RA; Thomason, JM | 1 |
| Hilbrands, LB; Hoitsma, AJ; Koene, RA | 1 |
| Chagnac, A; Gafter, U; Hirsh, J; Korzets, A; Levi, J; Weinstein, T; Zevin, D | 1 |
| Grenda, R; Januszewicz, P; Zawadzki, J | 1 |
| Bonnaure-Mallet, M; Godeau, GJ; Tricot-Doleux, S | 1 |
| Bates, SE; Meadows, BJ; Regis, JI; Robey, RW; Scala, S; Zhan, Z | 1 |
| Levine, RA; Rees, TD | 1 |
| Belitsky, P; Knox, MG; Methot, ME; Nicol, D; Sketris, IS | 1 |
| Ellis, JS; Seymour, RA; Thomason, JM | 1 |
| Andres, A; Araque, A; Hernandez, E; Morales, JM; Rodicio, JL; Rodriguez-Paternina, E; Ruilope, LM | 1 |
| Cambar, J; L'Azou, B; Lakhdar, B | 1 |
| Crocker, JF; LeVatte, TL; McLellan, DH; Renton, KW | 1 |
| Bell, PR; Donnelly, PK; Feehally, J; Furness, PN; Harper, SJ; McCulloch, TA; Moorhouse, J; Walls, J | 1 |
| Beer, JC; Evans, SJ; Lord, RH; Marsh, FP; Moore, R; Raftery, MJ; Wilkie, ME | 1 |
| Hilbrands, LB; Hoitsma, AJ; Huysmans, FT; Koene, RA; van Hamersvelt, HW; Wetzels, JF | 1 |
| Brown, RS; Ingles, E; Rossmann, JA | 1 |
| Jacobs, U; Klehr, HU; Klein, B | 1 |
| Huttunen, KR; Knuuttila, ML; Pernu, HE; Tiilikainen, AS | 1 |
| Albers, N; Beier, C; Bohnhorst, B; Bökenkamp, A; Brodehl, J; Offner, G | 1 |
| Johnson, RB; Odlum, O; Pylypas, SP; Zebrowski, EJ | 1 |
| Morales, JM; Rodicio, JL; Ruilope, LM | 1 |
| Beckingham, IJ; Dennis, MJ; Nicholson, ML; Smith, SJ | 1 |
| Ballardie, FW; Chalmers, RJ; Edwards, BD; Lawson, RS; O'Driscoll, J; Testa, HJ | 1 |
| Ballardie, FW; Chalmers, RJ; Daley-Yates, PT; Edwards, BD; Lawson, RS; Maiza, A; O'Driscoll, JB; Testa, HJ | 1 |
| Cardella, CJ; Leenen, FH; Legault, L; Ogilvie, RI | 1 |
| Mimran, A; Mourad, G; Ribstein, J | 1 |
| Rice, N; Seymour, RA; Thomason, JM | 1 |
| Bernimoulin, JP; Romanos, GE; Strub, JR | 1 |
| Donnelly, PK; Feehally, J; Furness, P; Harper, SJ; Horsburgh, T; Jurewicz, A; Kehinde, EO; McCullough, T; Moorhouse, J; Morgan, J | 1 |
| Barton, C; Beer, JC; Dawnay, A; Marsh, FP; Raftery, MJ; Wilkie, ME | 1 |
| Francis, DM; Fullinfaw, R; Higgins, TJ; King, GN; Walker, RG; Wiesenfeld, D | 1 |
| Angelini, C; Aroldi, A; Braga, M; Montagnino, G; Ponticelli, C; Tarantino, A | 1 |
| Adubor, C; Cheigh, JS; Fotino, M; Friedman, GS; Haschemeyer, RH; Riggio, RR; Saal, SD; Stubenbord, WT; Suthanthiran, M; Wang, JC | 1 |
| Curtis, JJ; Gaston, RS; Jones, PA; Julian, BA; Laskow, DA; Luke, RG | 1 |
| Ader, JL; Durand, D; Lloveras, JJ; Rostaing, L; Suc, JM; Tack, I; Tran-Van, T | 1 |
| Aneiros, J; Caballero, T; Gómez-Morales, M; Lucena, MA; Mesa, F; Moreno, E; Navarro, N; O'Valle, F; Ramírez, C; Revelles, F | 1 |
| Abrams, K; Bell, PR; Combe, C; Donnelly, PK; Feehally, J; Harper, SJ; Harris, K; Horsburgh, T; Jurewicz, A; Moorhouse, J; Nicholson, M; Veitch, PS; Walls, J | 1 |
| Modéer, T; Sandberg, J; Wondimu, B | 1 |
| Cheigh, JS; Riggio, RR; Rubin, A; Serur, D; Shin, GT; Stenzel, KH; Stubenbord, WT; Suthanthiran, M; Wang, JC | 1 |
| Bell, PR; Feehally, J; Kehinde, EO; Nicholson, ML; Veitch, PS; Wheatley, T | 1 |
| Bártová, V; Hátle, K; Nĕmecek, K; Stípek, S; Zima, T | 1 |
| Ishida, H; Morisaki, I; Nagata, T; Nishikawa, S; Oka, T | 1 |
| Balakrishnan, VS; Coles, GA; Griffiths, DF; von Ruhland, CJ; Williams, JD | 1 |
| Dumas, C; Matha, V; Quiot, JM; Vey, A | 1 |
| Barbaro, A; Margiotta, V; Pizzo, G; Pizzo, I | 1 |
| Aydin, AE; Aygün, S; Carin, M; Cebeci, I; Firatli, E; Güç, U; Kantarci, A; Tanyeri, H; Tuncer, O | 1 |
| Berini, L; Brunet, L; Farré, M; Mendieta, C; Miranda, J | 1 |
| Darbar, UR; Hopper, C; Newman, HN; Speight, PM | 1 |
| Bariety, J; Bokas, S; Darlametsos, I; Gkika, EL; Gkikas, G; Hornych, A; Karageorgou, I; Morphake, P; Papanikolaou, N; Patsialos, K; Tsipas, G | 1 |
| Hamilton, JR; Lowry, LY; Seymour, RA; Waterhouse, PJ; Welbury, RR | 1 |
| Babich, S; Jackson, C | 1 |
| Gennari, PU; Macaluso, GM; Savi, A; Vescovi, P | 1 |
| Greenstein, SM; Kim, DY; Schechner, RS; Schreiber, TC; Sun, S; Tellis, VA | 1 |
| Khocht, A; Schneider, LC | 1 |
| Christians, U; Korn, A; Sperschneider, H; Wagner, C | 1 |
| Ellis, JS; Kelly, PJ; Seymour, RA; Thomason, JM | 1 |
| Bral, M; Santi, E | 1 |
| Botha, PJ | 1 |
| Desai, P; Silver, JG | 1 |
| Hall, EE | 1 |
| Ashley, FP; Koffman, CG; Morel, A; Ogg, CS; Rigden, SP; Smith, D; Wilson, RF | 1 |
| Hatase, O; Lu, YF; Matsui, H; Moriwaki, A; Onuma, H; Tokuda, M; Tomizawa, K | 1 |
| Camargo, PM; Carere, M; Carranza, FA; Pilloni, A | 1 |
| Mair, LH; Varga, E | 1 |
| Ferrari, P; Nohl, F | 1 |
| Elliott, HL; Feehally, J; Griffin, P; Moore, RJ; Olubodun, JO; Venkat-Raman, G; Wilkinson, R | 1 |
| Payne, VM | 1 |
| Furue, M; Koga, T; Nakayama, J | 1 |
| Chan, L; Jacob, LP; Malhotra, D; Shapiro, JI | 1 |
| Braun-Dullaeus, RC; Feussner, M; Grimminger, F; Haberbosch, W; Hopmann, H; Kraemer, HJ; Tillmanns, H; Walker, G | 1 |
| Knuuttila, ML; Nurmenniemi, PK; Pernu, HE | 3 |
| Abboud, C; Constine, L; DiPersio, J; Duerst, R; Liesveld, J; Linder, T; McKenna, B; Packman, C; Rapoport, A; Rowe, J; Silverman, W; Swift, S; Wedow, L; Zwetsch, L | 1 |
| Atilla, G; Baylas, H; Ilgenli, T | 1 |
| Dongari-Bagtzoglou, AI; Morton, RS | 1 |
| Caffesse, RG; Inglés, E; Rossmann, JA | 1 |
| Ak, G; Akar, U; Carin, M; Furuncuoglu, Y; Sever, MS; Seyhun, Y; Türk, S; Türkmen, A | 1 |
| Arai Furusawa, E; Cavalcante, JS; David-Neto, E; Ianhez, LE; Lemos, FBC; Romano, P; Schwartzman, BS; Yagyu, EM | 1 |
| Boomer, S; Campbell, BA; Hull, PS; Irwin, CR; Jamal, S; James, JA; Johnson, RW; Linden, GJ; Marley, JJ; Maxwell, AP; Short, CD; Spratt, H | 1 |
| He, J; Xiao, Y; Zhang, L | 1 |
| Amano, A; Daikoku, H; Fujimori, Y; Fukui, N; Morisaki, I; Murakami, J | 1 |
| Koski, T; Vilpo, J; Vilpo, L | 1 |
| Bobadilla, NA; Bolio, A; Gamba, G; Herrera-Acosta, J; Jiménez, F; Sánchez-Lozada, LG | 1 |
| Darlametsos, IE; Papanikolaou, EN; Varonos, DD | 1 |
| Gu, Z; Jiang, Q; Jing, G; Zhang, G | 1 |
| Donnelly, PK; Edwards, CM; Morgan, JD; Swarbrick, MJ | 1 |
| Knuuttila, ML; Pernu, HE | 1 |
| Arceci, R; Cianfriglia, M; Goda, K; Mechetner, E; Nagy, H; Szabó, G | 1 |
| Beighton, D; O'Brien, G; Roberts, GJ; Sheehy, EC | 1 |
| Chiang, CY; Chiu, HC; Fu, E; Liu, D | 1 |
| Baboolal, K; Newcombe, RG; Subramanian, N; Thomas, DW | 1 |
| Bjerkely, BL; Bryde, P; Fauchald, P; Foss, A; Hartmann, A; Holdaas, H; Ihlen, H; Midtvedt, K | 1 |
| Firatli, E; Hong, HH; Kantarci, A; Sheff, MC; Trackman, PC; Uygur, C; Uzel, MI | 1 |
| de Toledo, S; Duarte, PM; Nociti Júnior, FH; Nogueira Filho, GR; Sallum, AW; Sallum, EA | 1 |
| Martín-Comín, J; Nascimento Cardoso, V; Roca, M | 1 |
| Almeida, OP; Gonzaga, HF; Neves, KA; Spoildorio, LC; Spolidorio, DM | 1 |
| Sakai, K; Sato, F; Shitan, N; Ueda, K; Yazaki, K | 1 |
| Antonello, A; Calò, L; Davis, PA; Giacon, B; Huber, W; Pagnin, E; Piccin, A; Riegler, P; Semplicini, A | 1 |
| Kelly, D; McKaig, SJ; Shaw, L | 1 |
| Feres-Filho, EJ; Martins, RC; Rocha, LA; Silva, LC; Werneck, CC | 1 |
| Ansari, G; Einollahi, B; Khoori, AH; Moozeh, MB | 1 |
| Furness, PN; Murphy, GJ; Nicholson, ML; Sandford, RS; Waller, JR | 1 |
| Almeida, OP; Benatti, C; Sampaio, JE; Spolidorio, DM; Spolidorio, LC | 1 |
| Hilbrands, LB; Hoitsma, AJ; Koene, RA; Merkus, JW; Skotnicki, SH; van Asten, WN | 1 |
| Ferguson, CJ; Parry-Jones, DJ; Salaman, JR; von Ruhland, C; Williams, JD | 1 |
| Almeida, OP; Holzhausen, M; Nassar, CA; Nassar, PO; Spolidorio, DM; Spolidorio, LC | 1 |
| Boratyńska, M; Klinger, M; Radwan-Oczko, M; Zietek, M | 1 |
| Kantarci, A; Trackman, PC | 1 |
| Bénitah, JP; Perrier, E; Perrier, R; Richard, S | 1 |
| Ishikawa, A; Kawabe, K; Kitamura, T; Ohta, N; Ozono, S | 1 |
| Chander, V; Chopra, K | 1 |
| Giusto, TJ | 1 |
| Flynn, JC; Henderson, JS; Johnson, RB | 1 |
| Gordon, G; Hosey, MT; Kelly, DA; Shaw, L | 1 |
| Buduneli, E; Buduneli, N; Cinar, S; Kinane, DF; Lappin, D | 1 |
| Häkkinen, L; Knuuttila, M; Larjava, H; Pernu, H; Walsh, P | 1 |
| Battino, M; Bullon, P; Gallardo, I; Goteri, G; Newman, HN; Ribas, J; Rubini, C | 1 |
| Bahamondes, C; Godoy, J | 1 |
| Augustin, P; Firatli, E; Graves, DT; Hasturk, H; Kantarci, A; Sheff, MC; Trackman, PC | 1 |
| Catterall, J; Cawston, TE; Jones, D; Lakey, R; Seymour, RA; Sukkar, TZ; Thomason, JM | 1 |
| Iwasaki, K | 1 |
| Lovel, SF; Melrose, CA; Walker, MR | 1 |
| Castro, AL; Crivelini, MM; Garcia, JF; Kanno, CM; Oliveira, JA | 1 |
| Bhattacharyya, I; Cohen, D | 1 |
| Dorababu, M; Naruhashi, K; Nishimura, A; Prabha, T; Shibata, N; Sugioka, N; Takada, K | 1 |
| Haas Jimoh Akanbi, M; Meter-Arkema, A; Post, E; Rink, R; Robillard, GT; Scholtmeijer, K; Wang, X; Wösten, HA | 1 |
| Kantarci, A; Kim, YS; Nseir, Z; Sume, SS; Trackman, PC | 1 |
| Ashrafi, SS; Nakib, N | 1 |
| Gieseg, SP; Whiteman, M; Yang, YT | 1 |
| Huang, HB; Lai, NS; Lu, MC; Tung, CH; Yin, WY; Yu, CL; Yu, HC | 1 |
| Abreu, IN; Andreazza, NL; Mazzafera, P; Sawaya, AC | 1 |
| Dahlgren, D; Lennernäs, H; Roos, C; Sjögren, E | 1 |
| Eid, AA; El-Mas, MM; Hammoud, SH; Omar, AG | 1 |
| Alkhansa, S; Eid, AA; El-Mas, MM; Hammoud, SH; Mahjoub, N; Omar, AG | 1 |
| Bian, Z; Fang, YJ; Meng, LY; Tay, FR; Zhao, XH | 1 |
| Ervolino, E; Kanno, CM; Oliveira, JA; Soubhia, AMP | 1 |
| Song, J; Wang, X; Wu, J; Zhang, R; Zhu, J | 1 |
| Droździk, A; Droździk, M | 1 |
17 review(s) available for nifedipine and cyclosporine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Emerging New Targets for the Treatment of Resistant Fungal Infections.
Topics: Antifungal Agents; Drug Resistance, Fungal; Humans; Molecular Targeted Therapy; Mycoses | 2018 |
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells | 2022 |
Chemoresistance in the clinic: overview 1994.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Dipyridamole; Drug Resistance, Multiple; Glutathione; Humans; Neoplasms; Nifedipine; Verapamil | 1994 |
Systematic drugs as a risk factor for periodontal disease initiation and progression.
Topics: Calcium Channel Blockers; Cyclosporine; Female; Fibromatosis, Gingival; Gingival Hyperplasia; Gonadal Steroid Hormones; Humans; Male; Nifedipine; Phenytoin | 1995 |
Oral and dental problems in the organ transplant patient.
Topics: Anti-Bacterial Agents; Cyclosporine; Dental Care for Chronically Ill; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Nifedipine; Organ Transplantation; Periodontal Diseases; Premedication | 1994 |
Lipophilic dihydropyridines provide renal protection from cyclosporin toxicity.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Cyclosporine; Dihydropyridines; Humans; Kidney; Kidney Transplantation; Nifedipine | 1993 |
Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model.
Topics: Age Factors; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Plaque; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Gingival Hyperplasia; Gingivitis; Humans; Immunosuppressive Agents; Male; Nifedipine; Phenytoin; Rats; Rats, Inbred F344; Sex Factors; Specific Pathogen-Free Organisms | 1996 |
Gingival enlargement induced by drugs.
Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin | 1996 |
Drug-induced gingival hyperplasia and its management--a literature review.
Topics: Anticonvulsants; Calcium Channel Blockers; Clinical Protocols; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin | 1997 |
Drug-induced gingival enlargements.
Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Overgrowth; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin; Verapamil | 1998 |
Prevention and treatment considerations in patients with drug-induced gingival enlargement.
Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Prophylaxis; Gingival Overgrowth; Gingivectomy; Humans; Immunosuppressive Agents; Nifedipine; Oral Hygiene; Phenytoin | 1997 |
Connective tissue metabolism and gingival overgrowth.
Topics: Animals; Anticonvulsants; Antihypertensive Agents; Connective Tissue; Connective Tissue Growth Factor; Cyclosporine; Extracellular Matrix; Fibroblasts; Gingival Overgrowth; Growth Substances; Humans; Immediate-Early Proteins; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Nifedipine; Phagocytosis; Phenytoin | 2004 |
Metabolism of tacrolimus (FK506) and recent topics in clinical pharmacokinetics.
Topics: Biotransformation; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Monitoring; Enzyme Inhibitors; Humans; Immunoenzyme Techniques; Immunosuppressive Agents; Ketoconazole; Molecular Structure; Nifedipine; Polymorphism, Single Nucleotide; Tacrolimus | 2007 |
Drug-induced gingival overgrowth.
Topics: Adult; Anticonvulsants; Calcium Channel Blockers; Child; Cyclosporine; Gingiva; Gingival Overgrowth; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin; Prevalence; Risk Factors | 2011 |
Bibliometric analysis of research trends and characteristics of drug-induced gingival overgrowth.
Topics: Amlodipine; Anticonvulsants; Bibliometrics; Calcium Channel Blockers; Cyclosporine; Gingival Overgrowth; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin | 2022 |
Drug-Induced Gingival Overgrowth-Molecular Aspects of Drug Actions.
Topics: Calcium Channel Blockers; Cyclosporine; Fibroblasts; Gingiva; Gingival Overgrowth; Humans; Nifedipine | 2023 |
32 trial(s) available for nifedipine and cyclosporine
| Article | Year |
|---|---|
Effect of endothelin-1 in man: pretreatment with nifedipine, with indomethacin and with cyclosporine A.
Topics: Adult; Blood Pressure; Calcium Channels; Cyclosporine; Drug Interactions; Endothelins; Humans; Indomethacin; Infusions, Intravenous; Male; Nifedipine; Potassium | 1992 |
Calcium antagonist therapy prevents chronic cyclosporine nephrotoxicity after renal transplantation: a prospective study.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Creatinine; Cyclosporine; Female; Follow-Up Studies; Humans; Immunosuppression Therapy; Kidney Function Tests; Kidney Transplantation; Male; Natriuresis; Nifedipine; Prospective Studies | 1992 |
Improved immediate graft function with nifedipine in cyclosporine-treated renal allograft recipients--a randomized prospective study.
Topics: Cadaver; Cyclosporine; Graft Survival; Humans; Kidney Transplantation; Nifedipine; Prospective Studies; Tissue Donors; Transplantation, Homologous | 1992 |
Cyclosporine-related hypercoagulability: fact or fiction?
Topics: Adolescent; Adult; Aged; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Graft Rejection; Graft Survival; Humans; Kidney Transplantation; Male; Middle Aged; Nifedipine; Postoperative Complications; Prednisone; Prospective Studies; Thrombelastography; Thromboembolism | 1992 |
Comparative effects of enalapril and nifedipine on renal hemodynamics in hypertensive renal allograft recipients.
Topics: Adult; Azathioprine; Cyclosporine; Enalapril; Female; Humans; Hypertension, Renal; Kidney Transplantation; Male; Middle Aged; Nifedipine; Prospective Studies; Renal Circulation | 1992 |
Medication compliance after renal transplantation.
Topics: Adult; Antihypertensive Agents; Atenolol; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Patient Compliance; Prednisone; Prospective Studies; Time Factors; Treatment Refusal | 1995 |
Chemoresistance in the clinic: overview 1994.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Dipyridamole; Drug Resistance, Multiple; Glutathione; Humans; Neoplasms; Nifedipine; Verapamil | 1994 |
Long-term protective effect of a calcium antagonist on renal function in hypertensive renal transplant patients on cyclosporine therapy: a 5-year prospective randomized study.
Topics: Analysis of Variance; Antihypertensive Agents; Cadaver; Creatinine; Cyclosporine; Female; Follow-Up Studies; Graft Survival; Humans; Hypertension; Kidney Transplantation; Male; Nifedipine; Prospective Studies; Survival Rate; Time Factors; Tissue Donors | 1994 |
Influence of nifedipine on interstitial fibrosis in renal transplant allografts treated with cyclosporin A.
Topics: Azathioprine; Cyclosporine; Fibrosis; Glomerular Filtration Rate; Humans; Immunosuppression Therapy; Kidney; Kidney Transplantation; Nifedipine; Single-Blind Method; Time Factors | 1994 |
A double-blind, randomized, placebo-controlled study of nifedipine on early renal allograft function.
Topics: Adult; Cyclosporine; Female; Glomerulonephritis; Graft Rejection; Graft Survival; Humans; Kidney; Kidney Transplantation; Male; Middle Aged; Nifedipine; Postoperative Complications; Time Factors | 1994 |
Acute effects of nifedipine in renal transplant recipients treated with cyclosporine or azathioprine.
Topics: Azathioprine; Blood Pressure; Cyclosporine; Diuresis; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Transplantation; Male; Nifedipine; Renal Plasma Flow; Vasoconstriction | 1994 |
Calcium antagonists in heart transplant recipients: effects on cardiac and renal function and cyclosporine pharmacokinetics.
Topics: Cyclosporine; Diltiazem; Heart Transplantation; Hemodynamics; Humans; Hypertension; Immunosuppression Therapy; Kidney; Kidney Function Tests; Male; Middle Aged; Nifedipine | 1993 |
Converting-enzyme inhibitor versus calcium antagonist in cyclosporine-treated renal transplants.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cyclosporine; Dipeptides; Female; Humans; Hypertension; Kidney; Kidney Transplantation; Lisinopril; Male; Middle Aged; Nifedipine; Prospective Studies | 1993 |
Renal transplantation: nifedipine for the nonstarters? A prospective randomised study.
Topics: Adult; Biopsy; Creatinine; Cyclosporine; Drug Administration Schedule; Histocompatibility Testing; Humans; Kidney Transplantation; Middle Aged; Nifedipine; Prospective Studies; Time Factors; Transplantation, Homologous | 1993 |
Effect of nifedipine on renal haemodynamics and urinary protein excretion in stable renal transplant recipients.
Topics: Adult; Azathioprine; Blood Pressure; Creatinine; Cyclosporine; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Nifedipine; Prednisolone; Proteinuria; Regional Blood Flow; Renal Circulation; Time Factors; Transplantation, Homologous; Vascular Resistance | 1993 |
Captopril-induced fall in glomerular filtration rate in cyclosporine-treated hypertensive patients.
Topics: Adult; Blood Pressure; Captopril; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Transplantation; Male; Nifedipine; Postoperative Period | 1993 |
Renal functional reserve in calcium channel blocker-treated hypertensive recipients of kidney transplant.
Topics: Adult; Amino Acids; Calcium Channel Blockers; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Hypertension, Renal; Isradipine; Kidney Transplantation; Male; Middle Aged; Nifedipine; Nitrendipine; Renal Plasma Flow; Retrospective Studies | 1995 |
The beneficial effects of oral nifedipine on cyclosporin-treated renal transplant recipients--a randomised prospective study.
Topics: Administration, Oral; Adult; Calcium Channel Blockers; Creatinine; Cyclosporine; Drug Therapy, Combination; Follow-Up Studies; Glomerular Filtration Rate; Graft Rejection; Graft Survival; Hemodynamics; Humans; Immunosuppressive Agents; Kidney Transplantation; Middle Aged; Nifedipine; Prospective Studies; Survival Rate | 1996 |
Gingival overgrowth in renal transplant patients administered cyclosporin A in mixture or in capsule form. A longitudinal study.
Topics: Adult; Aged; Calcium Channel Blockers; Capsules; Cyclosporine; Female; Gingiva; Humans; Immunosuppressive Agents; Kidney Transplantation; Longitudinal Studies; Male; Middle Aged; Nifedipine; Random Allocation | 1996 |
Long-term beneficial effects of a nifedipine-supplemented immunosuppressive regimen in kidney transplantation.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Creatinine; Cyclosporine; Female; Follow-Up Studies; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Survival Rate | 1996 |
Immunosuppression for recipients of kidneys from non-heart-beating donors: comparison of triple therapy and OKT3 regimens.
Topics: Aged; Azathioprine; Cadaver; Calcium Channel Blockers; Costs and Cost Analysis; Cyclosporine; Drug Therapy, Combination; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Muromonab-CD3; Nifedipine; Prednisolone; Time Factors; Tissue Donors; United States | 1996 |
[Effect of diltiazem on concentration of cyclosporin metabolites in Sandimmune and Neoral treated kidney transplant patients].
Topics: Adult; Biotransformation; Calcium Channel Blockers; Cyclosporine; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Metabolic Clearance Rate; Middle Aged; Nifedipine; Prospective Studies; Structure-Activity Relationship | 1997 |
Surgical treatment of cyclosporine A- and nifedipine-induced gingival enlargement: gingivectomy versus periodontal flap.
Topics: Adolescent; Adult; Calcium Channel Blockers; Child; Cyclosporine; Female; Gingival Hyperplasia; Gingivectomy; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Periodontal Index; Periodontal Pocket; Surgical Flaps | 1998 |
Renal and haemodynamic effects of amlodipine and nifedipine in hypertensive renal transplant recipients.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Cyclosporine; Female; Follow-Up Studies; Glomerular Filtration Rate; Graft Rejection; Humans; Hypertension; Kidney; Kidney Transplantation; Male; Middle Aged; Nifedipine; Renal Plasma Flow; Single-Blind Method | 1998 |
Long-term efficacy and adverse event of nifedipine sustained-release tablets for cyclosporin A-induced hypertension in patients with psoriasis.
Topics: Adult; Aged; Blood Pressure Determination; Calcium Channel Blockers; Cyclosporine; Delayed-Action Preparations; Drug Therapy, Combination; Female; Follow-Up Studies; Gingival Hyperplasia; Humans; Hyperlipidemias; Hypertension; Kidney Function Tests; Long-Term Care; Male; Middle Aged; Nifedipine; Psoriasis; Treatment Outcome | 1998 |
Cyclosporin, nifedipine and gingival hyperplasia: a randomized controlled study.
Topics: Calcium Channel Blockers; Cyclosporine; Drug Interactions; Gingival Hyperplasia; Gingivectomy; Humans; Immunosuppressive Agents; Kidney Transplantation; Nifedipine; Oral Hygiene | 1994 |
Reduction of left ventricular mass by lisinopril and nifedipine in hypertensive renal transplant recipients: a prospective randomized double-blind study.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Cyclosporine; Delayed-Action Preparations; Double-Blind Method; Echocardiography; Female; Heart; Heart Ventricles; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Lisinopril; Male; Middle Aged; Nifedipine; Prospective Studies; Time Factors | 2001 |
Oxidative stress and TGFbeta in kidney-transplanted patients with cyclosporin-induced hypertension. Effect of carvedilol and nifedipine.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Carbazoles; Carvedilol; Cyclosporine; Drug Evaluation; Female; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Membrane Proteins; Middle Aged; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Postoperative Complications; Propanolamines; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Treatment Outcome; Tyrosine | 2002 |
Investigation of the effect of FK506 (tacrolimus) and cyclosporin on gingival overgrowth following paediatric liver transplantation.
Topics: Adolescent; Analysis of Variance; Calcium Channel Blockers; Child; Child, Preschool; Cyclosporine; Double-Blind Method; Gingiva; Gingival Overgrowth; Humans; Immunosuppressive Agents; Infant; Liver Transplantation; Nifedipine; Prospective Studies; Statistics, Nonparametric; Tacrolimus | 2002 |
Randomized clinical trial of the effect of microemulsion cyclosporin and tacrolimus on renal allograft fibrosis.
Topics: Adult; Analysis of Variance; Aspirin; Cyclosporine; Extracellular Matrix; Female; Fibrosis; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Prednisolone; Prospective Studies; Tacrolimus; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination | 2003 |
Nifedipine improves immediate, and 6- and 12-month graft function in cyclosporin A (CyA) treated renal allograft recipients.
Topics: Adult; Calcium Channel Blockers; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Glomerular Filtration Rate; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Nifedipine; Renal Circulation; Time Factors; Transplantation, Homologous | 1992 |
Inhibition of plasminogen activator inhibitor-1 by angiotensin II receptor blockers on cyclosporine-treated renal allograft recipients.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Creatinine; Cyclosporine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Transplantation; Losartan; Male; Middle Aged; Nifedipine; Plasminogen Activator Inhibitor 1; Tetrazoles; Transplantation, Homologous | 2005 |
134 other study(ies) available for nifedipine and cyclosporine
| Article | Year |
|---|---|
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
The restoration of ATP synthesis may explain the protective effect of calcium antagonists against cyclosporine A nephrotoxicity.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Cyclosporine; Kidney; Kidney Diseases; Mitochondria, Liver; Nifedipine; Oxygen Consumption; Rats; Verapamil | 1992 |
Overexpression of the multidrug resistance gene product in adult rat hepatocytes during primary culture.
Topics: Amitriptyline; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Cell Membrane; Cell Survival; Cells, Cultured; Cyclosporine; Doxorubicin; Drug Resistance; Gene Expression; Liver; Male; Membrane Glycoproteins; Nifedipine; Quinidine; Rats; Rats, Inbred Strains; RNA, Messenger; Verapamil; Vincristine | 1992 |
Reduction of CyA nephrotoxicity by nifedipine during and after experimental in situ renal preservation.
Topics: Animals; Cyclosporine; Dogs; Drug Interactions; Ischemia; Kidney; Nifedipine; Organ Preservation; Perfusion; Time Factors; Vasoconstriction | 1992 |
Acute cyclosporin A renal dysfunction in dogs reversed by calcium antagonists and antiplatelet agents.
Topics: Animals; Calcium Channel Blockers; Cyclosporine; Dogs; Drug Interactions; Kidney; Kidney Tubular Necrosis, Acute; Nifedipine; Piracetam; Platelet Aggregation Inhibitors; Thromboxane A2; Thromboxane B2; Time Factors; Vasoconstriction | 1992 |
Cyclosporine-induced gingival overgrowth.
Topics: Cyclosporine; Dental Plaque; Gingival Hypertrophy; Humans; Immunosuppressive Agents; Kidney Transplantation; Nifedipine | 1992 |
Distribution of fibronectin in healthy, inflamed and drug-induced gingival hyperplasia.
Topics: Actin Cytoskeleton; Adult; Connective Tissue; Connective Tissue Cells; Cyclosporine; Dental Plaque; Epithelium; Female; Fibronectins; Fluorescent Antibody Technique; Gingiva; Gingival Hemorrhage; Gingival Hyperplasia; Gingival Pocket; Gingivitis; Humans; Male; Middle Aged; Nifedipine; Phenytoin | 1992 |
The effect of high-dose nifedipine on renal hemodynamics of cyclosporine-treated renal allograft recipients.
Topics: Adult; Cyclosporine; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Kidney; Kidney Transplantation; Male; Middle Aged; Nifedipine; Renal Circulation; Transplantation, Homologous | 1992 |
Effect of age and gender on the activity of human hepatic CYP3A.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Aryl Hydrocarbon Hydroxylases; Body Weight; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diltiazem; Humans; Lidocaine; Microsomes, Liver; Middle Aged; Nifedipine; Oxidoreductases, N-Demethylating; Quinidine; Sex Factors; Smoking | 1992 |
The effect of some drugs on in vitro cellular immune reactions and on circulating immune complexes in patients with myocardial infarction.
Topics: Aged; Antigen-Antibody Complex; Aorta; Cell Migration Inhibition; Clofibric Acid; Cyclosporine; Female; Humans; Hypolipidemic Agents; Immunity, Cellular; In Vitro Techniques; Lipoproteins, LDL; Male; Middle Aged; Myocardial Infarction; Nifedipine | 1991 |
Nifedipine does not inhibit ciclosporin A uptake into human cultured proximal tubular cells.
Topics: Biological Transport, Active; Cells, Cultured; Cyclosporine; Humans; Kidney Tubules, Proximal; Nifedipine | 1991 |
Mechanisms of cyclosporine A toxicity in defined cultures of renal tubule epithelia: a role for cysteine proteases.
Topics: Animals; Calcium; Cell Death; Cells, Cultured; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diltiazem; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Humans; Kidney Diseases; Kidney Tubules; Leucine; Microscopy, Fluorescence; Nifedipine; Rabbits; Time Factors; Verapamil | 1991 |
[Side effects of the immunsuppressive cyclosporin A in dentistry].
Topics: Adult; Cyclosporine; Female; Gingival Hyperplasia; Humans; Kidney Transplantation; Male; Middle Aged; Nifedipine | 1991 |
Iatrogenic gingival overgrowth in cardiac transplantation.
Topics: Adolescent; Adult; Age Factors; Calcium Channel Blockers; Cyclosporine; Drug Synergism; Female; Gingival Crevicular Fluid; Gingival Hemorrhage; Gingival Hyperplasia; Gingivectomy; Heart Transplantation; Humans; Iatrogenic Disease; Immunosuppressive Agents; Logistic Models; Male; Middle Aged; Nifedipine; Periodontal Index; Periodontal Pocket; Risk Factors; Sex Factors | 1995 |
Effect of nifedipine on the renal functional reserve in cyclosporine-treated renal-transplant recipients.
Topics: Adult; Amino Acids; Cyclosporine; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Nifedipine; Renal Circulation; Vasodilator Agents | 1995 |
Effect of nifedipine on tubular handling of uric acid in transplanted kidney on cyclosporine A treatment.
Topics: Adolescent; Adult; Child; Creatinine; Cyclosporine; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Ion Transport; Kidney Diseases; Kidney Transplantation; Kidney Tubules; Male; Nifedipine; Probenecid; Uric Acid | 1995 |
Grapefruit juice interactions with drugs.
Topics: Beverages; Caffeine; Citrus; Cyclosporine; Estrogens; Felodipine; Food-Drug Interactions; Humans; Midazolam; Nifedipine; Terfenadine | 1995 |
Changes in extracellular matrix macromolecules in human gingiva after treatment with drugs inducing gingival overgrowth.
Topics: Collagen; Cyclosporine; Elastic Tissue; Elastin; Extracellular Matrix; Extracellular Matrix Proteins; Female; Fibroblasts; Fibronectins; Gingival Hyperplasia; Humans; Hydantoins; Male; Microscopy, Video; Nifedipine; Nitrendipine; Signal Processing, Computer-Assisted; Statistics, Nonparametric | 1995 |
Effect of calcium-channel blockers on cyclosporine clearance and use in renal transplant patients.
Topics: Administration, Oral; Adult; Calcium Channel Blockers; Cyclosporine; Diltiazem; Drug Interactions; Female; Graft Survival; Humans; Immunosuppression Therapy; Infusions, Intravenous; Kidney; Kidney Transplantation; Male; Middle Aged; Nifedipine; Nova Scotia; Retrospective Studies; Time Factors; Verapamil | 1994 |
Use of two in vitro glomerular models to study the renal vasoreactivity of cyclosporine.
Topics: Analysis of Variance; Animals; Calcium Channel Blockers; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Felodipine; Glomerular Mesangium; In Vitro Techniques; Kidney Cortex; Kidney Glomerulus; Kinetics; Nifedipine; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstriction; Verapamil | 1994 |
The interaction of the calcium channel blockers verapamil and nifedipine with cyclosporin A in pediatric renal transplant patients.
Topics: Adolescent; Child; Child, Preschool; Cyclosporine; Drug Interactions; Graft Rejection; Half-Life; Humans; Hypertension; Kidney Transplantation; Nifedipine; Verapamil | 1994 |
Multimodal treatment of drug-induced gingival hyperplasia in a kidney transplant patient.
Topics: Adult; Chlorhexidine; Cyclosporine; Dental Care for Chronically Ill; Dental Plaque; Drug Interactions; Folic Acid; Gingival Hyperplasia; Gingivectomy; Humans; Kidney Transplantation; Laser Therapy; Male; Nifedipine; Patient Care Planning | 1994 |
Cumulative side effects of cyclosporine and Ca antagonists: hypergalactinemia, mastadenoma, and gynecomastia.
Topics: Adenoma; Adult; Aged; Breast Neoplasms, Male; Calcium Channel Blockers; Cyclosporine; Diltiazem; Drug Synergism; Female; Galactorrhea; Gynecomastia; Humans; Kidney Transplantation; Male; Middle Aged; Nifedipine; Nitrendipine | 1994 |
Drug-induced gingival overgrowth and class II major histocompatibility antigens.
Topics: Adult; Amlodipine; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Felodipine; Female; Gingiva; Gingival Diseases; Histocompatibility Testing; HLA-DR Antigens; Humans; Kidney Transplantation; Male; Nifedipine; Retrospective Studies; Risk Factors | 1994 |
Nifedipine aggravates cyclosporine A-induced gingival hyperplasia.
Topics: Adolescent; Adult; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Gingival Hyperplasia; Graft Rejection; Humans; Hydralazine; Hypertension; Kidney Transplantation; Male; Nifedipine | 1994 |
Comparative metabolism of 3H-glucosamine by fibroblast populations exposed to cyclosporine.
Topics: Adult; Cell Count; Cells, Cultured; Chronic Disease; Cyclosporine; Extracellular Matrix; Fibroblasts; Gingiva; Gingival Hyperplasia; Glucosamine; Humans; Kidney Transplantation; Male; Nifedipine; Proteoglycans; Tritium | 1994 |
Effect of nifedipine on renal transplant rejection.
Topics: Adolescent; Adult; Aged; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Incidence; Kidney; Kidney Transplantation; Male; Middle Aged; Multivariate Analysis; Nifedipine; Prospective Studies; Retrospective Studies; Time Factors | 1993 |
Modulation of abnormalities in renal haemodynamics and vasoactive mediators by nifedipine in patients with psoriasis on low-dose cyclosporin.
Topics: Adolescent; Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Cyclosporine; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Hemodynamics; Hormones; Humans; Male; Middle Aged; Nifedipine; Psoriasis; Renal Circulation | 1993 |
Altered clearance of N-1 methylnicotinamide associated with the use of low doses of cyclosporine.
Topics: Analysis of Variance; Cyclosporine; Drug Therapy, Combination; Humans; Kidney Function Tests; Kidney Tubules, Proximal; Metabolic Clearance Rate; Niacinamide; Nifedipine; Renal Circulation | 1994 |
The prevalence and severity of cyclosporin and nifedipine-induced gingival overgrowth.
Topics: Adult; Cohort Studies; Cyclosporine; Dental Plaque Index; Drug Combinations; Female; Gingival Hemorrhage; Gingival Hyperplasia; Humans; Kidney Transplantation; Male; Middle Aged; Nifedipine; Oral Hygiene; Periodontal Index; Prevalence | 1993 |
Immunohistochemical distribution of extracellular matrix proteins as a diagnostic parameter in healthy and diseased gingiva.
Topics: Adult; Aged; Collagen; Cyclosporine; Extracellular Matrix Proteins; Female; Fibronectins; Fluorescent Antibody Technique; Gingiva; Gingival Hyperplasia; Gingivitis; Glycoproteins; Humans; Immunohistochemistry; Male; Microscopy, Fluorescence; Middle Aged; Nifedipine; Phenytoin | 1993 |
Gingival hyperplasia in renal allograft recipients receiving cyclosporin-A and calcium antagonists.
Topics: Adult; Cross-Sectional Studies; Cyclosporine; Dental Calculus; Dental Plaque Index; Diltiazem; Drug Interactions; Female; Gingival Hyperplasia; Humans; Hypertension; Kidney Transplantation; Male; Middle Aged; Models, Dental; Nifedipine; Periodontal Index; Saliva | 1993 |
Hypertension after renal transplantation.
Topics: Adult; Analysis of Variance; Antihypertensive Agents; Creatinine; Cyclosporine; Female; Graft Rejection; Humans; Hypertension; Kidney Transplantation; Logistic Models; Male; Middle Aged; Nifedipine; Prevalence | 1993 |
Excellent outcome with a calcium channel blocker-supplemented immunosuppressive regimen in cadaveric renal transplantation. A potential strategy to avoid antibody induction protocols.
Topics: Adult; Antibodies, Monoclonal; Azathioprine; Cadaver; Calcium Channel Blockers; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Nifedipine; Prednisone; Survival Rate; Transplantation, Homologous | 1993 |
Gingival overgrowth induced by nifedipine and cyclosporin A. Clinical and morphometric study with image analysis.
Topics: Adult; Calcium Channel Blockers; Case-Control Studies; Cyclosporine; Drug Synergism; Female; Follow-Up Studies; Gingiva; Gingival Hyperplasia; Humans; Image Processing, Computer-Assisted; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Nifedipine; Observer Variation; Periodontal Index; Photography; Reproducibility of Results; Signal Processing, Computer-Assisted | 1995 |
The effect of calcium channel blockers on cyclosporine A (Cs A) induced nephrotoxicity in rats.
Topics: Animals; Calcium Channel Blockers; Creatinine; Cyclosporine; Glomerular Filtration Rate; Kidney; Male; Nifedipine; Rats; Rats, Wistar; Verapamil | 1995 |
Effects of a selective adenosine A1 receptor antagonist on the development of cyclosporin nephrotoxicity.
Topics: Animals; Blood Pressure; Cyclosporine; Drug Interactions; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney Diseases; Male; Nifedipine; Purinergic Antagonists; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Renal Plasma Flow, Effective; Vasodilator Agents | 1996 |
Effects of destruxins, cyclic depsipeptide mycotoxins, on calcium balance and phosphorylation of intracellular proteins in lepidopteran cell lines.
Topics: Animals; Baculoviridae; Butterflies; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cell Line; Chelating Agents; Cyclosporine; Cytosol; Depsipeptides; Edetic Acid; Fungal Proteins; Humans; Immunosuppressive Agents; Ionophores; Mitosporic Fungi; Mycotoxins; Nifedipine; Peptides, Cyclic; Phosphorylation; Proteins | 1996 |
Cyclosporin- and nifedipine-induced gingival overgrowth in renal transplant patients: correlations with periodontal and pharmacological parameters, and HLA-antigens.
Topics: Adolescent; Adult; Azathioprine; Calcium Channel Blockers; Child; Cyclosporine; Dental Calculus; Dental Plaque Index; Disease Susceptibility; Female; Gingival Overgrowth; Gingivitis; HLA Antigens; HLA-A Antigens; Humans; Immunosuppressive Agents; Irritants; Kidney Transplantation; Male; Middle Aged; Nifedipine; Periodontal Index; Periodontal Pocket; Prevalence; Saliva | 1996 |
Evaluation of the frequency of HLA determinants in patients with gingival overgrowth induced by cyclosporine-A.
Topics: Adult; Antigenic Variation; Calcium Channel Blockers; Chi-Square Distribution; Cyclosporine; Diltiazem; Disease Susceptibility; Drug Combinations; Female; Gingival Overgrowth; HLA Antigens; HLA-DR1 Antigen; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Pharmacogenetics; Statistics, Nonparametric; Verapamil | 1996 |
Combined treatment approach to gingival overgrowth due to drug therapy.
Topics: Blood Loss, Surgical; Calcium Channel Blockers; Carbon Dioxide; Cyclosporine; Gingival Hemorrhage; Gingival Hyperplasia; Gingival Hypertrophy; Gingival Overgrowth; Gingivectomy; Heart Transplantation; Hemostasis, Surgical; Humans; Immunosuppressive Agents; Laser Coagulation; Male; Middle Aged; Nifedipine; Splints | 1996 |
Effects of OKY-046 and nifedipine in cyclosporine-induced renal dysfunction in rats.
Topics: Animals; Calcium Channel Blockers; Creatinine; Cyclosporine; Drug Interactions; Eicosanoids; Enzyme Inhibitors; Fatty Acids, Essential; Female; gamma-Linolenic Acid; Immunosuppressive Agents; Ketanserin; Kidney Function Tests; Kidney Tubules; Linoleic Acids; Metabolic Clearance Rate; Methacrylates; Nifedipine; Oenothera biennis; Plant Oils; Rats; Rats, Wistar; Renal Insufficiency | 1996 |
Gingival overgrowth in paediatric cardiac transplant patients: a study of 19 patients aged between 2 and 16 years.
Topics: Adolescent; Calcium Channel Blockers; Child; Child, Preschool; Cyclosporine; Dental Care for Chronically Ill; England; Female; Gingival Hyperplasia; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Nifedipine; Prevalence | 1995 |
Gingival hyperplasia: interaction between cyclosporin A and nifedipine? A case report.
Topics: Calcium Channel Blockers; Cyclosporine; Drug Synergism; Female; Gingival Hyperplasia; Gingival Pocket; Gingivectomy; Humans; Immunosuppressive Agents; Middle Aged; Nifedipine | 1997 |
[Gingival hypertrophy due to cyclosporine. A clinico-statistical study in 82 patients].
Topics: Adolescent; Adult; Calcium Channel Blockers; Cyclosporine; DMF Index; Drug Therapy, Combination; Female; Gingival Hypertrophy; Humans; Immunosuppressive Agents; Kidney Transplantation; Liver Transplantation; Male; Middle Aged; Nifedipine; Oral Health | 1997 |
Nifedipine protects small intestine from cyclosporine-induced hemodynamic and functional impairment.
Topics: Animals; Calcium Channel Blockers; Cyclosporine; Hemodynamics; Intestine, Small; Intestines; Maltose; Nifedipine; Rats; Rats, Inbred Lew; Regional Blood Flow; Vascular Resistance | 1997 |
Periodontal management of gingival overgrowth in the heart transplant patient: a case report.
Topics: Calcium Channel Blockers; Candidiasis, Oral; Connective Tissue; Cyclosporine; Epithelium; Fibrosis; Follow-Up Studies; Gingival Hyperplasia; Gingival Hypertrophy; Gingival Overgrowth; Gingivectomy; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Nifedipine; Stomatitis | 1997 |
Nifedipine pharmacological variables as risk factors for gingival overgrowth in organ-transplant patients.
Topics: Adult; Calcium Channel Blockers; Chi-Square Distribution; Cyclosporine; Dental Plaque Index; Dose-Response Relationship, Drug; Drug Combinations; Female; Gingival Crevicular Fluid; Gingival Overgrowth; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Nifedipine; Periodontal Index; Regression Analysis; Risk Factors; Statistics, Nonparametric | 1997 |
Effect of treatment on cyclosporine- and nifedipine-induced gingival enlargement: clinical and histologic results.
Topics: Adult; Aged; Anti-Infective Agents, Local; Chlorhexidine; Combined Modality Therapy; Cyclosporine; Dental Scaling; Drug Therapy, Combination; Gingival Hyperplasia; Gingivectomy; Humans; Immunosuppressive Agents; Male; Mouthwashes; Nifedipine; Surgical Flaps; Vasodilator Agents | 1998 |
Contribution of individual drugs to gingival overgrowth in adult and juvenile renal transplant patients treated with multiple therapy.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Azathioprine; Body Weight; Calcium Channel Blockers; Child; Child, Preschool; Cyclosporine; Dental Plaque; Drug Combinations; Female; Gingival Overgrowth; Glucocorticoids; Humans; Immunosuppressive Agents; Kidney Transplantation; Lip; Logistic Models; Male; Middle Aged; Mouth Breathing; Nifedipine; Prednisolone; Time Factors | 1998 |
A calcineurin inhibitor, FK506, blocks voltage-gated calcium channel-dependent LTP in the hippocampus.
Topics: Animals; Calcineurin Inhibitors; Calcium Channel Blockers; Calcium Channels; Cyclosporine; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Immunosuppressive Agents; Ion Channel Gating; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Nifedipine; Tacrolimus; Tetraethylammonium | 1998 |
Medication influencing the development of gingival overgrowth in renal transplant patients.
Topics: Cyclosporine; Gingiva; Gingival Hyperplasia; Gingivitis; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Longitudinal Studies; Nifedipine; Risk Factors; Waiting Lists | 1998 |
[Drug-induced gingival hyperplasia].
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Cyclosporine; Drug Therapy, Combination; Female; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Kidney Transplantation; Nifedipine | 1998 |
Re: Periodontal management of gingival overgrowth in the heart transplant patient: a case report (1997;68:1140-1146)
Topics: Adult; Azathioprine; Calcium Channel Blockers; Candidiasis, Oral; Chlorhexidine; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Spores, Fungal | 1998 |
Absence of a dose-response of cyclosporine levels to clinically used doses of diltiazem and verapamil.
Topics: Administration, Oral; Calcium Channel Blockers; Cyclosporine; Diltiazem; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Isradipine; Medical Records; Nifedipine; Radioimmunoassay; Retrospective Studies; Verapamil | 1999 |
Cyclosporine-induced coronary artery constriction--dissociation between thromboxane release and coronary vasospasm.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Cyclooxygenase Inhibitors; Cyclosporine; Endothelium, Vascular; Heart; Heart Rate; Immunosuppressive Agents; Male; Myocardial Contraction; Myocardium; Nifedipine; Nitric Oxide Donors; Nitroglycerin; Pharmaceutical Vehicles; Polyethylene Glycols; Prostanoic Acids; Rats; Rats, Wistar; Receptors, Thromboxane; Thromboxane B2; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Density of CD1a-labeled Langerhans' cells in normal human gingiva and in nifedipine- and immunosuppressive medication-induced gingival overgrowth.
Topics: Adult; Anti-Inflammatory Agents; Antigens, CD1; Azathioprine; Calcium Channel Blockers; Cell Count; Connective Tissue; Cyclosporine; Epithelial Attachment; Epithelium; Female; Gingiva; Gingival Overgrowth; Humans; Immunoenzyme Techniques; Immunosuppressive Agents; Kidney Transplantation; Langerhans Cells; Male; Nifedipine; Prednisolone | 1999 |
Continuous infusion cyclosporine and nifedipine to day +100 with short methotrexate and steroids as GVHD prophylaxis in unrelated donor transplants.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Calcium Channel Blockers; Cause of Death; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Graft vs Host Disease; Hematologic Neoplasms; Humans; Immunosuppressive Agents; Infant; Life Tables; Male; Methotrexate; Methylprednisolone; Middle Aged; Nifedipine; Survival Analysis; Transplantation, Homologous; Treatment Outcome; Wiskott-Aldrich Syndrome | 1999 |
Effectiveness of periodontal therapy in patients with drug-induced gingival overgrowth. Long-term results.
Topics: Adult; Age Factors; Calcium Channel Blockers; Cyclosporine; Dental Plaque Index; Dental Prophylaxis; Female; Follow-Up Studies; Gingival Hemorrhage; Gingival Overgrowth; Gingivectomy; Gingivitis; Humans; Immunosuppressive Agents; Incidence; Longitudinal Studies; Male; Middle Aged; Nifedipine; Periodontal Index; Quality of Life; Recurrence; Regression Analysis; Surgical Flaps | 1999 |
Regulation of gingival fibroblast interleukin-6 secretion by cyclosporine A.
Topics: Anticonvulsants; Bacteria; Calcium Channel Blockers; Cell Division; Cells, Cultured; Cyclosporine; Down-Regulation; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gingiva; Gingival Overgrowth; Humans; Immunosuppressive Agents; Interleukin-1; Interleukin-6; Nifedipine; Phenytoin; Tumor Necrosis Factor-alpha; Up-Regulation | 1999 |
New clinical index for drug-induced gingival overgrowth.
Topics: Adult; Calcium Channel Blockers; Cyclosporine; Female; Gingival Overgrowth; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Nifedipine; Severity of Illness Index | 1999 |
Relationship between gingival hyperplasia and class II histocompatibility antigens in renal transplant recipients.
Topics: Adult; Calcium Channel Blockers; Cyclosporine; Female; Gingival Hyperplasia; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine | 2000 |
Impact of cyclosporin A pharmacokinetics on the presence of side effects in pediatric renal transplantation.
Topics: Adolescent; Adult; Antihypertensive Agents; Child; Cyclosporine; Female; Gingival Hyperplasia; Hand; Humans; Hypertrichosis; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Postoperative Period; Tremor | 2000 |
The calcium channel blocker used with cyclosporin has an effect on gingival overgrowth.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Cyclosporine; Drug Therapy, Combination; Female; Gingival Overgrowth; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Multivariate Analysis; Nifedipine; Prevalence; Prognosis | 2000 |
Cocaine induces apoptosis in human coronary artery endothelial cells.
Topics: Apoptosis; Caspase Inhibitors; Cells, Cultured; Cocaine; Coronary Vessels; Cyclosporine; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Humans; Naloxone; Narcotic Antagonists; Nifedipine; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Effects of combined oral treatments with cyclosporine A and nifedipine or diltiazem on drug-induced gingival overgrowth in rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Body Weight; Calcium Channel Blockers; Cyclosporine; Diltiazem; Drug Combinations; Drug Interactions; Gingiva; Gingival Overgrowth; Growth; Immunosuppressive Agents; Male; Nifedipine; Rats; Rats, Inbred F344; Single-Blind Method | 2000 |
Calcium antagonists potentiate P-glycoprotein-independent anticancer drugs in chronic lymphocytic leukemia cells in vitro.
Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; B-Lymphocytes; Calcium; Calcium Channel Blockers; Calcium Signaling; Chlorambucil; Cisplatin; Cladribine; Cyclosporine; DNA Fragmentation; Doxorubicin; Drug Synergism; Female; Flow Cytometry; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Nifedipine; Prednisolone; Tumor Cells, Cultured; Verapamil; Vidarabine; Vincristine | 2000 |
Nifedipine prevents changes in nitric oxide synthase mRNA levels induced by cyclosporine.
Topics: Animals; Body Weight; Cyclosporine; Glomerular Filtration Rate; Glyceraldehyde-3-Phosphate Dehydrogenases; Isoenzymes; Kidney Cortex; Kidney Medulla; Liver; Liver Function Tests; Male; Nephrectomy; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organ Specificity; Rats; Rats, Wistar; RNA, Messenger | 2000 |
Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Body Weight; Calcium Channel Blockers; Creatinine; Cyclosporine; Dinoprostone; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Enzyme Inhibitors; Female; Immunoassay; Kidney; Nifedipine; Proteinuria; Rats; Rats, Wistar; Spectrophotometry; Thromboxane B2; Urine | 2000 |
N-methyl-D-aspartate receptor activation results in regulation of extracellular signal-regulated kinases by protein kinases and phosphatases in glutamate-induced neuronal apototic-like death.
Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclosporine; Dizocilpine Maleate; Egtazic Acid; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Nifedipine; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Macrophages and lymphocyte subpopulations in nifedipine- and cyclosporin A-associated human gingival overgrowth.
Topics: Adult; Antibodies, Monoclonal; Antigens, CD; Antigens, CD20; Antigens, Differentiation, Myelomonocytic; B-Lymphocytes; Calcium Channel Blockers; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Count; Connective Tissue; Cyclosporine; Epithelium; Female; Gingiva; Gingival Overgrowth; Heart Diseases; Humans; Immunoenzyme Techniques; Immunosuppressive Agents; Kidney Transplantation; Lymphocyte Count; Lymphocyte Subsets; Macrophages; Male; Nifedipine; Statistics as Topic; Statistics, Nonparametric | 2001 |
Mitotic activity of keratinocytes in nifedipine- and immunosuppressive medication-induced gingival overgrowth.
Topics: Adult; Aged; Azathioprine; Calcium Channel Blockers; Cell Count; Cyclosporine; Epithelial Cells; Epithelium; Female; Gingiva; Gingival Overgrowth; Glucocorticoids; Heart Diseases; Humans; Immunoenzyme Techniques; Immunosuppressive Agents; Keratinocytes; Ki-67 Antigen; Male; Middle Aged; Mitosis; Nifedipine; Organ Transplantation; Prednisolone; Statistics as Topic; Statistics, Nonparametric | 2001 |
P-Glycoprotein conformational changes detected by antibody competition.
Topics: 3T3 Cells; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Flow Cytometry; Humans; Mice; Nifedipine; Polysorbates; Protein Binding; Protein Conformation; Substrate Specificity; Tumor Cells, Cultured; Valinomycin; Verapamil; Vinblastine | 2001 |
Oral health in children undergoing liver transplantation.
Topics: Adolescent; Case-Control Studies; Chi-Square Distribution; Child; Child, Preschool; Cyclosporine; Dental Caries; Dental Plaque; Dental Plaque Index; DMF Index; Female; Follow-Up Studies; Gingival Overgrowth; Gingivitis; Humans; Immunosuppressive Agents; Liver Failure; Liver Transplantation; Male; Nifedipine; Periodontal Index; Prevalence; Reproducibility of Results; Socioeconomic Factors; Statistics as Topic; Statistics, Nonparametric; Tacrolimus; Tooth, Deciduous | 2000 |
Does nifedipine aggravate cyclosporin--induced gingival overgrowth? An experiment in rats.
Topics: Animals; Calcium Channel Blockers; Cyclosporine; Dental Enamel; Dentin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Gingiva; Gingival Overgrowth; Immunosuppressive Agents; Male; Nifedipine; Rats; Rats, Sprague-Dawley; Regression Analysis; Statistics as Topic; Tooth Root | 2001 |
Cyclosporin A-induced gingival overgrowth is unrelated to allograft function in renal transplant recipients.
Topics: Adolescent; Adult; Aged; Azathioprine; Calcium Channel Blockers; Child; Child, Preschool; Creatinine; Cyclosporine; Dental Plaque; Emulsions; Female; Gingival Hyperplasia; Gingivitis; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Nifedipine; Prednisolone; Regression Analysis; Risk Factors; Transplantation, Homologous | 2001 |
Connective tissue growth factor in drug-induced gingival overgrowth.
Topics: Adult; Antibodies; Anticonvulsants; Calcium Channel Blockers; Carrier Proteins; Coloring Agents; Connective Tissue; Connective Tissue Growth Factor; Cyclosporine; Endothelium, Vascular; Epithelium; Female; Fibroblasts; Fibrosis; Gingival Overgrowth; Growth Substances; Humans; Image Processing, Computer-Assisted; Immediate-Early Proteins; Immunoenzyme Techniques; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Leukocytes, Mononuclear; Male; Middle Aged; Mitogens; Neovascularization, Pathologic; Nifedipine; Phenytoin; Platelet Endothelial Cell Adhesion Molecule-1; Statistics, Nonparametric; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
The effect of an immunosuppressive therapy and its withdrawal on bone healing around titanium implants. A histometric study in rabbits.
Topics: Animals; Bone and Bones; Calcium Channel Blockers; Coloring Agents; Cyclosporine; Dental Implants; Dental Prosthesis Design; Drug Combinations; Follow-Up Studies; Immunosuppressive Agents; Injections, Subcutaneous; Nifedipine; Osseointegration; Pharmaceutical Vehicles; Rabbits; Random Allocation; Statistics as Topic; Statistics, Nonparametric; Tibia; Titanium; Weight Loss; Wound Healing | 2001 |
[No influence of propanolol, cyclosporine, adriamycin, and nifedipine on the in vitro labelling of erythrocytes].
Topics: Adult; Centrifugation; Cyclosporine; Doxorubicin; Edetic Acid; Erythrocytes; Humans; Hypochlorous Acid; Isotope Labeling; Nifedipine; Propranolol; Radiopharmaceuticals; Technetium; Tin Compounds | 2002 |
Morphological evaluation of combined effects of cyclosporin and nifedipine on gingival overgrowth in rats.
Topics: Analysis of Variance; Animals; Blood Vessels; Calcium Channel Blockers; Cyclosporine; Drug Synergism; Fibrillar Collagens; Fibroblasts; Gingiva; Gingival Overgrowth; Immunosuppressive Agents; Male; Nifedipine; Rats; Rats, Wistar | 2002 |
Characterization of berberine transport into Coptis japonica cells and the involvement of ABC protein.
Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Azides; Berberine; Biological Transport; Cells, Cultured; Cyclosporine; Genes, MDR; Hydrogen-Ion Concentration; Lithospermum; Macrolides; Nicotiana; Nifedipine; Quinidine; Ranunculaceae; Vacuoles; Vanadates | 2002 |
Molecular size distribution analysis of human gingival glycosaminoglycans in cyclosporin- and nifedipine-induced overgrowths.
Topics: Adolescent; Adult; Calcium Channel Blockers; Chondroitin Sulfates; Chromatography, Gel; Cyclosporine; Dermatan Sulfate; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Gingiva; Gingival Overgrowth; Glycosaminoglycans; Heparitin Sulfate; Humans; Hyaluronic Acid; Immunosuppressive Agents; Middle Aged; Molecular Structure; Molecular Weight; Nifedipine; Sepharose | 2003 |
The effect of cyclosporine with and without nifedipine on gingival overgrowth in renal transplant patients.
Topics: Adult; Age Factors; Calcium Channel Blockers; Cyclosporine; Dental Care for Chronically Ill; Dental Plaque Index; Drug Combinations; Female; Gingival Overgrowth; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Periodontal Index; Sex Factors; Statistics, Nonparametric | 2003 |
Combined effects of cyclosporin and nifedipine on gingival overgrowth in rats is not age dependent.
Topics: Age Factors; Analysis of Variance; Animals; Calcium Channel Blockers; Connective Tissue; Cyclosporine; Drug Combinations; Drug Synergism; Epithelium; Gingival Overgrowth; Immunosuppressive Agents; Male; Nifedipine; Rats; Rats, Wistar | 2003 |
Haemodynamic changes in human kidney allografts following administration of nifedipine: assessment with Doppler spectrum analysis.
Topics: Adult; Calcium Channel Blockers; Cyclosporine; Female; Hemodynamics; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Regional Blood Flow; Renal Circulation; Transplantation, Homologous; Ultrasonography, Doppler; Vascular Resistance | 1992 |
The effects of nifedipine on cyclosporine nephrotoxicity in rats.
Topics: Animals; Cyclosporine; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; Models, Animal; Nifedipine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; Vasodilator Agents | 1992 |
Influence of age on combined effects of cyclosporin and nifedipine on rat alveolar bone.
Topics: Administration, Oral; Aging; Alkaline Phosphatase; Alveolar Process; Animals; Bone Density; Bone Marrow; Calcium; Calcium Channel Blockers; Cyclosporine; Image Processing, Computer-Assisted; Immunosuppressive Agents; Injections, Subcutaneous; Male; Nifedipine; Rats; Rats, Wistar; Time Factors | 2004 |
Risk factors of gingival overgrowth in kidney transplant recipients treated with cyclosporine A.
Topics: Adult; Alleles; Amlodipine; Calcium Channel Blockers; Cyclosporine; Female; Gingival Overgrowth; HLA-DR2 Antigen; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Nifedipine; Risk Factors; Sex Factors | 2003 |
Ca2+ controls functional expression of the cardiac K+ transient outward current via the calcineurin pathway.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcineurin; Calcium; Calcium Channel Agonists; Calmodulin; Cells, Cultured; Chelating Agents; Culture Media, Serum-Free; Cyclosporine; Down-Regulation; Egtazic Acid; Electrophysiology; Kinetics; Models, Biological; Nifedipine; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Shal Potassium Channels; Signal Transduction; Tacrolimus; Temperature; Time Factors | 2004 |
Mast cell subpopulations in gingival overgrowth induced by immunosuppressive and nifedipine medication.
Topics: Adult; Aged; Case-Control Studies; Cell Count; Cyclosporine; Female; Gingiva; Gingival Overgrowth; Humans; Immunosuppressive Agents; Male; Mast Cells; Middle Aged; Nifedipine; Statistics, Nonparametric | 2004 |
Nifedipine attenuates changes in nitric oxide levels, renal oxidative stress, and nephrotoxicity induced by cyclosporine.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Cyclosporine; Disease Models, Animal; Immunohistochemistry; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Male; Nifedipine; Nitric Oxide; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Wistar; Reference Values; Risk Factors; Sensitivity and Specificity | 2005 |
Periodontal management of gingival overgrowth in a renal transplant patient: a case report.
Topics: Adult; Calcium Channel Blockers; Cyclosporine; Female; Gingival Overgrowth; Gingivectomy; Humans; Immunosuppressive Agents; Kidney Transplantation; Nifedipine | 2005 |
Synergism between nifedipine and cyclosporine A on the incorporation of [35S]sulfate into human gingival fibroblast cultures in vitro.
Topics: Analysis of Variance; Calcium Channel Blockers; Cells, Cultured; Cyclosporine; Drug Synergism; Fibroblasts; Gingiva; Gingival Overgrowth; Glycosaminoglycans; Humans; Immunosuppressive Agents; Interleukin-1; Male; Nifedipine; Statistics, Nonparametric; Sulfur Radioisotopes | 2006 |
Oral findings in children with liver transplants.
Topics: Adolescent; Biliary Atresia; Child; Child, Preschool; Cyclosporine; Dental Enamel Hypoplasia; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Incisor; Infant; Liver Transplantation; Nifedipine; Oral Health; Prospective Studies; Time Factors; Tooth Discoloration; Tooth Diseases; Tooth Eruption; Tooth, Deciduous; Vasodilator Agents | 1995 |
Immunohistochemical evaluation of Ki-67 expression and apoptosis in cyclosporin A-induced gingival overgrowth.
Topics: Adult; Analysis of Variance; Apoptosis; Calcium Channel Blockers; Case-Control Studies; Cell Proliferation; Cyclosporine; Female; Gingival Overgrowth; Humans; Immunohistochemistry; Immunosuppressive Agents; In Situ Nick-End Labeling; Ki-67 Antigen; Kidney Transplantation; Male; Mitosis; Nifedipine; Phenytoin; Statistics, Nonparametric | 2007 |
Expression of fibronectin-binding integrins in gingival epithelium in drug-induced gingival overgrowth.
Topics: Adult; Analysis of Variance; Antigens, Neoplasm; Calcium Channel Blockers; Cyclosporine; Drug Combinations; Female; Fibronectins; Fluorescent Antibody Technique; Gingiva; Gingival Overgrowth; Humans; Immunosuppressive Agents; Integrin alpha5beta1; Integrin beta1; Integrins; Keratinocytes; Male; Nifedipine; Statistics, Nonparametric; Up-Regulation | 2007 |
Nifedipine and cyclosporin affect fibroblast calcium and gingiva.
Topics: Animals; Calcium; Calcium Channel Blockers; Collagen; Cyclosporine; Fibroblasts; Gingiva; Gingival Overgrowth; Immunosuppressive Agents; Male; Microcirculation; Nifedipine; Random Allocation; Rats | 2007 |
[Cyclosporine-induced gingival hyperplasia: report of one case].
Topics: Biofilms; Calcium Channel Blockers; Cyclosporine; Gingiva; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Male; Middle Aged; Nifedipine; Recurrence; Severity of Illness Index | 2007 |
Apoptosis in gingival overgrowth tissues.
Topics: Anticonvulsants; Apoptosis; Calcium Channel Blockers; Case-Control Studies; Caspase 3; Cell Proliferation; Cyclosporine; Fibroblasts; Fibromatosis, Gingival; Forkhead Box Protein O1; Forkhead Transcription Factors; Gingival Overgrowth; Gingivitis; Humans; Immunosuppressive Agents; In Situ Nick-End Labeling; Nifedipine; Phenytoin; Proliferating Cell Nuclear Antigen | 2007 |
Gingival fibroblasts grown from cyclosporin-treated patients show a reduced production of matrix metalloproteinase-1 (MMP-1) compared with normal gingival fibroblasts, and cyclosporin down-regulates the production of MMP-1 stimulated by pro-inflammatory c
Topics: Calcium Channel Blockers; Case-Control Studies; Cells, Cultured; Cyclosporine; Down-Regulation; Fibroblasts; Gingiva; Gingival Overgrowth; Humans; Immunosuppressive Agents; Interleukin-1; Matrix Metalloproteinase 1; Nifedipine; Oncostatin M; Tissue Inhibitor of Metalloproteinase-1 | 2007 |
Orthodontic treatment of a patient with a renal transplant and drug-induced gingival overgrowth: a case report.
Topics: Adolescent; Antihypertensive Agents; Cyclosporine; Dental Care for Chronically Ill; Dental Enamel Hypoplasia; Female; Gingival Overgrowth; Humans; Immunosuppressive Agents; Kidney Transplantation; Malocclusion; Nifedipine; Orthodontics, Corrective | 2007 |
Effects of cyclosporin, phenytoin, and nifedipine on the synthesis and degradation of gingival collagen in tufted capuchin monkeys (Cebus apella): histochemical and MMP-1 and -2 and collagen I gene expression analyses.
Topics: Animals; Anticonvulsants; Azo Compounds; Biopsy; Calcium Channel Blockers; Cebus; Collagen; Collagen Type I; Collagen Type IV; Coloring Agents; Cyclosporine; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gingiva; Gingival Overgrowth; Gingivitis; Histocytochemistry; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Nifedipine; Phenytoin; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Case of the month: drug-induced hyperplasia.
Topics: Adult; Cyclosporine; Diagnosis, Differential; Female; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin | 2008 |
Effect of cyclosporine on drug transport and pharmacokinetics of nifedipine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cyclosporine; Drug Interactions; Male; Nifedipine; Rats; Rats, Wistar; Rhodamine 123 | 2009 |
Use of hydrophobins in formulation of water insoluble drugs for oral administration.
Topics: Administration, Oral; Animals; Biological Availability; Cyclosporine; Drug Compounding; Hydrophobic and Hydrophilic Interactions; Male; Nifedipine; Particle Size; Pharmaceutical Preparations; Rats; Rats, Wistar; Solubility; Solutions; Water | 2010 |
Loss of basement membrane integrity in human gingival overgrowth.
Topics: Adult; Analysis of Variance; Basement Membrane; Case-Control Studies; Cell Adhesion Molecules; Collagen Type IV; Cyclosporine; Epithelial-Mesenchymal Transition; Female; Gene Expression; Gingival Overgrowth; Humans; Kalinin; Male; Nifedipine; Phenytoin; Statistics, Nonparametric; Young Adult | 2011 |
HOCl causes necrotic cell death in human monocyte derived macrophages through calcium dependent calpain activation.
Topics: Calcimycin; Calcium; Calcium Channel Blockers; Calcium Ionophores; Calpain; Caspase 3; Cyclosporine; Dantrolene; Enzyme Inhibitors; Flunarizine; Humans; Hypochlorous Acid; Lysosomes; Macrophages; Membrane Potential, Mitochondrial; Muscle Relaxants, Central; Necrosis; Nifedipine; Verapamil | 2012 |
Combination of nifedipine and subtherapeutic dose of cyclosporin additively suppresses mononuclear cells activation of patients with rheumatoid arthritis and normal individuals via Ca(2+) -calcineurin-nuclear factor of activated T cells pathway.
Topics: Adult; Aged; Apoptosis; Arthritis, Rheumatoid; Calcineurin; Calcineurin Inhibitors; Calcium; Calcium Channel Blockers; Cyclosporine; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interferon-gamma; Interleukin-10; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; NFATC Transcription Factors; Nifedipine; Real-Time Polymerase Chain Reaction; Signal Transduction; T-Lymphocytes | 2012 |
Oral pathology quiz # 75. Case number 4. Systemic medication.
Topics: Anticonvulsants; Cyclosporine; Diagnosis, Differential; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Male; Middle Aged; Nifedipine; Phenytoin; Vasodilator Agents | 2012 |
Characterisation of the membrane transport of pilocarpine in cell suspension cultures of Pilocarpus microphyllus.
Topics: Biological Transport; Cell Culture Techniques; Coffea; Culture Media; Cyclosporine; Kinetics; Nifedipine; Pilocarpine; Pilocarpus; Piper; Plant Leaves; Plant Proteins; Vacuolar Proton-Translocating ATPases | 2015 |
Human in vivo regional intestinal permeability: quantitation using site-specific drug absorption data.
Topics: Budesonide; Colon; Cyclosporine; Fenofibrate; Humans; Intestinal Absorption; Intestinal Mucosa; Lisdexamfetamine Dimesylate; Metoprolol; Nifedipine; Pyrimidines; Ranitidine; Rivastigmine; Sumatriptan; Terfenadine; Theophylline | 2015 |
CYP4A/CYP2C modulation of the interaction of calcium channel blockers with cyclosporine on EDHF-mediated renal vasodilations in rats.
Topics: Animals; Biological Factors; Calcium Channel Blockers; Cyclosporine; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Drug Interactions; Gene Expression Regulation, Enzymologic; Immunosuppressive Agents; Kidney; Male; Nifedipine; Rats; Rats, Sprague-Dawley; Vasodilation; Verapamil | 2017 |
Molecular basis of the counteraction by calcium channel blockers of cyclosporine nephrotoxicity.
Topics: Animals; Biomarkers; Blood Urea Nitrogen; Calcium Channel Blockers; Collagen Type IV; Creatinine; Cyclosporine; Dual Oxidases; Fibrosis; Inflammation Mediators; Kidney; Kidney Diseases; Male; NADPH Oxidases; NF-kappa B; Nifedipine; Oxidative Stress; Proteinuria; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Transforming Growth Factor beta1; Verapamil | 2018 |
Topical application of phenytoin or nifedipine-loaded PLGA microspheres promotes periodontal regeneration in vivo.
Topics: Administration, Topical; Alveolar Bone Loss; Animals; Biomarkers; Cyclosporine; Drug Carriers; Gingival Recession; Immunohistochemistry; Male; Microspheres; Nifedipine; Phenytoin; Polyesters; Random Allocation; Rats; Rats, Sprague-Dawley; Single-Blind Method; X-Ray Microtomography | 2019 |
Effects of cyclosporin, nifedipine and phenytoin on gingival myofibroblast transdifferentiation in monkeys.
Topics: Actins; Animals; Apoptosis; Biopsy; Cell Proliferation; Cell Transdifferentiation; Cyclosporine; Genes, bcl-2; Gingiva; Gingival Overgrowth; Haplorhini; Immunohistochemistry; Ki-67 Antigen; Longitudinal Studies; Male; Myofibroblasts; Nifedipine; Phenytoin; Random Allocation | 2018 |