nifedipine has been researched along with cyclic gmp in 81 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (22.22) | 18.7374 |
| 1990's | 39 (48.15) | 18.2507 |
| 2000's | 20 (24.69) | 29.6817 |
| 2010's | 4 (4.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kobayashi, A; Ogawa, K | 1 |
| Akimoto, Y; Jino, H; Kurahashi, K; Usui, H | 1 |
| Becker, RH; Jablonka, B; Linz, W; Rosenkranz, G; Schölkens, BA; Wiemer, G | 1 |
| Chik, CL; Girard, M; Ho, AK; O'Brien, L | 1 |
| Huang, LJ; Huang, TF; Kuo, SC; Sun, SS; Teng, CM; Yu, SM | 1 |
| Daly, JW; Gusovsky, F; Schulick, A; Yasumoto, T | 1 |
| Epstein, M; Hayashi, K; Loutzenhiser, R | 1 |
| Assayag, E; Heisler, S; Labrie, F; Mehri, Y; Simard, J | 1 |
| Heisler, S | 1 |
| Yokoyama, M | 1 |
| Benishin, CG; Pang, PK; Zeng, YY | 1 |
| Imamura, N; Kurokawa, K; Nakajima, S; Ueda, M | 1 |
| Blay, J; Hollenberg, MD | 1 |
| Bkaily, G; Sperelakis, N | 1 |
| Hayaishi, O; Miwa, N; Sugino, H; Ueno, R | 1 |
| Hashimoto, H; Taira, N; Yanagisawa, T | 1 |
| Nargeot, J | 1 |
| Chik, CL; Ho, AK; Klein, DC | 2 |
| Nerbonne, JM | 1 |
| Miller, RC; Schoeffter, P | 1 |
| Klein, DC; Sugden, AL; Sugden, D | 1 |
| Carter, CJ; Noel, F; Scatton, B | 1 |
| Daugherty, A; Woodward, B | 1 |
| Baba, A; Gotoh, M; Hayata, K; Kitanaka, J; Matsuda, T; Takuma, K; Yoshikawa, T | 1 |
| Chik, CL; Ho, AK; Karpinski, E; Li, B; Liu, QY | 1 |
| Ko, FN; Lu, ST; Teng, CM; Wu, YC | 1 |
| Dreijer, AM; Kits, KS | 1 |
| Gibson, A; McFadzean, I; Tucker, JF; Wayman, C | 1 |
| Laippala, P; Manninen, A; Tuimala, R; Vapaatalo, H; Vuorinen, P | 1 |
| Miyajima, E; Miyata, N; Otomo, S; Tsuchida, K; Yamaura, H | 1 |
| Dawson, TM; Dawson, VL; Snyder, SH; Uhl, GR | 1 |
| Garfield, RE; Izumi, H; Yallampalli, C | 1 |
| Dai, LJ; Quamme, GA | 1 |
| Deitmer, P; Golenhofen, K; Noack, T | 1 |
| Miyata, N; Otomo, S; Takahashi, K; Tanaka, M; Tsuchida, K; Yamaura, H | 1 |
| Calvino, R; Di Stilo, A; Fruttero, R; Gasco, A; Gasco, AM; Sorba, G | 1 |
| Ko, FN; Lin, CH; Lu, ST; Teng, CM; Wu, YC | 1 |
| Ashikaga, T; Kishi, Y; Makita, T; Numano, F; Sakita, S; Watanabe, R; Watanabe, T | 1 |
| Grieve, A; Griffiths, R; Malcolm, C; Ritchie, L; Schousboe, A | 1 |
| Finer, NN; Patole, SK | 1 |
| Kume, H; Mikawa, K; Takagi, K | 1 |
| Barthó, L; Lefebvre, RA | 1 |
| Blanco, I; Bockaert, J; Lafon-Cazal, M; Rodriguez-Alvarez, J | 1 |
| Grider, JR; Jin, JG; Makhlouf, GM; Murthy, KS | 1 |
| Kubo, T; Taguchi, K; Ueda, M | 1 |
| Leone, RJ; Naim, KL; Scholz, PM; Weiss, HR | 1 |
| Higuchi, S; Nakasone, C; Noguchi, K; Shigenobu, K; Shijuku, T; Takahashi, K; Tanaka, H; Tanaka, Y | 1 |
| Chang, W; Chen, TH; Pratt, S; Shoback, D | 1 |
| Gong, GX; Scholz, PM; Tse, J; Weiss, HR; Yan, L | 2 |
| Boev, KK; Fusi, F; Petkov, GV; Sgaragli, GP; Valoti, M | 1 |
| Itoh, Y; Kimura, K; Oka, M; Ukai, Y | 1 |
| Chen, S; Liu, G; Yang, T | 1 |
| Frank, DU; Horstman, DJ; McCall, DA; Rich, GF | 1 |
| Aguilar, E; Pinilla, L; Tena-Sempere, M | 1 |
| Andric, SA; Koshimizu, T; Stojilkovic, SS; Tomić, M; Yuan, D; Zivadinovic, D | 1 |
| Fukuo, K; Morimoto, S; Niinobu, T; Ogihara, T; Suhara, T; Yang, J | 1 |
| Asakura, M; Asanuma, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Sakata, Y; Sanada, S; Takashima, S; Ueda, Y | 1 |
| Cocks, TM; Selemidis, S | 1 |
| Berkels, R; Hass, U; Klaus, W | 1 |
| Lovren, F; Triggle, C | 1 |
| Gerzanich, V; Simard, JM; West, GA; Zhang, F | 1 |
| Broderick, KE; Davies, SA; Dow, JA; Kean, L; MacPherson, MR; O'Connell, FC; Pollock, VP | 1 |
| Karlsson, JO; Lossius, K; Persson, AA; Støen, R | 1 |
| Kawamura, H; Puro, DG; Sakagami, K; Wu, DM | 1 |
| Paterson, WG; Zhang, Y | 1 |
| Kagota, S; Kunitomo, M; Nakamura, K; Tamashiro, A; Yamaguchi, Y | 1 |
| Furukawa, K; Kodzuka, G; Motomura, S; Niwa, M; Oshima, Y; Seya, K; Taniguchi, S | 1 |
| Fujita, T; Itoh, Y; Oka, M; Wada, M; Yamamoto, A | 1 |
| Channer, KS; English, KM; Jones, RD; Jones, TH; Morton, IE; Roberts, SA; Ruban, LN | 1 |
| Delogu, MR; Desole, MS; Esposito, G; Miele, E; Miele, M; Migheli, R; Mura, MP; Rocchitta, G; Serra, PA; Taras, MG | 1 |
| Brading, AF; Hashitani, H; Suzuki, H | 1 |
| Furukawa, K; Motomura, S; Narita, R; Seya, K; Yoshida, K | 1 |
| Andersson, KE; Arner, A; Ekman, M | 1 |
| Mishra, SK; Prakash, VR; Ross, GR; Sathishkumar, K | 1 |
| Mulè, F; Rotondo, A; Serio, R | 1 |
| Chen, ZW; Fan, L; Furnary, A; Grove, KL; He, GW; Huang, Y; Xiao, XQ; Yang, Q | 1 |
| Chen, C; Han, X; Zhao, Y; Zhu, Y | 1 |
| Dou, D; Gao, Y; Guo, Y; Liu, J; Xu, X; Ying, L; Yu, X | 1 |
| Blood, AB; Liu, T; Longo, LD; Power, GG; Schroeder, HJ; Terry, MH; Wilson, SM; Zhang, M | 1 |
3 review(s) available for nifedipine and cyclic gmp
| Article | Year |
|---|---|
[Mechanism of action of sympathetic and parasympathetic neuromediators at the level of the heart cell: use of photosensitive molecules].
Topics: Acetylcholine; Animals; Catecholamines; Cyclic AMP; Cyclic GMP; Electrophysiology; Heart; Humans; Kinetics; Myocardium; Neurotransmitter Agents; Nifedipine; Parasympathetic Nervous System; Photochemistry; Potassium; Receptors, Muscarinic; Sympathetic Nervous System | 1985 |
Design and application of photolabile intracellular probes.
Topics: Animals; Body Fluids; Cyclic AMP; Cyclic GMP; Fluorescent Dyes; Intracellular Fluid; Kinetics; Membrane Potentials; Microinjections; Nifedipine; Nucleotides, Cyclic; Photochemistry; Photolysis | 1986 |
Experimental and clinical effects of magnesium infusion in the treatment of neonatal pulmonary hypertension.
Topics: Animals; Blood Coagulation; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Disease Models, Animal; Humans; Hypertension, Pulmonary; Infant, Newborn; Infant, Newborn, Diseases; Lung; Magnesium Sulfate; Meconium Aspiration Syndrome; Nifedipine; Nitric Oxide Synthase; Pulmonary Circulation; Respiration, Artificial; Swine; Thromboxane-A Synthase; Vasodilator Agents | 1995 |
1 trial(s) available for nifedipine and cyclic gmp
| Article | Year |
|---|---|
[Effect of antihypertensive agents on plasma endothelin, nitric oxide and so on in essential hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cyclic GMP; Enalapril; Endothelins; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Nitric Oxide | 1997 |
77 other study(ies) available for nifedipine and cyclic gmp
| Article | Year |
|---|---|
Effects of coronary vasodilator on cyclic nucleotides. The concentrations of cyclic AMP and cyclic GMP in canine coronary artery and left ventricular muscle following the administration of various coronary vasodilators.
Topics: Amyl Nitrite; Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Diltiazem; Dipyridamole; Dogs; Heart Ventricles; Isosorbide Dinitrate; Myocardium; Nifedipine; Nitroglycerin; Papaverine; Radioimmunoassay; Vasodilator Agents | 1979 |
Nifedipine-resistant Ca(++)-induced contraction in tail artery of spontaneously hypertensive rats.
Topics: Animals; Arteries; Blood Pressure; Calcium; Cyclic GMP; Egtazic Acid; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin | 1992 |
Effects of converting enzyme inhibitors and the calcium antagonist nifedipine alone and in combination on precontracted isolated rabbit aortic rings.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Cyclic GMP; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Potassium Chloride; Rabbits; Vasodilator Agents | 1992 |
Intracellular pH on protein kinase C and ionomycin potentiation of isoproterenol-stimulated cyclic AMP and cyclic GMP production in rat pinealocytes.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Cyclic AMP; Cyclic GMP; Hydrogen-Ion Concentration; Ionomycin; Isoproterenol; Male; Nifedipine; Phorbol Esters; Pineal Gland; Propionates; Protein Kinase C; Rats; Rats, Sprague-Dawley | 1992 |
Vasorelaxation of rat thoracic aorta caused by two Ca(2+)-channel blockers, HA-22 and HA-23.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Caffeine; Calcium Channel Blockers; Cromakalim; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Male; Nifedipine; Pyrans; Pyrazoles; Pyrroles; Rats; Rats, Inbred Strains; Vasodilation; Verapamil | 1992 |
Effects of maitotoxin on atrial natriuretic factor-mediated accumulation of cyclic GMP in PC12 cells.
Topics: Atrial Natriuretic Factor; Calcium; Cyclic GMP; Dose-Response Relationship, Drug; Ionomycin; Marine Toxins; Nifedipine; Nitroprusside; Oxocins; Pheochromocytoma; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Determinants of renal actions of atrial natriuretic peptide. Lack of effect of atrial natriuretic peptide on pressure-induced vasoconstriction.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Kidney; Male; Nifedipine; Nitroprusside; Rats; Rats, Inbred Strains; Renal Circulation; Vascular Resistance; Vasoconstriction | 1990 |
Atrial natriuretic factor does not affect basal, forskolin- and CRF-stimulated adenylate cyclase activity, cAMP formation or ACTH secretion, but does stimulate cGMP synthesis in anterior pituitary.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Atrial Natriuretic Factor; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic GMP; Growth Hormone; Kinetics; Mice; Nifedipine; Pituitary Gland, Anterior; Potassium Chloride; Tetradecanoylphorbol Acetate | 1986 |
BAY-K-8644-stimulated cyclic GMP synthesis in mouse pituitary tumor cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenocorticotropic Hormone; Animals; Azides; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Isoproterenol; Mice; Nifedipine; Nitroprusside; Pituitary Neoplasms; Sodium Azide; Stimulation, Chemical; Verapamil | 1986 |
[The effect of pharmacological pretreatment on the long-term globally ischemic heart; lysosome, cyclic nucleotide and myocardial injury].
Topics: Animals; Aprotinin; Betamethasone; Coronary Disease; Creatine Kinase; Cyclic AMP; Cyclic GMP; Dogs; Heart Arrest, Induced; Isoenzymes; Lysosomes; Myocardium; Nifedipine; Perfusion; Ubiquinone | 1987 |
Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. I. Studies with fluoride.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine Vasopressin; Arteries; Bucladesine; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; GTP-Binding Proteins; In Vitro Techniques; Inositol Phosphates; Kinetics; Male; Muscle, Smooth, Vascular; Nifedipine; Potassium Chloride; Rats; Rats, Inbred Strains; Sodium Fluoride; Vasoconstriction; Verapamil | 1989 |
A study on the hypotensive mechanism of pinacidil: relationship between its vasodilating effect and intracellular Ca2+ levels.
Topics: Animals; Antihypertensive Agents; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; Hydralazine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Pinacidil; Rabbits; Sulfonamides; Trifluoperazine; Vasodilation | 1989 |
Epidermal growth factor stimulation of prostacyclin production by cultured aortic smooth muscle cells: requirement for increased cellular calcium levels.
Topics: 6-Ketoprostaglandin F1 alpha; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta; Arginine Vasopressin; Calcium; Calcium Channel Blockers; Calcium Chloride; Cell Line; Cyclic GMP; Epidermal Growth Factor; Gallic Acid; Kinetics; Muscle, Smooth, Vascular; Nifedipine; Tetradecanoylphorbol Acetate | 1989 |
Injection of guanosine 5'-cyclic monophosphate into heart cells blocks calcium slow channels.
Topics: Action Potentials; Animals; Calcium; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic GMP; Electric Stimulation; Ion Channels; Isoproterenol; Myocardium; Nifedipine; Tetrodotoxin | 1985 |
Prostaglandin induces Ca2+ influx and cyclic GMP formation in mouse neuroblastoma X rat glioma hybrid NG108-15 cells in culture.
Topics: Aminoquinolines; Animals; Calcium; Cyclic GMP; Diltiazem; Dinoprost; Dinoprostone; Fluorescent Dyes; Glioma; Hybrid Cells; Kinetics; Mice; Neuroblastoma; Nifedipine; Potassium; Prostaglandin D2; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Rats; Tumor Cells, Cultured; Verapamil | 1988 |
The negative inotropic effect of nicorandil is independent of cyclic GMP changes: a comparison with pinacidil and cromakalim in canine atrial muscle.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzopyrans; Cromakalim; Cyclic AMP; Cyclic GMP; Dogs; Female; Guanidines; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nifedipine; Pinacidil; Potassium Channels; Pyrroles; Tetraethylammonium Compounds; Vasodilator Agents | 1988 |
Alpha 1-adrenergic potentiation of vasoactive intestinal peptide stimulation of rat pinealocyte adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate: evidence for a role of calcium and protein kinase-C.
Topics: Adrenergic alpha-Agonists; Animals; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Nifedipine; Norepinephrine; Ouabain; Pineal Gland; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1988 |
Role of sodium-calcium exchange and effects of calcium entry blockers on endothelial-mediated responses in rat isolated aorta.
Topics: Amiloride; Animals; Aorta; Bepridil; Calcium; Calcium Channel Blockers; Choline; Cyclic GMP; Diltiazem; Endothelium; Female; Lithium; Muscle, Smooth, Vascular; Nicergoline; Nifedipine; Pyrrolidines; Rats; Rats, Inbred Strains; Reserpine; Sodium; Verapamil | 1986 |
Essential role of calcium influx in the adrenergic regulation of cAMP and cGMP in rat pinealocytes.
Topics: Animals; Calcimycin; Calcium; Cations; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Kinetics; Nifedipine; Norepinephrine; Ouabain; Pineal Gland; Rats; Rats, Inbred Strains | 1986 |
Ionic mechanisms implicated in the stimulation of cerebellar cyclic GMP levels by N-methyl-D-aspartate.
Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; Male; N-Methylaspartate; Nifedipine; Rats; Zinc | 1987 |
Protein kinase C is involved in adrenergic stimulation of pineal cGMP accumulation.
Topics: Animals; Calcimycin; Cyclic AMP; Cyclic GMP; Isoproterenol; Nifedipine; Ouabain; Pineal Gland; Potassium; Protein Kinase C; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1987 |
Calcium and calcium slow channel antagonists on cyclic nucleotide levels in the isolated rat heart.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Electric Stimulation; Ion Channels; Manganese; Myocardial Contraction; Myocardium; Nifedipine; Rats; Verapamil | 1981 |
Corticotropin-releasing factor stimulates Ca2+ influx in cultured rat astrocytes.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic GMP; Kinetics; Nifedipine; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
cGMP inhibits L-type Ca2+ channel currents through protein phosphorylation in rat pinealocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Isoquinolines; Male; Nifedipine; Nitroprusside; Norepinephrine; Patch-Clamp Techniques; Phosphorylation; Pineal Gland; Piperazines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sulfonamides; Thionucleotides | 1995 |
Ca(2+)-channel blockade in rat thoracic aorta by crychine isolated from Cryptocarya chinensis Hemsl.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds; Caffeine; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Dioxoles; Drug Interactions; Female; Male; Muscle Contraction; Nifedipine; Norepinephrine; Plant Extracts; Plants, Medicinal; Potassium; Rats; Rats, Wistar | 1993 |
Multiple second messenger routes enhance two high-voltage-activated calcium currents in molluscan neuroendocrine cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channels; Cyclic AMP; Cyclic GMP; Electrophysiology; Isoquinolines; Lymnaea; Neurosecretory Systems; Nifedipine; omega-Conotoxin GVIA; Peptides; Phosphorylation; Piperazines; Protein Kinase C; Second Messenger Systems; Thionucleotides; Verapamil | 1995 |
Variable potency of nitrergic-nitrovasodilator relaxations of the mouse anococcygeus against different forms of induced tone.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Cyclic GMP; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Nifedipine; Nitric Oxide; Nitroprusside; Platelet Aggregation Inhibitors; Potassium; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Vasoconstrictor Agents; Vasodilation | 1994 |
Atrial natriuretic peptide and cyclic guanosine-3'5'-monophosphate in hypertensive pregnancy and during nifedipine treatment.
Topics: Administration, Oral; Adult; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Female; Humans; Hypertension; Nifedipine; Pregnancy; Pregnancy Complications, Cardiovascular; Water-Electrolyte Balance | 1994 |
Role of cyclic GMP in inhibitory effects of CD-349 in isolated blood vessels.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Cyclic GMP; Dihydropyridines; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium; Rabbits | 1994 |
Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures.
Topics: Animals; Arginine; Calcium; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Dantrolene; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fetus; Glutamates; Glutamic Acid; Hemoglobins; HIV Envelope Protein gp120; HIV-1; Inositol Phosphates; Models, Neurological; Neurons; Neurotoxins; Nifedipine; Nitric Oxide; Nitroarginine; Quinoxalines; Rats | 1993 |
Gestational changes in L-arginine-induced relaxation of pregnant rat and human myometrial smooth muscle.
Topics: Animals; Arginine; Carbachol; Cyclic GMP; Female; Humans; In Vitro Techniques; Muscle, Smooth; Myometrium; Nifedipine; Potassium Chloride; Pregnancy; Pregnancy, Animal; Rats; Uterine Contraction | 1993 |
Atrial natriuretic peptide initiates Ca2+ transients in isolated renal cortical thick ascending limb cells.
Topics: Animals; Atrial Natriuretic Factor; Calcium; Calcium-Transporting ATPases; Cyclic GMP; In Vitro Techniques; Intracellular Membranes; Kidney Cortex; Loop of Henle; Manganese; Nifedipine; Osmolar Concentration; Swine; Terpenes; Thapsigargin | 1993 |
Inhibitory effects of cicletanine on smooth muscle in comparison to those of nifedipine and sodium nitroprusside.
Topics: Animals; Anti-Arrhythmia Agents; Cyclic GMP; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Norepinephrine; Papaverine; Pyridines; Rabbits; Rats | 1993 |
CD-832, a new dihydropyridine derivative with both nitrate-like and Ca2+ channel antagonist vasodilator activities.
Topics: Animals; Aorta, Thoracic; Brain Chemistry; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nifedipine; Nitrates; Rabbits; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
Pharmacochemistry of the furoxan ring: recent developments.
Topics: Animals; Blood Platelets; Calcium Channel Blockers; Cyclic GMP; Guinea Pigs; Heart Rate; Humans; In Vitro Techniques; Myocardial Contraction; Nifedipine; Oxadiazoles; Platelet Aggregation Inhibitors; Prazosin; Vasodilator Agents | 1993 |
The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma glaucescens.
Topics: Alkaloids; Animals; Benzopyrans; Calcium; Calmodulin; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Egtazic Acid; Epithelium; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nitroprusside; Phenanthrenes; Plants, Medicinal; Propranolol; Pyrroles; Theophylline; Trachea; Vasodilator Agents | 1993 |
Effect of nifedipine on cyclic GMP turnover in cultured coronary smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Cells, Cultured; Coronary Vessels; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Guanylate Cyclase; Hydrolysis; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Phosphodiesterase Inhibitors; Swine; Vasodilator Agents | 1995 |
NMDA receptor-mediated cGMP synthesis in primary cultures of mouse cerebellar granule cells appears to involve neuron-astrocyte communication with NO operating as the intercellular messenger.
Topics: Animals; Astrocytes; Calcimycin; Calcium; Calcium Channel Blockers; Cell Communication; Cells, Cultured; Cerebellum; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamate-Ammonia Ligase; Glutamic Acid; Hemoglobins; Kinetics; Magnesium; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Nifedipine; Nitric Oxide; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Verapamil | 1996 |
Effects of BKCa channels on the reduction of cytosolic Ca2+ in cGMP-induced relaxation of guinea-pig trachea.
Topics: Animals; Apamin; Atrial Natriuretic Factor; Calcium; Cyclic GMP; Cytosol; Extracellular Space; Glyburide; Guinea Pigs; Intracellular Fluid; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Scorpion Venoms; Trachea | 1997 |
Mechanism of nitric oxide-induced contraction in the rat isolated small intestine.
Topics: Animals; Apamin; Calcium; Cyclic GMP; In Vitro Techniques; Intestine, Small; Male; Methylene Blue; Muscle Contraction; Nifedipine; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Ryanodine | 1997 |
Different routes of Ca2+ influx in NMDA-mediated generation of nitric oxide and arachidonic acid.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arachidonic Acid; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Cyclic GMP; Fetus; Kinetics; Mice; N-Methylaspartate; Neurons; Nifedipine; Nitric Oxide; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Spider Venoms; Visual Cortex | 1997 |
Characterization of PACAP receptors and signaling pathways in rabbit gastric muscle cells.
Topics: Adenylate Cyclase Toxin; Alkaloids; Aminoquinolines; Animals; Calcium; Carbazoles; Cells, Cultured; Citrulline; Cyclic AMP; Cyclic GMP; Cytosol; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Indoles; Isoquinolines; Kinetics; Muscle Relaxation; Muscle, Smooth; Neuropeptides; Neurotransmitter Agents; Nifedipine; Nitric Oxide Synthase; Nitroarginine; Pertussis Toxin; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase Inhibitors; Rabbits; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Signal Transduction; Stomach; Sulfonamides; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1997 |
Effects of cAMP and cGMP on L-type calcium channel currents in rat mesenteric artery cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bucladesine; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Patch-Clamp Techniques; Rats; Rats, Wistar | 1997 |
Increased O2 consumption and positive inotropy caused by cyclic GMP reduction are not altered after L-type calcium channel blockade.
Topics: Aminoquinolines; Animals; Calcium Channel Blockers; Cardiotonic Agents; Cyclic GMP; Drug Evaluation, Preclinical; Enzyme Inhibitors; Guanylate Cyclase; Nifedipine; Oxidation-Reduction; Oxygen Consumption; Rabbits | 1998 |
Possible involvement of nitric oxide-cGMP pathway in the negative chronotropic effect of CD-832, a novel dihydropyridine derivative.
Topics: Animals; Calcium Channel Blockers; Cyclic GMP; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Molsidomine; Niacinamide; Nifedipine; Nitric Oxide | 1998 |
Regulation of extracellular calcium-activated cation currents by cAMP in parathyroid cells.
Topics: Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Kinetics; Membrane Potentials; Nifedipine; Parathyroid Glands; Patch-Clamp Techniques; Tetraethylammonium | 1998 |
Relationship between decreased function and O2 consumption caused by cyclic GMP in cardiac myocytes and L-type calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Colforsin; Cyclic GMP; Heart; Muscle Contraction; Myocardium; Nifedipine; Nitroprusside; Oxygen Consumption; Rabbits; Radioimmunoassay | 1998 |
Negative metabolic effects of cyclic GMP in quiescent cardiomyocytes are not related to L-type calcium channel activity.
Topics: Analysis of Variance; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cyclic GMP; Heart; Myocardium; Nifedipine; Nitroprusside; Oxygen Consumption; Rabbits; Radioimmunoassay | 1998 |
Myorelaxant activity of 2-t-butyl-4-methoxyphenol (BHA) in guinea pig gastric fundus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Antihypertensive Agents; Antioxidants; Barium; Butylated Hydroxyanisole; Calcium Channel Agonists; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Indoles; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Nifedipine; Nitroprusside; Tetraethylammonium; Vasodilator Agents | 1998 |
Blockade by NS-7, a neuroprotective compound, of both L-type and P/Q-type Ca2+ channels involving depolarization-stimulated nitric oxide synthase activity in primary neuronal culture.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Agatoxins; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Cells, Cultured; Cyclic GMP; Electrophysiology; Mice; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Potassium Chloride; Pyrimidines; Spider Venoms | 1999 |
Inhaled nitric oxide and nifedipine have similar effects on lung cGMP levels in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Inhalation; Animals; Bronchodilator Agents; Cyclic AMP; Cyclic GMP; Down-Regulation; Enzyme Inhibitors; Epoprostenol; Hypertension, Pulmonary; Hypoxia; Lung; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Poisons; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1999 |
Nitric oxide stimulates growth hormone secretion in vitro through a calcium- and cyclic guanosine monophosphate-independent mechanism.
Topics: Animals; Calcium; Calcium Channel Blockers; Cyclic GMP; Hemoglobins; Human Growth Hormone; Male; Nifedipine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; Thiosulfate Sulfurtransferase; Thiosulfates; Verapamil | 1999 |
Characterization of a plasma membrane calcium oscillator in rat pituitary somatotrophs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Cell Membrane; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Endothelin-1; Female; Gonadotropin-Releasing Hormone; Ion Channels; Ionomycin; Kinetics; Nifedipine; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thyrotropin-Releasing Hormone | 1999 |
Pranidipine enhances the action of nitric oxide released from endothelial cells.
Topics: Amlodipine; Animals; Aorta, Thoracic; Calcium Channel Blockers; Cells, Cultured; Coculture Techniques; Cyclic GMP; Dihydropyridines; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; Male; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Superoxide Dismutase | 2000 |
Nifedipine-induced coronary vasodilation in ischemic hearts is attributable to bradykinin- and NO-dependent mechanisms in dogs.
Topics: Animals; Bradykinin; Calcium Channel Blockers; Coronary Vessels; Cyclic GMP; Dogs; Heart Rate; Myocardial Ischemia; Nifedipine; Nitric Oxide; Systole; Vasodilation | 2000 |
Nitrergic relaxation of the mouse gastric fundus is mediated by cyclic GMP-dependent and ryanodine-sensitive mechanisms.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Caffeine; Calcium Channel Blockers; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxadiazoles; Quinoxalines; Ryanodine | 2000 |
The calcium antagonist nifedipine inhibits the uptake of acetylated LDL into endothelial cells.
Topics: Acetylation; Animals; Calcium Channel Blockers; Cells, Cultured; Cholesterol, LDL; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Inhibitors; Nifedipine; Nitric Oxide; Nitric Oxide Donors; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Swine | 2000 |
Nitric oxide and sodium nitroprusside-induced relaxation of the human umbilical artery.
Topics: Calcium Channels; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Humans; In Vitro Techniques; Nifedipine; Nitric Oxide; Nitroprusside; Oxadiazoles; Oxygen; Potassium; Potassium Channel Blockers; Potassium Channels; Quinoxalines; Receptors, Atrial Natriuretic Factor; Umbilical Arteries; Vasodilation; Vasodilator Agents | 2000 |
Chronic nicotine alters NO signaling of Ca(2+) channels in cerebral arterioles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arterioles; Barium; Calcium; Calcium Channels; Calcium Channels, L-Type; Cerebral Arteries; Cerebrovascular Circulation; Cyclic GMP; Dihydropyridines; Electric Stimulation; Female; Membrane Potentials; Muscle, Smooth, Vascular; Nicotine; Nifedipine; Nitric Oxide; Nitroprusside; Potassium Channels; Rats; Rats, Inbred WKY; Signal Transduction; Time Factors; Tyrphostins | 2001 |
Model organisms: new insights into ion channel and transporter function. L-type calcium channels regulate epithelial fluid transport in Drosophila melanogaster.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cyclic GMP; Drosophila melanogaster; Drosophila Proteins; Enzyme Inhibitors; Insect Proteins; Ion Channels; Kidney Tubules; Neuropeptides; Nifedipine; Oligopeptides; Pyrrolidonecarboxylic Acid; Signal Transduction; Thapsigargin; Verapamil | 2001 |
Relative significance of the nitric oxide (NO)/cGMP pathway and K+ channel activation in endothelium-dependent vasodilation in the femoral artery of developing piglets.
Topics: Acetylcholine; Animals; Animals, Newborn; Calcium Channel Blockers; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Femoral Artery; Male; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Potassium; Potassium Channels; Swine; Vasodilation; Vasodilator Agents | 2001 |
Nitric oxide/cGMP-induced inhibition of calcium and chloride currents in retinal pericytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Chlorides; Cyclic GMP; Enzyme Inhibitors; Ion Channels; Methylene Blue; Nifedipine; Nitric Oxide; Nitroprusside; Patch-Clamp Techniques; Pericytes; Rats; Retinal Vessels; Vasodilator Agents | 2001 |
Nitric oxide contracts longitudinal smooth muscle of opossum oesophagus via excitation-contraction coupling.
Topics: Anesthetics, Local; Animals; Calcium Channel Blockers; Cyclic GMP; Enzyme Inhibitors; Esophagus; Female; In Vitro Techniques; Isometric Contraction; Male; Microelectrodes; Muscle, Smooth; Nifedipine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Opossums; Oxadiazoles; Quinoxalines; Signal Transduction; Tetrodotoxin; Triazenes | 2001 |
High salt intake impairs vascular nitric oxide/cyclic guanosine monophosphate system in spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Blood Vessels; Body Weight; Calcium Channel Blockers; Cyclic GMP; Endothelium, Vascular; Heart Rate; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary | 2002 |
Endothelium-dependent vasodilatory effect of vitisin C, a novel plant oligostilbene from Vitis plants (Vitaceae), in rabbit aorta.
Topics: Animals; Aorta; Atropine; Benzofurans; Calcimycin; Calcium; Calcium Channel Blockers; Carbachol; Cells, Cultured; Cholinergic Agonists; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Ionophores; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase; Rabbits; Stilbenes; Vasodilator Agents; Vitis | 2003 |
Gabapentin blocks L-type and P/Q-type Ca2+ channels involved in depolarization-stimulated nitric oxide synthase activity in primary cultures of neurons from mouse cerebral cortex.
Topics: Acetates; Amines; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Mice; Molecular Sequence Data; Neurons; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; omega-Conotoxin GVIA; Potassium Chloride; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Testosterone inhibits the prostaglandin F2alpha-mediated increase in intracellular calcium in A7r5 aortic smooth muscle cells: evidence of an antagonistic action upon store-operated calcium channels.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Line; Chelating Agents; Colforsin; Cyclic AMP; Cyclic GMP; Dideoxynucleosides; Dinoprost; Flow Cytometry; Imidazoles; Indoles; Intracellular Fluid; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide Donors; Nitroprusside; Testosterone; Verapamil | 2003 |
Role of the nitric oxide/cyclic GMP pathway and ascorbic acid in 3-morpholinosydnonimine (SIN-1)-induced increases in dopamine secretion from PC12 cells. A microdialysis in vitro study.
Topics: Animals; Antioxidants; Ascorbic Acid; Calcium; Calcium Channel Blockers; Cyclic GMP; Dialysis; Dopamine; Drug Interactions; In Vitro Techniques; Molsidomine; Nifedipine; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; PC12 Cells; Potassium; Rats; Signal Transduction; Time Factors | 2003 |
Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder.
Topics: Action Potentials; Amides; Animals; Apamin; Boron Compounds; Calcium; Calcium Signaling; Carbachol; Charybdotoxin; Colforsin; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Fura-2; Guinea Pigs; Isotonic Contraction; Male; Mechanotransduction, Cellular; Microelectrodes; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyridines; Transducers; Urinary Bladder | 2004 |
Nifedipine enhances cGMP production through the activation of soluble guanylyl cyclase in rat ventricular papillary muscle.
Topics: Animals; Calcium Channel Blockers; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Heart Ventricles; In Vitro Techniques; Male; Nifedipine; Papillary Muscles; Rats; Rats, Wistar | 2005 |
Developmental regulation of nerve and receptor mediated contractions of mammalian urinary bladder smooth muscle.
Topics: Adenosine Triphosphate; Age Factors; Amides; Animals; Animals, Newborn; Carbachol; Cholinergic Agonists; Cholinergic Fibers; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Nifedipine; Pyridines; Receptors, Muscarinic; Scopolamine; Tetrodotoxin; Urinary Bladder; Vasodilator Agents | 2006 |
Relative contribution of intracellular and extracellular Ca2+ to alpha2-adrenoceptor-mediated contractions of ovine pulmonary artery.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Glyburide; Guanfacine; Indoles; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nucleotides, Cyclic; Pulmonary Artery; Receptors, Adrenergic, alpha-2; Sheep; Vasoconstriction; Vasodilator Agents | 2006 |
Gastric relaxation induced by apigenin and quercetin: analysis of the mechanism of action.
Topics: Animals; Apigenin; Calcium; Calcium Channel Blockers; Carbachol; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nifedipine; Potassium Chloride; Quercetin; Stomach | 2009 |
Dual actions of cilnidipine in human internal thoracic artery: inhibition of calcium channels and enhancement of endothelial nitric oxide synthase.
Topics: Aged; Blotting, Western; Calcium Channel Blockers; Calcium Channels; Cyclic GMP; Dihydropyridines; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Humans; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Nifedipine; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2011 |
Ghrelin reduces voltage-gated calcium currents in GH₃ cells via cyclic GMP pathways.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Calcium Channels, T-Type; Calcium Signaling; Cell Line; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Ghrelin; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Protein Kinase C; Protein Kinase Inhibitors; Rats; Receptors, Ghrelin; Second Messenger Systems; Single-Cell Analysis; Somatotrophs | 2011 |
Inhibition of phosphoinositide 3-kinase potentiates relaxation of porcine coronary arteries induced by nitroglycerin by decreasing phosphodiesterase type 5 activity.
Topics: Animals; Chromones; Coronary Vessels; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Enzyme Inhibitors; Milrinone; Models, Animal; Morpholines; Nifedipine; Nitroglycerin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Purinones; Signal Transduction; Swine; Vasodilation; Vasodilator Agents | 2012 |
S-nitrosothiols dilate the mesenteric artery more potently than the femoral artery by a cGMP and L-type calcium channel-dependent mechanism.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclic GMP; Cysteine; Diltiazem; Female; Femoral Artery; Fetus; Indazoles; Male; Mesenteric Arteries; Nifedipine; Oxadiazoles; Quinoxalines; S-Nitrosoglutathione; S-Nitrosothiols; Sheep; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2016 |