nifedipine has been researched along with clotrimazole in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 16 (55.17) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Asman, M; Berkenstam, A; Bertilsson, G; Blomquist, P; Heidrich, J; Jendeberg, L; Ohlsson, R; Postlind, H; Svensson, K; Sydow-Bäckman, M | 1 |
| Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Burk, O; Eichelbaum, M; Geick, A | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Jekerle, V; Piquette-Miller, M; Teng, S | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Pratim Roy, P; Roy, K | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Sen, S; Sinha, N | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Grissmer, S; Hanselmann, C | 1 |
| Fowler, SM; Friedberg, T; Pritchard, MP; Riley, RJ; Sutcliffe, MJ; Wolf, CR | 1 |
| Fanò, G; Guarnieri, S; Mariggiò, MA; Rathbone, MP | 1 |
| Marks, B; Raucy, J; Trubetskoy, O; Yueh, MF; Zielinski, T | 1 |
| Chen, IL; Chen, IS; Chiang, NN; Horng, CT; Jan, CR; Kuo, DH; Liang, WZ; Shieh, PC | 1 |
| Asuthkar, S; Cohen, A; Demirkhanyan, L; Tominaga, M; Uchida, K; Zakharian, E | 1 |
| Brown, CD; DiNunzio, J; Farrington, AM; Huang, C; Martin, GE; Small, J; Su, Y; Yang, F | 1 |
1 review(s) available for nifedipine and clotrimazole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
28 other study(ies) available for nifedipine and clotrimazole
| Article | Year |
|---|---|
Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction.
Topics: Amino Acid Sequence; Aryl Hydrocarbon Hydroxylases; Base Sequence; Caco-2 Cells; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA Primers; DNA, Complementary; Enzyme Induction; Humans; Molecular Sequence Data; Oxidoreductases, N-Demethylating; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Regulatory Sequences, Nucleic Acid; Signal Transduction; Transcriptional Activation | 1998 |
ElogPoct: a tool for lipophilicity determination in drug discovery.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents | 2000 |
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Dimerization; DNA; DNA Primers; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestines; Molecular Sequence Data; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Rifampin; Transcription Factors | 2001 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Induction of ABCC3 (MRP3) by pregnane X receptor activators.
Topics: Animals; Cell Line, Tumor; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Multidrug Resistance-Associated Proteins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger | 2003 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity | 2012 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Characterization of apamin-sensitive Ca(2+)-activated potassium channels in human leukaemic T lymphocytes.
Topics: Apamin; Barium; Calcium; Calcium Channel Blockers; Cations, Divalent; Cations, Monovalent; Cell Membrane Permeability; Clotrimazole; Diltiazem; Humans; Ionomycin; Jurkat Cells; Kinetics; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Potassium Channels; Scorpion Venoms; Strontium; Verapamil | 1996 |
Amino acid 305 determines catalytic center accessibility in CYP3A4.
Topics: Alanine; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Binding Sites; Catalysis; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Econazole; Erythromycin; Humans; Imidazoles; Ketoconazole; Kinetics; Miconazole; Mixed Function Oxygenases; Multienzyme Complexes; Mutation; Nifedipine; Oxidoreductases, N-Demethylating; Substrate Specificity; Testosterone | 2000 |
Cooperation in signal transduction of extracellular guanosine 5' triphosphate and nerve growth factor in neuronal differentiation of PC12 cells.
Topics: Animals; Barbiturates; Blotting, Western; Calcium; Calcium Channel Blockers; Cell Count; Cell Differentiation; Chelating Agents; Clotrimazole; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Extracellular Space; Fluorescent Antibody Technique; Fluorescent Dyes; Gallic Acid; Growth Inhibitors; Guanosine Triphosphate; Ionomycin; Ionophores; Isoxazoles; Membrane Potentials; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nerve Growth Factor; Neurites; Nifedipine; PC12 Cells; Pertussis Toxin; Pyridoxal Phosphate; Rats; Signal Transduction; Suramin; Time Factors; Triazines | 2004 |
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Clotrimazole; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Enzyme Induction; Genes, Reporter; Genes, Synthetic; Humans; Ketoconazole; Liver Neoplasms; Lovastatin; Luciferases; Mifepristone; Neoplasm Proteins; Nifedipine; Omeprazole; Paclitaxel; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Thiazolidinediones; Transcription, Genetic; Troglitazone; Troleandomycin | 2005 |
Effect of clotrimazole on cytosolic Ca(2+) rise and viability in HA59T human hepatoma cells.
Topics: Apoptosis; Calcium; Calcium Signaling; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Clotrimazole; Cytosol; Fura-2; Humans; Liver Neoplasms; Nifedipine; Protein Kinase C; Signal Transduction; Type C Phospholipases | 2013 |
Stimulation-dependent gating of TRPM3 channel in planar lipid bilayers.
Topics: Cell Line; Clotrimazole; HEK293 Cells; Hot Temperature; Humans; Hyperalgesia; Insulin-Secreting Cells; Ion Channel Gating; Lipid Bilayers; Nifedipine; Phosphatidylinositol 4,5-Diphosphate; Pregnenolone; TRPM Cation Channels | 2016 |
Probing the Molecular-Level Interactions in an Active Pharmaceutical Ingredient (API) - Polymer Dispersion and the Resulting Impact on Drug Product Formulation.
Topics: Clotrimazole; Drug Carriers; Drug Compounding; Drug Liberation; Elasticity; Hot Melt Extrusion Technology; Hot Temperature; Magnetic Resonance Spectroscopy; Molecular Conformation; Nifedipine; Pyrrolidines; Rheology; Structure-Activity Relationship; Triazoles; Vinyl Compounds; Viscosity | 2020 |