nifedipine has been researched along with clonidine in 163 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (38.04) | 18.7374 |
| 1990's | 74 (45.40) | 18.2507 |
| 2000's | 18 (11.04) | 29.6817 |
| 2010's | 9 (5.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Mallard, NJ; Marshall, RW; Sithers, AJ; Spriggs, TL | 1 |
| Chen, YM; Han, QD | 1 |
| Kigoshi, S; Muramatsu, I; Ohmura, T; Oshita, M | 1 |
| Candura, SM; Coccini, T; Costa, LG; Manzo, L; Marraccini, P; Rossi, A; Tonini, M | 1 |
| Done, C; Sharp, T; Silverstone, PH | 1 |
| Tabrizchi, R; Triggle, CR | 2 |
| Uza, G | 1 |
| Espinoza, M; Flores, R; Ortiz, S; Schnur, P; Vallejos, S; Wainwright, M | 1 |
| Adachi, H; Kodama, K; Ogawa, T; Ohhara, H | 1 |
| Attenburrow, MJ; Robson, P; Silverstone, PH | 1 |
| Antonucci, F; Favazza, A; Gropuzzo, M; Messa, P; Mioni, G; Motanaro, D | 1 |
| Schnur, P | 1 |
| Faber, JE; McGillivray-Anderson, KM | 1 |
| Brieva, C; Penna, M; Pinardi, G; Vinet, R | 1 |
| Mustafa, AA | 1 |
| Kigoshi, S; Muramatsu, I; Ohmura, T | 1 |
| Morrone, LA; Pimpinella, G; Romanelli, L; Valeri, P | 1 |
| Martinelli, B; Morrone, LA; Severini, C; Valeri, P | 1 |
| Kakishita, E; Sakamoto, K; Wakabayashi, I | 1 |
| Maggi, CA | 1 |
| Grammatté, T; Schentke, KU; Strohbach, C | 1 |
| Mitrovic, V; Patyna, W; Schlepper, M; von Bruchhausen, V | 1 |
| Babaian, AS; Dzhandzhapanian, AZ; Gurgenian, SV; Mikaelian, ES | 1 |
| Abzaid, A; de Castro, EG; Dondici Filho, J; Gomes, JC; Luz, NS | 1 |
| Hüting, J; Mitrovic, V; Patyna, W; Schlepper, M; von Bruchhausen, V | 1 |
| Han, C; Li, J; Minneman, KP | 1 |
| Hashimoto, S; Kigoshi, S; Muramatsu, I; Ohmura, T; Oshita, M | 1 |
| Bauman, JL; Hoon, TJ; Just, VL; Leikin, JB; Paloucek, FP; Schrader, BJ | 1 |
| Liepinja, DJ; Rudzite, VK; Silava, AK; Vitols, AV | 1 |
| Stojić, D; Terzić, MR | 1 |
| Angelova, I; Kundurdzhiev, A; Popiliev, I | 1 |
| Liepinia, DJ; Skarda, IJ; Skards, JV; Vitols, AV; Voita, DU | 1 |
| de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B | 1 |
| Brückner, S; Kleine, P; Meissner, E; von Bruchhausen, V | 1 |
| Kurahashi, K; Ohtsuka, M; Satake, N; Shibata, S | 1 |
| Kaijser, L; Lundberg, JM; Pernow, J | 1 |
| Grosser, KD; Späh, F | 1 |
| Hester, RK; Satake, N; Shibata, S | 1 |
| Klepzig, M; Motz, W; Strauer, BE | 1 |
| Deering, AH; Harron, DW; McMahon, M; Scott, M; Shanks, RG | 1 |
| Satoh, Y; Taniguchi, K | 1 |
| Bernardin, M; Chapuis, Y; Dorey, F; Fouchard, J; Louvel, A; Luton, JP | 1 |
| Adamson, P; Brammer, MJ; Campbell, IC; Mantzourides, T; Xiang, JZ | 1 |
| Deschamps de Paillette, E; Grimberg, D; Tarrade, T | 1 |
| Cerný, J; Dolezel, S; Dostál, M; Guba, P; Petrzilka, J; Sotolová, O; Urbánek, P; Vasků, A; Vasků, J | 1 |
| Cerný, J; Dostál, M; Gregor, Z; Guba, P; Rebícek, J; Sotolová, O; Urbánek, P; Vasků, A; Vasků, J | 1 |
| Fagan, TC | 1 |
| Distler, A; Fritschka, E; Hoyer, J; Kribben, A; Philipp, T; Rothschild, M; Thiede, HM | 1 |
| Cusolito, S; Donowitz, M; el Sabban, ME; Homaidan, FR; Sharp, WG; Weiland, GA; Wicks, J | 1 |
| Anno, T; Ito, M; Kodama, I; Satake, N; Shibata, S | 1 |
| Pedrinelli, R; Salvetti, A; Scapellato, L; Stornello, M; Valvo, E | 1 |
| McGrath, JC | 1 |
| Grabensee, B | 1 |
| Kannan, MS; Seip, AE | 1 |
| Flores, F; Hester, RK; Satake, N; Shibata, S; Ueda, S | 1 |
| Ferguson, RK; Vlasses, PH | 1 |
| Atkin, S; Brosch, F; Jaker, M; Schmid, G; Soto, M | 1 |
| Strauer, BE | 1 |
| de Jonge, A; Mathy, MJ; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B | 2 |
| Goldstein, DS; Haass, M; Kopin, IJ; Zukowska-Grojec, Z | 1 |
| Ferrari, G; Santoro, A; Zuccalà, A; Zucchelli, P | 1 |
| Demidiuk, VT; Mikunis, RI; Monastyrskiĭ, IuI; Pshelutskiĭ, FF; Serkova, VK | 1 |
| Bapna, JS; Rajasekaran, M; Ramaswamy, S | 1 |
| Hong, KW; Jung, HO | 1 |
| Chen, S; Guo, JZ; Zhao, GS | 1 |
| Bhadoria, DP; Bhadoria, P; Deswal, A; Malhotra, KK; Sharma, M; Srivastava, AK | 1 |
| Houston, MC | 1 |
| Burdick, JF; Keown, PA; Racusen, LC; Solez, K; Vaughn, WK | 1 |
| Feinfeld, DA; Frishman, WH; Sherman, D | 1 |
| Catapano, MS; Marx, JA | 1 |
| Magagna, A; Pedrinelli, R; Salvetti, A; Scapellato, L; Stornello, M | 1 |
| Akopian, LM; Ivleva, AIa; Kobaleva, ZhD; Krasnobaeva, GM; Moiseev, VS | 1 |
| Meese, RB; Ram, CV | 1 |
| Leier, CV; Magorien, RD; Ren, JH; Unverferth, DV | 1 |
| Docherty, JR; Hyland, L | 1 |
| Kaschube, M; Zetler, G | 1 |
| Lappe, RW; Saslow, BA; Wendt, RL | 1 |
| Carrier, GO; Scarborough, NL | 2 |
| Marxer, A; Schier, O | 1 |
| Shen, JQ | 1 |
| de Jonge, A; Kalkman, HO; Mathy, MJ; Thoolen, MJ; Timmermans, PB; van Meel, JC; van Zwieten, PA; Wilffert, B | 1 |
| Conradi, EC; Cowart, TD; Evans, MG; Hurwitz, G; Olanoff, LS | 1 |
| Docherty, JR; McGrath, JC | 1 |
| Bertel, O; Conen, D; Dubach, UC | 1 |
| Jarrott, B; Nayler, WG; Thompson, JE | 1 |
| Carver, LA; Lee, CH; Strosberg, AM | 1 |
| Ram, CV | 1 |
| Bertel, O; Conen, D; Dubach, UC; Lang, C; Müller, J; Radü, EW | 1 |
| Brandt, D | 1 |
| Abe, K; Chiba, S; Haruyama, T; Imai, Y; Irokawa, N; Ito, T; Miura, Y; Otsuka, Y; Saito, K; Sakurai, Y; Sato, M; Yasujima, M; Yoshinaga, K | 1 |
| Del Guercio, R; Gentile, S | 1 |
| Behbahani, NR; Dehpour, AR; Tajkhorshid, E | 1 |
| Nishimura, S; Sorimachi, M; Yamagami, K | 1 |
| Iwanov, V; Jiang, GC; Moulds, RF | 2 |
| Chueh, SC; Guh, JH; Ko, FN; Teng, CM | 1 |
| Hart, SD; Timmermans, PB; Wong, PC | 1 |
| Ambrosio, GB; Casiglia, E; Colangeli, G; Di Menza, G; Ginocchio, G; Mazza, A; Onesto, C; Pegoraro, L; Spolaore, P | 1 |
| Aston, N; Chess-Williams, R; Couldwell, C | 1 |
| Guh, JH; Ko, FN; Teng, CM | 1 |
| Bonechi, I; Galetta, F; Giusti, C; Prattichizzo, FA | 1 |
| Oriowo, MA | 1 |
| Desai, MK; Dikshit, RK; Mansuri, SM; Shah, UH | 1 |
| Gorman, AJ; Vargas, HM; Zhou, L | 1 |
| Borycz, J; Bugajski, AJ; Bugajski, J; Gadek-Michalska, A | 1 |
| Gales, MA | 1 |
| Neĭko, IeM; Orynchak, MA; Serediuk, NM | 1 |
| Hays, L; Houston, MC | 1 |
| Harris, RL; McCabe, J; Sacchetti, A; Torres, M | 1 |
| Lo, SJ; Shih, YL | 1 |
| Shi, CZ; Zhuang, LZ | 1 |
| Amico, MC; Morrone, LA; Romanelli, L; Valeri, P | 1 |
| Chapple, CR; Chess-Williams, R; Furukawa, K; Rosario, DJ; Smith, DJ; Uchiyama, T | 1 |
| Bakris, GL; Smith, A | 1 |
| Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA | 1 |
| Boura, AL; David, R; Leitch, IM; Read, MA; Walters, WA | 1 |
| Dyer, DC; Nair, R | 1 |
| Ishida, T; Ishii, R; Naruse, T; Tagawa, T | 1 |
| Ishida, T; Ishii, R; Namba, K; Naruse, T; Tagawa, T | 1 |
| Dyer, DC; Hu, XQ | 1 |
| Hattori, Y; Kanno, M; Nagashima, M; Tohse, N | 1 |
| Fant, JS; Fiser, RT; James, LP; Kearns, GL | 1 |
| Eliutin, DV; Mil'tsyn, AS; Sadchikov, DV | 1 |
| Kanonidis, I; Kokkas, B; Kotoula, M; Kouyoumtzis, A; Missopoulou, A; Myronidou, M; Papadopoulos, C; Paradelis, A; Sakadamis, G; Voulgaropoulos, C | 1 |
| Hattori, K; Makara, Y; Maruyama, K; Nagatomo, T; Ohnuki, T; Suzuki, M; Tsuchiya, M; Watanabe, K | 1 |
| Connolly, C; Docherty, JR; McCormick, PA | 1 |
| Artemiou, O; Bîrsan, T; Klepetko, W; Kranz, A; Mares, P; Taghavi, S; Zuckermann, A | 1 |
| Baltodano, NM; Cienki, J; Materson, BJ; Preston, RA | 1 |
| Avellar, MC; Megale, A; Porto, CS; Silva, MA | 1 |
| Boselli, C; Grana, E | 1 |
| Robles, NR | 1 |
| Epstein, M | 1 |
| Marik, PE; Varon, J | 1 |
| Nath, C; Srivastava, SK | 1 |
| Stiefelhagen, P | 1 |
| Avellar, MC; Caricati-Neto, A; Jurkiewicz, A; Jurkiewicz, NH; Reuter, HR; Verde, LF | 1 |
| Füessl, HS | 1 |
| Shen, FM; Su, DF; Wang, J; Wang, MW | 1 |
| Abbate, M; Ferlazzo, E; Granata, F; Mazzù, I; Musolino, R; Narbone, MC | 1 |
| Chu, CC; Lin, MT; Shieh, JP; Wang, JJ | 1 |
| Grishin, OV; Ruksin, VV | 1 |
| Al Dera, H; Brock, JA; Furness, JB; Habgood, MD | 1 |
| Homma, M; Kohda, Y; Matsumoto, S; Momo, K; Sasaki, T | 1 |
10 review(s) available for nifedipine and clonidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Primary hyperaldosteronism caused by unilateral macronodular hyperplasia].
Topics: Adrenal Gland Diseases; Adrenal Glands; Adult; Clonidine; Follow-Up Studies; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Male; Middle Aged; Nifedipine | 1989 |
The comparative effects of clonidine hydrochloride and nifedipine in the treatment of hypertensive crises.
Topics: Clonidine; Emergencies; Humans; Hypertension; Nifedipine | 1988 |
Innovative drug delivery systems in cardiovascular medicine: nifedipine-GITS and clonidine-TTS.
Topics: Administration, Cutaneous; Angina Pectoris; Clinical Trials as Topic; Clonidine; Delayed-Action Preparations; Humans; Hypertension; Nifedipine | 1987 |
Hypertensive cardiovascular emergencies.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Diazoxide; Diuretics; Eclampsia; Emergencies; Female; Humans; Hypertension; Hypertension, Malignant; Labetalol; Minoxidil; Nifedipine; Nitroprusside; Pregnancy; Pulmonary Edema; Trimethaphan | 1985 |
Antihypertensive agents 1969-1980.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Ergolines; Fusaric Acid; Guanidines; Humans; Hydralazine; Indoramin; Methyldopa; Minoxidil; Nifedipine; Piperazines; Prazosin; Prostaglandins | 1981 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Diazoxide; Eclampsia; Emergencies; Female; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Labetalol; Minoxidil; Nifedipine; Nitroprusside; Phentolamine; Prazosin; Pregnancy; Pulmonary Edema; Trimethaphan | 1984 |
Oral antihypertensives for hypertensive urgencies.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Female; Humans; Hypertension; Labetalol; Male; Nifedipine; Randomized Controlled Trials as Topic | 1994 |
Diagnosis and management of hypertensive emergencies.
Topics: Adrenergic alpha-Agonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aortic Dissection; Calcium Channel Blockers; Clonidine; Emergencies; Humans; Hypertension; Nifedipine; Nitroprusside; Pulmonary Edema | 1999 |
The diagnosis and management of hypertensive crises.
Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Clonidine; Diazoxide; Enalaprilat; Female; Fenoldopam; Humans; Hypertension; Labetalol; Nicardipine; Nifedipine; Nitroprusside; Phentolamine; Pre-Eclampsia; Pregnancy; Propanolamines; Trimethaphan | 2000 |
19 trial(s) available for nifedipine and clonidine
| Article | Year |
|---|---|
The calcium channel antagonist nifedipine causes confusion when used to treat opiate withdrawal in morphine-dependent patients.
Topics: Adult; Clonidine; Confusion; Double-Blind Method; Humans; Male; Methadone; Morphine Dependence; Nifedipine; Substance Withdrawal Syndrome | 1992 |
Peritoneal clearances in hypertensive CAPD patients after oral administration of clonidine, enalapril, and nifedipine.
Topics: Biological Transport; Clonidine; Enalapril; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nifedipine; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum | 1992 |
[The effect of various non-ulcer pharmaceuticals on nocturnal gastric pH in healthy subjects].
Topics: Adult; Chlorprothixene; Circadian Rhythm; Clonidine; Female; Gastric Juice; Humans; Hydrogen-Ion Concentration; Ketotifen; Male; Nifedipine; Pirenzepine; Single-Blind Method; Stimulation, Chemical | 1991 |
[Nifedipine-clonidine combination in essential hypertension. Hemodynamic and neurohumoral findings of the combination in comparison with the effect of the individual substances].
Topics: Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1991 |
[Acute reduction of blood pressure: comparative study of nifedipine and clonidine].
Topics: Adult; Aged; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Randomized Controlled Trials as Topic | 1991 |
Effects of clonidine and nifedipine on left ventricular hypertrophy and muscle mass in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Clonidine; Echocardiography; Female; Heart; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation | 1987 |
Treatment of hypertensive urgencies and emergencies with nitrendipine, nifedipine, and clonidine: effect on blood pressure and heart rate.
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Clonidine; Drug Therapy, Combination; Emergencies; Female; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Nifedipine; Nitrendipine | 1988 |
Effect of the combination of alinidine and other anti-anginal drugs on heart rate and blood pressure in healthy volunteers.
Topics: Adult; Angina Pectoris; Atenolol; Blood Pressure; Clonidine; Double-Blind Method; Drug Evaluation; Drug Interactions; Heart Rate; Humans; Male; Nifedipine; Nitroglycerin; Posture | 1989 |
[Cicletanine administered with other antihypertensive agents].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Nifedipine; Pyridines | 1989 |
Humoral and haemodynamic interactions between clonidine and nifedipine in human essential hypertension.
Topics: Clonidine; Drug Interactions; Hemodynamics; Humans; Hypertension; Nifedipine | 1985 |
Oral nifedipine vs oral clonidine in the treatment of urgent hypertension.
Topics: Administration, Oral; Adult; Aged; Clonidine; Double-Blind Method; Emergencies; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Random Allocation | 1989 |
Pathogenesis of hypertension in hemodialysis patients: a pharmacological study.
Topics: Adult; Aged; Blood Pressure; Captopril; Clonidine; Humans; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Renal Dialysis; Renin | 1988 |
[Use of foridon in the treatment of arterial hypertension and hypertension of the lesser circulation].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Synergism; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Male; Middle Aged; Nifedipine | 1988 |
Innovative drug delivery systems in cardiovascular medicine: nifedipine-GITS and clonidine-TTS.
Topics: Administration, Cutaneous; Angina Pectoris; Clinical Trials as Topic; Clonidine; Delayed-Action Preparations; Humans; Hypertension; Nifedipine | 1987 |
Nifedipine in hypertensive emergencies.
Topics: Adult; Aged; Blood Pressure; Cerebrovascular Circulation; Clinical Trials as Topic; Clonidine; Emergencies; Heart Rate; Humans; Hypertension; Middle Aged; Nifedipine; Pyridines; Random Allocation | 1983 |
[Nifedipine and essential arterial hypertension refractory to hypotensive therapy: results of a preliminary double-blind study].
Topics: Adult; Aged; Chlorthalidone; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyridines; Reserpine | 1981 |
Effect of two different therapeutic approaches on total and cardiovascular mortality in a Cardiovascular Study in the Elderly (CASTEL).
Topics: Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Heart Diseases; Humans; Hypertension; Italy; Male; Nifedipine; Prospective Studies; Survival Analysis | 1994 |
Transdermal clonidine as an adjunct to nifedipine-GITS therapy in patients with mild-to-moderate hypertension.
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Chemotherapy, Adjuvant; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Patient Compliance; Prospective Studies; Time Factors | 1993 |
Effects of sodium intake on albumin excretion in patients with diabetic nephropathy treated with long-acting calcium antagonists.
Topics: Aged; Albuminuria; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Cross-Over Studies; Diabetic Nephropathies; Diltiazem; Female; Humans; Male; Middle Aged; Nifedipine; Prospective Studies; Sodium, Dietary | 1996 |
135 other study(ies) available for nifedipine and clonidine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Separation of putative alpha 1A- and alpha 1B-adrenoceptor mediated components in the tension response of the rat vas deferens to electrical field stimulation.
Topics: Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Suramin; Vas Deferens | 1992 |
[Alpha adrenoceptor subtypes in smooth muscles of rat pulmonary artery].
Topics: Animals; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Prazosin; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1992 |
Identification of alpha 1-adrenoceptor subtypes in the rat vas deferens: binding and functional studies.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Electric Stimulation; Epididymis; In Vitro Techniques; Kinetics; Male; Muscle, Smooth; Nifedipine; Norepinephrine; Oxathiins; Prazosin; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Vas Deferens | 1992 |
Calcium entry blockade as a mechanism for chlordimeform-induced inhibition of motor activity in the isolated guinea-pig ileum.
Topics: Adrenergic alpha-Antagonists; Animals; Chlorphenamidine; Clonidine; Dioxanes; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Idazoxan; Ileum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Peristalsis | 1992 |
Clonidine but not nifedipine prevents the release of noradrenaline during naloxone-precipitated opiate withdrawal: an in vivo microdialysis study in the rat.
Topics: Animals; Behavior, Animal; Clonidine; Male; Microdialysis; Morphine Dependence; Naloxone; Nifedipine; Norepinephrine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Weight Loss | 1992 |
The interrelationship between the effects of captopril and nifedipine on pressor responses elicited by selective alpha-adrenoceptor agonists in the pithed rat preparation.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Captopril; Clonidine; Decerebrate State; Imidazoles; Male; Nifedipine; Rats; Rats, Inbred Strains | 1992 |
Hypotensive drugs and the cellular energetic potential.
Topics: Antihypertensive Agents; Clonidine; Humans; Hypertension; Nifedipine; Phosphates; Propranolol; Water-Electrolyte Balance | 1992 |
Blocking naloxone-precipitated withdrawal in rats and hamsters.
Topics: Animals; Behavior, Animal; Clonidine; Cricetinae; Drug Implants; Mesocricetus; Morphine Dependence; Naloxone; Nifedipine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Verapamil; Yawning | 1992 |
Inhibitory effect of a novel antianginal agent, E4080, on ST segment elevation induced by vasopressin in anesthetized guinea pigs.
Topics: Anesthesia; Animals; Benzopyrans; Cardiovascular Agents; Catechols; Clonidine; Coronary Vessels; Cromakalim; Electrocardiography; Guinea Pigs; Heart Rate; Imidazoles; In Vitro Techniques; Isosorbide Dinitrate; Male; Nifedipine; Pyrroles; Vasodilator Agents; Vasopressins | 1992 |
Morphine withdrawal in the hamster.
Topics: Animals; Clonidine; Cricetinae; Morphine; Naloxone; Nifedipine; Stereotyped Behavior; Substance Withdrawal Syndrome; Verapamil | 1992 |
Effect of reduced blood flow on alpha 1- and alpha 2-adrenoceptor constriction of rat skeletal muscle microvessels.
Topics: Acidosis; Animals; Clonidine; Male; Microcirculation; Muscles; Nifedipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regional Blood Flow; Vasoconstriction | 1991 |
Influence of extracellular Ca2+ on the modulation of alpha-adrenergic-induced contractions in rat aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Clonidine; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phenylephrine; Rats; Receptors, Adrenergic, alpha | 1991 |
Rapid desensitization of central beta-adrenoceptors in rat after subacute treatment with imipramine and calcium entry blockers.
Topics: 1-Propanol; Animals; Calcium Channel Blockers; Clonidine; Diltiazem; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drinking Behavior; Fenclonine; Imipramine; Isoproterenol; Ketanserin; Nicardipine; Nifedipine; Oxidopamine; Rats; Receptors, Adrenergic, beta; Verapamil | 1991 |
Effects of staurosporine on the pressor responses to alpha-adrenoceptor agonists in pithed rats: a comparison with nifedipine.
Topics: Adrenergic alpha-Agonists; Alkaloids; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate State; Imidazoles; Male; Muscle, Smooth, Vascular; Nifedipine; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine | 1991 |
Subtypes of alpha 1-adrenoceptors involved in noradrenaline-induced contractions of rat thoracic aorta and dog carotid artery.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Carotid Arteries; Clonidine; Dogs; Electrophysiology; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Some pharmacological characteristics of the guinea pig ileum opioid system activated by cholecystokinin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Cholecystokinin; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Receptors, Opioid; Yohimbine | 1990 |
Reproducible withdrawal contractions of isolated guinea-pig ileum after brief morphine exposure: effects of clonidine and nifedipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Substance Withdrawal Syndrome; Yohimbine | 1990 |
Potentiating effect of daunorubicin on vasocontractile responses to KCl and BAY K 8644 in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Clonidine; Daunorubicin; Drug Synergism; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains | 1990 |
Omega conotoxin and prejunctional modulation of the biphasic response of the rat isolated urinary bladder to single pulse electrical field stimulation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Atropine; Calcium Channel Blockers; Calcium Channels; Clonidine; Drug Interactions; Drug Synergism; Electric Stimulation; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Physostigmine; Rats; Rats, Inbred Strains; Urinary Bladder | 1991 |
Efficacy of intravenous verapamil in arterial hypertension refractory to three-step antihypertensive therapy.
Topics: Adult; Antihypertensive Agents; Clonidine; Echocardiography; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Infusions, Intravenous; Male; Methyldopa; Middle Aged; Nifedipine; Ventricular Function, Left; Verapamil | 1991 |
Interactions of clonidine and nifedipine in moderately severe hypertensive patients.
Topics: Blood Pressure; Clonidine; Delayed-Action Preparations; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1991 |
Subtypes of alpha 1-adrenoceptors in rat blood vessels.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Clonidine; Dioxanes; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Artery | 1990 |
Pharmacological subclassification of alpha 1-adrenoceptors in vascular smooth muscle.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Blood Vessels; Clonidine; Dioxanes; Dogs; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phentolamine; Prazosin; Rabbits; Rats; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine | 1990 |
Evaluation of drug therapy for treatment of hypertensive urgencies in the emergency department.
Topics: Adolescent; Adult; Aged; Blood Pressure; Clonidine; Drug Therapy; Emergency Service, Hospital; Evaluation Studies as Topic; Female; Hospitals, University; Humans; Hypertension; Illinois; Male; Middle Aged; Nifedipine; Patient Compliance; Retrospective Studies; Risk Factors | 1991 |
Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Volume; Cardiomegaly; Clonidine; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Kynurenine; Male; Middle Aged; Nifedipine; Propranolol; Tryptophan | 1990 |
Differentiation of alpha adrenoceptors mediating increase of oxygen consumption in rat submandibular salivary gland slices.
Topics: Acetylcholine; Animals; Calcimycin; Calcium; Clonidine; Epinephrine; Female; Male; Nifedipine; Norepinephrine; Organ Culture Techniques; Ouabain; Oxygen Consumption; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Submandibular Gland | 1990 |
[Hypokalemia caused by nifedipine].
Topics: Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Hypokalemia; Nifedipine | 1990 |
Haemodynamic resistance of forearm vessels during prolonged drug treatment of essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clonidine; Drug Therapy, Combination; Forearm; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Muscle, Smooth, Vascular; Nifedipine; Propranolol; Vascular Resistance | 1990 |
Calcium dependency of vasoconstriction mediated by alpha 1- and alpha 2-adrenoceptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Azepines; Blood Pressure; Calcium; Calcium Channel Blockers; Clonidine; Imidazoles; Ion Channels; Nifedipine; Rats; Receptors, Adrenergic, alpha; Regional Blood Flow; Structure-Activity Relationship; Vasoconstriction | 1985 |
The vasoinhibitory action of FR 46171, a new pyridine alcohol antianginal agent, on isolated rabbit vascular smooth muscles.
Topics: Angina Pectoris; Animals; Aorta, Thoracic; beta-Cyclodextrins; Clonidine; Cyclodextrins; Dextrins; Egtazic Acid; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Norepinephrine; Phenoxybenzamine; Potassium Chloride; Pyridines; Rabbits; Starch | 1988 |
Alpha-adrenoceptor influence on plasma levels of neuropeptide Y-like immunoreactivity and catecholamines during rest and sympathoadrenal activation in humans.
Topics: Adrenal Glands; Adult; Catecholamines; Clonidine; Exercise; Humans; Male; Neuropeptide Y; Nifedipine; Norepinephrine; Phentolamine; Receptors, Adrenergic, alpha; Rest; Sympathetic Nervous System | 1988 |
Differential inhibitory effects of nitroglycerin on contractile responses to the alpha-adrenoceptor agonists, methoxamine and clonidine, in rabbit aorta.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Radioisotopes; Clonidine; Egtazic Acid; In Vitro Techniques; Lanthanum; Male; Methoxamine; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Phenoxybenzamine; Potassium; Prazosin; Rabbits; Yohimbine | 1989 |
Regression of cardiac hypertrophy: experimental and clinical results.
Topics: Animals; Cardiomegaly; Clonidine; Enalapril; Humans; Hypertension; Nifedipine; Prazosin; Rats; Rats, Inbred SHR | 1987 |
[Update in drug delivery system in the field of cardiovascular system].
Topics: Angina Pectoris; Clonidine; Delayed-Action Preparations; Dosage Forms; Humans; Nifedipine; Nitroglycerin | 1989 |
Presynaptic alpha 2-adrenoceptor and kappa-opiate receptor occupancy promotes closure of neuronal (N-type) calcium channels.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzofurans; Calcium; Calcium Channels; Clonidine; Dioxanes; Fura-2; Idazoxan; In Vitro Techniques; Male; Mollusk Venoms; Naloxone; Neurons; Nifedipine; omega-Conotoxin GVIA; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, kappa; Synapses; Synaptosomes | 1989 |
Therapy of venous hypertension in calves with total artificial heart (TAH).
Topics: Animals; Antihypertensive Agents; Captopril; Cardiac Pacing, Artificial; Cattle; Central Venous Pressure; Clonidine; Heart, Artificial; Hypertension; Liver Function Tests; Methyldopa; Nifedipine; Postoperative Complications; Prazosin | 1989 |
[Therapy of venous hypertension in animals with an artificial heart and long-term survival].
Topics: Animals; Antihypertensive Agents; Captopril; Cattle; Clonidine; Diltiazem; Heart, Artificial; Methyldopa; Nifedipine; Prazosin; Venous Pressure | 1989 |
Acute reduction of blood pressure in asymptomatic patients with severe hypertension. An idea whose time has come--and gone.
Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clonidine; Drug Administration Schedule; Humans; Hypertension; Nifedipine | 1989 |
Regulation of alpha 2-adrenoceptor density in normotensive and hypertensive man.
Topics: Adenylyl Cyclases; Blood Platelets; Clonidine; Furosemide; Humans; Hypertension; Male; Nifedipine; Norepinephrine; Receptors, Adrenergic, alpha | 1987 |
Ca2+ channel blockers interact with alpha 2-adrenergic receptors in rabbit ileum.
Topics: Animals; Calcium Channel Blockers; Clonidine; Diltiazem; Egtazic Acid; Electrolytes; Ileum; In Vitro Techniques; Intestinal Mucosa; Kinetics; Male; Membrane Potentials; Nifedipine; Rabbits; Receptors, Adrenergic, alpha; Verapamil; Yohimbine | 1988 |
Inhibitory effects of nitroglycerin on contractile responses to methoxamine and clonidine in isolated rabbit renal and femoral arteries.
Topics: Animals; Calcium; Calcium Channels; Clonidine; Femoral Artery; In Vitro Techniques; Male; Methoxamine; Nifedipine; Nitroglycerin; Phenoxybenzamine; Potassium; Rabbits; Renal Artery; Vasodilation | 1988 |
alpha-Adrenoceptor agonists and the Ca2+-dependence of smooth muscle contraction: evidence for subtypes of receptors or for agonist-dependent differences in the agonist-receptor interaction?
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Clonidine; Ethanolamines; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Xylazine | 1985 |
[Therapy of the hypertensive crisis].
Topics: Administration, Oral; Adrenergic beta-Antagonists; Calcium Channel Blockers; Clonidine; Dihydralazine; Female; Humans; Hypertension; Magnesium Sulfate; Male; Nifedipine; Phentolamine; Pheochromocytoma; Pre-Eclampsia; Pregnancy | 1985 |
Mechanisms of alpha-adrenoceptor mediated contractions of rat mesenteric artery.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Clonidine; In Vitro Techniques; Kinetics; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction; Verapamil | 1986 |
Effect of nicorandil, N-(2-hydroxyethyl)nicotinamide nitrate, a new anti-anginal agent, on contractile responses to alpha-1- and alpha-2-adrenoceptor agonists in isolated rabbit aorta.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Azepines; Clonidine; Male; Methoxamine; Niacinamide; Nicorandil; Nifedipine; Rabbits; Vasodilation | 1986 |
How urgent is 'urgent' hypertension?
Topics: Clonidine; Emergencies; Hospitalization; Humans; Hypertension; Nifedipine | 1989 |
[Progression and regression of heart hypertrophy in arterial hypertension: pathophysiology and clinical aspects].
Topics: Blood Pressure; Cardiac Volume; Cardiomegaly; Cardiomyopathy, Hypertrophic; Clonidine; Coronary Circulation; Heart Failure; Heart Ventricles; Humans; Hypertension; Nifedipine; Prazosin; Prognosis; Sympathetic Nervous System; Vascular Resistance | 1985 |
Effects of the irreversible alpha-adrenoceptor antagonists phenoxybenzamine and benextramine on the effectiveness of nifedipine in inhibiting alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in pithed rats.
Topics: Animals; Azepines; Clonidine; Cystamine; Decerebrate State; Diastole; Dose-Response Relationship, Drug; Imidazoles; Male; Nifedipine; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction | 1985 |
Differential inhibition of alpha adrenoceptor-mediated pressor responses by rat atrial natriuretic peptide in the pithed rat.
Topics: Adrenergic alpha-Antagonists; Animals; Atrial Natriuretic Factor; Blood Pressure; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Male; Nifedipine; Nitroprusside; Phenylephrine; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Role of calcium in prolactin analgesia.
Topics: Analgesics; Animals; Calcium; Calcium Chloride; Clonidine; Male; Mice; Morphine; Nifedipine; Prolactin; Thyrotropin-Releasing Hormone | 1986 |
Characterization of inhibition by nifedipine and nitroprusside of the pressor responses to alpha 1-adrenoceptor agonists cirazoline and Sgd 101/75 in pithed rats.
Topics: Animals; Blood Pressure; Clonidine; Ferricyanides; Imidazoles; Male; Nifedipine; Nitroprusside; Rats; Rats, Inbred Strains; Vasoconstriction | 1988 |
[The relation of hypotensive effects of nifedipine and clonidine and changes in platelet-free calcium and serum-free calcium in essential hypertension].
Topics: Adult; Aged; Blood Platelets; Calcium; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1988 |
Safe use of clonidine, nifedipine and vitamin K in hepatic porphyria.
Topics: Adult; Clonidine; Humans; Hypertension; Liver Diseases; Male; Nifedipine; Porphyrias; Vitamin K | 1988 |
The influence of antihypertensive drug therapy on renal transplant function and outcome.
Topics: Antihypertensive Agents; Clonidine; Creatinine; Cyclosporins; Graft Rejection; Humans; Kidney; Kidney Transplantation; Metoprolol; Nifedipine; Propranolol | 1988 |
Management of urgent hypertension: a comparison of oral treatment regimens in the emergency department.
Topics: Administration, Oral; Antihypertensive Agents; Captopril; Clonidine; Drug Administration Schedule; Emergency Service, Hospital; Hemodynamics; Humans; Hypertension; Labetalol; Minoxidil; Nifedipine; Prazosin | 1986 |
Calcium antagonists: interactions in hypertension.
Topics: Adult; Blood Pressure; Clonidine; Drug Interactions; Female; Humans; Hypertension; Indomethacin; Male; Middle Aged; Nifedipine; Renin | 1986 |
[Pharmacodynamic interaction of clonidine and nifedipine].
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Clonidine; Diastole; Drug Interactions; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Systole; Vascular Resistance | 1987 |
Drugs for hypertensive emergencies.
Topics: Administration, Oral; Captopril; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hypertension; Infusions, Parenteral; Labetalol; Nifedipine; Nitroprusside; Trimethaphan | 1985 |
Postural influences on the hemodynamic responses to vasodilating drugs in congestive heart failure.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Clonidine; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Posture; Pulmonary Artery; Pulmonary Wedge Pressure; Vascular Resistance; Vasodilator Agents | 1985 |
Further examination of the effects of ageing on the adrenoceptor responsiveness of the rat vas deferens.
Topics: Aging; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Nifedipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Vas Deferens; Xylazine | 1985 |
Importance of frequency and pulse with in field stimulation of the mouse vas deferens: different behaviour of twitch-inhibiting drugs.
Topics: Animals; Calcium; Clonidine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Electric Stimulation; Enkephalin, Methionine; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Nifedipine; Procaine; Tetrodotoxin; Vas Deferens; Verapamil | 1985 |
Effects of nifedipine on the hypotensive actions of alpha 2-agonists in conscious spontaneously hypertensive rats.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Drug Interactions; Guanabenz; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Nifedipine; Rats; Rats, Inbred SHR | 1984 |
Nifedipine and alpha adrenoceptors in rat aorta. I. Role of extracellular calcium in alpha-1 and alpha-2 adrenoceptor-mediated contraction.
Topics: Animals; Aorta; Calcium; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1984 |
Nifedipine and alpha adrenoceptors in rat aorta. II. Role of extracellular calcium in enhanced alpha-2 adrenoceptor-mediated contraction in diabetes.
Topics: Animals; Aorta; Calcium; Clonidine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
[The present status of treatment of hypertension (author's transl)].
Topics: Adrenergic beta-Antagonists; Captopril; Clonidine; Humans; Hypertension; Nifedipine; Prazosin | 1981 |
Differential effect of calcium entry blockers on alpha 1-adrenoceptor-mediated vasoconstriction in vivo.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Calcium Channel Blockers; Catecholamines; Clonidine; Ethanolamines; Imidazoles; Imidazolines; Male; Methoxamine; Nifedipine; Phenylephrine; Rats; Rats, Inbred Strains; Vasoconstriction; Verapamil | 1983 |
Use of nifedipine as an adjunct to current antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Vasodilator Agents | 1984 |
Sgd 101/75 is distinguished from other selective alpha 1-adrenoceptor agonists by the inhibition of its pressor responses by calcium entry blockade and vasodilatation in pithed rats and cats.
Topics: Adrenergic alpha-Agonists; Albuterol; Animals; Blood Pressure; Calcium Channel Blockers; Cats; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Male; Nifedipine; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation | 1983 |
The actions of cirazoline on the rat vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Imidazoles; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Prazosin; Rats; Rats, Inbred Strains; Synaptic Transmission; Vas Deferens | 1984 |
An oral calcium antagonist for treatment of hypertensive emergencies.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clonidine; Emergencies; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1982 |
The interaction of calcium antagonists (slow channel blockers) with myocardial alpha adrenoceptors.
Topics: Animals; Brain; Calcium Channel Blockers; Clonidine; Diltiazem; Gallopamil; In Vitro Techniques; Male; Myocardium; Nifedipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Verapamil | 1982 |
Antihypertensive drugs: their postural hypotensive effect and their blood pressure lowering activity in conscious normotensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hydrochlorothiazide; Hypotension, Orthostatic; Male; Minoxidil; Nicardipine; Nifedipine; Nitroprusside; Pentolinium Tartrate; Phentolamine; Prazosin; Rats; Rats, Inbred Strains | 1983 |
[The hypertensive crisis].
Topics: Acute Disease; Calcium Channel Blockers; Clonidine; Coronary Disease; Diazoxide; Dihydralazine; Diltiazem; Heart Failure; Humans; Hypertension; Nifedipine; Nitroprusside; Sympatholytics; Verapamil | 1984 |
Management of severe hypertension with nifedipine in combination with clonidine or propranolol.
Topics: Adult; Blood Pressure; Clonidine; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Propranolol; Pulse; Pyridines; Renin; Time Factors | 1980 |
The role of calcium and alpha-adrenoceptors in contractile response of chick expansor secundariorum muscle to field stimulation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Chloride; Chickens; Clonidine; Electric Stimulation; Ethanol; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscles; Nifedipine; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 1994 |
Inability of Ca2+ influx through nicotinic ACh receptor channels to stimulate catecholamine secretion in bovine adrenal chromaffin cells: studies with fura-2 and SBFI microfluorometry.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Calcium; Calcium Channels; Catecholamines; Cations, Divalent; Cattle; Clonidine; Cytophotometry; Dose-Response Relationship, Drug; Electrophysiology; Fura-2; Gallopamil; Guanethidine; Hexamethonium; Manganese; Nicotine; Nifedipine; Oxotremorine; Receptors, Nicotinic; Sodium; Spectrometry, Fluorescence | 1994 |
Increased sensitivity to inhibition by nifedipine of responses of the mesenteric artery bed of the SHRSP to noradrenaline is not dependent on alpha 1-adrenoceptor subtypes.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Hypertension; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Vascular Resistance | 1995 |
Characterization of alpha 1-adrenoceptor subtypes in tension response of human prostate to electrical field stimulation.
Topics: Adrenergic Antagonists; Animals; Clonidine; Electric Stimulation; Humans; Hyperplasia; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Nifedipine; Piperazines; Prazosin; Prostate; Rats; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens; Yohimbine | 1995 |
The difference in nifedipine sensitivity between hypertensive and normotensive rat aortae is dependent on age.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Aorta, Thoracic; Clonidine; Dioxanes; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred WKY | 1995 |
Effects of nifedipine on phasic and tonic vasoconstrictor responses to Sgd 101/75 in the isolated perfused rabbit ear artery.
Topics: Adrenergic alpha-Agonists; Animals; Arteries; Calcium; Clonidine; Ear; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Vasoconstriction | 1994 |
Alpha 1A-adrenoceptor subtype mediates contraction of the rat urethra.
Topics: Aminoquinolines; Animals; Calcium; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Tetrahydroisoquinolines; Urethra | 1994 |
Functional identification of alpha 1-adrenoceptor subtypes in human prostate: comparison with those in rat vas deferens and spleen.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens | 1994 |
[Therapy of arterial hypertension associated with acute stroke. Current trends and problems].
Topics: Acute Disease; Aged; Antihypertensive Agents; Blood Pressure Monitors; Cerebral Hemorrhage; Cerebrovascular Disorders; Clonidine; Emergencies; Humans; Hypertension; Intracranial Embolism and Thrombosis; Male; Nifedipine | 1994 |
Alpha 1-adrenoceptor subtype(s) mediating noradrenaline-induced contractions of the guinea-pig aorta.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clonidine; Dioxanes; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Oxazines; Prazosin; Receptors, Adrenergic, alpha-1 | 1994 |
Effect of nifedipine, a calcium channel inhibitor, on sedation produced by reserpine, clonidine and propranolol in mice.
Topics: Animals; Clonidine; Drug Interactions; Female; Hypnotics and Sedatives; Male; Mice; Nifedipine; Propranolol; Reserpine | 1994 |
Role of vascular alpha-1 adrenoceptor subtypes in the pressor response to sympathetic nerve stimulation in the pithed rat.
Topics: Animals; Blood Pressure; Blood Vessels; Clonidine; Decerebrate State; Dioxanes; Electric Stimulation; Idazoxan; Male; Nifedipine; Piperazines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System | 1994 |
Calcium channel blockers impair the pituitary-adrenocortical responses to central adrenergic receptors stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Clonidine; Corticosterone; Drug Interactions; Hypothalamo-Hypophyseal System; Isoproterenol; Male; Nifedipine; Phenylephrine; Pituitary-Adrenal System; Rats; Rats, Wistar; Stimulation, Chemical; Verapamil | 1993 |
[The clofelin and nifedipine treatment of hypertensive crises in elderly patients].
Topics: Aged; Chronic Disease; Clonidine; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Factors | 1993 |
ED management of acute congestive heart failure in renal dialysis patients.
Topics: Acute Disease; Administration, Cutaneous; Administration, Oral; Administration, Sublingual; Captopril; Clinical Protocols; Clonidine; Emergency Medical Services; Emergency Medicine; Heart Failure; Humans; Infusions, Intravenous; Intubation, Intratracheal; Kidney Failure, Chronic; Morphine; Nifedipine; Nitroglycerin; Nitroprusside; Oxygen Inhalation Therapy; Peritoneal Dialysis; Prospective Studies; Renal Dialysis; Severity of Illness Index; Transportation of Patients | 1993 |
Induction of cell expansion of goldfish melanocytoma cells (GMM-1) by epinephrine and dexamethasone requires external calcium.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cell Line; Cell Size; Clonidine; Colforsin; Dexamethasone; Diglycerides; Egtazic Acid; Epinephrine; Goldfish; Melanoma; Nifedipine; Receptors, Adrenergic; Tumor Cells, Cultured; Yohimbine | 1993 |
Stimulatory effect of norepinephrine on progesterone production by human first trimester placenta explants in vitro.
Topics: Atenolol; Clonidine; Culture Media, Serum-Free; Cyclic AMP; Female; Gadolinium; Gonadotropin-Releasing Hormone; Humans; Nifedipine; Norepinephrine; Organ Culture Techniques; Prazosin; Pregnancy; Pregnancy Trimester, First; Progesterone; Stimulation, Chemical; Trophoblasts; Yohimbine | 1993 |
Withdrawal contractures of guinea-pig isolated ileum after acute activation of kappa-opioid receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Nifedipine; Pyrrolidines; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 1993 |
Alpha 1A-adrenoceptor-mediated contractile responses of the human vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Binding, Competitive; Calcium; Clonidine; Extracellular Space; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Vas Deferens | 1995 |
Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Clonidine; Diabetes Mellitus, Experimental; Hypertension; Imidazoles; Nifedipine; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin | 1996 |
Actions of magnesium, nifedipine and clonidine on the fetal vasculature of the human placenta.
Topics: Antihypertensive Agents; Clonidine; Dose-Response Relationship, Drug; Female; Fetus; Humans; In Vitro Techniques; Magnesium; Nifedipine; Placenta; Vasodilation | 1996 |
Pharmacological characterization of alpha 1-adrenoceptors in porcine uterine artery.
Topics: Animals; Arteries; Calcium; Clonidine; Estrus; Female; In Vitro Techniques; Nifedipine; Norepinephrine; Phenylephrine; Pregnancy; Pregnancy, Animal; Receptors, Adrenergic, alpha-1; Swine; Uterus | 1996 |
Antihypertensive effects of a new transdermal delivery system for clonidine in genetic and experimental hypertensive rats.
Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Desoxycorticosterone; Galvanic Skin Response; Hypertension; Hypertension, Renovascular; Male; Nifedipine; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Trichlormethiazide | 1996 |
Hypotensive effects of a new transdermal delivery system for clonidine (M-5041T) in spontaneously and renal hypertensive rats.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Desoxycorticosterone; Heart Rate; Hypertension; Hypertension, Renovascular; Male; Nifedipine; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Sodium Chloride; Trichlormethiazide | 1995 |
Heterogeneity and complexity of alpha 1-adrenoceptors in the ovine uterine artery and umbilical vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Binding, Competitive; Calcium Channel Blockers; Clonidine; Dioxanes; Drug Interactions; Drug Synergism; Female; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Prazosin; Pregnancy; Receptors, Adrenergic, alpha-1; Sheep; Umbilical Veins; Uterus; Vasoconstriction | 1997 |
Alpha 1-adrenoceptor subtype involved in the positive and negative inotropic responses to phenylephrine in rat papillary muscle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Carcinogens; Cardiotonic Agents; Clonidine; Dioxanes; Electrophysiology; In Vitro Techniques; Myocardial Contraction; Nifedipine; Papillary Muscles; Phenylephrine; Phorbol 12,13-Dibutyrate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1997 |
The use of glucagon in nifedipine poisoning complicated by clonidine ingestion.
Topics: Adolescent; Antidotes; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Drug Interactions; Drug Overdose; Female; Glucagon; Humans; Nifedipine; Poisoning | 1997 |
[Premedication with different groups of hypotensive drugs in preparation of patients with concomitant arterial hypertension to planned surgical treatment].
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Female; Humans; Hypertension; Hysterectomy; Leiomyoma; Middle Aged; Nifedipine; Premedication; Propranolol; Time Factors; Uterine Neoplasms | 1998 |
Clonidine and vasomotion physiology.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Calcium; Cattle; Clonidine; Drug Synergism; In Vitro Techniques; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Yohimbine | 1998 |
Discrimination of alpha1-adrenoceptor subtypes in rat aorta and prostate.
Topics: Acetonitriles; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Piperazines; Prazosin; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Vasoconstriction; Vasodilator Agents | 1998 |
Effects of the selective cyclooxygenase-2 inhibitor nimesulide on vascular contractions in endothelium-denuded rat aorta.
Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Clonidine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelin-1; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Muscle Contraction; Nifedipine; Phenylephrine; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides | 1998 |
Transient left ventricular failure following bilateral lung transplantation for pulmonary hypertension.
Topics: Adult; Alprostadil; Antihypertensive Agents; Cardiac Output, Low; Cardiotonic Agents; Catheterization, Swan-Ganz; Clonidine; Dobutamine; Echocardiography; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Transplantation; Male; Nifedipine; Respiratory Insufficiency; Treatment Outcome; Vasodilator Agents; Ventricular Dysfunction, Left | 1999 |
Clinical presentation and management of patients with uncontrolled, severe hypertension: results from a public teaching hospital.
Topics: Acute Disease; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Cross-Sectional Studies; Emergency Service, Hospital; Female; Florida; Follow-Up Studies; Hospitals, Public; Hospitals, Teaching; Humans; Hypertension; Incidence; Male; Middle Aged; Nifedipine; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 1999 |
Expression and pharmacological characterization of alpha1-adrenoceptors in rat seminal vesicle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Epinephrine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenoxybenzamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seminal Vesicles | 1999 |
Differential blockade of alpha,beta-methylene-ATP, noradrenaline and electrically evoked contractions of the rat vas deferens.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Clonidine; Cromakalim; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Nifedipine; Norepinephrine; Papaverine; Rats; Rats, Wistar; Vas Deferens; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 1999 |
[New central agents in the treatment of arterial hypertension].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Clonidine; Diabetes Complications; Humans; Hypertension; Imidazoles; Nifedipine; Oxazoles; Renin-Angiotensin System; Reserpine; Rilmenidine; Risk Factors; Sympathetic Nervous System; Vasodilator Agents | 1999 |
The differential effects of calcium channel blockers in the behavioural despair test in mice.
Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Clomipramine; Clonidine; Cyproheptadine; Depression; Desipramine; Diltiazem; Drug Interactions; Female; Male; Mianserin; Mice; Motor Activity; Nifedipine; Tranylcypromine; Verapamil | 2000 |
[When hypertension becomes an emergency case: lower the blood pressure, but slowly!].
Topics: Administration, Oral; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Diagnosis, Differential; Dihydralazine; Emergencies; Hospitalization; Humans; Hypertension; Hypertension, Malignant; Injections, Intravenous; Nifedipine; Nitrendipine; Nitroglycerin; Piperazines; Time Factors; Vasodilator Agents | 2003 |
Sympathetic neurotransmission in the rat testicular capsule: functional characterization and identification of mRNA encoding alpha1-adrenoceptor subtypes.
Topics: Acetyl-CoA C-Acyltransferase; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Male; Muscle Contraction; Nifedipine; Norepinephrine; Prazosin; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P2; Reserpine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spiperone; Suramin; Sympathetic Nervous System; Synaptic Transmission; Testis | 2006 |
[Emergency checklist in hypertensive crisis].
Topics: Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Clonidine; Diuretics; Emergencies; Female; Furosemide; Hospitalization; Humans; Hypertension; Male; Medical History Taking; Nifedipine; Nitrendipine; Pregnancy; Vasodilator Agents | 2006 |
Effects of nine antihypertensive drugs on blood pressure variability in sinoaortic-denervated rats.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Calcium Channel Blockers; Carotid Sinus; Clonidine; Denervation; Heart Rate; Hypertension; Male; Nifedipine; Pressoreceptors; Random Allocation; Rats; Rats, Sprague-Dawley; Sympatholytics | 2006 |
PRES: posterior or potentially reversible encephalopathy syndrome?
Topics: Adult; Anti-Inflammatory Agents; Anticonvulsants; Antihypertensive Agents; Brain; Brain Diseases; Clonidine; Dexamethasone; Diazepam; Diuretics, Osmotic; Eclampsia; Female; Humans; Magnesium Sulfate; Magnetic Resonance Imaging; Mannitol; Nifedipine; Pregnancy; Seizures | 2006 |
Epinephrine, phenylephrine, and methoxamine induce infiltrative anesthesia via alpha1-adrenoceptors in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Anesthesia, Local; Anesthetics, Local; Animals; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Male; Methoxamine; Nifedipine; Nitroglycerin; Pain Measurement; Phentolamine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 2009 |
[Acute management at the rising of arterial pressure which is not menacing to a life].
Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Clonidine; Electrocardiography; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Nifedipine; Severity of Illness Index; Sympatholytics; Treatment Outcome | 2011 |
Prominent contribution of L-type Ca2+ channels to cutaneous neurovascular transmission that is revealed after spinal cord injury augments vasoconstriction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Clonidine; Electric Stimulation; Endothelium, Vascular; Male; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Skin; Spinal Cord; Spinal Cord Injuries; Stimulation, Chemical; Sympathetic Nervous System; Sympatholytics; Vasoconstriction; Vasodilation | 2012 |
[Clinical survey of tizanidine-induced adverse effects--impact of concomitant drugs providing cytochrome P450 1A2 modification--].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Blood Pressure; Carbamazepine; Clonidine; Cytochrome P-450 CYP1A2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; Heart Rate; Humans; Male; Middle Aged; Nifedipine; Retrospective Studies; Time Factors | 2013 |