nifedipine has been researched along with cimetidine in 57 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 14 (24.56) | 18.7374 |
1990's | 12 (21.05) | 18.2507 |
2000's | 14 (24.56) | 29.6817 |
2010's | 16 (28.07) | 24.3611 |
2020's | 1 (1.75) | 2.80 |
Authors | Studies |
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Herbette, LG; Mason, RP; Rhodes, DG | 1 |
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Pratim Roy, P; Roy, K | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Dixon, JS; Khan, A; Langley, SJ; Mullins, FG; Toon, S | 1 |
al-Mashhadani, WM; al-Taie, RI; al-Zahawi, HM; Karim, KH | 1 |
Bäärnhielm, C; Berntsson, P; Brian, WR; Guengerich, FP; Iwasaki, M; Sari, MA | 1 |
Banerjee, RK; Bhattacharjee, M; Bose, AK | 1 |
Abernethy, DR | 1 |
Breimer, DD; Brugman, M; Schellens, JH; van der Wart, JH | 1 |
Breimer, DD; Danhof, M; Lodewijks, MT; van Brummelen, P; van Harten, J | 1 |
Benet, LZ; Lin, ET; Schwartz, JB; Upton, RA; Williams, RL | 1 |
Beerahee, A; Jack, DB; Kendall, MJ; Lobo, J; Smith, SR; Wilkins, MR | 1 |
Challenor, VF; George, CF; Gruchy, B; Le Vie, J; Renwick, AG; Waller, DG | 1 |
Kotlikoff, MI; Murray, RK; Reynolds, EE | 1 |
Bommer, M; Herz, A; Kley, N; Liebisch, D; Noble, E | 1 |
Heidemann, H; Hutt, HJ; Janisch, HD; Kirch, W; Ohnhaus, EE; Rämsch, K | 1 |
Janisch, HD; Kirch, W; Ohnhaus, EE; Rämsch, K | 1 |
Heidemann, H; Janisch, HD; Kirch, W; Ohnhaus, EE; Rämsch, K | 1 |
Baskin, EP; Winquist, RJ | 1 |
Buters, JT; Friedman, FK; Koley, AP; Markowitz, A; Robinson, RC | 1 |
Ring, BJ; Wrighton, SA | 1 |
Baux, G; Fossier, P; Tauc, L; Trudeau, LE | 1 |
Bevan, JA; Henrion, D; Klaasen, A; Laher, I | 1 |
Bauer, JW; Egger, C; Fischer-Colbrie, R; Kirchmair, R | 1 |
Abdel-Maged, AI; el Hawy, AM; el-Rakaybe, A; Mansour, RE; Negm, IA | 1 |
Haragsim, L; Nĕmecek, K; Zima, T | 1 |
Brown, CD; Dudley, AJ | 1 |
Bevan, JA; Gokina, NI | 1 |
Badawy, MM; Gaafa, KM; Hamza, AA | 1 |
Aarons, L; Darwich, A; Dressman, J; Hansmann, S; Margolskee, A | 1 |
Bezabhe, WM; Bezabih, YM; Bimrew, MA | 1 |
3 review(s) available for nifedipine and cimetidine
Article | Year |
---|---|
Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes.
Topics: Cell Membrane; Chemical Phenomena; Chemistry, Physical; Kinetics; Lipid Bilayers; Membrane Lipids; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship | 1991 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The pharmacokinetic profile of amlodipine.
Topics: Administration, Oral; Aging; Amlodipine; Angina Pectoris; Animals; Biological Availability; Calcium Channel Blockers; Cimetidine; Digoxin; Drug Interactions; Half-Life; Humans; Injections, Intravenous; Kidney Diseases; Liver Cirrhosis; Nifedipine | 1989 |
3 trial(s) available for nifedipine and cimetidine
Article | Year |
---|---|
The pharmacokinetics and pharmacodynamics of nifedipine at steady state during concomitant administration of cimetidine or high dose ranitidine.
Topics: Adult; Blood Pressure; Cimetidine; Drug Interactions; Humans; Male; Nifedipine; Ranitidine | 1991 |
Ranitidine and cimetidine; drug interactions with single dose and steady-state nifedipine administration.
Topics: Adolescent; Adult; Biological Availability; Cimetidine; Drug Interactions; Humans; Kinetics; Nifedipine; Ranitidine | 1987 |
[Effect of cimetidine and ranitidine on the pharmacokinetics and anti-hypertensive effect of nifedipine].
Topics: Adult; Blood Pressure; Cimetidine; Clinical Trials as Topic; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Heart Rate; Humans; Hypertension; Kinetics; Nifedipine; Ranitidine | 1983 |
51 other study(ies) available for nifedipine and cimetidine
Article | Year |
---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Nifedipine versus cimetidine in prevention of stress-induced gastric ulcers in rats.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Cold Temperature; Gastric Mucosa; Mast Cells; Nifedipine; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach Ulcer; Stress, Psychological | 1991 |
Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P-450 IIIA4.
Topics: Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cimetidine; Cytochrome P-450 Enzyme System; Dihydropyridines; Felodipine; Humans; Kinetics; Microsomes, Liver; Nifedipine; Norpregnenes; Oxidation-Reduction | 1991 |
Histamine H2-receptor mediated stimulation of gastric acid secretion by mercaptomethylimidazole.
Topics: Animals; Cimetidine; Gastric Acid; Male; Methimazole; Mice; Mice, Inbred BALB C; Nifedipine; Omeprazole; Parietal Cells, Gastric; Potassium; Proton-Translocating ATPases; Pylorus; Receptors, Histamine H2; Sodium; Verapamil | 1989 |
Influence of enzyme induction and inhibition on the oxidation of nifedipine, sparteine, mephenytoin and antipyrine in humans as assessed by a "cocktail" study design.
Topics: Adult; Antipyrine; Cimetidine; Enzyme Induction; Female; Humans; Hydantoins; Male; Mephenytoin; Metabolic Clearance Rate; Nifedipine; Oxidation-Reduction; Phenobarbital; Smoking; Sparteine | 1989 |
Pharmacokinetics and hemodynamic effects of nisoldipine and its interaction with cimetidine.
Topics: Administration, Oral; Adult; Blood Pressure; Calcium Channel Blockers; Cimetidine; Half-Life; Heart Rate; Humans; Injections, Intravenous; Nifedipine; Nisoldipine | 1988 |
Effect of cimetidine or ranitidine administration on nifedipine pharmacokinetics and pharmacodynamics.
Topics: Adult; Blood Pressure; Cimetidine; Drug Interactions; Female; Heart Rate; Humans; Male; Nifedipine; Ranitidine | 1988 |
Factors affecting the pharmacokinetics of nifedipine.
Topics: Adult; Cimetidine; Cytochrome P-450 Enzyme System; Drug Interactions; Half-Life; Humans; Kinetics; Male; Nifedipine; Ranitidine; Smoking | 1987 |
Histamine-induced calcium release and phorbol antagonism in cultured airway smooth muscle cells.
Topics: Animals; Benzofurans; Calcium; Cells, Cultured; Cimetidine; Dogs; Dose-Response Relationship, Drug; Fura-2; Histamine; Mathematics; Muscle, Smooth; Nifedipine; Pyrilamine; Receptors, Histamine H1; Tetradecanoylphorbol Acetate; Trachea | 1987 |
Histamine affects release and biosynthesis of opioid peptides primarily via H1-receptors in bovine chromaffin cells.
Topics: Adrenal Glands; Animals; Calcium; Cattle; Cells, Cultured; Chromaffin System; Cimetidine; Clemastine; Cobalt; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Gallopamil; Histamine; Histamine Antagonists; Nifedipine; Protein Precursors; Pyrilamine; Ranitidine; Receptors, Histamine; Receptors, Histamine H1; RNA, Messenger | 1987 |
Drug interactions with nitrendipine.
Topics: Adrenergic beta-Antagonists; Adult; Calcium Channel Blockers; Chromatography, Gas; Cimetidine; Digitalis Glycosides; Digoxin; Drug Interactions; Female; Histamine H2 Antagonists; Humans; Kinetics; Male; Nifedipine; Nitrendipine; Ranitidine | 1984 |
The influence of two histamine H2-receptor antagonists, cimetidine and ranitidine, on the plasma levels and clinical effect of nifedipine and metoprolol.
Topics: Adult; Cimetidine; Drug Interactions; Histamine H2 Antagonists; Humans; Male; Metoprolol; Nifedipine; Ranitidine | 1984 |
Calcium channels resistant to organic calcium entry blockers in a rabbit vein.
Topics: Animals; Benzazepines; Calcium; Cimetidine; Diltiazem; Dose-Response Relationship, Drug; Face; Histamine; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phentolamine; Propranolol; Rabbits; Temperature; Veins; Verapamil | 1983 |
CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.
Topics: Animals; Carbon Monoxide; Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Ethinyl Estradiol; Humans; Kinetics; Mixed Function Oxygenases; Nifedipine; Protein Binding; Quinidine; Recombinant Proteins; Spodoptera; Substrate Specificity; Testosterone; Time Factors; Transfection; Warfarin | 1995 |
Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine.
Topics: Chromatography, High Pressure Liquid; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Humans; In Vitro Techniques; Ketoconazole; Microsomes, Liver; Midazolam; Nifedipine; Nizatidine | 1994 |
Transmitter release and calcium currents at an Aplysia buccal ganglion synapse--II. Modulation by presynaptic receptors.
Topics: Animals; Aplysia; Calcium Channels; Cimetidine; Ganglia; GTP-Binding Proteins; Guanosine Diphosphate; Histamine; In Vitro Techniques; Neuropeptides; Neurotransmitter Agents; Nifedipine; Oligopeptides; Parasympathetic Nervous System; Synapses; Synaptic Transmission; Thionucleotides | 1993 |
Myogenic tone of rabbit facial vein and posterior cerebral artery is influenced by changes in extracellular sodium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Analysis of Variance; Animals; Bicarbonates; Cerebral Arteries; Cimetidine; Histamine; In Vitro Techniques; Isometric Contraction; Meglumine; Monensin; Mouth; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Ouabain; Propranolol; Rabbits; Sodium; Veins | 1994 |
Histamine induces a gene-specific synthesis regulation of secretogranin II but not of chromogranin A and B in chromaffin cells in a calcium-dependent manner.
Topics: Adrenal Medulla; Animals; Blotting, Northern; Calcium; Cattle; Cells, Cultured; Chromaffin System; Chromogranin A; Chromogranins; Cimetidine; Gene Expression Regulation; Histamine; Kinetics; Nifedipine; Promethazine; Proteins; RNA, Messenger | 1993 |
The effect of nifedipine [correction of nifidipine] and cimetidine on the haemodynamics of Egyptian bilharzial pulmonary hypertension.
Topics: Blood Pressure; Cimetidine; Humans; Hypertension, Pulmonary; Nifedipine; Random Allocation; Schistosomiasis | 1993 |
Nephrotoxic effects of platinum cytostatics--preventative effects of nifedipine and cimetidine.
Topics: Animals; Antineoplastic Agents; Calcium Channel Blockers; Carboplatin; Cimetidine; Cisplatin; Kidney; Male; Nifedipine; Rats; Rats, Wistar | 1994 |
Mediation of cimetidine secretion by P-glycoprotein and a novel H(+)-coupled mechanism in cultured renal epithelial monolayers of LLC-PK1 cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Membrane Permeability; Cimetidine; Epithelium; Hydrogen-Ion Concentration; Kidney; LLC-PK1 Cells; Nifedipine; Swine; Verapamil | 1996 |
Histamine-induced depolarization: ionic mechanisms and role in sustained contraction of rabbit cerebral arteries.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cerebral Arteries; Cimetidine; Cobalt; Electrophysiology; Endothelium, Vascular; Extracellular Space; Histamine; Histamine H2 Antagonists; Ions; Male; Membrane Potentials; Nifedipine; Potassium; Rabbits; Sodium; Solutions; Vasoconstriction | 2000 |
The protective effects of ascorbic acid, cimetidine, and nifedipine on diethyldithiocarbamate-induced hepatic toxicity in albino rats.
Topics: Animals; Ascorbic Acid; Biomarkers; Calcium; Chemical and Drug Induced Liver Injury; Cimetidine; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Glutathione; Lipid Peroxidation; Liver; Male; Malondialdehyde; Nifedipine; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Time Factors | 2011 |
Forecasting oral absorption across biopharmaceutics classification system classes with physiologically based pharmacokinetic models.
Topics: Administration, Intravenous; Administration, Oral; Animals; Biological Availability; Biopharmaceutics; Biotransformation; Bisoprolol; Cimetidine; Computer Simulation; Drug Compounding; Forecasting; Furosemide; Gastrointestinal Absorption; Humans; Models, Biological; Nifedipine; Permeability; Reproducibility of Results | 2016 |
Hypocalcemic tetany associated with simultaneous administration of cimetidine and nifedipine: a case report.
Topics: Calcium Gluconate; Cimetidine; Dyspepsia; Female; Humans; Hypocalcemia; Middle Aged; Nifedipine; Spasm; Tetany | 2023 |