nifedipine and cimetidine

nifedipine has been researched along with cimetidine in 57 studies

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-199014 (24.56)18.7374
1990's12 (21.05)18.2507
2000's14 (24.56)29.6817
2010's16 (28.07)24.3611
2020's1 (1.75)2.80

Authors

AuthorsStudies
Herbette, LG; Mason, RP; Rhodes, DG1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Pratim Roy, P; Roy, K1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dixon, JS; Khan, A; Langley, SJ; Mullins, FG; Toon, S1
al-Mashhadani, WM; al-Taie, RI; al-Zahawi, HM; Karim, KH1
Bäärnhielm, C; Berntsson, P; Brian, WR; Guengerich, FP; Iwasaki, M; Sari, MA1
Banerjee, RK; Bhattacharjee, M; Bose, AK1
Abernethy, DR1
Breimer, DD; Brugman, M; Schellens, JH; van der Wart, JH1
Breimer, DD; Danhof, M; Lodewijks, MT; van Brummelen, P; van Harten, J1
Benet, LZ; Lin, ET; Schwartz, JB; Upton, RA; Williams, RL1
Beerahee, A; Jack, DB; Kendall, MJ; Lobo, J; Smith, SR; Wilkins, MR1
Challenor, VF; George, CF; Gruchy, B; Le Vie, J; Renwick, AG; Waller, DG1
Kotlikoff, MI; Murray, RK; Reynolds, EE1
Bommer, M; Herz, A; Kley, N; Liebisch, D; Noble, E1
Heidemann, H; Hutt, HJ; Janisch, HD; Kirch, W; Ohnhaus, EE; Rämsch, K1
Janisch, HD; Kirch, W; Ohnhaus, EE; Rämsch, K1
Heidemann, H; Janisch, HD; Kirch, W; Ohnhaus, EE; Rämsch, K1
Baskin, EP; Winquist, RJ1
Buters, JT; Friedman, FK; Koley, AP; Markowitz, A; Robinson, RC1
Ring, BJ; Wrighton, SA1
Baux, G; Fossier, P; Tauc, L; Trudeau, LE1
Bevan, JA; Henrion, D; Klaasen, A; Laher, I1
Bauer, JW; Egger, C; Fischer-Colbrie, R; Kirchmair, R1
Abdel-Maged, AI; el Hawy, AM; el-Rakaybe, A; Mansour, RE; Negm, IA1
Haragsim, L; Nĕmecek, K; Zima, T1
Brown, CD; Dudley, AJ1
Bevan, JA; Gokina, NI1
Badawy, MM; Gaafa, KM; Hamza, AA1
Aarons, L; Darwich, A; Dressman, J; Hansmann, S; Margolskee, A1
Bezabhe, WM; Bezabih, YM; Bimrew, MA1

Reviews

3 review(s) available for nifedipine and cimetidine

ArticleYear
Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Cell Membrane; Chemical Phenomena; Chemistry, Physical; Kinetics; Lipid Bilayers; Membrane Lipids; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship

1991
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The pharmacokinetic profile of amlodipine.
    American heart journal, 1989, Volume: 118, Issue:5 Pt 2

    Topics: Administration, Oral; Aging; Amlodipine; Angina Pectoris; Animals; Biological Availability; Calcium Channel Blockers; Cimetidine; Digoxin; Drug Interactions; Half-Life; Humans; Injections, Intravenous; Kidney Diseases; Liver Cirrhosis; Nifedipine

1989

Trials

3 trial(s) available for nifedipine and cimetidine

ArticleYear
The pharmacokinetics and pharmacodynamics of nifedipine at steady state during concomitant administration of cimetidine or high dose ranitidine.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:4

    Topics: Adult; Blood Pressure; Cimetidine; Drug Interactions; Humans; Male; Nifedipine; Ranitidine

1991
Ranitidine and cimetidine; drug interactions with single dose and steady-state nifedipine administration.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Biological Availability; Cimetidine; Drug Interactions; Humans; Kinetics; Nifedipine; Ranitidine

1987
[Effect of cimetidine and ranitidine on the pharmacokinetics and anti-hypertensive effect of nifedipine].
    Deutsche medizinische Wochenschrift (1946), 1983, Nov-18, Volume: 108, Issue:46

    Topics: Adult; Blood Pressure; Cimetidine; Clinical Trials as Topic; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Heart Rate; Humans; Hypertension; Kinetics; Nifedipine; Ranitidine

1983

Other Studies

51 other study(ies) available for nifedipine and cimetidine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:7

    Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Nifedipine versus cimetidine in prevention of stress-induced gastric ulcers in rats.
    European journal of pharmacology, 1991, Jan-03, Volume: 192, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Cold Temperature; Gastric Mucosa; Mast Cells; Nifedipine; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach Ulcer; Stress, Psychological

1991
Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P-450 IIIA4.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:6

    Topics: Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cimetidine; Cytochrome P-450 Enzyme System; Dihydropyridines; Felodipine; Humans; Kinetics; Microsomes, Liver; Nifedipine; Norpregnenes; Oxidation-Reduction

1991
Histamine H2-receptor mediated stimulation of gastric acid secretion by mercaptomethylimidazole.
    Biochemical pharmacology, 1989, Mar-15, Volume: 38, Issue:6

    Topics: Animals; Cimetidine; Gastric Acid; Male; Methimazole; Mice; Mice, Inbred BALB C; Nifedipine; Omeprazole; Parietal Cells, Gastric; Potassium; Proton-Translocating ATPases; Pylorus; Receptors, Histamine H2; Sodium; Verapamil

1989
Influence of enzyme induction and inhibition on the oxidation of nifedipine, sparteine, mephenytoin and antipyrine in humans as assessed by a "cocktail" study design.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2

    Topics: Adult; Antipyrine; Cimetidine; Enzyme Induction; Female; Humans; Hydantoins; Male; Mephenytoin; Metabolic Clearance Rate; Nifedipine; Oxidation-Reduction; Phenobarbital; Smoking; Sparteine

1989
Pharmacokinetics and hemodynamic effects of nisoldipine and its interaction with cimetidine.
    Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:3

    Topics: Administration, Oral; Adult; Blood Pressure; Calcium Channel Blockers; Cimetidine; Half-Life; Heart Rate; Humans; Injections, Intravenous; Nifedipine; Nisoldipine

1988
Effect of cimetidine or ranitidine administration on nifedipine pharmacokinetics and pharmacodynamics.
    Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:6

    Topics: Adult; Blood Pressure; Cimetidine; Drug Interactions; Female; Heart Rate; Humans; Male; Nifedipine; Ranitidine

1988
Factors affecting the pharmacokinetics of nifedipine.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:4

    Topics: Adult; Cimetidine; Cytochrome P-450 Enzyme System; Drug Interactions; Half-Life; Humans; Kinetics; Male; Nifedipine; Ranitidine; Smoking

1987
Histamine-induced calcium release and phorbol antagonism in cultured airway smooth muscle cells.
    The American journal of physiology, 1987, Volume: 253, Issue:4 Pt 1

    Topics: Animals; Benzofurans; Calcium; Cells, Cultured; Cimetidine; Dogs; Dose-Response Relationship, Drug; Fura-2; Histamine; Mathematics; Muscle, Smooth; Nifedipine; Pyrilamine; Receptors, Histamine H1; Tetradecanoylphorbol Acetate; Trachea

1987
Histamine affects release and biosynthesis of opioid peptides primarily via H1-receptors in bovine chromaffin cells.
    Journal of neurochemistry, 1987, Volume: 49, Issue:6

    Topics: Adrenal Glands; Animals; Calcium; Cattle; Cells, Cultured; Chromaffin System; Cimetidine; Clemastine; Cobalt; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Gallopamil; Histamine; Histamine Antagonists; Nifedipine; Protein Precursors; Pyrilamine; Ranitidine; Receptors, Histamine; Receptors, Histamine H1; RNA, Messenger

1987
Drug interactions with nitrendipine.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 7

    Topics: Adrenergic beta-Antagonists; Adult; Calcium Channel Blockers; Chromatography, Gas; Cimetidine; Digitalis Glycosides; Digoxin; Drug Interactions; Female; Histamine H2 Antagonists; Humans; Kinetics; Male; Nifedipine; Nitrendipine; Ranitidine

1984
The influence of two histamine H2-receptor antagonists, cimetidine and ranitidine, on the plasma levels and clinical effect of nifedipine and metoprolol.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1984, Volume: 7

    Topics: Adult; Cimetidine; Drug Interactions; Histamine H2 Antagonists; Humans; Male; Metoprolol; Nifedipine; Ranitidine

1984
Calcium channels resistant to organic calcium entry blockers in a rabbit vein.
    The American journal of physiology, 1983, Volume: 245, Issue:6

    Topics: Animals; Benzazepines; Calcium; Cimetidine; Diltiazem; Dose-Response Relationship, Drug; Face; Histamine; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phentolamine; Propranolol; Rabbits; Temperature; Veins; Verapamil

1983
CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.
    The Journal of biological chemistry, 1995, Mar-10, Volume: 270, Issue:10

    Topics: Animals; Carbon Monoxide; Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Ethinyl Estradiol; Humans; Kinetics; Mixed Function Oxygenases; Nifedipine; Protein Binding; Quinidine; Recombinant Proteins; Spodoptera; Substrate Specificity; Testosterone; Time Factors; Transfection; Warfarin

1995
Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine.
    Pharmaceutical research, 1994, Volume: 11, Issue:6

    Topics: Chromatography, High Pressure Liquid; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Humans; In Vitro Techniques; Ketoconazole; Microsomes, Liver; Midazolam; Nifedipine; Nizatidine

1994
Transmitter release and calcium currents at an Aplysia buccal ganglion synapse--II. Modulation by presynaptic receptors.
    Neuroscience, 1993, Volume: 53, Issue:2

    Topics: Animals; Aplysia; Calcium Channels; Cimetidine; Ganglia; GTP-Binding Proteins; Guanosine Diphosphate; Histamine; In Vitro Techniques; Neuropeptides; Neurotransmitter Agents; Nifedipine; Oligopeptides; Parasympathetic Nervous System; Synapses; Synaptic Transmission; Thionucleotides

1993
Myogenic tone of rabbit facial vein and posterior cerebral artery is influenced by changes in extracellular sodium.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Analysis of Variance; Animals; Bicarbonates; Cerebral Arteries; Cimetidine; Histamine; In Vitro Techniques; Isometric Contraction; Meglumine; Monensin; Mouth; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Ouabain; Propranolol; Rabbits; Sodium; Veins

1994
Histamine induces a gene-specific synthesis regulation of secretogranin II but not of chromogranin A and B in chromaffin cells in a calcium-dependent manner.
    The Journal of biological chemistry, 1993, Jan-25, Volume: 268, Issue:3

    Topics: Adrenal Medulla; Animals; Blotting, Northern; Calcium; Cattle; Cells, Cultured; Chromaffin System; Chromogranin A; Chromogranins; Cimetidine; Gene Expression Regulation; Histamine; Kinetics; Nifedipine; Promethazine; Proteins; RNA, Messenger

1993
The effect of nifedipine [correction of nifidipine] and cimetidine on the haemodynamics of Egyptian bilharzial pulmonary hypertension.
    Journal of the Egyptian Society of Parasitology, 1993, Volume: 23, Issue:1

    Topics: Blood Pressure; Cimetidine; Humans; Hypertension, Pulmonary; Nifedipine; Random Allocation; Schistosomiasis

1993
Nephrotoxic effects of platinum cytostatics--preventative effects of nifedipine and cimetidine.
    Sbornik lekarsky, 1994, Volume: 95, Issue:3

    Topics: Animals; Antineoplastic Agents; Calcium Channel Blockers; Carboplatin; Cimetidine; Cisplatin; Kidney; Male; Nifedipine; Rats; Rats, Wistar

1994
Mediation of cimetidine secretion by P-glycoprotein and a novel H(+)-coupled mechanism in cultured renal epithelial monolayers of LLC-PK1 cells.
    British journal of pharmacology, 1996, Volume: 117, Issue:6

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Membrane Permeability; Cimetidine; Epithelium; Hydrogen-Ion Concentration; Kidney; LLC-PK1 Cells; Nifedipine; Swine; Verapamil

1996
Histamine-induced depolarization: ionic mechanisms and role in sustained contraction of rabbit cerebral arteries.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:6

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cerebral Arteries; Cimetidine; Cobalt; Electrophysiology; Endothelium, Vascular; Extracellular Space; Histamine; Histamine H2 Antagonists; Ions; Male; Membrane Potentials; Nifedipine; Potassium; Rabbits; Sodium; Solutions; Vasoconstriction

2000
The protective effects of ascorbic acid, cimetidine, and nifedipine on diethyldithiocarbamate-induced hepatic toxicity in albino rats.
    Drug and chemical toxicology, 2011, Volume: 34, Issue:4

    Topics: Animals; Ascorbic Acid; Biomarkers; Calcium; Chemical and Drug Induced Liver Injury; Cimetidine; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Glutathione; Lipid Peroxidation; Liver; Male; Malondialdehyde; Nifedipine; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Time Factors

2011
Forecasting oral absorption across biopharmaceutics classification system classes with physiologically based pharmacokinetic models.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:12

    Topics: Administration, Intravenous; Administration, Oral; Animals; Biological Availability; Biopharmaceutics; Biotransformation; Bisoprolol; Cimetidine; Computer Simulation; Drug Compounding; Forecasting; Furosemide; Gastrointestinal Absorption; Humans; Models, Biological; Nifedipine; Permeability; Reproducibility of Results

2016
Hypocalcemic tetany associated with simultaneous administration of cimetidine and nifedipine: a case report.
    Journal of medical case reports, 2023, Jul-28, Volume: 17, Issue:1

    Topics: Calcium Gluconate; Cimetidine; Dyspepsia; Female; Humans; Hypocalcemia; Middle Aged; Nifedipine; Spasm; Tetany

2023