nifedipine has been researched along with carbamazepine in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.35) | 18.7374 |
| 1990's | 5 (10.87) | 18.2507 |
| 2000's | 16 (34.78) | 29.6817 |
| 2010's | 23 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Burk, O; Eichelbaum, M; Geick, A | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Antkiewicz-Michaluk, L; Marona, H; Pekala, E; Szneler, E; Walczak, M | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Sen, S; Sinha, N | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bahls, FH; Ozuna, J; Ritchie, DE | 1 |
| Carpenter, CL; Cooper, EC; Greenberg, DA | 1 |
| Calabresi, P; De Murtas, M; Marciani, MG; Mercuri, NB; Pisani, A; Stefani, A | 1 |
| Ikeda, M; Kamata, R; Kasamo, K; Kojima, T; Nogami, Y; Okuhata, Y; Satoh, R; Takahashi, S | 1 |
| Pleuvry, BJ; Rodger, C | 1 |
| Barra, Y; Bourgarel-Rey, V; Charvet, B; Desobry, A; Mesdjian, E; Mirrione, A; Sérée, E | 1 |
| Tateishi, T; Yasui-Furukori, N | 1 |
| Dasbach, TP; Mitchell, SA; Reynolds, TD | 1 |
| Bodmeier, R; Friedrich, H; Fussnegger, B; Kolter, K | 1 |
| de Morais, SM; Fahmi, OA; Liras, JL; Maurer, TS; Mills, JB; Ripp, SL; Trevena, KA | 1 |
| Kitano, H; Shinohara, H; Zakir Hossain, SM | 1 |
| Benotti, MJ; Brownawell, BJ | 1 |
| Bley, H; Bodmeier, R; Fussnegger, B | 1 |
| Hayashi, M; Shou, M; Skiles, GL; Xu, Y; Zhou, Y | 1 |
| Dürig, T; Hussain, M; Reed, C; Talukder, R | 1 |
| Homma, M; Kohda, Y; Matsumoto, S; Momo, K; Sasaki, T | 1 |
| Gu, L; Hertz, L; Li, B; Peng, L; Yan, E | 1 |
| Aoki, H; Itai, S; Iwao, Y; Mizoguchi, M; Noguchi, S; Watanabe, M | 1 |
| Adongo, DW; Mante, PK; Woode, E | 1 |
1 review(s) available for nifedipine and carbamazepine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
45 other study(ies) available for nifedipine and carbamazepine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogPoct: a tool for lipophilicity determination in drug discovery.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents | 2000 |
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Dimerization; DNA; DNA Primers; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestines; Molecular Sequence Data; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Rifampin; Transcription Factors | 2001 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Anticonvulsant activity of some xanthone derivatives.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Mice; Molecular Structure; Pentylenetetrazole; Rats; Seizures; Xanthones | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Interactions between calcium channel blockers and the anticonvulsants carbamazepine and phenytoin.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Carbamazepine; Diltiazem; Drug Interactions; Female; Humans; Male; Middle Aged; Nifedipine; Phenytoin; Retrospective Studies; Seizures; Verapamil | 1991 |
Phenytoin interacts with calcium channels in brain membranes.
Topics: Animals; Brain; Calcium; Carbamazepine; Clonazepam; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1984 |
Action of GP 47779, the active metabolite of oxcarbazepine, on the corticostriatal system. II. Modulation of high-voltage-activated calcium currents.
Topics: Animals; Anticonvulsants; Calcium Channels; Carbamazepine; Cell Separation; Cerebral Cortex; Corpus Striatum; Dihydropyridines; Glutamates; Male; Neural Pathways; Nifedipine; Oxcarbazepine; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Presynaptic; Synaptic Transmission | 1995 |
Chronological changes of MRI findings on striatal damage after acute cyanide intoxication: pathogenesis of the damage and its selectivity, and prevention for neurological sequelae: a case report.
Topics: Adult; Basal Ganglia; Brain Diseases; Carbamazepine; Corpus Striatum; Epilepsy, Temporal Lobe; Humans; Magnetic Resonance Imaging; Male; Nifedipine; Phenobarbital; Phenytoin; Potassium Cyanide; Suicide, Attempted | 1993 |
Protective effect of flunarizine and nifedipine alone and in combination with anticonvulsant drugs against PTZ-induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Female; Flunarizine; Male; Mice; Nifedipine; Pentylenetetrazole; Phenytoin; Seizures | 1993 |
Metabolism of carbamazepine by CYP3A6: a model for in vitro drug interactions studies.
Topics: Animals; Anti-Bacterial Agents; Antibodies; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Enzyme Inhibitors; Epilepsy; Hypnotics and Sedatives; In Vitro Techniques; Male; Microsomes, Liver; Nifedipine; Protein Isoforms; Rabbits | 1999 |
Carbamazepine decreases antihypertensive effect of nilvadipine.
Topics: Antihypertensive Agents; Antimanic Agents; Carbamazepine; Drug Interactions; Humans; Hypertension; Male; Middle Aged; Nifedipine | 2002 |
A compaction process to enhance dissolution of poorly water-soluble drugs using hydroxypropyl methylcellulose.
Topics: Carbamazepine; Chemistry, Pharmaceutical; Hypromellose Derivatives; Methylcellulose; Naproxen; Nifedipine; Solubility; Technology, Pharmaceutical | 2003 |
Dissolution rate improvement of poorly water-soluble drugs obtained by adsorbing solutions of drugs in hydrophilic solvents onto high surface area carriers.
Topics: Adsorption; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Drug Carriers; Excipients; Methanol; Nifedipine; Poloxamer; Polyethylene Glycols; Povidone; Pyrrolidinones; Silicon Dioxide; Solubility; Solvents; Surface Properties; Time Factors | 2006 |
Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction.
Topics: Algorithms; Carbamazepine; Cell Line; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Nifedipine; Phenobarbital; Phenytoin; Pioglitazone; Reproducibility of Results; Rifampin; Rosiglitazone; Sulfinpyrazone; Thiazolidinediones | 2006 |
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Glioma; Glutamic Acid; Lidocaine; Luminescence; Nickel; Nifedipine; Rats; Veratridine | 2008 |
Microbial degradation of pharmaceuticals in estuarine and coastal seawater.
Topics: Absorption; Antipyrine; Bacteria; Biodegradation, Environmental; Caffeine; Carbamazepine; Cotinine; Diltiazem; Ecology; Endocrine Disruptors; Half-Life; New York; Nifedipine; Pharmaceutical Preparations; Seawater; Solubility; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Microbiology; Water Pollutants, Chemical | 2009 |
Characterization and stability of solid dispersions based on PEG/polymer blends.
Topics: Carbamazepine; Drug Carriers; Drug Compounding; Drug Stability; Drug Storage; Nifedipine; Polyethylene Glycols; Polymers; Powders; Solubility; Transition Temperature; Wettability; X-Ray Diffraction | 2010 |
Simulation of clinical drug-drug interactions from hepatocyte CYP3A4 induction data and its potential utility in trial designs.
Topics: Area Under Curve; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Midazolam; Nifedipine; Phenobarbital; Rifampin; Simvastatin; Substrate Specificity | 2011 |
Dissolution and solid-state characterization of poorly water-soluble drugs in the presence of a hydrophilic carrier.
Topics: Calorimetry, Differential Scanning; Carbamazepine; Cellulose; Chemistry, Pharmaceutical; Crystallization; Crystallography, X-Ray; Drug Carriers; Drug Compounding; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Kinetics; Molecular Weight; Nifedipine; Solubility; Technology, Pharmaceutical; Wettability | 2011 |
[Clinical survey of tizanidine-induced adverse effects--impact of concomitant drugs providing cytochrome P450 1A2 modification--].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Blood Pressure; Carbamazepine; Clonidine; Cytochrome P-450 CYP1A2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; Heart Rate; Humans; Male; Middle Aged; Nifedipine; Retrospective Studies; Time Factors | 2013 |
Mechanisms for L-channel-mediated increase in [Ca(2+)]i and its reduction by anti-bipolar drugs in cultured astrocytes combined with its mRNA expression in freshly isolated cells support the importance of astrocytic L-channels.
Topics: Animals; Astrocytes; Brain; Calcium; Calcium Channels, L-Type; Carbamazepine; Cells, Cultured; Central Nervous System Depressants; Down-Regulation; Female; Ions; Lithium; Male; Mice; Mice, Transgenic; Nifedipine; Potassium; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; TRPC Cation Channels; Valproic Acid | 2013 |
Saturated fatty acids and fatty acid esters promote the polymorphic transition of clarithromycin metastable form I crystal.
Topics: Carbamazepine; Clarithromycin; Crystallization; Esters; Fatty Acids; Nifedipine; Phase Transition; Transition Temperature | 2016 |
Anticonvulsant effects of antiaris toxicaria aqueous extract: investigation using animal models of temporal lobe epilepsy.
Topics: Animals; Antiaris; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Administration Schedule; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred ICR; Nifedipine; Pentylenetetrazole; Pilocarpine; Plant Extracts; Rats; Rats, Sprague-Dawley | 2017 |